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Gilles Courtois

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Elodie Bégué; Armand Bensussan; Jean-Michel Cayuela; Gilles Courtois; Sébastien Jauliac; Francette Jean-Louis; Liliane Laroche; Hervé Bachelez; Martine Bagot; Nathalie Parquet; Laurence Michel
Inducible expression and pathophysiologic functions of T-plastin in cutaneous T-cell lymphoma.
Marion Bonnet; Gilles Courtois
[CYLD deubiquitinase as a recurrent target in oncogenic processes].
A-S Gabet; Séverine Coulon; A Fricot; Joël Vandekerckhove; Y Chang; Jean-Antoine Ribeil; L Lordier; Yael Zermati; Vahid Asnafi; Z Belaid; Najet Debili; William Vainchenker; Bruno Varet; Olivier Hermine; Gilles Courtois
Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling.

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All Publications

2012: Elodie Bégué; Armand Bensussan; Jean-Michel Cayuela; Gilles Courtois; Sébastien Jauliac; Francette Jean-Louis; Liliane Laroche; Hervé Bachelez; Martine Bagot; Nathalie Parquet; Laurence Michel
Inducible expression and pathophysiologic functions of T-plastin in cutaneous T-cell lymphoma.
Blood 2012;120(1):143-54.
2011: Marion Bonnet; Gilles Courtois
[CYLD deubiquitinase as a recurrent target in oncogenic processes].
Médecine sciences : M/S 2011;27(6-7):626-31.
2011: A-S Gabet; Séverine Coulon; A Fricot; Joël Vandekerckhove; Y Chang; Jean-Antoine Ribeil; L Lordier; Yael Zermati; Vahid Asnafi; Z Belaid; Najet Debili; William Vainchenker; Bruno Varet; Olivier Hermine; Gilles Courtois
Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling.
Cell death and differentiation 2011;18(4):678-89.
2010: Jérémie Gautheron; Alessandra Pescatore; Francesca Fusco; Elio Esposito; Shoji Yamaoka; Fabrice Agou; Matilde Valeria Ursini; Gilles Courtois
Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology.
Human molecular genetics 2010;19(16):3138-49.
2008: Gilles Courtois
Tumor suppressor CYLD: negative regulation of NF-kappaB signaling and more.
Cellular and molecular life sciences : CMLS 2008;65(7-8):1123-32.
2008: Aurore Sors; Francette Jean-Louis; Elodie Bégué; Laurent Parmentier; Louis Dubertret; Michel Dreano; Gilles Courtois; Hervé Bachelez; Laurence Michel
Inhibition of IkappaB kinase subunit 2 in cutaneous T-cell lymphoma down-regulates nuclear factor-kappaB constitutive activation, induces cell death, and potentiates the apoptotic response to antineoplastic chemotherapeutic agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(3):901-11.
2007: Hélène Sebban-Benin; Alessandra Pescatore; Francesca Fusco; Valérie Pascuale; Jérémie Gautheron; Shoji Yamaoka; Anne Moncla; Matilde Valeria Ursini; Gilles Courtois
Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.
Human molecular genetics 2007;16(23):2805-15.
2007: E Bal; Lekbir Baala; C Cluzeau; F El Kerch; Karim Ouldim; Smaïl Hadj-Rabia; Christine Bodemer; Arnold Munnich; Gilles Courtois; abdelaziz sefiani; Asma Smahi
Autosomal dominant anhidrotic ectodermal dysplasias at the EDARADD locus.
Human mutation 2007;28(7):703-9.
2007: Alla V Tsytsykova; James V Falvo; Marc Schmidt-Supprian; Gilles Courtois; Dimitris Thanos; Anne E Goldfeld
Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression.
The Journal of biological chemistry 2007;282(16):11629-38.
2006: Hélène Sebban; Shoji Yamaoka; Gilles Courtois
Posttranslational modifications of NEMO and its partners in NF-kappaB signaling.
Trends in cell biology 2006;16(11):569-77.
2006: Gilles Courtois; T D Gilmore
Mutations in the NF-kappaB signaling pathway: implications for human disease.
Oncogene 2006;25(51):6831-43.
2006: Hélène Sebban; Gilles Courtois
NF-kappaB and inflammation in genetic disease.
