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Daan Crommelin

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Chris Holloway; Sau Larry Lee; Beatriz Silva Lima; Jan Muller-Berghaus; J Michael Nicholas; Janet S Wyatt; Daan J A Crommelin
Scientific considerations for complex drugs in light of established and emerging regulatory guidance.
Malcolm Rowland; Dennis A Smith; G T Tucker; Luc Besançon; Daan J A Crommelin; Christian R Noe; Carl C Peck; Mario L Rocci; Vinod P Shah
Impact of the pharmaceutical sciences on health care: a reflection over the past 50 years.
Peter R Luijten; Chrit T Moonen; Gert Storm; Guus A M S van Dongen; Daan J A Crommelin
Public-private partnerships in translational medicine: concepts and practical examples.

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2012: Chris Holloway; Sau Larry Lee; Beatriz Silva Lima; Jan Muller-Berghaus; J Michael Nicholas; Janet S Wyatt; Daan J A Crommelin
Scientific considerations for complex drugs in light of established and emerging regulatory guidance.
Annals of the New York Academy of Sciences 2012;1276():26-36.
2012: Malcolm Rowland; Dennis A Smith; G T Tucker; Luc Besançon; Daan J A Crommelin; Christian R Noe; Carl C Peck; Mario L Rocci; Vinod P Shah
Impact of the pharmaceutical sciences on health care: a reflection over the past 50 years.
Journal of pharmaceutical sciences 2012;101(11):4075-99.
2012: Peter R Luijten; Chrit T Moonen; Gert Storm; Guus A M S van Dongen; Daan J A Crommelin
Public-private partnerships in translational medicine: concepts and practical examples.
Journal of controlled release : official journal of the Controlled Release Society 2012;161(2):416-21.
2012: Tom R Denee; Michel Goldman; Daan J A Crommelin; Antoine Juliens; Jan A M Raaijmakers; Arnold Sneekes; Pieter Stolk; Jorg W Janssen
Measuring the value of public-private partnerships in the pharmaceutical sciences.
Nature reviews. Drug discovery 2012;11(5):419.
2012: Wim Jiskoot; C Russell Middaugh; Theodore W Randolph; Christian Schöneich; David B Volkin; Gerhard Winter; Daan J A Crommelin; Wolfgang Friess; John F Carpenter
Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release.
Journal of pharmaceutical sciences 2012;101(3):946-54.
2011: Ethlinn V B van Gaal; Ronald S Oosting; Roel van Eijk; Daan J A Crommelin; Wim E Hennink; Robbert Jan Kok; Enrico Mastrobattista
How to screen non-viral gene delivery systems in vitro?
Journal of controlled release : official journal of the Controlled Release Society 2011;154(3):218-32.
2011: Daan J A Crommelin; Gert Storm; Peter Luijten
'Personalised medicine' through 'personalised medicines': time to integrate advanced, non-invasive imaging approaches and smart drug delivery systems.
International journal of pharmaceutics 2011;415(1-2):5-8.
2011: Ethlinn V B van Gaal; Ronald S Oosting; Roel van Eijk; Marta Bakowska; Daan J A Crommelin; Dries Feyen; Wim E Hennink; Robbert Jan Kok; Enrico Mastrobattista
DNA nuclear targeting sequences for non-viral gene delivery.
Pharmaceutical research 2011;28(7):1707-22.
2011: Maryam Amidi; Daan J A Crommelin; Markus de Raad; Wim E Hennink; Enrico Mastrobattista
Antigen-expressing immunostimulatory liposomes as a genetically programmable synthetic vaccine.
Systems and synthetic biology 2011;5(1-2):21-31.
2011: Huub Schellekens; Ety Klinger; Stefan Mühlebach; Jean-Francois Brin; Gert Storm; Daan J A Crommelin
The therapeutic equivalence of complex drugs.
Regulatory toxicology and pharmacology : RTP 2011;59(1):176-83.
2010: Albert J van Hell; Andrey Klymchenko; Pepijn P Burgers; Ed E. Moret; Wim Jiskoot; Wim E Hennink; Daan J A Crommelin; Enrico Mastrobattista
Conformation and intermolecular interactions of SA2 peptides self-assembled into vesicles.
The journal of physical chemistry. B 2010;114(34):11046-52.
2010: Amir H Ghassemi; Mies J van Steenbergen; Herre Talsma; Cornelus F van Nostrum; Daan J A Crommelin; Wim E Hennink
Hydrophilic polyester microspheres: effect of molecular weight and copolymer composition on release of BSA.
Pharmaceutical research 2010;27(9):2008-17.
2010: Ethlinn V B van Gaal; Ronald S Oosting; Wim E Hennink; Daan J A Crommelin; Enrico Mastrobattista
Junk DNA enhances pEI-based non-viral gene delivery.
International journal of pharmaceutics 2010;390(1):76-83.
2010: John F Carpenter; Theodore W Randolph; Wim Jiskoot; Daan J A Crommelin; C Russell Middaugh; Gerhard Winter
Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products.
Journal of pharmaceutical sciences 2010;99(5):2200-8.
2010: Vinod P Shah; Luc J R Besancon; Pieter Stolk; Geoffrey Tucker; Daan J A Crommelin
The pharmaceutical sciences in 2020: report of a conference organized by the board of pharmaceutical sciences of the International Pharmaceutical Federation (FIP).
Pharmaceutical research 2010;27(3):396-9.
2010: Maryam Amidi; Markus de Raad; Helma de Graauw; Dave van Ditmarsch; Wim E Hennink; Daan J A Crommelin; Enrico Mastrobattista
Optimization and quantification of protein synthesis inside liposomes.
Journal of liposome research 2010;20(1):73-83.
2010: Daan J A Crommelin; Kinam Park; Alexander Florence
Pharmaceutical nanotechnology: Unmet needs in drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(3):263-4.
2010: Albert J van Hell; Marjan M Fretz; Daan J A Crommelin; Wim E Hennink; Enrico Mastrobattista
Peptide nanocarriers for intracellular delivery of photosensitizers.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(3):347-53.
2009: Vinod P Shah; Luc J R Besançon; Pieter Stolk; Geoffrey Tucker; Daan J A Crommelin
The pharmaceutical sciences in 2020--report of a conference organized by the Board of Pharmaceutical Sciences of the International Pharmaceutical Federation (FIP).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;38(5):419-25.
2009: Albert J van Hell; Daan J A Crommelin; Wim E Hennink; Enrico Mastrobattista
Stabilization of peptide vesicles by introducing inter-peptide disulfide bonds.
Pharmaceutical research 2009;26(9):2186-93.
2009: John F Carpenter; Theodore W Randolph; Wim Jiskoot; Daan J A Crommelin; C Russell Middaugh; Gerhard Winter; Ying-Xin Fan; Susan Kirshner; Daniela Verthelyi; Steven Kozlowski; Kathleen A Clouse; Patrick G Swann; Amy Rosenberg; Barry Cherney
Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality.
Journal of pharmaceutical sciences 2009;98(4):1201-5.
2008: Andréanne Bouchard; Natasa Jovanović; Anne H de Boer; Angel Martín; Wim Jiskoot; Daan J A Crommelin; Gerard W Hofland; Geert-Jan Witkamp
Effect of the spraying conditions and nozzle design on the shape and size distribution of particles obtained with supercritical fluid drying.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(1):389-401.
2008: Maryam Amidi; Kevin M Krudys; Cor J Snel; Daan J A Crommelin; Oscar Della-Pasqua; Wim E Hennink; Wim Jiskoot
Efficacy of pulmonary insulin delivery in diabetic rats: use of a model-based approach in the evaluation of insulin powder formulations.
