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Andrea Crosignani

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Marco Bertolotti; Andrea Crosignani; Marina Del Puppo
The use of stable and radioactive sterol tracers as a tool to investigate cholesterol degradation to bile acids in humans in vivo.
Andrea Crosignani; Mariangela Allocca; Massimo Zuin; Marina Del Puppo
Oxysterols in bile acid metabolism.
Sabine Oertelt-Prigione; Andrea Crosignani; Maurizio Gallieni; Emanuela Vassallo; Mauro Podda; Massimo Zuin
Severe hepatic encephalopathy in a patient with liver cirrhosis after administration of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy: a case report.

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All Publications

2012: Marco Bertolotti; Andrea Crosignani; Marina Del Puppo
The use of stable and radioactive sterol tracers as a tool to investigate cholesterol degradation to bile acids in humans in vivo.
Molecules (Basel, Switzerland) 2012;17(2):1939-68.
2011: Andrea Crosignani; Mariangela Allocca; Massimo Zuin; Marina Del Puppo
Oxysterols in bile acid metabolism.
Clinica chimica acta; international journal of clinical chemistry 2011;412(23-24):2037-45.
2010: Sabine Oertelt-Prigione; Andrea Crosignani; Maurizio Gallieni; Emanuela Vassallo; Mauro Podda; Massimo Zuin
Severe hepatic encephalopathy in a patient with liver cirrhosis after administration of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy: a case report.
Journal of medical case reports 2010;4():141.
2009: Massimo Zuin; Alessia Giorgini; Carlo Selmi; Pier Maria Battezzati; C A Cocchi; Andrea Crosignani; A Benetti; Pietro Invernizzi; Mauro Podda
Acute liver and renal failure during treatment with buprenorphine at therapeutic dose.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2009;41(7):e8-e10.
2008: Andrea Crosignani; Marina Del Puppo; Emma De Fabiani; Donatella Caruso; Domenico Gallisai; Maria G Mela; Maria L Melzi; Marzia Galli Kienle; Carla Colombo
Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis.
Clinica chimica acta; international journal of clinical chemistry 2008;395(1-2):84-8.
2008: Anna Benetti; Andrea Crosignani; Massimo Varenna; Cristina Squarcia Giussani; Mariangela Allocca; Massimo Zuin; Mauro Podda; Pier Maria Battezzati
Primary biliary cirrhosis is not an additional risk factor for bone loss in women receiving regular calcium and vitamin D supplementation: a controlled longitudinal study.
Journal of clinical gastroenterology 2008;42(3):306-11.
2007: Savino Bruno; Andrea Crosignani; Patrick Maisonneuve; Sonia Rossi; Enrico Silini; Mario U Mondelli
Hepatitis C virus genotype 1b as a major risk factor associated with hepatocellular carcinoma in patients with cirrhosis: a seventeen-year prospective cohort study.
Hepatology (Baltimore, Md.) 2007;46(5):1350-6.
2007: Andrea Crosignani; Marina Del Puppo; Matteo Longo; Emma De Fabiani; Donatella Caruso; Massimo Zuin; Mauro Podda; Norman B Javitt; Marzia Galli Kienle
Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease.
Clinica chimica acta; international journal of clinical chemistry 2007;382(1-2):82-8.
2007: Silvia Della Bella; Andrea Crosignani; Antonio Riva; Pietro Presicce; Anna Benetti; Renato Longhi; Mauro Podda; Maria Luisa Villa
Decrease and dysfunction of dendritic cells correlate with impaired hepatitis C virus-specific CD4+ T-cell proliferation in patients with hepatitis C virus infection.
Immunology 2007;121(2):283-92.
2007: Alberto Battezzati; Pier Maria Battezzati; Diana Costantini; Manuela Seia; Laura Zazzeron; Maria Chiara Russo; Valeria Daccò; Simona Bertoli; Andrea Crosignani; Carla Colombo
Spontaneous hypoglycemia in patients with cystic fibrosis.