Biochemical pharmacology 2006;72(9):1153-60.
2006: Gilles Courtois; Asma Smahi
NF-kappaB-related genetic diseases.
Cell death and differentiation 2006;13(5):843-51.
2006: Aurore Sors; Francette Jean-Louis; Claire Pellet; Liliane Laroche; Louis Dubertret; Gilles Courtois; Hervé Bachelez; Laurence Michel
Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis.
Blood 2006;107(6):2354-63.
2006: Emilie Vinolo; Hélène Sebban; Alain Chaffotte; Alain Israël; Gilles Courtois; Michel Véron; Fabrice Agou
A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation.
The Journal of biological chemistry 2006;281(10):6334-48.
2005: Gilles Courtois
NF-kappaB in skin homeostasis.
Experimental dermatology 2005;14(10):781-2.
2005: Gilles Courtois
The NF-kappaB signaling pathway in human genetic diseases.
Cellular and molecular life sciences : CMLS 2005;62(15):1682-91.
2004: Fabrice Agou; Gilles Courtois; Jeanne Chiaravalli; Françoise Baleux; Yves-Marie Coïc; François Traincard; Alain Israël; Michel Véron
Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization.
The Journal of biological chemistry 2004;279(52):54248-57.
2004: Francesca Fusco; Tiziana Bardaro; Giorgia Fimiani; Vincenzo Mercadante; Maria Giuseppina Miano; Geppino Falco; Alain Israël; Gilles Courtois; Michele D'Urso; Matilde Valeria Ursini
Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation.
Human molecular genetics 2004;13(16):1763-73.
2004: Fabrice Agou; François Traincard; Emilie Vinolo; Gilles Courtois; Shoji Yamaoka; Alain Israël; Michel Véron
The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains.
The Journal of biological chemistry 2004;279(27):27861-9.
2004: Gilles Courtois; Alain Israël
[Human pathologies associated with NF-kappaB defects].
Journal de la Société de biologie 2004;198(2):93-6.
2003: Gilles Courtois; Asma Smahi; Janine Reichenbach; Rainer Döffinger; Caterina Cancrini; Marion Bonnet; Anne Puel; Christine Chable-Bessia; Shoji Yamaoka; Jacqueline Feinberg; Sophie Dupuis-Girod; Christine Bodemer; Susanna Livadiotti; Francesco Novelli; Paolo Rossi; Alain Fischer; Alain Israël; Arnold Munnich; Françoise Le Deist; Jean-Laurent Casanova
A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency.
The Journal of clinical investigation 2003;112(7):1108-15.
2003: Marc Schmidt-Supprian; Gilles Courtois; Jane Tian; Anthony J Coyle; Alain Israël; Klaus Rajewsky; Manolis Pasparakis
Mature T cells depend on signaling through the IKK complex.
Immunity 2003;19(3):377-89.
2003: Andrew Kovalenko; Christine Chable-Bessia; Giuseppina Cantarella; Alain Israël; David Wallach; Gilles Courtois
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.
Nature 2003;424(6950):801-5.
2002: Asma Smahi; Gilles Courtois; Smail Hadj Rabia; Rainer Döffinger; Christine Bodemer; Arnold Munnich; Jean-Laurent Casanova; Alain Israël
The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes.
Human molecular genetics 2002;11(20):2371-5.
2002: Lekbir Baala; Smaïl Hadj-Rabia; Dominique Hamel-Teillac; michelle hadchouel; Catherine Prost; Suzanne M Leal; Emmanuel Jacquemin; abdelaziz sefiani; Yves de Prost; Gilles Courtois; Arnold Munnich; Stanislas LYONNET; Pierre VABRES
Homozygosity mapping of a locus for a novel syndromic ichthyosis to chromosome 3q27-q28.
The Journal of investigative dermatology 2002;119(1):70-6.
2002: Manolis Pasparakis; Gilles Courtois; Martin Hafner; Marc Schmidt-Supprian; Arianna Nenci; Atiye Toksoy; Monika Krampert; Matthias Goebeler; Reinhard Gillitzer; Alain Israel; Thomas Krieg; Klaus Rajewsky; Ingo Haase
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2.
Nature 2002;417(6891):861-6.