Journal of controlled release : official journal of the Controlled Release Society 2008;127(3):257-66.
2008: Myrra G Carstens; Pascal H J L F de Jong; Cornelus F van Nostrum; Johan Kemmink; Ruud Verrijk; L G J de Leede; Daan J A Crommelin; Wim E Hennink
The effect of core composition in biodegradable oligomeric micelles as taxane formulations.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;68(3):596-606.
2008: Andréanne Bouchard; Natasa Jovanović; Gerard W Hofland; Wim Jiskoot; Eduardo Mendes; Daan J A Crommelin; Geert-Jan Witkamp
Supercritical fluid drying of carbohydrates: selection of suitable excipients and process conditions.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;68(3):781-94.
2008: Maryam Amidi; Hubert C Pellikaan; Anne H de Boer; Daan J A Crommelin; Wim E Hennink; Wim Jiskoot
Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;68(2):191-200.
2008: Natasa Jovanović; Andréanne Bouchard; Gerard W Hofland; Geert-Jan Witkamp; Daan J A Crommelin; Wim Jiskoot
Stabilization of IgG by supercritical fluid drying: optimization of formulation and process parameters.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;68(2):183-90.
2008: Natasa Jovanović; Andréanne Bouchard; Marc Sutter; Michiel Van Speybroeck; Gerard W Hofland; Geert-Jan Witkamp; Daan J A Crommelin; Wim Jiskoot
Stable sugar-based protein formulations by supercritical fluid drying.
International journal of pharmaceutics 2008;346(1-2):102-8.
2008: Myrra G Carstens; Cornelus F van Nostrum; Ruud Verrijk; L G J de Leede; Daan J A Crommelin; Wim E Hennink
A mechanistic study on the chemical and enzymatic degradation of PEG-Oligo(epsilon-caprolactone) micelles.
Journal of pharmaceutical sciences 2008;97(1):506-18.
2007: K D F Vlugt-Wensink; R de Vrueh; MG Gresnigt; Cok M Hoogerbrugge; Sylvia C van Buul-Offers; L G J de Leede; L G W Sterkman; Daan J A Crommelin; Wim E Hennink; Ruud Verrijk
Preclinical and clinical in vitro in vivo correlation of an hGH dextran microsphere formulation.
Pharmaceutical research 2007;24(12):2239-48.
2007: K D F Vlugt-Wensink; Y J Meijer; Mies J van Steenbergen; Ruud Verrijk; Wim Jiskoot; Daan J A Crommelin; Wim E Hennink
Effect of excipients on the encapsulation efficiency and release of human growth hormone from dextran microspheres.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;67(3):589-96.
2007: Bernard Metz; Wim Jiskoot; Dirk Mekkes; Robert Kingma; Wim E Hennink; Daan J A Crommelin; Gideon F A Kersten
Quality control of routine, experimental and real-time aged diphtheria toxoids by in vitro analytical techniques.
Vaccine 2007;25(39-40):6863-71.
2007: Maryam Amidi; Hubert C Pellikaan; Hoang Hirschberg; Anne H de Boer; Daan J A Crommelin; Wim E Hennink; Gideon F A Kersten; Wim Jiskoot
Diphtheria toxoid-containing microparticulate powder formulations for pulmonary vaccination: preparation, characterization and evaluation in guinea pigs.
Vaccine 2007;25(37-38):6818-29.
2007: Albert J van Hell; Cristina I C A Costa; Frits M Flesch; Marc Sutter; Wim Jiskoot; Daan J A Crommelin; Wim E Hennink; Enrico Mastrobattista
Self-assembly of recombinant amphiphilic oligopeptides into vesicles.
Biomacromolecules 2007;8(9):2753-61.
2007: Marieke van der Aa; Ulrich S Huth; S Y Häfele; R Schubert; Ronald S Oosting; Enrico Mastrobattista; Wim E Hennink; Regine Peschka-Süss; Gerben A Koning; Daan J A Crommelin
Cellular uptake of cationic polymer-DNA complexes via caveolae plays a pivotal role in gene transfection in COS-7 cells.
Pharmaceutical research 2007;24(8):1590-8.
2007: Maryam Amidi; Stefan G Romeijn; Jan Verhoef; Hans E Junginger; Laura Bungener; Anke Huckriede; Daan J A Crommelin; Wim Jiskoot
N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model.
Vaccine 2007;25(1):144-53.
2006: Myrra G Carstens; Cornelus F van Nostrum; Aissa Ramzi; L G J de Leede; Daan J A Crommelin; Wim E Hennink
Self-assembly of PEG-oligolactates with monodisperse hydrophobic blocks.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e40-1.
2006: K D F Vlugt-Wensink; Xulin Jiang; Geert Schotman; Govert Kruijtzer; Arjen Vredenberg; Jin T Chung; Zhibing Zhang; Cees Versluis; Delphine Ramos; Ruud Verrijk; Wim Jiskoot; Daan J A Crommelin; Wim E Hennink
In vitro degradation behavior of microspheres based on cross-linked dextran.
Biomacromolecules 2006;7(11):2983-90.
2006: Ethlinn V B van Gaal; Wim E Hennink; Daan J A Crommelin; Enrico Mastrobattista
Plasmid engineering for controlled and sustained gene expression for nonviral gene therapy.
Pharmaceutical research 2006;23(6):1053-74.
2006: Bernard Metz; Gideon F A Kersten; Gino J E Baart; Annemieke de Jong; Hugo D Meiring; Jan ten Hove; Mies J van Steenbergen; Wim E Hennink; Daan J A Crommelin; Wim Jiskoot
Identification of formaldehyde-induced modifications in proteins: reactions with insulin.
Bioconjugate chemistry 2006;17(3):815-22.
2006: Suzanne Hermeling; Huub Schellekens; Coen Maas; Martijn F B G Gebbink; Daan J A Crommelin; Wim Jiskoot
Antibody response to aggregated human interferon alpha2b in wild-type and transgenic immune tolerant mice depends on type and level of aggregation.
Journal of pharmaceutical sciences 2006;95(5):1084-96.
2006: K D F Vlugt-Wensink; Thijs J H Vlugt; Wim Jiskoot; Daan J A Crommelin; Ruud Verrijk; Wim E Hennink
Modeling the release of proteins from degrading crosslinked dextran microspheres using kinetic Monte Carlo simulations.
Journal of controlled release : official journal of the Controlled Release Society 2006;111(1-2):117-27.
2006: Marieke van der Aa; Enrico Mastrobattista; Ronald S Oosting; Wim E Hennink; Gerben A Koning; Daan J A Crommelin
The nuclear pore complex: the gateway to successful nonviral gene delivery.
Pharmaceutical research 2006;23(3):447-59.
2006: Suzanne Hermeling; Wim Jiskoot; Daan J A Crommelin; Huub Schellekens
Reaction to the paper: interaction of polysorbate 80 with erythropoietin: a case study in protein-surfactant interactions.
Pharmaceutical research 2006;23(3):641-2; author reply 643-4.
2006: Natasa Jovanović; Andréanne Bouchard; Gerard W Hofland; Geert-Jan Witkamp; Daan J A Crommelin; Wim Jiskoot
Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;27(4):336-45.
2006: Enrico Mastrobattista; Marieke van der Aa; Wim E Hennink; Daan J A Crommelin
Artificial viruses: a nanotechnological approach to gene delivery.
Nature reviews. Drug discovery 2006;5(2):115-21.
2005: Suzanne Hermeling; Liliana Aranha; J Mirjam A Damen; Monique Slijper; Huub Schellekens; Daan J A Crommelin; Wim Jiskoot
Structural characterization and immunogenicity in wild-type and immune tolerant mice of degraded recombinant human interferon alpha2b.
