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Philip Cowen
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41
Harmer, Catherine
22
Goodwin, Guy
17
Bhagwagar, Zubin
14
Sargent, Peter
11
Campling, G
11
McTavish, Sarah
10
Grasby, Paul
9
Whale, Richard
9
Sharp, Trevor
7
Sharpley, Ann
7
Rabiner, Eugenii
7
Hafizi, Sepehr
7
Franklin, Mike
7
Mannie, Zola
6
Harrison, Paul
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All Publications
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2009: Taylor Matthew J; Selvaraj Sudhakar; Norbury Ray; Jezzard Peter; Cowen Philip J
Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patients.
Journal of affective disorders 2009;119(1-3):186-9.
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2009: Miskowiak Kamilla W; Favaron Elisa; Hafizi Sepehr; Inkster Becky; Goodwin Guy M; Cowen Philip J; Harmer Catherine J
Effects of erythropoietin on emotional processing biases in patients with major depression: an exploratory fMRI study.
Psychopharmacology 2009;207(1):133-42.
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2009: Malcolm C P; Cowen P J; Harmer C J
High-density negative ion treatment increases positive affective memory.
Psychological medicine 2009;39(11):1930-2.
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2009: Harmer Catherine J; O'Sullivan Ursula; Favaron Elisa; Massey-Chase Rachel; Ayres Rachael; Reinecke Andrea; Goodwin Guy M; Cowen Philip J
Effect of acute antidepressant administration on negative affective bias in depressed patients.
The American journal of psychiatry 2009;166(10):1178-84.
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2009: Norbury Ray; Taylor Matthew J; Selvaraj Sudhakar; Murphy Susannah E; Harmer Catherine J; Cowen Philip J
Short-term antidepressant treatment modulates amygdala response to happy faces.
Psychopharmacology 2009;206(2):197-204.
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2009: McCabe Ciara; Cowen Philip J; Harmer Catherine J
NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009;12(9):1261-74.
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2009: McCabe Ciara; Cowen Philip J; Harmer Catherine J
Neural representation of reward in recovered depressed patients.
Psychopharmacology 2009;205(4):667-77.
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2009: Murphy Susannah E; Longhitano Carlo; Ayres Rachael E; Cowen Philip J; Harmer Catherine J; Rogers Robert D
The role of serotonin in nonnormative risky choice: the effects of tryptophan supplements on the "reflection effect" in healthy adult volunteers.
Journal of cognitive neuroscience 2009;21(9):1709-19.
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2009: Harmer Catherine J; Goodwin Guy M; Cowen Philip J
Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action.
The British journal of psychiatry : the journal of mental science 2009;195(2):102-8.
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2009: Horder Jamie; Cowen Philip J; Di Simplicio Martina; Browning Michael; Harmer Catherine J
Acute administration of the cannabinoid CB1 antagonist rimonabant impairs positive affective memory in healthy volunteers.
Psychopharmacology 2009;205(1):85-91.
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2009: Murphy Susannah E; Norbury Raymond; O'Sullivan Ursula; Cowen Philip J; Harmer Catherine J
Effect of a single dose of citalopram on amygdala response to emotional faces.
The British journal of psychiatry : the journal of mental science 2009;194(6):535-40.
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2009: Arnone D; Horder J; Cowen P J; Harmer C J
Early effects of mirtazapine on emotional processing.
Psychopharmacology 2009;203(4):685-91.
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2009: Mannie Z N; Barnes J; Bristow G C; Harmer C J; Cowen P J
Memory impairment in young women at increased risk of depression: influence of cortisol and 5-HTT genotype.
Psychological medicine 2009;39(5):757-62.
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2009: Murphy Susannah E; Yiend Jenny; Lester Kathryn J; Cowen Philip J; Harmer Catherine J
Short-term serotonergic but not noradrenergic antidepressant administration reduces attentional vigilance to threat in healthy volunteers.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009;12(2):169-79.
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2008: Norbury R; Mackay C E; Cowen P J; Goodwin G M; Harmer C J
The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study.
Molecular psychiatry 2008;13(11):1011-20.
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2008: Murphy S E; Downham C; Cowen P J; Harmer C J
Direct effects of diazepam on emotional processing in healthy volunteers.
Psychopharmacology 2008;199(4):503-13.
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2008: Harmer C J; Heinzen J; O'Sullivan U; Ayres R A; Cowen P J
Dissociable effects of acute antidepressant drug administration on subjective and emotional processing measures in healthy volunteers.
Psychopharmacology 2008;199(4):495-502.
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2008: Mannie Zola N; Norbury Ray; Murphy Susannah E; Inkster Becky; Harmer Catherine J; Cowen Philip J
Affective modulation of anterior cingulate cortex in young people at increased familial risk of depression.
The British journal of psychiatry : the journal of mental science 2008;192(5):356-61.
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2007: Munafò Marcus R; Mannie Zola N; Cowen Philip J; Harmer Catherine J; McTavish Sarah B
Effects of acute tyrosine depletion on subjective craving and selective processing of smoking-related cues in abstinent cigarette smokers.
Journal of psychopharmacology (Oxford, England) 2007;21(8):805-14.
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2007: Mannie Zola N; Bristow Greg C; Harmer Catherine J; Cowen Philip J
Impaired emotional categorisation in young people at increased familial risk of depression.
Neuropsychologia 2007;45(13):2975-80.
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2007: Miskowiak Kamilla; Papadatou-Pastou Marietta; Cowen Philip J; Goodwin Guy M; Norbury Ray; Harmer Catherine J
Single dose antidepressant administration modulates the neural processing of self-referent personality trait words.
NeuroImage 2007;37(3):904-11.
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2007: Browning M; Reid C; Cowen P J; Goodwin G M; Harmer C J
A single dose of citalopram increases fear recognition in healthy subjects.
Journal of psychopharmacology (Oxford, England) 2007;21(7):684-90.
