David Craik

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Wang Conan K; Colgrave Michelle L; Ireland David C; Kaas Quentin; Craik David J
Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.
Daly Norelle L; Rosengren K Johan; Craik David J
Discovery, structure and biological activities of cyclotides.
Chan Lai Y; Wang Conan K L; Major Jodie M; Greenwood Kathryn P; Lewis Richard J; Craik David J; Daly Norelle L
Isolation and characterization of peptides from Momordica cochinchinensis seeds.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of David Craik (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Wang Conan K; Colgrave Michelle L; Ireland David C; Kaas Quentin; Craik David J
Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.
Biophysical journal 2009;97(5):1471-81.
2009: Daly Norelle L; Rosengren K Johan; Craik David J
Discovery, structure and biological activities of cyclotides.
Advanced drug delivery reviews 2009;61(11):918-30.
2009: Chan Lai Y; Wang Conan K L; Major Jodie M; Greenwood Kathryn P; Lewis Richard J; Craik David J; Daly Norelle L
Isolation and characterization of peptides from Momordica cochinchinensis seeds.
Journal of natural products 2009;72(8):1453-8.
2009: Trabi Manuela; Mylne Joshua S; Sando Lillian; Craik David J
Circular proteins from Melicytus (Violaceae) refine the conserved protein and gene architecture of cyclotides.
Organic & biomolecular chemistry 2009;7(11):2378-88.
2009: Craik David J
Circling the enemy: cyclic proteins in plant defence.
Trends in plant science 2009;14(6):328-35.
2009: Haugaard-Jönsson Linda M; Hossain Mohammed Akhter; Daly Norelle L; Craik David J; Wade John D; Rosengren K Johan
Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework.
The Biochemical journal 2009;419(3):619-27.
2009: Halai Reena; Craik David J
Conotoxins: natural product drug leads.
Natural product reports 2009;26(4):526-36.
2009: Haugaard-Jönsson Linda M; Hossain Mohammed Akhter; Daly Norelle L; Bathgate Ross A D; Wade John D; Craik David J; Rosengren K Johan
Structural properties of relaxin chimeras.
Annals of the New York Academy of Sciences 2009;1160():27-30.
2009: Rosengren K Johan; Bathgate Ross A D; Craik David J; Daly Norelle L; Haugaard-Jönsson Linda M; Hossain Mohammed Akhter; Wade John D
Structural insights into the function of relaxins.
Annals of the New York Academy of Sciences 2009;1160():20-6.
2009: Wang Conan K; Hu Shu-Hong; Martin Jennifer L; Sjögren Tove; Hajdu Janos; Bohlin Lars; Claeson Per; Göransson Ulf; Rosengren K Johan; Tang Jun; Tan Ning-Hua; Craik David J
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold.
The Journal of biological chemistry 2009;284(16):10672-83.
2009: Daly Norelle L; Craik David J
Structural studies of conotoxins.
IUBMB life 2009;61(2):144-50.
2009: Millard Emma L; Nevin Simon T; Loughnan Marion L; Nicke Annette; Clark Richard J; Alewood Paul F; Lewis Richard J; Adams David J; Craik David J; Daly Norelle L
Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues.
The Journal of biological chemistry 2009;284(8):4944-51.
2009: Colgrave Michelle L; Kotze Andrew C; Kopp Steven; McCarthy James S; Coleman Glen T; Craik David J
Anthelmintic activity of cyclotides: In vitro studies with canine and human hookworms.
Acta tropica 2009;109(2):163-6.
2009: Daly Norelle L; Chen Yi K; Rosengren K Johan; Marx Ute C; Phillips Martin L; Waring Alan J; Wang Wei; Lehrer Robert I; Craik David J
Retrocyclin-2: a potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif.
Advances in experimental medicine and biology 2009;611():577-8.
2009: Ireland David C; Colgrave Michelle L; Daly Norelle L; Craik David J
The discovery and development of a natural combinatorial peptide template: the cyclotides.
Advances in experimental medicine and biology 2009;611():477-8.
2009: Gruber Christian W; Cemazar Maia; Anderson Marilyn A; Craik David J
Enzyme mechanism and function of a novel plant PDI involved in the oxidative folding of cystine knot defense peptides.
Advances in experimental medicine and biology 2009;611():31-2.
2009: Marcellin Esteban; Gruber Christian W; Archer Colin; Craik David J; Nielsen Lars K
Proteome analysis of the hyaluronic acid-producing bacterium, Streptococcus zooepidemicus.
Proteome science 2009;7():13.
2009: Gruber Christian W; Cemazar Masa; Mechler Adam; Martin Lisandra L; Craik David J
Biochemical and biophysical characterization of a novel plant protein disulfide isomerase.
Biopolymers 2009;92(1):35-43.
2008: Callaghan Brid; Haythornthwaite Alison; Berecki Géza; Clark Richard J; Craik David J; Adams David J
Analgesic alpha-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(43):10943-51.
2008: Gruber Christian W; Elliott Alysha G; Ireland David C; Delprete Piero G; Dessein Steven; Göransson Ulf; Trabi Manuela; Wang Conan K; Kinghorn Andrew B; Robbrecht Elmar; Craik David J
Distribution and evolution of circular miniproteins in flowering plants.
The Plant cell 2008;20(9):2471-83.
2008: Jin Ai-Hua; Daly Norelle L; Nevin Simon T; Wang Ching-I A; Dutertre Sebastien; Lewis Richard J; Adams David J; Craik David J; Alewood Paul F
Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function.
Journal of medicinal chemistry 2008;51(18):5575-84.
2008: Saska Ivana; Colgrave Michelle L; Jones Alun; Anderson Marilyn A; Craik David J
Quantitative analysis of backbone-cyclised peptides in plants.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;872(1-2):107-14.
2008: Colgrave Michelle L; Kotze Andrew C; Ireland David C; Wang Conan K; Craik David J
The anthelmintic activity of the cyclotides: natural variants with enhanced activity.
Chembiochem : a European journal of chemical biology 2008;9(12):1939-45.
2008: Saska Ivana; Craik David J
Protease-catalysed protein splicing: a new post-translational modification?
Trends in biochemical sciences 2008;33(8):363-8.
2008: Haugaard-Jönsson Linda M; Hossain Mohammed Akhter; Daly Norelle L; Bathgate Ross A D; Wade John D; Craik David J; Rosengren K Johan
Structure of the R3/I5 chimeric relaxin peptide, a selective GPCR135 and GPCR142 agonist.
The Journal of biological chemistry 2008;283(35):23811-8.
2008: Imperial Julita S; Chen Ping; Sporning Annett; Terlau Heinrich; Daly Norelle L; Craik David J; Alewood Paul F; Olivera Baldomero M
Tyrosine-rich conopeptides affect voltage-gated K+ channels.
The Journal of biological chemistry 2008;283(34):23026-32.
2008: Plan Manuel Rey R; Saska Ivana; Cagauan Arsenia G; Craik David J
Backbone cyclised peptides from plants show molluscicidal activity against the rice pest Pomacea canaliculata (golden apple snail).
Journal of agricultural and food chemistry 2008;56(13):5237-41.