Pharmaceutical research 2005;22(12):1997-2006.
2005: Myrra G Carstens; Cornelus F van Nostrum; Aissa Ramzi; Johannes D Meeldijk; Ruud Verrijk; Leo L de Leede; Daan J A Crommelin; Wim E Hennink
Poly(ethylene glycol)--oligolactates with monodisperse hydrophobic blocks: preparation, characterization, and behavior in water.
Langmuir : the ACS journal of surfaces and colloids 2005;21(24):11446-54.
2005: Yixian Zhao; Yair Benita; Martin C Lok; Betsy Kuipers; Peter van der Ley; Wim Jiskoot; Wim E Hennink; Daan J A Crommelin; Ronald S Oosting
Multi-antigen immunization using IgG binding domain ZZ as carrier.
Vaccine 2005;23(43):5082-90.
2005: Carmen Arigita; Thomas Luijkx; Wim Jiskoot; Martien C M Poelen; Wim E Hennink; Daan J A Crommelin; Peter van der Ley; Cecile Van Els; Gideon F A Kersten
Well-defined and potent liposomal meningococcal B vaccines adjuvated with LPS derivatives.
Vaccine 2005;23(43):5091-8.
2005: Suzanne Hermeling; Wim Jiskoot; Daan J A Crommelin; Claus Bornaes; Huub Schellekens
Development of a transgenic mouse model immune tolerant for human interferon Beta.
Pharmaceutical research 2005;22(6):847-51.
2005: Corine C Visser; Sanja Stevanović; L Heleen Voorwinden; Louis van Bloois; Pieter J Gaillard; Meindert Danhof; Daan J A Crommelin; Albertus G de Boer
Targeting liposomes with protein drugs to the blood-brain barrier in vitro.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;25(2-3):299-305.
2005: Arjen M Funhoff; Sophie Monge; Rosalie Teeuwen; Gerben A Koning; Nancy M E Schuurmans-Nieuwenbroek; Daan J A Crommelin; David M Haddleton; Wim E Hennink; Cornelus F van Nostrum
PEG shielded polymeric double-layered micelles for gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2005;102(3):711-24.
2005: Patrick Couvreur; Diane Barguer; Daan J A Crommelin; Dominique Duchêne; Joachim W Engels; David J Kerr; Povl Krogsgaard-Larsen; Dirk K Meijer; Rodolfo Paoletti; Ernst Wagner
EUFEPS report. Contribution of academic research to discovery and development of medicines: current status and future opportunities.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;24(2-3):245-52.
2005: Marieke van der Aa; Gerben A Koning; Christine d'Oliveira; Ronald S Oosting; K J Wilschut; Wim E Hennink; Daan J A Crommelin
An NLS peptide covalently linked to linear DNA does not enhance transfection efficiency of cationic polymer based gene delivery systems.
The journal of gene medicine 2005;7(2):208-17.
2005: Marieke van der Aa; Gerben A Koning; Jan van der Gugten; Christine d'Oliveira; Ronald S Oosting; Wim E Hennink; Daan J A Crommelin
Covalent attachment of an NLS-peptide to linear dna does not enhance transfection efficiency of cationic polymer based gene delivery systems.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):395-7.
2005: Arjen M Funhoff; Cornelus F van Nostrum; Martin C Lok; John A W Kruijtzer; Daan J A Crommelin; Wim E Hennink
Cationic polymethacrylates with covalently linked membrane destabilizing peptides as gene delivery vectors.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):233-46.
2005: Daan J A Crommelin; Theresa Bermejo; Marco Bissig; Jaak Damiaans; Irene Krämer; Patrick Rambourg; Giovanna Scroccaro; Borut Strukelj; Roger Tredree; Claudio Ronco
Biosimilars, generic versions of the first generation of therapeutic proteins: do they exist?
Contributions to nephrology 2005;149():287-94.
2004: Gert Bos; Theofanis Kanellos; Daan J A Crommelin; Wim E Hennink; Colin R Howard
Cationic polymers that enhance the performance of HbsAg DNA in vivo.
Vaccine 2004;23(4):460-9.
2004: Daan J A Crommelin
Delivery of biologicals: the wish list is long...
Expert opinion on drug delivery 2004;1(1):3-5.
2004: Natasa Jovanović; Andréanne Bouchard; Gerard W Hofland; Geert-Jan Witkamp; Daan J A Crommelin; Wim Jiskoot
Stabilization of proteins in dry powder formulations using supercritical fluid technology.
Pharmaceutical research 2004;21(11):1955-69.
2004: Arjen M Funhoff; Cornelus F van Nostrum; Martin C Lok; Marjan M Fretz; Daan J A Crommelin; Wim E Hennink
Poly(3-guanidinopropyl methacrylate): a novel cationic polymer for gene delivery.
Bioconjugate chemistry 2004;15(6):1212-20.
2004: Atthachai Homhuan; Sompol Prakongpan; Prachak Poomvises; Riks A Maas; Daan J A Crommelin; Gideon F A Kersten; Wim Jiskoot
Virosome and ISCOM vaccines against Newcastle disease: preparation, characterization and immunogenicity.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;22(5):459-68.
2004: Suzanne Hermeling; Daan J A Crommelin; Huub Schellekens; Wim Jiskoot
Structure-immunogenicity relationships of therapeutic proteins.
Pharmaceutical research 2004;21(6):897-903.
2004: Corine C Visser; L Heleen Voorwinden; Daan J A Crommelin; Meindert Danhof; Albertus G de Boer
Characterization and modulation of the transferrin receptor on brain capillary endothelial cells.
Pharmaceutical research 2004;21(5):761-9.
2004: Corine C Visser; Sanja Stevanović; L Heleen Voorwinden; Pieter J Gaillard; Daan J A Crommelin; Meindert Danhof; Albertus G de Boer
Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro.
Journal of drug targeting 2004;12(3):145-50.
2004: Diane J Burgess; Daan J A Crommelin; Ajaz Hussain; Mei-Ling Chen
Assuring quality and performance of sustained and controlled released parenterals.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(5):679-90.
2004: Diane J Burgess; Daan J A Crommelin; Ajaz Hussain; Mei-Ling Chen
Assuring quality and performance of sustained and controlled release parenterals: EUFEPS workshop report.
AAPS pharmSci 2004;6(1):E11.
2004: Bernard Metz; Gideon F A Kersten; Peter Hoogerhout; Humphrey F Brugghe; hans timmermans; Annemieke de Jong; Hugo D Meiring; Jan ten Hove; Wim E Hennink; Daan J A Crommelin; Wim Jiskoot
Identification of formaldehyde-induced modifications in proteins: reactions with model peptides.
The Journal of biological chemistry 2004;279(8):6235-43.
2004: Carmen Arigita; Joost van den Berg; Karin Wensink; Mies J van Steenbergen; Wim E Hennink; Daan J A Crommelin; Gideon F A Kersten; Wim Jiskoot
Immunogenicity of meningococcal PorA formulations encapsulated in biodegradable microspheres.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(2-3):131-41.
2004: Carmen Arigita; Wim Jiskoot; Janny Westdijk; Cor van Ingen; Wim E Hennink; Daan J A Crommelin; Gideon F A Kersten
Stability of mono- and trivalent meningococcal outer membrane vesicle vaccines.
Vaccine 2004;22(5-6):629-42.
2004: Diane J Burgess; Daan J A Crommelin; Ajaz Hussain; Mei-Ling Chen
Assuring quality and performance of sustained and controlled release parenterals: EUFEPS workshop report.