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2007: Scrutton Helen; Carbonnier Anne; Cowen Philip J; Harmer Catherine J
Effects of alpha-lactalbumin on emotional processing in healthy women.
Journal of psychopharmacology (Oxford, England) 2007;21(5):519-24.
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2007: Norbury Ray; Mackay Clare E; Cowen Philip J; Goodwin Guy M; Harmer Catherine J
Short-term antidepressant treatment and facial processing. Functional magnetic resonance imaging study.
The British journal of psychiatry : the journal of mental science 2007;190():531-2.
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2007: Mannie Zola N; Harmer Catherine J; Cowen Philip J
Increased waking salivary cortisol levels in young people at familial risk of depression.
The American journal of psychiatry 2007;164(4):617-21.
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2007: Bhagwagar Zubin; Wylezinska Marzena; Jezzard Peter; Evans John; Ashworth Fiona; Sule Akeem; Matthews Paul M; Cowen Philip J
Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects.
Biological psychiatry 2007;61(6):806-12.
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2007: Le Masurier Marisa; Cowen Philip J; Harmer Catherine J
Emotional bias and waking salivary cortisol in relatives of patients with major depression.
Psychological medicine 2007;37(3):403-10.
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2006: Selvaraj S; Wylezinska M; Evans J; Jezzard P; Matthews P M; Cowen P J
Tryptophan depletion does not lower brain GABA levels in healthy volunteers.
Psychopharmacology 2006;187(1):131-2.
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2006: Murphy Susannah E; Longhitano Calogero; Ayres Rachael E; Cowen Philip J; Harmer Catherine J
Tryptophan supplementation induces a positive bias in the processing of emotional material in healthy female volunteers.
Psychopharmacology 2006;187(1):121-30.
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2006: Harmer Catherine J; Reid Catriona B; Ray Manaan Kar; Goodwin Guy M; Cowen Philip J
5HT(3) antagonism abolishes the emotion potentiated startle effect in humans.
Psychopharmacology 2006;186(1):18-24.
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2006: Le Masurier Marisa; Oldenzeil Weite; Lehman Claire; Cowen Philip; Sharp Trevor
Effect of acute tyrosine depletion in using a branched chain amino-acid mixture on dopamine neurotransmission in the rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(2):310-7.
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2005: Bhagwagar Zubin; Hafizi Sepehr; Cowen Philip J
Increased salivary cortisol after waking in depression.
Psychopharmacology 2005;182(1):54-7.
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2005: Scarnà A; McTavish S F B; Cowen P J; Goodwin G M; Rogers R D
The effects of a branched chain amino acid mixture supplemented with tryptophan on biochemical indices of neurotransmitter function and decision-making.
Psychopharmacology 2005;179(4):761-8.
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2005: Cowen Philip J
Fluoxetine improves minor depressive disorders.
Evidence-based mental health 2005;8(2):36.
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2005: Sharpley Ann L; Attenburrow Mary E J; Hafizi Sepehr; Cowen Philip J
Olanzapine increases slow wave sleep and sleep continuity in SSRI-resistant depressed patients.
The Journal of clinical psychiatry 2005;66(4):450-4.
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2005: Portella Maria J; Harmer Catherine J; Flint Jonathan; Cowen Philip; Goodwin Guy M
Enhanced early morning salivary cortisol in neuroticism.
The American journal of psychiatry 2005;162(4):807-9.
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2005: McTavish Sarah F B; Mannie Zola N; Harmer Catherine J; Cowen Philip J
Lack of effect of tyrosine depletion on mood in recovered depressed women.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(4):786-91.
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2005: Cowen Philip J; Ogilvie Alan D; Gama Joubert
Efficacy, safety and tolerability of duloxetine 60 mg once daily in major depression.
Current medical research and opinion 2005;21(3):345-56.
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2005: Hayward Gail; Goodwin Guy M; Cowen Phil J; Harmer Catherine J
Low-dose tryptophan depletion in recovered depressed patients induces changes in cognitive processing without depressive symptoms.
Biological psychiatry 2005;57(5):517-24.
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2004: Völlm Birgit A; de Araujo Ivan E; Cowen Philip J; Rolls Edmund T; Kringelbach Morten L; Smith Katharine A; Jezzard Peter; Heal Ronald J; Matthews Paul M
Methamphetamine activates reward circuitry in drug naïve human subjects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(9):1715-22.
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2004: Nadeem Haitham S; Attenburrow Mary-Jane; Cowen Philip J
Comparison of the effects of citalopram and escitalopram on 5-Ht-mediated neuroendocrine responses.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(9):1699-703.
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2004: Rabiner Eugenii A; Bhagwagar Zubin; Gunn Roger N; Cowen Philip J; Grasby Paul M
Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(9):1688-98.
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2004: McTavish S F B; Mannie Z N; Cowen P J
Tyrosine depletion does not cause depressive relapse in antidepressant-treated patients.
Psychopharmacology 2004;175(1):124-6.
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2004: Harmer Catherine J; Shelley Nicholas C; Cowen Philip J; Goodwin Guy M
Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition.
The American journal of psychiatry 2004;161(7):1256-63.
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2004: Pooley Edward C; Fairburn Christopher G; Cooper Zafra; Sodhi Monsheel S; Cowen Philip J; Harrison Paul J
A 5-HT2C receptor promoter polymorphism (HTR2C - 759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;126B(1):124-7.
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2004: Bhagwagar Z; Rabiner E A; Sargent P A; Grasby P M; Cowen P J
Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635.
Molecular psychiatry 2004;9(4):386-92.
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2004: Bhagwagar Zubin; Wylezinska Marzena; Taylor Matthew; Jezzard Peter; Matthews Paul M; Cowen Philip J
Increased brain GABA concentrations following acute administration of a selective serotonin reuptake inhibitor.
The American journal of psychiatry 2004;161(2):368-70.
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2004: Le Masurier Marisa; Cowen Philip J; Sharp Trevor
Fos immunocytochemical studies on the neuroanatomical sites of action of acute tyrosine depletion in the rat brain.
