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Carlo Croce

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Chemicals & Drugs

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Flavia Pichiorri; Claudia Piovan; Alberto Rocci; Charles L Shapiro; Tiffany Talabere; Stefano Volinia; Jia You; Veronica Balatti; John C Byrd; Luciano Cascione; Jessica Consiglio; Vincenzo Coppola; Luciana De Luca; Michael A Freitas; Pierluigi Gasparini; Jingwen Guan; Craig C Hofmeister; Alessandro Lagana; Guido Marcucci; Gerard Nuovo; Dario Palmieri; Carlo M Croce
In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation.
Esmerina Tili; Jean-Jacques Michaille; Carlo M Croce
MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.
Stefano Volinia; Carlo M Croce
Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer.

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All Publications

2013: Flavia Pichiorri; Claudia Piovan; Alberto Rocci; Charles L Shapiro; Tiffany Talabere; Stefano Volinia; Jia You; Veronica Balatti; John C Byrd; Luciano Cascione; Jessica Consiglio; Vincenzo Coppola; Luciana De Luca; Michael A Freitas; Pierluigi Gasparini; Jingwen Guan; Craig C Hofmeister; Alessandro Lagana; Guido Marcucci; Gerard Nuovo; Dario Palmieri; Carlo M Croce
In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation.
The Journal of experimental medicine 2013;210(5):951-68.
2013: Esmerina Tili; Jean-Jacques Michaille; Carlo M Croce
MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.
Immunological reviews 2013;253(1):167-84.
2013: Stefano Volinia; Carlo M Croce
Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(18):7413-7.
2013: Rossana Trotta; Lianbo Yu; Edward L Briercheck; Li Chen; David Ciarlariello; Stefan Costinean; Carlo M Croce; Srirama Josyula; Charlene Mao; Kathleen K McConnell; Anjali Mishra; Bethany L Mundy-Bosse; Michael A Caligiuri
Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
Blood 2013;121(16):3126-34.
2013: shih-shih chen; Franak Batliwalla; Carlo M Croce; Nichol E Holodick; Thomas L Rothstein; Xiao-Jie Yan; Sophia Yancopoulos; Nicholas Chiorazzi
Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(16):E1500-7.
2013: Gianpiero Di Leva; Marco Galasso; Michela Garofalo; Pierluigi Gasparini; Marilena V Iorio; Meng Li; Guido Marcucci; Kenneth P Nephew; Apollinaire Ngankeu; Gerard Nuovo; Danilo Perrotti; Claudia Piovan; Kimerly A Powell; Santhanam Ramasamy; Cristian Taccioli; Hansjuerg Alder; Laura Anderlucci; Brad Bolon; Anna Bratasz; Daniel Briskin; Douglas G Cheung; Carlo M Croce
Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status.
PLoS genetics 2013;9(3):e1003311.
2013: V Balatti; A Bottoni; L Cascione; M J Keating; Thomas Kipps; S Lerner; Alexey Palamarchuk; yuri pekarsky; Laura Rassenti; L Rizzotto; Hansjuerg Alder; Carlo M Croce
Trisomy 12 CLLs progress through NOTCH1 mutations.
Leukemia 2013;27(3):740-3.
2013: Gianpiero Di Leva; Carlo M Croce
miRNA profiling of cancer.
Current opinion in genetics & development 2013;23(1):3-11.
2013: Muller Fabbri; Roberta Galli; Alessio Paone; Federica Calore; Carlo M Croce
A new role for microRNAs, as ligands of Toll-like receptors.
RNA biology 2013;10(2):169-74.
2013: Eugenio Gaudio; Thomas J Kipps; Gregory B Lesinski; Chenglong Li; Francesca Lovat; Apollinaire Ngankeu; Francesco Paduano; Yong Peng; Laura Rassenti; Mohammed A Shuaib; Hui-Lung Sun; Francesco Trapasso; nicola zanesi; Rami I Aqeilan; Alexey Efanov; Muller Fabbri; Pierluigi Gasparini; Carlo M Croce
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.
Blood 2013;121(2):351-9.
2013: Robert S Hudson; Chang-Gong Liu; Robyn L Prueitt; Aaron J Schetter; Robert M Stephens; Katrien Van Roosbroeck; Natalia Volfovsky; Stefano Volinia; Ming Yi; George A Calin; Carlo M Croce; Dominic Esposito; Sharon Anneve Glynn
Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer.
Molecular cancer 2013;12():13.
2013: Luciano Cascione; Carlo M Croce; Alfredo Ferro; Pierluigi Gasparini; Gang He; Francesca Lovat; Alfredo Pulvirenti; Charles L Shapiro; Andrea Vecchione; Hansjuerg Alder; Stefania Carasi; Kay Huebner
Integrated microRNA and mRNA signatures associated with survival in triple negative breast cancer.
PloS one 2013;8(2):e55910.
2012: Mohammad Q Hassan; Mohammad Jafferji; Zhaoyong Li; Yukiko Maeda; Gary S Stein; Janet L Stein; Hanna Taipaleenmaki; Andre J van Wijnen; Weibing Zhang; Carlo M Croce; Jonathan A R Gordon; Jane B Lian
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells.
The Journal of biological chemistry 2012;287(50):42084-92.
2012: Sukhinder K Sandhu; Ramasamy Santhanam; Stefano Volinia; Stefan Costinean; Marco Galasso; Ramiro Garzon; Guido Marcucci; Reid Neinast; Mark R Parthun; Danilo Perrotti; Carlo M Croce
miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(49):20047-52.
2012: Alessandro Laganà; Valentina Macca; Giovanni Nigita; Alessio Paone; Alfredo Pulvirenti; Francesco Russo; Dennis E Shasha; Dario Veneziano; Stefania Carasi; Luciano Cascione; Alfredo Ferro; Pierluigi Gasparini; Rosalba Giugno; Carlo M Croce
miR-EdiTar: a database of predicted A-to-I edited miRNA target sites.
Bioinformatics (Oxford, England) 2012;28(23):3166-8.
2012: Francesco Paduano; Camillo Palmieri; Nicola Perrotti; Cinzia Raso; Marina Sala; Giuseppe Scala; Giuseppe Viglietto; Valter Agosti; Stefano Alcaro; Anna Artese; Anna Bilotta; Pietro Campiglia; Alfonso Carotenuto; Carlo M Croce; Giovanni Cuda; Alfredo Fusco; Marco Gaspari; Eugenio Gaudio; Isabel Gomez-Monterrey; Enrico Iaccino; Rodolfo Iuliano; Graziella Mangone; Domenico Narciso; Ettore Novellino; Francesco Ortuso; Francesco Trapasso
Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity.
ACS chemical biology 2012;7(10):1666-76.
2012: Giulia Romano; Ciro Zanca; Gianpiero Di Leva; Michela Garofalo; Mario Acunzo; Brad Bolon; Luciano Cascione; Gerolama Condorelli; Carlo M Croce
MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(41):16570-5.
2012: Esmerina Tili; Stefano Volinia; Thomas J Kipps; Zhenghua Luo; Jean-Jacques Michaille; Laura Rassenti; Carlo M Croce
The down-regulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state.
Blood 2012;120(13):2631-8.
2012: Hansjuerg Alder; Hongping Chen; Carlo M Croce; Paolo Fadda; John L Farber; Kay Huebner; Yubao Jiang; Hatice G Ozer; Karl J. Smalley; Cristian Taccioli; Louise Y Y Fong
Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer.
Carcinogenesis 2012;33(9):1736-44.
2012: Elisa Callegari; Fabio Corrà; Carlo M Croce; Lucilla D'Abundo; Bahaeldin K Elamin; Manuela Ferracin; Francesca Fornari; Luciano Giacomelli; Ferdinando Giannone; Laura Gramantieri; Laura Lupini; Maddalena Milazzo; Elena Miotto; Giuseppe Altavilla; Cristian Bassi; Luigi Bolondi; Silvia Sabbioni; Barbara Zagatti; Massimo Negrini
Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model.
Hepatology (Baltimore, Md.) 2012;56(3):1025-33.
2012: Parvathi Ranganathan; Ramasamy Santhanam; Sharon Shacham; Alison Walker; Xueyan Yu; William Blum; Michael Caligiuri; Carlo M Croce; Michael Kauffman; Rebecca B Klisovic; Guido Marcucci; Caroline Na; Ramiro Garzon
Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia.
Blood 2012;120(9):1765-73.
2012: Kristen M Smith; Jessica L Williams; Arianna Bottoni; Stefan Costinean; Carlo M Croce; Mireia Guerau-de-Arellano; Amy E Lovett-Racke; Gina Mavrikis Cox; Michael K Racke; Abhay R Satoskar; Caroline C Whitacre
miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(4):1567-76.
2012: Crystina L Kriss; Adam W Mailloux; Javier A Pinilla-Ibarz; John Joseph Powers; Eduardo M Sotomayor; Chih-Hang Anthony Tang; nicola zanesi; Carlo M Croce; Juan R Del Valle; Pearlie K Epling-Burnette; Chang Won Kang; Chih-Chi Andrew Hu
Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice.
Blood 2012;120(5):1027-38.
2012: Claudia Piovan; Ilaria Plantamura; Marianna Sasso; Cristian Taccioli; Elda Tagliabue; Monica Tortoreto; Tiziana Triulzi; Gianpiero Di Leva; Marilena V Iorio; Gerard Nuovo; Dario Palmieri; Luca Braccioli; Patrizia Casalini; Carlo M Croce
Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer.
Molecular oncology 2012;6(4):458-72.
2012: Ewy Mathé; Matthew Moake; Giang H Nguyen; Carlo M Croce; Naotake Funamizu; Peijun He; S Perwez Hussain
Inflammation regulates microRNA expression in cooperation with p53 and nitric oxide.
International journal of cancer. Journal international du cancer 2012;131(3):760-5.
2012: Muller Fabbri; Paolo Fadda; Roberta Galli; Eugenio Gaudio; Francesca Lovat; Charlene Mao; Patrick Nana-Sinkam; Gerard J Nuovo; Gulcin H Ozer; Alessio Paone; Danilo Perrotti; Ramasamy Santhanam; Dorothee Wernicke; nicola zanesi; Hansjuerg Alder; Michael A Caligiuri; Federica Calore; Melissa Crawford; Carlo M Croce
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(31):E2110-6.
2012: Francesca Fornari; Luigi Bolondi; Elisa Callegari; Giovanni Capranico; Matteo Cescon; Pasquale Chieco; Carlo M Croce; Vilma Mantovani; Elena Marasco; Jessica Marinello; Maddalena Milazzo; Massimo Negrini; Matteo Ravaioli; Silvia Sabbioni; Laura Gramantieri
In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.
The Journal of pathology 2012;227(3):275-85.
2012: Hongyan Wang; Zhiliang Xie; John C Byrd; Ping Chen; Michael Chiu; Ming Chiu; Carlo M Croce; Ramiro Garzon; Shujun Liu; Zhongfa Liu; Guido Marcucci; Natarajan Muthusamy; Kenneth K Chan
Synthetic microRNA cassette dosing: pharmacokinetics, tissue distribution and bioactivity.
Molecular pharmaceutics 2012;9(6):1638-44.
2012: Marilena V Iorio; Carlo M Croce
microRNA involvement in human cancer.
Carcinogenesis 2012;33(6):1126-33.
2012: Raffaela Pero; Teresa Valentino; Simon D Wagner; Tiziana Angrisano; Claudio Arra; Lorenzo Chiariotti; Carlo M Croce; Luigi Del Vecchio; Antonella Federico; Renato Franco; Alfredo Fusco; Simona Keller; Andres J Klein-Szanto; Francesca Lembo; Donatella Montanaro; Dario Palmieri; Vasiliki Papadopoulou; Monica Fedele
POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.
The Journal of biological chemistry 2012;287(22):18308-17.
2012: Parvathi Ranganathan; Sukhinder Sandhu; Ramasamy Santhanam; Arwa Shana'ah; Nicole Stauffer; Patricia A Taylor; Bruce R Blazar; Oliver Broom; John C Byrd; Michael Caligiuri; Luciano Cascione; Stefan Costinean; Carlo M Croce; Steven M Devine; Gregg A Hadley; Mehdi Hamadani; Gang He; Catherine E A Heaphy; Sakari Kauppinen; Alessandro Lagana; Charlene Mao; Guido Marcucci; Caroline Na; Gerard J Nuovo; Susanna Obad; Danilo Perrotti; Ramiro Garzon
Regulation of acute graft-versus-host disease by microRNA-155.
Blood 2012;119(20):4786-97.
2012: Marilena V Iorio; Carlo M Croce
Causes and consequences of microRNA dysregulation.
Cancer journal (Sudbury, Mass.) 2012;18(3):215-22.
2012: Gianpiero Di Leva; Daniel Briskin; Carlo M Croce
MicroRNA in cancer: new hopes for antineoplastic chemotherapy.
Upsala journal of medical sciences 2012;117(2):202-16.
2012: Rossana Trotta; Lianbo Yu; Jon Butchar; Li Chen; David Ciarlariello; Stefan Costinean; Carlo M Croce; Srirama Josyula; Charlene Mao; Susheela Tridandapani; Michael A Caligiuri
miR-155 regulates IFN-γ production in natural killer cells.
Blood 2012;119(15):3478-85.
2012: Sung-Suk Suh; Ji Young Yoo; Hansjuerg Alder; Rami I Aqeilan; Arianna Bakàcs; Young-Jun Jeon; Balveen Kaur; Seokho Kim; Taewan Kim; Tae Jin Lee; Gerard J Nuovo; Flavia Pichiorri; Carlo M Croce
MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(14):5316-21.
2012: Kevin B Jones; Kimberly LeBlanc; Jane B Lian; Francesca Lovat; Gerard J Nuovo; Jeff Palatini; R Lor Randall; Zaidoun Salah; Gary S Stein; Stefano Volinia; Carlo M Croce; Sara Del Mare; Marco Galasso; Eugenio Gaudio; Rami I Aqeilan
miRNA signatures associate with pathogenesis and progression of osteosarcoma.
Cancer research 2012;72(7):1865-77.
2012: Robert S Hudson; Arthur A Hurwitz; Dong H Lee; Michael J Naslund; Robert M Stephens; Stephanie K Watkins; Harris G Yfantis; Ming Yi; James F Borin; Carlo M Croce; Tiffany H Dorsey; Dominic Esposito; Richard B Alexander; Sharon Anneve Glynn
MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer.
Nucleic acids research 2012;40(8):3689-703.
2012: Marilena V Iorio; Carlo M Croce
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review.
EMBO molecular medicine 2012;4(3):143-59.
2012: Wan Zhang; Jan A Burger; Gang Chen; Carlo M Croce; Celia Garcia-Prieto; Michael J Keating; Jinyun Liu; Weiqin Lu; Helene Pelicano; William Plunkett; Dunyaporn Trachootham; Peng Huang
Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia.
Nature cell biology 2012;14(3):276-86.
2012: Stefano Volinia; Timothy F Wise; Marco Galasso; Kay Huebner; Jeff Palatini; Maria Elena Sana; Carlo M Croce
Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(8):3024-9.
2012: C Quintavalle; Giovanni Romano; C Zanca; Carlo M Croce; M del Basso De Caro; M Garofalo; M Iaboni; Mariarosaria Incoronato; J C Martinez-Montero; G Nuovo; Gianluigi Condorelli
miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ.
Oncogene 2012;31(7):858-68.
2012: Alexey Palamarchuk; Laura Rassenti; Benjamin Rodrigues; Linan Wang; Pearlly S Yan; nicola zanesi; Hansjuerg Alder; Veronica Balatti; Arianna Bottoni; Carlo M Croce; Michael Freitas; Thomas J Kipps; Mark Murphy; Natalya Nazaryan; yuri pekarsky
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):2555-60.
2012: M Acunzo; A Bottoni; M Chiariello; G Condorelli; M Garofalo; P Gasparini; F Lovat; D Palmieri; G Romano; Angelo Veronese; Rosa Visone; Carlo M Croce
miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222.
Oncogene 2012;31(5):634-42.
2012: Rosa Visone; Angelo Veronese; Veronica Balatti; Carlo M Croce
MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia.
Oncotarget 2012;3(2):195-202.
2012: Veronica Balatti; Arianna Bottoni; Hansjuerg Alder; Thomas J Kipps; Alexey Palamarchuk; yuri pekarsky; Laura Rassenti; Carlo M Croce
NOTCH1 mutations in CLL associated with trisomy 12.
Blood 2012;119(2):329-31.
2012: nicola zanesi; Veronica Balatti; Arianna Bottoni; Carlo M Croce; yuri pekarsky
Novel insights in molecular mechanisms of CLL.
Current pharmaceutical design 2012;18(23):3363-72.
2012: M Garofalo; C Quintavalle; G Romano; Carlo M Croce; G Condorelli
miR221/222 in cancer: their role in tumor progression and response to therapy.
Current molecular medicine 2012;12(1):27-33.
2011: Francesca Lovat; Nicola Valeri; Carlo M Croce
MicroRNAs in the pathogenesis of cancer.
Seminars in oncology 2011;38(6):724-33.
2011: Ramiro Garzon; Carlo M Croce
MicroRNAs and cancer: introduction.
Seminars in oncology 2011;38(6):721-3.
2011: S Patrick Nana-Sinkam; Carlo M Croce
Non-coding RNAs in cancer initiation and progression and as novel biomarkers.
Molecular oncology 2011;5(6):483-91.
2011: Tasneem Motiwala; Satavisha Roy; nicola zanesi; Yiming Zhong; John C Byrd; Allyn M Checovich; Carlo M Croce; Jharna Datta; John Patrick Hagan; Nyla A Heerema; David Jarjoura; Amy J Johnson; Mohamed Kaou; Huban Kutay; David M Lucas; Xiaokui Mo; Samson T Jacob
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia.
Blood 2011;118(23):6132-40.
2011: Chiara Braconi; Stefan Costinean; Carlo M Croce; N Huang; T Kogure; E Miotto; Massimo Negrini; G Nuovo; N Valeri; tushar patel
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer.
Oncogene 2011;30(47):4750-6.
2011: Violaine Havelange; Catherine C E Heaphy; Guido Marcucci; Nicole Stauffer; Stefano Volinia; Michael Andreeff; Carlo M Croce; Ramiro Garzon
Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profiling.
Cancer 2011;117(20):4696-706.
2011: Cristina Quintavalle; Carlo M Croce; Michela Garofalo; Gerolama Condorelli
"ApoptomiRs" in vascular cells: their role in physiological and pathological angiogenesis.
Vascular pharmacology 2011;55(4):87-91.
2011: Matteo Fassan; Jeff Palatini; Paola Parente; Marco Pizzi; Ermanno Ancona; Raffaele Baffa; Giorgio Battaglia; Carlo M Croce; Marina de Bernard; Stefano Volinia; Giovanni Zaninotto; Massimo Rugge
MicroRNA expression profiling in human Barrett's carcinogenesis.
International journal of cancer. Journal international du cancer 2011;129(7):1661-70.
2011: V Grignol; J E Kacher; V I Karpa; A Lehman; Gregory B Lesinski; C M Magro; G Nuovo; S Volinia; M J Walker; Jason M Zimmerer; Doreen M Agnese; J Clark; Carlo M Croce; E T Fairchild; W E Carson
miR-21 and miR-155 are associated with mitotic activity and lesion depth of borderline melanocytic lesions.
British journal of cancer 2011;105(7):1023-9.
2011: Rosa Visone; Stefano Volinia; Mario Acunzo; Veronica Balatti; Thomas J Kipps; Dennis K Pearl; Laura Rassenti; Cristian Taccioli; Angelo Veronese; Carlo M Croce
miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia.
Blood 2011;118(11):3072-9.
2011: Violaine Havelange; Thomas Kipps; Tatsuya Nakamura; Alexey Palamarchuk; yuri pekarsky; Laura Rassenti; Hansjuerg Alder; Carlo M Croce
IRF4 mutations in chronic lymphocytic leukemia.
Blood 2011;118(10):2827-9.