The AAPS journal 2004;6(1):100-11.
2004: Corine C Visser; L Heleen Voorwinden; Liesbeth R Harders; Mohamed Eloualid; Louis van Bloois; Daan J A Crommelin; Meindert Danhof; Albertus G de Boer
Coupling of metal containing homing devices to liposomes via a maleimide linker: use of TCEP to stabilize thiol-groups without scavenging metals.
Journal of drug targeting 2004;12(9-10):569-73.
2004: Arjen M Funhoff; Cornelus F van Nostrum; Adriënne P C A Janssen; Marcel H A M Fens; Daan J A Crommelin; Wim E Hennink
Polymer side-chain degradation as a tool to control the destabilization of polyplexes.
Pharmaceutical research 2004;21(1):170-6.
2004: Ferry J Verbaan; Christien Oussoren; Cor J Snel; Daan J A Crommelin; Wim E Hennink; Gert Storm
Steric stabilization of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes mediates prolonged circulation and tumor targeting in mice.
The journal of gene medicine 2004;6(1):64-75.
2004: Arjen M Funhoff; Cornelus F van Nostrum; Gerben A Koning; Nancy M E Schuurmans-Nieuwenbroek; Daan J A Crommelin; Wim E Hennink
Endosomal escape of polymeric gene delivery complexes is not always enhanced by polymers buffering at low pH.
Biomacromolecules 2004;5(1):32-9.
2003: Bernard Metz; Wim Jiskoot; Wim E Hennink; Daan J A Crommelin; Gideon F A Kersten
Physicochemical and immunochemical techniques predict the quality of diphtheria toxoid vaccines.
Vaccine 2003;22(2):156-67.
2003: Suzanne Hermeling; Huub Schellekens; Daan J A Crommelin; Wim Jiskoot
Micelle-associated protein in epoetin formulations: aA risk factor for immunogenicity?
Pharmaceutical research 2003;20(12):1903-7.
2003: Daan J A Crommelin; Gert Storm; Ruud Verrijk; Leo de Leede; Wim Jiskoot; Wim E Hennink
Shifting paradigms: biopharmaceuticals versus low molecular weight drugs.
International journal of pharmaceutics 2003;266(1-2):3-16.
2003: Josbert M Metselaar; Peter Bruin; Leo W T de Boer; Tom de Vringer; Cor J Snel; Christien Oussoren; Marca H M Wauben; Daan J A Crommelin; Gert Storm; Wim E Hennink
A novel family of L-amino acid-based biodegradable polymer-lipid conjugates for the development of long-circulating liposomes with effective drug-targeting capacity.
Bioconjugate chemistry 2003;14(6):1156-64.
2003: Huub Schellekens; Daan J A Crommelin
Equivocal role of micelles in Eprex adverse events.
Nature biotechnology 2003;21(11):1265; author reply 1266.
2003: Carmen Arigita; Lisette Bevaart; Linda A Everse; Gerben A Koning; Wim E Hennink; Daan J A Crommelin; Jan G J van de Winkel; Martine J van Vugt; Gideon F A Kersten; Wim Jiskoot
Liposomal meningococcal B vaccination: role of dendritic cell targeting in the development of a protective immune response.
Infection and immunity 2003;71(9):5210-8.
2003: Jordy Luten; Jan Hein van Steenis; R van Someren; Johan Kemmink; Nancy M E Schuurmans-Nieuwenbroek; Gerben A Koning; Daan J A Crommelin; Cornelus F van Nostrum; Wim E Hennink
Water-soluble biodegradable cationic polyphosphazenes for gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2003;89(3):483-97.
2003: Jan Hein van Steenis; E M van Maarseveen; Ferry J Verbaan; Ruud Verrijk; Daan J A Crommelin; Gert Storm; Wim E Hennink
Preparation and characterization of folate-targeted pEG-coated pDMAEMA-based polyplexes.
Journal of controlled release : official journal of the Controlled Release Society 2003;87(1-3):167-76.
2003: Daan J A Crommelin; Gert Storm; Wim Jiskoot; Robert Stenekes; Enrico Mastrobattista; Wim E Hennink
Nanotechnological approaches for the delivery of macromolecules.
Journal of controlled release : official journal of the Controlled Release Society 2003;87(1-3):81-8.
2003: Carmen Arigita; Gideon F A Kersten; Ton Hazendonk; Wim E Hennink; Daan J A Crommelin; Wim Jiskoot
Restored functional immunogenicity of purified meningococcal PorA by incorporation into liposomes.
Vaccine 2003;21(9-10):950-60.
2003: Gideon F A Kersten; Daan J A Crommelin
Liposomes and ISCOMs.
Vaccine 2003;21(9-10):915-20.
2003: Daan J A Crommelin; Gert Storm
Liposomes: from the bench to the bed.
Journal of liposome research 2003;13(1):33-6.
2002: M Luisa Corvo; João C S Jorge; Ron van't Hof; M E M Cruz; Daan J A Crommelin; Gert Storm
Superoxide dismutase entrapped in long-circulating liposomes: formulation design and therapeutic activity in rat adjuvant arthritis.
Biochimica et biophysica acta 2002;1564(1):227-36.
2002: Marco van de Weert; Riemke van Dijkhuizen-Radersma; Jeroen M Bezemer; Wim E Hennink; Daan J A Crommelin
Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;54(1):89-93.
2002: Marco van de Weert; Mies J van Steenbergen; Jeffrey L Cleland; Jorge Heller; Wim E Hennink; Daan J A Crommelin
Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: protein release and protein stability issues.
Journal of pharmaceutical sciences 2002;91(4):1065-74.
2002: E A A M Vernooij; J Jantina Kettenes-van den Bosch; Willy J M Underberg; Daan J A Crommelin
Chemical hydrolysis of DOTAP and DOPE in a liposomal environment.
Journal of controlled release : official journal of the Controlled Release Society 2002;79(1-3):299-303.
2002: Enrico Mastrobattista; Daan J A Crommelin; Jan Wilschut; Gert Storm
Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells.
Journal of liposome research 2002;12(1-2):57-65.
2001: Enrico Mastrobattista; Pieter Schoen; Jan Wilschut; Daan J A Crommelin; Gert Storm
Targeting influenza virosomes to ovarian carcinoma cells.
FEBS letters 2001;509(1):71-6.
2001: Marco van de Weert; P I Haris; Wim E Hennink; Daan J A Crommelin
Fourier transform infrared spectrometric analysis of protein conformation: effect of sampling method and stress factors.
Analytical biochemistry 2001;297(2):160-9.
2001: Enrico Mastrobattista; R H Kapel; M H Eggenhuisen; Paul Roholl; Daan J A Crommelin; Wim E Hennink; Gert Storm
Lipid-coated polyplexes for targeted gene delivery to ovarian carcinoma cells.
Cancer gene therapy 2001;8(6):405-13.
2001: H M Mollee; D P Steenvoorden; Tom de Vringer; Daan J A Crommelin
The influence of the incorporation of cholesterol and water on the particle size, bilayer thickness, melting behavior, and relative sucrose ester composition of reversed vesicles.
Journal of pharmaceutical sciences 2001;90(5):588-98.
2001: ML van Slooten; Otto Boerman; K Romøren; Eli Kedar; Daan J A Crommelin; Gert Storm
Liposomes as sustained release system for human interferon-gamma: biopharmaceutical aspects.
Biochimica et biophysica acta 2001;1530(2-3):134-45.
2001: Ferry J Verbaan; Christien Oussoren; I M van Dam; Y Takakura; M Hashida; Daan J A Crommelin; Wim E Hennink; Gert Storm
The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration.