Psychopharmacology 2004;171(4):435-40.
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2004: Le Masurier Marisa; Houston Gavin; Cowen Philip; Grasby Paul; Sharp Trevor; Hume Susan
Tyrosine-free amino acid mixture attenuates amphetamine-induced displacement of [11C]raclopride in striatum in vivo: a rat PET study.
Synapse (New York, N.Y.) 2004;51(2):151-7.
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2004: Bhagwagar Zubin; Cowen Philip J; Goodwin Guy M; Harmer Catherine J
Normalization of enhanced fear recognition by acute SSRI treatment in subjects with a previous history of depression.
The American journal of psychiatry 2004;161(1):166-8.
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2003: Attenburrow M J; Williams C; Odontiadis J; Powell J; Van de Ouderaa F; Williams M; Cowen P J
The effect of a nutritional source of tryptophan on dieting-induced changes in brain 5-HT function.
Psychological medicine 2003;33(8):1381-6.
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2003: Bhagwagar Zubin; Montgomery Andrew J; Grasby Paul M; Cowen Philip J
Lack of effect of a single dose of hydrocortisone on serotonin(1A) receptors in recovered depressed patients measured by positron emission tomography with [11C]WAY-100635.
Biological psychiatry 2003;54(9):890-5.
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2003: Bhagwagar Zubin; Hafizi Sepehr; Cowen Philip J
Increase in concentration of waking salivary cortisol in recovered patients with depression.
The American journal of psychiatry 2003;160(10):1890-1.
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2003: Montgomery Andrew J; McTavish Sarah F B; Cowen Philip J; Grasby Paul M
Reduction of brain dopamine concentration with dietary tyrosine plus phenylalanine depletion: an [11C]raclopride PET study.
The American journal of psychiatry 2003;160(10):1887-9.
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2003: Hill S A; Taylor M J; Harmer C J; Cowen P J
Acute reboxetine administration increases plasma and salivary cortisol.
Journal of psychopharmacology (Oxford, England) 2003;17(3):273-5.
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2003: Attenburrow M-J; Williams C; Odontiadis J; Reed A; Powell J; Cowen P J; Harmer C J
Acute administration of nutritionally sourced tryptophan increases fear recognition.
Psychopharmacology 2003;169(1):104-7.
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2003: Harmer C J; Rogers R D; Tunbridge E; Cowen P J; Goodwin G M
Tryptophan depletion decreases the recognition of fear in female volunteers.
Psychopharmacology 2003;167(4):411-7.
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2003: Harmer Catherine J; Hill Simon A; Taylor Matthew J; Cowen Philip J; Goodwin Guy M
Toward a neuropsychological theory of antidepressant drug action: increase in positive emotional bias after potentiation of norepinephrine activity.
The American journal of psychiatry 2003;160(5):990-2.
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2003: Harmer C J; Bhagwagar Z; Shelley N; Cowen P J
Contrasting effects of citalopram and reboxetine on waking salivary cortisol.
Psychopharmacology 2003;167(1):112-4.
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2003: Scarna A; Gijsman H J; McTavish S F B; Harmer C J; Cowen P J; Goodwin G M
Effects of a branched-chain amino acid drink in mania.
The British journal of psychiatry : the journal of mental science 2003;182():210-3.
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2003: Sharpley Ann L; Bhagwagar Zubin; Hafizi Sepehr; Whale W Richard; Gijsman Harm J; Cowen Philip J
Risperidone augmentation decreases rapid eye movement sleep and decreases wake in treatment-resistant depressed patients.
The Journal of clinical psychiatry 2003;64(2):192-6.
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2002: Bhagwagar Zubin; Hafizi Sepehr; Cowen P J
Cortisol modulation of 5-HT-mediated growth hormone release in recovered depressed patients.
Journal of affective disorders 2002;72(3):249-55.
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2002: Smith K A; Ploghaus A; Cowen P J; McCleery J M; Goodwin G M; Smith S; Tracey I; Matthews P M
Cerebellar responses during anticipation of noxious stimuli in subjects recovered from depression. Functional magnetic resonance imaging study.
The British journal of psychiatry : the journal of mental science 2002;181():411-5.
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2002: Bhagwagar Z; Hafizi S; Cowen P J
Acute citalopram administration produces correlated increases in plasma and salivary cortisol.
Psychopharmacology 2002;163(1):118-20.
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2002: Gijsman Harm J; Scarnà Antonina; Harmer Catherine J; McTavish Sarah B; Odontiadis John; Cowen Philip J; Goodwin Guy M
A dose-finding study on the effects of branch chain amino acids on surrogate markers of brain dopamine function.
Psychopharmacology 2002;160(2):192-7.
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2002: Rabiner Eugenii A; Messa Cristina; Sargent Peter A; Husted-Kjaer Karen; Montgomery Andrew; Lawrence Andrew D; Bench Christopher J; Gunn Roger N; Cowen Phillip; Grasby Paul M
A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables.
NeuroImage 2002;15(3):620-32.
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2002: Attenburrow M-J; Odontiadis J; Murray B J; Cowen P J; Franklin M
Chromium treatment decreases the sensitivity of 5-HT2A receptors.
Psychopharmacology 2002;159(4):432-6.
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2002: Scarnà Antonina; Gijsman Harm J; Harmer Catherine J; Goodwin Guy M; Cowen Philip J
Effect of branch chain amino acids supplemented with tryptophan on tyrosine availability and plasma prolactin.
Psychopharmacology 2002;159(2):222-3.
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2002: Bhagwagar Zubin; Whale Richard; Cowen Philip J
State and trait abnormalities in serotonin function in major depression.
The British journal of psychiatry : the journal of mental science 2002;180():24-8.
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2001: Rabiner E A; Bhagwagar Z; Gunn R N; Sargent P A; Bench C J; Cowen P J; Grasby P M
Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials is too low.
The American journal of psychiatry 2001;158(12):2080-2.
