FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Piero Crespo

Research Profile

Physiology

Chemicals & Drugs

Living Beings

Mouse

Phenomena

Phosphorylation

Anatomy

Co-author Network

Publications

TOP 3
Fernando Calvo; Lorena Agudo-Ibáñez; Christopher J Marshall; Erik Sahai; Victoria Sanz-Moreno; Fredrik Wallberg; Piero Crespo
RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation.
Imanol Arozarena; Fernando Calvo; Piero Crespo
Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.
Javier Rodríguez; Piero Crespo
Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Piero Crespo (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Fernando Calvo; Lorena Agudo-Ibáñez; Christopher J Marshall; Erik Sahai; Victoria Sanz-Moreno; Fredrik Wallberg; Piero Crespo
RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation.
Nature cell biology 2011;13(7):819-26.
2011: Imanol Arozarena; Fernando Calvo; Piero Crespo
Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.
Genes & cancer 2011;2(3):182-94.
2011: Javier Rodríguez; Piero Crespo
Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases.
Science signaling 2011;4(196):re3.
2010: David Matallanas; Piero Crespo
New druggable targets in the Ras pathway?
Current opinion in molecular therapeutics 2010;12(6):674-83.
2010: Javier Rodríguez; Fernando Calvo; José M González; Berta CASAR; Vicente Andrés; Piero Crespo
ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.
The Journal of cell biology 2010;191(5):967-79.
2010: Fernando Calvo; Lorena Agudo-Ibáñez; Piero Crespo
The Ras-ERK pathway: understanding site-specific signaling provides hope of new anti-tumor therapies.
BioEssays : news and reviews in molecular, cellular and developmental biology 2010;32(5):412-21.
2010: Adán Pinto; Piero Crespo
Analysis of ERKs' dimerization by electrophoresis.
Methods in molecular biology (Clifton, N.J.) 2010;661():335-42.
2010: Mario Chiariello; Jose P Vaqué; Piero Crespo; J Silvio Gutkind
Activation of Ras and Rho GTPases and MAP Kinases by G-protein-coupled receptors.
Methods in molecular biology (Clifton, N.J.) 2010;661():137-50.
2009: Fernando Calvo; Piero Crespo
Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors.
Molecular biology of the cell 2009;20(20):4289-302.
2009: Berta CASAR; Adán Pinto; Piero Crespo
ERK dimers and scaffold proteins: unexpected partners for a forgotten (cytoplasmic) task.
Cell cycle (Georgetown, Tex.) 2009;8(7):1007-13.
2009: Berta CASAR; Imanol Arozarena; Victoria Sanz-Moreno; Adán Pinto; Lorena Agudo-Ibáñez; Richard Marais; Robert Lewis; María T Berciano; Piero Crespo
Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins.
Molecular and cellular biology 2009;29(5):1338-53.
2008: Berta CASAR; Adán Pinto; Piero Crespo
Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes.
Molecular cell 2008;31(5):708-21.
2008: José P Vaqué; Belén Fernández-García; Pablo García-Sanz; Nuria Ferrandiz; Gabriel Bretones; Fernando Calvo; Piero Crespo; María C Marín; Javier León
c-Myc inhibits Ras-mediated differentiation of pheochromocytoma cells by blocking c-Jun up-regulation.
Molecular cancer research : MCR 2008;6(2):325-39.
2007: Lorena Agudo-Ibáñez; Fátima Núñez; Fernando Calvo; Inmaculada M Berenjeno; Xose Bustelo; Piero Crespo
Transcriptomal profiling of site-specific Ras signals.
Cellular signalling 2007;19(11):2264-76.
2007: Susana E Martínez; Francisco Lázaro-Diéguez; Javier Selva; Fernando Calvo; Jaime-Renau Piqueras; Piero Crespo; Enrique Claro; Gustavo Egea
Lysophosphatidic acid rescues RhoA activation and phosphoinositides levels in astrocytes exposed to ethanol.
