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Richard Cristiano

Research Profile

Chemicals & Drugs

Procedures

Living Beings

Anatomy

Tumor Cells, Cultured

Devices

Gene Transfer Techniques

Disorders

Genes & Molecular Sequences

Genes, p53

Physiology

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Publications

TOP 3
Stanley Moffatt; Sandra A Wiehle; Richard J Cristiano
A multifunctional PEI-based cationic polyplex for enhanced systemic p53-mediated gene therapy.
Stanley Moffatt; Richard J Cristiano
Uptake characteristics of NGR-coupled stealth PEI/pDNA nanoparticles loaded with PLGA-PEG-PLGA tri-block copolymer for targeted delivery to human monocyte-derived dendritic cells.
Stanley Moffatt; Richard J Cristiano
PEGylated J591 mAb loaded in PLGA-PEG-PLGA tri-block copolymer for targeted delivery: in vitro evaluation in human prostate cancer cells.

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All Publications

2006: Stanley Moffatt; Sandra A Wiehle; Richard J Cristiano
A multifunctional PEI-based cationic polyplex for enhanced systemic p53-mediated gene therapy.
Gene therapy 2006;13(21):1512-23.
2006: Stanley Moffatt; Richard J Cristiano
Uptake characteristics of NGR-coupled stealth PEI/pDNA nanoparticles loaded with PLGA-PEG-PLGA tri-block copolymer for targeted delivery to human monocyte-derived dendritic cells.
International journal of pharmaceutics 2006;321(1-2):143-54.
2006: Stanley Moffatt; Richard J Cristiano
PEGylated J591 mAb loaded in PLGA-PEG-PLGA tri-block copolymer for targeted delivery: in vitro evaluation in human prostate cancer cells.
International journal of pharmaceutics 2006;317(1):10-3.
2006: Stanley Moffatt; C Papasakelariou; Sandra A Wiehle; Richard J Cristiano
Successful in vivo tumor targeting of prostate-specific membrane antigen with a highly efficient J591/PEI/DNA molecular conjugate.
Gene therapy 2006;13(9):761-72.
2005: Stanley Moffatt; Sandra A Wiehle; Richard J Cristiano
Tumor-specific gene delivery mediated by a novel peptide-polyethylenimine-DNA polyplex targeting aminopeptidase N/CD13.
Human gene therapy 2005;16(1):57-67.
2003: Paul Sweeney; Takashi Karashima; Hisashi Ishikura; Sandra A Wiehle; Motoyuki Yamashita; William F Benedict; Richard J Cristiano; Colin P N Dinney
Efficient therapeutic gene delivery after systemic administration of a novel polyethylenimine/DNA vector in an orthotopic bladder cancer model.
Cancer research 2003;63(14):4017-20.
2002: Richard J Cristiano
Protein/DNA polyplexes for gene therapy.
Surgical oncology clinics of North America 2002;11(3):697-716, viii.
2002: Ho-Young Lee; Kyung-Hee Chun; Bingrong Liu; Sandra A Wiehle; Richard J Cristiano; Waun Ki Hong; Pinchas Cohen; Jonathan M Kurie
Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer.
Cancer research 2002;62(12):3530-7.
2001: Motoyoshi Tanaka; GC Fraizer; J De La Cerda; Richard J Cristiano; Monica Liebert; H Barton Grossman
Connexin 26 enhances the bystander effect in HSVtk/GCV gene therapy for human bladder cancer by adenovirus/PLL/DNA gene delivery.
Gene therapy 2001;8(2):139-48.
2000: N Sueoka; Ho-Young Lee; Sandra A Wiehle; Richard J Cristiano; Bingliang Fang; Lin Ji; Jack A Roth; Waun Ki Hong; Pinchas Cohen; Jonathan M Kurie
Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells.
Oncogene 2000;19(38):4432-6.
2000: Nancy Yen; Constantin G Ioannides; Kai Xu; Stephen G Swisher; DD Lawrence; Bonnie L Kemp; Adel K El-Naggar; Richard J Cristiano; Bingliang Fang; Bonnie S Glisson; Waun Ki Hong; Fadlo R Khuri; Jonathan M Kurie; J J Lee; J S Lee; James A Merritt; Tapas Mukhopadhyay; Jonathan C Nesbitt; Dao Nguyen; Roman Perez-Soler; Katherine M W Pisters; Joe B Putnam; DS Schrump; Dong M Shin; Garrett L Walsh; Jack A Roth
Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53).
Cancer gene therapy 2000;7(4):530-6.
2000: M Kataoka; Sandra A Wiehle; FR Spitz; Guido Schumacher; Jack A Roth; Richard J Cristiano
Down-regulation of bcl-2 is associated with p16INK4-mediated apoptosis in non-small cell lung cancer cells.
