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Alison Cox

Research Profile

Living Beings

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Darren A Yuen; Yanling Zhang; Lei Zhu; Suzanne L Advani; Kim A Connelly; Alison J Cox; Ian W Gibson; Raymond C Harris; M Golam Kabir; Darren J Kelly; Bailey E Stead; Takamune Takahashi; Tomoko Takano; Kerri Thai; Kathryn E White; Andrew Advani
eNOS deficiency predisposes podocytes to injury in diabetes.
Yuan Zhang; Alison J Cox; Amanda J Edgley; Richard E Gilbert; Andrew R Kompa; Henry Krum; Andrew K Powell; David I Stapleton; Bing Wang; Spencer J Williams; Steven C Zammit; Darren J Kelly
FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy.
Richard E Gilbert; Alison J Cox; Henry Krum; Robyn Langham; David I Stapleton; Spencer J Williams; Steven C Zammit; Yuan Zhang; Darren J Kelly
A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat.

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All Publications

2012: Darren A Yuen; Yanling Zhang; Lei Zhu; Suzanne L Advani; Kim A Connelly; Alison J Cox; Ian W Gibson; Raymond C Harris; M Golam Kabir; Darren J Kelly; Bailey E Stead; Takamune Takahashi; Tomoko Takano; Kerri Thai; Kathryn E White; Andrew Advani
eNOS deficiency predisposes podocytes to injury in diabetes.
Journal of the American Society of Nephrology : JASN 2012;23(11):1810-23.
2012: Yuan Zhang; Alison J Cox; Amanda J Edgley; Richard E Gilbert; Andrew R Kompa; Henry Krum; Andrew K Powell; David I Stapleton; Bing Wang; Spencer J Williams; Steven C Zammit; Darren J Kelly
FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy.
European journal of heart failure 2012;14(5):549-62.
2012: Richard E Gilbert; Alison J Cox; Henry Krum; Robyn Langham; David I Stapleton; Spencer J Williams; Steven C Zammit; Yuan Zhang; Darren J Kelly
A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat.
PloS one 2012;7(10):e47160.
2011: Hirobumi Tokuyama; Yuan Zhang; Alison J Cox; Renae M Gow; Darren J Kelly; Sandra Kim; Robyn G Langham; Richard E Gilbert
Protein kinase C β inhibition ameliorates experimental mesangial proliferative glomerulonephritis.
Nephrology (Carlton, Vic.) 2011;16(7):649-55.
2011: Andrew Advani; Alison J Cox; Richard E Gilbert; Kathryn J Wiggins; Yuan Zhang; Darren J Kelly
Inhibition of the epidermal growth factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy.
Nephrology (Carlton, Vic.) 2011;16(6):573-81.
2009: Steven C Zammit; Alison J Cox; Renae M Gow; Yuan Zhang; Richard E Gilbert; Henry Krum; Darren J Kelly; Spencer J Williams
Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates.
Bioorganic & medicinal chemistry letters 2009;19(24):7003-6.
2009: Darren J Kelly; Amanda J Edgley; Yuan Zhang; Keng-Ee Thai; Sih Min Tan; Alison J Cox; Andrew Advani; Kim Connelly; Catharine I Whiteside; Richard E Gilbert
Protein kinase C-beta inhibition attenuates the progression of nephropathy in non-diabetic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(6):1782-90.
2008: Robyn G Langham; Darren J Kelly; R M Gow; Y Zhang; Alison J Cox; W Qi; K Thai; C A Pollock; P K Christensen; H-H Parving; Richard E Gilbert
Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control.
Diabetologia 2008;51(4):668-74.
2007: Darren J Kelly; Yuan Zhang; Kim Connelly; Alison J Cox; Jennifer Martin; Henry Krum; Richard E Gilbert
Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2007;293(5):H2860-9.
2007: Kim Connelly; Darren J Kelly; Yuan Zhang; David L Prior; Jennifer Martin; Alison J Cox; K Thai; M P Feneley; james/jim Tsoporis; K E White; Henry Krum; Richard E Gilbert
Functional, structural and molecular aspects of diastolic heart failure in the diabetic (mRen-2)27 rat.
Cardiovascular research 2007;76(2):280-91.
2007: Andrew Advani; Darren J Kelly; Suzanne L Advani; Alison J Cox; Kerri Thai; Yuan Zhang; Kathryn E White; Renae M Gow; Sally M Marshall; Brent M Steer; Philip A Marsden; P Elizabeth Rakoczy; Richard E Gilbert
Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14448-53.
2006: Darren J Kelly; Yuan Zhang; Alison J Cox; Richard E Gilbert
Combination therapy with tranilast and angiotensin-converting enzyme inhibition provides additional renoprotection in the remnant kidney model.
Kidney international 2006;69(11):1954-60.
2005: Andrew Boyle; Darren J Kelly; Yuan Zhang; Alison J Cox; Renae M Gow; Kerrie Way; Silviu Itescu; Henry Krum; Richard E Gilbert
Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction.
Journal of molecular and cellular cardiology 2005;39(2):213-21.
2005: Jennifer Martin; Darren J Kelly; Sally A Mifsud; Yuan Zhang; Alison J Cox; Fiona See; Henry Krum; Jennifer L Wilkinson-Berka; Richard E Gilbert
Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta.
Cardiovascular research 2005;65(3):694-701.
2004: Darren J Kelly; Alison J Cox; Renae M Gow; Yuan Zhang; Bruce E Kemp; Richard E Gilbert
Platelet-derived growth factor receptor transactivation mediates the trophic effects of angiotensin II in vivo.
Hypertension 2004;44(2):195-202.
2004: John Kanellis; Vicki Levidiotis; Tiffany Khong; Alison J Cox; Steven A Stacker; Richard E Gilbert; Mark E Cooper; David A Power
A study of VEGF and its receptors in two rat models of proteinuria.
Nephron. Physiology 2004;96(1):P26-36.
2004: Robyn G Langham; Darren J Kelly; Alison J Cox; Renae M Gow; Harry Holthofer; Richard E Gilbert
Angiotensin II-induced proteinuria and expression of the podocyte slit pore membrane protein, nephrin.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(1):262-3.
2003: Geoffrey Boner; Alison J Cox; Darren J Kelly; Ana Tobar; Joëlle Bernheim; Robyn G Langham; Mark E Cooper; Richard E Gilbert
Does vascular endothelial growth factor (VEGF) play a role in the pathogenesis of minimal change disease?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(11):2293-9.
2003: F Bonnet; Z Cao; M E Cooper; Alison J Cox; Darren J Kelly; Richard E Gilbert
Tranilast attenuates vascular hypertrophy, matrix accumulation and growth factor overexpression in experimental diabetes.
Diabetes & metabolism 2003;29(4 Pt 1):386-92.
2003: Susan E Jones; Darren J Kelly; Alison J Cox; Yuan Zhang; Renae M Gow; Richard E Gilbert
Mast cell infiltration and chemokine expression in progressive renal disease.
Kidney international 2003;64(3):906-13.
2003: Darren J Kelly; Claire Hepper; Leonard L Wu; Alison J Cox; Richard E Gilbert
Vascular endothelial growth factor expression and glomerular endothelial cell loss in the remnant kidney model.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(7):1286-92.
2002: Robyn G Langham; Darren J Kelly; Alison J Cox; Napier M Thomson; Harry Holthöfer; Philippe Zaoui; Nicole Pinel; Daniel Cordonnier; Richard E Gilbert
Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition.
Diabetologia 2002;45(11):1572-6.
2002: Darren J Kelly; Petri Aaltonen; Alison J Cox; Jon R Rumble; Robyn G Langham; Sianna Panagiotopoulos; George Jerums; Harry Holthöfer; Richard E Gilbert
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(7):1327-32.
2002: Darren J Kelly; Jennifer L Wilkinson-Berka; Sharon D Ricardo; Alison J Cox; Richard E Gilbert
Progression of tubulointerstitial injury by osteopontin-induced macrophage recruitment in advanced diabetic nephropathy of transgenic (mRen-2)27 rats.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(6):985-91.
2002: John Kanellis; Kathy Paizis; Alison J Cox; Steven A Stacker; Richard E Gilbert; Mark E Cooper; David A Power
Renal ischemia-reperfusion increases endothelial VEGFR-2 without increasing VEGF or VEGFR-1 expression.
Kidney international 2002;61(5):1696-706.
2002: Darren J Kelly; Alison J Cox; Mary Tolcos; Mark E Cooper; Jennifer L Wilkinson-Berka; Richard E Gilbert
Attenuation of tubular apoptosis by blockade of the renin-angiotensin system in diabetic Ren-2 rats.
