Nicholas Cross

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Kreil Sebastian; Hochhaus Andreas; Cross Nicholas C P; Chase Andrew
A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias.
Sorour Youssef; Dalley Christopher D; Snowden John A; Cross Nicholas C P; Reilly John T
Acute myeloid leukaemia with associated eosinophilia: justification for FIP1L1-PDGFRA screening in cases lacking the CBFB-MYH11 fusion gene.
Chiecchio Laura; Dagrada Gian Paolo; Protheroe Rebecca K M; Stockley David M; Smith Alastair G; Orchard Kim H; Cross Nicholas C P; Harrison Christine J; Ross Fiona M;
Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case.

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All Publications

2009: Kreil Sebastian; Hochhaus Andreas; Cross Nicholas C P; Chase Andrew
A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias.
Leukemia research 2009;33(9):e168-9.
2009: Sorour Youssef; Dalley Christopher D; Snowden John A; Cross Nicholas C P; Reilly John T
Acute myeloid leukaemia with associated eosinophilia: justification for FIP1L1-PDGFRA screening in cases lacking the CBFB-MYH11 fusion gene.
British journal of haematology 2009;146(2):225-7.
2009: Chiecchio Laura; Dagrada Gian Paolo; Protheroe Rebecca K M; Stockley David M; Smith Alastair G; Orchard Kim H; Cross Nicholas C P; Harrison Christine J; Ross Fiona M;
Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case.
Haematologica 2009;94(7):1024-8.
2009: Chiecchio Laura; Dagrada Gian Paolo; White Helen E; Towsend Mark R; Protheroe Rebecca K M; Cheung Kan Luk; Stockley David M; Orchard Kim H; Cross Nicholas C P; Harrison Christine J; Ross Fiona M;
Frequent upregulation of MYC in plasma cell leukemia.
Genes, chromosomes & cancer 2009;48(7):624-36.
2009: Grand Francis H; Hidalgo-Curtis Claire E; Ernst Thomas; Zoi Katerina; Zoi Christine; McGuire Carolann; Kreil Sebastian; Jones Amy; Score Joannah; Metzgeroth Georgia; Oscier David; Hall Andrew; Brandts Christian; Serve Hubert; Reiter Andreas; Chase Andrew J; Cross Nicholas C P
Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms.
Blood 2009;113(24):6182-92.
2009: Jones Amy V; Chase Andrew; Silver Richard T; Oscier David; Zoi Katerina; Wang Y Lynn; Cario Holger; Pahl Heike L; Collins Andrew; Reiter Andreas; Grand Francis; Cross Nicholas C P
JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms.
Nature genetics 2009;41(4):446-9.
2009: Beer Philip A; Jones Amy V; Bench Anthony J; Goday-Fernandez Andrea; Boyd Elaine M; Vaghela Krishna J; Erber Wendy N; Odeh Bassam; Wright Christine; McMullin Mary Frances; Cullis Jonathan; Huntly Brian J P; Harrison Claire N; Cross Nicholas C P; Green Anthony R
Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones.
British journal of haematology 2009;144(6):904-8.
2009: Dahabreh Issa J; Jones Amy V; Voulgarelis Michael; Giannouli Stavroula; Zoi Christine; Alafakis-Tzannatos Christina; Varla-Leftherioti Marighoula; Moutsopoulos Haralampos M; Loukopoulos Dimitris; Fotiou Stelios; Cross Nicholas C P; Zoi Katerina
No evidence for increased prevalence of JAK2 V617F in women with a history of recurrent miscarriage.
British journal of haematology 2009;144(5):802-3.
2009: Walz C; Score J; Mix J; Cilloni D; Roche-Lestienne C; Yeh R-F; Wiemels J L; Ottaviani E; Erben P; Hochhaus A; Baccarani M; Grimwade D; Preudhomme C; Apperley J; Martinelli G; Saglio G; Cross N C P; Reiter A;
The molecular anatomy of the FIP1L1-PDGFRA fusion gene.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(2):271-8.
2009: Score J; Walz C; Jovanovic J V; Jones A V; Waghorn K; Hidalgo-Curtis C; Lin F; Grimwade D; Grand F; Reiter A; Cross N C P
Detection and molecular monitoring of FIP1L1-PDGFRA-positive disease by analysis of patient-specific genomic DNA fusion junctions.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(2):332-9.
2009: Chase A; Schultheis B; Kreil S; Baxter J; Hidalgo-Curtis C; Jones A; Zhang L; Grand F H; Melo J V; Cross N C P
Imatinib sensitivity as a consequence of a CSF1R-Y571D mutation and CSF1/CSF1R signaling abnormalities in the cell line GDM1.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(2):358-64.
2008: Metzgeroth Georgia; Walz Christoph; Erben Philipp; Popp Helena; Schmitt-Graeff Annette; Haferlach Claudia; Fabarius Alice; Schnittger Susanne; Grimwade David; Cross Nicholas C P; Hehlmann Rüdiger; Hochhaus Andreas; Reiter Andreas
Safety and efficacy of imatinib in chronic eosinophilic leukaemia and hypereosinophilic syndrome: a phase-II study.
British journal of haematology 2008;143(5):707-15.
2008: Jones Amy V; Cross Nicholas C P; White Helen E; Green Anthony R; Scott Linda M
Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis.
Haematologica 2008;93(10):1560-4.
2008: Branford Susan; Fletcher Linda; Cross Nicholas C P; Müller Martin C; Hochhaus Andreas; Kim Dong-Wook; Radich Jerald P; Saglio Giuseppe; Pane Fabrizio; Kamel-Reid Suzanne; Wang Y Lynn; Press Richard D; Lynch Kevin; Rudzki Zbigniew; Goldman John M; Hughes Timothy
Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials.
Blood 2008;112(8):3330-8.
2008: Huang Kuan-Po; Chase Andrew J; Cross Nicholas C P; Reiter Andrea; Li Tzu-Ying; Wang Tso-Fu; Chu Sung-Chao; Lu Xuan-Yin; Li Chi-Cheng; Kao Ruey-Ho
Evolutional change of karyotype with t(8;9)(p22;p24) and HLA-DR immunophenotype in relapsed acute myeloid leukemia.
International journal of hematology 2008;88(2):197-201.
2008: Cross Nicholas C P
Hitchhikers' guide to the leukemia genome.
Blood 2008;111(9):4428-9.
2008: Hidalgo-Curtis Claire; Chase Andrew; Drachenberg Milton; Roberts Mark W; Finkelstein Jerry Z; Mould Sarah; Oscier David; Cross Nicholas C P; Grand Francis H
The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1.
Genes, chromosomes & cancer 2008;47(5):379-85.
2008: Cross Nicholas C P; Hughes Timothy P; Hochhaus Andreas; Goldman John M
International standardisation of quantitative real-time RT-PCR for BCR-ABL.