European journal of endocrinology / European Federation of Endocrine Societies 2007;156(3):369-76.
2007: Mariangela Allocca; Andrea Crosignani; Angela Gritti; Anna Benetti; Massimo Zuin; Mauro Podda; Pier Maria Battezzati
Inadequate dietary intake but not renal tubular acidosis is associated with bone demineralization in primary biliary cirrhosis.
Alimentary pharmacology & therapeutics 2007;25(2):219-27.
2006: Mariangela Allocca; Andrea Crosignani; Angela Gritti; Giorgio Ghilardi; D Gobatti; D Caruso; Massimo Zuin; Mauro Podda; Pier Maria Battezzati
Hypercholesterolaemia is not associated with early atherosclerotic lesions in primary biliary cirrhosis.
Gut 2006;55(12):1795-800.
2006: Elena Lesma; Vera Grande; Anna Maria Di Giulio; Paola Castellana; Andrea Crosignani; AMILCARE CERRI; Alfredo Gorio
G protein-mediated signal transduction is affected in primary biliary cirrhosis.
Hepatology research : the official journal of the Japan Society of Hepatology 2006;35(1):45-52.
2005: Carla Colombo; Arianna Biffi; Massimo Agosti; Andrea Crosignani; Veronica Bennato; Antonio Marini
Pancreatic development in newborn guinea pigs fed intact or low-hydrolyzed protein formulas.
Journal of pediatric gastroenterology and nutrition 2005;41(5):644-9.
2005: Marina Del Puppo; Andrea Crosignani; Matteo Longo; Massimo Zuin; Mauro Podda; Giovanni Galli; Emma De Fabiani; Pierangela Ciuffreda; Enzo Santaniello; Norman B Javitt; Marzia Galli Kienle
A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis.
Clinica chimica acta; international journal of clinical chemistry 2005;355(1-2):23-31.
2004: Domenico Alvaro; Pietro Invernizzi; Paolo Onori; Antonio Franchitto; Adriano De Santis; Andrea Crosignani; Roberta Sferra; Stefano Ginanni-Corradini; Maria Grazia Mancino; Marco Maggioni; Adolfo Francesco Attili; Mauro Podda; Eugenio Gaudio
Estrogen receptors in cholangiocytes and the progression of primary biliary cirrhosis.
Journal of hepatology 2004;41(6):905-12.
2004: Pietro Invernizzi; Domenico Alvaro; Andrea Crosignani; Eugenio Gaudio; Mauro Podda
Tamoxifen in treatment of primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2004;39(4):1175-6.
2003: Carlo Selmi; Pietro Invernizzi; Pasquale Tripputi; Pier Maria Battezzati; Monica Bignotto; Massimo Zuin; Andrea Crosignani; Mauro Podda
T-cell receptor polymorphism in primary biliary cirrhosis.
Annali italiani di medicina interna : organo ufficiale della Società italiana di medicina interna 2003;18(3):149-53.
2003: Silvia Fargion; Savino Bruno; Mauro Borzio; Pier Maria Battezzati; Franco Bissoli; Roberto Ceriani; Annarosa Orlandi; Alessandra Maraschi; Alberto Chiesa; Lorenzo Morini; Anna Ludovica Fracanzani; Andrea Crosignani; Gemino Fiorelli; Mauro Podda
Sustained response to combination therapy in patients with chronic hepatitis C who failed to respond to interferon.
Journal of hepatology 2003;38(4):499-505.
2003: Pietro Invernizzi; Pier Maria Battezzati; Andrea Crosignani; Francesca Perego; Francesca Poli; Alberto Morabito; Alejandro Espadas De Arias; Mario Scalamogna; Massimo Zuin; Mauro Podda
Peculiar HLA polymorphisms in Italian patients with primary biliary cirrhosis.
