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Anna Cozzi

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Hela Cells

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Electrophoresis, Polyacrylamide Gel

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Escherichia coli

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Alessandro Campanella; Anna Cozzi; Barbara Garavaglia; Michela Guaraldo; Daniela Privitera; Elisabetta Rovelli; Paolo Santambrogio; Chiara Barzaghi; Sonia Levi
Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.
Paolo Santambrogio; Alessandro Campanella; Vincenza Causarano; Anna Cozzi; Laura Cremonesi; Matteo Giovanni Della Porta; Benedetta Gaia Erba; Anna Gallì; Rosangela Invernizzi; Sonia Levi
Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation.
Anna Cozzi; Elisabetta Rovelli; Grazia Frizzale; Alessandro Campanella; Mario Amendola; Paolo Arosio; Sonia Levi
Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy.

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All Publications

2012: Alessandro Campanella; Anna Cozzi; Barbara Garavaglia; Michela Guaraldo; Daniela Privitera; Elisabetta Rovelli; Paolo Santambrogio; Chiara Barzaghi; Sonia Levi
Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.
Human molecular genetics 2012;21(18):4049-59.
2011: Paolo Santambrogio; Alessandro Campanella; Vincenza Causarano; Anna Cozzi; Laura Cremonesi; Matteo Giovanni Della Porta; Benedetta Gaia Erba; Anna Gallì; Rosangela Invernizzi; Sonia Levi
Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation.
Haematologica 2011;96(10):1424-32.
2010: Anna Cozzi; Elisabetta Rovelli; Grazia Frizzale; Alessandro Campanella; Mario Amendola; Paolo Arosio; Sonia Levi
Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy.
Neurobiology of disease 2010;37(1):77-85.
2006: Anna Cozzi; Paolo Santambrogio; Barbara Corsi; Alessandro Campanella; Paolo Arosio; Sonia Levi
Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder.
Neurobiology of disease 2006;23(3):644-52.
2005: Sonia Levi; Anna Cozzi; Paolo Arosio
Neuroferritinopathy: a neurodegenerative disorder associated with L-ferritin mutation.
Best practice & research. Clinical haematology 2005;18(2):265-76.
2004: Alessandro Campanella; Grazia Isaya; Heather A O'Neill; Paolo Santambrogio; Anna Cozzi; Paolo Arosio; Sonia Levi
The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast.
Human molecular genetics 2004;13(19):2279-88.
2004: Anna Cozzi; Barbara Corsi; Sonia Levi; Paolo Santambrogio; Giorgio Biasiotto; Paolo Arosio
Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin.
Blood 2004;103(6):2377-83.
2003: Anna Cozzi; Sonia Levi; Barbara Corsi; Paolo Santambrogio; Alessandro Campanella; Gianmario Gerardi; Paolo Arosio
Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells.
FEBS letters 2003;537(1-3):187-92.
2002: Barbara Corsi; Anna Cozzi; Paolo Arosio; Jim Drysdale; Paolo Santambrogio; Alessandro Campanella; Giorgio Biasiotto; Alberto Albertini; Sonia Levi
Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism.
The Journal of biological chemistry 2002;277(25):22430-7.
2000: Anna Cozzi; Barbara Corsi; Sonia Levi; Paolo Santambrogio; Alberto Albertini; Paolo Arosio
Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.
The Journal of biological chemistry 2000;275(33):25122-9.
2000: Paolo Santambrogio; Anna Cozzi; Sonia Levi; E Rovida; Fulvio Magni; Alberto Albertini; Paolo Arosio
Functional and immunological analysis of recombinant mouse H- and L-ferritins from Escherichia coli.
Protein expression and purification 2000;19(1):212-8.
1999: Barbara Corsi; Sonia Levi; Anna Cozzi; A Corti; D Altimare; Alberto Albertini; Paolo Arosio
Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces and iron-deficient phenotype.
FEBS letters 1999;460(1):149-52.
1998: Barbara Corsi; F Perrone; M Bourgeois; C Beaumont; M C Panzeri; Anna Cozzi; R Sangregorio; Paolo Santambrogio; Alberto Albertini; Paolo Arosio; Sonia Levi
Transient overexpression of human H- and L-ferritin chains in COS cells.