2008: Cemazar Masa; Joshi Ajinkya; Daly Norelle L; Mark Alan E; Craik David J
The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein.
Structure (London, England : 1993) 2008;16(6):842-51.
2008: Cemazar Masa; Craik David J
Microwave-assisted Boc-solid phase peptide synthesis of cyclic cysteine-rich peptides.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(6):683-9.
2008: Colgrave Michelle L; Kotze Andrew C; Huang Yen-Hua; O'Grady John; Simonsen Shane M; Craik David J
Cyclotides: natural, circular plant peptides that possess significant activity against gastrointestinal nematode parasites of sheep.
Biochemistry 2008;47(20):5581-9.
2008: Simonsen Shane M; Sando Lillian; Rosengren K Johan; Wang Conan K; Colgrave Michelle L; Daly Norelle L; Craik David J
Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.
The Journal of biological chemistry 2008;283(15):9805-13.
2008: Clark Richard J; Daly Norelle L; Halai Reena; Nevin Simon T; Adams David J; Craik David J
The three-dimensional structure of the analgesic alpha-conotoxin, RgIA.
FEBS letters 2008;582(5):597-602.
2008: Dutertre Sébastien; Croker Daniel; Daly Norelle L; Andersson Asa; Muttenthaler Markus; Lumsden Natalie G; Craik David J; Alewood Paul F; Guillon Gilles; Lewis Richard J
Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides.
The Journal of biological chemistry 2008;283(11):7100-8.
2008: Herrmann Anders; Burman Robert; Mylne Joshua S; Karlsson Gustav; Gullbo Joachim; Craik David J; Clark Richard J; Göransson Ulf
The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity.
Phytochemistry 2008;69(4):939-52.
2008: Gillon Amanda D; Saska Ivana; Jennings Cameron V; Guarino Rosemary F; Craik David J; Anderson Marilyn A
Biosynthesis of circular proteins in plants.
The Plant journal : for cell and molecular biology 2008;53(3):505-15.
2008: Kaas Quentin; Westermann Jan-C; Halai Reena; Wang Conan K L; Craik David J
ConoServer, a database for conopeptide sequences and structures.
Bioinformatics (Oxford, England) 2008;24(3):445-6.
2008: Barbeta Barbara L; Marshall Alan T; Gillon Amanda D; Craik David J; Anderson Marilyn A
Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1221-5.
2008: Wang Conan K L; Colgrave Michelle L; Gustafson Kirk R; Ireland David C; Goransson Ulf; Craik David J
Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis.
Journal of natural products 2008;71(1):47-52.
2008: Leta Aboye Teshome; Clark Richard J; Craik David J; Göransson Ulf
Ultra-stable peptide scaffolds for protein engineering-synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2.
Chembiochem : a European journal of chemical biology 2008;9(1):103-13.
2008: Wang Conan K L; Kaas Quentin; Chiche Laurent; Craik David J
CyBase: a database of cyclic protein sequences and structures, with applications in protein discovery and engineering.
Nucleic acids research 2008;36(Database issue):D206-10.
2008: Cemazar Masa; Gruber Christian W; Craik David J
Oxidative folding of cyclic cystine knot proteins.
Antioxidants & redox signaling 2008;10(1):103-11.
2008: Wang Conan K; Schirra Horst Joachim; Craik David J
NMRDyn: a program for NMR relaxation studies of protein association.
PloS one 2008;3(11):e3820.
2008: Westermann Jan-Christoph; Clark Richard J; Craik David J
Binding mode of alpha-conotoxins to an acetylcholine binding protein determined by saturation transfer difference NMR.
Protein and peptide letters 2008;15(9):910-4.
2008: Schirra Horst Joachim; Anderson Marilyn A; Craik David J
Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata.
Protein and peptide letters 2008;15(9):903-9.
2008: Westermann Jan-Christoph; Craik David J
NMR in peptide drug development.
Methods in molecular biology (Clifton, N.J.) 2008;494():87-113.
2008: Schirra Horst Joachim; Anderson Cameron G; Wilson William J; Kerr Linda; Craik David J; Waters Michael J; Lichanska Agnieszka M
Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study.
PloS one 2008;3(7):e2764.
2008: Mylne Joshua S; Craik David J
15N cyclotides by whole plant labeling.
Biopolymers 2008;90(4):575-80.
2008: Ireland David C; Wang Conan K L; Wilson Jennifer A; Gustafson Kirk R; Craik David J
Cyclotides as natural anti-HIV agents.
Biopolymers 2008;90(1):51-60.
2008: Ekberg J; Craik D J; Adams D J
Conotoxin modulation of voltage-gated sodium channels.
The international journal of biochemistry & cell biology 2008;40(11):2363-8.
2007: Nevin S T; Clark R J; Klimis H; Christie M J; Craik D J; Adams D J
Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?
Molecular pharmacology 2007;72(6):1406-10.
2007: Saska Ivana; Gillon Amanda D; Hatsugai Noriyuki; Dietzgen Ralf G; Hara-Nishimura Ikuko; Anderson Marilyn A; Craik David J
An asparaginyl endopeptidase mediates in vivo protein backbone cyclization.
The Journal of biological chemistry 2007;282(40):29721-8.
2007: Craik David
American Peptide Society - 20th Symposium: peptide vaccine and drug development.
IDrugs : the investigational drugs journal 2007;10(9):621-5.
2007: Daly Norelle L; Chen Yi-Kuang; Rosengren K Johan; Marx Ute C; Phillips Martin L; Waring Alan J; Wang Wei; Lehrer Robert I; Craik David J
Retrocyclin-2: structural analysis of a potent anti-HIV theta-defensin.
Biochemistry 2007;46(35):9920-8.
2007: Craik David J; Adams David J
Chemical modification of conotoxins to improve stability and activity.
ACS chemical biology 2007;2(7):457-68.
2007: Gruber Christian W; Cemazar Masa; Clark Richard J; Horibe Tomohisa; Renda Rosemary F; Anderson Marilyn A; Craik David J
A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins.
The Journal of biological chemistry 2007;282(28):20435-46.
2007: Plan Manuel Rey R; Göransson Ulf; Clark Richard J; Daly Norelle L; Colgrave Michelle L; Craik David J
The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides.
Chembiochem : a European journal of chemical biology 2007;8(9):1001-11.
2007: Craik David J; Clark Richard J; Daly Norelle L
Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins.
Expert opinion on investigational drugs 2007;16(5):595-604.
2007: Craik David J; Daly Norelle L
NMR as a tool for elucidating the structures of circular and knotted proteins.
Molecular bioSystems 2007;3(4):257-65.
2007: Craik David J; Cemazar Masa; Daly Norelle L
The chemistry and biology of cyclotides.
Current opinion in drug discovery & development 2007;10(2):176-84.
2007: Gruber Christian W; Cemazar Masa; Anderson Marilyn A; Craik David J
Insecticidal plant cyclotides and related cystine knot toxins.
Toxicon : official journal of the International Society on Toxinology 2007;49(4):561-75.
2007: Greenwood Kathryn P; Daly Norelle L; Brown Darren L; Stow Jennifer L; Craik David J
The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.