Journal of hepatology 2003;38(4):401-6.
2003: Carla Colombo; Kenneth D R Setchell; Andrea Crosignani; Arianna Biffi; Nancy O'Connell; Massimo Agosti; Antonio Marini
Influence of breast feeding, and adapted and hydrolyzed formulas on biliary bile acids in newborn guinea pigs.
Biology of the neonate 2003;83(1):36-41.
2002: Carla Colombo; Pier Maria Battezzati; Andrea Crosignani; Alberto Morabito; Diana Costantini; Rita Padoan; Annamaria Giunta
Liver disease in cystic fibrosis: A prospective study on incidence, risk factors, and outcome.
Hepatology (Baltimore, Md.) 2002;36(6):1374-82.
2002: Calogero Cammà; Savino Bruno; Filippo Schepis; Oreste Lo Iacono; Pietro Andreone; Annagiulia Gramenzi; alessandra mangia; Angelo Andriulli; M Puoti; A Spadaro; Maria Antonietta Freni; Vito Di Marco; L Cino; G Saracco; A Chiesa; Andrea Crosignani; N Caporaso; Filomena Morisco; Mariagrazia Rumi; Antonio Craxì
Retreatment with interferon plus ribavirin of chronic hepatitis C non-responders to interferon monotherapy: a meta-analysis of individual patient data.
Gut 2002;51(6):864-9.
2002: Alberto Larghi; Massimo Zuin; Andrea Crosignani; Maria Lisa Ribero; Cristina Pipia; Pier Maria Battezzati; Giorgio Binelli; Francesco Donato; Alessandro R Zanetti; Mauro Podda; Alessandro Tagger
Outcome of an outbreak of acute hepatitis C among healthy volunteers participating in pharmacokinetics studies.
Hepatology (Baltimore, Md.) 2002;36(4 Pt 1):993-1000.
2002: M Longo; Andrea Crosignani; Pier Maria Battezzati; C Squarcia Giussani; Pietro Invernizzi; Massimo Zuin; Mauro Podda
Hyperlipidaemic state and cardiovascular risk in primary biliary cirrhosis.
Gut 2002;51(2):265-9.
2001: Pier Maria Battezzati; Massimo Zuin; Andrea Crosignani; Mariangela Allocca; Pietro Invernizzi; Carlo Selmi; E Villa; Mauro Podda
Ten-year combination treatment with colchicine and ursodeoxycholic acid for primary biliary cirrhosis: a double-blind, placebo-controlled trial on symptomatic patients.
Alimentary pharmacology & therapeutics 2001;15(9):1427-34.
2001: Savino Bruno; Pier Maria Battezzati; Giorgio Bellati; aldo manzin; Marco Maggioni; Andrea Crosignani; Mauro Borzio; L Solforosi; Alberto Morabito; G Ideo; Mauro Podda
Long-term beneficial effects in sustained responders to interferon-alfa therapy for chronic hepatitis C.
Journal of hepatology 2001;34(5):748-55.
2001: Pietro Invernizzi; Mauro Podda; Pier Maria Battezzati; Andrea Crosignani; Massimo Zuin; Eva Hitchman; Marco Maggioni; P L Meroni; Edward Penner; Józefa Wesierska-Gadek
Autoantibodies against nuclear pore complexes are associated with more active and severe liver disease in primary biliary cirrhosis.
Journal of hepatology 2001;34(3):366-72.
2001: Marina Del Puppo; M Galli Kienle; Andrea Crosignani; Maria Letizia Petroni; B Amati; Massimo Zuin; Mauro Podda
Cholesterol metabolism in primary biliary cirrhosis during simvastatin and UDCA administration.
Journal of lipid research 2001;42(3):437-41.
