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Gary Cox
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Research Profile (preview)
Living Beings
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Chemicals & Drugs
Physiology
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Network (preview)
36
Perfect, John
31
Heitman, Joseph
6
Giles, Steven
6
McDade, Henry
6
Casadevall, Arturo
5
Toffaletti, Dena
5
Wang, Ping
5
Alspaugh, Andrew
5
Bahn, Yong-Sun
4
Gottfredsson, Magnús
4
Fox, Deborah
4
McCusker, John
4
Heinrich, Garrett
3
Yang, Zhonghui
3
Nichols, Connie
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All Publications
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2009: Taylor Steve M; Lou Jun-Yang; Cox Gary M
Thanks for the memories.
The American journal of medicine 2009;122(9):827-9.
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2009: Byrnes Edmond J; Li Wenjun; Lewit Yonathan; Perfect John R; Carter Dee A; Cox Gary M; Heitman Joseph
First reported case of Cryptococcus gattii in the Southeastern USA: implications for travel-associated acquisition of an emerging pathogen.
PloS one 2009;4(6):e5851.
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2007: Wormley Floyd L; Perfect John R; Steele Chad; Cox Gary M
Protection against cryptococcosis by using a murine gamma interferon-producing Cryptococcus neoformans strain.
Infection and immunity 2007;75(3):1453-62.
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2006: Petzold Elizabeth Wills; Himmelreich Uwe; Mylonakis Eleftherios; Rude Thomas; Toffaletti Dena; Cox Gary M; Miller Jackie L; Perfect John R
Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans.
Infection and immunity 2006;74(10):5877-87.
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2006: Liu Min; Du Ping; Heinrich Garrett; Cox Gary M; Gelli Angie
Cch1 mediates calcium entry in Cryptococcus neoformans and is essential in low-calcium environments.
Eukaryotic cell 2006;5(10):1788-96.
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2006: Bahn Yong-Sun; Kojima Kaihei; Cox Gary M; Heitman Joseph
A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development, and virulence of Cryptococcus neoformans.
Molecular biology of the cell 2006;17(7):3122-35.
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2006: Fraser James A; Lim Shirlene M C; Diezmann Stephanie; Wenink Emily C; Arndt Cristl G; Cox Gary M; Dietrich Fred S; Heitman Joseph
Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale.
FEMS yeast research 2006;6(4):620-4.
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2006: Xue Chaoyang; Bahn Yong-Sun; Cox Gary M; Heitman Joseph
G protein-coupled receptor Gpr4 senses amino acids and activates the cAMP-PKA pathway in Cryptococcus neoformans.
Molecular biology of the cell 2006;17(2):667-79.
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2005: Bahn Yong-Sun; Cox Gary M; Perfect John R; Heitman Joseph
Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence.
Current biology : CB 2005;15(22):2013-20.
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2005: Nielsen Kirsten; Marra Robert E; Hagen Ferry; Boekhout Teun; Mitchell Thomas G; Cox Gary M; Heitman Joseph
Interaction between genetic background and the mating-type locus in Cryptococcus neoformans virulence potential.
Genetics 2005;171(3):975-83.
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2005: Wormley F L; Heinrich G; Miller J L; Perfect J R; Cox G M
Identification and characterization of an SKN7 homologue in Cryptococcus neoformans.
Infection and immunity 2005;73(8):5022-30.
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2005: Nielsen Kirsten; Cox Gary M; Litvintseva Anastasia P; Mylonakis Eleftherios; Malliaris Stephanie D; Benjamin Daniel K; Giles Steven S; Mitchell Thomas G; Casadevall Arturo; Perfect John R; Heitman Joseph
Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection.
Infection and immunity 2005;73(8):4922-33.
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2005: Bahn Yong-Sun; Kojima Kaihei; Cox Gary M; Heitman Joseph
Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformans.
Molecular biology of the cell 2005;16(5):2285-300.
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2005: Wormley Floyd L; Cox Gary M; Perfect John R
Evaluation of host immune responses to pulmonary cryptococcosis using a temperature-sensitive C. neoformans calcineurin A mutant strain.
Microbial pathogenesis 2005;38(2-3):113-23.
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2005: Pukkila-Worley Read; Gerrald Quincy D; Kraus Peter R; Boily Marie-Josée; Davis Matthew J; Giles Steven S; Cox Gary M; Heitman Joseph; Alspaugh J Andrew
Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade.
Eukaryotic cell 2005;4(1):190-201.
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2005: Giles Steven S; Batinic-Haberle Ines; Perfect John R; Cox Gary M
Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth.
Eukaryotic cell 2005;4(1):46-54.
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2005: Giles Steven S; Perfect John R; Cox Gary M
Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans.
Fungal genetics and biology : FG & B 2005;42(1):20-9.
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2004: Bahn Yong-Sun; Hicks Julie K; Giles Steven S; Cox Gary M; Heitman Joseph
Adenylyl cyclase-associated protein Aca1 regulates virulence and differentiation of Cryptococcus neoformans via the cyclic AMP-protein kinase A cascade.