2011: Manuela Ferracin; Roberta Gafà; Giovanni Lanza; Maria Lunardi; Iva Maestri; Eros Magri; Gardenia Munerato; italo nenci; Massimo Pedriali; Giulia Querzoli; Patrizia Querzoli; Linda Ulazzi; Angelo Veronese; Barbara Zagatti; Carlo M Croce; Massimo Negrini
MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin.
The Journal of pathology 2011;225(1):43-53.
2011: Carlo M Croce
miRNAs in the spotlight: Understanding cancer gene dependency.
Nature medicine 2011;17(8):935-6.
2011: Shao-Gui Wan; Hongping Chen; Carlo M Croce; John L Farber; Kun Huang; Yubao Jiang; Xiu-Ping Liu; Karl J. Smalley; Cristian Taccioli; Louise Y Y Fong
Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression.
International journal of cancer. Journal international du cancer 2011;129(2):331-45.
2011: Dario Palmieri; I Postiglione; T Valentino; Roberto Pacelli; Carlo M Croce; Daniela D'Angelo; Ivana De Martino; Monica Fedele; Alfredo Fusco
HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents.
Oncogene 2011;30(27):3024-35.
2011: Gabriella Sozzi; Ugo Pastorino; Carlo M Croce
MicroRNAs and lung cancer: from markers to targets.
Cell cycle (Georgetown, Tex.) 2011;10(13):2045-6.
2011: Massimo Negrini; Silvia Sabbioni; Laura Gramantieri; Carlo M Croce
microRNA involvement in hepatocellular carcinoma.
Anti-cancer agents in medicinal chemistry 2011;11(6):500-21.
2011: Muller Fabbri; Carlo M Croce
Role of microRNAs in lymphoid biology and disease.
Current opinion in hematology 2011;18(4):266-72.
2011: Ying Zhang; Carlo M Croce; Jane B Lian; Janet L Stein; Andre J van Wijnen; Rong-Lin Xie; Gary S Stein
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(24):9863-8.
2011: Kira Orlovsky; Alexander Kalinkovich; Tanya Rozovskaia; Elias Shezen; Tomer Itkin; Hansjuerg Alder; Hatice Gulcin Ozer; Letizia Carramusa; Abraham Avigdor; Stefano Volinia; Arthur Buchberg; Alexander Mazo; Orit Kollet; Corey Largman; Carlo M Croce; Tatsuya Nakamura; Tsvee Lapidot; Eli Canaani
Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(19):7956-61.
2011: Taewan Kim; Angelo Veronese; Flavia Pichiorri; Tae Jin Lee; Young-Jun Jeon; Stefano Volinia; Pascal Pineau; Agnès Marchio; Jeff Palatini; Sung-Suk Suh; Hansjuerg Alder; Chang-Gong Liu; Anne Dejean; Carlo M Croce
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.
The Journal of experimental medicine 2011;208(5):875-83.
2011: S Patrick Nana-Sinkam; Carlo M Croce
MicroRNAs as therapeutic targets in cancer.
Translational research : the journal of laboratory and clinical medicine 2011;157(4):216-25.
2011: Lubomir Sokol; Gisela Caceres; Stefano Volinia; Hans Alder; Gerard J Nuovo; Chang-Gong Liu; Kathy McGraw; Justine A Clark; Celia A Sigua; Dung-Tsa Chen; Lynn Moscinski; Carlo M Croce; Alan F List
Identification of a risk dependent microRNA expression signature in myelodysplastic syndromes.
British journal of haematology 2011;153(1):24-32.
2011: Louise Y Y Fong; Yubao Jiang; Maysoon L Rawahneh; Karl J. Smalley; Carlo M Croce; John L Farber; Kay Huebner
Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis.
Carcinogenesis 2011;32(4):554-60.
2011: Esmerina Tili; Jean-Jacques Michaille; Dorothee Wernicke; Hansjuerg Alder; Stefan Costinean; Stefano Volinia; Carlo M Croce
Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):4908-13.
2011: Angelo Veronese; Rosa Visone; Jessica Consiglio; Mario Acunzo; Laura Lupini; Taewan Kim; Manuela Ferracin; Francesca Lovat; Elena Miotto; Veronica Balatti; Lucilla D'Abundo; Laura Gramantieri; Luigi Bolondi; yuri pekarsky; Danilo Perrotti; Massimo Negrini; Carlo M Croce
Mutated beta-catenin evades a microRNA-dependent regulatory loop.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):4840-5.
2011: Sonia Melo; Alberto Villanueva; Catia Moutinho; Veronica Davalos; Riccardo Spizzo; Cristina Ivan; Simona Rossi; Fernando Setien; Oriol Casanovas; Laia Simo-Riudalbas; Javier Carmona; Jordi Carrere; August Vidal; Alvaro Aytes; Sara Puertas; Santiago Ropero; Raghu Kalluri; Carlo M Croce; George A Calin; Manel Esteller
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(11):4394-9.
2011: Mattia Boeri; Carla Verri; Davide Conte; Luca Roz; Piergiorgio Modena; Federica Facchinetti; Elisa Calabrò; Carlo M Croce; Ugo Pastorino; Gabriella Sozzi
MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(9):3713-8.
2011: Jin Sun; James Liu; Xueliang Pan; Donald Quimby; nicola zanesi; Teresa Druck; Gerd P Pfeifer; Carlo M Croce; Louise Y Fong; Kay Huebner
Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.
Carcinogenesis 2011;32(3):351-8.
2011: Aruna Basu; Carlo M Croce; Amer Khiyami; Patrick Leahy; Hansjuerg Alder; Subrata Haldar
MicroRNA-375 and MicroRNA-221: Potential Noncoding RNAs Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer.
Genes & cancer 2011;2(2):108-19.
2011: Monica Fedele; Rosa Visone; Ivana De Martino; Dario Palmieri; Teresa Valentino; Francesco Esposito; Andres Klein-Szanto; Claudio Arra; Andrea Ciarmiello; Carlo M Croce; Alfredo Fusco
Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice.
European journal of cancer (Oxford, England : 1990) 2011;47(3):470-8.
2011: Chiara Braconi; Nicola Valeri; Takayuki Kogure; Pierluigi Gasparini; Nianyuan Huang; Gerard J Nuovo; Luigi Terracciano; Carlo M Croce; Tushar Patel
Expression and functional role of a transcribed noncoding RNA with an ultraconserved element in hepatocellular carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(2):786-91.
2011: Muller Fabbri; Arianna Bottoni; Masayoshi Shimizu; Riccardo Spizzo; Milena S Nicoloso; Simona Rossi; Elisa Barbarotto; Amelia Cimmino; Brett Adair; Sylwia E Wojcik; Nicola Valeri; Federica Calore; Deepa Sampath; Francesca Fanini; Ivan Vannini; Gerardo Musuraca; Marie Dell'Aquila; Hansjuerg Alder; Ramana V Davuluri; Laura Rassenti; Massimo Negrini; Tatsuya Nakamura; Dino Amadori; Neil E Kay; Kanti R Rai; Michael J Keating; Thomas J Kipps; George A Calin; Carlo M Croce
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia.
JAMA : the journal of the American Medical Association 2011;305(1):59-67.
2011: Sukhinder K Sandhu; Carlo M Croce; Ramiro Garzon
Micro-RNA Expression and Function in Lymphomas.
Advances in hematology 2011;2011():347137.
2011: Michela Garofalo; Carlo M Croce
microRNAs: Master regulators as potential therapeutics in cancer.
Annual review of pharmacology and toxicology 2011;51():25-43.
2010: Esmerina Tili; Jean-Jacques Michaille; Hansjuerg Alder; Stefano Volinia; Dominique Delmas; Norbert Latruffe; Carlo M Croce
Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells.
Biochemical pharmacology 2010;80(12):2057-65.
2010: Nicola Valeri; Pierluigi Gasparini; Chiara Braconi; Alessio Paone; Francesca Lovat; Muller Fabbri; Khlea M Sumani; Hansjuerg Alder; Dino Amadori; Tushar Patel; Gerard J Nuovo; Richard Fishel; Carlo M Croce
MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2).
Proceedings of the National Academy of Sciences of the United States of America 2010;107(49):21098-103.
2010: amaia lujambio; A Portela; J Liz; S A Melo; S Rossi; R Spizzo; Carlo M Croce; George A Calin; Manel Esteller
CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer.
Oncogene 2010;29(48):6390-401.
2010: S Patrick Nana-Sinkam; Carlo M Croce
MicroRNA in chronic lymphocytic leukemia: transitioning from laboratory-based investigation to clinical application.
Cancer genetics and cytogenetics 2010;203(2):127-33.
2010: S Patrick Nana-Sinkam; Carlo M Croce
MicroRNA dysregulation in cancer: opportunities for the development of microRNA-based drugs.
IDrugs : the investigational drugs journal 2010;13(12):843-6.
2010: yuri pekarsky; nicola zanesi; Carlo M Croce
Molecular basis of CLL.
Seminars in cancer biology 2010;20(6):370-6.
2010: Rodolfo Iuliano; Dario Palmieri; Huiling He; Angela Iervolino; Eleonora Borbone; pierlorenzo pallante; Alessandra Cianflone; Rebecca Nagy; Hansjuerg Alder; George A Calin; Francesco Trapasso; Carla Giordano; Carlo M Croce; ALBERT DE LA CHAPELLE; Alfredo Fusco
Role of PTPRJ genotype in papillary thyroid carcinoma risk.
Endocrine-related cancer 2010;17(4):1001-6.
2010: Kenneth K Chan; Zhongfa Liu; Zhiliang Xie; Ming Chiu; Hongyan Wang; Ping Chen; Sarah Dunkerson; Michael Chiu; Shujun Liu; Georgia Triantafillou; Ramiro Garzon; Carlo M Croce; John C Byrd; Natarajan Muthusamy; Guido Marcucci
A novel ultrasensitive hybridization-based ELISA method for 2-methoxyphosphorothiolate microRNAs and its in vitro and in vivo application.
The AAPS journal 2010;12(4):556-68.
2010: C Quintavalle; Mariarosaria Incoronato; L Puca; M Acunzo; C Zanca; G Romano; M Garofalo; M Iaboni; Carlo M Croce; Gianluigi Condorelli
c-FLIPL enhances anti-apoptotic Akt functions by modulation of Gsk3β activity.
Cell death and differentiation 2010;17(12):1908-16.
2010: Stefano Cairo; Yipeng Wang; Aurélien de Reyniès; Karine Duroure; Jennifer Dahan; Marie-José Redon; Monique Fabre; Michael McClelland; Xin W Wang; Carlo M Croce; Marie Annick Buendia
Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(47):20471-6.
2010: Mohammad Q Hassan; Jonathan A R Gordon; Marcio M Beloti; Carlo M Croce; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19879-84.
2010: Pedro de Souza Rocha Simonini; Achim Breiling; Nibedita Gupta; Mahdi Malekpour; Mahmoud Youns; Ramesh Omranipour; Fatemeh Malekpour; Stefano Volinia; Carlo M Croce; Hossein Najmabadi; Sven Diederichs; Ozgür Sahin; Doris Mayer; Frank Lyko; Jörg D Hoheisel; Yasser Riazalhosseini
Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells.
Cancer research 2010;70(22):9175-84.
2010: Esmerina Tili; Jean-Jacques Michaille; Chang-gong liu; Hansjuerg Alder; Cristian Taccioli; Stefano Volinia; George A Calin; Carlo M Croce
GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGF{beta} effectors, Drosha and microRNAs with opposite oncogenic potentials.
Nucleic acids research 2010;38(21):7673-88.
2010: Flavia Pichiorri; Sung-Suk Suh; Alberto Rocci; Luciana De Luca; Cristian Taccioli; Ramasamy Santhanam; Wenchao Zhou; Don M Benson; Craig Hofmainster; Hansjuerg Alder; Michela Garofalo; Gianpiero Di Leva; Stefano Volinia; Huey-Jen Lin; Danilo Perrotti; Michael Kuehl; Rami I Aqeilan; Antonio Palumbo; Carlo M Croce
Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development.
Cancer cell 2010;18(4):367-81.
2010: S Patrick Nana-Sinkam; Muller Fabbri; Carlo M Croce
MicroRNAs in cancer: personalizing diagnosis and therapy.
Annals of the New York Academy of Sciences 2010;1210():25-33.
2010: Ramiro Garzon; Guido Marcucci; Carlo M Croce
Targeting microRNAs in cancer: rationale, strategies and challenges.
Nature reviews. Drug discovery 2010;9(10):775-89.
2010: Rocio G Urdinguio; Agustin F Fernandez; Pilar Lopez-Nieva; Simona Rossi; Dori Huertas; Marta Kulis; Chang-Gong Liu; Carlo M Croce; George A Calin; Manel Esteller
Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome.
Epigenetics : official journal of the DNA Methylation Society 2010;5(7):656-63.
2010: Marilena V Iorio; Claudia Piovan; Carlo M Croce
Interplay between microRNAs and the epigenetic machinery: an intricate network.
Biochimica et biophysica acta 2010;1799(10-12):694-701.
2010: Carlo M Croce
LINCing chromatin remodeling to metastasis.
Nature biotechnology 2010;28(9):931-2.
2010: Esmerina Tili; Jean-Jacques Michaille; Brett Adair; Hansjuerg Alder; Emeric Limagne; Cristian Taccioli; Manuela Ferracin; Dominique Delmas; Norbert Latruffe; Carlo M Croce
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD.
Carcinogenesis 2010;31(9):1561-6.
2010: Marco Gabbianelli; Ugo Testa; Ornella Morsilli; Elvira Pelosi; ernestina saulle; Eleonora Petrucci; Germana Castelli; Serena Giovinazzi; Gualtiero Mariani; Micol E Fiori; Giuseppina Bonanno; Adriana Massa; Carlo M Croce; Laura Fontana; Cesare Peschle
Mechanism of human Hb switching: a possible role of the kit receptor/miR 221-222 complex.
Haematologica 2010;95(8):1253-60.
2010: Erin Hertlein; Amy J Wagner; Jeffrey Jones; Thomas S Lin; Kami J Maddocks; William H Towns; Virginia M Goettl; Xiaoli Zhang; David Jarjoura; Chelsey A Raymond; Derek A West; Carlo M Croce; John C Byrd; Amy J Johnson
17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition.
Blood 2010;116(1):45-53.
2010: Urmila Santanam; nicola zanesi; Alexey Efanov; Stefan Costinean; Alexey Palamarchuk; John Patrick Hagan; Stefano Volinia; Hansjuerg Alder; Laura Rassenti; Thomas Kipps; Carlo M Croce; yuri pekarsky
Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(27):12210-5.
2010: yuri pekarsky; Carlo M Croce
Is miR-29 an oncogene or tumor suppressor in CLL?
Oncotarget 2010;1(3):224-7.
2010: Gianpiero Di Leva; Carlo M Croce
Roles of small RNAs in tumor formation.
Trends in molecular medicine 2010;16(6):257-67.
2010: David E Cohn; Muller Fabbri; Nicola Valeri; Hansjuerg Alder; Iouri Ivanov; Chang-gong liu; Carlo M Croce; Kimberly E Resnick
Comprehensive miRNA profiling of surgically staged endometrial cancer.
American journal of obstetrics and gynecology 2010;202(6):656.e1-8.
2010: QiQi Zhou; Wiley W Souba; Carlo M Croce; G Nicholas Verne
MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome.
Gut 2010;59(6):775-84.
2010: Gianpiero Di Leva; Pierluigi Gasparini; Claudia Piovan; Apollinaire Ngankeu; Michela Garofalo; Cristian Taccioli; Marilena V Iorio; Meng Li; Stefano Volinia; Hansjuerg Alder; Tatsuya Nakamura; Gerard Nuovo; Yunlong Liu; Kenneth P Nephew; Carlo M Croce
MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer.
Journal of the National Cancer Institute 2010;102(10):706-21.
2010: Alexey Palamarchuk; Alexey Efanov; Natalya Nazaryan; Urmila Santanam; Hansjuerg Alder; Laura Rassenti; Thomas Kipps; Carlo M Croce; yuri pekarsky
13q14 deletions in CLL involve cooperating tumor suppressors.
Blood 2010;115(19):3916-22.
2010: Patrick Nana-Sinkam; Carlo M Croce
MicroRNAs in diagnosis and prognosis in cancer: what does the future hold?
Pharmacogenomics 2010;11(5):667-9.
2010: A Efanov; nicola zanesi; N Nazaryan; U Santanam; Alexey Palamarchuk; Carlo M Croce; yuri pekarsky
CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation.
Leukemia 2010;24(5):970-5.
2010: Angelo Veronese; Laura Lupini; Jessica Consiglio; Rosa Visone; Manuela Ferracin; Francesca Fornari; nicola zanesi; Hansjuerg Alder; Gemma D'Elia; Laura Gramantieri; Luigi Bolondi; Roberta Gafà; Patrizia Querzoli; Adriano Angioni; Carlo M Croce; Massimo Negrini
Oncogenic role of miR-483-3p at the IGF2/483 locus.
Cancer research 2010;70(8):3140-9.
2010: Shujun Liu; Lai-Chu Wu; Jiuxia Pang; Ramasamy Santhanam; Sebastian Schwind; Yue-Zhong Wu; Christopher J Hickey; Jianhua Yu; Heiko Becker; Kati Maharry; Michael D Radmacher; Chenglong Li; Susan P Whitman; Anjali Mishra; Nicole Stauffer; Anna Eiring; Roger Briesewitz; Robert A Baiocchi; Kenneth K Chan; Peter Paschka; Michael A Caligiuri; John C Byrd; Carlo M Croce; Clara D Bloomfield; Danilo Perrotti; Ramiro Garzon; Guido Marcucci
Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia.
Cancer cell 2010;17(4):333-47.
2010: Nicola Valeri; Pierluigi Gasparini; Muller Fabbri; Chiara Braconi; Angelo Veronese; Francesca Lovat; Brett Adair; Ivan Vannini; Francesca Fanini; Arianna Bottoni; Stefan Costinean; Sukhinder K Sandhu; Gerard J Nuovo; Hansjuerg Alder; Roberta Gafà; Federica Calore; Manuela Ferracin; Giovanni Lanza; Stefano Volinia; Massimo Negrini; Michael A McIlhatton; Dino Amadori; Richard Fishel; Carlo M Croce
Modulation of mismatch repair and genomic stability by miR-155.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(15):6982-7.
2010: Milena S Nicoloso; Hao Sun; Riccardo Spizzo; Hyunsoo Kim; Priyankara Wickramasinghe; Masayoshi Shimizu; Sylwia E Wojcik; Jana Ferdin; Tanja Kunej; Lianchun Xiao; Siranoush Manoukian; Giorgio Secreto; Fernando Ravagnani; Xuemei Wang; Paolo Radice; Carlo M Croce; Ramana V Davuluri; George A Calin
Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility.
Cancer research 2010;70(7):2789-98.
2010: Anna Eiring; Jason G Harb; Paolo Neviani; Christopher Garton; Joshua J Oaks; Riccardo Spizzo; Shujun Liu; Sebastian Schwind; Ramasamy Santhanam; Christopher J Hickey; Heiko Becker; Jason C Chandler; Raul Andino; Jorge Cortes; Peter Hokland; Claudia S Huettner; Ravi Bhatia; Denis C Roy; Stephen A Liebhaber; Michael A Caligiuri; Guido Marcucci; Ramiro Garzon; Carlo M Croce; George A Calin; Danilo Perrotti
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts.
Cell 2010;140(5):652-65.
2010: Andrea Vecchione; Carlo M Croce
Apoptomirs: small molecules have gained the license to kill.
Endocrine-related cancer 2010;17(1):F37-50.
2010: Domenico D'Arca; James LeNoir; Bernadette Wildemore; Fedra Gottardo; Emma Bragantini; Dolores Shupp-Byrne; nicola zanesi; Matteo Fassan; Carlo M Croce; Leonard G Gomella; Raffaele Baffa
Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor.
Urologic oncology 2010;28(2):189-94.
2010: Tetsuya Ueda; Stefano Volinia; Hiroshi Okumura; Masayoshi Shimizu; Cristian Taccioli; Simona Rossi; Hansjuerg Alder; Chang-gong liu; Naohide Oue; Wataru Yasui; Kazuhiro Yoshida; Hiroki Sasaki; Sachiyo Nomura; Yasuyuki Seto; Michio Kaminishi; George A Calin; Carlo M Croce
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis.