The international journal of biochemistry & cell biology 2007;39(12):2252-64.
2007: Jin Ai-Hua; Brandstaetter Hemma; Nevin Simon T; Tan Chia Chia; Clark Richard J; Adams David J; Alewood Paul F; Craik David J; Daly Norelle L
Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics.
BMC structural biology 2007;7():28.
2006: Lovelace Erica S; Armishaw Christopher J; Colgrave Michelle L; Wahlstrom Maria E; Alewood Paul F; Daly Norelle L; Craik David J
Cyclic MrIA: a stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter.
Journal of medicinal chemistry 2006;49(22):6561-8.
2006: Ireland David C; Colgrave Michelle L; Craik David J
A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.
The Biochemical journal 2006;400(1):1-12.
2006: Craik David
Animal, plant and microbial toxins - 15th World Congress.
IDrugs : the investigational drugs journal 2006;9(10):679-81.
2006: Gunasekera Sunithi; Daly Norelle L; Anderson Marilyn A; Craik David J
Chemical synthesis and biosynthesis of the cyclotide family of circular proteins.
IUBMB life 2006;58(9):515-24.
2006: Mulvenna Jason P; Mylne Joshua S; Bharathi Rekha; Burton Rachel A; Shirley Neil J; Fincher Geoffrey B; Anderson Marilyn A; Craik David J
Discovery of cyclotide-like protein sequences in graminaceous crop plants: ancestral precursors of circular proteins?
The Plant cell 2006;18(9):2134-44.
2006: Rosengren K Johan; Zhang Suode; Lin Feng; Daly Norelle L; Scott Daniel J; Hughes Richard A; Bathgate Ross A D; Craik David J; Wade John D
Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.
The Journal of biological chemistry 2006;281(38):28287-95.
2006: Rosengren K Johan; Daly Norelle L; Fornander Liselotte M; Jönsson Linda M H; Shirafuji Yoshinori; Qu Xiaoqing; Vogel Hans J; Ouellette Andre J; Craik David J
Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.
The Journal of biological chemistry 2006;281(38):28068-78.
2006: Gruber Christian W; Cemazar Masa; Heras Begoña; Martin Jennifer L; Craik David J
Protein disulfide isomerase: the structure of oxidative folding.
Trends in biochemical sciences 2006;31(8):455-64.
2006: Daly Norelle L; Chen Yi-Kuang; Foley Fiona M; Bansal Paramjit S; Bharathi Rekha; Clark Richard J; Sommerhoff Christian P; Craik David J
The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold.
The Journal of biological chemistry 2006;281(33):23668-75.
2006: Clark Richard J; Fischer Harald; Nevin Simon T; Adams David J; Craik David J
The synthesis, structural characterization, and receptor specificity of the alpha-conotoxin Vc1.1.
The Journal of biological chemistry 2006;281(32):23254-63.
2006: Marx Ute C; Daly Norelle L; Craik David J
NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids.
Magnetic resonance in chemistry : MRC 2006;44 Spec No():S41-50.
2006: Imperial Julita S; Bansal Paramjit S; Alewood Paul F; Daly Norelle L; Craik David J; Sporning Annett; Terlau Heinrich; López-Vera Estuardo; Bandyopadhyay Pradip K; Olivera Baldomero M
A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.
Biochemistry 2006;45(27):8331-40.
2006: Armishaw Christopher J; Daly Norelle L; Nevin Simon T; Adams David J; Craik David J; Alewood Paul F
Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.
The Journal of biological chemistry 2006;281(20):14136-43.
2006: Ireland David C; Colgrave Michelle L; Nguyencong Philip; Daly Norelle L; Craik David J
Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins.
Journal of molecular biology 2006;357(5):1522-35.
2006: Craik David J; Cemazar Masa; Daly Norelle L
The cyclotides and related macrocyclic peptides as scaffolds in drug design.
Current opinion in drug discovery & development 2006;9(2):251-60.
2006: Cemazar Masa; Daly Norelle L; Häggblad Sara; Lo Kai Pong; Yulyaningsih Ernie; Craik David J
Knots in rings. The circular knotted protein Momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate.
The Journal of biological chemistry 2006;281(12):8224-32.
2006: Craik David J
Chemistry. Seamless proteins tie up their loose ends.
Science (New York, N.Y.) 2006;311(5767):1563-4.
2006: Rosengren K Johan; Lin Feng; Bathgate Ross A D; Tregear Geoffrey W; Daly Norelle L; Wade John D; Craik David J
Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3.
The Journal of biological chemistry 2006;281(9):5845-51.
2006: Bansal Paramjit S; Grieve Paul A; Marschke Ronald J; Daly Norelle L; McGhie Emily; Craik David J; Alewood Paul F
Chemical synthesis and structure elucidation of bovine kappa-casein (1-44).
Biochemical and biophysical research communications 2006;340(4):1098-103.
2006: Clark Richard J; Daly Norelle L; Craik David J
Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.
The Biochemical journal 2006;394(Pt 1):85-93.
2006: Daly Norelle L; Clark Richard J; Plan Manuel R; Craik David J
Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif.
The Biochemical journal 2006;393(Pt 3):619-26.
2006: Chen Bin; Colgrave Michelle L; Wang Conan; Craik David J
Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae.
Journal of natural products 2006;69(1):23-8.
2006: Mulvenna Jason P; Wang Conan; Craik David J
CyBase: a database of cyclic protein sequence and structure.
Nucleic acids research 2006;34(Database issue):D192-4.
2006: Craik David
Peptides and therapeutic proteins--SRI conference. New opportunities for macromolecule development, delivery and commercialization. 17-18 November 2005, Philadelphia, PA, USA.
IDrugs : the investigational drugs journal 2006;9(1):25-7.
2006: Craik David J; Cemazar Masa; Wang Conan K L; Daly Norelle L
The cyclotide family of circular miniproteins: nature's combinatorial peptide template.
Biopolymers 2006;84(3):250-66.
2005: Simonsen Shane M; Sando Lillian; Ireland David C; Colgrave Michelle L; Bharathi Rekha; Göransson Ulf; Craik David J
A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae).
The Plant cell 2005;17(11):3176-89.
2005: Colgrave Michelle L; Jones Alun; Craik David J
Peptide quantification by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry: investigations of the cyclotide kalata B1 in biological fluids.
Journal of chromatography. A 2005;1091(1-2):187-93.
2005: Clark Richard J; Fischer Harald; Dempster Louise; Daly Norelle L; Rosengren K Johan; Nevin Simon T; Meunier Frederic A; Adams David J; Craik David J
Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):13767-72.
2005: Mulvenna Jason P; Foley Fiona M; Craik David J
Discovery, structural determination, and putative processing of the precursor protein that produces the cyclic trypsin inhibitor sunflower trypsin inhibitor 1.
The Journal of biological chemistry 2005;280(37):32245-53.
2005: Schirra Horst Joachim; Craik David J
Structure and folding of potato type II proteinase inhibitors: circular permutation and intramolecular domain swapping.
Protein and peptide letters 2005;12(5):421-31.
