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Charles Coutelle

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Procedures

Gene Therapy

Devices

Gene Transfer Techniques

Disorders

Living Beings

Physiology

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Molecular Sequence Data

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Co-Publications
Name
38
Themis, Michael
24
Waddington, Simon
21
Harbottle, Richard
14
Gregory, Lisa
14
Buckley, Suzanne
14
Speer, Astrid
12
Schneider, Holm
12
Bigger, Brian
12
Cook, Terry
10
Miller, Andrew
9
Nivsarkar, Megha
9
Peebles, Donald
9
Tolmachov, Oleg
7
Rodeck, Charles
7
Douar, Anne-Marie

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Publications

TOP 3
Wong Suet Ping; Argyros Orestis; Coutelle Charles; Harbottle Richard P
Strategies for the episomal modification of cells.
Argyros O; Wong S P; Niceta M; Waddington S N; Howe S J; Coutelle C; Miller A D; Harbottle R P
Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.
Buckley Suzanne M K; Howe Steven J; Rahim Ahad A; Buning Hildegard; McIntosh Jenny; Wong Suet-Ping; Baker Andrew H; Nathwani Amit; Thrasher Adrian J; Coutelle Charles; McKay Tristan R; Waddington Simon N
Luciferin detection after intranasal vector delivery is improved by intranasal rather than intraperitoneal luciferin administration.

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All Publications

2009: Wong Suet Ping; Argyros Orestis; Coutelle Charles; Harbottle Richard P
Strategies for the episomal modification of cells.
Current opinion in molecular therapeutics 2009;11(4):433-41.
2008: Argyros O; Wong S P; Niceta M; Waddington S N; Howe S J; Coutelle C; Miller A D; Harbottle R P
Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.
Gene therapy 2008;15(24):1593-605.
2008: Buckley Suzanne M K; Howe Steven J; Rahim Ahad A; Buning Hildegard; McIntosh Jenny; Wong Suet-Ping; Baker Andrew H; Nathwani Amit; Thrasher Adrian J; Coutelle Charles; McKay Tristan R; Waddington Simon N
Luciferin detection after intranasal vector delivery is improved by intranasal rather than intraperitoneal luciferin administration.
Human gene therapy 2008;19(10):1050-6.
2008: Buckley S M K; Howe S J; Sheard V; Ward N J; Coutelle C; Thrasher A J; Waddington S N; McKay T R
Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression.
Gene therapy 2008;15(16):1167-75.
2008: Buckley Suzanne M K; Waddington S N; Jezzard S; Bergau A; Themis M; MacVinish L J; Cuthbert A W; Colledge W H; Coutelle C
Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):819-24.
2008: Coutelle Charles
Why bother? Is in utero gene therapy worth the effort?
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(2):219-20.
2007: Waddington Simon N; Buckley Suzanne Mk; David Anna L; Peebles Donald M; Rodeck Charles H; Coutelle Charles
Fetal gene transfer.
Current opinion in molecular therapeutics 2007;9(5):432-8.
2007: Hibbitt Olivia C; Harbottle Richard P; Waddington Simon N; Bursill Christine A; Coutelle Charles; Channon Keith M; Wade-Martins Richard
Delivery and long-term expression of a 135 kb LDLR genomic DNA locus in vivo by hydrodynamic tail vein injection.
The journal of gene medicine 2007;9(6):488-97.
2007: Tolmachov Oleg; Coutelle Charles
Covalent attachment of multifunctional chimeric terminal proteins to 5' DNA ends: A potential new strategy for assembly of synthetic therapeutic gene vectors.
Medical hypotheses 2007;68(2):328-31.
2006: David A L; Peebles D M; Gregory L; Waddington S N; Themis M; Weisz B; Ruthe A; Lawrence L; Cook T; Rodeck C H; Coutelle C
Clinically applicable procedure for gene delivery to fetal gut by ultrasound-guided gastric injection: toward prenatal prevention of early-onset intestinal diseases.
Human gene therapy 2006;17(7):767-79.
2006: David A L; Weisz B; Gregory L; Themis M; Cook T; Roubliova X; Deprest J; Coutelle C; Rodeck C H; Peebles D M
Ultrasound-guided injection and occlusion of the trachea in fetal sheep.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;28(1):82-8.