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2001: McTavish S F; McPherson M H; Harmer C J; Clark L; Sharp T; Goodwin G M; Cowen P J
Antidopaminergic effects of dietary tyrosine depletion in healthy subjects and patients with manic illness.
The British journal of psychiatry : the journal of mental science 2001;179():356-60.
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2001: Murray B J; Cowen P J; Sharpley A L
The effect of Li 1370, extract of Ginkgo biloba, on REM sleep in humans.
Pharmacopsychiatry 2001;34(4):155-7.
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2001: Franklin M; Cowen P J
Effect of a low tryptophan diet on the prolactin responses to the 5-HT2A agonist DOI in the rat.
Pharmacopsychiatry 2001;34(4):147-9.
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2001: Franklin M; Cowen P J
Researching the antidepressant actions of Hypericum perforatum (St. John's wort) in animals and man.
Pharmacopsychiatry 2001;34 Suppl 1():S29-37.
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2001: McTavish S F; Raumann B; Cowen P J; Sharp T
Tyrosine depletion attenuates the behavioural stimulant effects of amphetamine and cocaine in rats.
European journal of pharmacology 2001;424(2):115-9.
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2001: Attenburrow M J; Mitter P R; Whale R; Terao T; Cowen P J
Low-dose citalopram as a 5-HT neuroendocrine probe.
Psychopharmacology 2001;155(3):323-6.
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2001: Vassallo C M; Feldman E; Peto T; Castell L; Sharpley A L; Cowen P J
Decreased tryptophan availability but normal post-synaptic 5-HT2c receptor sensitivity in chronic fatigue syndrome.
Psychological medicine 2001;31(4):585-91.
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2001: Whale R; Clifford E M; Bhagwagar Z; Cowen P J
Decreased sensitivity of 5-HT(1D) receptors in melancholic depression.
The British journal of psychiatry : the journal of mental science 2001;178():454-7.
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2001: Harmer C J; Perrett D I; Cowen P J; Goodwin G M
Administration of the beta-adrenoceptor blocker propranolol impairs the processing of facial expressions of sadness.
Psychopharmacology 2001;154(4):383-9.
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2001: Harmer C J; McTavish S F; Clark L; Goodwin G M; Cowen P J
Tyrosine depletion attenuates dopamine function in healthy volunteers.
Psychopharmacology 2001;154(1):105-11.
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2001: Sharpley A L; Vassallo C M; Pooley E C; Harrison P J; Cowen P J
Allelic variation in the 5-HT2C receptor (HT2RC) and the increase in slow wave sleep produced by olanzapine.
Psychopharmacology 2001;153(2):271-2.
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2000: Rabiner E A; Gunn R N; Castro M E; Sargent P A; Cowen P J; Koepp M J; Meyer J H; Bench C J; Harrison P J; Pazos A; Sharp T; Grasby P M
beta-blocker binding to human 5-HT(1A) receptors in vivo and in vitro: implications for antidepressant therapy.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(3):285-93.
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2000: Rabiner E A; Gunn R N; Wilkins M R; Sargent P A; Mocaer E; Sedman E; Cowen P J; Grasby P M
Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635.
Nuclear medicine and biology 2000;27(5):509-13.
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2000: Cowen P J
Psychopharmacology of 5-HT(1A) receptors.
Nuclear medicine and biology 2000;27(5):437-9.
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2000: Whale R; Quested D J; Laver D; Harrison P J; Cowen P J
Serotonin transporter (5-HTT) promoter genotype may influence the prolactin response to clomipramine.
Psychopharmacology 2000;150(1):120-2.
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2000: Sharpley A L; Vassallo C M; Cowen P J
Olanzapine increases slow-wave sleep: evidence for blockade of central 5-HT(2C) receptors in vivo.
Biological psychiatry 2000;47(5):468-70.
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2000: Whale R; Clifford E M; Cowen P J
Does mirtazapine enhance serotonergic neurotransmission in depressed patients?
Psychopharmacology 2000;148(3):325-6.
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2000: Sargent P A; Kjaer K H; Bench C J; Rabiner E A; Messa C; Meyer J; Gunn R N; Grasby P M; Cowen P J
Brain serotonin1A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment.
Archives of general psychiatry 2000;57(2):174-80.
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2000: Smith K A; Williams C; Cowen P J
Impaired regulation of brain serotonin function during dieting in women recovered from depression.
The British journal of psychiatry : the journal of mental science 2000;176():72-5.
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2000: McCleery J M; Bhagwagar Z; Smith K A; Goodwin G M; Cowen P J
Modelling a loss event: effect of imagined bereavement on the hypothalamic-pituitary-adrenal axis.
Psychological medicine 2000;30(1):219-23.
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2000: Franklin M; Chi J D; Mannel M; Cowen P J
Acute effects of LI 160 (extract of Hypericum perforatum, St John's wort) and two of its constituents on neuroendocrine responses in the rat.
Journal of psychopharmacology (Oxford, England) 2000;14(4):360-3.
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1999: McTavish S F; Callado L; Cowen P J; Sharp T
Comparison of the effects of alpha-methyl-p-tyrosine and a tyrosine-free amino acid load on extracellular noradrenaline in the rat hippocampus in vivo.
Journal of psychopharmacology (Oxford, England) 1999;13(4):379-84.
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1999: Fairburn C G; Cowen P J; Harrison P J
Twin studies and the etiology of eating disorders.
The International journal of eating disorders 1999;26(4):349-58.
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1999: Franklin M; Chi J; McGavin C; Hockney R; Reed A; Campling G; Whale R W; Cowen P J
Neuroendocrine evidence for dopaminergic actions of hypericum extract (LI 160) in healthy volunteers.
Biological psychiatry 1999;46(4):581-4.
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1999: Whale R; Bhagwagar Z; Cowen P J
Zolmitriptan-induced growth hormone release in humans: mediation by 5-HT1D receptors?
Psychopharmacology 1999;145(2):223-6.