2005: Alewood Dianne; Nielsen Kathy; Alewood Paul F; Craik David J; Andrews Peter; Nerrie Maureen; White Sara; Domagala Teresa; Walker Francesca; Rothacker Julie; Burgess Antony W; Nice Edouard C
The role of disulfide bonds in the structure and function of murine epidermal growth factor (mEGF).
Growth factors (Chur, Switzerland) 2005;23(2):97-110.
2005: Chen Bin; Colgrave Michelle L; Daly Norelle L; Rosengren K Johan; Gustafson Kirk R; Craik David J
Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide.
The Journal of biological chemistry 2005;280(23):22395-405.
2005: Tregear Geoffrey W; Bathgate Ross A; Layfield Sharon; Ferraro Tania; Gundlach Andrew; Ma Sherie; Lin Feng; Hanson Nicola F; Summers Roger J; Rosengren Johan; Craik David J; Wade John D
The chemistry and biology of human relaxin-3.
Annals of the New York Academy of Sciences 2005;1041():40-6.
2005: Mulvenna Jason P; Sando Lillian; Craik David J
Processing of a 22 kDa precursor protein to produce the circular protein tricyclon A.
Structure (London, England : 1993) 2005;13(5):691-701.
2005: Craik David J; Daly Norelle L
Oxidative folding of the cystine knot motif in cyclotide proteins.
Protein and peptide letters 2005;12(2):147-52.
2005: Korsinczky Michael L J; Clark Richard J; Craik David J
Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1.
Biochemistry 2005;44(4):1145-53.
2005: Jennings Cameron V; Rosengren K Johan; Daly Norelle L; Plan Manuel; Stevens Jackie; Scanlon Martin J; Waine Clement; Norman David G; Anderson Marilyn A; Craik David J
Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?
Biochemistry 2005;44(3):851-60.
2005: Nilsson K Peter R; Lovelace Erica S; Caesar Christina E; Tynngård Nahreen; Alewood Paul F; Johansson Helena M; Sharpe Iain A; Lewis Richard J; Daly Norelle L; Craik David J
Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter.
Biopolymers 2005;80(6):815-23.
2004: Simonsen Shane M; Daly Norelle L; Craik David J
Capped acyclic permutants of the circular protein kalata B1.
FEBS letters 2004;577(3):399-402.
2004: Craik David J
European Peptide Society--28th Symposium and Third International Peptide Symposium. Peptides--bridges between disciplines. 5-10 September 2004, Prague, Czech Republic.
IDrugs : the investigational drugs journal 2004;7(11):992-3.
2004: Dutton Julie L; Renda Rosemary F; Waine Clement; Clark Richard J; Daly Norelle L; Jennings Cameron V; Anderson Marilyn A; Craik David J
Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins.
The Journal of biological chemistry 2004;279(45):46858-67.
2004: Korsinczky Michael L J; Schirra Horst Joachim; Craik David J
Sunflower trypsin inhibitor-1.
Current protein & peptide science 2004;5(5):351-64.
2004: Craik David J; Daly Norelle L; Mulvenna Jason; Plan Manuel R; Trabi Manuela
Discovery, structure and biological activities of the cyclotides.
Current protein & peptide science 2004;5(5):297-315.
2004: Salim Angela A; Garson Mary J; Craik David J
New indole alkaloids from the roots of Ochrosia acuminata.
Journal of natural products 2004;67(10):1719-21.
2004: Craik David
Drug Discovery Technology 2004--IBC's Ninth Annual World Congress. 8-13 August 2004, Boston, MA, USA.
IDrugs : the investigational drugs journal 2004;7(10):920-2.
2004: Maemoto Atsuo; Qu Xiaoqing; Rosengren K Johan; Tanabe Hiroki; Henschen-Edman Agnes; Craik David J; Ouellette Andre J
Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4.
The Journal of biological chemistry 2004;279(42):44188-96.
2004: Salim Angela A; Garson Mary J; Craik David J
New indole alkaloids from the bark of Alstonia scholaris.
Journal of natural products 2004;67(9):1591-4.
2004: Daly Norelle L; Gustafson Kirk R; Craik David J
The role of the cyclic peptide backbone in the anti-HIV activity of the cyclotide kalata B1.
FEBS letters 2004;574(1-3):69-72.
2004: Trabi Manuela; Craik David J
Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1.
The Plant cell 2004;16(8):2204-16.
2004: Millard Emma L; Daly Norelle L; Craik David J
Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors.
European journal of biochemistry / FEBS 2004;271(12):2320-6.
2004: Chiovitti Anthony; Bacic Antony; Craik David J; Kraft Gerald T; Liao Ming-Long
A nearly idealized 6'-O-methylated iota-carrageenan from the Australian red alga Claviclonium ovatum (Acrotylaceae, Gigartinales).
Carbohydrate research 2004;339(8):1459-66.
2004: Daly Norelle L; Ekberg Jenny A; Thomas Linda; Adams David J; Lewis Richard J; Craik David J
Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.
The Journal of biological chemistry 2004;279(24):25774-82.
2004: Trabi Manuela; Svangård Erika; Herrmann Anders; Göransson Ulf; Claeson Per; Craik David J; Bohlin Lars
Variations in cyclotide expression in viola species.
Journal of natural products 2004;67(5):806-10.
2004: Abuja Peter M; Zenz Alexandra; Trabi Manuela; Craik David J; Lohner Karl
The cyclic antimicrobial peptide RTD-1 induces stabilized lipid-peptide domains more efficiently than its open-chain analogue.
FEBS letters 2004;566(1-3):301-6.
2004: Colgrave Michelle L; Craik David J
Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.
Biochemistry 2004;43(20):5965-75.
2004: Rosengren K Johan; Blond Alain; Afonso Carlos; Tabet Jean-Claude; Rebuffat Sylvie; Craik David J
Structure of thermolysin cleaved microcin J25: extreme stability of a two-chain antimicrobial peptide devoid of covalent links.
Biochemistry 2004;43(16):4696-702.
2004: Salim Angela A; Garson Mary J; Craik David J
New alkaloids from Pandanus amaryllifolius.
Journal of natural products 2004;67(1):54-7.
2004: Barry Daniel G; Daly Norelle L; Bokesch Heidi R; Gustafson Kirk R; Craik David J
Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework.
Structure (London, England : 1993) 2004;12(1):85-94.
2004: Nourse Amanda; Trabi Manuela; Daly Norelle L; Craik David J
A comparison of the self-association behavior of the plant cyclotides kalata B1 and kalata B2 via analytical ultracentrifugation.
The Journal of biological chemistry 2004;279(1):562-70.
2004: Rosengren K Johan; Göransson Ulf; Otvos Laszlo; Craik David J
Cyclization of pyrrhocoricin retains structural elements crucial for the antimicrobial activity of the native peptide.
Biopolymers 2004;76(5):446-58.
2003: Göransson Ulf; Craik David J
Disulfide mapping of the cyclotide kalata B1. Chemical proof of the cystic cystine knot motif.
The Journal of biological chemistry 2003;278(48):48188-96.
2003: Rosengren K Johan; Clark Richard J; Daly Norelle L; Göransson Ulf; Jones Alun; Craik David J
Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone.