2006: Vaysse Laurence; Gregory Lisa G; Harbottle Richard P; Perouzel Eric; Tolmachov Oleg; Coutelle Charles
Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo.
The journal of gene medicine 2006;8(6):754-63.
2006: Bigger B W; Siapati E K; Mistry A; Waddington S N; Nivsarkar M S; Jacobs L; Perrett R; Holder M V; Ridler C; Kemball-Cook G; Ali R R; Forbes S J; Coutelle C; Wright N; Alison M; Thrasher A J; Bonnet D; Themis M
Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX.
Gene therapy 2006;13(2):117-26.
2006: Tolmachov Oleg; Ma Yu-Ling; Themis Michael; Patel Pravina; Spohr Hilmar; Macleod Kenneth T; Ullrich Nina D; Kienast Yvonne; Coutelle Charles; Peters Nicholas S
Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro.
BMC cardiovascular disorders 2006;6():25.
2006: Tolmachov Oleg; Palaszewski Iwona; Bigger Brian; Coutelle Charles
RecET driven chromosomal gene targeting to generate a RecA deficient Escherichia coli strain for Cre mediated production of minicircle DNA.
BMC biotechnology 2006;6():17.
2005: Coutelle C; Themis M; Waddington S N; Buckley S M K; Gregory L G; Nivsarkar M S; David A L; Peebles D; Weisz B; Rodeck C
Gene therapy progress and prospects: fetal gene therapy--first proofs of concept--some adverse effects.
Gene therapy 2005;12(22):1601-7.
2005: Themis Mike; Waddington Simon N; Schmidt Manfred; von Kalle Christof; Wang Yoahe; Al-Allaf Faisal; Gregory Lisa G; Nivsarkar Megha; Themis Matthew; Holder Maxine V; Buckley Suzanne M K; Dighe Niraja; Ruthe Alaine T; Mistry Ajay; Bigger Brian; Rahim Ahad; Nguyen Tuan H; Trono Didier; Thrasher Adrian J; Coutelle Charles
Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(4):763-71.
2005: Weisz Boaz; David Anna L; Gregory Lisa G; Perocheau Dany; Ruthe Ali; Waddington Simon N; Themis Mike; Cook Terry; Coutelle Charles; Rodeck Charles H; Peebles Donald M
Targeting the respiratory muscles of fetal sheep for prenatal gene therapy for Duchenne muscular dystrophy.
American journal of obstetrics and gynecology 2005;193(3 Pt 2):1105-9.
2005: Buckley S M K; Waddington S N; Jezzard S; Lawrence L; Schneider H; Holder M V; Themis M; Coutelle C
Factors influencing adenovirus-mediated airway transduction in fetal mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):484-92.
2005: Al-Allaf Faisal A; Tolmachov Oleg; Themis Michael; Coutelle Charles
Coupled analysis of bacterial transformants and ligation mixture by duplex PCR enables detection of fatal instability of a nascent recombinant plasmid.
Journal of biochemical and biophysical methods 2005;64(2):142-6.
2005: Waterhouse Jodie E; Harbottle Richard P; Keller Michael; Kostarelos Kostas; Coutelle Charles; Jorgensen Michael R; Miller Andrew D
Synthesis and application of integrin targeting lipopeptides in targeted gene delivery.
Chembiochem : a European journal of chemical biology 2005;6(7):1212-23.
2005: Waddington Simon N; Kramer M Gabriela; Hernandez-Alcoceba Ruben; Buckley Suzanne M K; Themis Michael; Coutelle Charles; Prieto Jesus
In utero gene therapy: current challenges and perspectives.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(5):661-76.
2005: Al-Allaf Faisal; Tolmachov Oleg; Themis Michael; Coutelle Charles
Accurate size gauging of ExoIII/S1-generated deletions by PCR analysis of ligation mixtures.
Analytical biochemistry 2005;339(2):348-50.
2005: Hoare Jonathan; Waddington Simon; Thomas Howard C; Coutelle Charles; McGarvey Michael J
Complement inhibition rescued mice allowing observation of transgene expression following intraportal delivery of baculovirus in mice.