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1999: Smith K A; Morris J S; Friston K J; Cowen P J; Dolan R J
Brain mechanisms associated with depressive relapse and associated cognitive impairment following acute tryptophan depletion.
The British journal of psychiatry : the journal of mental science 1999;174():525-9.
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1999: Quested D J; Whale R; Sharpley A L; McGavin C L; Crossland N; Harrison P J; Cowen P J
Allelic variation in the 5-HT2C receptor (HTR2C) and functional responses to the 5-HT2C receptor agonist, m-chlorophenylpiperazine.
Psychopharmacology 1999;144(3):306-7.
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1999: Burnet P W; Smith K A; Cowen P J; Fairburn C G; Harrison P J
Allelic variation of the 5-HT2C receptor (HTR2C) in bulimia nervosa and binge eating disorder.
Psychiatric genetics 1999;9(2):101-4.
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1999: Smith K A; Fairburn C G; Cowen P J
Symptomatic relapse in bulimia nervosa following acute tryptophan depletion.
Archives of general psychiatry 1999;56(2):171-6.
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1999: McTavish S F; Cowen P J; Sharp T
Effect of a tyrosine-free amino acid mixture on regional brain catecholamine synthesis and release.
Psychopharmacology 1999;141(2):182-8.
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1999: Cowen P J; Smith K A
Serotonin, dieting, and bulimia nervosa.
Advances in experimental medicine and biology 1999;467():101-4.
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1999: McTavish S F; McPherson M H; Sharp T; Cowen P J
Attenuation of some subjective effects of amphetamine following tyrosine depletion.
Journal of psychopharmacology (Oxford, England) 1999;13(2):144-7.
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1999: Franklin M; Craven R D; Dowling B; Campling G; Elliott J M; Cowen P J
Effect of a long-term low tryptophan diet on the prolactin responses to the 5-HT1A and 5-HT2C agonists, 8-OH-DPAT and mCPP in the male rat.
Journal of psychopharmacology (Oxford, England) 1999;13(1):58-63.
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1998: Sargent P A; Quested D J; Cowen P J
Clomipramine enhances the cortisol response to 5-HTP: implications for the therapeutic role of 5-HT2 receptors.
Psychopharmacology 1998;140(1):120-2.
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1998: Sharpley A L; McGavin C L; Whale R; Cowen P J
Antidepressant-like effect of Hypericum perforatum (St John's wort) on the sleep polysomnogram.
Psychopharmacology 1998;139(3):286-7.
-
1998: Williams J H; Wellman N A; Geaney D P; Cowen P J; Feldon J; Rawlins J N
Reduced latent inhibition in people with schizophrenia: an effect of psychosis or of its treatment.
The British journal of psychiatry : the journal of mental science 1998;172():243-9.
-
1998: Young A H; Rue J; Odontiadis J; Cowen P J
Lack of effect of hydrocortisone treatment on d-fenfluramine-mediated prolactin release.
Psychopharmacology 1998;136(2):198-200.
-
1998: Young A H; Sharpe M; Clements A; Dowling B; Hawton K E; Cowen P J
Basal activity of the hypothalamic-pituitary-adrenal axis in patients with the chronic fatigue syndrome (neurasthenia).
Biological psychiatry 1998;43(3):236-7.
-
1998: Sargent P A; Williamson D J; Cowen P J
Brain 5-HT neurotransmission during paroxetine treatment.
The British journal of psychiatry : the journal of mental science 1998;172():49-52.
-
1998: Franklin M; Clement E M; Campling G; Cowen P J
Effect of venlafaxine on pineal melatonin and noradrenaline in the male rat.
Journal of psychopharmacology (Oxford, England) 1998;12(4):371-4.
-
1997: Sargent P A; Sharpley A L; Williams C; Goodall E M; Cowen P J
5-HT2C receptor activation decreases appetite and body weight in obese subjects.
Psychopharmacology 1997;133(3):309-12.
-
1997: Quested D J; Sargent P A; Cowen P J
SSRI treatment decreases prolactin and hyperthermic responses to mCPP.
Psychopharmacology 1997;133(3):305-8.
-
1997: Williams J H; Wellman N A; Geaney D P; Feldon J; Cowen P J; Rawlins J N
Haloperidol enhances latent inhibition in visual tasks in healthy people.
Psychopharmacology 1997;133(3):262-8.
-
1997: Sargent P; Williamson D J; Pearson G; Odontiadis J; Cowen P J
Effect of paroxetine and nefazodone on 5-HT1A receptor sensitivity.
Psychopharmacology 1997;132(3):296-302.
-
1997: Sharpe M; Hawton K; Clements A; Cowen P J
Increased brain serotonin function in men with chronic fatigue syndrome.
BMJ (Clinical research ed.) 1997;315(7101):164-5.
-
1997: Smith K A; Fairburn C G; Cowen P J
Relapse of depression after rapid depletion of tryptophan.
Lancet 1997;349(9056):915-9.
-
1997: Boeles S; Williams C; Campling G M; Goodall E M; Cowen P J
Sumatriptan decreases food intake and increases plasma growth hormone in healthy women.
Psychopharmacology 1997;129(2):179-82.
-
1997: Cowen P J; Sargent P A
Changes in plasma prolactin during SSRI treatment: evidence for a delayed increase in 5-HT neurotransmission.
Journal of psychopharmacology (Oxford, England) 1997;11(4):345-8.
-
1997: Williams J H; Wellman N A; Geaney D P; Rawlins J N; Feldon J; Cowen P J
Intravenous administration of haloperidol to healthy volunteers: lack of subjective effects but clear objective effects.
Journal of psychopharmacology (Oxford, England) 1997;11(3):247-52.
-
1996: Williams J H; Wellman N A; Geaney D P; Cowen P J; Feldon J; Rawlins J N
Antipsychotic drug effects in a model of schizophrenic attentional disorder: a randomized controlled trial of the effects of haloperidol on latent inhibition in healthy people.
Biological psychiatry 1996;40(11):1135-43.
