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Lourdes Cruz

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Lemmuel L Tayo; Bingwen Lu; Lourdes J Cruz; John R Yates
Proteomic analysis provides insights on venom processing in Conus textile.
Rhodora V Azanza; Lourdes J Cruz; Flerida A Cariño; Alelea G Blanco; Vito M. Butardo
Paralytic shellfish toxin concentration and cell density changes in Pyrodinium bahamense -Noctiluca scintillans feeding experiments.
Gloria P Corpuz; Richard B Jacobsen; Elsie C Jimenez; Maren Watkins; Craig Walker; Clark Colledge; James E Garrett; Owen McDougal; Wenqin Li; William R Gray; David R Hillyard; Jean Rivier; J Michael McIntosh; Lourdes J Cruz; Baldomero M Olivera
Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms.

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All Publications

2010: Lemmuel L Tayo; Bingwen Lu; Lourdes J Cruz; John R Yates
Proteomic analysis provides insights on venom processing in Conus textile.
Journal of proteome research 2010;9(5):2292-301.
2010: Rhodora V Azanza; Lourdes J Cruz; Flerida A Cariño; Alelea G Blanco; Vito M. Butardo
Paralytic shellfish toxin concentration and cell density changes in Pyrodinium bahamense -Noctiluca scintillans feeding experiments.
Toxicon : official journal of the International Society on Toxinology 2010;55(5):1017-23.
2005: Gloria P Corpuz; Richard B Jacobsen; Elsie C Jimenez; Maren Watkins; Craig Walker; Clark Colledge; James E Garrett; Owen McDougal; Wenqin Li; William R Gray; David R Hillyard; Jean Rivier; J Michael McIntosh; Lourdes J Cruz; Baldomero M Olivera
Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms.
Biochemistry 2005;44(22):8176-86.
2004: Rohan A Davis; Gina C Mangalindan; Zenaida P Bojo; Rowena R Antemano; Nell O Rodriguez; Gisela P Concepcion; Shiela C Samson; Dennis de Guzman; Lourdes J Cruz; Deniz Tasdemir; Mary Kay Harper; Xidong Feng; Guy T Carter; Chris M Ireland
Microcionamides A and B, bioactive peptides from the philippine sponge Clathria (Thalysias) abietina.
The Journal of organic chemistry 2004;69(12):4170-6.
2004: Ameurfina D Santos; J Michael McIntosh; David R Hillyard; Lourdes J Cruz; Baldomero M Olivera
The A-superfamily of conotoxins: structural and functional divergence.
The Journal of biological chemistry 2004;279(17):17596-606.
2003: Julita S Imperial; Maren Watkins; Ping Chen; David R Hillyard; Lourdes J Cruz; Baldomero M Olivera
The augertoxins: biochemical characterization of venom components from the toxoglossate gastropod Terebra subulata.
Toxicon : official journal of the International Society on Toxinology 2003;42(4):391-8.
2003: Elsie C Jimenez; Reshma P Shetty; Marcelina Lirazan; Jean Rivier; Craig Walker; Fe C Abogadie; Doju Yoshikami; Lourdes J Cruz; Baldomero M Olivera
Novel excitatory Conus peptides define a new conotoxin superfamily.
Journal of neurochemistry 2003;85(3):610-21.
2002: Elsie C Jimenez; Sean D Donevan; Craig Walker; Li-Ming Zhou; Jake Nielsen; Lourdes J Cruz; Heather Armstrong; H White; Baldomero M Olivera
Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency.
Epilepsy research 2002;51(1-2):73-80.
2002: Marcelina Lirazan; Elsie C Jimenez; A Grey Craig; Baldomero M Olivera; Lourdes J Cruz
Conophysin-R, a Conus radiatus venom peptide belonging to the neurophysin family.
Toxicon : official journal of the International Society on Toxinology 2002;40(7):901-8.
2001: D J Espiritu; Maren Watkins; V Dia-Monje; George Cartier; Lourdes J Cruz; Baldomero M Olivera
Venomous cone snails: molecular phylogeny and the generation of toxin diversity.
Toxicon : official journal of the International Society on Toxinology 2001;39(12):1899-916.
2001: Elsie C Jimenez; Maren Watkins; L J Juszczak; Lourdes J Cruz; Baldomero M Olivera
Contryphans from Conus textile venom ducts.
Toxicon : official journal of the International Society on Toxinology 2001;39(6):803-8.
2001: Baldomero M Olivera; Lourdes J Cruz
Conotoxins, in retrospect.
Toxicon : official journal of the International Society on Toxinology 2001;39(1):7-14.