The journal of gene medicine 2005;7(3):325-33.
2004: Waddington Simon N; Nivsarkar Megha S; Mistry Ajay R; Buckley Suzanne M K; Kemball-Cook Geoffrey; Mosley Karen L; Mitrophanous Kyriacos; Radcliffe Pippa; Holder Maxine V; Brittan Mairi; Georgiadis Anastasios; Al-Allaf Faisal; Bigger Brian W; Gregory Lisa G; Cook H Terence; Ali Robin R; Thrasher Adrian; Tuddenham Edward G D; Themis Mike; Coutelle Charles
Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy.
Blood 2004;104(9):2714-21.
2004: Waddington S N; Kennea N L; Buckley S M K; Gregory L G; Themis M; Coutelle C
Fetal and neonatal gene therapy: benefits and pitfalls.
Gene therapy 2004;11 Suppl 1():S92-7.
2004: Gregory L G; Waddington S N; Holder M V; Mitrophanous K A; Buckley S M K; Mosley K L; Bigger B W; Ellard F M; Walmsley L E; Lawrence L; Al-Allaf F; Kingsman S; Coutelle C; Themis M
Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy.
Gene therapy 2004;11(14):1117-25.
2004: Waddington S N; Buckley S M K; Bernloehr C; Bossow S; Ungerechts G; Cook T; Gregory L; Rahim A; Themis M; Neubert W J; Coutelle C; Lauer U M; Bitzer M
Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus.
Gene therapy 2004;11(7):599-608.
2004: Vaysse Laurence; Harbottle Richard; Bigger Brian; Bergau Anna; Tolmachov Oleg; Coutelle Charles
Development of a self-assembling nuclear targeting vector system based on the tetracycline repressor protein.
The Journal of biological chemistry 2004;279(7):5555-64.
2004: Peebles D; Gregory L G; David A; Themis M; Waddington S N; Knapton H J; Miah M; Cook T; Lawrence L; Nivsarkar M; Rodeck C; Coutelle C
Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero.
Gene therapy 2004;11(1):70-8.
2003: Coutelle C; Themis M; Waddington S; Gregory L; Nivsarkar M; Buckley S; Cook T; Rodeck C; Peebles D; David A
The hopes and fears of in utero gene therapy for genetic disease--a review.
Placenta 2003;24 Suppl B():S114-21.
2003: Themis M; May D; Coutelle C; Newbold R F
Mutational effects of retrovirus insertion on the genome of V79 cells by an attenuated retrovirus vector: implications for gene therapy.
Gene therapy 2003;10(19):1703-11.
2003: David A L; Peebles D M; Gregory L; Themis M; Cook T; Coutelle C; Rodeck C H
Percutaneous ultrasound-guided injection of the trachea in fetal sheep: a novel technique to target the fetal airways.
Fetal diagnosis and therapy 2003;18(5):385-90.
2003: Rahim Ahad; Coutelle Charles; Harbottle Richard
High-throughput Pyrosequencing of a phage display library for the identification of enriched target-specific peptides.
BioTechniques 2003;35(2):317-20, 322, 324.
2003: Waddington S N; Mitrophanous K A; Ellard F M; Buckley S M K; Nivsarkar M; Lawrence L; Cook H T; Al-Allaf F; Bigger B; Kingsman S M; Coutelle C; Themis M
Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice.
Gene therapy 2003;10(15):1234-40.
2003: Keller Michael; Harbottle Richard P; Perouzel Eric; Colin Morvane; Shah Imran; Rahim Ahad; Vaysse Laurence; Bergau Anna; Moritz Sylviane; Brahimi-Horn Christiane; Coutelle Charles; Miller Andrew D
Nuclear localisation sequence templated nonviral gene delivery vectors: investigation of intracellular trafficking events of LMD and LD vector systems.
Chembiochem : a European journal of chemical biology 2003;4(4):286-98.
2003: David Anna; Cook Terry; Waddington Simon; Peebles Donald; Nivsarkar Megha; Knapton Holly; Miah Maznu; Dahse Thomas; Noakes David; Schneider Holm; Rodeck Charles; Coutelle Charles; Themis Mike
Ultrasound-guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero.