The Biochemical journal 1998;330 ( Pt 1)():315-20.
1997: Paolo Santambrogio; P Pinto; Sonia Levi; Anna Cozzi; E Rovida; Alberto Albertini; Peter J Artymiuk; P M Harrison; Paolo Arosio
Effects of modifications near the 2-, 3- and 4-fold symmetry axes on human ferritin renaturation.
The Biochemical journal 1997;322 ( Pt 2)():461-8.
1996: Sonia Levi; Paolo Santambrogio; Barbara Corsi; Anna Cozzi; Paolo Arosio
Evidence that residues exposed on the three-fold channels have active roles in the mechanism of ferritin iron incorporation.
The Biochemical journal 1996;317 ( Pt 2)():467-73.
1996: Paolo Santambrogio; Sonia Levi; Anna Cozzi; Barbara Corsi; Paolo Arosio
Evidence that the specificity of iron incorporation into homopolymers of human ferritin L- and H-chains is conferred by the nucleation and ferroxidase centres.
The Biochemical journal 1996;314 ( Pt 1)():139-44.
1994: Sonia Levi; Barbara Corsi; E Rovida; Anna Cozzi; Paolo Santambrogio; Alberto Albertini; Paolo Arosio
Construction of a ferroxidase center in human ferritin L-chain.
The Journal of biological chemistry 1994;269(48):30334-9.
1994: Sonia Levi; Paolo Santambrogio; Anna Cozzi; E Rovida; Barbara Corsi; E Tamborini; S Spada; Alberto Albertini; Paolo Arosio
The role of the L-chain in ferritin iron incorporation. Studies of homo and heteropolymers.
Journal of molecular biology 1994;238(5):649-54.
1994: Paolo Arosio; S Levi; Paolo Santambrogio; Anna Cozzi; E Rovida; Barbara Corsi; E Tamborini; S Spada; A Albertini
Chemico-physical and functional differences between H and L chains of human ferritin.
Advances in experimental medicine and biology 1994;356():13-21.
1993: Paolo Santambrogio; Sonia Levi; Anna Cozzi; E Rovida; Alberto Albertini; Paolo Arosio
Production and characterization of recombinant heteropolymers of human ferritin H and L chains.
The Journal of biological chemistry 1993;268(17):12744-8.
1992: Sonia Levi; S J Yewdall; Pauline M Harrison; Paolo Santambrogio; Anna Cozzi; E Rovida; Alberto Albertini; Paolo Arosio
Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin.
The Biochemical journal 1992;288 ( Pt 2)():591-6.
1991: Paolo Arosio; Sonia Levi; Paolo Santambrogio; Anna Cozzi; Alessandra Luzzago; Gianni Cesareni; Alberto Albertini
Structural and functional studies of human ferritin H and L chains.
Current studies in hematology and blood transfusion 1991;(58):127-31.
1990: Anna Cozzi; Paolo Santambrogio; Sonia Levi; Paolo Arosio
Iron detoxifying activity of ferritin. Effects of H and L human apoferritins on lipid peroxidation in vitro.
FEBS letters 1990;277(1-2):119-22.
1990: Paolo Arosio; Anna Cozzi; R Ingrassia; Sonia Levi; Alessandra Luzzago; G Ruggeri; C Iacobello; Paolo Santambrogio; Alberto Albertini
A mutational analysis of the epitopes of recombinant human H-ferritin.
Biochimica et biophysica acta 1990;1039(2):197-203.
1989: Anna Cozzi; Sonia Levi; Elena Bazzigaluppi; G Ruggeri; Paolo Arosio
Development of an immunoassay for all human isoferritins, and its application to serum ferritin evaluation.
Clinica chimica acta; international journal of clinical chemistry 1989;184(3):197-206.
1989: Sonia Levi; J Salfeld; F Franceschinelli; Anna Cozzi; M H Dorner; Paolo Arosio
Expression and structural and functional properties of human ferritin L-chain from Escherichia coli.
Biochemistry 1989;28(12):5179-84.
1988: Sonia Levi; Alessandra Luzzago; Gianni Cesareni; Anna Cozzi; F Franceschinelli; Alberto Albertini; Paolo Arosio
Mechanism of ferritin iron uptake: activity of the H-chain and deletion mapping of the ferro-oxidase site. A study of iron uptake and ferro-oxidase activity of human liver, recombinant H-chain ferritins, and of two H-chain deletion mutants.
The Journal of biological chemistry 1988;263(34):18086-92.
1987: Paolo Santambrogio; Anna Cozzi; Sonia Levi; Paolo Arosio
Human serum ferritin G-peptide is recognized by anti-L ferritin subunit antibodies and concanavalin-A.
British journal of haematology 1987;65(2):235-7.