-
1996: Sharpe M; Clements A; Hawton K; Young A H; Sargent P; Cowen P J
Increased prolactin response to buspirone in chronic fatigue syndrome.
Journal of affective disorders 1996;41(1):71-6.
-
1996: Park S B; Williamson D J; Cowen P J
5-HT neuroendocrine function in major depression: prolactin and cortisol responses to D-fenfluramine.
Psychological medicine 1996;26(6):1191-6.
-
1996: Cowen P J; Clifford E M; Walsh A E; Williams C; Fairburn C G
Moderate dieting causes 5-HT2C receptor supersensitivity.
Psychological medicine 1996;26(6):1155-9.
-
1996: Attenburrow M E; Cowen P J; Sharpley A L
Low dose melatonin improves sleep in healthy middle-aged subjects.
Psychopharmacology 1996;126(2):179-81.
-
1996: Sharpley A L; Williamson D J; Attenburrow M E; Pearson G; Sargent P; Cowen P J
The effects of paroxetine and nefazodone on sleep: a placebo controlled trial.
Psychopharmacology 1996;126(1):50-4.
-
1996: Johnson B A; Oldman D; Goodall E M; Chen Y R; Cowen P J
Effects of GR 68755 on d-amphetamine-induced changes in mood, cognitive performance, appetite, food preference, and caloric and macronutrient intake in humans.
Behavioural pharmacology 1996;7(3):216-27.
-
1996: Attenburrow M E; Dowling B A; Sharpley A L; Cowen P J
Case-control study of evening melatonin concentration in primary insomnia.
BMJ (Clinical research ed.) 1996;312(7041):1263-4.
-
1996: Wing Y K; Clifford E M; Sheehan B D; Campling G M; Hockney R A; Cowen P J
Paroxetine treatment and the prolactin response to sumatriptan.
Psychopharmacology 1996;124(4):377-9.
-
1996: Delva N J; Matthews D R; Cowen P J
Brain serotonin (5-HT) neuroendocrine function in patients taking cholesterol-lowering drugs.
Biological psychiatry 1996;39(2):100-6.
-
1996: Cowen P J; Williamson D J; McTavish S F
Effect of valine on 5-HT neurotransmission and mood.
Advances in experimental medicine and biology 1996;398():67-71.
-
1995: Park S B; Williamson D J; Cowen P J
Do the endocrine and subjective effects of d-fenfluramine predict response to selective serotonin reuptake inhibitors?
International clinical psychopharmacology 1995;10(4):215-20.
-
1995: Attenburrow M E; Dowling B A; Sargent P A; Sharpley A L; Cowen P J
Melatonin phase advances circadian rhythm.
Psychopharmacology 1995;121(4):503-5.
-
1995: Oldman A; Walsh A; Salkovskis P; Fairburn C G; Cowen P J
Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study.
Psychological medicine 1995;25(5):995-1001.
-
1995: Coull J T; Sahakian B J; Middleton H C; Young A H; Park S B; McShane R H; Cowen P J; Robbins T W
Differential effects of clonidine, haloperidol, diazepam and tryptophan depletion on focused attention and attentional search.
Psychopharmacology 1995;121(2):222-30.
-
1995: Cowen P J; Clifford E M; Williams C; Walsh A E; Fairburn C G
Why is dieting so difficult.
Nature 1995;376(6541):557.
-
1995: Williamson D J; McTavish S F; Park S B; Cowen P J
Effect of valine on 5-HT-mediated prolactin release in healthy volunteers, and on mood in remitted depressed patients.
The British journal of psychiatry : the journal of mental science 1995;167(2):238-42.
-
1995: Park S B; Cowen P J
Effect of pindolol on the prolactin response to d-fenfluramine.
Psychopharmacology 1995;118(4):471-4.
-
1995: Walsh A E; Oldman A D; Franklin M; Fairburn C G; Cowen P J
Dieting decreases plasma tryptophan and increases the prolactin response to d-fenfluramine in women but not men.
Journal of affective disorders 1995;33(2):89-97.
-
1995: Sharpley A L; Cowen P J
Effect of pharmacologic treatments on the sleep of depressed patients.
Biological psychiatry 1995;37(2):85-98.
-
1994: Young A H; Sharpley A L; Campling G M; Hockney R A; Cowen P J
Effects of hydrocortisone on brain 5-HT function and sleep.
Journal of affective disorders 1994;32(2):139-46.
-
1994: Silverstone P H; Cowen P J
The 5-HT3 antagonist, BRL 46470 does not attenuate m-chlorophenylpiperazine (mCPP)-induced changes in human volunteers.
Biological psychiatry 1994;36(5):309-16.
-
1994: Walsh A E; Smith K A; Oldman A D; Williams C; Goodall E M; Cowen P J
m-Chlorophenylpiperazine decreases food intake in a test meal.
Psychopharmacology 1994;116(1):120-2.
-
1994: Silverstone P H; Rue J E; Franklin M; Hallis K; Camplin G; Laver D; Cowen P J
The effects of administration of mCPP on psychological, cognitive, cardiovascular, hormonal and MHPG measurements in human volunteers.
International clinical psychopharmacology 1994;9(3):173-8.
-
1994: Walsh A E; Cowen P J
Attenuation of the prolactin-stimulating and hyperthermic effects of nefazodone after subacute treatment.
Journal of clinical psychopharmacology 1994;14(4):268-73.
-
1994: Cowen P J; Power A C; Ware C J; Anderson I M
5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone.
The British journal of psychiatry : the journal of mental science 1994;164(3):372-9.
-
1994: Park S B; Coull J T; McShane R H; Young A H; Sahakian B J; Robbins T W; Cowen P J
Tryptophan depletion in normal volunteers produces selective impairments in learning and memory.
Neuropharmacology 1994;33(3-4):575-88.
-
1994: Sharpley A L; Elliott J M; Attenburrow M J; Cowen P J
Slow wave sleep in humans: role of 5-HT2A and 5-HT2C receptors.