Human gene therapy 2003;14(4):353-64.
2003: Waddington Simon N; Buckley Suzanne M K; Nivsarkar Megha; Jezzard Sarah; Schneider Holm; Dahse Thomas; Kemball-Cook Geoff; Miah Maznu; Tucker Nick; Dallman Margaret J; Themis Mike; Coutelle Charles
In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor.
Blood 2003;101(4):1359-66.
2003: Gregory Lisa G; Harbottle Richard P; Lawrence Lorraine; Knapton Holly J; Themis Michael; Coutelle Charles
Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(1):19-26.
2003: Moritz S; Colin M; Keller M; Klonjkowski B; Capeau J; Coutelle C; Chroboczek J; Brahimi-Horn M C
Gene transfer by adenovirus-mimetic peptides in the presence of a cationic lipid and/or adenovirus. Analysis of the contribution of the viral and nonviral components.
Archives of virology 2003;148(1):1-18.
2002: Coutelle C; Rodeck C
On the scientific and ethical issues of fetal somatic gene therapy.
Gene therapy 2002;9(11):670-3.
2002: Tagawa T; Manvell M; Brown N; Keller M; Perouzel E; Murray K D; Harbottle R P; Tecle M; Booy F; Brahimi-Horn M C; Coutelle C; Lemoine N R; Alton E W F W; Miller A D
Characterisation of LMD virus-like nanoparticles self-assembled from cationic liposomes, adenovirus core peptide mu and plasmid DNA.
Gene therapy 2002;9(9):564-76.
2002: McKay Tristan; Reynolds Paul; Jezzard Sarah; Curiel David; Coutelle Charles
Secretin-mediated gene delivery, a specific targeting mechanism with potential for treatment of biliary and pancreatic disease in cystic fibrosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(4):447-54.
2002: Schneider Holm; Mühle Christiane; Douar Anne Marie; Waddington Simon; Jiang Qiu-Jie; von der Mark Klaus; Coutelle Charles; Rascher Wolfgang
Sustained delivery of therapeutic concentrations of human clotting factor IX--a comparison of adenoviral and AAV vectors administered in utero.
The journal of gene medicine 2002;4(1):46-53.
2001: Colin M; Moritz S; Fontanges P; Kornprobst M; Delouis C; Keller M; Miller A D; Capeau J; Coutelle C; Brahimi-Horn M C
The nuclear pore complex is involved in nuclear transfer of plasmid DNA condensed with an oligolysine-RGD peptide containing nuclear localisation properties.
Gene therapy 2001;8(21):1643-53.
2001: Coutelle C; Bigger B
[Gene therapy of cystic fibrosis; review of completed clinical studies]
Der Internist 2001;42(10):1346-50, 1353-6.
2001: Bigger B W; Tolmachov O; Collombet J M; Fragkos M; Palaszewski I; Coutelle C
An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.
The Journal of biological chemistry 2001;276(25):23018-27.
2001: Chan L M; Coutelle C; Themis M
A novel human suspension culture packaging cell line for production of high-titre retroviral vectors.
Gene therapy 2001;8(9):697-703.
2001: Jost P J; Harbottle R P; Knight A; Miller A D; Coutelle C; Schneider H
A novel peptide, THALWHT, for the targeting of human airway epithelia.
FEBS letters 2001;489(2-3):263-9.
2001: Bigger B; Coutelle C
Perspectives on gene therapy for cystic fibrosis airway disease.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2001;15(9):615-34.
2001: Coutelle C; Themis M; Schneider H; Kiserud T; Cook T; Douar A M; Hanson M; Pavirani A; Rodeck C
Fetal somatic gene therapy--a preventive approach to the treatment of genetic disease: the case for.
Ernst Schering Research Foundation workshop 2001;(33):99-114.
2000: Schneider H; Groves M; Mühle C; Reynolds P N; Knight A; Themis M; Carvajal J; Scaravilli F; Curiel D T; Fairweather N F; Coutelle C
Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin.
Gene therapy 2000;7(18):1584-92.
2000: Colin M; Moritz S; Schneider H; Capeau J; Coutelle C; Brahimi-Horn M C
Haemoglobin interferes with the ex vivo luciferase luminescence assay: consequence for detection of luciferase reporter gene expression in vivo.