Journal of the American Chemical Society 2003;125(41):12464-74.
2003: Craik David
18th American Peptide Symposium. Peptide revolution: genomics, proteomics and therapeutics. 19-23 July 2003, Boston, MA, USA.
IDrugs : the investigational drugs journal 2003;6(9):855-7.
2003: Meutermans Wim D F; Bourne Gregory T; Golding Simon W; Horton Douglas A; Campitelli Marc R; Craik David; Scanlon Martin; Smythe Mark L
Difficult macrocyclizations: new strategies for synthesizing highly strained cyclic tetrapeptides.
Organic letters 2003;5(15):2711-4.
2003: Janssen Bert J C; Schirra Horst Joachim; Lay Fung T; Anderson Marilyn A; Craik David J
Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds.
Biochemistry 2003;42(27):8214-22.
2003: Craik David J; Daly Norelle L; Saska Ivana; Trabi Manuela; Rosengren K Johan
Structures of naturally occurring circular proteins from bacteria.
Journal of bacteriology 2003;185(14):4011-21.
2003: Barry Daniel G; Daly Norelle L; Clark Richard J; Sando Lillian; Craik David J
Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity.
Biochemistry 2003;42(22):6688-95.
2003: Marx Ute C; Korsinczky Michael L J; Schirra Horst Joachim; Jones Alun; Condie Barrie; Otvos Laszlo; Craik David J
Enzymatic cyclization of a potent bowman-birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide.
The Journal of biological chemistry 2003;278(24):21782-9.
2003: Blanchfield Joanne T; Dutton Julie L; Hogg Ronald C; Gallagher Oliver P; Craik David J; Jones Alun; Adams David J; Lewis Richard J; Alewood Paul F; Toth Istvan
Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII.
Journal of medicinal chemistry 2003;46(7):1266-72.
2003: Rosengren K Johan; Daly Norelle L; Plan Manuel R; Waine Clement; Craik David J
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework.
The Journal of biological chemistry 2003;278(10):8606-16.
2003: Daly Norelle L; Clark Richard J; Craik David J
Disulfide folding pathways of cystine knot proteins. Tying the knot within the circular backbone of the cyclotides.
The Journal of biological chemistry 2003;278(8):6314-22.
2003: Lay Fung T; Schirra Horst Joachim; Scanlon Martin J; Anderson Marilyn A; Craik David J
The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP.
Journal of molecular biology 2003;325(1):175-88.
2003: Nicke Annette; Loughnan Marion L; Millard Emma L; Alewood Paul F; Adams David J; Daly Norelle L; Craik David J; Lewis Richard J
Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence.
The Journal of biological chemistry 2003;278(5):3137-44.
2002: Dutton Julie L; Bansal Paramjit S; Hogg Ron C; Adams David J; Alewood Paul F; Craik David J
A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity.
The Journal of biological chemistry 2002;277(50):48849-57.
2002: Craik David
Venoms to Drugs 2002 Conference.
IDrugs : the investigational drugs journal 2002;5(9):881-4.
2002: Nielsen Katherine J; Watson Michael; Adams David J; Hammarström Anna K; Gage Peter W; Hill Justine M; Craik David J; Thomas Linda; Adams Denise; Alewood Paul F; Lewis Richard J
Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels.
The Journal of biological chemistry 2002;277(30):27247-55.
2002: Craik David J; Simonsen Shane; Daly Norelle L
The cyclotides: novel macrocyclic peptides as scaffolds in drug design.
Current opinion in drug discovery & development 2002;5(2):251-60.
2002: Trabi Manuela; Craik David J
Circular proteins--no end in sight.
Trends in biochemical sciences 2002;27(3):132-8.
2002: Rosengren K Johan; Wilson David; Daly Norelle L; Alewood Paul F; Craik David J
Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds.
Biochemistry 2002;41(10):3294-301.
2001: Craik D J
Plant cyclotides: circular, knotted peptide toxins.
Toxicon : official journal of the International Society on Toxinology 2001;39(12):1809-13.
2001: Craik D
Peptide--Fourth Australian Conference. From discovery to therapeutics--the new millennium.
IDrugs : the investigational drugs journal 2001;4(11):1263-5.
2001: Jennings C; West J; Waine C; Craik D; Anderson M
Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10614-9.
2001: Sharpe I A; Gehrmann J; Loughnan M L; Thomas L; Adams D A; Atkins A; Palant E; Craik D J; Adams D J; Alewood P F; Lewis R J
Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nature neuroscience 2001;4(9):902-7.
2001: Korsinczky M L; Schirra H J; Rosengren K J; West J; Condie B A; Otvos L; Anderson M A; Craik D J
Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant.
Journal of molecular biology 2001;311(3):579-91.
2001: Felizmenio-Quimio M E; Daly N L; Craik D J
Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis.
The Journal of biological chemistry 2001;276(25):22875-82.
2001: Rosengren K J; Daly N L; Scanlon M J; Craik D J
Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina.
Biochemistry 2001;40(15):4601-9.
2001: Trabi M; Schirra H J; Craik D J
Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes.
Biochemistry 2001;40(14):4211-21.
2001: Dutton J L; Craik D J
alpha-Conotoxins: nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leads.
Current medicinal chemistry 2001;8(4):327-44.
2001: Schirra H J; Scanlon M J; Lee M C; Anderson M A; Craik D J
The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata.
Journal of molecular biology 2001;306(1):69-79.
2001: Craik D J; Daly N L; Waine C
The cystine knot motif in toxins and implications for drug design.
Toxicon : official journal of the International Society on Toxinology 2001;39(1):43-60.
2000: McManus A M; Dawson N F; Wade J D; Carrington L E; Winzor D J; Craik D J
Three-dimensional structure of RK-1: a novel alpha-defensin peptide.
Biochemistry 2000;39(51):15757-64.
2000: Lewis R J; Nielsen K J; Craik D J; Loughnan M L; Adams D A; Sharpe I A; Luchian T; Adams D J; Bond T; Thomas L; Jones A; Matheson J L; Drinkwater R; Andrews P R; Alewood P F
Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes.
The Journal of biological chemistry 2000;275(45):35335-44.
2000: Daly N L; Hoffmann R; Otvos L; Craik D J
Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease.
Biochemistry 2000;39(30):9039-46.
2000: Hill J M; Alewood P F; Craik D J
Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 2. Three-dimensional solution structure.
European journal of biochemistry / FEBS 2000;267(15):4649-57.
2000: Hill J M; Atkins A R; Loughnan M L; Jones A; Adams D A; Martin R C; Lewis R J; Craik D J; Alewood P F
Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 1. Isolation, characterization and chemical synthesis.
European journal of biochemistry / FEBS 2000;267(15):4642-8.
2000: Poulsen S A; Watson A A; Fairlie D P; Craik D J
Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F).
Journal of structural biology 2000;130(2-3):142-52.
2000: Daly N L; Craik D J
Acyclic permutants of naturally occurring cyclic proteins. Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1.
The Journal of biological chemistry 2000;275(25):19068-75.
2000: Abbenante G; Kovacs D M; Leung D L; Craik D J; Tanzi R E; Fairlie D P
Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site.