Leukemia research 2008;32(3):505-6.
2008: Cross Nicholas C P; Reiter Andreas
Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders.
Acta haematologica 2008;119(4):199-206.
2007: Burgstaller S; Kreil S; Waghorn K; Metzgeroth G; Preudhomme C; Zoi K; White H; Cilloni D; Zoi C; Brito-Babapulle F; Walz C; Reiter A; Cross N C P
The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(12):2428-32.
2007: Jones A V; Bunyan D J; Cross N C P
No evidence for amplification of V617F JAK2 in myeloproliferative disorders.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(12):2561-3.
2007: White Helen E; Hall Victoria J; Cross Nicholas C P
Methylation-sensitive high-resolution melting-curve analysis of the SNRPN gene as a diagnostic screen for Prader-Willi and Angelman syndromes.
Clinical chemistry 2007;53(11):1960-2.
2007: Grand Francis H; Iqbal Sameena; Zhang Lingyan; Russell Nigel H; Chase Andrew; Cross Nicholas C P
A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy.
Experimental hematology 2007;35(11):1723-7.
2007: Chase Andrew; Grand Francis H; Cross Nicholas C P
Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome.
Blood 2007;110(10):3729-34.
2007: Jenner Matthew W; Leone Paola E; Walker Brian A; Ross Fiona M; Johnson David C; Gonzalez David; Chiecchio Laura; Dachs Cabanas Elisabet; Dagrada Gian Paolo; Nightingale Mathew; Protheroe Rebecca K M; Stockley David; Else Monica; Dickens Nicholas J; Cross Nicholas C P; Davies Faith E; Morgan Gareth J
Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma.
Blood 2007;110(9):3291-300.
2007: Reiter Andreas; Grimwade David; Cross Nicholas C P
Diagnostic and therapeutic management of eosinophilia-associated chronic myeloproliferative disorders.
Haematologica 2007;92(9):1153-8.
2007: Curtis C E; Grand F H; Waghorn K; Sahoo T P; George J; Cross N C P
A novel ETV6-PDGFRB fusion transcript missed by standard screening in a patient with an imatinib responsive chronic myeloproliferative disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(8):1839-41.
2007: Kreil Sebastian; Pfirrmann Markus; Haferlach Claudia; Waghorn Katherine; Chase Andrew; Hehlmann Rüdiger; Reiter Andreas; Hochhaus Andreas; Cross Nicholas C P;
Heterogeneous prognostic impact of derivative chromosome 9 deletions in chronic myelogenous leukemia.
Blood 2007;110(4):1283-90.
2007: Krämer Alwin; Reiter Andreas; Kruth Jens; Erben Philipp; Hochhaus Andreas; Müller Martin; Cross Nicholas C P; Jones Amy V; Ho Anthony D; Hensel Manfred
JAK2-V617F mutation in a patient with Philadelphia-chromosome-positive chronic myeloid leukaemia.
The lancet oncology 2007;8(7):658-60.
2007: Curtis Claire E; Grand Francis H; Musto Pellegrino; Clark Andrew; Murphy John; Perla Gianni; Minervini Maria M; Stewart Janet; Reiter Andreas; Cross Nicholas C P
Two novel imatinib-responsive PDGFRA fusion genes in chronic eosinophilic leukaemia.
British journal of haematology 2007;138(1):77-81.
2007: Mughal T; Cortes J; Cross N C P; Donato N; Hantschel O; Jabbour E; Kantarjian H; Melo J V; Skorski T; Silver R T; Goldman J M
Chronic myeloid leukemia--some topical issues.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(7):1347-52.
2007: Metzgeroth G; Walz C; Score J; Siebert R; Schnittger S; Haferlach C; Popp H; Haferlach T; Erben P; Mix J; Müller M C; Beneke H; Müller L; Del Valle F; Aulitzky W E; Wittkowsky G; Schmitz N; Schulte C; Müller-Hermelink K; Hodges E; Whittaker S J; Diecker F; Döhner H; Schuld P; Hehlmann R; Hochhaus A; Cross N C P; Reiter A
Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(6):1183-8.
2007: Jovanovic Jelena V; Score Joannah; Waghorn Katherine; Cilloni Daniela; Gottardi Enrico; Metzgeroth Georgia; Erben Philipp; Popp Helena; Walz Christoph; Hochhaus Andreas; Roche-Lestienne Catherine; Preudhomme Claude; Solomon Ellen; Apperley Jane; Rondoni Michela; Ottaviani Emanuela; Martinelli Giovanni; Brito-Babapulle Finella; Saglio Giuseppe; Hehlmann Rüdiger; Cross Nicholas C P; Reiter Andreas; Grimwade David
Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.
Blood 2007;109(11):4635-40.
2007: Chen Qiaofang; Lu Pin; Jones Amy V; Cross Nicholas C P; Silver Richard T; Wang Y Lynn
Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders.
The Journal of molecular diagnostics : JMD 2007;9(2):272-6.
2007: Crescenzi B; Chase A; Starza R La; Beacci D; Rosti V; Gallì A; Specchia G; Martelli M F; Vandenberghe P; Cools J; Jones A V; Cross N C P; Marynen P; Mecucci C
FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(3):397-402.
2007: Bunyan David J; Skinner Alison C; Ashton Emma J; Sillibourne Julie; Brown Tom; Collins Amanda L; Cross Nicholas C P; Harvey John F; Robinson David O
Simultaneous MLPA-based multiplex point mutation and deletion analysis of the dystrophin gene.
Molecular biotechnology 2007;35(2):135-40.
2007: Reiter Andreas; Walz Christoph; Cross Nicholas C P
Tyrosine kinases as therapeutic targets in BCR-ABL negative chronic myeloproliferative disorders.
Current drug targets 2007;8(2):205-16.
2007: Walz Christoph; Metzgeroth Georgia; Haferlach Claudia; Schmitt-Graeff Annette; Fabarius Alice; Hagen Volker; Prümmer Otto; Rauh Stefan; Hehlmann Rüdiger; Hochhaus Andreas; Cross Nicholas C P; Reiter Andreas
Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene.
Haematologica 2007;92(2):163-9.
2007: David Marianna; Cross Nicholas C P; Burgstaller Sonja; Chase Andrew; Curtis Claire; Dang Raymond; Gardembas Martine; Goldman John M; Grand Francis; Hughes George; Huguet Francoise; Lavender Louise; McArthur Grant A; Mahon Francois X; Massimini Giorgio; Melo Junia; Rousselot Philippe; Russell-Jones Robin J; Seymour John F; Smith Graeme; Stark Alastair; Waghorn Katherine; Nikolova Zariana; Apperley Jane F
Durable responses to imatinib in patients with PDGFRB fusion gene-positive and BCR-ABL-negative chronic myeloproliferative disorders.
Blood 2007;109(1):61-4.