2000: J Michael McIntosh; G O Corpuz; Richard T Layer; James E Garrett; John D Wagstaff; Grzegorz Bulaj; A Vyazovkina; Doju Yoshikami; Lourdes J Cruz; Baldomero M Olivera
Isolation and characterization of a novel conus peptide with apparent antinociceptive activity.
The Journal of biological chemistry 2000;275(42):32391-7.
2000: Gina C Mangalindan; M T Talaue; Lourdes J Cruz; Scott Franzblau; Linda B Adams; Adam Richardson; Chris M Ireland; Gisela P Concepcion
Agelasine F from a Philippine Agelas sp. sponge exhibits in vitro antituberculosis activity.
Planta medica 2000;66(4):364-5.
2000: Marcelina Lirazan; D Hooper; G P Corpuz; C A Ramilo; Pradip K Bandyopadhyay; Lourdes J Cruz; Baldomero M Olivera
The spasmodic peptide defines a new conotoxin superfamily.
Biochemistry 2000;39(7):1583-8.
2000: H White; RT McCabe; H Armstrong; Sean D Donevan; Lourdes J Cruz; Fe C Abogadie; Josep Torres; Jean E Rivier; I Paarmann; Michael Hollmann; Baldomero M Olivera
In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus.
The Journal of pharmacology and experimental therapeutics 2000;292(1):425-32.
1999: Baldomero M Olivera; Lourdes J Cruz; Doju Yoshikami
Effects of Conus peptides on the behavior of mice.
Current opinion in neurobiology 1999;9(6):772-7.
1999: Craig S Walker; D Steel; Richard B Jacobsen; Marcelina Lirazan; Lourdes J Cruz; D Hooper; Reshma P Shetty; R C DelaCruz; Jacob S Nielsen; Li-Ming Zhou; Pradip K Bandyopadhyay; A Grey Craig; Baldomero M Olivera
The T-superfamily of conotoxins.
The Journal of biological chemistry 1999;274(43):30664-71.
1999: Richard B Jacobsen; Elsie C Jimenez; R G De la Cruz; William R Gray; Lourdes J Cruz; Baldomero M Olivera
A novel D-leucine-containing Conus peptide: diverse conformational dynamics in the contryphan family.
The journal of peptide research : official journal of the American Peptide Society 1999;54(2):93-9.
1999: A Grey Craig; T Norberg; D Griffin; Carl A Hoeger; M Akhtar; K Schmidt; William Low; John Dykert; E Richelson; V Navarro; Jean Mazella; Maren Watkins; David R Hillyard; Julita S Imperial; Lourdes J Cruz; Baldomero M Olivera
Contulakin-G, an O-glycosylated invertebrate neurotensin.
The Journal of biological chemistry 1999;274(20):13752-9.
1999: J Michael McIntosh; Baldomero M Olivera; Lourdes J Cruz
Conus peptides as probes for ion channels.
Methods in enzymology 1999;294():605-24.
1998: A Grey Craig; G Zafaralla; Lourdes J Cruz; Ameurfina D Santos; David R Hillyard; John Dykert; Jean E Rivier; William R Gray; Julita S Imperial; Richard DeLaCruz; Annett Sporning; Heinrich Terlau; Peter J. West; Doju Yoshikami; Baldomero M Olivera
An O-glycosylated neuroexcitatory conus peptide.
Biochemistry 1998;37(46):16019-25.
1998: KJ Shon; Baldomero M Olivera; Maren Watkins; Richard B Jacobsen; William R Gray; C Z Floresca; Lourdes J Cruz; David R Hillyard; A Brink; Heinrich Terlau; Doju Yoshikami
mu-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(12):4473-81.
1998: Richard B Jacobsen; Elsie C Jimenez; M Grilley; Maren Watkins; David R Hillyard; Lourdes J Cruz; Baldomero M Olivera
The contryphans, a D-tryptophan-containing family of Conus peptides: interconversion between conformers.
The journal of peptide research : official journal of the American Peptide Society 1998;51(3):173-9.
1997: A Grey Craig; Elsie C Jimenez; John Dykert; D B Nielsen; Jozsef Gulyas; Fe C Abogadie; J Porter; Jean E Rivier; Lourdes J Cruz; Baldomero M Olivera; J Michael McIntosh
A novel post-translational modification involving bromination of tryptophan. Identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom.
The Journal of biological chemistry 1997;272(8):4689-98.
1997: Elsie C Jimenez; A Grey Craig; Maren Watkins; David R Hillyard; William R Gray; Jozsef Gulyas; Jean E Rivier; Lourdes J Cruz; Baldomero M Olivera
Bromocontryphan: post-translational bromination of tryptophan.
Biochemistry 1997;36(5):989-94.
1996: E C Jimenéz; Baldomero M Olivera; William R Gray; Lourdes J Cruz
Contryphan is a D-tryptophan-containing Conus peptide.