International journal of pharmaceutics 2001;214(1-2):99-101.
2001: Robert Stenekes; A E Loebis; C M Fernandes; Daan J A Crommelin; Wim E Hennink
Degradable dextran microspheres for the controlled release of liposomes.
International journal of pharmaceutics 2001;214(1-2):17-20.
2000: Gert Bos; A Trullas-Jimeno; Wim Jiskoot; Daan J A Crommelin; Wim E Hennink
Sterilization of poly(dimethylamino) ethyl methacrylate-based gene transfer complexes.
International journal of pharmaceutics 2000;211(1-2):79-88.
2000: ML van Slooten; Antonie J W G Visser; A van Hoek; Gert Storm; Daan J A Crommelin; Wim Jiskoot
Conformational stability of human interferon-gamma on association with and dissociation from liposomes.
Journal of pharmaceutical sciences 2000;89(12):1605-19.
2000: Marco van de Weert; J Hoechstetter; Wim E Hennink; Daan J A Crommelin
The effect of a water/organic solvent interface on the structural stability of lysozyme.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(3):351-9.
2000: Marco van de Weert; R van 't Hof1; J van der Weerd; Ron M A Heeren; George Posthuma; Wim E Hennink; Daan J A Crommelin
Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(1):31-40.
2000: AJ van Rensen; Leonie S Taams; Mayken C Grosfeld-Stulemeyer; Willem van Eden; Daan J A Crommelin; Marca H M Wauben
Induction of T cell anergy by liposomes with incorporated major histocompatibility complex (MHC) II/peptide complexes.
Pharmaceutical research 2000;17(6):720-6.
2000: Robert Stenekes; A E Loebis; C M Fernandes; Daan J A Crommelin; Wim E Hennink
Controlled release of liposomes from biodegradable dextran microspheres: a novel delivery concept.
Pharmaceutical research 2000;17(6):690-5.
2000: Maria Luísa Corvo; Otto Boerman; Wim J G Oyen; J C Jorge; M E M Cruz; Daan J A Crommelin; Gert Storm
Subcutaneous administration of superoxide dismutase entrapped in long circulating liposomes: in vivo fate and therapeutic activity in an inflammation model.
Pharmaceutical research 2000;17(5):600-6.
2000: P van de Wetering; Nancy M E Schuurmans-Nieuwenbroek; Mies J van Steenbergen; Daan J A Crommelin; Wim E Hennink
Copolymers of 2-(dimethylamino)ethyl methacrylate with ethoxytriethylene glycol methacrylate or N-vinyl-pyrrolidone as gene transfer agents.
Journal of controlled release : official journal of the Controlled Release Society 2000;64(1-3):193-203.
2000: NJ Zuidam; George Posthuma; E T de Vries; Daan J A Crommelin; Wim E Hennink; Gert Storm
Effects of physicochemical characteristics of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes on cellular association and internalization.
Journal of drug targeting 2000;8(1):51-66.
2000: ML van Slooten; Gert Storm; A Zoephel; Zaruhi Küpcü; Otto Boerman; Daan J A Crommelin; Ernst Wagner; Ralf Kircheis
Liposomes containing interferon-gamma as adjuvant in tumor cell vaccines.
Pharmaceutical research 2000;17(1):42-8.
1999: Daan J A Crommelin; AJ van Rensen; Marca H M Wauben; Gert Storm
Liposomes in autoimmune diseases: selected applications in immunotherapy and inflammation detection.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(1-2):245-51.
1999: E A A M Vernooij; C A Gentry; J N Herron; Daan J A Crommelin; J Jantina Kettenes-van den Bosch
1H NMR quantification of poly(ethylene glycol)-phosphatidylethanolamine in phospholipid mixtures.
Pharmaceutical research 1999;16(10):1658-61.
1999: Carmen Arigita; NJ Zuidam; Daan J A Crommelin; Wim E Hennink
Association and dissociation characteristics of polymer/DNA complexes used for gene delivery.
Pharmaceutical research 1999;16(10):1534-41.
1999: JY Cherng; Herre Talsma; Daan J A Crommelin; Wim E Hennink
Long term stability of poly((2-dimethylamino)ethyl methacrylate)-based gene delivery systems.
Pharmaceutical research 1999;16(9):1417-23.
1999: JY Cherng; Nancy M E Schuurmans-Nieuwenbroek; Wim Jiskoot; Herre Talsma; NJ Zuidam; Wim E Hennink; Daan J A Crommelin
Effect of DNA topology on the transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid complexes.
Journal of controlled release : official journal of the Controlled Release Society 1999;60(2-3):343-53.
1999: Enrico Mastrobattista; Gert Storm; Louis van Bloois; R Reszka; PG Bloemen; Daan J A Crommelin; P A J Henricks
Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells.
Biochimica et biophysica acta 1999;1419(2):353-63.
1999: Maria Luísa Corvo; Otto Boerman; Wim J G Oyen; L van Bloois; M E M Cruz; Daan J A Crommelin; Gert Storm
Intravenous administration of superoxide dismutase entrapped in long circulating liposomes. II. In vivo fate in a rat model of adjuvant arthritis.
Biochimica et biophysica acta 1999;1419(2):325-34.
1999: W N van Dijk-Wolthuis; P van de Wetering; W L Hinrichs; LJ Hofmeyer; Rob M J Liskamp; Daan J A Crommelin; Wim E Hennink
A versatile method for the conjugation of proteins and peptides to poly[2-(dimethylamino)ethyl methacrylate].
Bioconjugate chemistry 1999;10(4):687-92.
1999: Robert Stenekes; O Franssen; E M van Bommel; Daan J A Crommelin; Wim E Hennink
The use of aqueous PEG/dextran phase separation for the preparation of dextran microspheres.
International journal of pharmaceutics 1999;183(1):29-32.
1999: JY Cherng; P vd Wetering; Herre Talsma; Daan J A Crommelin; Wim E Hennink
Stabilization of polymer-based gene delivery systems.
International journal of pharmaceutics 1999;183(1):25-8.
1999: JY Cherng; Herre Talsma; Ruud Verrijk; Daan J A Crommelin; Wim E Hennink
The effect of formulation parameters on the size of poly-((2-dimethylamino)ethyl methacrylate)-plasmid complexes.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1999;47(3):215-24.
1999: NS Postma; R C Hermsen; Daan J A Crommelin; Wijnand Eling; J Zuidema
Thiolated recombinant human tumor necrosis factor-alpha protects against Plasmodium berghei K173-induced experimental cerebral malaria in mice.
Antimicrobial agents and chemotherapy 1999;43(5):1027-33.
1999: EC van Winden; Daan J A Crommelin
Short term stability of freeze-dried, lyoprotected liposomes.
Journal of controlled release : official journal of the Controlled Release Society 1999;58(1):69-86.
1999: AJ van Rensen; Marca H M Wauben; Mayken C Grosfeld-Stulemeyer; Willem van Eden; Daan J A Crommelin
Liposomes with incorporated MHC class II/peptide complexes as antigen presenting vesicles for specific T cell activation.
Pharmaceutical research 1999;16(2):198-204.
1999: NS Postma; Cornelus C Hermsen; Daan J A Crommelin; J Zuidema; Wijnand Eling
Treatment with recombinant human tumour necrosis factor-alpha reduces parasitaemia and prevents Plasmodium berghei K173-induced experimental cerebral malaria in mice.
Parasitology 1999;118 ( Pt 1)():7-15.