2007: Wang Y Lynn; Lee Joong W; Kui Jonathan S; Chadburn Amy; Cross Nicholas C P; Knowles Daniel M; Coleman Morton
Evaluation of JAK2 in B and T cell neoplasms: identification of JAK2(V617F) mutation of undetermined significance (JMUS) in the bone marrow of three individuals.
Acta haematologica 2007;118(4):209-14.
2006: Verstovsek S; Silver R T; Cross N C P; Tefferi A
JAK2V617F mutational frequency in polycythemia vera: 100%, >90%, less?
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(11):2067.
2006: Branford S; Cross N C P; Hochhaus A; Radich J; Saglio G; Kaeda J; Goldman J; Hughes T
Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(11):1925-30.
2006: Zhang Ling-Yan; Xu Gong-Li; Cross Nicholas C P
[Application of denaturing high performance liquid chromatography to mutation detection of the c-kit gene in mastocytosis]
Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2006;14(5):981-4.
2006: Chase Andrew; Cross Nicholas C P
Signal transduction therapy in haematological malignancies: identification and targeting of tyrosine kinases.
Clinical science (London, England : 1979) 2006;111(4):233-49.
2006: Walz Christoph; Curtis Claire; Schnittger Susanne; Schultheis Beate; Metzgeroth Georgia; Schoch Claudia; Lengfelder Eva; Erben Philipp; Müller Martin C; Haferlach Torsten; Hochhaus Andreas; Hehlmann Rüdiger; Cross Nicholas C P; Reiter Andreas
Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene.
Genes, chromosomes & cancer 2006;45(10):950-6.
2006: Chiecchio L; Protheroe R K M; Ibrahim A H; Cheung K L; Rudduck C; Dagrada G P; Cabanas E D; Parker T; Nightingale M; Wechalekar A; Orchard K H; Harrison C J; Cross N C P; Morgan G J; Ross F M
Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(9):1610-7.
2006: Tefferi Ayalew; Barosi Giovanni; Mesa Ruben A; Cervantes Francisco; Deeg H Joachim; Reilly John T; Verstovsek Srdan; Dupriez Brigitte; Silver Richard T; Odenike Olatoyosi; Cortes Jorge; Wadleigh Martha; Solberg Lawrence A; Camoriano John K; Gisslinger Heinz; Noel Pierre; Thiele Juergen; Vardiman James W; Hoffman Ronald; Cross Nicholas C P; Gilliland D Gary; Kantarjian Hagop;
International Working Group (IWG) consensus criteria for treatment response in myelofibrosis with myeloid metaplasia, for the IWG for Myelofibrosis Research and Treatment (IWG-MRT).
Blood 2006;108(5):1497-503.
2006: Hughes Timothy; Deininger Michael; Hochhaus Andreas; Branford Susan; Radich Jerald; Kaeda Jaspal; Baccarani Michele; Cortes Jorge; Cross Nicholas C P; Druker Brian J; Gabert Jean; Grimwade David; Hehlmann Rüdiger; Kamel-Reid Suzanne; Lipton Jeffrey H; Longtine Janina; Martinelli Giovanni; Saglio Giuseppe; Soverini Simona; Stock Wendy; Goldman John M
Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results.
Blood 2006;108(1):28-37.
2006: White Helen E; Durston Victoria J; Harvey John F; Cross Nicholas C P
Quantitative analysis of SNRPN(correction of SRNPN) gene methylation by pyrosequencing as a diagnostic test for Prader-Willi syndrome and Angelman syndrome.
Clinical chemistry 2006;52(6):1005-13.
2006: Score J; Curtis C; Waghorn K; Stalder M; Jotterand M; Grand F H; Cross N C P
Identification of a novel imatinib responsive KIF5B-PDGFRA fusion gene following screening for PDGFRA overexpression in patients with hypereosinophilia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(5):827-32.
2006: Kaeda Jaspal; O'Shea Derville; Szydlo Richard M; Olavarria Eduardo; Dazzi Francesco; Marin David; Saunders Susan; Khorashad Jamshid S; Cross Nicholas C P; Goldman John M; Apperley Jane F
Serial measurement of BCR-ABL transcripts in the peripheral blood after allogeneic stem cell transplantation for chronic myeloid leukemia: an attempt to define patients who may not require further therapy.
Blood 2006;107(10):4171-6.
2006: Jones Amy V; Silver Richard T; Waghorn Katherine; Curtis Claire; Kreil Sebastian; Zoi Katerina; Hochhaus Andreas; Oscier David; Metzgeroth Georgia; Lengfelder Eva; Reiter Andreas; Chase Andrew J; Cross Nicholas C P
Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha.
Blood 2006;107(8):3339-41.
2006: Zhang Ling Yan; Smith Matthew L; Schultheis Beate; Fitzgibbon Jude; Lister T Andrew; Melo Junia V; Cross Nicholas C P; Cavenagh Jamie D
A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy.
Leukemia research 2006;30(4):373-8.
2006: Vizmanos J L; Ormazábal C; Larráyoz M J; Cross N C P; Calasanz M J
JAK2 V617F mutation in classic chronic myeloproliferative diseases: a report on a series of 349 patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(3):534-5.
2006: Chung K F; Hew M; Score J; Jones A V; Reiter A; Cross N C P; Bain B J
Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;27(1):230-2.
2006: Gotlib Jason; Cross N C P; Gilliland D Gary
Eosinophilic disorders: molecular pathogenesis, new classification, and modern therapy.
Best practice & research. Clinical haematology 2006;19(3):535-69.
2005: Rives Susana; Alcorta Iñaki; Toll Teresa; Tuset Esperanza; Estella Jesús; Cross Nicholas C P
Idiopathic hypereosinophilic syndrome in children: report of a 7-year-old boy with FIP1L1-PDGFRA rearrangement.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2005;27(12):663-5.
2005: Mc Lornan Donald P; Percy Melanie J; Jones Amy V; Cross Nicholas C P; Mc Mullin Mary Frances
Chronic neutrophilic leukemia with an associated V617F JAK2 tyrosine kinase mutation.
Haematologica 2005;90(12):1696-7.
2005: Grand Francis H; Koduru Prasad; Cross Nicholas C P; Allen Steven L
NUP98-LEDGF fusion and t(9;11) in transformed chronic myeloid leukemia.
Leukemia research 2005;29(12):1469-72.
2005: Ross F M; Ibrahim A H; Vilain-Holmes A; Winfield M O; Chiecchio L; Protheroe R K M; Strike P; Gunasekera J L; Jones A; Harrison C J; Morgan G J; Cross N C P;
Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(9):1634-42.