The lancet oncology 2010;11(2):136-46.
2010: Sylwia E Wojcik; Simona Rossi; Masayoshi Shimizu; Milena S Nicoloso; Amelia Cimmino; Hansjuerg Alder; Vlad Herlea; Laura Rassenti; Kanti Rai; Thomas J Kipps; Michael J Keating; Carlo M Croce; George A Calin
Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer.
Carcinogenesis 2010;31(2):208-15.
2010: R Spizzo; Milena S Nicoloso; L Lupini; Y Lu; J Fogarty; S Rossi; B Zagatti; M Fabbri; A Veronese; X Liu; R Davuluri; Carlo M Croce; G Mills; M Negrini; George A Calin
miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells.
Cell death and differentiation 2010;17(2):246-54.
2010: M Garofalo; G L Condorelli; Carlo M Croce; G Condorelli
MicroRNAs as regulators of death receptors signaling.
Cell death and differentiation 2010;17(2):200-8.
2010: Edoardo Missiaglia; Irene Dalai; Stefano Barbi; Stefania Beghelli; Massimo Falconi; marco della peruta; Lorenzo Piemonti; Gabriele Capurso; Alessia Di Florio; Gianfranco Delle Fave; Paolo Pederzoli; Carlo M Croce; Aldo Scarpa
Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(2):245-55.
2010: Pascal Pineau; Stefano Volinia; Katherine McJunkin; Agnès Marchio; Carlo Battiston; Benoît Terris; Vincenzo Mazzaferro; Scott W Lowe; Carlo M Croce; Anne Dejean
miR-221 overexpression contributes to liver tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):264-9.
2010: Gonzalo Almanza; Antonio Fernandez; Stefano Volinia; Xochitl Cortez-Gonzalez; Carlo M Croce; Maurizio Zanetti
Selected microRNAs define cell fate determination of murine central memory CD8 T cells.
PloS one 2010;5(6):e11243.
2010: David M Lucas; Lapo Alinari; Derek A West; Melanie E Davis; Ryan B Edwards; Amy J Johnson; Kristie A Blum; Craig C Hofmeister; Michael A Freitas; Mark R Parthun; Dasheng Wang; Amy Lehman; Xiaoli Zhang; David Jarjoura; Samuel K Kulp; Carlo M Croce; Michael R Grever; Ching-Shih Chen; Robert A Baiocchi; John C Byrd
The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo.
PloS one 2010;5(6):e10941.
2010: Alberto Izzotti; George A Calin; Vernon E Steele; Cristina Cartiglia; Mariagrazia Longobardi; Carlo M Croce; Silvio De Flora
Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs.
Cancer prevention research (Philadelphia, Pa.) 2010;3(1):62-72.
2010: Stefano Volinia; Rosa Visone; Marco Galasso; Elda Rossi; Carlo M Croce
Identification of microRNA activity by Targets' Reverse EXpression.
Bioinformatics (Oxford, England) 2010;26(1):91-7.
2010: Gary S Stein; Janet L Stein; Andre J van Wijnen; Jane B Lian; Martin Montecino; Carlo M Croce; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan; Sayyed K Zaidi; Daniel W Young
Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer.
Advances in enzyme regulation 2010;50(1):160-7.
2009: Ramiro Garzon; Catherine E A Heaphy; Violaine Havelange; Muller Fabbri; Stefano Volinia; Twee Tsao; nicola zanesi; Steven M Kornblau; Guido Marcucci; George A Calin; Michael Andreeff; Carlo M Croce
MicroRNA 29b functions in acute myeloid leukemia.
Blood 2009;114(26):5331-41.
2009: Marilena V Iorio; Carlo M Croce
MicroRNAs in cancer: small molecules with a huge impact.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(34):5848-56.
2009: George A Calin; Carlo M Croce
Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes.
Blood 2009;114(23):4761-70.
2009: Thomas Enzler; Arnon P Kater; Weizhou Zhang; George F Widhopf; Han-Yu Chuang; Jason Lee; Esther Avery; Carlo M Croce; Michael Karin; Thomas J Kipps
Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression.
Blood 2009;114(20):4469-76.
2009: Sayyed K Zaidi; Christopher R Dowdy; Andre J van Wijnen; Jane B Lian; Azra Raza; Janet L Stein; Carlo M Croce; Gary S Stein
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network.
Cancer research 2009;69(21):8249-55.
2009: Rosa Visone; Laura Rassenti; Angelo Veronese; Cristian Taccioli; Stefan Costinean; Baltazar D Aguda; Stefano Volinia; Manuela Ferracin; Jeff Palatini; Veronica Balatti; Hansjuerg Alder; Massimo Negrini; Thomas Kipps; Carlo M Croce
Karyotype-specific microRNA signature in chronic lymphocytic leukemia.
Blood 2009;114(18):3872-9.
2009: Junfang Ji; Jiong Shi; Anuradha Budhu; Zhipeng Yu; Marshonna Forgues; Stephanie Roessler; Stefan Ambs; Yidong Chen; Paul S Meltzer; Carlo M Croce; Lun-Xiu Qin; Kwan Man; Chung-Mau Lo; Joyce Lee; Irene O L Ng; Jia Fan; Zhao-You Tang; Hui-Chuan Sun; Xin Wei Wang
MicroRNA expression, survival, and response to interferon in liver cancer.
The New England journal of medicine 2009;361(15):1437-47.
2009: Sathyamangla V Naga Prasad; Zhong-Hui Duan; Manveen K Gupta; Venkata Suresh K Surampudi; Stefano Volinia; George A Calin; Chang-gong liu; Ashwin Kotwal; Christine S Moravec; Randall C Starling; Dianne M Perez; Subha Sen; Qingyu Wu; Edward F Plow; Carlo M Croce; Sadashiva Karnik
Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks.
The Journal of biological chemistry 2009;284(40):27487-99.
2009: Ewy A Mathé; Giang H Nguyen; Elise D Bowman; Yiqiang Zhao; Anuradha Budhu; Aaron J Schetter; Rosemary Braun; Mark Reimers; Kensuke Kumamoto; Duncan Hughes; Nasser K Altorki; Alan G Casson; Chang-gong liu; Xin Wei Wang; Nozomu Yanaihara; Nobutoshi Hagiwara; Andrew J Dannenberg; Masao Miyashita; Carlo M Croce; Curtis C Harris
MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6192-200.
2009: Carlo M Croce
Causes and consequences of microRNA dysregulation in cancer.
Nature reviews. Genetics 2009;10(10):704-14.
2009: Raffaele Baffa; Matteo Fassan; Stefano Volinia; Brian O'Hara; Chang-gong liu; Juan P Palazzo; Marina Gardiman; Massimo Rugge; Leonard G Gomella; Carlo M Croce; Anne Rosenberg
MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets.
The Journal of pathology 2009;219(2):214-21.
2009: Aaron J Schetter; Giang H Nguyen; Elise D Bowman; Ewy A Mathé; Siu Tsan Yuen; Jason E Hawkes; Carlo M Croce; Suet Yi Leung; Curtis C Harris
Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(18):5878-87.
2009: V Havelange; Ramiro Garzon; Carlo M Croce
MicroRNAs: new players in acute myeloid leukaemia.
British journal of cancer 2009;101(5):743-8.
2009: Alberto Izzotti; George A Calin; Vernon E Steele; Carlo M Croce; Silvio De Flora
Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):3243-50.
2009: shih-shih chen; Aparna Raval; Amy J Johnson; Erin Hertlein; Te-Hui Liu; Victor X Jin; Mara H Sherman; Shu-Jun Liu; David W Dawson; Katie E Williams; Mark Lanasa; Sandya Liyanarachchi; Thomas S Lin; Guido Marcucci; yuri pekarsky; Ramana V Davuluri; Carlo M Croce; Denis C Guttridge; Michael A Teitell; John C Byrd; Christoph Plass
Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13433-8.
2009: Alessandro Rimessi; Saverio Marchi; Carmen Fotino; Anna Romagnoli; Kay Huebner; Carlo M Croce; Paolo Pinton; Rosario Rizzuto
Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12753-8.
2009: Junfang Ji; Taro Yamashita; Anuradha Budhu; Marshonna Forgues; Hu-Liang Jia; Cuiling Li; Chuxia Deng; Elaine Wauthier; Lola M Reid; Qing-Hai Ye; Lun-Xiu Qin; Wen Yang; Hong-Yang Wang; Zhao-You Tang; Carlo M Croce; Xin Wei Wang
Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells.
Hepatology (Baltimore, Md.) 2009;50(2):472-80.
2009: Mark Bloomston; Jeffrey Kneile; Matthew Butterfield; Mary Dillhoff; Peter Muscarella; E Christopher Ellison; W Scott Melvin; Carlo M Croce; Flavia Pichiorri; Kay Huebner; Wendy L Frankel
Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical features.
Annals of surgical oncology 2009;16(8):2331-8.
2009: Masahiro Seike; Akiteru Goto; Tetsuya Okano; Elise D Bowman; Aaron J Schetter; Izumi Horikawa; Ewy A Mathe; Jin Jen; Ping Yang; Haruhiko Sugimura; Akihiko Gemma; Shoji Kudoh; Carlo M Croce; Curtis C Harris
MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):12085-90.
2009: Mark Chin; Mike J Mason; Wei Xie; Stefano Volinia; Mike Singer; Cory Peterson; Gayane Ambartsumyan; Otaren Aimiuwu; Laura Richter; Jin Zhang; Ivan Khvorostov; Vanessa Ott; Michael Grunstein; Neta Lavon; Nissim Benvenisty; Carlo M Croce; Amander T Clark; Tim Baxter; April D Pyle; Michael A Teitell; Matteo Pelegrini; Kathrin Plath; William Lowry
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.
Cell stem cell 2009;5(1):111-23.
2009: Nicola Valeri; Carlo M Croce; Muller Fabbri
Pathogenetic and clinical relevance of microRNAs in colorectal cancer.
Cancer genomics & proteomics 2009;6(4):195-204.
2009: Jerald P Radich; Andrew D Zelenetz; Wing C Chan; Carlo M Croce; Myron S Czuczman; Harry P Erba; Sandra J Horning; Jane Houldsworth; B Douglas Smith; David S Snyder; Hema M Sundar; Meir Wetzler; Jane N Winter
NCCN task force report: molecular markers in leukemias and lymphomas.
Journal of the National Comprehensive Cancer Network : JNCCN 2009;7 Suppl 4():S1-34, quiz S35-6.
2009: Hiroshi Okumura; Hideshi Ishii; Flavia Pichiorri; Carlo M Croce; Masaki Mori; Kay Huebner
Fragile gene product, Fhit, in oxidative and replicative stress responses.
Cancer science 2009;100(7):1145-50.
2009: Ramiro Garzon; Shujun Liu; Muller Fabbri; Zhongfa Liu; Catherine E A Heaphy; Elisa Callegari; Sebastian Schwind; Jiuxia Pang; Jianhua Yu; Natarajan Muthusamy; Violaine Havelange; Stefano Volinia; William Blum; Laura J Rush; Danilo Perrotti; Michael Andreeff; Clara D Bloomfield; John C Byrd; Kenneth Chan; Lai-Chu Wu; Carlo M Croce; Guido Marcucci
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.
Blood 2009;113(25):6411-8.
2009: Zhaoyong Li; Mohammad Q Hassan; Mohammed Jafferji; Rami I Aqeilan; Ramiro Garzon; Carlo M Croce; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation.
The Journal of biological chemistry 2009;284(23):15676-84.
2009: Guido Marcucci; Krzysztof Mrózek; Michael D Radmacher; Clara D Bloomfield; Carlo M Croce
MicroRNA expression profiling in acute myeloid and chronic lymphocytic leukaemias.
Best practice & research. Clinical haematology 2009;22(2):239-48.
2009: Asish K Ghosh; Tait D Shanafelt; Amelia Cimmino; Cristian Taccioli; Stefano Volinia; Chang-gong liu; George A Calin; Carlo M Croce; Denise A Chan; Amato J Giaccia; Charla Secreto; Linda E Wellik; Yean K Lee; Debabrata Mukhopadhyay; Neil E Kay
Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells.
Blood 2009;113(22):5568-74.
2009: Riccardo Spizzo; Milena S Nicoloso; Carlo M Croce; George A Calin
SnapShot: MicroRNAs in Cancer.
Cell 2009;137(3):586-586.e1.
2009: Paul A Northcott; Africa Fernandez-L; John Patrick Hagan; David W Ellison; Wesia Grajkowska; Yancey Gillespie; Richard Grundy; Timothy E van Meter; James T Rutka; Carlo M Croce; Anna Marie Kenney; Michael D Taylor
The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
Cancer research 2009;69(8):3249-55.
2009: Gullu Gorgun; Alan G Ramsay; Tobias A W Holderried; David Zahrieh; Rifca Le Dieu; Fenglong Liu; John Quackenbush; Carlo M Croce; John G Gribben
E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(15):6250-5.
2009: Francesco Trapasso; Rami I Aqeilan; Rodolfo Iuliano; Rosa Visone; Eugenio Gaudio; Laura Ciuffini; Hansjuerg Alder; francesco paduano; Giovanna Maria Pierantoni; Silvia Soddu; Carlo M Croce; Alfredo Fusco
Targeted disruption of the murine homeodomain-interacting protein kinase-2 causes growth deficiency in vivo and cell cycle arrest in vitro.
DNA and cell biology 2009;28(4):161-7.
2009: Rosa Visone; Carlo M Croce
MiRNAs and cancer.
The American journal of pathology 2009;174(4):1131-8.
2009: Ivana De Martino; Rosa Visone; Monica Fedele; Fabio Petrocca; Dario Palmieri; J Martinez Hoyos; Floriana Forzati; Carlo M Croce; Alfredo Fusco
Regulation of microRNA expression by HMGA1 proteins.
Oncogene 2009;28(11):1432-42.
2009: Marilena V Iorio; Patrizia Casalini; Claudia Piovan; Gianpiero Di Leva; Andrea Merlo; Tiziana Triulzi; Sylvie Ménard; Carlo M Croce; Elda Tagliabue
microRNA-205 regulates HER3 in human breast cancer.
Cancer research 2009;69(6):2195-200.
2009: Cristian Taccioli; Shao-Gui Wan; Chang-gong liu; Hansjuerg Alder; Stefano Volinia; John L Farber; Carlo M Croce; Louise Y Y Fong
Zinc replenishment reverses overexpression of the proinflammatory mediator S100A8 and esophageal preneoplasia in the rat.
Gastroenterology 2009;136(3):953-66.
2009: Rami I Aqeilan; John Patrick Hagan; Alain de Bruin; Maysoon Rawahneh; Zaidoun Salah; Eugenio Gaudio; Hasan Siddiqui; Stefano Volinia; Hansjuerg Alder; Jane B Lian; Gary S Stein; Carlo M Croce
Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis.
Endocrinology 2009;150(3):1530-5.
2009: Alberto Izzotti; George A Calin; Patrizio Arrigo; Vernon E Steele; Carlo M Croce; Silvio De Flora
Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(3):806-12.
2009: Muller Fabbri; Carlo M Croce; George A Calin
MicroRNAs in the ontogeny of leukemias and lymphomas.
Leukemia & lymphoma 2009;50(2):160-70.
2009: Flavia Pichiorri; Hiroshi Okumura; Tatsuya Nakamura; Preston N Garrison; Pierluigi Gasparini; Sung-Suk Suh; Teresa Druck; Kelly A McCorkell; Larry D Barnes; Carlo M Croce; Kay Huebner
Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.
The Journal of biological chemistry 2009;284(2):1040-9.
2009: Esmerina Tili; Carlo M Croce; Jean-Jacques Michaille
miR-155: on the crosstalk between inflammation and cancer.
International reviews of immunology 2009;28(5):264-84.
2009: Matteo Fassan; Raffaele Baffa; Juan P Palazzo; Joshua Lloyd; Marco Crosariol; Chang-gong liu; Stefano Volinia; Hannes Alder; Massimo Rugge; Carlo M Croce; Anne Rosenberg
MicroRNA expression profiling of male breast cancer.
Breast cancer research : BCR 2009;11(4):R58.
2009: Ramiro Garzon; George A Calin; Carlo M Croce
MicroRNAs in Cancer.
Annual review of medicine 2009;60():167-79.
2009: John Patrick Hagan; Brittany L O'Neill; Colin L Stewart; Serguei V Kozlov; Carlo M Croce
At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1.
PloS one 2009;4(2):e4352.
2009: Gerard J Nuovo; Terry S Elton; Patrick Nana-Sinkam; Stefano Volinia; Carlo M Croce; Thomas D Schmittgen
A methodology for the combined in situ analyses of the precursor and mature forms of microRNAs and correlation with their putative targets.
Nature protocols 2009;4(1):107-15.
2008: Matthew G Guenther; Lee N Lawton; Tatiana Rozovskaia; Garrett M Frampton; Stuart S Levine; Thomas L Volkert; Carlo M Croce; Tatsuya Nakamura; Eli Canaani; Richard A Young
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
Genes & development 2008;22(24):3403-8.
2008: Laura Gramantieri; Francesca Fornari; Elisa Callegari; Silvia Sabbioni; Giovanni Lanza; Carlo M Croce; Luigi Bolondi; Massimo Negrini
MicroRNA involvement in hepatocellular carcinoma.
Journal of cellular and molecular medicine 2008;12(6A):2189-204.
2008: Marilena V Iorio; Patrizia Casalini; Elda Tagliabue; Sylvie Ménard; Carlo M Croce
MicroRNA profiling as a tool to understand prognosis, therapy response and resistance in breast cancer.
European journal of cancer (Oxford, England : 1990) 2008;44(18):2753-9.
2008: Huating Wang; Ramiro Garzon; Hao Sun; Katherine J Ladner; Ravi Singh; Jason Dahlman; Alfred Cheng; Brett M Hall; Stephen J Qualman; Dawn Chandler; Carlo M Croce; Denis C Guttridge
NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma.
Cancer cell 2008;14(5):369-81.
2008: Barbara Quaresima; Francesco Romeo; Maria C Faniello; Maddalena Di Sanzo; Chang-gong liu; Annamaria Lavecchia; Cristian Taccioli; Eugenio Gaudio; francesco baudi; Francesco Trapasso; Carlo M Croce; Giovanni Cuda; Francesco Costanzo
BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(21):6797-803.
2008: Fang Lu; Andreas Weidmer; Chang-gong liu; Stefano Volinia; Carlo M Croce; Paul M Lieberman
Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence.
Journal of virology 2008;82(21):10436-43.
2008: Fabio Petrocca; Aldo Vecchione; Carlo M Croce
Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling.
Cancer research 2008;68(20):8191-4.
2008: Esmerina Tili; Jean-Jacques Michaille; Stefan Costinean; Carlo M Croce
MicroRNAs, the immune system and rheumatic disease.
Nature clinical practice. Rheumatology 2008;4(10):534-41.
2008: Fabio Fornari; Laura Gramantieri; Manuela Ferracin; Angelo Veronese; Silvia Sabbioni; George A Calin; G L Grazi; Catia Giovannini; Carlo M Croce; Luigi Bolondi; Massimo Negrini
MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma.
Oncogene 2008;27(43):5651-61.
2008: Zhaoyong Li; Mohammad Q Hassan; Stefano Volinia; Andre J van Wijnen; Janet L Stein; Carlo M Croce; Jane B Lian; Gary S Stein
A microRNA signature for a BMP2-induced osteoblast lineage commitment program.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13906-11.
2008: amaia lujambio; George A Calin; Alberto Villanueva; Santiago Ropero; Montserrat Sánchez-Céspedes; David Blanco; Luis M Montuenga; Simona Rossi; Milena S Nicoloso; William J Faller; William M Gallagher; Suzanne A Eccles; Carlo M Croce; Manel Esteller
A microRNA DNA methylation signature for human cancer metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13556-61.