Eukaryotic cell 2004;3(6):1476-91.
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2004: Kraus Peter R; Boily Marie-Josée; Giles Steven S; Stajich Jason E; Allen Andria; Cox Gary M; Dietrich Fred S; Perfect John R; Heitman Joseph
Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarray.
Eukaryotic cell 2004;3(5):1249-60.
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2004: Pascon Renata C; Ganous Tonya M; Kingsbury Joanne M; Cox Gary M; McCusker John H
Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence.
Microbiology (Reading, England) 2004;150(Pt 9):3013-23.
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2004: D'Souza Cletus A; Hagen Ferry; Boekhout Teun; Cox Gary M; Heitman Joseph
Investigation of the basis of virulence in serotype A strains of Cryptococcus neoformans from apparently immunocompetent individuals.
Current genetics 2004;46(2):92-102.
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2004: Kingsbury Joanne M; Yang Zhonghui; Ganous Tonya M; Cox Gary M; McCusker John H
Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans.
Eukaryotic cell 2004;3(3):752-63.
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2004: Hull Christina M; Cox Gary M; Heitman Joseph
The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans.
Infection and immunity 2004;72(6):3643-5.
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2004: Kingsbury Joanne M; Yang Zhonghui; Ganous Tonya M; Cox Gary M; McCusker John H
Cryptococcus neoformans Ilv2p confers resistance to sulfometuron methyl and is required for survival at 37 degrees C and in vivo.
Microbiology (Reading, England) 2004;150(Pt 5):1547-58.
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2004: Hicks Julie K; D'Souza Cletus A; Cox Gary M; Heitman Joseph
Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans.
Eukaryotic cell 2004;3(1):14-26.
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2003: de Jesús-Berríos Marisol; Liu Limin; Nussbaum Jesse C; Cox Gary M; Stamler Jonathan S; Heitman Joseph
Enzymes that counteract nitrosative stress promote fungal virulence.
Current biology : CB 2003;13(22):1963-8.
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2003: Fox Deborah S; Cox Gary M; Heitman Joseph
Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans.
Eukaryotic cell 2003;2(5):1025-35.
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2003: Luberto Chiara; Martinez-Mariño Beatriz; Taraskiewicz Daniel; Bolaños Benjamin; Chitano Pasquale; Toffaletti Dena L; Cox Gary M; Perfect John R; Hannun Yusuf A; Balish Edward; Del Poeta Maurizio
Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans.
The Journal of clinical investigation 2003;112(7):1080-94.
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2003: Akhter Shamima; McDade Henry C; Gorlach Jenifer M; Heinrich Garrett; Cox Gary M; Perfect John R
Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans.
Infection and immunity 2003;71(10):5794-802.
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2003: Nielsen Kirsten; Cox Gary M; Wang Ping; Toffaletti Dena L; Perfect John R; Heitman Joseph
Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates.
Infection and immunity 2003;71(9):4831-41.
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2003: Davidson Robert C; Nichols Connie B; Cox Gary M; Perfect John R; Heitman Joseph
A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans.
Molecular microbiology 2003;49(2):469-85.
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2003: Kraus Peter R; Fox Deborah S; Cox Gary M; Heitman Joseph
The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function.
Molecular microbiology 2003;48(5):1377-87.
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2003: Cox Gary M; Harrison Thomas S; McDade Henry C; Taborda Carlos P; Heinrich Garrett; Casadevall Arturo; Perfect John R
Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages.
Infection and immunity 2003;71(1):173-80.
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2002: Rude Thomas H; Toffaletti Dena L; Cox Gary M; Perfect John R
Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans.
Infection and immunity 2002;70(10):5684-94.
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2002: Yang Zhonghui; Pascon Renata C; Alspaugh Andrew; Cox Gary M; McCusker John H
Molecular and genetic analysis of the Cryptococcus neoformans MET3 gene and a met3 mutant.
Microbiology (Reading, England) 2002;148(Pt 8):2617-25.
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2002: Shen Wei-Chiang; Davidson Robert C; Cox Gary M; Heitman Joseph
Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans.
Eukaryotic cell 2002;1(3):366-77.
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2002: Wang Ping; Nichols Connie B; Lengeler Klaus B; Cardenas Maria E; Cox Gary M; Perfect John R; Heitman Joseph
Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans.
Eukaryotic cell 2002;1(2):257-72.
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2002: Wright Lesley C; Chen Sharon C A; Wilson Christabel F; Simpanya Mukoma F; Blackstock Rebecca; Cox Gary M; Murphy Juneann W; Sorrell Tania C
Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans.
FEMS microbiology letters 2002;209(2):175-81.
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2002: Alspaugh J Andrew; Pukkila-Worley Read; Harashima Toshiaki; Cavallo Lora M; Funnell Deanna; Cox Gary M; Perfect John R; Kronstad James W; Heitman Joseph
Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans.
Eukaryotic cell 2002;1(1):75-84.