2005: Jones Amy V; Kreil Sebastian; Zoi Katerina; Waghorn Katherine; Curtis Claire; Zhang Lingyan; Score Joannah; Seear Rachel; Chase Andrew J; Grand Francis H; White Helen; Zoi Christine; Loukopoulos Dimitris; Terpos Evangelos; Vervessou Elisavet-Christine; Schultheis Beate; Emig Michael; Ernst Thomas; Lengfelder Eva; Hehlmann Rüdiger; Hochhaus Andreas; Oscier David; Silver Richard T; Reiter Andreas; Cross Nicholas C P
Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders.
Blood 2005;106(6):2162-8.
2005: Dingli David; Grand Francis H; Mahaffey Victor; Spurbeck Jack; Ross Fiona M; Watmore Ann E; Reilly John T; Cross Nicholas C P; Dewald Gordon W; Tefferi Ayalew
Der(6)t(1;6)(q21-23;p21.3): a specific cytogenetic abnormality in myelofibrosis with myeloid metaplasia.
British journal of haematology 2005;130(2):229-32.
2005: Walz C; Chase A; Schoch C; Weisser A; Schlegel F; Hochhaus A; Fuchs R; Schmitt-Gräff A; Hehlmann R; Cross N C P; Reiter A
The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(6):1005-9.
2005: Meyer-Monard S; Mühlematter D; Streit A; Chase A J; Gratwohl A; Cross N C P; Jotterand M; Tichelli A
Broad molecular screening of an unclassifiable myeloproliferative disorder reveals an unexpected ETV6/ABL1 fusion transcript.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(6):1096-9.
2005: Mistry Anita R; Felix Carolyn A; Whitmarsh Ryan J; Mason Annabel; Reiter Andreas; Cassinat Bruno; Parry Anne; Walz Christoph; Wiemels Joseph L; Segal Mark R; Adès Lionel; Blair Ian A; Osheroff Neil; Peniket Andrew J; Lafage-Pochitaloff Marina; Cross Nicholas C P; Chomienne Christine; Solomon Ellen; Fenaux Pierre; Grimwade David
DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
The New England journal of medicine 2005;352(15):1529-38.
2005: Reiter Andreas; Walz Christoph; Watmore Ann; Schoch Claudia; Blau Ilona; Schlegelberger Brigitte; Berger Ute; Telford Nick; Aruliah Shilani; Yin John A; Vanstraelen Danny; Barker Helen F; Taylor Peter C; O'Driscoll Aisling; Benedetti Fabio; Rudolph Cornelia; Kolb Hans-Jochem; Hochhaus Andreas; Hehlmann Rüdiger; Chase Andrew; Cross Nicholas C P
The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2.
Cancer research 2005;65(7):2662-7.
2005: Slade Martin J; Singh Anjana; Smith Brendan M; Tripuraneni Gopi; Hall Emma; Peckitt Clare; Fox Samantha; Graham Helen; Lüchtenborg Margreet; Sinnett H Dudley; Cross Nicholas C P; Coombes R Charles
Persistence of bone marrow micrometastases in patients receiving adjuvant therapy for breast cancer: results at 4 years.
International journal of cancer. Journal international du cancer 2005;114(1):94-100.
2005: Odero M D; Grand F H; Iqbal S; Ross F; Roman J P; Vizmanos J L; Andrieux J; Laï J L; Calasanz M J; Cross N C P
Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(2):245-52.
2005: White Helen E; Durston Victoria J; Seller Anneke; Fratter Carl; Harvey John F; Cross Nicholas C P
Accurate detection and quantitation of heteroplasmic mitochondrial point mutations by pyrosequencing.
Genetic testing 2005;9(3):190-9.
2004: Jones A V; Cross N C P
Oncogenic derivatives of platelet-derived growth factor receptors.
Cellular and molecular life sciences : CMLS 2004;61(23):2912-23.
2004: Grand Francis H; Burgstaller Sonja; Kühr Thomas; Baxter E Joanna; Webersinke Gerald; Thaler Josef; Chase Andrew J; Cross Nicholas C P
p53-Binding protein 1 is fused to the platelet-derived growth factor receptor beta in a patient with a t(5;15)(q33;q22) and an imatinib-responsive eosinophilic myeloproliferative disorder.
Cancer research 2004;64(20):7216-9.
2004: Bastie Jean-Noël; Garcia Isabel; Terré Christine; Cross Nicholas C P; Mahon Francois-Xavier; Castaigne Sylvie
Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor beta-gene.
Haematologica 2004;89(10):1263-4.
2004: Bunyan D J; Eccles D M; Sillibourne J; Wilkins E; Thomas N Simon; Shea-Simonds J; Duncan P J; Curtis C E; Robinson D O; Harvey J F; Cross N C P
Dosage analysis of cancer predisposition genes by multiplex ligation-dependent probe amplification.
British journal of cancer 2004;91(6):1155-9.
2004: Boultwood Jacqueline; Pellagatti Andrea; Watkins Fiona; Campbell Lisa J; Esoof Noor; Cross Nicholas C P; Eagleton Helen; Littlewood Tim J; Fidler Carrie; Wainscoat James S
Low expression of the putative tumour suppressor gene gravin in chronic myeloid leukaemia, myelodysplastic syndromes and acute myeloid leukaemia.
British journal of haematology 2004;126(4):508-11.
2004: Grand Effie K; Grand Francis H; Chase Andrew J; Ross Fiona M; Corcoran Martin M; Oscier David G; Cross Nicholas C P
Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome.
Genes, chromosomes & cancer 2004;40(1):78-83.
2004: Grand E K; Chase A J; Heath C; Rahemtulla A; Cross N C P
Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(5):962-6.
2004: Vizmanos José L; Novo Francisco J; Román José P; Baxter E Joanna; Lahortiga Idoya; Larráyoz María J; Odero María D; Giraldo Pilar; Calasanz María J; Cross Nicholas C P
NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder.
Cancer research 2004;64(8):2673-6.
2004: Roumiantsev Sergei; Krause Daniela S; Neumann Carola A; Dimitri Christopher A; Asiedu Frances; Cross Nicholas C P; Van Etten Richard A
Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations.
Cancer cell 2004;5(3):287-98.
2004: Heath Carol; Cross Nicholas C P
Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1.
The Journal of biological chemistry 2004;279(8):6666-73.
2004: Vizmanos José L; Hernández Roberto; Vidal María J; Larráyoz María J; Odero María D; Marín Julián; Ardanaz María T; Calasanz María J; Cross Nicholas C P
Clinical variability of patients with the t(6;8)(q27;p12) and FGFR1OP-FGFR1 fusion: two further cases.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(6):534-7.
2003: Zhang L Y; Ibbotson R E; Orchard J A; Gardiner A C; Seear R V; Chase A J; Oscier D G; Cross N C P
P2X7 polymorphism and chronic lymphocytic leukaemia: lack of correlation with incidence, survival and abnormalities of chromosome 12.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(11):2097-100.