Gene therapy 2000;7(15):1333-6.
2000: Forbes S J; Themis M; Alison M R; Shiota A; Kobayashi T; Coutelle C; Hodgson H J
Tri-iodothyronine and a deleted form of hepatocyte growth factor act synergistically to enhance liver proliferation and enable in vivo retroviral gene transfer via the peripheral venous system.
Gene therapy 2000;7(9):784-9.
2000: McKay T R; MacVinish L J; Carpenter B; Themis M; Jezzard S; Goldin R; Pavirani A; Hickman M E; Cuthbert A W; Coutelle C
Selective in vivo transfection of murine biliary epithelia using polycation-enhanced adenovirus.
Gene therapy 2000;7(8):644-52.
2000: Forbes S J; Themis M; Alison M R; Sarosi I; Coutelle C; Hodgson H J
Synergistic growth factors enhance rat liver proliferation and enable retroviral gene transfer via a peripheral vein.
Gastroenterology 2000;118(3):591-8.
2000: Colin M; Maurice M; Trugnan G; Kornprobst M; Harbottle R P; Knight A; Cooper R G; Miller A D; Capeau J; Coutelle C; Brahimi-Horn M C
Cell delivery, intracellular trafficking and expression of an integrin-mediated gene transfer vector in tracheal epithelial cells.
Gene therapy 2000;7(2):139-52.
2000: Bigger B; Tolmachov O; Collombet J M; Coutelle C
Introduction of chloramphenicol resistance into the modified mouse mitochondrial genome: cloning of unstable sequences by passage through yeast.
Analytical biochemistry 2000;277(2):236-42.
1999: Bigger B; Collombet J M; Coutelle C
Tipping the scales in favour of mitochondrial gene therapy.
Gene therapy 1999;6(12):1909-10.
1999: Schneider H; Adebakin S; Themis M; Cook T; Douar A M; Pavirani A; Coutelle C
Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B.
The journal of gene medicine 1999;1(6):424-32.
1999: Schneider H; Harbottle R P; Yokosaki Y; Jost P; Coutelle C
Targeted gene delivery into alpha9beta1-integrin-displaying cells by a synthetic peptide.
FEBS letters 1999;458(3):329-32.
1999: Themis M; Schneider H; Kiserud T; Cook T; Adebakin S; Jezzard S; Forbes S; Hanson M; Pavirani A; Rodeck C; Coutelle C
Successful expression of beta-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein.
Gene therapy 1999;6(7):1239-48.
1999: Schneider H; Coutelle C
In utero gene therapy: the case for.
Nature medicine 1999;5(3):256-7.
1999: Knight A; Carvajal J; Schneider H; Coutelle C; Chamberlain S; Fairweather N
Non-viral neuronal gene delivery mediated by the HC fragment of tetanus toxin.
European journal of biochemistry / FEBS 1999;259(3):762-9.
1998: Colin M; Harbottle R P; Knight A; Kornprobst M; Cooper R G; Miller A D; Trugnan G; Capeau J; Coutelle C; Brahimi-Horn M C
Liposomes enhance delivery and expression of an RGD-oligolysine gene transfer vector in human tracheal cells.
Gene therapy 1998;5(11):1488-98.
1998: Themis M; Forbes S J; Chan L; Cooper R G; Etheridge C J; Miller A D; Hodgson H J; Coutelle C
Enhanced in vitro and in vivo gene delivery using cationic agent complexed retrovirus vectors.
Gene therapy 1998;5(9):1180-6.
1998: Schneider H; Harbottle R P; Yokosaki Y; Kunde J; Sheppard D; Coutelle C
A novel peptide, PLAEIDGIELTY, for the targeting of alpha9beta1-integrins.
FEBS letters 1998;429(3):269-73.
1998: Harbottle R P; Cooper R G; Hart S L; Ladhoff A; McKay T; Knight A M; Wagner E; Miller A D; Coutelle C
An RGD-oligolysine peptide: a prototype construct for integrin-mediated gene delivery.
Human gene therapy 1998;9(7):1037-47.