1999: NS Postma; Daan J A Crommelin; Wijnand Eling; J Zuidema
Treatment with liposome-bound recombinant human tumor necrosis factor-alpha suppresses parasitemia and protects against Plasmodium berghei k173-induced experimental cerebral malaria in mice.
The Journal of pharmacology and experimental therapeutics 1999;288(1):114-20.
1998: FJ Koppenhagen; Zaruhi Küpcü; G Wallner; Daan J A Crommelin; Ernst Wagner; Gert Storm; Ralf Kircheis
Sustained cytokine delivery for anticancer vaccination: liposomes as alternative for gene-transfected tumor cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1881-6.
1998: FJ Koppenhagen; Antonie J W G Visser; J N Herron; Gert Storm; Daan J A Crommelin
Interaction of recombinant interleukin-2 with liposomal bilayers.
Journal of pharmaceutical sciences 1998;87(6):707-14.
1998: P van de Wetering; JY Cherng; Herre Talsma; Daan J A Crommelin; Wim E Hennink
2-(Dimethylamino)ethyl methacrylate based (co)polymers as gene transfer agents.
Journal of controlled release : official journal of the Controlled Release Society 1998;53(1-3):145-53.
1998: Robert Stenekes; O Franssen; E M van Bommel; Daan J A Crommelin; Wim E Hennink
The preparation of dextran microspheres in an all-aqueous system: effect of the formulation parameters on particle characteristics.
Pharmaceutical research 1998;15(4):557-61.
1998: Christien Oussoren; Wijnand Eling; Daan J A Crommelin; Gert Storm; J Zuidema
The influence of the route of administration and liposome composition on the potential of liposomes to protect tissue against local toxicity of two antitumor drugs.
Biochimica et biophysica acta 1998;1369(1):159-72.
1998: EC van Winden; Herre Talsma; Daan J A Crommelin
Thermal analysis of freeze-dried liposome-carbohydrate mixtures with modulated temperature differential scanning calorimetry.
Journal of pharmaceutical sciences 1998;87(2):231-7.
1998: J L Heeremans; R Prevost; H Feitsma; Cornelis Kluft; Daan J A Crommelin
Clot accumulation characteristics of plasminogen-bearing liposomes in a flow-system. Groningen Utrecht Institute for Drug Exploration.
Thrombosis and haemostasis 1998;79(1):144-9.
1997: JY Cherng; P van de Wetering; Herre Talsma; Daan J A Crommelin; Wim E Hennink
Freeze-drying of poly((2-dimethylamino)ethyl methacrylate)-based gene delivery systems.
Pharmaceutical research 1997;14(12):1838-41.
1997: W Zhang; EC van Winden; J A Bouwstra; Daan J A Crommelin
Enhanced permeability of freeze-dried liposomal bilayers upon rehydration.
Cryobiology 1997;35(3):277-89.
1997: Jean van den Elsen; L M van Unen; Louis van Bloois; M A Busquets; Wim Jiskoot; Peter Hoogerhout; J Wilting; JN Herron; Daan J A Crommelin
Thermodynamic analysis of the interaction between a bactericidal antibody and a PorA epitope of Neisseria meningitidis.
Biochemistry 1997;36(41):12583-91.
1997: Christien Oussoren; J Zuidema; Daan J A Crommelin; Gert Storm
Lymphatic uptake and biodistribution of liposomes after subcutaneous injection. II. Influence of liposomal size, lipid compostion and lipid dose.
Biochimica et biophysica acta 1997;1328(2):261-72.
1997: EC van Winden; W Zhang; Daan J A Crommelin
Effect of freezing rate on the stability of liposomes during freeze-drying and rehydration.
Pharmaceutical research 1997;14(9):1151-60.
1997: Jean van den Elsen; JN Herron; Peter Hoogerhout; Jan Poolman; Edwin Boel; Ton Logtenberg; J Wilting; Daan J A Crommelin; Jan Kroon; Piet Gros
Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins 1997;29(1):113-25.
1997: Jean van den Elsen; E van Pomeren; Jan Poolman; J Wilting; JN Herron; Daan J A Crommelin
On the interaction between a bactericidal antibody and a PorA epitope of Neisseria meningitidis in outer membrane vesicles: a competitive fluorescence polarization immunoassay.
Analytical biochemistry 1997;247(2):382-8.
1997: Gert Storm; Daan J A Crommelin
Colloidal systems for tumor targeting.
Hybridoma 1997;16(1):119-25.
1996: M H Vingerhoeds; Peter A Steerenberg; J J Hendriks; Daan J A Crommelin; Gert Storm
Targeted delivery of diphtheria toxin via immunoliposomes: efficient antitumor activity in the presence of inactivating anti-diphtheria toxin antibodies.
FEBS letters 1996;395(2-3):245-50.
1996: M H Vingerhoeds; Peter A Steerenberg; J J Hendriks; L C Dekker; Q G Van Hoesel; Daan J A Crommelin; Gert Storm
Immunoliposome-mediated targeting of doxorubicin to human ovarian carcinoma in vitro and in vivo.
British journal of cancer 1996;74(7):1023-9.
1996: Wim J G Oyen; Otto Boerman; Gert Storm; L van Bloois; EB Koenders; Daan J A Crommelin; Jos W M van der Meer; Frans H M Corstens
Labelled Stealth liposomes in experimental infection: an alternative to leukocyte scintigraphy?
Nuclear medicine communications 1996;17(9):742-8.
1996: Wim J G Oyen; Otto Boerman; Gert Storm; L van Bloois; EB Koenders; RA Claessens; R M Perenboom; Daan J A Crommelin; Jos W M van der Meer; Frans H M Corstens
Detecting infection and inflammation with technetium-99m-labeled Stealth liposomes.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(8):1392-7.
1996: JY Cherng; P van de Wetering; Herre Talsma; Daan J A Crommelin; Wim E Hennink
Effect of size and serum proteins on transfection efficiency of poly ((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles.
Pharmaceutical research 1996;13(7):1038-42.
1996: NJ Zuidam; Cees Versluis; E A Vernooy; Daan J A Crommelin
Gamma-irradiation of liposomes composed of saturated phospholipids: effect of bilayer composition, size, concentration and absorbed dose on chemical degradation and physical destabilization of liposomes.
Biochimica et biophysica acta 1996;1280(1):135-48.
1996: M H Vingerhoeds; Hidde J Haisma; S O Belliot; R H Smit; Daan J A Crommelin; Gert Storm
Immunoliposomes as enzyme-carriers (immuno-enzymosomes) for antibody-directed enzyme prodrug therapy (ADEPT): optimization of prodrug activating capacity.
Pharmaceutical research 1996;13(4):604-10.
1996: Gert Storm; Peter A Steerenberg; M Van Borssum Waalkes; Daan J A Crommelin
Effects of intraperitoneal administration of free and liposome-entrapped doxorubicin on rat peritoneal exudate cell populations.
Journal of drug targeting 1996;4(4):255-64.
1996: J L Heeremans; P Los; R Prevost; Daan J A Crommelin; Cornelis Kluft
Fibrin binding of plasminogen coated liposomes in vitro.
Thrombosis and haemostasis 1996;75(1):134-9.
1995: NJ Zuidam; H K Gouw; Y Barenholz; Daan J A Crommelin
Physical (in) stability of liposomes upon chemical hydrolysis: the role of lysophospholipids and fatty acids.
Biochimica et biophysica acta 1995;1240(1):101-10.
1995: NJ Zuidam; S S Lee; Daan J A Crommelin
Gamma-irradiation of non-frozen, frozen, and freeze-dried liposomes.
Pharmaceutical research 1995;12(11):1761-8.
1995: NJ Zuidam; Daan J A Crommelin
Chemical hydrolysis of phospholipids.