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2002: Gorlach Jenifer M; McDade Henry C; Perfect John R; Cox Gary M
Antisense repression in Cryptococcus neoformans as a laboratory tool and potential antifungal strategy.
Microbiology (Reading, England) 2002;148(Pt 1):213-9.
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2002: Waugh Michael S; Nichols Connie B; DeCesare Cameron M; Cox Gary M; Heitman Joseph; Alspaugh J Andrew
Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans.
Microbiology (Reading, England) 2002;148(Pt 1):191-201.
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2001: Gottfredsson M; Jessup C J; Cox G M; Perfect J R; Ghannoum M A
Fungal phospholipase activity and susceptibility to lipid preparations of amphotericin B.
Antimicrobial agents and chemotherapy 2001;45(11):3231-3.
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2001: Wang P; Cardenas M E; Cox G M; Perfect J R; Heitman J
Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans.
EMBO reports 2001;2(6):511-8.
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2001: Wills E A; Roberts I S; Del Poeta M; Rivera J; Casadevall A; Cox G M; Perfect J R
Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity.
Molecular microbiology 2001;40(3):610-20.
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2001: D'Souza C A; Alspaugh J A; Yue C; Harashima T; Cox G M; Perfect J R; Heitman J
Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans.
Molecular and cellular biology 2001;21(9):3179-91.
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2001: McDade H C; Cox G M
A new dominant selectable marker for use in Cryptococcus neoformans.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2001;39(1):151-4.
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2001: Fox D S; Cruz M C; Sia R A; Ke H; Cox G M; Cardenas M E; Heitman J
Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans.
Molecular microbiology 2001;39(4):835-49.
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2001: Cox G M; McDade H C; Chen S C; Tucker S C; Gottfredsson M; Wright L C; Sorrell T C; Leidich S D; Casadevall A; Ghannoum M A; Perfect J R
Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans.
Molecular microbiology 2001;39(1):166-75.
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2001: Lengeler K B; Cox G M; Heitman J
Serotype AD strains of Cryptococcus neoformans are diploid or aneuploid and are heterozygous at the mating-type locus.
Infection and immunity 2001;69(1):115-22.
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2000: Lengeler K B; Wang P; Cox G M; Perfect J R; Heitman J
Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14455-60.
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2000: Görlach J; Fox D S; Cutler N S; Cox G M; Perfect J R; Heitman J
Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.
The EMBO journal 2000;19(14):3618-29.
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2000: Rosas A L; Nosanchuk J D; Feldmesser M; Cox G M; McDade H C; Casadevall A
Synthesis of polymerized melanin by Cryptococcus neoformans in infected rodents.
Infection and immunity 2000;68(5):2845-53.
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2000: Cruz M C; Sia R A; Olson M; Cox G M; Heitman J
Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.
Infection and immunity 2000;68(2):982-5.
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2000: Cox G M; Mukherjee J; Cole G T; Casadevall A; Perfect J R
Urease as a virulence factor in experimental cryptococcosis.
Infection and immunity 2000;68(2):443-8.
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1999: Yue C; Cavallo L M; Alspaugh J A; Wang P; Cox G M; Perfect J R; Heitman J
The STE12alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans.
Genetics 1999;153(4):1601-15.
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1999: Gottfredsson M; Cox G M; Indridason O S; de Almeida G M; Heald A E; Perfect J R
Association of plasma levels of human immunodeficiency virus type 1 RNA and oropharyngeal Candida colonization.
The Journal of infectious diseases 1999;180(2):534-7.
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1998: Gottfredsson M; Cox G M; Perfect J R
Molecular methods for epidemiological and diagnostic studies of fungal infections.
Pathology 1998;30(4):405-18.
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1996: Cox G M; Toffaletti D L; Perfect J R
Dominant selection system for use in Cryptococcus neoformans.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology 1996;34(6):385-91.
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1996: Perfect J R; Cox G M; Dodge R K; Schell W A
In vitro and in vivo efficacies of the azole SCH56592 against Cryptococcus neoformans.
Antimicrobial agents and chemotherapy 1996;40(8):1910-3.
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1996: Heald A E; Cox G M; Schell W A; Bartlett J A; Perfect J R
Oropharyngeal yeast flora and fluconazole resistance in HIV-infected patients receiving long-term continuous versus intermittent fluconazole therapy.
AIDS (London, England) 1996;10(3):263-8.
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1995: Cox G M; Sexton D J
Photo quiz. Rocky Mountain Spotted Fever.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;21(2):315, 429.
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1995: Cox G M; Rude T H; Dykstra C C; Perfect J R
The actin gene from Cryptococcus neoformans: structure and phylogenetic analysis.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology 1995;33(4):261-6.
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1994: Cox G M; Schell W A; Scher R L; Perfect J R
First report of involvement of Nodulisporium species in human disease.
Journal of clinical microbiology 1994;32(9):2301-4.
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1993: Perfect J R; Ketabchi N; Cox G M; Ingram C W; Beiser C L
Karyotyping of Cryptococcus neoformans as an epidemiological tool.
Journal of clinical microbiology 1993;31(12):3305-9.
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