1998: Forbes S J; Themis M; Alison M R; Selden C; Coutelle C; Hodgson H J
Retroviral gene transfer to the liver in vivo during tri-iodothyronine induced hyperplasia.
Gene therapy 1998;5(4):552-5.
1998: Hart S L; Arancibia-Cárcamo C V; Wolfert M A; Mailhos C; O'Reilly N J; Ali R R; Coutelle C; George A J; Harbottle R P; Knight A M; Larkin D F; Levinsky R J; Seymour L W; Thrasher A J; Kinnon C
Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector.
Human gene therapy 1998;9(4):575-85.
1998: Collombet J M; Coutelle C
Towards gene therapy of mitochondrial disorders.
Molecular medicine today 1998;4(1):31-8.
1997: Wheeler V C; Aitken M; Coutelle C
Modification of the mouse mitochondrial genome by insertion of an exogenous gene.
Gene 1997;198(1-2):203-9.
1997: Douar A M; Adebakin S; Themis M; Pavirani A; Cook T; Coutelle C
Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus.
Gene therapy 1997;4(9):883-90.
1997: Mayall E S; Coutelle C
RT-PCR method specific for the detection of transgenic CFTR mRNA in the presence of transgene plasmid DNA and endogenous CFTR mRNA.
Gene therapy 1997;4(8):875-8.
1997: Shiels C; Coutelle C; Huxley C
Contiguous arrays of satellites 1, 3, and beta form a 1.5-Mb domain on chromosome 22p.
Genomics 1997;44(1):35-44.
1997: Behrens F; Claussen U; Iyer L M; Green E D; Horsthemke B; Williamson R; Huxley C; Coutelle C
Isolation of DNA from the centromere of human chromosome 7 by microdissection.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1997;5(4):215-20.
1997: Mistry A R; Falciola L; Monaco L; Tagliabue R; Acerbis G; Knight A; Harbottle R P; Soria M; Bianchi M E; Coutelle C; Hart S L
Recombinant HMG1 protein produced in Pichia pastoris: a nonviral gene delivery agent.
BioTechniques 1997;22(4):718-29.
1997: Collombet J M; Wheeler V C; Vogel F; Coutelle C
Introduction of plasmid DNA into isolated mitochondria by electroporation. A novel approach toward gene correction for mitochondrial disorders.
The Journal of biological chemistry 1997;272(8):5342-7.
1997: Shiels C; Coutelle C; Huxley C
Analysis of ribosomal and alphoid repetitive DNA by fiber-FISH.
Cytogenetics and cell genetics 1997;76(1-2):20-2.
1996: Villaverde A; Feliu J X; Harbottle R P; Benito A; Coutelle C
A recombinant, arginine-glycine-aspartic acid (RGD) motif from foot-and-mouth disease virus binds mammalian cells through vitronectin and, to a lower extent, fibronectin receptors.
Gene 1996;180(1-2):101-6.
1996: Douar A M; Themis M; Coutelle C
Fetal somatic gene therapy.
Molecular human reproduction 1996;2(9):633-41.
1996: Douar A M; Themis M; Sandig V; Friedmann T; Coutelle C
Effect of amniotic fluid on cationic lipid mediated transfection and retroviral infection.
Gene therapy 1996;3(9):789-96.
1996: Wheeler V C; Prodromou C; Pearl L H; Williamson R; Coutelle C
Synthesis of a modified gene encoding human ornithine transcarbamylase for expression in mammalian mitochondrial and universal translation systems: a novel approach towards correction of a genetic defect.
Gene 1996;169(2):251-5.
1995: Caplen N J; Kinrade E; Sorgi F; Gao X; Gruenert D; Geddes D; Coutelle C; Huang L; Alton E W; Williamson R
In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE.
Gene therapy 1995;2(9):603-13.
1995: Hart S L; Harbottle R P; Cooper R; Miller A; Williamson R; Coutelle C
Gene delivery and expression mediated by an integrin-binding peptide.
Gene therapy 1995;2(8):552-4.
1995: Hart S L; Mayall E; Stern M; Munkonge F M; Frost A; Huang L; Vasilliou M; Williamson R; Alton E W; Coutelle C
The introduction of two silent mutations into a CFTR cDNA construct allows improved detection of exogenous mRNA in gene transfer experiments.