Journal of pharmaceutical sciences 1995;84(9):1113-9.
1995: Otto Boerman; Gert Storm; Wim J G Oyen; L van Bloois; Jos W M van der Meer; RA Claessens; Daan J A Crommelin; Frans H M Corstens
Sterically stabilized liposomes labeled with indium-111 to image focal infection.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(9):1639-44.
1995: J L Heeremans; R Prevost; M E A Bekkers; P Los; Jef J Emeis; Cornelis Kluft; Daan J A Crommelin
Thrombolytic treatment with tissue-type plasminogen activator (t-PA) containing liposomes in rabbits: a comparison with free t-PA.
Thrombosis and haemostasis 1995;73(3):488-94.
1995: PG Bloemen; P A J Henricks; L van Bloois; M C van den Tweel; A C Bloem; Frans P Nijkamp; Daan J A Crommelin; Gert Storm
Adhesion molecules: a new target for immunoliposome-mediated drug delivery.
FEBS letters 1995;357(2):140-4.
1995: J L Heeremans; H R Gerritsen; S P Meusen; F W Mijnheer; R S Gangaram Panday; R Prevost; Cornelis Kluft; Daan J A Crommelin
The preparation of tissue-type Plasminogen Activator (t-PA) containing liposomes: entrapment efficiency and ultracentrifugation damage.
Journal of drug targeting 1995;3(4):301-10.
1994: J H de Smidt; M Grit; Daan J A Crommelin
Dissolution kinetics of griseofulvin in mixed micellar solutions.
Journal of pharmaceutical sciences 1994;83(9):1209-12.
1994: M H Vingerhoeds; Gert Storm; Daan J A Crommelin
Immunoliposomes in vivo.
ImmunoMethods 1994;4(3):259-72.
1994: J J Bergers; Willem Den Otter; Hub F J Dullens; J W De Groot; Peter A Steerenberg; P M Filius; Daan J A Crommelin
Effect of immunomodulators on specific tumor immunity induced by liposome-encapsulated tumor-associated antigens.
International journal of cancer. Journal international du cancer 1994;56(5):721-6.
1994: Herre Talsma; Mies J van Steenbergen; J C Borchert; Daan J A Crommelin
A novel technique for the one-step preparation of liposomes and nonionic surfactant vesicles without the use of organic solvents. Liposome formation in a continuous gas stream: the 'bubble' method.
Journal of pharmaceutical sciences 1994;83(3):276-80.
1993: M H Vingerhoeds; Hidde J Haisma; M van Muijen; R B van de Rijt; Daan J A Crommelin; Gert Storm
A new application for liposomes in cancer therapy. Immunoliposomes bearing enzymes (immuno-enzymosomes) for site-specific activation of prodrugs.
FEBS letters 1993;336(3):485-90.
1993: J J Bergers; Willem Den Otter; Hub F J Dullens; C T Kerkvliet; Daan J A Crommelin
Interleukin-2-containing liposomes: interaction of interleukin-2 with liposomal bilayers and preliminary studies on application in cancer vaccines.
Pharmaceutical research 1993;10(12):1715-21.
1993: NJ Zuidam; S S Lee; Daan J A Crommelin
Sterilization of liposomes by heat treatment.
Pharmaceutical research 1993;10(11):1591-6.
1993: J J Bergers; Willem Den Otter; Hub F J Dullens; J W De Groot; Peter A Steerenberg; M W Mimpen; Daan J A Crommelin
Critical factors for liposome-incorporated tumour-associated antigens to induce protective tumour immunity to SL2 lymphoma cells in mice.
Cancer immunology, immunotherapy : CII 1993;37(4):271-9.
1993: M Grit; Daan J A Crommelin
Chemical stability of liposomes: implications for their physical stability.
Chemistry and physics of lipids 1993;64(1-3):3-18.
1993: M Grit; NJ Zuidam; Willy J M Underberg; Daan J A Crommelin
Hydrolysis of partially saturated egg phosphatidylcholine in aqueous liposome dispersions and the effect of cholesterol incorporation on hydrolysis kinetics.
The Journal of pharmacy and pharmacology 1993;45(6):490-5.
1993: J J Bergers; M H Vingerhoeds; L van Bloois; J N Herron; LH Janssen; Marcel J E Fischer; Daan J A Crommelin
The role of protein charge in protein-lipid interactions. pH-dependent changes of the electrophoretic mobility of liposomes through adsorption of water-soluble, globular proteins.
Biochemistry 1993;32(17):4641-9.
1993: M Grit; Willy J M Underberg; Daan J A Crommelin
Hydrolysis of saturated soybean phosphatidylcholine in aqueous liposome dispersions.
Journal of pharmaceutical sciences 1993;82(4):362-6.
1993: M Grit; Daan J A Crommelin
The effect of surface charge on the hydrolysis kinetics of partially hydrogenated egg phosphatidylcholine and egg phosphatidylglycerol in aqueous liposome dispersions.
Biochimica et biophysica acta 1993;1167(1):49-55.
1992: J L Heeremans; J J Kraaijenga; P Los; Cornelis Kluft; Daan J A Crommelin
Development of a procedure for coupling the homing device glu-plasminogen to liposomes.
Biochimica et biophysica acta 1992;1117(3):258-64.
1992: Jaap A Joles; N Willekes-Koolschijn; Hein A Koomans; Arie Van Tol; T Geelhoed-Mieras; Daan J A Crommelin; L Van Bloois; M Krajnc-Franken; L Cohen; M Griffioen
Subcutaneous administration of HMG-CoA reductase inhibitors in hyperlipidaemic and normal rats.
Laboratory animals 1992;26(4):269-80.
1992: F Kadir; Wijnand Eling; D Abrahams; J Zuidema; Daan J A Crommelin
Tissue reaction after intramuscular injection of liposomes in mice.
International journal of clinical pharmacology, therapy, and toxicology 1992;30(10):374-82.
1992: M Grit; Daan J A Crommelin
The effect of aging on the physical stability of liposome dispersions.
Chemistry and physics of lipids 1992;62(2):113-22.
1992: Herre Talsma; Gert S Gooris; M J v Steenbergen; M A Salomons; Joke A Bouwstra; Daan J A Crommelin
The influence of the molar ratio of cholesteryl hemisuccinate/dipalmitoylphosphatidylcholine on 'liposome' formation after lipid film hydration.
Chemistry and physics of lipids 1992;62(2):105-12.
1992: Wim Jiskoot; G van de Werken; J M Martin; B N Green; E C Beuvery; Daan J A Crommelin
Application of electrospray mass spectrometry (ES-MS) for the analysis of monoclonal antibody Fc subunits.
Pharmaceutical research 1992;9(7):945-51.
1992: Herre Talsma; Mies J van Steenbergen; Daan J A Crommelin
The cryopreservation of liposomes. 2. Effect of particle size on crystallization behavior and marker retention.
Cryobiology 1992;29(1):80-6.
1992: M E Ressing; Wim Jiskoot; Herre Talsma; C W van Ingen; E C Beuvery; Daan J A Crommelin
The influence of sucrose, dextran, and hydroxypropyl-beta-cyclodextrin as lyoprotectants for a freeze-dried mouse IgG2a monoclonal antibody (MN12).
Pharmaceutical research 1992;9(2):266-70.
1992: J J Bergers; Willem Den Otter; J W De Groot; A W De Blois; Hub F J Dullens; Peter A Steerenberg; Daan J A Crommelin
Reconstituted membranes of tumour cells (proteoliposomes) induce specific protection to murine lymphoma cells.
Cancer immunology, immunotherapy : CII 1992;34(4):233-40.