Journal of neurochemistry 2007;102(4):1044-52.
2007: Berta CASAR; Victoria Sanz-Moreno; Mustafa Yazicioglu; Javier Rodríguez; María T Berciano; Miguel Lafarga; Melanie H Cobb; Piero Crespo
Mxi2 promotes stimulus-independent ERK nuclear translocation.
The EMBO journal 2007;26(3):635-46.
2006: Sandra Peregrin; María Jurado-Pueyo; Pedro M Campos; Victoria Sanz-Moreno; Ana Ruiz-Gomez; Piero Crespo; Federico Mayor; Cristina Murga
Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK.
Current biology : CB 2006;16(20):2042-7.
2006: David Matallanas; Victoria Sanz-Moreno; Imanol Arozarena; Fernando Calvo; Lorena Agudo-Ibáñez; Eugenio Santos; María T Berciano; Piero Crespo
Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation.
Molecular and cellular biology 2006;26(1):100-16.
2005: Jose P Vaqué; Joaquin Navascues; Yuzuru Shiio; Marikki Laiho; Nuria Ajenjo; Itsaso Mauleon; David Matallanas; Piero Crespo; Javier León
Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway.
The Journal of biological chemistry 2005;280(2):1112-22.
2004: Nuria Ajenjo; Estela Cañón; Isabel Sánchez-Pérez; David Matallanas; Javier León; Rosario Perona; Piero Crespo
Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells.
The Journal of biological chemistry 2004;279(31):32813-23.
2004: Imanol Arozarena; David Matallanas; María T Berciano; Victoria Sanz-Moreno; Fernando Calvo; María T Muñoz; Gustavo Egea; Miguel Lafarga; Piero Crespo
Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors.
Molecular and cellular biology 2004;24(4):1516-30.
2004: Pierfrancesco Vargiu; Ricardo De Abajo; Juan Antonio Garcia-Ranea; Alfonso Valencia; Pilar Santisteban; Piero Crespo; Juan Bernal
The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors.
Oncogene 2004;23(2):559-68.
2003: María J Caloca; José L Zugaza; David Matallanas; Piero Crespo; Xose Bustelo
Vav mediates Ras stimulation by direct activation of the GDP/GTP exchange factor Ras GRP1.
The EMBO journal 2003;22(13):3326-36.
2003: Victoria Sanz-Moreno; Berta CASAR; Piero Crespo
p38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levels.
Molecular and cellular biology 2003;23(9):3079-90.
2003: David Matallanas; Imanol Arozarena; María T Berciano; David S Aaronson; Angel Pellicer; Miguel Lafarga; Piero Crespo
Differences on the inhibitory specificities of H-Ras, K-Ras, and N-Ras (N17) dominant negative mutants are related to their membrane microlocalization.
The Journal of biological chemistry 2003;278(7):4572-81.
2002: Xose Bustelo; Piero Crespo
Walking pathways at Heidelberg. Conference on oncogenes and growth control.
EMBO reports 2002;3(11):1023-8.
2002: Azucena Esparís-Ogando; Elena Diaz-Rodriguez; Juan Carlos Montero; Laura Yuste; Piero Crespo; Atanasio Pandiella
Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2.
Molecular and cellular biology 2002;22(1):270-85.
2001: Imanol Arozarena; David Matallanas; Piero Crespo
Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP.
The Journal of biological chemistry 2001;276(24):21878-84.
2000: Imanol Arozarena; David S Aaronson; David Matallanas; V Sanz; Nuria Ajenjo; S P Tenbaum; Hidemi Teramoto; T Ighishi; Juan Carlos Zabala; J Silvio Gutkind; Piero Crespo
The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF.
The Journal of biological chemistry 2000;275(34):26441-8.
2000: V Sanz; Imanol Arozarena; Piero Crespo
Distinct carboxy-termini confer divergent characteristics to the mitogen-activated protein kinase p38alpha and its splice isoform Mxi2.
FEBS letters 2000;474(2-3):169-74.