Human molecular genetics 1995;4(9):1597-602.
1995: Coutelle C; Douar A M; Colledge W H; Froster U
The challenge of fetal gene therapy.
Nature medicine 1995;1(9):864-6.
1995: Wheeler V C; Coutelle C
Nondegradative in vitro labeling of plasmid DNA.
Analytical biochemistry 1995;225(2):374-6.
1995: Caplen N J; Alton E W; Middleton P G; Dorin J R; Stevenson B J; Gao X; Durham S R; Jeffery P K; Hodson M E; Coutelle C
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.
Nature medicine 1995;1(1):39-46.
1994: Grade K; Grunewald I; Graupner I; Behrens F; Coutelle C
Identification of three novel mutations in the CFTR gene using temperature-optimized non-radioactive conditions for SSCP analysis.
Human genetics 1994;94(2):154-8.
1994: Jung U; Urner U; Grade K; Coutelle C
Acceptability of carrier screening for cystic fibrosis during pregnancy in a German population.
Human genetics 1994;94(1):19-24.
1994: Hart S L; Knight A M; Harbottle R P; Mistry A; Hunger H D; Cutler D F; Williamson R; Coutelle C
Cell binding and internalization by filamentous phage displaying a cyclic Arg-Gly-Asp-containing peptide.
The Journal of biological chemistry 1994;269(17):12468-74.
1993: Coutelle C; Caplen N; Hart S; Huxley C; Williamson R
Gene therapy for cystic fibrosis.
Archives of disease in childhood 1993;68(4):437-40.
1992: Coutelle C; Brückner R; Grade K; Behrens F; Gedschold J; Hein J; Szibor R; Bauer I; Brock J; Graupner I
Prevalence of cystic fibrosis mutations in the East German population.
Human mutation 1992;1(2):109-12.
1992: Coutelle C; Grade K
[Molecular biological analysis of cystic fibrosis--a model example for the strategy of "reverse genetics"]
Pädiatrie und Grenzgebiete 1992;31(2):73-95.
1991: Coutelle C; Grade K; Brückner R; Szibor R; Will K; Bauer I; Gorki H; Gedschold J; Brock J; Urner U
CF DNA-diagnosis and gene mutation analysis: data from East Germany.
Pathologie-biologie 1991;39(6):585-6.
1991: Gille C; Grade K; Coutelle C
A pooling strategy for heterozygote screening of the delta F508 cystic fibrosis mutation.
Human genetics 1991;86(3):289-91.
1991: Coutelle C; Grade K; Speer A; Will K; Gille C; Szibor R; Gedschold J; Brückner R; Steinbicker V; Bauer I
Present state of DNA-diagnosis for cystic fibrosis and attitudes concerning a heterozygote screening in the GDR.
Advances in experimental medicine and biology 1991;290():75-8; discussion 78-81.
1990: Speer A; Kräft U; Hanke R; Grade K; Coutelle C; Wulff K; Wehnert M; Herrmann F H; Kadasi L; Kunert E
Deletion analysis of DMD/BMD families from the German Democratic Republic and selected regions of Czechoslovakia and Hungary.
Journal of medical genetics 1990;27(11):679-82.
1990: Hunger H D; Flachmeier C; Schmidt G; Behrendt G; Coutelle C
Ultrasensitive enzymatic radioimmunoassay using a fusion protein of protein A and neomycin phosphotransferase II in two-chamber-well microtiter plates.
Analytical biochemistry 1990;187(1):89-93.
1990: Hunger H D; Schmidt G; Flachmeier C; Behrendt G; Coutelle C
High-sensitivity protein detection by a new "contact-copy" method using a protein A-neomycin phosphotransferase II fusion protein.
Analytical biochemistry 1990;186(1):159-64.
1990: Speer A; Billwitz H; Huth A; Hanke R; Coutelle C; England S; Love D; Davies K E
Mapping and sequencing in two intron regions of the human dystrophin gene.
Biomedica biochimica acta 1990;49(4):K1-2.
1989: Riess O; Michel A; Berger W; Nürnberg P; Epplen J T; Speer A; Coutelle C
RFLP-discordance within the human phenylalanine hydroxylase locus.