2003: Pardanani Animesh; Ketterling Rhett P; Brockman Stephanie R; Flynn Heather C; Paternoster Sarah F; Shearer Brandon M; Reeder Terra L; Li Chin-Yang; Cross Nicholas C P; Cools Jan; Gilliland D Gary; Dewald Gordon W; Tefferi Ayalew
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.
Blood 2003;102(9):3093-6.
2003: Pardanani A; Elliott M; Reeder T; Li C Y; Baxter E J; Cross N C P; Tefferi A
Imatinib for systemic mast-cell disease.
Lancet 2003;362(9383):535-6.
2003: Pardanani Animesh; Reeder Terra; Porrata Luis F; Li Chin-Yang; Tazelaar Henry D; Baxter E Joanna; Witzig Thomas E; Cross Nicholas C P; Tefferi Ayalew
Imatinib therapy for hypereosinophilic syndrome and other eosinophilic disorders.
Blood 2003;101(9):3391-7.
2003: Deguchi Kenji; Ayton Paul M; Carapeti Melina; Kutok Jeffery L; Snyder Cynthia S; Williams Ifor R; Cross Nicholas C P; Glass Christopher K; Cleary Michael L; Gilliland D Gary
MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.
Cancer cell 2003;3(3):259-71.
2003: Cools Jan; DeAngelo Daniel J; Gotlib Jason; Stover Elizabeth H; Legare Robert D; Cortes Jorges; Kutok Jeffrey; Clark Jennifer; Galinsky Ilene; Griffin James D; Cross Nicholas C P; Tefferi Ayalew; Malone James; Alam Rafeul; Schrier Stanley L; Schmid Janet; Rose Michal; Vandenberghe Peter; Verhoef Gregor; Boogaerts Marc; Wlodarska Iwona; Kantarjian Hagop; Marynen Peter; Coutre Steven E; Stone Richard; Gilliland D Gary
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.
The New England journal of medicine 2003;348(13):1201-14.
2003: Reiter Andreas; Saussele Susanne; Grimwade David; Wiemels Joseph L; Segal Mark R; Lafage-Pochitaloff Marina; Walz Christoph; Weisser Andreas; Hochhaus Andreas; Willer Andreas; Reichert Anja; Büchner Thomas; Lengfelder Eva; Hehlmann Rüdiger; Cross Nicholas C P
Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia.
Genes, chromosomes & cancer 2003;36(2):175-88.
2003: Baxter E Joanna; Kulkarni Shashikant; Vizmanos José-Luis; Jaju Rina; Martinelli Giovanni; Testoni Nicoletta; Hughes George; Salamanchuk Zoryana; Calasanz Maria José; Lahortiga Idoya; Pocock Christopher F; Dang Raymond; Fidler Carrie; Wainscoat James S; Boultwood Jacqueline; Cross Nicholas C P
Novel translocations that disrupt the platelet-derived growth factor receptor beta (PDGFRB) gene in BCR-ABL-negative chronic myeloproliferative disorders.
British journal of haematology 2003;120(2):251-6.
2002: Hochhaus A; Kreil S; Corbin A S; La Rosée P; Müller M C; Lahaye T; Hanfstein B; Schoch C; Cross N C P; Berger U; Gschaidmeier H; Druker B J; Hehlmann R
Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(11):2190-6.
2002: Apperley Jane F; Gardembas Martine; Melo Junia V; Russell-Jones Robin; Bain Barbara J; Baxter E Joanna; Chase Andrew; Chessells Judith M; Colombat Marie; Dearden Claire E; Dimitrijevic Sasa; Mahon François-X; Marin David; Nikolova Zariana; Olavarria Eduardo; Silberman Sandra; Schultheis Beate; Cross Nicholas C P; Goldman John M
Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta.
The New England journal of medicine 2002;347(7):481-7.
2002: Cross N C P; Reiter A
Tyrosine kinase fusion genes in chronic myeloproliferative diseases.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(7):1207-12.
2002: Baxter E Joanna; Hochhaus Andreas; Bolufer Pascual; Reiter Andreas; Fernandez José M; Senent Leonor; Cervera José; Moscardo Federico; Sanz Miguel A; Cross Nicholas C P
The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA.
Human molecular genetics 2002;11(12):1391-7.
2002: Billio Atto; Steer E Joanna; Pianezze Graziano; Svaldi Mirjia; Casin Marco; Amato Barbara; Coser Paolo; Cross Nicholas C P
A further case of acute myeloid leukaemia with inv(8)(p11q13) and MOZ-TIF2 fusion.
Haematologica 2002;87(5):ECR15.
2002: Steer E Joanna; Cross Nicholas C P
Myeloproliferative disorders with translocations of chromosome 5q31-35: role of the platelet-derived growth factor receptor Beta.
Acta haematologica 2002;107(2):113-22.
2002: Granjo E; Lima M; Lopes J M; Dória S; Orfão A; Ying S; Barata L T; Miranda M; Cross N C P; Bain B J
Chronic eosinophilic leukaemia presenting with erythroderma, mild eosinophilia and hyper-IgE: clinical, immunological and cytogenetic features and therapeutic approach. A case report.
Acta haematologica 2002;107(2):108-12.
2002: Macdonald D; Reiter A; Cross N C P
The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1.
Acta haematologica 2002;107(2):101-7.
2001: Demiroglu A; Steer E J; Heath C; Taylor K; Bentley M; Allen S L; Koduru P; Brody J P; Hawson G; Rodwell R; Doody M L; Carnicero F; Reiter A; Goldman J M; Melo J V; Cross N C
The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins.
Blood 2001;98(13):3778-83.
2001: Mughal T I; Yong A; Szydlo R M; Dazzi F; Olavarria E; van Rhee F; Kaeda J; Cross N C; Craddock C; Kanfer E; Apperley J; Goldman J M
Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse.
British journal of haematology 2001;115(3):569-74.
2001: Sohal J; Chase A; Mould S; Corcoran M; Oscier D; Iqbal S; Parker S; Welborn J; Harris R I; Martinelli G; Montefusco V; Sinclair P; Wilkins B S; van den Berg H; Vanstraelen D; Goldman J M; Cross N C
Identification of four new translocations involving FGFR1 in myeloid disorders.
Genes, chromosomes & cancer 2001;32(2):155-63.
2001: Chase A; Huntly B J; Cross N C
Cytogenetics of chronic myeloid leukaemia.
Best practice & research. Clinical haematology 2001;14(3):553-71.
2001: Hochhaus A; Kreil S; Corbin A; La Rosée P; Lahaye T; Berger U; Cross N C; Linkesch W; Druker B J; Hehlmann R; Gambacorti- Passerini C; Corneo G; D'Incalci M
Roots of clinical resistance to STI-571 cancer therapy.
Science (New York, N.Y.) 2001;293(5538):2163.