2002: Sophie Dupuis-Girod; Nadège Corradini; Smaïl Hadj-Rabia; Jean-Christophe Fournet; Laurence Faivre; Françoise Le Deist; Philippe Durand; Rainer Döffinger; Asma Smahi; Alain Israel; Gilles Courtois; Nicole Brousse; Stéphane Blanche; Arnold Munnich; Alain Fischer; Jean-Laurent Casanova; Christine Bodemer
Osteopetrosis, lymphedema, anhidrotic ectodermal dysplasia, and immunodeficiency in a boy and incontinentia pigmenti in his mother.
Pediatrics 2002;109(6):e97.
2002: Fabrice Agou; Fei Ye; Stéphane Goffinont; Gilles Courtois; Shoji Yamaoka; Alain Israël; Michel Véron
NEMO trimerizes through its coiled-coil C-terminal domain.
The Journal of biological chemistry 2002;277(20):17464-75.
2001: Gilles Courtois; Asma Smahi; Alain Israël
NEMO/IKK gamma: linking NF-kappa B to human disease.
Trends in molecular medicine 2001;7(10):427-30.
2001: Rainer Döffinger; Asma Smahi; Christine Bessia; Frederic Geissmann; Jacqueline Feinberg; Anne Durandy; Christine Bodemer; Sue Kenwrick; Sophie Dupuis-Girod; Stéphane Blanche; P Wood; S H Rabia; Denis J Headon; Paul A Overbeek; Françoise Le Deist; Steven M Holland; K Belani; Dinakantha S Kumararatne; Alain Fischer; R Shapiro; M E Conley; E Reimund; H Kalhoff; M Abinun; Arnold Munnich; Alain Israël; Gilles Courtois; Jean-Laurent Casanova
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling.
Nature genetics 2001;27(3):277-85.
2001: Swaroop Aradhya; Gilles Courtois; Aleksandar Rajkovic; R A Lewis; M Levy; Alain Israël; David L Nelson
Atypical forms of incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-gamma).
American journal of human genetics 2001;68(3):765-71.
2000: Gilles Courtois; Alain Israël
NF-kappa B defects in humans: the NEMO/incontinentia pigmenti connection.
Science's STKE : signal transduction knowledge environment 2000;2000(58):pe1.
2000: Klaus Schwamborn; Robert Weil; Gilles Courtois; ST Whiteside; Alain Israël
Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway.
The Journal of biological chemistry 2000;275(30):22780-9.
2000: Marc Schmidt-Supprian; Wilhelm Bloch; Gilles Courtois; Klaus Addicks; Alain Israël; Klaus Rajewsky; Manolis Pasparakis
NEMO/IKK gamma-deficient mice model incontinentia pigmenti.
Molecular cell 2000;5(6):981-92.
2000: Asma Smahi; Gilles Courtois; Pierre VABRES; Shoji Yamaoka; Solange Heuertz; Arnold Munnich; Alain Israël; Nina S Heiss; Sabine M Klauck; Petra Kioschis; S Wiemann; Annemarie Poustka; Teresa Esposito; Tiziana Bardaro; Fernando Gianfrancesco; Alfredo Ciccodicola; Michele D'Urso; Hayley Woffendin; Tracy J Jakins; Dian Donnai; H Stewart; Sue Kenwrick; Swaroop Aradhya; Takanori Yamagata; M Levy; R A Lewis; David L Nelson
Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium.
Nature 2000;405(6785):466-72.
1998: Shoji Yamaoka; Gilles Courtois; Christine Bessia; ST Whiteside; Robert Weil; Fabrice Agou; HE Kirk; Robert J Kay; Alain Israël
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation.
Cell 1998;93(7):1231-40.
1997: Gilles Courtois; ST Whiteside; C H Sibley; Alain Israel
Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli.
Molecular and cellular biology 1997;17(3):1441-9.
1995: L Y Cohen; Gilles Courtois; M A Parant
Differentiation of murine pre-B cell line by an adjuvant muramyl peptide via NF-kappa B activation.
Immunobiology 1995;193(5):363-77.
1994: E Muñoz; Gilles Courtois; P Veschambre; Pierre Jalinot; Alain Israël
Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3.
Journal of virology 1994;68(12):8035-44.