Human genetics 1989;83(2):199-201.
1989: Huth A; Estivill X; Grade K; Billwitz H; Speer A; Rosenthal A; Williamson R; Ramsay M; Coutelle C
Polymerase chain reaction for detection of the pMP6d-9/MspI RFLP, a marker closely linked to the cystic fibrosis mutation.
Nucleic acids research 1989;17(17):7118.
1989: Speer A; Rosenthal A; Billwitz H; Hanke R; Forrest S M; Love D; Davies K E; Coutelle C
DNA amplification of a further exon of Duchenne muscular dystrophy locus increase possibilities for deletion screening.
Nucleic acids research 1989;17(12):4892.
1989: Merkel D; Schmidt G; Flachmeier C; Behrendt G; Coutelle C; Hunger H D
A new neomycin phosphotransferase II solid phase assay in combination with polyacrylamide sodium dodecylsulphate gel electrophoresis.
Journal of biochemical and biophysical methods 1989;18(4):277-85.
1989: Coutelle C; Speer A; Grade K; Rosenthal A; Hunger H D
[The development of molecular human genetics and its significance for perspectives of modern medicine]
Pädiatrie und Grenzgebiete 1989;28(6):319-46.
1988: Hunger H D; Flachmeier C; Schmidt G; Behrendt G; Coutelle C
A protein-free blocking system for the covalently binding matrix cyanuric chloride-activated paper in immunological procedures.
Journal of biochemical and biophysical methods 1988;17(1):43-50.
1988: Riess O; Michel A; Speer A; Meiske W; Cobet G; Coutelle C
Linkage disequilibrium between RFLP haplotype 2 and the affected PAH allele in PKU families from the Berlin area of the German Democratic Republic.
Human genetics 1988;78(4):343-6.
1987: Riess O; Michel A; Speer A; Cobet G; Coutelle C
Introduction of genomic diagnosis of classical phenylketonuria to the health care system of the German Democratic Republic.
Clinical genetics 1987;32(4):209-15.
1987: Berger W; Hein J; Gedschold J; Bauer I; Speer A; Farrall M; Williamson R; Coutelle C
Crossovers in two German cystic fibrosis families determine probe order for MET, 7C22 and XV-2c/CS.7.
Human genetics 1987;77(2):197-9.
1987: Hunger H D; Speer A; Flachmeier C; Hanke R; Behrendt G; Coutelle C
Use of cyanuric chloride-activated paper for detection of subpicogram quantities of specific DNA sequences and its application to linked restriction fragment length polymorphism analysis in a Duchenne muscular dystrophy affected family.
Analytical biochemistry 1987;165(1):45-55.
1987: Dietzsch H J; Coutelle C; Hein J
[Possibilities and limits of gene technology diagnosis of cystic fibrosis]
Kinderärztliche Praxis 1987;55(6):279-82.
1986: Speer A; Bollman R; Michel A; Neumann R; Bommer C; Hanke R; Riess O; Cobet G; Coutelle C
Prenatal diagnosis of classical phenylketonuria by linked restriction fragment length polymorphism analysis.
Prenatal diagnosis 1986;6(6):447-50.
1986: Hunger H D; Coutelle C; Behrendt G; Flachmeier C; Rosenthal A; Speer A; Breter H; Szargan R; Franke P; Stahl J
CCA paper: a new two-dimensional cyanuric chloride-activated matrix for universal application in molecular biology.
Analytical biochemistry 1986;156(2):286-99.
1986: Speer A; Dahl H H; Riess O; Cobet G; Hanke R; Cotton R G; Coutelle C
Typing of families with classical phenylketonuria using three alleles of the Hindiii linked restriction fragment polymorphism, detectable with a phenylalanine hydroxylase cDNA probe. Family typing for PKU by linked HindIII RFLP.
Clinical genetics 1986;29(6):491-5.
1986: Speer A; Davies K; McGlade S; Hanke R; Spiegler A W; Szibor R; Sommer D; Herrmann F; Coutelle C
Possibilities and problems in genomic diagnosis of Duchenne muscular dystrophy with molecular probes.
Biomedica biochimica acta 1986;45(7):K19-27.

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