2000: Piero Luigi Almasio; A Floreani; M Chiaramonte; Giuseppa Provenzano; Pier Maria Battezzati; Andrea Crosignani; M Podda; luca todros; Floriano Rosina; Gioconda Saccoccio; Federico Manenti; G Ballardini; F P Bianchi; P J Scheuer; S E Davies; Antonio Craxì
Multicentre randomized placebo-controlled trial of ursodeoxycholic acid with or without colchicine in symptomatic primary biliary cirrhosis.
Alimentary pharmacology & therapeutics 2000;14(12):1645-52.
1999: C Colombo; Andrea Crosignani; Pier Maria Battezzati
Liver involvement in cystic fibrosis.
Journal of hepatology 1999;31(5):946-54.
1999: Carla Colombo; Andrea Crosignani; Pier Maria Battezzati; M R Castellani; S Comi; Maria L Melzi; Annamaria Giunta
Delayed intestinal visualization at hepatobiliary scintigraphy is associated with response to long-term treatment with ursodeoxycholic acid in patients with cystic fibrosis-associated liver disease.
Journal of hepatology 1999;31(4):672-7.
1999: Pietro Invernizzi; Kenneth D R Setchell; Andrea Crosignani; Pier Maria Battezzati; Alberto Larghi; N C O'Connell; Mauro Podda
Differences in the metabolism and disposition of ursodeoxycholic acid and of its taurine-conjugated species in patients with primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 1999;29(2):320-7.
1999: Andrea Crosignani; Pietro Invernizzi; R Ferrari; aldo manzin; S Bruno; Massimo Zuin; F B Bianchi; Mauro Podda
Exacerbation of chronic hepatitis D during interferon alpha administration.
Italian journal of gastroenterology and hepatology 1999;31(1):66-9.
1998: Pietro Invernizzi; Pier Maria Battezzati; Andrea Crosignani; P Zermiani; Monica Bignotto; N Del Papa; Massimo Zuin; Mauro Podda
Antibody to carbonic anhydrase II is present in primary biliary cirrhosis (PBC) irrespective of antimitochondrial antibody status.
Clinical and experimental immunology 1998;114(3):448-54.
1998: Marina Del Puppo; Marzia Galli Kienle; Maria Letizia Petroni; Andrea Crosignani; Mauro Podda
Serum 27-hydroxycholesterol in patients with primary biliary cirrhosis suggests alteration of cholesterol catabolism to bile acids via the acidic pathway.
Journal of lipid research 1998;39(12):2477-82.
1998: Andrea Crosignani; gabriele budillon; Lucia Cimino; Camillo del Vecchio-Blanco; Carmela Loguercio; G Ideo; G Raimondo; R Stabilini; Mauro Podda
Tauroursodeoxycholic acid for the treatment of HCV-related chronic hepatitis: a multicenter placebo-controlled study.
Hepato-gastroenterology 1998;45(23):1624-9.
1998: Marco Gardinali; L Conciato; C Cafaro; Andrea Crosignani; Pier Maria Battezzati; Angelo Agostoni; M Podda
Complement system is not activated in primary biliary cirrhosis.
Clinical immunology and immunopathology 1998;87(3):297-303.
1998: Alberto Larghi; Alessandro Tagger; Andrea Crosignani; Maria Lisa Ribero; S Bruno; Giorgio Portera; Pier Maria Battezzati; Marco Maggioni; M Fasola; Massimo Zuin; Mauro Podda
Clinical significance of hepatic HCV RNA in patients with chronic hepatitis C demonstrating long-term sustained response to interferon-alpha therapy.
Journal of medical virology 1998;55(1):7-11.
1997: Pietro Invernizzi; Andrea Crosignani; Pier Maria Battezzati; G Covini; G De Valle; Alberto Larghi; Massimo Zuin; M Podda
Comparison of the clinical features and clinical course of antimitochondrial antibody-positive and -negative primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 1997;25(5):1090-5.