1991: Wim Jiskoot; M Bloemendal; B van Haeringen; Rienk van Grondelle; E C Beuvery; J N Herron; Daan J A Crommelin
Non-random conformation of a mouse IgG2a monoclonal antibody at low pH.
European journal of biochemistry / FEBS 1991;201(1):223-32.
1991: Herre Talsma; Mies J van Steenbergen; P J Salemink; Daan J A Crommelin
The cryopreservation of liposomes. 1. A differential scanning calorimetry study of the thermal behavior of a liposome dispersion containing mannitol during freezing/thawing.
Pharmaceutical research 1991;8(8):1021-6.
1991: Wim Jiskoot; Peter Hoogerhout; E C Beuvery; J N Herron; Daan J A Crommelin
Preparation and application of a fluorescein-labeled peptide for determining the affinity constant of a monoclonal antibody-hapten complex by fluorescence polarization.
Analytical biochemistry 1991;196(2):421-6.
1991: F G Poelma; R Breäs; J J Tukker; Daan J A Crommelin
Intestinal absorption of drugs. The influence of mixed micelles on on the disappearance kinetics of drugs from the small intestine of the rat.
The Journal of pharmacy and pharmacology 1991;43(5):317-24.
1991: Wim Jiskoot; J J Van Hertrooij; A M Hoven; J W Klein Gebbinck; T Van der Velden-de Groot; Daan J A Crommelin; E C Beuvery
Preparation of clinical grade monoclonal antibodies from serum-containing cell culture supernatants.
Journal of immunological methods 1991;138(2):273-83.
1991: Wim Jiskoot; A M Hoven; A A De Koning; M F Leerling; C H Reubsaet; Daan J A Crommelin; E C Beuvery
Purification and stabilisation of a poorly soluble mouse IgG3 monoclonal antibody.
Journal of immunological methods 1991;138(2):181-9.
1991: J H de Smidt; J C Offringa; Daan J A Crommelin
Dissolution rate of griseofulvin in bile salt solutions.
Journal of pharmaceutical sciences 1991;80(4):399-401.
1991: Gideon F A Kersten; A Spiekstra; E C Beuvery; Daan J A Crommelin
On the structure of immune-stimulating saponin-lipid complexes (iscoms).
Biochimica et biophysica acta 1991;1062(2):165-71.
1990: Wim Jiskoot; E C Beuvery; A A de Koning; J N Herron; Daan J A Crommelin
Analytical approaches to the study of monoclonal antibody stability.
Pharmaceutical research 1990;7(12):1234-41.
1990: H A Titulaer; Wijnand Eling; Daan J A Crommelin; P A Peeters; J Zuidema
The parenteral controlled release of liposome encapsulated chloroquine in mice.
The Journal of pharmacy and pharmacology 1990;42(8):529-32.
1990: Wim Jiskoot; J W Gebbinck; J J van Hertrooij; T van der Velden-de Groot; Daan J A Crommelin; E C Beuvery
A purification strategy for the production of clinical grade monoclonal antibodies.
Developments in biological standardization 1990;71():73-8.
1989: Wim Jiskoot; J J Van Hertrooij; J W Klein Gebbinck; T Van der Velden-de Groot; Daan J A Crommelin; E C Beuvery
Two-step purification of a murine monoclonal antibody intended for therapeutic application in man. Optimisation of purification conditions and scaling up.
Journal of immunological methods 1989;124(1):143-56.
1989: P A Peeters; K de Leest; Wijnand Eling; Daan J A Crommelin
Chloroquine blood levels after administration of the liposome-encapsulated drug in relation to therapy of murine malaria.
Pharmaceutical research 1989;6(9):787-93.
1989: P A Peeters; B G Brunink; Wijnand Eling; Daan J A Crommelin
Therapeutic effect of chloroquine(CQ)-containing immunoliposomes in rats infected with Plasmodium berghei parasitized mouse red blood cells: comparison with combinations of antibodies and CQ or liposomal CQ.
Biochimica et biophysica acta 1989;981(2):269-76.
1989: P A Peeters; C W Huiskamp; Wijnand Eling; Daan J A Crommelin
Chloroquine containing liposomes in the chemotherapy of murine malaria.
Parasitology 1989;98 Pt 3():381-6.
1989: F G Poelma; J J Tukker; Daan J A Crommelin
Intestinal absorption of drugs. I: The influence of taurocholate on the absorption of dantrolene in the small intestine of the rat.
Journal of pharmaceutical sciences 1989;78(4):285-9.
1988: Gert Storm; Peter A Steerenberg; M van Borssum Waalkes; F Emmen; Daan J A Crommelin
Potential pitfalls in in vitro antitumor activity testing of free and liposome-entrapped doxorubicin.
Journal of pharmaceutical sciences 1988;77(10):823-30.
1988: P A Peeters; Christien Oussoren; Wijnand Eling; Daan J A Crommelin
Immunospecific targeting of immunoliposomes, F(ab')2 and IgG to red blood cells in vivo.
Biochimica et biophysica acta 1988;943(2):137-47.
1988: Gideon F A Kersten; A M van de Put; T Teerlink; E C Beuvery; Daan J A Crommelin
Immunogenicity of liposomes and iscoms containing the major outer membrane protein of Neisseria gonorrhoeae: influence of protein content and liposomal bilayer composition.
Infection and immunity 1988;56(6):1661-4.
1988: Gert Storm; Peter A Steerenberg; F Emmen; M van Borssum Waalkes; Daan J A Crommelin
Release of doxorubicin from peritoneal macrophages exposed in vivo to doxorubicin-containing liposomes.
Biochimica et biophysica acta 1988;965(2-3):136-45.
1988: Gideon F A Kersten; T Teerlink; H J Derks; A J Verkleij; T L van Wezel; Daan J A Crommelin; E C Beuvery
Incorporation of the major outer membrane protein of Neisseria gonorrhoeae in saponin-lipid complexes (iscoms): chemical analysis, some structural features, and comparison of their immunogenicity with three other antigen delivery systems.
Infection and immunity 1988;56(2):432-8.
1987: J C Offringa; R Plekkenpol; Daan J A Crommelin
A differential scanning calorimetry study of the thermal behavior of water-dipalmitoylphosphatidylcholine mixtures at subzero temperatures: effects of water content, surface charge, and cholesterol.
Journal of pharmaceutical sciences 1987;76(10):821-4.
1987: J H de Smidt; J C Offringa; Daan J A Crommelin
Dissolution kinetics of griseofulvin in sodium dodecylsulphate solutions.
Journal of pharmaceutical sciences 1987;76(9):711-4.
1986: Wim Jiskoot; T Teerlink; M M Van Hoof; K Bartels; V Kanhai; Daan J A Crommelin; E C Beuvery
Immunogenic activity of gonococcal protein I in mice with three different lipoidal adjuvants delivered in liposomes and in complexes.
Infection and immunity 1986;54(2):333-8.
1986: J H de Smidt; J G Fokkens; H Grijseels; Daan J A Crommelin
Dissolution of theophylline monohydrate and anhydrous theophylline in buffer solutions.
Journal of pharmaceutical sciences 1986;75(5):497-501.
1985: Gert Storm; L van Bloois; M Brouwer; Daan J A Crommelin
The interaction of cytostatic drugs with adsorbents in aqueous media. The potential implications for liposome preparation.
Biochimica et biophysica acta 1985;818(3):343-51.
1984: H Grijseels; Daan J A Crommelin; C J De Blaey
Dissolution at porous interfaces VI: Multiple pore systems.
Journal of pharmaceutical sciences 1984;73(12):1771-4.