2008: Flavia Pichiorri; Sung-Suk Suh; marco ladetto; Michael Kuehl; Tiziana Palumbo; Daniela Drandi; Cristian Taccioli; nicola zanesi; Hansjuerg Alder; John Patrick Hagan; Reinhold Munker; Stefano Volinia; Mario Boccadoro; Ramiro Garzon; Antonio Palumbo; Rami I Aqeilan; Carlo M Croce
MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):12885-90.
2008: Shan Deng; George Adrian Calin; Carlo M Croce; George Coukos; Lin Zhang
Mechanisms of microRNA deregulation in human cancer.
Cell cycle (Georgetown, Tex.) 2008;7(17):2643-6.
2008: Brian A McCarthy; Erin Boyle; Xue Ping Wang; Dorothy Guzowski; Santanu Paul; Rosa Catera; Joshua Trott; Joy (Xiao-Jie) Yan; Carlo M Croce; Rajendra N Damle; Sophia Yancopoulos; Bradley T Messmer; Martin Lesser; Steven Allen; Kanti Rai; Nicholas Chiorazzi
Surface expression of Bcl-2 in chronic lymphocytic leukemia and other B-cell leukemias and lymphomas without a breakpoint t(14;18).
Molecular medicine (Cambridge, Mass.) 2008;14(9-10):618-27.
2008: Stefan Ambs; Robyn L Prueitt; Ming Yi; Robert S Hudson; Tiffany M Howe; Fabio Petrocca; Tiffany A Wallace; Chang-gong liu; Stefano Volinia; George A Calin; Harris G Yfantis; Robert M Stephens; Carlo M Croce
Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer.
Cancer research 2008;68(15):6162-70.
2008: Jenny C Lee; Daphna Weissglas-Volkov; Mira Kyttälä; Zari Dastani; Rita M Cantor; Eric M Sobel; Christopher Plaisier; James C Engert; Marleen M J van Greevenbroek; John P Kane; Mary J Malloy; Clive R Pullinger; Adriana Huertas-Vazquez; Carlos Aguilar Salinas; Teresa Tusie-Luna; Tjerk W A de Bruin; Bradley E Aouizerat; Carla C J van der Kallen; Carlo M Croce; Rami I Aqeilan; Michel Marcil; Jorma S A Viikari; Terho Lehtimäki; Olli T Raitakari; Johanna Kuusisto; Markku Laakso; Marja-Riitta Taskinen; Jacques Genest; Päivi Pajukanta
WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.
American journal of human genetics 2008;83(2):180-92.
2008: Rami I Aqeilan; Mohammad Q Hassan; Alain de Bruin; John Patrick Hagan; Stefano Volinia; Titziana Palumbo; Sadiq Hussain; Suk-Hee Lee; Tripti Gaur; Gary S Stein; Jane B Lian; Carlo M Croce
The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism.
The Journal of biological chemistry 2008;283(31):21629-39.
2008: Robyn L Prueitt; Ming Yi; Robert S Hudson; Tiffany A Wallace; Tiffany M Howe; Harris G Yfantis; Dong H Lee; Robert M Stephens; Chang-gong liu; George A Calin; Carlo M Croce; Stefan Ambs
Expression of microRNAs and protein-coding genes associated with perineural invasion in prostate cancer.
The Prostate 2008;68(11):1152-64.
2008: Jharna Datta; Huban Kutay; Mohd W Nasser; Gerard J Nuovo; Bo Wang; Sarmila Majumder; Chang-gong liu; Stefano Volinia; Carlo M Croce; Thomas D Schmittgen; Kalpana Ghoshal; Samson T Jacob
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.
Cancer research 2008;68(13):5049-58.
2008: Ramiro Garzon; Carlo M Croce
MicroRNAs in normal and malignant hematopoiesis.
Current opinion in hematology 2008;15(4):352-8.
2008: M Garofalo; C Quintavalle; G Di Leva; C Zanca; Giovanni Romano; C Taccioli; Chang-gong liu; Carlo M Croce; Gianluigi Condorelli
MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer.
Oncogene 2008;27(27):3845-55.
2008: María J Bueno; Ignacio Perez de Castro; Marta Gómez de Cedrón; Javier Santos; George A Calin; Juan C Cigudosa; Carlo M Croce; José Fernández-Piqueras; Marcos Malumbres
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.
Cancer cell 2008;13(6):496-506.
2008: Carlo M Croce
MicroRNAs and lymphomas.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19 Suppl 4():iv39-40.
2008: Francesco Trapasso; Flavia Pichiorri; Marco Gaspari; Tiziana Palumbo; Rami I Aqeilan; Eugenio Gaudio; Hiroshi Okumura; Rodolfo Iuliano; Giampiero Di Leva; Muller Fabbri; David E Birk; Cinzia Raso; Kari Green-Church; Luigi G Spagnoli; Salvatore Venuta; Kay Huebner; Carlo M Croce
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
The Journal of biological chemistry 2008;283(20):13736-44.
2008: Guido Marcucci; Michael D Radmacher; Kati Maharry; Krzysztof Mrózek; Amy S Ruppert; Peter Paschka; Tamara Vukosavljevic; Susan P Whitman; Claudia D Baldus; Christian Langer; Chang-gong liu; Andrew J Carroll; Bayard L Powell; Ramiro Garzon; Carlo M Croce; Jonathan E Kolitz; Michael A Caligiuri; Richard A Larson; Clara D Bloomfield
MicroRNA expression in cytogenetically normal acute myeloid leukemia.
The New England journal of medicine 2008;358(18):1919-28.
2008: Ricardo Medina; Sayyed K Zaidi; Chang-gong liu; Janet L Stein; Andre J van Wijnen; Carlo M Croce; Gary S Stein
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival.
Cancer research 2008;68(8):2773-80.
2008: George A Calin; Amelia Cimmino; Muller Fabbri; Manuela Ferracin; Sylwia E Wojcik; Masayoshi Shimizu; Cristian Taccioli; nicola zanesi; Ramiro Garzon; Rami I Aqeilan; Hansjuerg Alder; Stefano Volinia; Laura Rassenti; Xiuping Liu; Chang-gong liu; Thomas Kipps; Massimo Negrini; Carlo M Croce
MiR-15a and miR-16-1 cluster functions in human leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(13):5166-71.
2008: Raffaele Baffa; Matteo Fassan; Cinzia Sevignani; Aldo Vecchione; Hideshi Ishii; Enrico Giarnieri; Renato V Iozzo; Leonard G Gomella; Carlo M Croce
Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.
Carcinogenesis 2008;29(4):846-8.
2008: Maria Sundvall; Anna Korhonen; Ilkka Paatero; Eugenio Gaudio; Gerry Melino; Carlo M Croce; Rami I Aqeilan; Klaus Elenius
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4162-7.
2008: Ramiro Garzon; Stefano Volinia; Chang-gong liu; Cecilia Fernandez-Cymering; Tiziana Palumbo; Flavia Pichiorri; Muller Fabbri; Kevin Coombes; Hansjuerg Alder; Tatsuya Nakamura; Neal Flomenberg; Guido Marcucci; George A Calin; Steven M Kornblau; Andrew Lamb; Clara D Bloomfield; Michael Andreeff; Carlo M Croce
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.
Blood 2008;111(6):3183-9.
2008: Ramiro Garzon; Michela Garofalo; Maria Paola Martelli; Roger Briesewitz; Lisheng Wang; Cecilia Fernandez-Cymering; Stefano Volinia; Chang-gong liu; Susanne Schnittger; Torsten Haferlach; Arcangelo Liso; Daniela Diverio; Marco Mancini; Giovanna Meloni; Robin Foa; Massimo F Martelli; Cristina Mecucci; Carlo M Croce; Brunangelo Falini
Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3945-50.
2008: Fabio Petrocca; Rosa Visone; Mariadele Rapazzotti Onelli; Manisha H Shah; Milena S Nicoloso; Ivana de Martino; Dimitrios Iliopoulos; Emanuela Pilozzi; Chang-gong liu; Massimo Negrini; Luigi Cavazzini; Stefano Volinia; Hansjuerg Alder; Luigi P Ruco; Gustavo Baldassarre; Carlo M Croce; Aldo Vecchione
E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer.
Cancer cell 2008;13(3):272-86.
2008: Anuradha Budhu; Hu-Liang Jia; Marshonna Forgues; Chang-gong liu; David S Goldstein; Amy Lam; Krista A Zanetti; Qing-Hai Ye; Lun-Xiu Qin; Carlo M Croce; Zhao-You Tang; Xin Wei Wang
Identification of metastasis-related microRNAs in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2008;47(3):897-907.
2008: Carlo M Croce
Oncogenes and cancer.
The New England journal of medicine 2008;358(5):502-11.
2008: Aaron J Schetter; Suet Yi Leung; Jane J Sohn; Krista A Zanetti; Elise D Bowman; Nozomu Yanaihara; Siu Tsan Yuen; Tsun Leung Chan; Dora L W Kwong; Gordon K H Au; Chang-gong liu; George A Calin; Carlo M Croce; Curtis C Harris
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.
JAMA : the journal of the American Medical Association 2008;299(4):425-36.
2008: Michela Garofalo; Cristina Quintavalle; Ciro Zanca; Assunta De Rienzo; Giulia Romano; Mario Acunzo; Loredana Puca; Mariarosaria Incoronato; Carlo M Croce; Gerolama Condorelli
Akt regulates drug-induced cell death through Bcl-w downregulation.
PloS one 2008;3(12):e4070.
2008: Stefano Volinia; Nicoletta Mascellani; Jlenia Marchesini; Angelo Veronese; Elizabeth Ormondroyd; Hansjuerg Alder; Jeff Palatini; Massimo Negrini; Carlo M Croce
Genome wide identification of recessive cancer genes by combinatorial mutation analysis.
PloS one 2008;3(10):e3380.
2008: Chang-gong liu; George A Calin; Stefano Volinia; Carlo M Croce
MicroRNA expression profiling using microarrays.
Nature protocols 2008;3(4):563-78.
2008: Muller Fabbri; Carlo M Croce; George A Calin
MicroRNAs.
Cancer journal (Sudbury, Mass.) 2008;14(1):1-6.
2008: Paul E Blower; Ji-Hyun Chung; Joseph S Verducci; Shili Lin; Jong-Kook Park; Zunyan Dai; Chang-gong liu; Thomas D Schmittgen; William C Reinhold; Carlo M Croce; John N Weinstein; Wolfgang Sadee
MicroRNAs modulate the chemosensitivity of tumor cells.
Molecular cancer therapeutics 2008;7(1):1-9.
2008: Rosa Visone; Rodolfo Iuliano; Dario Palmieri; Ilter Nurettin Server; Gennaro Chiappetta; Ivana De Martino; Monica Fedele; Stefan Costinean; Tatiana M Oberyszyn; Donna F Kusewitt; Carlo M Croce; Alfredo Fusco
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
European journal of cancer (Oxford, England : 1990) 2008;44(2):318-25.
2007: Milena S Nicoloso; Thomas Kipps; Carlo M Croce; George A Calin
MicroRNAs in the pathogeny of chronic lymphocytic leukaemia.
British journal of haematology 2007;139(5):709-16.
2007: Rosa Visone; pierlorenzo pallante; Aldo Vecchione; R Cirombella; Manuela Ferracin; Angelo Ferraro; Stefano Volinia; S Coluzzi; Vincenza Leone; Eleonora Borbone; Chang-gong liu; Fabio Petrocca; Giancarlo Troncone; George A Calin; Aldo Scarpa; C Colato; Giovanni Tallini; Massimo Santoro; Carlo M Croce; Alfredo Fusco
Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.
Oncogene 2007;26(54):7590-5.
2007: Irene M Pedersen; Guofeng Cheng; Stefan Wieland; Stefano Volinia; Carlo M Croce; Francis V Chisari; Michael David
Interferon modulation of cellular microRNAs as an antiviral mechanism.
Nature 2007;449(7164):919-22.
2007: Muller Fabbri; Ramiro Garzon; Amelia Cimmino; Zhongfa Liu; nicola zanesi; Elisa Callegari; Shujun Liu; Hansjuerg Alder; Stefan Costinean; Cecilia Fernandez-Cymering; Stefano Volinia; Gulnur Guler; Carl D Morrison; Kenneth K Chan; Guido Marcucci; George A Calin; Kay Huebner; Carlo M Croce
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15805-10.
2007: Rami I Aqeilan; Valentina Donati; Eugenio Gaudio; Milena S Nicoloso; Maria Sundvall; Anna Korhonen; Johan Lundin; Jorma Isola; Marius Sudol; Heikki Joensuu; Carlo M Croce; Klaus Elenius
Association of Wwox with ErbB4 in breast cancer.
Cancer research 2007;67(19):9330-6.
2007: Marilena V Iorio; Rosa Visone; Gianpiero Di Leva; Valentina Donati; Fabio Petrocca; Patrizia Casalini; Cristian Taccioli; Stefano Volinia; Chang-gong liu; Hansjuerg Alder; George A Calin; Sylvie Ménard; Carlo M Croce
MicroRNA signatures in human ovarian cancer.
Cancer research 2007;67(18):8699-707.
2007: Hiroshi Nakanishi; Tatsuya Nakamura; Eli Canaani; Carlo M Croce
ALL1 fusion proteins induce deregulation of EphA7 and ERK phosphorylation in human acute leukemias.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14442-7.
2007: Gustavo Baldassarre; Carlo M Croce; Andrea Vecchione
Take your "M" time.
Cell cycle (Georgetown, Tex.) 2007;6(17):2087-90.
2007: Fedra Gottardo; Chang-gong liu; Manuela Ferracin; George A Calin; Matteo Fassan; Pierfrancesco Bassi; Cinzia Sevignani; Dolores Byrne; Massimo Negrini; Francesco Pagano; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
Micro-RNA profiling in kidney and bladder cancers.
Urologic oncology 2007;25(5):387-92.
2007: George A Calin; Chang-gong liu; Manuela Ferracin; Terry Hyslop; Riccardo Spizzo; Cinzia Sevignani; Muller Fabbri; Amelia Cimmino; Eun Joo Lee; Sylwia E Wojcik; Masayoshi Shimizu; Esmerina Tili; Simona Rossi; Cristian Taccioli; Flavia Pichiorri; Xiuping Liu; Simona Zupo; Vlad Herlea; Laura Gramantieri; Roberta Gafà; Hansjuerg Alder; Laura Rassenti; Stefano Volinia; Thomas D Schmittgen; Thomas Kipps; Massimo Negrini; Carlo M Croce
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas.
Cancer cell 2007;12(3):215-29.
2007: George A Calin; yuri pekarsky; Carlo M Croce
The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia.
Best practice & research. Clinical haematology 2007;20(3):425-37.
2007: Sai Yendamuri; Francesco Trapasso; Manuela Ferracin; Rossano Cesari; Cinzia Sevignani; Masayoshi Shimizu; Shashi Rattan; Tamotsu Kuroki; Kristoffel R Dumon; Florencia Bullrich; Chang-gong liu; Massimo Negrini; Noel N Williams; Larry R Kaiser; Carlo M Croce; George A Calin
Tumor suppressor functions of ARLTS1 in lung cancers.
Cancer research 2007;67(16):7738-45.
2007: George A Calin; Carlo M Croce
Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications.
The Journal of clinical investigation 2007;117(8):2059-66.
2007: Rami I Aqeilan; Carlo M Croce
WWOX in biological control and tumorigenesis.
Journal of cellular physiology 2007;212(2):307-10.
2007: Andrew Oberst; Martina Malatesta; Rami I Aqeilan; Mario Rossi; Paolo Salomoni; Rodolfo Murillas; Prashant Sharma; Michael R Kuehn; Moshe Oren; Carlo M Croce; Francesca Bernassola; Gerry Melino
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(27):11280-5.
2007: Laura Gramantieri; Manuela Ferracin; Francesca Fornari; Angelo Veronese; Silvia Sabbioni; Chang-gong liu; George A Calin; Catia Giovannini; Eros Ferrazzi; Gian Luca Grazi; Carlo M Croce; Luigi Bolondi; Massimo Negrini
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma.
Cancer research 2007;67(13):6092-9.
2007: Laura Fontana; Elvira Pelosi; Paolo Greco; Serena Racanicchi; Ugo Testa; Francesca Liuzzi; Carlo M Croce; Ercole Brunetti; Francesco Grignani; Cesare Peschle
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation.
Nature cell biology 2007;9(7):775-87.
2007: Berna S Sayan; emre sayan; Ai Li Yang; Rami I Aqeilan; Eleonora Candi; Gerald M Cohen; Richard A Knight; Carlo M Croce; Gerry Melino
Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(26):10871-6.
2007: Tatsuya Nakamura; Eli Canaani; Carlo M Croce
Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(26):10980-5.
2007: Rami I Aqeilan; John Patrick Hagan; Haifa A Aqeilan; Flavia Pichiorri; Louise Y Y Fong; Carlo M Croce
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
Cancer research 2007;67(12):5606-10.
2007: Ramiro Garzon; Flavia Pichiorri; Tiziana Palumbo; M Visentini; Rami I Aqeilan; Amelia Cimmino; H Wang; H Sun; Stefano Volinia; Hansjuerg Alder; George A Calin; Chang-gong liu; Michael Andreeff; Carlo M Croce
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia.
Oncogene 2007;26(28):4148-57.
2007: Massimo Negrini; Manuela Ferracin; Silvia Sabbioni; Carlo M Croce
MicroRNAs in human cancer: from research to therapy.
Journal of cell science 2007;120(Pt 11):1833-40.
2007: Cinzia Sevignani; George A Calin; Stephanie C Nnadi; Masayoshi Shimizu; Ramana V Davuluri; Terry Hyslop; Peter Demant; Carlo M Croce; Linda D Siracusa
MicroRNA genes are frequently located near mouse cancer susceptibility loci.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):8017-22.
2007: Mark Bloomston; Wendy L Frankel; Fabio Petrocca; Stefano Volinia; Hansjuerg Alder; John Patrick Hagan; Chang-gong liu; Darshna Bhatt; Cristian Taccioli; Carlo M Croce
MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.
JAMA : the journal of the American Medical Association 2007;297(17):1901-8.
2007: Paul E Blower; Joseph S Verducci; Shili Lin; Jin Zhou; Ji-Hyun Chung; Zunyan Dai; Chang-gong liu; William C Reinhold; Philip L Lorenzi; Eric P Kaldjian; Carlo M Croce; John N Weinstein; Wolfgang Sadee
MicroRNA expression profiles for the NCI-60 cancer cell panel.
Molecular cancer therapeutics 2007;6(5):1483-91.
2007: Alessandra Carè; Daniele Catalucci; Federica Felicetti; Désirée Bonci; Antonio Addario; Paolo Gallo; Marie-Louise Bang; Patrizia Segnalini; Yusu Gu; Nancy Dalton; Leonardo Elia; Michael V G Latronico; Morten A Høydal; Camillo Autore; Matteo A Russo; Gerald W Dorn; Oyvind Ellingsen; Pilar Ruiz-Lozano; Kirk L Peterson; Carlo M Croce; Cesare Peschle; Gianluigi Condorelli
MicroRNA-133 controls cardiac hypertrophy.
Nature medicine 2007;13(5):613-8.
2007: yuri pekarsky; nicola zanesi; Rami I Aqeilan; Carlo M Croce
Animal models for chronic lymphocytic leukemia.
Journal of cellular biochemistry 2007;100(5):1109-18.
2007: Rami I Aqeilan; Francesco Trapasso; Sadiq Hussain; Stefan Costinean; Dean Marshall; yuri pekarsky; John Patrick Hagan; nicola zanesi; Mohamed Kaou; Gary S Stein; Jane B Lian; Carlo M Croce
Targeted deletion of Wwox reveals a tumor suppressor function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):3949-54.
2007: Aldo Vecchione; Gustavo Baldassarre; Hideshi Ishii; Milena S Nicoloso; Barbara Belletti; Fabio Petrocca; nicola zanesi; Louise Y Y Fong; Sabrina Battista; Daniela Guarnieri; Raffaele Baffa; Hansjuerg Alder; John L Farber; Peter J Donovan; Carlo M Croce
Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.
Cancer cell 2007;11(3):275-89.