Kidney international 2002;61(1):31-9.
2001: Darren J Kelly; Richard E Gilbert; Alison J Cox; T Soulis; George Jerums; Mark E Cooper
Aminoguanidine ameliorates overexpression of prosclerotic growth factors and collagen deposition in experimental diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2001;12(10):2098-107.
2000: Richard E Gilbert; Darren J Kelly; Alison J Cox; Jennifer L Wilkinson-Berka; Jon R Rumble; Tanya M Osicka; Sianna Panagiotopoulos; V Lee; EC Hendrich; George Jerums; Mark E Cooper
Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hyperpermeability in experimental diabetes.
Diabetologia 2000;43(11):1360-7.
2000: Zemin Cao; Mark E Cooper; L L Wu; Alison J Cox; Karin A Jandeleit-Dahm; Darren J Kelly; Richard E Gilbert
Blockade of the renin-angiotensin and endothelin systems on progressive renal injury.
Hypertension 2000;36(4):561-8.
2000: Darren J Kelly; Sandford L Skinner; Richard E Gilbert; Alison J Cox; Mark E Cooper; Jennifer L Wilkinson-Berka
Effects of endothelin or angiotensin II receptor blockade on diabetes in the transgenic (mRen-2)27 rat.
Kidney international 2000;57(5):1882-94.
2000: Richard E Gilbert; Jon R Rumble; Zemin Cao; Alison J Cox; Pauline van Eeden; Terri J Allen; Darren J Kelly; Mark E Cooper
Endothelin receptor antagonism ameliorates mast cell infiltration, vascular hypertrophy, and epidermal growth factor expression in experimental diabetes.
Circulation research 2000;86(2):158-65.
2000: Karin A Jandeleit-Dahm; Jon R Rumble; Alison J Cox; Darren J Kelly; Marie A Dziadek; Mark E Cooper; Richard E Gilbert
SPARC gene expression is increased in diabetes-related mesenteric vascular hypertrophy.
Microvascular research 2000;59(1):61-71.
1999: Mark E Cooper; D Vranes; S Youssef; Steven A Stacker; Alison J Cox; Bishoy Rizkalla; David Casley; Leon A Bach; Darren J Kelly; Richard E Gilbert
Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes.
Diabetes 1999;48(11):2229-39.
1999: Karin A Jandeleit-Dahm; Z Cao; Alison J Cox; D J Kelly; Richard E Gilbert; Mark E Cooper
Role of hyperlipidemia in progressive renal disease: focus on diabetic nephropathy.
Kidney international. Supplement 1999;71():S31-6.
1999: Richard E Gilbert; Alison J Cox; Darren J Kelly; Jennifer L Wilkinson-Berka; E H Sage; George Jerums; Mark E Cooper
Localization of secreted protein acidic and rich in cysteine (SPARC) expression in the rat eye.
Connective tissue research 1999;40(4):295-303.
1992: Leon A Bach; Alison J Cox; Frederick Mendelsohn; A C Herington; George Werther; George Jerums
Focal induction of IGF binding proteins in proximal tubules of diabetic rat kidney.
Diabetes 1992;41(4):499-507.
1991: L A Bach; Alison J Cox; George Jerums
Diabetes-related renal growth and IGF-I accumulation in castrated rats.
Diabetes research and clinical practice 1991;14(1):15-20.
1991: H A Jonas; Alison J Cox
Insulin receptor sub-types in a human lymphoid-derived cell line (IM-9): differential regulation by insulin, dexamethasone and monensin.
Journal of receptor research 1991;11(5):813-29.
1990: M A Thompson; Alison J Cox; R H Whitehead; H A Jonas
Autocrine regulation of human tumor cell proliferation by insulin-like growth factor II: an in-vitro model.
Endocrinology 1990;126(6):3033-42.
1990: H A Jonas; Alison J Cox
Insulin-like growth factor binding to the atypical insulin receptors of a human lymphoid-derived cell line (IM-9).
The Biochemical journal 1990;266(3):737-42.
1990: Graeme P Young; T M Taranto; H A Jonas; Alison J Cox; A Hogg; George Werther
Insulin-like growth factors and the developing and mature rat small intestine: receptors and biological actions.
Digestion 1990;46 Suppl 2():240-52.
1989: H A Jonas; Alison J Cox; Leonard C Harrison
Delineation of atypical insulin receptors from classical insulin and type I insulin-like growth factor receptors in human placenta.
The Biochemical journal 1989;257(1):101-7.