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Sonia Covaceuszach

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Sonia Covaceuszach; Ivet Krastanova; Doriano Lamba; Sara Marinelli; Flaminia Pavone; Gabriele Ugolini; Antonino Cattaneo
Single cycle structure-based humanization of an anti-nerve growth factor therapeutic antibody.
Simona Capsoni; Sonia Covaceuszach; Sara Marinelli; Marcello Ceci; Antonietta Bernardo; Luisa Minghetti; Gabriele Ugolini; Flaminia Pavone; Antonino Cattaneo
Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity.
Sonia Covaceuszach; Simona Capsoni; Sara Marinelli; Flaminia Pavone; Marcello Ceci; Gabriele Ugolini; Domenico Vignone; Gianluca Amato; Francesca Paoletti; Doriano Lamba; Antonino Cattaneo
In vitro receptor binding properties of a "painless" NGF mutein, linked to hereditary sensory autonomic neuropathy type V.

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All Publications

2012: Sonia Covaceuszach; Ivet Krastanova; Doriano Lamba; Sara Marinelli; Flaminia Pavone; Gabriele Ugolini; Antonino Cattaneo
Single cycle structure-based humanization of an anti-nerve growth factor therapeutic antibody.
PloS one 2012;7(3):e32212.
2011: Simona Capsoni; Sonia Covaceuszach; Sara Marinelli; Marcello Ceci; Antonietta Bernardo; Luisa Minghetti; Gabriele Ugolini; Flaminia Pavone; Antonino Cattaneo
Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity.
PloS one 2011;6(2):e17321.
2010: Sonia Covaceuszach; Simona Capsoni; Sara Marinelli; Flaminia Pavone; Marcello Ceci; Gabriele Ugolini; Domenico Vignone; Gianluca Amato; Francesca Paoletti; Doriano Lamba; Antonino Cattaneo
In vitro receptor binding properties of a "painless" NGF mutein, linked to hereditary sensory autonomic neuropathy type V.
Biochemical and biophysical research communications 2010;391(1):824-9.
2009: Francesca Paoletti; Sonia Covaceuszach; Peter V Konarev; Stefania Gonfloni; Francesca Malerba; Elisabeth Schwarz; Dmitri I Svergun; Antonino Cattaneo; Doriano Lamba
Intrinsic structural disorder of mouse proNGF.
Proteins 2009;75(4):990-1009.
2009: Sonia Covaceuszach; Simona Capsoni; Gatsuella Ugolini; F Spirito; D Vignone; Antonio Cattaneo
Development of a non invasive NGF-based therapy for Alzheimer's disease.
Current Alzheimer research 2009;6(2):158-70.
2009: Simona Capsoni; Sonia Covaceuszach; Gabriele Ugolini; Francesca Spirito; Domenico Vignone; Barbara Stefanini; Gianluca Amato; Antonino Cattaneo
Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice.
Journal of Alzheimer's disease : JAD 2009;16(2):371-88.
2008: Sonia Covaceuszach; Alberto Cassetta; Petr V Konarev; Stefania Gonfloni; Rainer Rudolph; Dmitri I Svergun; Doriano Lamba; Antonino Cattaneo
Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody.
Journal of molecular biology 2008;381(4):881-96.
2007: Gabriele Ugolini; Sara Marinelli; Sonia Covaceuszach; Antonino Cattaneo; Flaminia Pavone
The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2985-90.
2006: F Paoletti; Peter V Konarev; Sonia Covaceuszach; E Schwarz; Antonino Cattaneo; Doriano Lamba; Dmitri I Svergun
Structural and functional properties of mouse proNGF.
Biochemical Society transactions 2006;34(Pt 4):605-6.
2005: Sonia Covaceuszach; Antonino Cattaneo; Doriano Lamba
Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight.
Proteins 2005;58(3):717-27.
2004: Alfredo Brancucci; Nicola Kuczewski; Sonia Covaceuszach; Antonino Cattaneo; Luciano Domenici
Nerve growth factor favours long-term depression over long-term potentiation in layer II-III neurones of rat visual cortex.
The Journal of physiology 2004;559(Pt 2):497-506.
2004: Sonia Covaceuszach; Alberto Cassetta; Antonino Cattaneo; Doriano Lamba
Purification, crystallization, X-ray diffraction analysis and phasing of a Fab fragment of monoclonal neuroantibody alphaD11 against nerve growth factor.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 7):1323-7.
2003: Enrico Garaci; Stefano Aquaro; Caterina Lapenta; Alessandra Amendola; Massimo Spada; Sonia Covaceuszach; Carlo Federico Perno; Filippo Belardelli
Anti-nerve growth factor Ab abrogates macrophage-mediated HIV-1 infection and depletion of CD4+ T lymphocytes in hu-SCID mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8927-32.
2002: Elisa Margotti; Sonia Covaceuszach; Enrico Tongiorgi; Antonino Cattaneo; Luciano Domenici
TRKB signalling controls the expression of N-methyl-d-aspartate receptors in the visual cortex.
The European journal of neuroscience 2002;16(6):1067-74.
2002: Daniela Tropea; Simona Capsoni; Sonia Covaceuszach; Luciano Domenici; Antonino Cattaneo
Rat visual cortical neurones express TrkA NGF receptor.
Neuroreport 2002;13(10):1369-73.
2001: Sonia Covaceuszach; Antonino Cattaneo; Doriano Lamba
Purification, crystallization and preliminary X-ray analysis of the Fab fragment from MNAC13, a novel antagonistic anti-tyrosine kinase A receptor monoclonal antibody.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 9):1307-9.