2001: Jaju R J; Fidler C; Haas O A; Strickson A J; Watkins F; Clark K; Cross N C; Cheng J F; Aplan P D; Kearney L; Boultwood J; Wainscoat J S
A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.
Blood 2001;98(4):1264-7.
2001: Lewis J L; Chinswangwatanakul W; Zheng B; Marley S B; Nguyen D X; Cross N C; Banerji L; Glassford J; Thomas N S; Goldman J M; Lam E W; Gordon M Y
The influence of INK4 proteins on growth and self-renewal kinetics of hematopoietic progenitor cells.
Blood 2001;97(9):2604-10.
2001: Olavarria E; Kanfer E; Szydlo R; Kaeda J; Rezvani K; Cwynarski K; Pocock C; Dazzi F; Craddock C; Apperley J F; Cross N C; Goldman J M
Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia.
Blood 2001;97(6):1560-5.
2000: Dazzi F; Szydlo R M; Cross N C; Craddock C; Kaeda J; Kanfer E; Cwynarski K; Olavarria E; Yong A; Apperley J F; Goldman J M
Durability of responses following donor lymphocyte infusions for patients who relapse after allogeneic stem cell transplantation for chronic myeloid leukemia.
Blood 2000;96(8):2712-6.
2000: Kulkarni S; Heath C; Parker S; Chase A; Iqbal S; Pocock C F; Kaeda J; Cwynarski K; Goldman J M; Cross N C
Fusion of H4/D10S170 to the platelet-derived growth factor receptor beta in BCR-ABL-negative myeloproliferative disorders with a t(5;10)(q33;q21).
Cancer research 2000;60(13):3592-8.
2000: Hochhaus A; Weisser A; La Rosée P; Emig M; Müller M C; Saussele S; Reiter A; Kuhn C; Berger U; Hehlmann R; Cross N C
Detection and quantification of residual disease in chronic myelogenous leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(6):998-1005.
2000: Smith B M; Slade M J; English J; Graham H; Lüchtenborg M; Sinnett H D; Cross N C; Coombes R C
Response of circulating tumor cells to systemic therapy in patients with metastatic breast cancer: comparison of quantitative polymerase chain reaction and immunocytochemical techniques.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(7):1432-9.
2000: Chase A; Pickard J; Szydlo R; Coulthard S; Goldman J M; Cross N C
Non-random involvement of chromosome 13 in patients with persistent or relapsed disease after bone-marrow transplantation for chronic myeloid leukemia.
Genes, chromosomes & cancer 2000;27(3):278-84.
2000: Dazzi F; Szydlo R M; Craddock C; Cross N C; Kaeda J; Chase A; Olavarria E; van Rhee F; Kanfer E; Apperley J F; Goldman J M
Comparison of single-dose and escalating-dose regimens of donor lymphocyte infusion for relapse after allografting for chronic myeloid leukemia.
Blood 2000;95(1):67-71.
2000: Hochhaus A; Reiter A; Saussele S; Reichert A; Emig M; Kaeda J; Schultheis B; Berger U; Shepherd P C; Allan N C; Hehlmann R; Goldman J M; Cross N C
Molecular heterogeneity in complete cytogenetic responders after interferon-alpha therapy for chronic myelogenous leukemia: low levels of minimal residual disease are associated with continuing remission. German CML Study Group and the UK MRC CML Study Group.
Blood 2000;95(1):62-6.
2000: Sohal J; Reiter A; Goldman J M; Cross N C
Cloning of ZNF237, a novel member of the MYM gene family that maps to human chromosome 13q11-->q12.
Cytogenetics and cell genetics 2000;89(1-2):24-8.
1999: Emig M; Saussele S; Wittor H; Weisser A; Reiter A; Willer A; Berger U; Hehlmann R; Cross N C; Hochhaus A
Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(11):1825-32.
1999: Smedley D; Demiroglu A; Abdul-Rauf M; Heath C; Cooper C; Shipley J; Cross N C
ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5.
Neoplasia (New York, N.Y.) 1999;1(4):349-55.
1999: Grand F; Kulkarni S; Chase A; Goldman J M; Gordon M; Cross N C
Frequent deletion of hSNF5/INI1, a component of the SWI/SNF complex, in chronic myeloid leukemia.
Cancer research 1999;59(16):3870-4.
1999: Carapeti M; Aguiar R C; Watmore A E; Goldman J M; Cross N C
Consistent fusion of MOZ and TIF2 in AML with inv(8)(p11q13).
Cancer genetics and cytogenetics 1999;113(1):70-2.
1999: MacDonald D H; Lahiri D; Chase A; Sohal J; Goldman J M; Cross N C
A case of myelofibrosis with a t(4;13)(q25;q12): evidence for involvement of a second 13q12 locus in chronic myeloproliferative disorders.
British journal of haematology 1999;105(3):771-4.
1999: Macdonald D H; Lahiri D; Sampath A; Chase A; Sohal J; Cross N C
Cloning and characterization of RNF6, a novel RING finger gene mapping to 13q12.
Genomics 1999;58(1):94-7.
1999: Slade M J; Smith B M; Sinnett H D; Cross N C; Coombes R C
Quantitative polymerase chain reaction for the detection of micrometastases in patients with breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(3):870-9.
1999: Chase A; Reiter A; Burci L; Cazzaniga G; Biondi A; Pickard J; Roberts I A; Goldman J M; Cross N C
Fusion of ETV6 to the caudal-related homeobox gene CDX2 in acute myeloid leukemia with the t(12;13)(p13;q12).
Blood 1999;93(3):1025-31.
1999: Kulkarni S; Reiter A; Smedley D; Goldman J M; Cross N C
The genomic structure of ZNF198 and location of breakpoints in the t(8;13) myeloproliferative syndrome.
Genomics 1999;55(1):118-21.
1999: Sohal J; Chase A; Goldman J M; Cross N C
Assignment of ZNF262 to human chromosome band 1p34-->p32 by in situ hybridization.
Cytogenetics and cell genetics 1999;85(3-4):306-7.
1998: Cross N C
Minimal residual disease in chronic myeloid leukaemia.
Hematology and cell therapy 1998;40(5):224-8.
1998: Carapeti M; Aguiar R C; Chase A; Goldman J M; Cross N C
Assignment of the steroid receptor coactivator-1 (SRC-1) gene to human chromosome band 2p23.
Genomics 1998;52(2):242-4.
1998: Reiter A; Marley S B; Hochhaus A; Sohal J; Raanani P; Hehlmann R; Gordon M Y; Goldman J M; Cross N C
BCR-ABL-positive progenitors in chronic myeloid leukaemia patients in complete cytogenetic remission after treatment with interferon-alpha.
British journal of haematology 1998;102(5):1271-8.
1998: Carapeti M; Aguiar R C; Sill H; Goldman J M; Cross N C
Aberrant transcripts of the FHIT gene are expressed in normal and leukaemic haemopoietic cells.
