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Sean Cregan

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Disorders

DNA Damage

Physiology

Cell Death

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Publications

TOP 3
Zohreh Galehdar; Patrick Swan; Benjamin Fuerth; Steven M Callaghan; David Park; Sean P Cregan
Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA.
Yi Zhang; Mohammad Parsanejad; En Huang; Dianbo Qu; Hossein Aleyasin; Rousseaux Maxime; Yasmilde Rodriguez Gonzalez; Sean P Cregan; ruth slack; David Park
Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage.
Eric C C Cheung; Lysanne Melanson-Drapeau; Sean P Cregan; Jacqueline L Vanderluit; Kerry L Ferguson; William C McIntosh; David Park; Steffany A L Bennett; ruth slack
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.

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All Publications

2010: Zohreh Galehdar; Patrick Swan; Benjamin Fuerth; Steven M Callaghan; David Park; Sean P Cregan
Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(50):16938-48.
2010: Yi Zhang; Mohammad Parsanejad; En Huang; Dianbo Qu; Hossein Aleyasin; Rousseaux Maxime; Yasmilde Rodriguez Gonzalez; Sean P Cregan; ruth slack; David Park
Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage.
Journal of neurochemistry 2010;112(2):497-510.
2005: Eric C C Cheung; Lysanne Melanson-Drapeau; Sean P Cregan; Jacqueline L Vanderluit; Kerry L Ferguson; William C McIntosh; David Park; Steffany A L Bennett; ruth slack
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(6):1324-34.
2004: Sean P Cregan; Nicole A Arbour; Jason G MacLaurin; Steven M Callaghan; Andre Fortin; Eric C C Cheung; Daniel S Guberman; David Park; ruth slack
p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(44):10003-12.
2004: Andre Fortin; Jason G MacLaurin; Nicole Arbour; Sean P Cregan; Neena Kushwaha; Steven M Callaghan; David Park; Paul R Albert; ruth slack
The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1.
The Journal of biological chemistry 2004;279(27):28706-14.
2004: Sean P Cregan; Valina Dawson; ruth slack
Role of AIF in caspase-dependent and caspase-independent cell death.
Oncogene 2004;23(16):2785-96.
2004: Hossein Aleyasin; Sean P Cregan; Grace Iyirhiaro; Michael J O'Hare; Steven M Callaghan; ruth slack; David Park
Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(12):2963-73.
2002: Sean P Cregan; Andre Fortin; Jason G MacLaurin; Steven M Callaghan; Francesco Cecconi; Seong-Woon Yu; Ted M Dawson; Valina Dawson; David Park; Guido Kroemer; ruth slack
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death.
The Journal of cell biology 2002;158(3):507-17.
2001: Andre Fortin; Sean P Cregan; Jason G MacLaurin; Neena Kushwaha; Emma S Hickman; C S Thompson; A Hakim; Paul R Albert; Francesco Cecconi; Kristian Helin; David Park; ruth slack
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.
The Journal of cell biology 2001;155(2):207-16.
2000: Michael J O'Hare; Sheng T Hou; Erick Morris; Sean P Cregan; Q Xu; ruth slack; David Park
Induction and modulation of cerebellar granule neuron death by E2F-1.
The Journal of biological chemistry 2000;275(33):25358-64.
2000: Sean P Cregan; Jason G MacLaurin; Tania F Gendron; Steven M Callaghan; David Park; Robin J Parks; Frank L Graham; Paul Morley; ruth slack
Helper-dependent adenovirus vectors: their use as a gene delivery system to neurons.
Gene therapy 2000;7(14):1200-9.
1999: Sean P Cregan; Jason G MacLaurin; C G Craig; George S Robertson; Donald W Nicholson; David Park; ruth slack
Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(18):7860-9.