Biochemical and biophysical research communications 2000;268(1):133-5.
2000: Dawson N F; Craik D J; McManus A M; Dashper S G; Reynolds E C; Tregear G W; Otvos L; Wade J D
Chemical synthesis, characterization and activity of RK-1, a novel alpha-defensin-related peptide.
Journal of peptide science : an official publication of the European Peptide Society 2000;6(1):19-25.
1999: Craik D J
The chemistry-medicine continuum.
IDrugs : the investigational drugs journal 1999;2(12):1283-4.
1999: Craik D J; Daly N L; Bond T; Waine C
Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.
Journal of molecular biology 1999;294(5):1327-36.
1999: Hogg R C; Miranda L P; Craik D J; Lewis R J; Alewood P F; Adams D J
Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor.
The Journal of biological chemistry 1999;274(51):36559-64.
1999: Pavlopoulos S; Bicknell W; Wickham G; Craik D J
Characterization of the sequential non-covalent and covalent interactions of the antitumour antibiotic hedamycin with double stranded DNA by NMR spectroscopy.
Journal of molecular recognition : JMR 1999;12(6):346-54.
1999: McManus A M; Nielsen K J; Marcus J P; Harrison S J; Green J L; Manners J M; Craik D J
MiAMP1, a novel protein from Macadamia integrifolia adopts a Greek key beta-barrel fold unique amongst plant antimicrobial proteins.
Journal of molecular biology 1999;293(3):629-38.
1999: Daly N L; Love S; Alewood P F; Craik D J
Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.
Biochemistry 1999;38(32):10606-14.
1999: Scanlon M J; Lee M C; Anderson M A; Craik D J
Structure of a putative ancestral protein encoded by a single sequence repeat from a multidomain proteinase inhibitor gene from Nicotiana alata.
Structure (London, England : 1993) 1999;7(7):793-802.
1999: Gehrmann J; Daly N L; Alewood P F; Craik D J
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance.
Journal of medicinal chemistry 1999;42(13):2364-72.
1999: Nielsen K J; Adams D; Thomas L; Bond T; Alewood P F; Craik D J; Lewis R J
Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels.
Journal of molecular biology 1999;289(5):1405-21.
1999: Lee M C; Scanlon M J; Craik D J; Anderson M A
A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein.
Nature structural biology 1999;6(6):526-30.
1999: Finch A M; Wong A K; Paczkowski N J; Wadi S K; Craik D J; Fairlie D P; Taylor S M
Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a.
Journal of medicinal chemistry 1999;42(11):1965-74.
1999: Nielsen K J; Adams D A; Alewood P F; Lewis R J; Thomas L; Schroeder T; Craik D J
Effects of chirality at Tyr13 on the structure-activity relationships of omega-conotoxins from Conus magus.
Biochemistry 1999;38(21):6741-51.
1999: Harrison S J; McManus A M; Marcus J P; Goulter K C; Green J L; Nielsen K J; Craik D J; Maclean D J; Manners J M
Purification and characterization of a plant antimicrobial peptide expressed in Escherichia coli.
Protein expression and purification 1999;15(2):171-7.
1999: Nielsen K J; Skjaerbaek N; Dooley M; Adams D A; Mortensen M; Dodd P R; Craik D J; Alewood P F; Lewis R J
Structure-activity studies of conantokins as human N-methyl-D-aspartate receptor modulators.
Journal of medicinal chemistry 1999;42(3):415-26.
1999: McManus A M; Otvos L; Hoffmann R; Craik D J
Conformational studies by NMR of the antimicrobial peptide, drosocin, and its non-glycosylated derivative: effects of glycosylation on solution conformation.
Biochemistry 1999;38(2):705-14.
1999: Daly N L; Koltay A; Gustafson K R; Boyd M R; Casas-Finet J R; Craik D J
Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity.
Journal of molecular biology 1999;285(1):333-45.
1998: Hill J M; Oomen C J; Miranda L P; Bingham J P; Alewood P F; Craik D J
Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity.
Biochemistry 1998;37(45):15621-30.
1998: Watson A A; Fairlie D P; Craik D J
Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?
Biochemistry 1998;37(37):12700-6.
1998: Wong A K; Finch A M; Pierens G K; Craik D J; Taylor S M; Fairlie D P
Small molecular probes for G-protein-coupled C5a receptors: conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a.
Journal of medicinal chemistry 1998;41(18):3417-25.
1998: Coles M; Bicknell W; Watson A A; Fairlie D P; Craik D J
Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
Biochemistry 1998;37(31):11064-77.
1998: Ilg T; Craik D; Currie G; Multhaup G; Bacic A
Stage-specific proteophosphoglycan from Leishmania mexicana amastigotes. Structural characterization of novel mono-, di-, and triphosphorylated phosphodiester-linked oligosaccharides.
The Journal of biological chemistry 1998;273(22):13509-23.
1998: Gehrmann J; Alewood P F; Craik D J
Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability.
Journal of molecular biology 1998;278(2):401-15.
1997: Scanlon M J; Naranjo D; Thomas L; Alewood P F; Lewis R J; Craik D J
Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA.
Structure (London, England : 1993) 1997;5(12):1585-97.
1997: Najbar L V; Craik D J; Wade J D; Salvatore D; McLeish M J
Conformational analysis of LYS(11-36), a peptide derived from the beta-sheet region of T4 lysozyme, in TFE and SDS.
Biochemistry 1997;36(38):11525-33.
1997: Hu S H; Gehrmann J; Alewood P F; Craik D J; Martin J L
Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI.
Biochemistry 1997;36(38):11323-30.
1997: Sims I M; Craik D J; Bacic A
Structural characterisation of galactoglucomannan secreted by suspension-cultured cells of Nicotiana plumbaginifolia.
Carbohydrate research 1997;303(1):79-92.
1997: Duggan B M; Craik D J
Conformational dynamics of thyroid hormones by variable temperature nuclear magnetic resonance: the role of side chain rotations and cisoid/transoid interconversions.
Journal of medicinal chemistry 1997;40(14):2259-65.
1997: Hill J M; Alewood P F; Craik D J
Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry.
Structure (London, England : 1993) 1997;5(4):571-83.
1997: Skjaerbaek N; Nielsen K J; Lewis R J; Alewood P; Craik D J
Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
The Journal of biological chemistry 1997;272(4):2291-9.
1997: Craik D J; Wilce J A
Studies of protein-ligand interactions by NMR.
Methods in molecular biology (Clifton, N.J.) 1997;60():195-232.
1996: Liao M L; Chiovitti A; Munro S L; Craik D J; Kraft G T; Bacic A
Sulfated galactans from Australian specimens of the red alga Phacelocarpus peperocarpos (Gigartinales, Rhodophyta).
Carbohydrate research 1996;296():237-47.
1996: Sims I M; Munro S L; Currie G; Craik D; Bacic A
Structural characterisation of xyloglucan secreted by suspension-cultured cells of Nicotiana plumbaginifolia.
Carbohydrate research 1996;293(2):147-72.
1996: Nielsen K J; Thomas L; Lewis R J; Alewood P F; Craik D J
A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
Journal of molecular biology 1996;263(2):297-310.