British journal of cancer 1998;78(5):601-5.
1998: Reiter A; Sohal J; Kulkarni S; Chase A; Macdonald D H; Aguiar R C; Gonçalves C; Hernandez J M; Jennings B A; Goldman J M; Cross N C
Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome.
Blood 1998;92(5):1735-42.
1998: van Rhee F; Savage D; Blackwell J; Orchard K; Dazzi F; Lin F; Chase A; Bungey J; Cross N C; Apperley J; Szydlo R; Goldman J M
Adoptive immunotherapy for relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: equal efficacy of lymphocytes from sibling and matched unrelated donors.
Bone marrow transplantation 1998;21(10):1055-61.
1998: Carapeti M; Aguiar R C; Goldman J M; Cross N C
A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia.
Blood 1998;91(9):3127-33.
1997: Raanani P; Dazzi F; Sohal J; Szydlo R M; van Rhee F; Reiter A; Lin F; Goldman J M; Cross N C
The rate and kinetics of molecular response to donor leucocyte transfusions in chronic myeloid leukaemia patients treated for relapse after allogeneic bone marrow transplantation.
British journal of haematology 1997;99(4):945-50.
1997: Aguiar R C; Chase A; Oscier D G; Carapeti M; Goldman J M; Cross N C
Characterization of a t(10;12)(q24;p13) in a case of CML in transformation.
Genes, chromosomes & cancer 1997;20(4):408-11.
1997: Aguiar R C; Chase A; Coulthard S; Macdonald D H; Carapeti M; Reiter A; Sohal J; Lennard A; Goldman J M; Cross N C
Abnormalities of chromosome band 8p11 in leukemia: two clinical syndromes can be distinguished on the basis of MOZ involvement.
Blood 1997;90(8):3130-5.
1997: Carapeti M; Soede-Bobok A; Hochhaus A; Sill H; Touw I P; Goldman J M; Cross N C
Rarity of dominant-negative mutations of the G-CSF receptor in patients with blast crisis of chronic myeloid leukemia or de novo acute leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(7):1005-8.
1997: Cross N C
Assessing residual leukaemia.
Baillière's clinical haematology 1997;10(2):389-403.
1997: Carapeti M; Goldman J M; Cross N C
Dominant-negative mutations of the Wilms' tumour predisposing gene (WT1) are infrequent in CML blast crisis and de novo acute leukaemia.
European journal of haematology 1997;58(5):346-9.
1997: Aguiar R C; Sill H; Goldman J M; Cross N C
The commonly deleted region at 9p21-22 in lymphoblastic leukemias spans at least 400 kb and includes p16 but not p15 or the IFN gene cluster.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(2):233-8.
1996: Aguiar R C; Sohal J; van Rhee F; Carapeti M; Franklin I M; Goldstone A H; Goldman J M; Cross N C
TEL-AML1 fusion in acute lymphoblastic leukaemia of adults. M.R.C. Adult Leukaemia Working Party.
British journal of haematology 1996;95(4):673-7.
1996: Lin F; Kirkland M A; van Rhee F V; Chase A; Coulthard S; Bungey J; Goldman J M; Cross N C
Molecular analysis of transient cytogenetic relapse after allogeneic bone marrow transplantation for chronic myeloid leukaemia.
Bone marrow transplantation 1996;18(6):1147-52.
1996: Seale J R; Varma S; Swirsky D M; Pandolfi P P; Goldman J M; Cross N C
Quantification of PML-RAR alpha transcripts in acute promyelocytic leukaemia: explanation for the lack of sensitivity of RT-PCR for the detection of minimal residual disease and induction of the leukaemia-specific mRNA by alpha interferon.
British journal of haematology 1996;95(1):95-101.
1996: Aguiar R C; Sill H; Hochhaus A; Goldman J M; Cross N C
Molecular investigation of secondary chronic myeloid leukemia.
Blood 1996;88(7):2808-9.
1996: Hochhaus A; Reiter A; Skladny H; Melo J V; Sick C; Berger U; Guo J Q; Arlinghaus R B; Hehlmann R; Goldman J M; Cross N C
A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome-negative chronic myelogenous leukemia.
Blood 1996;88(6):2236-40.
1996: Carapeti M; Goldman J M; Cross N C
Overexpression of EVI-1 in blast crisis of chronic myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(9):1561.
1996: Aguiar R C; Dahia P L; Sill H; Toledo S P; Goldman J M; Cross N C
Deletion analysis of the p16 tumour suppressor gene in phaeochromocytomas.
Clinical endocrinology 1996;45(1):93-6.
1996: Sill H; Goldman J M; Cross N C
Rarity of microsatellite alterations in acute myeloid leukaemia.
British journal of cancer 1996;74(2):255-7.
1996: Melo J V; Yan X H; Diamond J; Lin F; Cross N C; Goldman J M
Reverse transcription/polymerase chain reaction (RT/PCR) amplification of very small numbers of transcripts: the risk in misinterpreting negative results.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(7):1217-21.
1996: van Rhee F; Hochhaus A; Lin F; Melo J V; Goldman J M; Cross N C
p190 BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemias.
Blood 1996;87(12):5213-7.
1996: Hochhaus A; Lin F; Reiter A; Skladny H; Hehlmann R; Goldman J M; Cross N C
Quantitative molecular methods to monitor the response of CML patients to interferon-alpha.
Bone marrow transplantation 1996;17 Suppl 3():S41-4.
1996: Lin F; van Rhee F; Goldman J M; Cross N C
Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation.
Blood 1996;87(10):4473-8.
1996: Sill H; Rule S A; Joske D J; Chase A; Lin F; Goldman J M; Cross N C
Reconstitution with Philadelphia chromosome-negative recipient haematopoiesis early after allogeneic BMT for CML.
Bone marrow transplantation 1996;17(3):453-5.
1996: Zhang J G; Lin F; Chase A; Goldman J M; Cross N C
Comparison of genomic DNA and cDNA for detection of residual disease after treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation.
Blood 1996;87(6):2588-93.
1996: Sill H; Aguiar R C; Schmidt H; Hochhaus A; Goldman J M; Cross N C
Mutational analysis of the p15 and p16 genes in acute leukaemias.
British journal of haematology 1996;92(3):681-3.
1996: Hochhaus A; Lin F; Reiter A; Skladny H; Mason P J; van Rhee F; Shepherd P C; Allan N C; Hehlmann R; Goldman J M; Cross N C
Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction.
Blood 1996;87(4):1549-55.
1995: Macdonald D; Aguiar R C; Mason P J; Goldman J M; Cross N C
A new myeloproliferative disorder associated with chromosomal translocations involving 8p11: a review.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(10):1628-30.
1995: Hochhaus A; Lin F; Reiter A; Skladny H; van Rhee F; Shepherd P C; Allan N C; Hehlmann R; Goldman J M; Cross N C
Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-alpha.