Neuropharmacology 1994;33(3-4):467-71.
-
1994: Herdman J R; Delva N J; Hockney R E; Campling G M; Cowen P J
Neuroendocrine effects of sumatriptan.
Psychopharmacology 1994;113(3-4):561-4.
-
1993: Young A H; McShane R; Park S B; Cowen P J
Buspirone-induced hypothermia in normal male volunteers.
Biological psychiatry 1993;34(9):665-6.
-
1993: Herdman J R; Cowen P J; Campling G M; Hockney R A; Laver D; Sharpley A L
Effect of lofepramine on 5-HT function and sleep.
Journal of affective disorders 1993;29(1):63-72.
-
1993: Power A C; Dorkins C E; Cowen P J
Effect of lithium on the prolactin response to D-fenfluramine in healthy subjects.
Biological psychiatry 1993;33(11-12):801-5.
-
1993: Morriss R; Sharpe M; Sharpley A L; Cowen P J; Hawton K; Morris J
Abnormalities of sleep in patients with the chronic fatigue syndrome.
BMJ (Clinical research ed.) 1993;306(6886):1161-4.
-
1993: Katsuda Y; Walsh A E; Ware C J; Cowen P J; Sharpley A L
meta-Chlorophenylpiperazine decreases slow-wave sleep in humans.
Biological psychiatry 1993;33(1):49-51.
-
1993: Walsh A E; Hockney R A; Campling G; Cowen P J
Neuroendocrine and temperature effects of nefazodone in healthy volunteers.
Biological psychiatry 1993;33(2):115-9.
-
1993: Cowen P J
Serotonin receptor subtypes in depression: evidence from studies in neuroendocrine regulation.
Clinical neuropharmacology 1993;16 Suppl 3():S6-18.
-
1993: Johnson B A; Rue J; Cowen P J
Ondansetron and alcohol pharmacokinetics.
Psychopharmacology 1993;112(1):145.
-
1993: Johnson B A; Campling G M; Griffiths P; Cowen P J
Attenuation of some alcohol-induced mood changes and the desire to drink by 5-HT3 receptor blockade: a preliminary study in healthy male volunteers.
Psychopharmacology 1993;112(1):142-4.
-
1992: Power A C; Cowen P J
Fluoxetine and suicidal behaviour. Some clinical and theoretical aspects of a controversy.
The British journal of psychiatry : the journal of mental science 1992;161():735-41.
-
1992: Gartside S E; Ellis P M; Sharp T; Cowen P J
Selective 5-HT1A and 5-HT2 receptor-mediated adrenocorticotropin release in the rat: effect of repeated antidepressant treatments.
European journal of pharmacology 1992;221(1):27-33.
-
1992: Geaney D P; Ellis P M; Soper N; Shepstone B J; Cowen P J
Single photon emission tomography assessment of cerebral dopamine D2 receptor blockade in schizophrenia.
Biological psychiatry 1992;32(3):293-5.
-
1992: Sharpley A L; Walsh A E; Cowen P J
Nefazodone--a novel antidepressant--may increase REM sleep.
Biological psychiatry 1992;31(10):1070-3.
-
1992: Glue P; Wilson S; Campling G M; Knightly M; Franklin M; Cowen P J; Nutt D J
Alpha-2-adrenoceptor control of cortisol and ACTH in normal volunteers: preliminary open trial of the effects of acute and chronic idazoxan.
Psychoneuroendocrinology 1992;17(2-3):261-6.
-
1992: da Roza Davis J M; Sharpley A L; Solomon R A; Cowen P J
Sleep and 5-HT2 receptor sensitivity in recovered depressed patients.
Journal of affective disorders 1992;24(3):177-81.
-
1992: Anderson I M; Ware C J; da Roza Davis J M; Cowen P J
Decreased 5-HT-mediated prolactin release in major depression.
The British journal of psychiatry : the journal of mental science 1992;160():372-8.
-
1992: Anderson I M; Cowen P J
Effect of pindolol on endocrine and temperature responses to buspirone in healthy volunteers.
Psychopharmacology 1992;106(3):428-32.
-
1992: Silverstone P H; Johnson B; Cowen P J
Does ondansetron attenuate amphetamine-induced behaviour in human volunteers?
Psychopharmacology 1992;107(1):140-1.
-
1992: da Roza Davis J M; Sharpley A L; Cowen P J
Slow wave sleep and 5-HT2 receptor sensitivity in generalised anxiety disorder: a pilot study with ritanserin.
Psychopharmacology 1992;108(3):387-9.
-
1992: Cowen P J
Serotonin receptor subtypes: neuroendocrine regulation in depression.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():96A.
-
1992: Silverstone P H; Oldman D; Johnson B; Cowen P J
Ondansetron, a 5-HT3 receptor antagonist, partially attenuates the effects of amphetamine: a pilot study in healthy volunteers.
International clinical psychopharmacology 1992;7(1):37-43.
-
1992: Best N R; Rees M P; Barlow D H; Cowen P J
Effect of estradiol implant on noradrenergic function and mood in menopausal subjects.
Psychoneuroendocrinology 1992;17(1):87-93.
-
1991: Cowen P J; McCance S L; Ware C J; Cohen P R; Chalmers J S; Julier D L
Lithium in tricyclic-resistant depression. Correlation of increased brain 5-HT function with clinical outcome.
The British journal of psychiatry : the journal of mental science 1991;159():341-6.
-
1991: Anderson I M; Cowen P J
Prolactin response to the dopamine antagonist, metoclopramide, in depression.
Biological psychiatry 1991;30(3):313-6.
-
1991: Geaney D P; Soper N; Shepstone B J; Goodwin G M; Cowen P J
Intravenous L-tryptophan and regional cerebral blood flow.
Biological psychiatry 1991;29(5):508-9.
-
1991: Smith C E; Ware C J; Cowen P J
Pindolol decreases prolactin and growth hormone responses to intravenous L-tryptophan.
Psychopharmacology 1991;103(1):140-2.