1996: Oxley D; Munro S L; Craik D J; Bacic A
Structure of N-glycans on the S3- and S6-allele stylar self-incompatibility ribonucleases of Nicotiana alata.
Glycobiology 1996;6(6):611-8.
1996: Duggan B M; Craik D J
1H and 13C NMR relaxation studies of molecular dynamics of the thyroid hormones thyroxine, 3,5,3'-triiodothyronine, and 3,5-diiodothyronine.
Journal of medicinal chemistry 1996;39(20):4007-16.
1996: Pavlopoulos S; Bicknell W; Craik D J; Wickham G
Structural characterization of the 1:1 adduct formed between the antitumor antibiotic hedamycin and the oligonucleotide duplex d(CACGTG)2 by 2D NMR spectroscopy.
Biochemistry 1996;35(29):9314-24.
1996: Hill J M; Alewood P F; Craik D J
Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels.
Biochemistry 1996;35(27):8824-35.
1996: Hu S H; Gehrmann J; Guddat L W; Alewood P F; Craik D J; Martin J L
The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus.
Structure (London, England : 1993) 1996;4(4):417-23.
1996: Nielsen K J; Hill J M; Anderson M A; Craik D J
Synthesis and structure determination by NMR of a putative vacuolar targeting peptide and model of a proteinase inhibitor from Nicotiana alata.
Biochemistry 1996;35(2):369-78.
1996: Wilce J A; Otvos L; Craik D J
1H NMR studies of the effects of glycosylation on the C-terminal pentapeptide of peptide T.
Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity 1996;2(2):59-66.
1996: Wilce J A; Zeng W; Rose K; Craik D J; Jackson D C
1H NMR structural study of free and template-linked antigenic peptide representing the C-terminal region of the heavy chain of influenza virus hemagglutinin.
Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity 1996;2(2):51-8.
1995: Pavlopoulos S; Rose M; Wickham G; Craik D J
A 1H NMR analysis of the interaction between terephthalamide derivatives and the oligonucleotide duplex d(GGTAATTACC)2.
Anti-cancer drug design 1995;10(8):623-39.
1995: Hawkins B; Cross K; Craik D
Solution structure of the B-chain of insulin as determined by 1H NMR spectroscopy. Comparison with the crystal structure of the insulin hexamer and with the solution structure of the insulin monomer.
International journal of peptide and protein research 1995;46(5):424-33.
1995: Gane A M; Craik D; Munro S L; Howlett G J; Clarke A E; Bacic A
Structural analysis of the carbohydrate moiety of arabinogalactan-proteins from stigmas and styles of Nicotiana alata.
Carbohydrate research 1995;277(1):67-85.
1995: Nielsen K J; Heath R L; Anderson M A; Craik D J
Structures of a series of 6-kDa trypsin inhibitors isolated from the stigma of Nicotiana alata.
Biochemistry 1995;34(44):14304-11.
1995: Puanglarp N; Oxley D; Currie G J; Bacic A; Craik D J; Yellowlees D
Structure of the N-linked oligosaccharides from tridacnin, a lectin found in the haemolymph of the giant clam Hippopus hippopus.
European journal of biochemistry / FEBS 1995;232(3):873-80.
1995: Wilce J A; Craik D J; Ede N; Jackson D C; Schreiber G
1H NMR studies of peptide fragments from the N-terminus of chicken and human transthyretin.
Biochemistry and molecular biology international 1995;36(6):1153-9.
1995: Najbar L V; Craik D J; Wade J D; Lin F; McLeish M J
CD and NMR determination of the solution structure of a peptide corresponding to T4 lysozyme residues 38-51.
Biochimica et biophysica acta 1995;1250(2):163-70.
1995: Scanlon M J; Fairlie D P; Craik D J; Englebretsen D R; West M L
NMR solution structure of the RNA-binding peptide from human immunodeficiency virus (type 1) Rev.
Biochemistry 1995;34(26):8242-9.
1995: Jarvis J A; Craik D J
13C NMR relaxation studies of molecular motion in peptide fragments from human transthyretin.
Journal of magnetic resonance. Series B 1995;107(2):95-106.
1995: Shehan B P; Wellard R M; Craik D J; Adam W R
133Cs relaxation times in rat tissues.
Journal of magnetic resonance. Series B 1995;107(2):179-85.
1995: Jarvis J A; Ryan M T; Hoogenraad N J; Craik D J; Høj P B
Solution structure of the acetylated and noncleavable mitochondrial targeting signal of rat chaperonin 10.
The Journal of biological chemistry 1995;270(3):1323-31.
1994: Hawkins B L; Cross K J; Craik D J
A 1H-NMR determination of the solution structure of the A-chain of insulin: comparison with the crystal structure and an examination of the role of solvent.
Biochimica et biophysica acta 1994;1209(2):177-82.
1994: Nicholls I A; Craik D J; Alewood P F
NMR and molecular modelling based conformational analysis of some N-alkyl 1- and 2-benzazepinones: useful central nervous system agent design motifs.
Biochemical and biophysical research communications 1994;205(1):98-104.
1994: Jarvis J A; Kirkpatrick A; Craik D J
1H NMR analysis of fibril-forming peptide fragments of transthyretin.
International journal of peptide and protein research 1994;44(4):388-98.
1994: Pallaghy P K; Nielsen K J; Craik D J; Norton R S
A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides.
Protein science : a publication of the Protein Society 1994;3(10):1833-9.
1994: Nielsen K J; Heath R L; Anderson M A; Craik D J
The three-dimensional solution structure by 1H NMR of a 6-kDa proteinase inhibitor isolated from the stigma of Nicotiana alata.
Journal of molecular biology 1994;242(3):231-43.
1994: McLeish M J; Nielsen K J; Najbar L V; Wade J D; Lin F; Doughty M B; Craik D J
Conformation of a peptide corresponding to T4 lysozyme residues 59-81 by NMR and CD spectroscopy.
Biochemistry 1994;33(37):11174-83.
1994: Wellard R M; Shehan B P; Craik D J; Adam W R
Factors affecting 133Cs chemical shifts in erythrocytes from cesium-fed rats.
Journal of magnetic resonance. Series B 1994;104(3):276-9.
1994: Wilson J C; Nielsen K J; McLeish M J; Craik D J
A determination of the solution conformation of the nonmammalian tachykinin eledoisin by NMR and CD spectroscopy.
Biochemistry 1994;33(22):6802-11.
1994: Sowemimo V; Scanlon D; Jones P; Craik D J
Synthesis of cyclic penta- and hexapeptides: a general synthetic strategy on DAS resin.
Journal of protein chemistry 1994;13(3):339-46.
1994: Coles M; Munro S L; Craik D J
The solution structure of a monocyclic analogue of endothelin [1,15 Aba]-ET-1, determined by 1H NMR spectroscopy.
Journal of medicinal chemistry 1994;37(5):656-64.
1994: Nielsen K J; Alewood D; Andrews J; Kent S B; Craik D J
An 1H NMR determination of the three-dimensional structures of mirror-image forms of a Leu-5 variant of the trypsin inhibitor from Ecballium elaterium (EETI-II).