2007: Ritu Kulshreshtha; Manuela Ferracin; Sylwia E Wojcik; Ramiro Garzon; Hansjuerg Alder; Francisco J Agosto-Perez; Ramana V Davuluri; Chang-gong liu; Carlo M Croce; Massimo Negrini; George A Calin; Mircea Ivan
A microRNA signature of hypoxia.
Molecular and cellular biology 2007;27(5):1859-67.
2007: Irina Issaeva; Yulia Zonis; Tanya Rozovskaia; Kira Orlovsky; Carlo M Croce; Tatsuya Nakamura; Alexander Mazo; Lea Eisenbach; Eli Canaani
Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.
Molecular and cellular biology 2007;27(5):1889-903.
2007: Robert W Georgantas; Richard Hildreth; Sebastien Morisot; Jonathan Alder; Chang-gong liu; Shelly Heimfeld; George A Calin; Carlo M Croce; Curt I Civin
CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2750-5.
2007: Silvio De Flora; Francesco D'Agostini; Alberto Izzotti; nicola zanesi; Carlo M Croce; sandra mulbah
Molecular and cytogenetical alterations induced by environmental cigarette smoke in mice heterozygous for Fhit.
Cancer research 2007;67(3):1001-6.
2007: Arianna Bottoni; Maria Chiara Zatelli; Manuela Ferracin; Federico Tagliati; Daniela Piccin; Cristina Vignali; George A Calin; Massimo Negrini; Carlo M Croce; Ettore C degli Uberti
Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas.
Journal of cellular physiology 2007;210(2):370-7.
2007: Nicoletta Mascellani; Xiuping Liu; Simona Rossi; Jlenia Marchesini; Davide Valentini; Diego Arcelli; Cristian Taccioli; Mauro Helmer Citterich; Chang-gong liu; Rita Evangelisti; Giandomenico Russo; Jorge M Santos; Carlo M Croce; Stefano Volinia
Compatible solutes from hyperthermophiles improve the quality of DNA microarrays.
BMC biotechnology 2007;7():82.
2007: John Patrick Hagan; Carlo M Croce
MicroRNAs in carcinogenesis.
Cytogenetic and genome research 2007;118(2-4):252-9.
2007: Kelly A McCorkell; Rita Mancini; Z Siprashvili; B L Barnoski; Dimitrios Iliopoulos; Linda D Siracusa; nicola zanesi; Carlo M Croce; Louise Y Y Fong; Teresa Druck; Kay Huebner
Influence of a nonfragile FHIT transgene on murine tumor susceptibility.
Cytogenetic and genome research 2007;118(2-4):196-203.
2007: Aldo Vecchione; Carlo M Croce; Gustavo Baldassarre
Fez1/Lzts1 a new mitotic regulator implicated in cancer development.
Cell division 2007;2():24.
2007: Giovanni Lanza; Manuela Ferracin; Roberta Gafà; Angelo Veronese; Riccardo Spizzo; Flavia Pichiorri; Chang-gong liu; George A Calin; Carlo M Croce; Massimo Negrini
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer.
Molecular cancer 2007;6():54.
2006: yuri pekarsky; Urmila Santanam; Amelia Cimmino; Alexey Palamarchuk; Alexey Efanov; Vadim Maximov; Stefano Volinia; Hansjuerg Alder; Chang-gong liu; Laura Rassenti; George A Calin; John Patrick Hagan; Thomas Kipps; Carlo M Croce
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181.
Cancer research 2006;66(24):11590-3.
2006: Eugenio Gaudio; Alexey Palamarchuk; Tiziana Palumbo; Francesco Trapasso; yuri pekarsky; Carlo M Croce; Rami I Aqeilan
Physical association with WWOX suppresses c-Jun transcriptional activity.
Cancer research 2006;66(24):11585-9.
2006: Hideshi Ishii; Koshi Mimori; Hiroshi Inoue; Taeko Inageta; Kazuhiro Ishikawa; Shuho Semba; Teresa Druck; Francesco Trapasso; Kenzaburo Tani; Andrea Vecchione; Carlo M Croce; Masaki Mori; Kay Huebner
Fhit modulates the DNA damage checkpoint response.
Cancer research 2006;66(23):11287-92.
2006: Ramiro Garzon; Muller Fabbri; Amelia Cimmino; George A Calin; Carlo M Croce
MicroRNA expression and function in cancer.
Trends in molecular medicine 2006;12(12):580-7.
2006: Fabio Petrocca; Dimitrios Iliopoulos; Haiyan R Qin; Milena S Nicoloso; Sai Yendamuri; Sylwia E Wojcik; Masayoshi Shimizu; Gianpiero Di Leva; Aldo Vecchione; Francesco Trapasso; Andrew K Godwin; Massimo Negrini; George A Calin; Carlo M Croce
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
Cancer research 2006;66(21):10287-91.
2006: George A Calin; Carlo M Croce
MicroRNA signatures in human cancers.
Nature reviews. Cancer 2006;6(11):857-66.
2006: Claudia Roldo; Edoardo Missiaglia; John Patrick Hagan; Massimo Falconi; Paola Capelli; Samantha Bersani; George A Calin; Stefano Volinia; Chang-gong liu; Aldo Scarpa; Carlo M Croce
MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(29):4677-84.
2006: George A Calin; Carlo M Croce
MicroRNAs and chromosomal abnormalities in cancer cells.
Oncogene 2006;25(46):6202-10.
2006: Shuho Semba; Shuang-Yin Han; Haiyan R Qin; Kelly A McCorkell; Dimitrios Iliopoulos; yuri pekarsky; Teresa Druck; Francesco Trapasso; Carlo M Croce; Kay Huebner
Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor.
The Journal of biological chemistry 2006;281(38):28244-53.
2006: Mario Rossi; Rami I Aqeilan; Michael Neale; Eleonora Candi; Paolo Salomoni; Richard A Knight; Carlo M Croce; Gerry Melino
The E3 ubiquitin ligase Itch controls the protein stability of p63.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(34):12753-8.
2006: Amy J Johnson; David M Lucas; Natarajan Muthusamy; Lisa L Smith; Ryan B Edwards; Michael D De Lay; Carlo M Croce; Michael R Grever; John C Byrd
Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia.
Blood 2006;108(4):1334-8.
2006: Joy (Xiao-Jie) Yan; Emilia Albesiano; nicola zanesi; Sophia Yancopoulos; Alan Sawyer; Egidio Romano; Aleksandar Petlichkovski; Dimitar G Efremov; Carlo M Croce; Nicholas Chiorazzi
B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11713-8.
2006: Haiyan R Qin; Dimitrios Iliopoulos; Shuho Semba; Muller Fabbri; Teresa Druck; Stefano Volinia; Carlo M Croce; Carl D Morrison; Russell D Klein; Kay Huebner
A role for the WWOX gene in prostate cancer.
Cancer research 2006;66(13):6477-81.
2006: Alexey Palamarchuk; nicola zanesi; Rami I Aqeilan; Alexey Efanov; Vadim Maximov; Urmila Santanam; John Patrick Hagan; Carlo M Croce; yuri pekarsky
Tal1 transgenic expression reveals absence of B lymphocytes.
Cancer research 2006;66(12):6014-7.
2006: Gianpiero Di Leva; George A Calin; Carlo M Croce
MicroRNAs: fundamental facts and involvement in human diseases.
Birth defects research. Part C, Embryo today : reviews 2006;78(2):180-9.
2006: Francesco Trapasso; Alessandra Drusco; Stefan Costinean; Hansjuerg Alder; Rami I Aqeilan; Rodolfo Iuliano; Eugenio Gaudio; Cinzia Raso; nicola zanesi; Carlo M Croce; Alfredo Fusco
Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis.
DNA and cell biology 2006;25(6):376-82.
2006: Flavia Pichiorri; Francesco Trapasso; Tiziana Palumbo; Rami I Aqeilan; Alessandra Drusco; Bradley W Blaser; Dimitrios Iliopoulos; Michael A Caligiuri; Kay Huebner; Carlo M Croce
Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3494-501.
2006: pierlorenzo pallante; Rosa Visone; Manuela Ferracin; Angelo Ferraro; Maria Teresa Berlingieri; Giancarlo Troncone; Gennaro Chiappetta; Chang-gong liu; Massimo Santoro; Massimo Negrini; Carlo M Croce; Alfredo Fusco
MicroRNA deregulation in human thyroid papillary carcinomas.
Endocrine-related cancer 2006;13(2):497-508.
2006: sandra mulbah; Francesco D'Agostini; Gancho Ganchev; Alberto Izzotti; Barbara Di Marco; Ronald A Lubet; nicola zanesi; Carlo M Croce; Silvio De Flora
Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7823-8.
2006: Shuho Semba; Francesco Trapasso; Muller Fabbri; Kelly A McCorkell; Stefano Volinia; Teresa Druck; Dimitrios Iliopoulos; yuri pekarsky; H Ishii; Preston N Garrison; Larry D Barnes; Carlo M Croce; Kay Huebner
Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.
Oncogene 2006;25(20):2860-72.
2006: Stefan Costinean; nicola zanesi; yuri pekarsky; Esmerina Tili; Stefano Volinia; Nyla A Heerema; Carlo M Croce
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(18):7024-9.
2006: Francesco D'Agostini; Alberto Izzotti; sandra mulbah; nicola zanesi; Carlo M Croce; Silvio De Flora
Early loss of Fhit in the respiratory tract of rodents exposed to environmental cigarette smoke.
Cancer research 2006;66(7):3936-41.
2006: Ramiro Garzon; Flavia Pichiorri; Tiziana Palumbo; Rodolfo Iuliano; Amelia Cimmino; Rami I Aqeilan; Stefano Volinia; Darshna Bhatt; Hansjuerg Alder; Guido Marcucci; George A Calin; Chang-gong liu; Clara D Bloomfield; Michael Andreeff; Carlo M Croce
MicroRNA fingerprints during human megakaryocytopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(13):5078-83.
2006: Nozomu Yanaihara; Natasha J Caplen; Elise Bowman; Masahiro Seike; Kensuke Kumamoto; Ming Yi; Robert M Stephens; Aikou Okamoto; Jun Yokota; Tadao Tanaka; George A Calin; Chang-gong liu; Carlo M Croce; Curtis C Harris
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis.
Cancer cell 2006;9(3):189-98.
2006: Cinzia Sevignani; George A Calin; Linda D Siracusa; Carlo M Croce
Mammalian microRNAs: a small world for fine-tuning gene expression.
Mammalian genome : official journal of the International Mammalian Genome Society 2006;17(3):189-202.
2006: Monica Fedele; Vincenzo Fidanza; Sabrina Battista; Francesca Pentimalli; Andres J P Klein-Szanto; Rosa Visone; Ivana De Martino; Antonio Curcio; Carmine Morisco; Luigi Del Vecchio; Gustavo Baldassarre; Claudio Arra; Giuseppe Viglietto; Ciro Indolfi; Carlo M Croce; Alfredo Fusco
Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.
Cancer research 2006;66(5):2536-43.
2006: Stefano Volinia; George A Calin; Chang-gong liu; Stefan Ambs; Amelia Cimmino; Fabio Petrocca; Rosa Visone; Marilena V Iorio; Claudia Roldo; Manuela Ferracin; Robyn L Prueitt; Nozomu Yanaihara; Roberta Gafà; Aldo Scarpa; Aldo Vecchione; Massimo Negrini; Curtis C Harris; Carlo M Croce
A microRNA expression signature of human solid tumors defines cancer gene targets.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2257-61.
2006: nicola zanesi; Rami I Aqeilan; Alessandra Drusco; Mohamed Kaou; Cinzia Sevignani; Stefan Costinean; Laura Bortesi; Gaspare La Rocca; Pavel Koldovsky; Stefano Volinia; Rita Mancini; George A Calin; Charles Scott; yuri pekarsky; Carlo M Croce
Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
Cancer research 2006;66(2):915-20.
2005: Huiling He; Krystian Jazdzewski; Wei Li; Sandya Liyanarachchi; Rebecca Nagy; Stefano Volinia; George A Calin; Chang-gong liu; Kaarle Franssila; Saul Suster; Richard T Kloos; Carlo M Croce; Albert de La Chapelle
The role of microRNA genes in papillary thyroid carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(52):19075-80.
2005: Alexey Palamarchuk; Alexey Efanov; Vadim Maximov; Rami I Aqeilan; Carlo M Croce; yuri pekarsky
Akt phosphorylates and regulates Pdcd4 tumor suppressor protein.
Cancer research 2005;65(24):11282-6.
2005: Nadia Felli; Laura Fontana; Elvira Pelosi; Rosanna Botta; Désirée Bonci; francesco facchiano; Francesca Liuzzi; Valentina Lulli; Ornella Morsilli; Simona Santoro; Mauro Valtieri; George A Calin; Chang-gong liu; Antonio Sorrentino; Carlo M Croce; Cesare Peschle
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):18081-6.
2005: nicola zanesi; yuri pekarsky; Carlo M Croce
A mouse model of the fragile gene FHIT: From carcinogenesis to gene therapy and cancer prevention.
Mutation research 2005;591(1-2):103-9.
2005: George A Calin; Manuela Ferracin; Amelia Cimmino; Gianpiero Di Leva; Masayoshi Shimizu; Sylwia E Wojcik; Marilena V Iorio; Rosa Visone; Nurettin Ilfer Sever; Muller Fabbri; Rodolfo Iuliano; Tiziana Palumbo; Flavia Pichiorri; Claudia Roldo; Ramiro Garzon; Cinzia Sevignani; Laura Rassenti; Hansjuerg Alder; Stefano Volinia; Chang-gong liu; Thomas Kipps; Massimo Negrini; Carlo M Croce
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia.
The New England journal of medicine 2005;353(17):1793-801.
2005: Muller Fabbri; Dimitrios Iliopoulos; Francesco Trapasso; Rami I Aqeilan; Amelia Cimmino; nicola zanesi; Sai Yendamuri; Shuang-Yin Han; Dino Amadori; Kay Huebner; Carlo M Croce
WWOX gene restoration prevents lung cancer growth in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15611-6.
2005: Gustavo Baldassarre; Barbara Belletti; Sabrina Battista; Milena S Nicoloso; Francesca Pentimalli; Monica Fedele; Carlo M Croce; Alfredo Fusco
HMGA1 protein expression sensitizes cells to cisplatin-induced cell death.
Oncogene 2005;24(45):6809-19.
2005: Amelia Cimmino; George A Calin; Muller Fabbri; Marilena V Iorio; Manuela Ferracin; Masayoshi Shimizu; Sylwia E Wojcik; Rami I Aqeilan; Simona Zupo; Mariella Dono; Laura Rassenti; Hansjuerg Alder; Stefano Volinia; Chang-gong liu; Thomas Kipps; Massimo Negrini; Carlo M Croce
miR-15 and miR-16 induce apoptosis by targeting BCL2.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):13944-9.
2005: Silvia Anna Ciafrè; S Galardi; Annunziato Mangiola; Manuela Ferracin; Chang-gong liu; Giovanni Sabatino; Massimo Negrini; Giulio Maira; Carlo M Croce; Maria Giulia Farace
Extensive modulation of a set of microRNAs in primary glioblastoma.
Biochemical and biophysical research communications 2005;334(4):1351-8.
2005: Chang-gong liu; Liang Zhang; Yubao Jiang; Devjani Chatterjee; Carlo M Croce; Kay Huebner; Louise Y Y Fong
Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment.
Cancer research 2005;65(17):7790-9.
2005: Marilena V Iorio; Manuela Ferracin; Chang-gong liu; Angelo Veronese; Riccardo Spizzo; Silvia Sabbioni; Eros Magri; Massimo Pedriali; Muller Fabbri; Manuela Campiglio; Sylvie Ménard; Juan P Palazzo; Anne Rosenberg; Piero Musiani; Stefano Volinia; italo nenci; George A Calin; Patrizia Querzoli; Massimo Negrini; Carlo M Croce
MicroRNA gene expression deregulation in human breast cancer.
Cancer research 2005;65(16):7065-70.
2005: Alessandra Drusco; nicola zanesi; Claudia Roldo; Francesco Trapasso; John L Farber; Louise Y Y Fong; Carlo M Croce
Knockout mice reveal a tumor suppressor function for Testin.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10947-51.
2005: Rami I Aqeilan; Valentina Donati; Alexey Palamarchuk; Francesco Trapasso; Mohamed Kaou; yuri pekarsky; Marius Sudol; Carlo M Croce
WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function.
Cancer research 2005;65(15):6764-72.
2005: nicola zanesi; Rita Mancini; Cinzia Sevignani; Aldo Vecchione; Mohamed Kaou; Mauro Valtieri; George A Calin; yuri pekarsky; James R Gnarra; Carlo M Croce; Kay Huebner
Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.
Cancer research 2005;65(15):6576-82.
2005: Carlo M Croce; George A Calin
miRNAs, cancer, and stem cell division.
Cell 2005;122(1):6-7.
2005: Hideshi Ishii; Taeko Inageta; Koshi Mimori; Toshiyuki Saito; Hiroki Sasaki; Masaharu Isobe; Masaki Mori; Carlo M Croce; Kay Huebner; Keiya Ozawa; Yusuke Furukawa
Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(27):9655-60.
2005: Daniela Foti; Eusebio Chiefari; Monica Fedele; Rodolfo Iuliano; Leonardo Brunetti; Francesco Paonessa; Guidalberto Manfioletti; Fabrizio Barbetti; Antonio Brunetti; Carlo M Croce; Alfredo Fusco; Antonio Brunetti
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice.
Nature medicine 2005;11(7):765-73.
2005: Matthew G Guenther; Richard G Jenner; Brett Chevalier; Tatsuya Nakamura; Carlo M Croce; Eli Canaani; Richard A Young
Global and Hox-specific roles for the MLL1 methyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(24):8603-8.
2005: Alexey Palamarchuk; Alexey Efanov; Vadim Maximov; Rami I Aqeilan; Carlo M Croce; yuri pekarsky
Akt phosphorylates Tal1 oncoprotein and inhibits its repressor activity.
Cancer research 2005;65(11):4515-9.
2005: Monica Fedele; Francesca Pentimalli; Gustavo Baldassarre; Sabrina Battista; Andres J P Klein-Szanto; Lawrence Kenyon; Rosa Visone; Ivana De Martino; Andrea Ciarmiello; Claudio Arra; Giuseppe Viglietto; Carlo M Croce; Alfredo Fusco
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.
Oncogene 2005;24(21):3427-35.
2005: Preston N Garrison; Angela K Robinson; yuri pekarsky; Carlo M Croce; Larry D Barnes
Phosphorylation of the human Fhit tumor suppressor on tyrosine 114 in Escherichia coli and unexpected steady state kinetics of the phosphorylated forms.
Biochemistry 2005;44(16):6286-92.
2005: Daisuke Nonaka; Alessandra Fabbri; Luca Roz; Luigi Mariani; Andrea Vecchione; GW Moore; Luca Tavecchio; Carlo M Croce; Gabriella Sozzi
Reduced FEZ1/LZTS1 expression and outcome prediction in lung cancer.
Cancer research 2005;65(4):1207-12.
2005: Manuela Sarti; Cinzia Sevignani; George A Calin; Rami I Aqeilan; Masayoshi Shimizu; Francesca Pentimalli; Maria Cristina Picchio; Andrew Godwin; Anne Rosenberg; Alessandra Drusco; Massimo Negrini; Carlo M Croce
Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):806-13.
2004: Aldo Vecchione; Cinzia Sevignani; Enrico Giarnieri; nicola zanesi; Hideshi Ishii; Rossano Cesari; Louise Y Y Fong; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
Inactivation of the FHIT gene favors bladder cancer development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(22):7607-12.
2004: Rami I Aqeilan; Alexey Palamarchuk; Ronald J Weigel; Juan J Herrero; yuri pekarsky; Carlo M Croce
Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor.
Cancer research 2004;64(22):8256-61.
2004: Michelle Ottey; Shuang-Yin Han; Teresa Druck; B L Barnoski; Kelly A McCorkell; Carlo M Croce; Carmen Raventos-Suarez; C R Fairchild; Ya Wang; Kay Huebner
Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant.
British journal of cancer 2004;91(9):1669-77.