British journal of haematology 1995;91(1):126-31.
1995: Aguiar R C; Macdonald D; Mason P J; Cross N C; Goldman J M
Myeloproliferative disorder associated with 8p11 translocations.
Blood 1995;86(2):834-5.
1995: Lin F; Chase A; Bungey J; Goldman J M; Cross N C
Correlation between the proportion of Philadelphia chromosome-positive metaphase cells and levels of BCR-ABL mRNA in chronic myeloid leukaemia.
Genes, chromosomes & cancer 1995;13(2):110-4.
1995: van Rhee F; Kasprzyk A; Jamil A; Dickinson H; Lin F; Cross N C; Galvin M C; Goldman J M; Secker-Walker L M
Detection of the BCR-ABL gene by reverse transcription/polymerase chain reaction and fluorescence in situ hybridization in a patient with Philadelphia chromosome negative acute lymphoblastic leukaemia.
British journal of haematology 1995;90(1):225-8.
1995: Zhang J G; Goldman J M; Cross N C
Characterization of genomic BCR-ABL breakpoints in chronic myeloid leukaemia by PCR.
British journal of haematology 1995;90(1):138-46.
1995: Cross N C
Quantitative PCR techniques and applications.
British journal of haematology 1995;89(4):693-7.
1995: Sill H; Goldman J M; Cross N C
Homozygous deletions of the p16 tumor-suppressor gene are associated with lymphoid transformation of chronic myeloid leukemia.
Blood 1995;85(8):2013-6.
1995: van Rhee F; Marks D I; Lin F; Szydlo R M; Hochhaus A; Treleaven J; Delord C; Cross N C; Goldman J M
Quantification of residual disease in Philadelphia-positive acute lymphoblastic leukemia: comparison of blood and bone marrow.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(2):329-35.
1994: Silly H; Chase A; Mills K I; Apfelbeck U; Sormann S; Goldman J M; Cross N C
No evidence for microsatellite instability or consistent loss of heterozygosity at selected loci in chronic myeloid leukaemia blast crisis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(11):1923-8.
1994: van Rhee F; Lin F; Cross N C; Reid C D; Lakhani A K; Szydlo R M; Goldman J M
Detection of residual leukaemia more than 10 years after allogeneic bone marrow transplantation for chronic myelogenous leukaemia.
Bone marrow transplantation 1994;14(4):609-12.
1994: Garicochea B; van Rhee F; Spencer A; Chase A; Lin F; Cross N C; Goldman J M
Aplasia after donor lymphocyte infusion (DLI) for CML in relapse after sex-mismatched BMT: recovery of donor-type haemopoiesis predicted by non-isotopic in situ hybridization (ISH).
British journal of haematology 1994;88(2):400-2.
1994: van Rhee F; Lin F; Cullis J O; Spencer A; Cross N C; Chase A; Garicochea B; Bungey J; Barrett J; Goldman J M
Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse.
Blood 1994;83(11):3377-83.
1994: Macdonald D; Sheerin S M; Cross N C; Spencer A; Goldman J M
An atypical myeloproliferative disorder with t(8;13) (p11;q12): a third case.
British journal of haematology 1994;86(4):879-80.
1994: Lin F; Goldman J M; Cross N C
A comparison of the sensitivity of blood and bone marrow for the detection of minimal residual disease in chronic myeloid leukaemia.
British journal of haematology 1994;86(3):683-5.
1994: Cross N C; Melo J V; Feng L; Goldman J M
An optimized multiplex polymerase chain reaction (PCR) for detection of BCR-ABL fusion mRNAs in haematological disorders.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(1):186-9.
1994: Bi S; Barton C M; Lemoine N R; Cross N C; Goldman J M
Retroviral transduction of Philadelphia-positive chronic myeloid leukemia cells with a human mutant p53 cDNA and its effect on in vitro proliferation.
Experimental hematology 1994;22(1):95-9.
1993: Cross N C; Feng L; Chase A; Bungey J; Hughes T P; Goldman J M
Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts in chronic myeloid leukemia patients after bone marrow transplantation.
Blood 1993;82(6):1929-36.
1993: Kirkland M A; O'Brien S G; McDonald C; Davidson R J; Cross N C; Goldman J M
BCR-ABL antisense purging in chronic myeloid leukaemia.
Lancet 1993;342(8871):614.
1993: Cross N C; Hughes T P; Feng L; O'Shea P; Bungey J; Marks D I; Ferrant A; Martiat P; Goldman J M
Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: correlations with acute graft-versus-host disease and relapse.
British journal of haematology 1993;84(1):67-74.
1993: Melo J V; Gordon D E; Cross N C; Goldman J M
The ABL-BCR fusion gene is expressed in chronic myeloid leukemia.
Blood 1993;81(1):158-65.
1993: Cullis J O; Szydlo R M; Cross N C; Marks D I; Schwarer A P; Hughes T P; Mackinnon S; Hale G; Waldmann H; Hows J M
Matched unrelated donor bone marrow transplantation for chronic myeloid leukaemia in chronic phase: comparison of ex vivo and in vivo T-cell depletion.
Bone marrow transplantation 1993;11 Suppl 1():107-11.
1993: Cross N C; Feng L; Bungey J; Goldman J M
Minimal residual disease after bone marrow transplant for chronic myeloid leukaemia detected by the polymerase chain reaction.
Leukemia & lymphoma 1993;11 Suppl 1():39-43.
1990: Cross N C; Cox T M
Partial aldolase B gene deletions in hereditary fructose intolerance.
American journal of human genetics 1990;47(1):101-6.
1990: Cross N C; Stojanov L M; Cox T M
A new aldolase B variant, N334K, is a common cause of hereditary fructose intolerance in Yugoslavia.
Nucleic acids research 1990;18(7):1925.
1990: Cross N C; de Franchis R; Sebastio G; Dazzo C; Tolan D R; Gregori C; Odievre M; Vidailhet M; Romano V; Mascali G
Molecular analysis of aldolase B genes in hereditary fructose intolerance.
Lancet 1990;335(8685):306-9.
1990: Cross N C; Cox T M
Hereditary fructose intolerance.
The International journal of biochemistry 1990;22(7):685-9.
1989: Cross N C; Cox T M
Molecular analysis of aldolase B genes in the diagnosis of hereditary fructose intolerance in the United Kingdom.
The Quarterly journal of medicine 1989;73(271):1015-20.
1988: de Franchis R; Cross N C; Foulkes N S; Cox T M
A potent inhibitor of Taq polymerase copurifies with human genomic DNA.
Nucleic acids research 1988;16(21):10355.
1988: Foulkes N S; Pandolfi de Rinaldis P P; Macdonnell J; Cross N C; Luzzatto L
Polymerase chain reaction automated at low cost.
Nucleic acids research 1988;16(12):5687-8.

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