-
1991: Ellis P M; Gartside S E; Ware C J; Campling G M; Cowen P J
Does metergoline selectively attenuate 5-HT mediated prolactin release?
Psychopharmacology 1991;105(1):129-31.
-
1991: Walsh A E; Ware C J; Cowen P J
Lithium and 5-HT1A receptor sensitivity: a neuroendocrine study in healthy volunteers.
Psychopharmacology 1991;105(4):568-72.
-
1990: Sharpley A L; Solomon R A; Cowen P J
Sleep stability with home sleep recording and automatic sleep stage analysis.
Sleep 1990;13(6):538-40.
-
1990: Anderson I M; Parry-Billings M; Newsholme E A; Fairburn C G; Cowen P J
Dieting reduces plasma tryptophan and alters brain 5-HT function in women.
Psychological medicine 1990;20(4):785-91.
-
1990: Anderson I M; Parry-Billings M; Newsholme E A; Poortmans J R; Cowen P J
Decreased plasma tryptophan concentration in major depression: relationship to melancholia and weight loss.
Journal of affective disorders 1990;20(3):185-91.
-
1990: Cowen P J; Cohen P R; McCance S L; Friston K J
5-HT neuroendocrine responses during psychotropic drug treatment: an investigation of the effects of lithium.
Journal of neuroscience methods 1990;34(1-3):201-5.
-
1990: Sharpley A L; Gregory C A; Solomon R A; Cowen P J
Slow wave sleep and 5-HT2 receptor sensitivity during maintenance tricyclic antidepressant treatment.
Journal of affective disorders 1990;19(4):273-7.
-
1990: Cowen P J
Antidepressants: current concepts of mode of action.
International clinical psychopharmacology 1990;5 Suppl 3():45-55.
-
1990: Anderson I M; Gartside S E; Cowen P J
The effect of moderate weight loss on overnight melatonin secretion.
The British journal of psychiatry : the journal of mental science 1990;156():875-7.
-
1990: Geaney D P; Soper N; Shepstone B J; Cowen P J
Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease.
Lancet 1990;335(8704):1484-7.
-
1990: Gartside S E; Cowen P J
Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors.
European journal of pharmacology 1990;179(1-2):103-9.
-
1990: Cowen P J; McCance S L; Gelder M G; Grahame-Smith D G
Effect of amitriptyline on endocrine responses to intravenous L-tryptophan.
Psychiatry research 1990;31(2):201-8.
-
1990: Elphick M; Yang J D; Cowen P J
Effects of carbamazepine on dopamine- and serotonin-mediated neuroendocrine responses.
Archives of general psychiatry 1990;47(2):135-40.
-
1990: Gregory C A; Anderson I M; Cowen P J
Metergoline abolishes the prolactin response to buspirone.
Psychopharmacology 1990;100(2):283-4.
-
1990: Cowen P J; Anderson I M; Gartside S E
Endocrinological responses to 5-HT.
Annals of the New York Academy of Sciences 1990;600():250-7; discussion 257-9.
-
1990: Anderson I M; Cowen P J; Grahame-Smith D G
The effects of gepirone on neuroendocrine function and temperature in humans.
Psychopharmacology 1990;100(4):498-503.
-
1990: Sharpley A L; Solomon R A; Fernando A I; da Roza Davis J M; Cowen P J
Dose-related effects of selective 5-HT2 receptor antagonists on slow wave sleep in humans.
Psychopharmacology 1990;101(4):568-9.
-
1989: Grasby P M; Begg E J; Gartside S E; Cowen P J
Effect of idazoxan on evening melatonin plasma concentrations in healthy volunteers.
Biological psychiatry 1989;26(4):412-6.
-
1989: Anderson I M; Crook W S; Gartside S E; Parry-Billings M; Newsholme E A; Cowen P J
Effect of moderate weight loss on prolactin secretion in normal female volunteers.
Psychiatry research 1989;29(2):161-7.
-
1989: Anderson I M; Crook W S; Gartside S E; Fairburn C G; Cowen P J
The effect of moderate weight loss on overnight growth hormone and cortisol secretion in healthy female volunteers.
Journal of affective disorders 1989;16(2-3):197-202.
-
1989: Cowen P J; Parry-Billings M; Newsholme E A
Decreased plasma tryptophan levels in major depression.
Journal of affective disorders 1989;16(1):27-31.
-
1989: McCance S L; Cohen P R; Cowen P J
Lithium increases 5-HT-mediated prolactin release.
Psychopharmacology 1989;99(2):276-81.
-
1989: Cowen P J; McCance S L; Cohen P R; Julier D L
Lithium increases 5-HT-mediated neuroendocrine responses in tricyclic resistant depression.
Psychopharmacology 1989;99(2):230-2.
-
1989: Best N R; Barlow D H; Rees M P; Cowen P J
Lack of effect of oestradiol implant on platelet imipramine and 5-HT2 receptor binding in menopausal subjects.
Psychopharmacology 1989;98(4):561.
-
1989: Friston K J; Sharpley A L; Solomon R A; Cowen P J
Lithium increases slow wave sleep: possible mediation by brain 5-HT2 receptors?
Psychopharmacology 1989;98(1):139-40.
-
1988: Sharpley A L; Solomon R A; Cowen P J
Evaluation of first night effect using ambulatory monitoring and automatic sleep stage analysis.
Sleep 1988;11(3):273-6.
-
1987: Goodwin G M; Fairburn C G; Cowen P J
Dieting changes serotonergic function in women, not men: implications for the aetiology of anorexia nervosa?
Psychological medicine 1987;17(4):839-42.
-
1987: Grasby P M; Cowen P J
The pineal and psychiatry: still fumbling in the dark?
Psychological medicine 1987;17(4):817-20.
-
1987: Cowen P J; Charig E M; Fraser S; Elliott J M
Platelet 5-HT receptor binding during depressive illness and tricyclic antidepressant treatment.
Journal of affective disorders 1987;13(1):45-50.
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