2004: Francesco Trapasso; Sai Yendamuri; Kristoffel R Dumon; Rodolfo Iuliano; Rossano Cesari; Byron Feig; Robin Seto; Luisa Infante; Hideshi Ishii; Aldo Vecchione; Matthew J During; Carlo M Croce; Alfredo Fusco
Restoration of receptor-type protein tyrosine phosphatase eta function inhibits human pancreatic carcinoma cell growth in vitro and in vivo.
Carcinogenesis 2004;25(11):2107-14.
2004: Hideshi Ishii; Aldo Vecchione; Yusuke Furukawa; Carlo M Croce; Kay Huebner; Louise Y Y Fong
Differentially expressed genes execute zinc-induced apoptosis in precancerous esophageal epithelium of zinc-deficient rats.
Oncogene 2004;23(49):8040-8.
2004: Aldo Vecchione; Tommaso Prayer Galetti; Marina Gardiman; Hideshi Ishii; Enrico Giarnieri; Francesco Pagano; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
Collecting duct carcinoma of the kidney: an immunohistochemical study of 11 cases.
BMC urology 2004;4():11.
2004: Francesco Trapasso; Manuela Sarti; Rossano Cesari; Sai Yendamuri; Kristoffel R Dumon; Rami I Aqeilan; Francesca Pentimalli; Luisa Infante; Hansjuerg Alder; Nobutsugu Abe; Takashi Watanabe; Giuseppe Viglietto; Carlo M Croce; Alfredo Fusco
Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models.
Cancer gene therapy 2004;11(9):633-41.
2004: George A Calin; Chang-gong liu; Cinzia Sevignani; Manuela Ferracin; Nadia Felli; Calin Dan Dumitru; Masayoshi Shimizu; Amelia Cimmino; Simona Zupo; Mariella Dono; Marie L Dell'Aquila; Hansjuerg Alder; Laura Rassenti; Thomas Kipps; Florencia Bullrich; Massimo Negrini; Carlo M Croce
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11755-60.
2004: yuri pekarsky; nicola zanesi; Rami I Aqeilan; Carlo M Croce
Tcl1 as a model for lymphomagenesis.
Hematology/oncology clinics of North America 2004;18(4):863-79, ix.
2004: Chang-gong liu; George A Calin; Brian Meloon; Nir Gamliel; Cinzia Sevignani; Manuela Ferracin; Calin Dan Dumitru; Masayoshi Shimizu; Simona Zupo; Mariella Dono; Hansjuerg Alder; Florencia Bullrich; Massimo Negrini; Carlo M Croce
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9740-4.
2004: Rami I Aqeilan; Tamotsu Kuroki; yuri pekarsky; Omar Albagha; Francesco Trapasso; Raffaele Baffa; Kay Huebner; Pamela Edmonds; Carlo M Croce
Loss of WWOX expression in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3053-8.
2004: Eric S Martin; Carlo M Croce; David D Biggs; S Eric Martin
BRCA1 IVS2-2delA: a deleterious mutation in a family of Asian descent.
Cancer genetics and cytogenetics 2004;150(2):173-5.
2004: Tamotsu Kuroki; Sai Yendamuri; Francesco Trapasso; Ayumi Matsuyama; Rami I Aqeilan; Hansjuerg Alder; Shashi Rattan; Rossano Cesari; Maria L Nolli; Noel N Williams; Masaki Mori; Takashi Kanematsu; Carlo M Croce
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2459-65.
2004: Rami I Aqeilan; yuri pekarsky; Juan J Herrero; Alexey Palamarchuk; Jean Letofsky; Teresa Druck; Francesco Trapasso; Shuang-Yin Han; Gerry Melino; Kay Huebner; Carlo M Croce
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4401-6.
2004: yuri pekarsky; Preston N Garrison; Alexey Palamarchuk; nicola zanesi; Rami I Aqeilan; Kay Huebner; Larry D Barnes; Carlo M Croce
Fhit is a physiological target of the protein kinase Src.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(11):3775-9.
2004: George A Calin; Cinzia Sevignani; Calin Dan Dumitru; Terry Hyslop; Evan Noch; Sai Yendamuri; Masayoshi Shimizu; Shashi Rattan; Florencia Bullrich; Massimo Negrini; Carlo M Croce
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):2999-3004.
2004: Hideshi Ishii; Andrea Vecchione; Louise Y Y Fong; nicola zanesi; Francesco Trapasso; Yusuke Furukawa; Raffaele Baffa; Kay Huebner; Carlo M Croce
Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses.
Current gene therapy 2004;4(1):53-63.
2004: Eli Canaani; Tatsuya Nakamura; Tanya Rozovskaia; Sheryl T Smith; T Mori; Carlo M Croce; Alexander Mazo
ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia.
British journal of cancer 2004;90(4):756-60.
2004: Ayumi Matsuyama; Carlo M Croce; Kay Huebner
Common fragile genes.
European journal of histochemistry : EJH 2004;48(1):29-36.
2004: Svetlana Petruk; Yurii Sedkov; Sheryl T Smith; Wladyslaw Krajewski; Tatsuya Nakamura; Eli Canaani; Carlo M Croce; Alexander Mazo
Purification and biochemical properties of the Drosophila TAC1 complex.
Methods in enzymology 2004;377():255-66.
2003: Ayumi Matsuyama; Takeshi Shiraishi; Francesco Trapasso; Tamotsu Kuroki; Hansjuerg Alder; Masaki Mori; Kay Huebner; Carlo M Croce
Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14988-93.
2003: Carlo M Croce
A passion for discovery.
Cancer biology & therapy 2003;2(6):719-20.
2003: Hideshi Ishii; Andrea Vecchione; Yutaka Furukawa; Krittaya Sutheesophon; Shuang-Yin Han; Teresa Druck; Tamotsu Kuroki; Francesco Trapasso; Miki Nishimura; Yasushi Saito; Keiya Ozawa; Carlo M Croce; Kay Huebner; Yusuke Furukawa
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
Molecular cancer research : MCR 2003;1(13):940-7.
2003: Eric S Martin; Rossano Cesari; Francesca Pentimalli; Kristine Yoder; Richard Fishel; Andrew L Himelstein; S Eric Martin; Andrew K Godwin; Massimo Negrini; Carlo M Croce
The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11517-22.
2003: Hideshi Ishii; nicola zanesi; Aldo Vecchione; Francesco Trapasso; Sai Yendamuri; Manuela Sarti; Raffaele Baffa; Matthew J During; Kay Huebner; Louise Y Y Fong; Carlo M Croce
Regression of upper gastric cancer in mice by FHIT gene delivery.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1768-70.
2003: Nicoletta Ferrari; Giulio L Palmisano; Laura Paleari; Giuseppe Basso; Manuela Mangioni; Vincenzo Fidanza; Adriana Albini; Carlo M Croce; Giovanni Levi; Claudio Brigati
DLX genes as targets of ALL-1: DLX 2,3,4 down-regulation in t(4;11) acute lymphoblastic leukemias.
Journal of leukocyte biology 2003;74(2):302-5.
2003: Sabrina Battista; Francesca Pentimalli; Gustavo Baldassarre; Monica Fedele; Vincenzo Fidanza; Carlo M Croce; Alfredo Fusco
Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(11):1496-8.
2003: Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Masaki Mori; Carlo M Croce
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
Cancer research 2003;63(13):3724-8.
2003: Tanya Rozovskaia; O Ravid-Amir; Sergei Tillib; G Getz; Elena Feinstein; Himanshu Agrawal; Arnon Nagler; E F Rappaport; Irina Issaeva; Y Matsuo; U R Kees; T Lapidot; F Lo Coco; R Foa; Alexander Mazo; Tatsuya Nakamura; Carlo M Croce; G Cimino; Eytan Domany; Eli Canaani
Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7853-8.
2003: Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Noel N Williams; Larry R Kaiser; Carlo M Croce
Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer.
Cancer research 2003;63(12):3352-5.
2003: Sanjay Thakur; Tatsuya Nakamura; George Calin; Andrea Russo; Joseph F Tamburrino; Masayoshi Shimizu; Gustavo Baldassarre; Sabrina Battista; Alfredo Fusco; Richard Wassell; Garrett C DuBois; Hansjuerg Alder; Carlo M Croce
Regulation of BRCA1 transcription by specific single-stranded DNA binding factors.
Molecular and cellular biology 2003;23(11):3774-87.
2003: Kay Huebner; Carlo M Croce
Cancer and the FRA3B/FHIT fragile locus: it's a HIT.
British journal of cancer 2003;88(10):1501-6.
2003: Rossano Cesari; Eric S Martin; George A Calin; Francesca Pentimalli; Roberta Bichi; Holly McAdams; Francesco Trapasso; Alessandra Drusco; Masayoshi Shimizu; Valeria Masciullo; Giuseppina D'Andrilli; Giovanni Scambia; Maria Cristina Picchio; Hansjuerg Alder; Andrew K Godwin; Carlo M Croce
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5956-61.
2003: Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Masaki Mori; Carlo M Croce
Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(4):1441-5.
2003: Gustavo Baldassarre; Sabrina Battista; Barbara Belletti; Sanjay Thakur; Francesca Pentimalli; Francesco Trapasso; Monica Fedele; Giovanna Maria Pierantoni; Carlo M Croce; Alfredo Fusco
Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma.
Molecular and cellular biology 2003;23(7):2225-38.
2003: Cinzia Sevignani; George A Calin; Rossano Cesari; Manuela Sarti; Hideshi Ishii; Sai Yendamuri; Aldo Vecchione; Francesco Trapasso; Carlo M Croce
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines.
Cancer research 2003;63(6):1183-7.
2003: Francesco Trapasso; Agnieszka Krakowiak; Rossano Cesari; Jeffrey Arkles; Sai Yendamuri; Hideshi Ishii; Aldo Vecchione; Tamotsu Kuroki; Pawel Bieganowski; Helen C Pace; Kay Huebner; Carlo M Croce; Charles Brenner
Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1592-7.
2003: Sai Yendamuri; Tamotsu Kuroki; Francesco Trapasso; Adam C Henry; Kristoffel R Dumon; Kay Huebner; Noel N Williams; Larry R Kaiser; Carlo M Croce
WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer.
Cancer research 2003;63(4):878-81.
2003: yuri pekarsky; Cora Hallas; Carlo M Croce
Targeting mature T cell leukemia: new understanding of molecular pathways.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 2003;3(1):31-6.
2003: Louise Y Y Fong; Hideshi Ishii; Vu T Nguyen; Aldo Vecchione; John L Farber; Carlo M Croce; Kay Huebner
p53 deficiency accelerates induction and progression of esophageal and forestomach tumors in zinc-deficient mice.
Cancer research 2003;63(1):186-95.
2002: yuri pekarsky; nicola zanesi; Alexey Palamarchuk; Kay Huebner; Carlo M Croce
FHIT: from gene discovery to cancer treatment and prevention.
The lancet oncology 2002;3(12):748-54.
2002: George A Calin; Calin Dan Dumitru; Masayoshi Shimizu; Roberta Bichi; Simona Zupo; Evan Noch; Hansjuerg Aldler; Shashi Rattan; Michael Keating; Kanti Rai; Laura Rassenti; Thomas Kipps; Massimo Negrini; Florencia Bullrich; Carlo M Croce
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15524-9.
2002: Tatsuya Nakamura; Toshiki Mori; Shinichiro Tada; Wladyslaw Krajewski; Tanya Rozovskaia; Richard Wassell; Garrett C DuBois; Alexander Mazo; Carlo M Croce; Eli Canaani
ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.
Molecular cell 2002;10(5):1119-28.
2002: Gianluigi Condorelli; Carmine Morisco; Michael V G Latronico; Pier Paolo Claudio; Paul Dent; Philip Tsichlis; Gerolama Condorelli; Giacomo Frati; Alessandra Drusco; Carlo M Croce; Claudio Napoli
TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1732-7.
2002: Gianluigi Condorelli; Alessandra Drusco; Giorgio Stassi; Alfonso Bellacosa; Roberta Roncarati; guido iaccarino; Matteo A Russo; Yusu Gu; Nancy Dalton; Clarence Chung; Michael V G Latronico; Claudio Napoli; Junichi Sadoshima; Carlo M Croce; John Ross
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12333-8.
2002: Shin Sasaki; Tatsuya Nakamura; Hirofumi Arakawa; Masaki Mori; Toshiaki Watanabe; Hirokazu Nagawa; Carlo M Croce
Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer.
Oncogene 2002;21(32):5024-30.
2002: John M Petock; Ivan Y Torshin; Yuan-Fang Wang; Garrett C Du Bois; Carlo M Croce; Robert W Harrison; Irene T Weber
Crystal structures of Tcl1 family oncoproteins and their conserved surface features.
TheScientificWorldJournal 2002;2():1876-84.
2002: Roberta Bichi; Susan A Shinton; Eric S Martin; Anatoliy Koval; George A Calin; Rossano Cesari; Giandomenico Russo; Richard R Hardy; Carlo M Croce
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6955-60.
2002: Monica Fedele; Sabrina Battista; Lawrence Kenyon; Gustavo Baldassarre; Vincenzo Fidanza; Andres J P Klein-Szanto; A F Parlow; Rosa Visone; Giovanna Maria Pierantoni; Eric K Outwater; Massimo Santoro; Carlo M Croce; Alfredo Fusco
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.
Oncogene 2002;21(20):3190-8.
2002: yuri pekarsky; Alexey Palamarchuk; Kay Huebner; Carlo M Croce
FHIT as tumor suppressor: mechanisms and therapeutic opportunities.
Cancer biology & therapy 2002;1(3):232-6.
2002: Palma Finelli; Giovanna Maria Pierantoni; Daniela Giardino; Marco Losa; Ornella Rodeschini; Monica Fedele; Emanuele Valtorta; pietro mortini; Carlo M Croce; Lidia Larizza; Alfredo Fusco
The High Mobility Group A2 gene is amplified and overexpressed in human prolactinomas.
Cancer research 2002;62(8):2398-405.
2002: Tamotsu Kuroki; Francesco Trapasso; Takeshi Shiraishi; Hansjuerg Alder; Koshi Mimori; Masaki Mori; Carlo M Croce
Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma.
Cancer research 2002;62(8):2258-60.
2002: Aldo Vecchione; Hideshi Ishii; Gustavo Baldassarre; Pierfrancesco Bassi; Francesco Trapasso; Hansjuerg Alder; Francesco Pagano; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
FEZ1/LZTS1 is down-regulated in high-grade bladder cancer, and its restoration suppresses tumorigenicity in transitional cell carcinoma cells.
The American journal of pathology 2002;160(4):1345-52.
2002: Luca Roz; Marcella Gramegna; Hideshi Ishii; Carlo M Croce; Gabriella Sozzi
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3615-20.
2001: Kay Huebner; Carlo M Croce
FRA3B and other common fragile sites: the weakest links.
Nature reviews. Cancer 2001;1(3):214-21.
2001: Hideshi Ishii; Kristoffel R Dumon; Aldo Vecchione; Louise Y Y Fong; Raffaele Baffa; Kay Huebner; Carlo M Croce
Potential cancer therapy with the fragile histidine triad gene: review of the preclinical studies.
JAMA : the journal of the American Medical Association 2001;286(19):2441-9.
2001: yuri pekarsky; Cora Hallas; Carlo M Croce
Molecular basis of mature T-cell leukemia.
JAMA : the journal of the American Medical Association 2001;286(18):2308-14.
2001: Svetlana Petruk; Yurii Sedkov; S Smith; Sergei Tillib; V Kraevski; Tatsuya Nakamura; Eli Canaani; Carlo M Croce; Alexander Mazo
Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene.
Science (New York, N.Y.) 2001;294(5545):1331-4.
2001: John M Petock; Ivan Y Torshin; Yuan-Fang Wang; Garrett C Du Bois; Carlo M Croce; Robert W Harrison; Irene T Weber
Structure of murine Tcl1 at 2.5 A resolution and implications for the TCL oncogene family.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 11):1545-51.
2001: Monica Fedele; Sabrina Battista; Guidalberto Manfioletti; Carlo M Croce; Vincenzo Giancotti; Alfredo Fusco
Role of the high mobility group A proteins in human lipomas.
Carcinogenesis 2001;22(10):1583-91.
2001: Maher Albitar; Taghi Manshouri; Christy Gidel; Carlo M Croce; Steven M Kornblau; Sherry Pierce; Hagop M Kantarjian
Clinical significance of fragile histidine triad gene expression in adult acute lymphoblastic leukemia.
Leukemia research 2001;25(10):859-64.
2001: Carlo M Croce
How can we prevent cancer?
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):10986-8.
2001: Yoshiki Murakumo; Y Ogura; Hideshi Ishii; Shin-ichiro Numata; Masatoshi Ichihara; Carlo M Croce; Richard Fishel; Masahide Takahashi
Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7.
The Journal of biological chemistry 2001;276(38):35644-51.
2001: Florencia Bullrich; H Fujii; George A Calin; H Mabuchi; Massimo Negrini; yuri pekarsky; Laura Rassenti; Hansjuerg Alder; J C Reed; M J Keating; Thomas Kipps; Carlo M Croce
Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene.
Cancer research 2001;61(18):6640-8.
2001: yuri pekarsky; Cora Hallas; Carlo M Croce
The role of TCL1 in human T-cell leukemia.
Oncogene 2001;20(40):5638-43.
2001: nicola zanesi; Carlo M Croce
Fragile histidine triad gene and skin cancer.
European journal of dermatology : EJD 2001;11(5):401-4.
2001: nicola zanesi; Vincenzo Fidanza; Louise Y Y Fong; Rita Mancini; Teresa Druck; Mauro Valtieri; T Rüdiger; Peter McCue; Carlo M Croce; Kay Huebner
The tumor spectrum in FHIT-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10250-5.
2001: Hideshi Ishii; Aldo Vecchione; Yoshiki Murakumo; Gustavo Baldassarre; Shin-ichiro Numata; Francesco Trapasso; Hansjuerg Alder; Raffaele Baffa; Carlo M Croce
FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10374-9.
2001: Gianluigi Condorelli; Roberta Roncarati; J Ross; A Pisani; Giorgio Stassi; Matilde Todaro; Steven D. Trocha; Alessandra Drusco; Yusu Gu; Matteo A Russo; Giacomo Frati; Steven P Jones; David J Lefer; Claudio Napoli; Carlo M Croce
Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9977-82.
2001: Gustavo Baldassarre; Monica Fedele; Sabrina Battista; Aldo Vecchione; Andres J P Klein-Szanto; Massimo Santoro; Thomas Waldmann; N Azimi; Carlo M Croce; Alfredo Fusco
Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7970-5.
2001: Kristoffel R Dumon; Hideshi Ishii; Aldo Vecchione; Francesco Trapasso; Gustavo Baldassarre; F Chakrani; Teresa Druck; E F Rosato; Noel N Williams; Raffaele Baffa; Matthew J During; Kay Huebner; Carlo M Croce
Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer.
Cancer research 2001;61(12):4827-36.
2001: Aldo Vecchione; Hideshi Ishii; Yih-Horng Shiao; Francesco Trapasso; M Rugge; J F Tamburrino; Yoshiki Murakumo; Hansjuerg Alder; Carlo M Croce; Raffaele Baffa
Fez1/lzts1 alterations in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(6):1546-52.
2001: T Shiraishi; Teresa Druck; Koshi Mimori; J Flomenberg; L Berk; Hansjuerg Alder; W Miller; Kay Huebner; Carlo M Croce
Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5722-7.
2001: Aldo Vecchione; nicola zanesi; Giorgio Trombetta; D French; Paolo Visca; Tiziana Pisani; Claudio Botti; A Vecchione; Carlo M Croce; Rita Mancini
Cervical dysplasia, ploidy, and human papillomavirus status correlate with loss of Fhit expression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1306-12.
2001: H Mabuchi; H Fujii; George A Calin; Hansjuerg Alder; Massimo Negrini; Laura Rassenti; Thomas Kipps; Florencia Bullrich; Carlo M Croce
Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia.
Cancer research 2001;61(7):2870-7.