1997: Alberto Larghi; Andrea Crosignani; Pier Maria Battezzati; G De Valle; Mariangela Allocca; Pietro Invernizzi; Massimo Zuin; Mauro Podda
Ursodeoxycholic and tauro-ursodeoxycholic acids for the treatment of primary biliary cirrhosis: a pilot crossover study.
Alimentary pharmacology & therapeutics 1997;11(2):409-14.
1997: Savino Bruno; Enrico Silini; Andrea Crosignani; Franco Borzio; Gioacchino Leandro; F Bono; M Asti; S Rossi; Alberto Larghi; Antonella Cerino; Mauro Podda; Mario U Mondelli
Hepatitis C virus genotypes and risk of hepatocellular carcinoma in cirrhosis: a prospective study.
Hepatology (Baltimore, Md.) 1997;25(3):754-8.
1997: S Bruno; aldo manzin; Massimo Roncalli; Maria Letizia Petroni; S Rossi; M Pedicino; Alberto Larghi; Andrea Crosignani; Mauro Podda
Histological changes but not virus eradication reflect biochemical improvement in chronic hepatitis C patients showing a long-term response to interferon alpha therapy.
Italian journal of gastroenterology and hepatology 1997;29(1):31-7.
1996: Andrea Crosignani; Kenneth D R Setchell; Pietro Invernizzi; Alberto Larghi; Cecília M P Rodrigues; Mauro Podda
Clinical pharmacokinetics of therapeutic bile acids.
Clinical pharmacokinetics 1996;30(5):333-58.
1996: Mario Fracchia; K D Setchell; Andrea Crosignani; Mauro Podda; N O'Connell; Roberto Ferraris; A F Hofmann; Giovanni Galatola
Bile acid conjugation in early stage cholestatic liver disease before and during treatment with ursodeoxycholic acid.
Clinica chimica acta; international journal of clinical chemistry 1996;248(2):175-85.
1996: Andrea Crosignani; Pier Maria Battezzati; Kenneth D R Setchell; Pietro Invernizzi; G Covini; Massimo Zuin; Mauro Podda
Tauroursodeoxycholic acid for treatment of primary biliary cirrhosis. A dose-response study.
Digestive diseases and sciences 1996;41(4):809-15.
1996: Kenneth D R Setchell; Cecília M P Rodrigues; Mauro Podda; Andrea Crosignani
Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis.
Gut 1996;38(3):439-46.
1996: Mauro Podda; Andrea Crosignani; Pier Maria Battezzati; M Quagliuolo; C Valsania; Pietro Invernizzi; Massimo Zuin
Ursodeoxycholic acid therapy in primary biliary cirrhosis.
The Italian journal of gastroenterology 1996;28(2):114-7.
1995: Bianca Marasini; C Pipia; G DeValle; Andrea Crosignani; L Petroni; Massimo Cugno; S Zeni; Savino Bruno; C Bassani
Vascular impairment in patients with primary biliary cirrhosis.
International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation 1995;15(2):75-9.
1994: M Camisasca; Andrea Crosignani; Pier Maria Battezzati; walter albisetti; G Grandinetti; L Pietrogrande; A Biffi; Massimo Zuin; Mauro Podda
Parenteral calcitonin for metabolic bone disease associated with primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 1994;20(3):633-7.
1994: C Colombo; Andrea Crosignani; M G Apostolo; M T Marzano; N Bettinardi; Annamaria Giunta
Oral bile acids in cystic fibrosis-associated liver disease.
Journal of the Royal Society of Medicine 1994;87 Suppl 21():20-4.
1993: Stefano Bellentani; Mauro Podda; Claudio Tiribelli; F Callea; M Marazzi; M Sodde; R Merlini; P M Batezzati; Andrea Crosignani; Massimo Zuin
Ursodiol in the long-term treatment of chronic hepatitis: a double-blind multicenter clinical trial.
Journal of hepatology 1993;19(3):459-64.