Oncogene 2000;19(12):1589-95.
2000: A Scott Pearson; FR Spitz; Stephen G Swisher; M Kataoka; Mona Sarkiss; R E Meyn; Timothy J McDonnell; Richard J Cristiano; Jack A Roth
Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):887-90.
1999: DM Beaupre; Moshe Talpaz; Frank C Marini; Richard J Cristiano; Jack A Roth; Zeev Estrov; Maher Albitar; M H Freedman; Razelle Kurzrock
Autocrine interleukin-1beta production in leukemia: evidence for the involvement of mutated RAS.
Cancer research 1999;59(12):2971-80.
1998: Richard J Cristiano
Targeted, non-viral gene delivery for cancer gene therapy.
Frontiers in bioscience : a journal and virtual library 1998;3():D1161-70.
1998: M Kataoka; Guido Schumacher; Richard J Cristiano; E Neely Atkinson; Jack A Roth; Tapas Mukhopadhyay
An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo.
Cancer research 1998;58(21):4761-5.
1998: B Xu; Sandra A Wiehle; Jack A Roth; Richard J Cristiano
The contribution of poly-L-lysine, epidermal growth factor and streptavidin to EGF/PLL/DNA polyplex formation.
Gene therapy 1998;5(9):1235-43.
1998: Richard J Cristiano
Viral and non-viral vectors for cancer gene therapy.
Anticancer research 1998;18(5A):3241-5.
1998: Richard J Cristiano; B Xu; Dao Nguyen; Guido Schumacher; M Kataoka; FR Spitz; Jack A Roth
Viral and nonviral gene delivery vectors for cancer gene therapy.
Cancer detection and prevention 1998;22(5):445-54.
1997: Dao Nguyen; Sandra A Wiehle; Patricia E Koch; Cynthia D Branch; Nancy Yen; Jack A Roth; Richard J Cristiano
Delivery of the p53 tumor suppressor gene into lung cancer cells by an adenovirus/DNA complex.
Cancer gene therapy 1997;4(3):191-8.
1997: Dao Nguyen; Sandra A Wiehle; Jack A Roth; Richard J Cristiano
Gene delivery into malignant cells in vivo by a conjugated adenovirus/DNA complex.
Cancer gene therapy 1997;4(3):183-90.
1997: Jack A Roth; Richard J Cristiano
Gene therapy for cancer: what have we done and where are we going?
Journal of the National Cancer Institute 1997;89(1):21-39.
1996: FR Spitz; Dao Nguyen; John M Skibber; J Cusack; Jack A Roth; Richard J Cristiano
In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal cancer.
Anticancer research 1996;16(6B):3415-22.
1996: Dao Nguyen; FR Spitz; Nancy Yen; Richard J Cristiano; Jack A Roth
Gene therapy for lung cancer: enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer.
The Journal of thoracic and cardiovascular surgery 1996;112(5):1372-6; discussion 1376-7.
1996: FR Spitz; Dao Nguyen; John M Skibber; R E Meyn; Richard J Cristiano; Jack A Roth
Adenoviral-mediated wild-type p53 gene expression sensitizes colorectal cancer cells to ionizing radiation.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(10):1665-71.
1996: Ramon Alemany; S Ruan; M Kataoka; Patricia E Koch; T Mukhopadhyay; Richard J Cristiano; Jack A Roth; W W Zhang
Growth inhibitory effect of anti-K-ras adenovirus on lung cancer cells.
Cancer gene therapy 1996;3(5):296-301.
1996: J C Cusack; FR Spitz; Dao Nguyen; W W Zhang; Richard J Cristiano; Jack A Roth
High levels of gene transduction in human lung tumors following intralesional injection of recombinant adenovirus.
Cancer gene therapy 1996;3(4):245-9.
1996: Richard J Cristiano; D T Curiel
Strategies to accomplish gene delivery via the receptor-mediated endocytosis pathway.
Cancer gene therapy 1996;3(1):49-57.
1996: Richard J Cristiano; Jack A Roth
Epidermal growth factor mediated DNA delivery into lung cancer cells via the epidermal growth factor receptor.
Cancer gene therapy 1996;3(1):4-10.
1995: Richard J Cristiano; J A Roth
Molecular conjugates: a targeted gene delivery vector for molecular medicine.
Journal of molecular medicine (Berlin, Germany) 1995;73(10):479-86.
1995: Z M Ding; Richard J Cristiano; Jack A Roth; B Takacs; M Tien Kuo
Malarial circumsporozoite protein is a novel gene delivery vehicle to primary hepatocyte cultures and cultured cells.
The Journal of biological chemistry 1995;270(8):3667-76.

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