2001: Rosa Marina Melillo; Giovanna Maria Pierantoni; Stefania Scala; Sabrina Battista; Monica Fedele; A Stella; MC De Biasio; Gennaro Chiappetta; Vincenzo Fidanza; G Condorelli; Massimo Santoro; Carlo M Croce; Giuseppe Viglietto; Alfredo Fusco
Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation.
Molecular and cellular biology 2001;21(7):2485-95.
2001: yuri pekarsky; Cora Hallas; Alexey Palamarchuk; Anatoliy Koval; Florencia Bullrich; Y Hirata; Roberta Bichi; Jean Letofsky; Carlo M Croce
Akt phosphorylates and regulates the orphan nuclear receptor Nur77.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3690-4.
2001: Kristoffel R Dumon; Hideshi Ishii; Louise Y Y Fong; nicola zanesi; Vincenzo Fidanza; Rita Mancini; Aldo Vecchione; Raffaele Baffa; Francesco Trapasso; Matthew J During; Kay Huebner; Carlo M Croce
FHIT gene therapy prevents tumor development in Fhit-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3346-51.
2001: Tanya Rozovskaia; Elena Feinstein; Orna Mor; R Foa; Janna Blechman; Tatsuya Nakamura; Carlo M Croce; G Cimino; Eli Canaani
Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality.
Oncogene 2001;20(7):874-8.
2001: Hideshi Ishii; Kristoffel R Dumon; Aldo Vecchione; Francesco Trapasso; Koshi Mimori; Hansjuerg Alder; Masaki Mori; Gabriella Sozzi; Raffaele Baffa; Kay Huebner; Carlo M Croce
Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells.
Cancer research 2001;61(4):1578-84.
2000: F Stefania Falvella; Elena Menegola; Erminio Giavini; Michelle Ottey; Vincenzo Fidanza; Carlo M Croce; Kay Huebner; Tommaso A Dragani
Expression of Fhit protein during mouse development.
The Anatomical record 2000;260(2):208-11.
2000: C Tatarelli; A Linnenbach; Koshi Mimori; Carlo M Croce
Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2.
Genomics 2000;68(1):1-12.
2000: T Mastrangelo; Piergiorgio Modena; S Tornielli; F Bullrich; Maria Adele Testi; Alessandra Mezzelani; Paolo Radice; A Azzarelli; Silvana Pilotti; Carlo M Croce; Marco A Pierotti; Gabriella Sozzi
A novel zinc finger gene is fused to EWS in small round cell tumor.
Oncogene 2000;19(33):3799-804.
2000: Helen C Pace; Santosh C Hodawadekar; A Draganescu; J Huang; Pawel Bieganowski; yuri pekarsky; Carlo M Croce; Charles Brenner
Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers.
Current biology : CB 2000;10(15):907-17.
2000: Luigi Vitelli; Gianluigi Condorelli; Valentina Lulli; T Hoang; L Luchetti; Carlo M Croce; Cesare Peschle
A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblasts.
Molecular and cellular biology 2000;20(14):5330-42.
2000: Tatsuya Nakamura; Janna Blechman; S Tada; Tanya Rozovskaia; T Itoyama; Florencia Bullrich; Alexander Mazo; Carlo M Croce; B Geiger; Eli Canaani
huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7284-9.
2000: J L Wang; D Liu; Z J Zhang; S Shan; X Han; S M Srinivasula; Carlo M Croce; Emad S Alnemri; Ziwei Huang
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7124-9.
2000: Christine Schwienbacher; Laura Gramantieri; Rosaria A M Scelfo; Angelo Veronese; George A Calin; Luigi Bolondi; Carlo M Croce; Giuseppe Barbanti-Brodano; Massimo Negrini
Gain of imprinting at chromosome 11p15: A pathogenetic mechanism identified in human hepatocarcinomas.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5445-9.
2000: Louise Y Y Fong; Vincenzo Fidanza; nicola zanesi; L F Lock; Linda D Siracusa; Rita Mancini; Z Siprashvili; Michelle Ottey; S Eric Martin; Teresa Druck; Peter McCue; Carlo M Croce; Kay Huebner
Muir-Torre-like syndrome in Fhit-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4742-7.
2000: Maria Grazia Narducci; Edoardo Pescarmona; Cristina Lazzeri; S Signoretti; AM Lavinia; Daniele Remotti; Enrico Scala; Carlo Davide Baroni; Antonella Stoppacciaro; Carlo M Croce; Giandomenico Russo
Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues.
Cancer research 2000;60(8):2095-100.
2000: Raffaele Baffa; R Santoro; F Bullrich; B Mandes; Hideshi Ishii; Carlo M Croce
Definition and refinement of chromosome 8p regions of loss of heterozygosity in gastric cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1372-7.
2000: Garrett C Du Bois; SP Song; I Kulikovskaya; Jay L Rothstein; Markus Germann; Carlo M Croce
Purification and characterization of recombinant forms of murine Tcl1 proteins.
Protein expression and purification 2000;18(3):277-85.
2000: yuri pekarsky; Anatoliy Koval; Cora Hallas; Roberta Bichi; M Tresini; SE Malstrom; Giandomenico Russo; Philip Tsichlis; Carlo M Croce
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3028-33.
2000: J L Wang; Z J Zhang; Swati Choksi; S Shan; Z Lu; Carlo M Croce; Emad S Alnemri; Robert Korngold; Ziwei Huang
Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells.
Cancer research 2000;60(6):1498-502.
2000: George A Calin; Maria Grazia di Iasio; E Caprini; I Vorechovsky; P G Natali; Gabriella Sozzi; Carlo M Croce; Giuseppe Barbanti-Brodano; Giandomenico Russo; Massimo Negrini
Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms.
Oncogene 2000;19(9):1191-5.
2000: Yoshiki Murakumo; T Roth; Hideshi Ishii; D Rasio; Shin-ichiro Numata; Carlo M Croce; Richard Fishel
A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2.
The Journal of biological chemistry 2000;275(6):4391-7.
2000: Raffaele Baffa; Leonard G Gomella; Aldo Vecchione; Pierfrancesco Bassi; Koshi Mimori; John Sedor; C M Calviello; Marina Gardiman; Corrado Minimo; Stephen E Strup; Peter McCue; Albert J Kovatich; Francesco Pagano; Kay Huebner; Carlo M Croce
Loss of FHIT expression in transitional cell carcinoma of the urinary bladder.
The American journal of pathology 2000;156(2):419-24.
2000: Tanya Rozovskaia; Orit Rozenblatt-Rosen; Yurii Sedkov; D Burakov; T Yano; Tatsuya Nakamura; S Petruck; Levana Ben-Simchon; Carlo M Croce; Alexander Mazo; Eli Canaani
Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteins.
Oncogene 2000;19(3):351-7.
1999: Cora Hallas; yuri pekarsky; T Itoyama; JM Varnum; Roberta Bichi; Jay L Rothstein; Carlo M Croce
Genomic analysis of human and mouse TCL1 loci reveals a complex of tightly clustered genes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14418-23.
1999: Sabrina Battista; Vincenzo Fidanza; Monica Fedele; Andres J P Klein-Szanto; Eric K Outwater; H Brunner; Massimo Santoro; Carlo M Croce; Alfredo Fusco
The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis.
Cancer research 1999;59(19):4793-7.
1999: Cora Hallas; M Albitar; Jean Letofsky; M J Keating; Kay Huebner; Carlo M Croce
Loss of FHIT expression in acute lymphoblastic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2409-14.
1999: Tanya Rozovskaia; Sergei Tillib; S Smith; Yurii Sedkov; Orit Rozenblatt-Rosen; Svetlana Petruk; T Yano; Tatsuya Nakamura; Levana Ben-Simchon; J Gildea; Carlo M Croce; A Shearn; Eli Canaani; Alexander Mazo
Trithorax and ASH1 interact directly and associate with the trithorax group-responsive bxd region of the Ultrabithorax promoter.
Molecular and cellular biology 1999;19(9):6441-7.
1999: Manuela Campiglio; yuri pekarsky; S Menard; Elda Tagliabue; S Pilotti; Carlo M Croce
FHIT loss of function in human primary breast cancer correlates with advanced stage of the disease.
Cancer research 1999;59(16):3866-9.
1999: Shin-ichiro Numata; Pier Paolo Claudio; C Dean; Antonio Giordano; Carlo M Croce
Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product.
Cancer research 1999;59(15):3741-7.
1999: L Sard; Paola Accornero; S Tornielli; Domenico Delia; G Bunone; Manuela Campiglio; Mario P Colombo; Marcella Gramegna; Carlo M Croce; Marco A Pierotti; Gabriella Sozzi
The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8489-92.
1999: Antonio Cuneo; Renato Bigoni; Gian Matteo Rigolin; Maria Grazia Roberti; Antonella Bardi; Diana Campioni; Claudia Minotto; Paola Agostini; Raffaella Milani; Florencia Bullrich; Massimo Negrini; Carlo M Croce; Gianluigi Castoldi
13q14 deletion in non-Hodgkin's lymphoma: correlation with clinicopathologic features.
Haematologica 1999;84(7):589-93.
1999: Koshi Mimori; Teresa Druck; H Inoue; Hansjuerg Alder; L Berk; Masaki Mori; Kay Huebner; Carlo M Croce
Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7456-61.
1999: Hideshi Ishii; Raffaele Baffa; Shin-ichiro Numata; Yoshiki Murakumo; Shashi Rattan; H Inoue; Masaki Mori; Vincenzo Fidanza; Hansjuerg Alder; Carlo M Croce
The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3928-33.
1999: S Thakur; Carlo M Croce
Positive regulation of the BRCA1 promoter.
The Journal of biological chemistry 1999;274(13):8837-43.
1999: yuri pekarsky; Cora Hallas; M Isobe; Giandomenico Russo; Carlo M Croce
Abnormalities at 14q32.1 in T cell malignancies involve two oncogenes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2949-51.
1999: T Bocker; Alan Barusevicius; Timothy Snowden; D Rasio; S Guerrette; D Robbins; C Schmidt; J Burczak; Carlo M Croce; T Copeland; Albert J Kovatich; Richard Fishel
hMSH5: a human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis.
Cancer research 1999;59(4):816-22.
1999: Antonio Cuneo; Renato Bigoni; Gian Matteo Rigolin; Maria Grazia Roberti; Antonella Bardi; N Piva; Raffaella Milani; Florencia Bullrich; Maria L Veronese; Carlo M Croce; F Birg; H Döhner; Anne Hagemeijer; Gianluigi Castoldi
Cytogenetic profile of lymphoma of follicle mantle lineage: correlation with clinicobiologic features.
Blood 1999;93(4):1372-80.
1999: Gabriella Sozzi; Maria Adele Testi; Carlo M Croce
Advances in cancer cytogenetics.
Journal of cellular biochemistry 1999;Suppl 32-33():173-82.
1999: Silvia Sabbioni; Angelo Veronese; Maurizio Trubia; Roberto Taramelli; Giuseppe Barbanti-Brodano; Carlo M Croce; Massimo Negrini
Exon structure and promoter identification of STIM1 (alias GOK), a human gene causing growth arrest of the human tumor cell lines G401 and RD.
Cytogenetics and cell genetics 1999;86(3-4):214-8.
1999: Florencia Bullrich; D Rasio; Shinichi Kitada; P Starostik; Thomas Kipps; M Keating; M Albitar; J C Reed; Carlo M Croce
ATM mutations in B-cell chronic lymphocytic leukemia.
Cancer research 1999;59(1):24-7.
1998: Gabriella Sozzi; Ugo Pastorino; L Moiraghi; Elda Tagliabue; Francesco Pezzella; Cristina Ghirelli; S Tornielli; L Sard; Kay Huebner; Marco A Pierotti; Carlo M Croce; Silvana Pilotti
Loss of FHIT function in lung cancer and preinvasive bronchial lesions.
Cancer research 1998;58(22):5032-7.
1998: Raffaele Baffa; Maria L Veronese; R Santoro; B Mandes; Juan P Palazzo; M Rugge; E Santoro; Carlo M Croce; Kay Huebner
Loss of FHIT expression in gastric carcinoma.
Cancer research 1998;58(20):4708-14.
1998: C Monaco; M Helmer Citterich; E Caprini; I Vorechovsky; Giandomenico Russo; Carlo M Croce; Giuseppe Barbanti-Brodano; Massimo Negrini
Molecular cloning and characterization of ZNF202: a new gene at 11q23.3 encoding testis-specific zinc finger proteins.
Genomics 1998;52(3):358-62.
1998: Loris Zamai; Marco Vitale; IM Bennett; Carlo M Croce; Bice Perussia
A novel surface marker (B203.13) of human haemopoietic progenitors, preferentially expressed along the B and myeloid lineages.
British journal of haematology 1998;102(4):965-75.
1998: yuri pekarsky; Teresa Druck; M G Cotticelli; M Ohta; J Shou; Jeannine M Mendrola; JC Montgomery; Arthur M Buchberg; Linda D Siracusa; Giacomo Manenti; L Y Fong; Tommaso A Dragani; Carlo M Croce; Kay Huebner
The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells.
Cancer research 1998;58(15):3401-8.
1998: yuri pekarsky; Manuela Campiglio; Z Siprashvili; Teresa Druck; Yurii Sedkov; Sergei Tillib; A Draganescu; P Wermuth; J H Rothman; Kay Huebner; Arthur M Buchberg; Alexander Mazo; Charles Brenner; Carlo M Croce
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8744-9.
1998: Helen C Pace; Preston N Garrison; Angela K Robinson; Larry D Barnes; A Draganescu; A Rösler; G Michael Blackburn; Z Siprashvili; Carlo M Croce; Kay Huebner; Charles Brenner
Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5484-9.
1998: H Arakawa; Tatsuya Nakamura; A B Zhadanov; Vincenzo Fidanza; T Yano; Florencia Bullrich; M Shimizu; Janna Blechman; Alexander Mazo; Eli Canaani; Carlo M Croce
Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4573-8.
1998: Orit Rozenblatt-Rosen; Tanya Rozovskaia; D Burakov; Yurii Sedkov; Sergei Tillib; Janna Blechman; Tatsuya Nakamura; Carlo M Croce; Alexander Mazo; Eli Canaani
The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4152-7.
1998: L Virgilio; Cristina Lazzeri; Roberta Bichi; Ken-ichi Nibu; Maria Grazia Narducci; Giandomenico Russo; Jay L Rothstein; Carlo M Croce
Deregulated expression of TCL1 causes T cell leukemia in mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3885-9.
1998: Christine Schwienbacher; Silvia Sabbioni; M Campi; Angelo Veronese; G Bernardi; A Menegatti; I Hatada; T Mukai; H Ohashi; Giuseppe Barbanti-Brodano; Carlo M Croce; Massimo Negrini
Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3873-8.
1998: ZQ Fu; Garrett C Du Bois; SP Song; I Kulikovskaya; L Virgilio; Jay L Rothstein; Carlo M Croce; Irene T Weber; Robert W Harrison
Crystal structure of MTCP-1: implications for role of TCL-1 and MTCP-1 in T cell malignancies.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3413-8.
1998: Garrett C Du Bois; SP Song; I Kulikovskaya; L Virgilio; JM Varnum; Markus Germann; Carlo M Croce
Purification and characterization of recombinant forms of TCL-1 and MTCP-1 proteins.
Protein expression and purification 1998;12(2):215-25.
1998: Kay Huebner; Teresa Druck; Z Siprashvili; Carlo M Croce; Albert J Kovatich; Peter McCue
The role of deletions at the FRA3B/FHIT locus in carcinogenesis.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;154():200-15.
1998: Kay Huebner; Preston N Garrison; Larry D Barnes; Carlo M Croce
The role of the FHIT/FRA3B locus in cancer.
Annual review of genetics 1998;32():7-31.
1998: Cristina Morelli; Andrew Mungall; Massimo Negrini; Giuseppe Barbanti-Brodano; Carlo M Croce
Alternative splicing, genomic structure, and fine chromosome localization of REV3L.
Cytogenetics and cell genetics 1998;83(1-2):18-20.
1998: Gabriella Sozzi; Kay Huebner; Carlo M Croce
FHIT in human cancer.
Advances in cancer research 1998;74():141-66.
1997: H Inoue; Hideshi Ishii; Hansjuerg Alder; E Snyder; Teresa Druck; Kay Huebner; Carlo M Croce
Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14584-9.
1997: Maria Grazia Narducci; Antonella Stoppacciaro; K Imada; T Uchiyama; L Virgilio; Cristina Lazzeri; Carlo M Croce; Giandomenico Russo
TCL1 is overexpressed in patients affected by adult T-cell leukemias.
Cancer research 1997;57(24):5452-6.
1997: Z Siprashvili; Gabriella Sozzi; Larry D Barnes; Peter McCue; Angela K Robinson; V Eryomin; L Sard; Elda Tagliabue; Angela Greco; L Fusetti; Gary K Schwartz; Marco A Pierotti; Carlo M Croce; Kay Huebner
Replacement of Fhit in cancer cells suppresses tumorigenicity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13771-6.
1997: Charles Brenner; Helen C Pace; Preston N Garrison; Angela K Robinson; A Rosler; X H Liu; G Michael Blackburn; Carlo M Croce; Kay Huebner; Larry D Barnes
Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein.
Protein engineering 1997;10(12):1461-3.
1997: C Monaco; Massimo Negrini; Gabriella Sozzi; Maria L Veronese; I Vorechovsky; Andrew K Godwin; Carlo M Croce
Molecular cloning and characterization of LOH11CR2A, a new gene within a refined minimal region of LOH at 11q23.
Genomics 1997;46(2):217-22.
1997: Gabriella Sozzi; S Tornielli; Elda Tagliabue; L Sard; Francesco Pezzella; Ugo Pastorino; F Minoletti; Silvana Pilotti; Cathy Ratcliffe; Maria L Veronese; Peter Goldstraw; Kay Huebner; Carlo M Croce; Marco A Pierotti
Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities.
Cancer research 1997;57(23):5207-12.
1997: Renato Bigoni; Antonio Cuneo; Maria Grazia Roberti; Antonella Bardi; Gian Matteo Rigolin; N Piva; Gian L Scapoli; Romedio Spanedda; Massimo Negrini; Florencia Bullrich; Maria L Veronese; Carlo M Croce; Gianluigi Castoldi
Chromosome aberrations in atypical chronic lymphocytic leukemia: a cytogenetic and interphase cytogenetic study.
Leukemia 1997;11(11):1933-40.
1997: Silvia Sabbioni; Giuseppe Barbanti-Brodano; Carlo M Croce; Massimo Negrini
GOK: a gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development.
Cancer research 1997;57(20):4493-7.
1997: Maria Grazia Narducci; L Virgilio; Julie B Engiles; Arthur M Buchberg; L Billips; A Facchiano; Carlo M Croce; Giandomenico Russo; Jay L Rothstein
The murine Tcl1 oncogene: embryonic and lymphoid cell expression.
Oncogene 1997;15(8):919-26.
1997: R Prasad; A B Zhadanov; Yurii Sedkov; Florencia Bullrich; Teresa Druck; R Rallapalli; T Yano; Hansjuerg Alder; Carlo M Croce; Kay Huebner; Alexander Mazo; Eli Canaani
Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax.
Oncogene 1997;15(5):549-60.
1997: Srinivasa M Srinivasula; M Ahmad; S Ottilie; Florencia Bullrich; S Banks; Youli Wang; Teresa Fernandes-Alnemri; Carlo M Croce; Gerald Litwack; Kevin J Tomaselli; Robert C Armstrong; Emad S Alnemri
FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis.
The Journal of biological chemistry 1997;272(30):18542-5.
1997: Claudio Sorio; P Melotti; D D'Arcangelo; Jeannine M Mendrola; B Calabretta; Carlo M Croce; K Huebner
Receptor protein tyrosine phosphatase gamma, Ptp gamma, regulates hematopoietic differentiation.
Blood 1997;90(1):49-57.
1997: D Rasio; Yoshiki Murakumo; D Robbins; T Roth; A Silver; Massimo Negrini; C Schmidt; J Burczak; Richard Fishel; Carlo M Croce
Characterization of the human homologue of RAD54: a gene located on chromosome 1p32 at a region of high loss of heterozygosity in breast tumors.
Cancer research 1997;57(12):2378-83.