1992: Pier Maria Battezzati; Mauro Podda; Savino Bruno; Massimo Zuin; Andrea Crosignani; M Camisasca; A Chiesa; Maria Letizia Petroni; A Russo; P Gallotti
Factors predicting early response to treatment with recombinant interferon alpha-2a in chronic non-A, non-B hepatitis. Preliminary report of a long-term trial.
The Italian journal of gastroenterology 1992;24(9):481-4.
1992: C Colombo; Andrea Crosignani; M Assaisso; Pier Maria Battezzati; Mauro Podda; Annamaria Giunta; Linda Zimmer-Nechemias; Kenneth D R Setchell
Ursodeoxycholic acid therapy in cystic fibrosis-associated liver disease: a dose-response study.
Hepatology (Baltimore, Md.) 1992;16(4):924-30.
1992: E Bertolini; Pier Maria Battezzati; P Zermiani; Savino Bruno; G A Moroni; F Marelli; Erica Villa; F Manenti; Massimo Zuin; Andrea Crosignani
Hepatitis C virus testing in primary biliary cirrhosis.
Journal of hepatology 1992;15(1-2):207-10.
1991: Andrea Crosignani; Mauro Podda; Pier Maria Battezzati; E Bertolini; Massimo Zuin; D Watson; Kenneth D R Setchell
Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration.
Hepatology (Baltimore, Md.) 1991;14(6):1000-7.
1991: Andrea Crosignani; Mauro Podda; E Bertolini; Pier Maria Battezzati; Massimo Zuin; Kenneth D R Setchell
Failure of ursodeoxycholic acid to prevent a cholestatic episode in a patient with benign recurrent intrahepatic cholestasis: a study of bile acid metabolism.
Hepatology (Baltimore, Md.) 1991;13(6):1076-83.
1991: Massimo Zuin; Maria Letizia Petroni; G Grandinetti; Andrea Crosignani; E Bertolini; Pier Maria Battezzati; Mauro Podda
Comparison of effects of chenodeoxycholic and ursodeoxycholic acid and their combination on biliary lipids in obese patients with gallstones.
Scandinavian journal of gastroenterology 1991;26(3):257-62.
1991: Andrea Crosignani; Pier Maria Battezzati; Kenneth D R Setchell; M Camisasca; E Bertolini; A Roda; Massimo Zuin; Mauro Podda
Effects of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis: a dose-response study.
Hepatology (Baltimore, Md.) 1991;13(2):339-44.
1990: C Colombo; Kenneth D R Setchell; Mauro Podda; Andrea Crosignani; A Roda; L Curcio; M Ronchi; Annamaria Giunta
Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis.
The Journal of pediatrics 1990;117(3):482-9.
1990: Mauro Podda; C Ghezzi; Pier Maria Battezzati; Andrea Crosignani; Massimo Zuin; A Roda
Effects of ursodeoxycholic acid and taurine on serum liver enzymes and bile acids in chronic hepatitis.
Gastroenterology 1990;98(4):1044-50.
1990: C Colombo; Pier Maria Battezzati; Andrea Crosignani; M Assaisso; M Ronchi; Annamaria Giunta
Effects of taurine and ursodeoxycholic acid on liver function tests in patients with cystic fibrosis.
Acta Universitatis Carolinae. Medica 1990;36(1-4):148-51.
1989: Mauro Podda; C Ghezzi; Pier Maria Battezzati; E Bertolini; Andrea Crosignani; Maria Letizia Petroni; Massimo Zuin
Effect of different doses of ursodeoxycholic acid in chronic liver disease.
Digestive diseases and sciences 1989;34(12 Suppl):59S-65S.
1988: Mauro Podda; C Ghezzi; Pier Maria Battezzati; E Bertolini; Andrea Crosignani; Maria Letizia Petroni; Massimo Zuin
Ursodeoxycholic acid for chronic liver diseases.
Journal of clinical gastroenterology 1988;10 Suppl 2():S25-31.