Protein science : a publication of the Protein Society 1994;3(2):291-302.
1994: Sorimachi K; Craik D J
Structure determination of extracellular fragments of amyloid proteins involved in Alzheimer's disease and Dutch-type hereditary cerebral haemorrhage with amyloidosis.
European journal of biochemistry / FEBS 1994;219(1-2):237-51.
1994: Jarvis J A; Munro S L; Craik D J
Structural analysis of peptide fragment 71-93 of transthyretin by NMR spectroscopy and electron microscopy: insight into amyloid fibril formation.
Biochemistry 1994;33(1):33-41.
1993: Shehan B P; Wellard R M; Adam W R; Craik D J
The use of dietary loading of 133Cs as a potassium substitute in NMR studies of tissues.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1993;30(5):573-82.
1993: Coles M; Sowemimo V; Scanlon D; Munro S L; Craik D J
A conformational study by 1H NMR of a cyclic pentapeptide antagonist of endothelin.
Journal of medicinal chemistry 1993;36(18):2658-65.
1993: Horne J; Sadek M; Craik D J
Determination of the solution structure of neuropeptide K by high-resolution nuclear magnetic resonance spectroscopy.
Biochemistry 1993;32(29):7406-12.
1993: Jarvis J A; Craik D J; Wilce M C
X-ray diffraction studies of fibrils formed from peptide fragments of transthyretin.
Biochemical and biophysical research communications 1993;192(3):991-8.
1993: Chalmers D K; Scholz G H; Topliss D J; Kolliniatis E; Munro S L; Craik D J; Iskander M N; Stockigt J R
Thyroid hormone uptake by hepatocytes: structure-activity relationships of phenylanthranilic acids with inhibitory activity.
Journal of medicinal chemistry 1993;36(9):1272-7.
1993: Embrey K J; Searle M S; Craik D J
Interaction of Hoechst 33258 with the minor groove of the A + T-rich DNA duplex d(GGTAATTACC)2 studied in solution by NMR spectroscopy.
European journal of biochemistry / FEBS 1993;211(3):437-47.
1993: McLeish M J; Nielsen K J; Wade J D; Craik D J
A peptide corresponding to the N-terminal 13 residues of T4 lysozyme forms an alpha-helix.
FEBS letters 1993;315(3):323-8.
1993: Wellard R M; Shehan B P; Adam W R; Craik D J
NMR measurement of 39K detectability and relaxation constants in rat tissue.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1993;29(1):68-76.
1992: Moloney G P; Craik D J; Iskander M N
Qualitative analysis of the stability of the oxazine ring of various benzoxazine and pyridooxazine derivatives with proton nuclear magnetic resonance spectroscopy.
Journal of pharmaceutical sciences 1992;81(7):692-7.
1992: Woodward J R; Craik D; Dell A; Khoo K H; Munro S L; Clarke A E; Bacic A
Structural analysis of the N-linked glycan chains from a stylar glycoprotein associated with expression of self-incompatibility in Nicotiana alata.
Glycobiology 1992;2(3):241-50.
1992: Chalmers D K; Munro S L; Iskander M N; Craik D J
Models for the binding of amiodarone to the thyroid hormone receptor.
Journal of computer-aided molecular design 1992;6(1):19-31.
1992: Hasin Y; Kneen M M; Craik D J; Nayler W G
Relationship between ATP resynthesis and calcium accumulation in the reperfused rat heart.
Clinical and experimental pharmacology & physiology 1992;19(2):79-87.
1992: Jarvis J A; Munro S L; Craik D J
Homology model of thyroxine binding globulin and elucidation of the thyroid hormone binding site.
Protein engineering 1992;5(1):61-7.
1991: Craik D; Munro S; Nielsen K; Shehan P; Tregear G; Wade J
The conformation of porcine-brain natriuretic peptide by two-dimensional NMR spectroscopy.
European journal of biochemistry / FEBS 1991;201(1):183-90.
1991: Nielsen K J; Barron P R; Craik D J; Lambert P F; Wade J D
Two-dimensional nuclear magnetic resonance study of brain natriuretic peptide in aqueous solution.
Biochemistry international 1991;25(2):199-210.
1991: Casarotto M G; Craik D J; Lloyd E J
NMR studies of the conformational interconversion of butaclamol in solution.
Journal of medicinal chemistry 1991;34(7):2043-9.
1991: Casarotto M G; Craik D J; Lloyd E J; Partridge A C
An NMR and theoretical study of the conformation and internal flexibility of butaclamol hydrochloride.
Journal of medicinal chemistry 1991;34(7):2036-43.
1991: Embrey K J; Searle M S; Craik D J
Structural analysis of the decanucleotide duplex d(GGTAATTACC)2 using 1H NMR spectroscopy.
Biochemistry international 1991;24(3):567-76.
1991: Craik D J; Higgins K A
Comparison of 1H NMR chemical shifts of bovine and human insulins.
Peptide research 1991;4(3):177-86.
1991: Rashid S A; Adam W R; Craik D J; Shehan B P; Wellard R M
Factors affecting 39K NMR detectability in rat tissue.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;17(1):213-24.
1991: Munro S; Craik D; McConville C; Hall J; Searle M; Bicknell W; Scanlon D; Chandler C
Solution conformation of endothelin, a potent vaso-constricting bicyclic peptide. A combined use of 1H NMR spectroscopy and distance geometry calculations.
FEBS letters 1991;278(1):9-13.
1990: Higgins K A; Craik D J; Hall J G
2D 1H NMR studies of monomeric insulin.
Biochemistry international 1990;22(4):627-37.
1990: Sorimachi K; Craik D J; Lloyd E J; Beyreuther K; Masters C L
Identification of a beta-turn in the tertiary structure of a peptide fragment of the Alzheimer amyloid protein.
Biochemistry international 1990;22(3):447-54.
1990: Sadek M; Craik D J; Hall J G; Andrews P R
Conformational analysis of cyproheptadine hydrochloride.
Journal of medicinal chemistry 1990;33(4):1098-107.
1989: Adam W R; Craik D J; Kneen M; Wellard R M
Effect of magnesium depletion and potassium depletion and chlorothiazide on intracellular pH in the rat, studied by 31P NMR.
Clinical and experimental pharmacology & physiology 1989;16(1):33-40.
1988: Adam W R; Craik D J; Hall J G; Kneen M M; Wellard R M
Problems in the assessment of magnesium depletion in the rat by in vivo 31P NMR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1988;7(3):300-10.
1988: Higgins K A; Craik D J; Hall J G; Andrews P R
Cis-trans isomerization of the proline residue in insulin studied by 13C NMR spectroscopy.
Drug design and delivery 1988;3(2):159-70.
1987: Craik D J; Hall J G; Higgins K A
C-13 NMR spectral studies of the thyroid hormone transport protein, transthyretin and the pancreatic insulin storage moiety, the zinc-insulin hexamer.
Biochemical and biophysical research communications 1987;143(1):116-25.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

David Craik

Research Profile (preview)

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Phenomena

Procedures

Physiology

Living Beings

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of David Craik (preview)

All Publications