1997: Kay Huebner; P Hadaczek; Z Siprashvili; Teresa Druck; Carlo M Croce
The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B.
Biochimica et biophysica acta 1997;1332(3):M65-70.
1997: Gabriella Sozzi; L Sard; L De Gregorio; Antonio Marchetti; K Musso; Fiamma Buttitta; S Tornielli; S Pellegrini; Maria L Veronese; Giacomo Manenti; Matteo Incarbone; Antonio Chella; Carlo Alberto Angeletti; Ugo Pastorino; Kay Huebner; G Bevilaqua; Silvana Pilotti; Carlo M Croce; Marco A Pierotti
Association between cigarette smoking and FHIT gene alterations in lung cancer.
Cancer research 1997;57(11):2121-3.
1997: Gianluigi Condorelli; A Tocci; Rosanna Botta; francesco facchiano; Ugo Testa; Luigi Vitelli; Mauro Valtieri; Carlo M Croce; Cesare Peschle
Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative and antiapoptotic effects coupled with a differentiation blockade.
Molecular and cellular biology 1997;17(5):2954-69.
1997: Drazen Zimonjic; Teresa Druck; M Ohta; K Kastury; Carlo M Croce; Nicholas C Popescu; Kay Huebner
Positions of chromosome 3p14.2 fragile sites (FRA3B) within the FHIT gene.
Cancer research 1997;57(6):1166-70.
1997: Antonio Cuneo; Renato Bigoni; Massimo Negrini; Florencia Bullrich; Maria L Veronese; Maria Grazia Roberti; Antonella Bardi; Gian Matteo Rigolin; P Cavazzini; Carlo M Croce; Gianluigi Castoldi
Cytogenetic and interphase cytogenetic characterization of atypical chronic lymphocytic leukemia carrying BCL1 translocation.
Cancer research 1997;57(6):1144-50.
1997: Teresa Druck; P Hadaczek; T B Fu; M Ohta; Z Siprashvili; Raffaele Baffa; Massimo Negrini; K Kastury; Maria L Veronese; D Rosen; J Rothstein; Peter McCue; M G Cotticelli; H Inoue; Carlo M Croce; Kay Huebner
Structure and expression of the human FHIT gene in normal and tumor cells.
Cancer research 1997;57(3):504-12.
1997: S Haldar; A Basu; Carlo M Croce
Bcl2 is the guardian of microtubule integrity.
Cancer research 1997;57(2):229-33.
1997: N Jena; C Martín-Seisdedos; P McCue; Carlo M Croce
BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye.
Experimental cell research 1997;230(1):28-37.
1996: Gianluigi Condorelli; francesco facchiano; Mauro Valtieri; E Proietti; Luigi Vitelli; V Lulli; Kay Huebner; Cesare Peschle; Carlo M Croce
T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice.
Cancer research 1996;56(22):5113-9.
1996: D Leshkowitz; O Rozenblatt; Tatsuya Nakamura; T Yano; F Dautry; Carlo M Croce; Eli Canaani
ALL-1 interacts with unr, a protein containing multiple cold shock domains.
Oncogene 1996;13(9):2027-31.
1996: Florencia Bullrich; Maria L Veronese; Shinichi Kitada; Jesper Jurlander; Michael A Caligiuri; J C Reed; Carlo M Croce
Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia.
Blood 1996;88(8):3109-15.
1996: Larry D Barnes; Preston N Garrison; Z Siprashvili; Andrzej Guranowski; Angela K Robinson; Stephen W Ingram; Carlo M Croce; M Ohta; Kay Huebner
Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase.
Biochemistry 1996;35(36):11529-35.
1996: L Virgilio; M Shuster; S M Gollin; M L Veronese; M Ohta; Kay Huebner; Carlo M Croce
FHIT gene alterations in head and neck squamous cell carcinomas.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9770-5.
1996: Florencia Bullrich; Teresa Fernandes-Alnemri; Gerald Litwack; Emad S Alnemri; Carlo M Croce
Chromosomal mapping of cell death proteases CPP32, MCH2, and MCH3.
Genomics 1996;36(2):362-5.
1996: R Bigoni; Massimo Negrini; Maria L Veronese; Antonio Cuneo; G L Castoldi; Carlo M Croce
Characterization of t(11;14) translocation in mantle cell lymphoma by fluorescent in situ hybridization.
Oncogene 1996;13(4):797-802.
1996: Massimo Negrini; Carmen Monaco; I Vorechovsky; M Ohta; Teresa Druck; Raffaele Baffa; Kay Huebner; Carlo M Croce
The FHIT gene at 3p14.2 is abnormal in breast carcinomas.
Cancer research 1996;56(14):3173-9.
1996: Gabriella Sozzi; Hansjuerg Alder; S Tornielli; V Corletto; Raffaele Baffa; Maria L Veronese; Massimo Negrini; Silvana Pilotti; Marco A Pierotti; Kay Huebner; Carlo M Croce
Aberrant FHIT transcripts in Merkel cell carcinoma.
Cancer research 1996;56(11):2472-4.
1996: D Rasio; S A Schichman; Massimo Negrini; Eli Canaani; Carlo M Croce
Complete exon structure of the ALL1 gene.
Cancer research 1996;56(8):1766-9.
1996: Gabriella Sozzi; Maria L Veronese; Massimo Negrini; Raffaele Baffa; M G Cotticelli; H Inoue; S Tornielli; Silvana Pilotti; L De Gregorio; Ugo Pastorino; Marco A Pierotti; M Ohta; Kay Huebner; Carlo M Croce
The FHIT gene 3p14.2 is abnormal in lung cancer.
Cell 1996;85(1):17-26.
1996: Michael A Caligiuri; Matthew P Strout; S A Schichman; Krzysztof Mrózek; Diane C Arthur; Geoffrey P Herzig; Maria R Baer; Charles Alan Schiffer; Kirsti Heinonen; S Knuutila; Tapio Nousiainen; T Ruutu; A W Block; P Schulman; J Pedersen-Bjergaard; Carlo M Croce; Clara D Bloomfield
Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11.
Cancer research 1996;56(6):1418-25.
1996: S Haldar; J Chintapalli; Carlo M Croce
Taxol induces bcl-2 phosphorylation and death of prostate cancer cells.
Cancer research 1996;56(6):1253-5.
1996: Vincenzo Fidanza; P Melotti; T Yano; Tatsuya Nakamura; A Bradley; Eli Canaani; B Calabretta; Carlo M Croce
Double knockout of the ALL-1 gene blocks hematopoietic differentiation in vitro.
Cancer research 1996;56(6):1179-83.
1996: M Ohta; D Berd; M Shimizu; H Nagai; M Mastrangelo; J A Shields; C L Shields; Carlo M Croce; K Huebner
Deletion mapping of chromosome region 9p21-p22 surrounding the CDKN2 locus in melanoma.
International journal of cancer. Journal international du cancer 1996;65(6):762-7.
1996: K Kastury; Raffaele Baffa; Teresa Druck; M Ohta; M G Cotticelli; H Inoue; Massimo Negrini; M Rugge; D Huang; Carlo M Croce; J Palazzo; Kay Huebner
Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.
Cancer research 1996;56(5):978-83.
1996: M Ohta; H Inoue; M G Cotticelli; K Kastury; Raffaele Baffa; J Palazzo; Z Siprashvili; Masaki Mori; Peter McCue; Teresa Druck; Carlo M Croce; Kay Huebner
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers.
Cell 1996;84(4):587-97.
1996: Maria L Veronese; Florencia Bullrich; Massimo Negrini; Carlo M Croce
The t(6;16)(p21;q22) chromosome translocation in the LNCaP prostate carcinoma cell line results in a tpc/hpr fusion gene.
Cancer research 1996;56(4):728-32.
1996: Raffaele Baffa; Massimo Negrini; B Mandes; M Rugge; G N Ranzani; S Hirohashi; Carlo M Croce
Loss of heterozygosity for chromosome 11 in adenocarcinoma of the stomach.
Cancer research 1996;56(2):268-72.
1995: R Prasad; T Yano; Claudio Sorio; Tatsuya Nakamura; R Rallapalli; Yansong Gu; D Leshkowitz; Carlo M Croce; Eli Canaani
Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12160-4.
1995: D Rasio; Massimo Negrini; Carlo M Croce
Genomic organization of the ATM locus involved in ataxia-telangiectasia.
Cancer research 1995;55(24):6053-7.
1995: Teresa Fernandes-Alnemri; A Takahashi; R Armstrong; J Krebs; Lawrence C Fritz; Kevin J Tomaselli; L Wang; Z Yu; Carlo M Croce; G Salveson
Mch3, a novel human apoptotic cysteine protease highly related to CPP32.
Cancer research 1995;55(24):6045-52.
1995: Claudio Sorio; Jeannine M Mendrola; Z Lou; S LaForgia; Carlo M Croce; Kay Huebner
Characterization of the receptor protein tyrosine phosphatase gene product PTP gamma: binding and activation by triphosphorylated nucleosides.
Cancer research 1995;55(21):4855-64.
1995: D Rasio; Massimo Negrini; G Manenti; T A Dragani; Carlo M Croce
Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: identification of three independent regions.
Cancer research 1995;55(18):3988-91.
1995: Maria Grazia Narducci; L Virgilio; M Isobe; A Stoppacciaro; R Elli; Massimo Fiorilli; Maurizio Carbonari; A Antonelli; Luciana Chessa; Carlo M Croce; Giandomenico Russo
TCL1 oncogene activation in preleukemic T cells from a case of ataxia-telangiectasia.
Blood 1995;86(6):2358-64.
1995: Massimo Negrini; Antonio Cuneo; Tatsuya Nakamura; Raffaele Baffa; Silvia Sabbioni; Hansjuerg Alder; G Castoldi; Carlo M Croce
A novel t(9;11)(p22;q23) with ALL-1 gene rearrangement associated with progression of a myeloproliferative disorder to acute myeloid leukemia.
Cancer genetics and cytogenetics 1995;83(1):65-70.
1995: Massimo Negrini; Silvia Sabbioni; M Ohta; Maria L Veronese; S Rattan; C Junien; Carlo M Croce
Seven megabase yeast artificial chromosome contig at region 11p15: identification of a yeast artificial chromosome spanning the breakpoint of a chromosomal translocation found in a case of Beckwith-Wiedemann syndrome.
Cancer research 1995;55(13):2904-9.
1995: Raffaele Baffa; Massimo Negrini; S A Schichman; Kay Huebner; Carlo M Croce
Involvement of the ALL-1 gene in a solid tumor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4922-6.
1995: S Haldar; N Jena; Carlo M Croce
Inactivation of Bcl-2 by phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4507-11.
1995: A Magdalinski; H Drwinga; Pamela Crilley; J Lasota; Irina Brodsky; Carlo M Croce; P C Nowell; D I Marks
Translocation 11;14 in newly diagnosed chronic myelogenous leukemia.
Cancer genetics and cytogenetics 1995;81(1):24-7.
1995: M L Veronese; M Ohta; J Finan; P C Nowell; Carlo M Croce
Detection of myc translocations in lymphoma cells by fluorescence in situ hybridization with yeast artificial chromosomes.
Blood 1995;85(8):2132-8.
1995: H Nagai; Massimo Negrini; S L Carter; D R Gillum; A L Rosenberg; Gordon Schwartz; Carlo M Croce
Detection and cloning of a common region of loss of heterozygosity at chromosome 1p in breast cancer.
Cancer research 1995;55(8):1752-7.
1995: Florencia Bullrich; TK MacLachlan; Nianli Sang; Teresa Druck; Maria L Veronese; Steven Allen; Nicholas Chiorazzi; Andrew Koff; K Heubner; Carlo M Croce
Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer.
Cancer research 1995;55(6):1199-205.
1995: S A Schichman; Eli Canaani; Carlo M Croce
Self-fusion of the ALL1 gene. A new genetic mechanism for acute leukemia.
JAMA : the journal of the American Medical Association 1995;273(7):571-6.
1995: S A Schichman; Carlo M Croce
Approaches to the identification and molecular cloning of chromosome breakpoints.
Methods in enzymology 1995;254():321-34.
1995: Eli Canaani; P C Nowell; Carlo M Croce
Molecular genetics of 11q23 chromosome translocations.
Advances in cancer research 1995;66():213-34.
1994: L Virgilio; Maria Grazia Narducci; M Isobe; L G Billips; Max D Cooper; Carlo M Croce; Giandomenico Russo
Identification of the TCL1 gene involved in T-cell malignancies.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12530-4.
1994: T B Fu; L Virgilio; Maria Grazia Narducci; A Facchiano; Giandomenico Russo; Carlo M Croce
Characterization and localization of the TCL-1 oncogene product.
Cancer research 1994;54(24):6297-301.
1994: M Monne; Carlo M Croce; H Yu; E P Diamandis
Molecular characterization of prostate-specific antigen messenger RNA expressed in breast tumors.
Cancer research 1994;54(24):6344-7.
1994: S Haldar; N Jena; G C DuBois; S Takayama; J C Reed; S S Fu; Carlo M Croce
Purification and characterization of the bcl-2 protein.
Archives of biochemistry and biophysics 1994;315(2):483-8.
1994: S L Carter; Massimo Negrini; Raffaele Baffa; D R Gillum; A L Rosenberg; Gordon Schwartz; Carlo M Croce
Loss of heterozygosity at 11q22-q23 in breast cancer.
Cancer research 1994;54(23):6270-4.
1994: S Haldar; N Jena; Carlo M Croce
Antiapoptosis potential of bcl-2 oncogene by dephosphorylation.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72(11-12):455-62.
1994: M Ohta; H Nagai; M Shimizu; D Rasio; D Berd; M Mastrangelo; A D Singh; J A Shields; C L Shields; Carlo M Croce
Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma.
Cancer research 1994;54(20):5269-72.
1994: R Prasad; D Leshkowitz; Yansong Gu; Hansjuerg Alder; Tatsuya Nakamura; H Saito; Kay Huebner; R Berger; Carlo M Croce; Eli Canaani
Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):8107-11.
1994: S A Schichman; Michael A Caligiuri; Matthew P Strout; S L Carter; Yansong Gu; Eli Canaani; Clara D Bloomfield; Carlo M Croce
ALL-1 tandem duplication in acute myeloid leukemia with a normal karyotype involves homologous recombination between Alu elements.
Cancer research 1994;54(16):4277-80.
1994: William E Carson; S Haldar; Robert A Baiocchi; Carlo M Croce; Michael A Caligiuri
The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(16):7553-7.
1994: S A Schichman; Michael A Caligiuri; Yansong Gu; Matthew P Strout; Eli Canaani; Clara D Bloomfield; Carlo M Croce
ALL-1 partial duplication in acute leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6236-9.
1994: Yansong Gu; Hansjuerg Alder; Tatsuya Nakamura; S A Schichman; R Prasad; O Canaani; H Saito; Carlo M Croce; Eli Canaani
Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia.
Cancer research 1994;54(9):2327-30.
1994: K Kastury; J Li; Teresa Druck; H Su; P K Vogt; Carlo M Croce; Kay Huebner
The human homologue of the retroviral oncogene qin maps to chromosome 14q13.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3616-8.
1994: S Haldar; Massimo Negrini; M Monne; Silvia Sabbioni; Carlo M Croce
Down-regulation of bcl-2 by p53 in breast cancer cells.
Cancer research 1994;54(8):2095-7.
1994: Massimo Negrini; Silvia Sabbioni; S Haldar; Laura Possati; A Castagnoli; Alfredo Corallini; Giuseppe Barbanti-Brodano; Carlo M Croce
Tumor and growth suppression of breast cancer cells by chromosome 17-associated functions.
Cancer research 1994;54(7):1818-24.
1994: Massimo Negrini; Silvia Sabbioni; Laura Possati; S Rattan; Alfredo Corallini; Giuseppe Barbanti-Brodano; Carlo M Croce
Suppression of tumorigenicity of breast cancer cells by microcell-mediated chromosome transfer: studies on chromosomes 6 and 11.
Cancer research 1994;54(5):1331-6.
1994: Michael A Caligiuri; S A Schichman; Matthew P Strout; Krzysztof Mrózek; Maria R Baer; Stanley R Frankel; M Barcos; Geoffrey P Herzig; Carlo M Croce; Clara D Bloomfield
Molecular rearrangement of the ALL-1 gene in acute myeloid leukemia without cytogenetic evidence of 11q23 chromosomal translocations.
Cancer research 1994;54(2):370-3.
1993: C E Gauwerky; Carlo M Croce
Chromosomal translocations in leukaemia.
Seminars in cancer biology 1993;4(6):333-40.
1993: L Virgilio; M Isobe; Maria Grazia Narducci; P Carotenuto; B Camerini; N Kurosawa; Carlo M Croce; Giandomenico Russo
Chromosome walking on the TCL1 locus involved in T-cell neoplasia.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9275-9.
1993: Massimo Negrini; Carolyn A Felix; C Martin; Beverly J Lange; Tatsuya Nakamura; Eli Canaani; Carlo M Croce
Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia.
Cancer research 1993;53(19):4489-92.
1993: Carlo M Croce
Molecular biology of lymphomas.
Seminars in oncology 1993;20(5 Suppl 5):31-46.
1993: Q Ma; Hansjuerg Alder; K K Nelson; D Chatterjee; Yansong Gu; Tatsuya Nakamura; Eli Canaani; Carlo M Croce; Linda D Siracusa; Arthur M Buchberg
Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6350-4.
1993: Z Lou; K Kastury; Pamela Crilley; J Lasota; Teresa Druck; Carlo M Croce; Kay Huebner
Characterization of human bone marrow-derived closed circular DNA clones.
Genes, chromosomes & cancer 1993;7(1):15-27.
1993: Kay Huebner; Teresa Druck; S LaForgia; J Lasota; Carlo M Croce; Luisa Lanfrancone; Emilio Donti; G Pengue; Girolama La Mantia; Pier Giuseppe Pelicci
Chromosomal localization of four human zinc finger cDNAs.
Human genetics 1993;91(3):217-22.
1992: Yansong Gu; Tatsuya Nakamura; Hansjuerg Alder; R Prasad; O Canaani; G Cimino; Carlo M Croce; Eli Canaani
The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene.
Cell 1992;71(4):701-8.
1992: Yansong Gu; G Cimino; Hansjuerg Alder; Tatsuya Nakamura; R Prasad; O Canaani; D T Moir; C Jones; P C Nowell; Carlo M Croce
The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10464-8.
1992: Jose G Moreno; Carlo M Croce; R Fischer; M Monne; P Vihko; S G Mulholland; Leonard G Gomella
Detection of hematogenous micrometastasis in patients with prostate cancer.
Cancer research 1992;52(21):6110-2.
1992: Emad S Alnemri; Noreen M Robertson; T F Fernandes; Carlo M Croce; Gerald Litwack
Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7295-9.
1992: Emad S Alnemri; T F Fernandes; S Haldar; Carlo M Croce; Gerald Litwack
Involvement of BCL-2 in glucocorticoid-induced apoptosis of human pre-B-leukemias.
Cancer research 1992;52(2):491-5.
1991: G Cimino; D T Moir; O Canaani; K Williams; W M Crist; S Katzav; Linda Cannizzaro; B Lange; P C Nowell; Carlo M Croce
Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations.
Cancer research 1991;51(24):6712-4.
1991: Carlo M Croce
Genetic approaches to the study of the molecular basis of human cancer.
Cancer research 1991;51(18 Suppl):5015s-5018s.
1991: C Barletta; Teresa Druck; S LaForgia; B Calabretta; Harry A Drabkin; D Patterson; Carlo M Croce; Kay Huebner
Chromosome locations of the MYB related genes, AMYB and BMYB.
Cancer research 1991;51(14):3821-4.
1989: E Fainstein; M Einat; E Gokkel; C Marcelle; Carlo M Croce; Robert Peter Gale; Eli Canaani
Nucleotide sequence analysis of human abl and bcr-abl cDNAs.
Oncogene 1989;4(12):1477-81.
1987: E Fainstein; C Marcelle; A Rosner; Eli Canaani; Robert Peter Gale; O Dreazen; S D Smith; Carlo M Croce
A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia.
Nature 1987;330(6146):386-8.