2000: Emma Pena; María T Berciano; Rosario Fernandez; Piero Crespo; Miguel Lafarga
Stress-induced activation of c-Jun N-terminal kinase in sensory ganglion neurons: accumulation in nuclear domains enriched in splicing factors and distribution in perichromatin fibrils.
Experimental cell research 2000;256(1):179-91.
2000: Nuria Ajenjo; David S Aaronson; Eva Ceballos; Carlos Richard; Javier León; Piero Crespo
Myeloid leukemia cell growth and differentiation are independent of mitogen-activated protein kinase ERK1/2 activation.
The Journal of biological chemistry 2000;275(10):7189-97.
2000: M Dolores Delgado; Jose P Vaqué; Imanol Arozarena; M A López-Ilasaca; C Martínez; Piero Crespo; Javier León
H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism.
Oncogene 2000;19(6):783-90.
1999: Nieves Movilla; Piero Crespo; Xose Bustelo
Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins.
Oncogene 1999;18(43):5860-9.
1998: Piero Crespo; Jaime Font de Mora; David S Aaronson; Eugenio Santos; J Silvio Gutkind
Transforming G protein-coupled receptors block insulin and ras-induced adipocytic differentiation in 3T3-L1 cells: evidence for a PKC and MAP kinase independent pathway.
Biochemical and biophysical research communications 1998;245(2):554-61.
1997: Xose Bustelo; Piero Crespo; M López-Barahona; J Silvio Gutkind; Mariano Barbacid
Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation.
Oncogene 1997;15(21):2511-20.
1997: Piero Crespo; Kornel E Schuebel; A A Ostrom; J Silvio Gutkind; Xose Bustelo
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product.
Nature 1997;385(6612):169-72.
1997: J Silvio Gutkind; Piero Crespo; N Xu; Hidemi Teramoto; OA Coso
The pathway connecting m2 receptors to the nucleus involves small GTP-binding proteins acting on divergent MAP kinase cascades.
Life sciences 1997;60(13-14):999-1006.
1996: Hidemi Teramoto; Piero Crespo; O A Coso; Tadashi Igishi; N Xu; J Silvio Gutkind
The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway.
The Journal of biological chemistry 1996;271(42):25731-4.
1996: Piero Crespo; Xose Bustelo; D S Aaronson; O A Coso; M Lopez-Barahona; Mariano Barbacid; J Silvio Gutkind
Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav.
Oncogene 1996;13(3):455-60.
1996: Arnd Kieser; T Seitz; H S Adler; P Coffer; Elisabeth Kremmer; Piero Crespo; J Silvio Gutkind; DW Henderson; J Frederic Mushinski; Walter Kolch; Mischak Harald
Protein kinase C-zeta reverts v-raf transformation of NIH-3T3 cells.
Genes & development 1996;10(12):1455-66.
1995: Piero Crespo; T G Cachero; N Xu; J Silvio Gutkind
Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition.
The Journal of biological chemistry 1995;270(42):25259-65.
1995: Piero Crespo; Mischak Harald; J Silvio Gutkind
Overexpression of mammalian protein kinase C-zeta does not affect the growth characteristics of NIH 3T3 cells.
Biochemical and biophysical research communications 1995;213(1):266-72.
1995: O A Coso; M Chiariello; J C Yu; Hidemi Teramoto; Piero Crespo; N Xu; T Miki; J Silvio Gutkind
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway.
Cell 1995;81(7):1137-46.
1994: Piero Crespo; N Xu; J L Daniotti; J Troppmair; U R Rapp; J Silvio Gutkind
Signaling through transforming G protein-coupled receptors in NIH 3T3 cells involves c-Raf activation. Evidence for a protein kinase C-independent pathway.
The Journal of biological chemistry 1994;269(33):21103-9.
1994: Piero Crespo; N Xu; William F Simonds; J Silvio Gutkind
Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.
Nature 1994;369(6479):418-20.