The Journal of biological chemistry 1996;271(45):28002-5.
1996: Lourdes J Cruz
Primary structural motifs of Conus peptides.
Advances in experimental medicine and biology 1996;391():155-67.
1995: C Hopkins; M Grilley; C Miller; KJ Shon; Lourdes J Cruz; William R Gray; John Dykert; Jean Rivier; Doju Yoshikami; Baldomero M Olivera
A new family of Conus peptides targeted to the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1995;270(38):22361-7.
1994: KJ Shon; A Hasson; Micha E Spira; Lourdes J Cruz; William R Gray; Baldomero M Olivera
Delta-conotoxin GmVIA, a novel peptide from the venom of Conus gloriamaris.
Biochemistry 1994;33(38):11420-5.
1992: David R Hillyard; V D Monje; I M Mintz; Bruce P Bean; L Nadasdi; J Ramachandran; GP Miljanich; A Azimi-Zoonooz; J Michael McIntosh; Lourdes J Cruz
A new Conus peptide ligand for mammalian presynaptic Ca2+ channels.
Neuron 1992;9(1):69-77.
1991: Baldomero M Olivera; Jean Rivier; jamie scott; David R Hillyard; Lourdes J Cruz
Conotoxins.
The Journal of biological chemistry 1991;266(33):22067-70.
1991: R A Myers; G C Zafaralla; William R Gray; J Abbott; Lourdes J Cruz; Baldomero M Olivera
alpha-Conotoxins, small peptide probes of nicotinic acetylcholine receptors.
Biochemistry 1991;30(38):9370-7.
1991: Baldomero M Olivera; Julita S Imperial; Lourdes J Cruz; V P Bindokas; V J Venema; Michael E Adams
Calcium channel-targeted polypeptide toxins.
Annals of the New York Academy of Sciences 1991;635():114-22.
1990: E E Mena; M F Gullak; M J Pagnozzi; K E Richter; Jean Rivier; Lourdes J Cruz; Baldomero M Olivera
Conantokin-G: a novel peptide antagonist to the N-methyl-D-aspartic acid (NMDA) receptor.
Neuroscience letters 1990;118(2):241-4.
1990: Baldomero M Olivera; Jean Rivier; C Clark; C A Ramilo; G P Corpuz; F C Abogadie; E E Mena; S R Woodward; David R Hillyard; Lourdes J Cruz
Diversity of Conus neuropeptides.
Science (New York, N.Y.) 1990;249(4966):257-63.
1990: J A Haack; Jean Rivier; Thomas N Parks; E E Mena; Lourdes J Cruz; Baldomero M Olivera
Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity.
The Journal of biological chemistry 1990;265(11):6025-9.
1990: S R Woodward; Lourdes J Cruz; Baldomero M Olivera; David R Hillyard
Constant and hypervariable regions in conotoxin propeptides.
The EMBO journal 1990;9(4):1015-20.
1989: Lourdes J Cruz; G Kupryszewski; G W LeCheminant; William R Gray; Baldomero M Olivera; Jean Rivier
mu-conotoxin GIIIA, a peptide ligand for muscle sodium channels: chemical synthesis, radiolabeling, and receptor characterization.
Biochemistry 1989;28(8):3437-42.
1989: David R Hillyard; Baldomero M Olivera; S Woodward; G P Corpuz; William R Gray; C A Ramilo; Lourdes J Cruz
A molluscivorous Conus toxin: conserved frameworks in conotoxins.
Biochemistry 1989;28(1):358-61.
1988: G C Zafaralla; C Ramilo; William R Gray; R Karlstrom; Baldomero M Olivera; Lourdes J Cruz
Phylogenetic specificity of cholinergic ligands: alpha-conotoxin SI.
Biochemistry 1988;27(18):7102-5.
1988: William R Gray; Baldomero M Olivera; Lourdes J Cruz
Peptide toxins from venomous Conus snails.
Annual review of biochemistry 1988;57():665-700.
1987: Jean Rivier; R Galyean; L Simon; Lourdes J Cruz; Baldomero M Olivera; William R Gray
Total synthesis and further characterization of the gamma-carboxyglutamate-containing "sleeper" peptide from Conus geographus venom.
Biochemistry 1987;26(26):8508-12.
1987: Lourdes J Cruz; V de Santos; G C Zafaralla; C A Ramilo; R Zeikus; William R Gray; Baldomero M Olivera
Invertebrate vasopressin/oxytocin homologs. Characterization of peptides from Conus geographus and Conus straitus venoms.
The Journal of biological chemistry 1987;262(33):15821-4.
1987: R E Yeager; Doju Yoshikami; J Rivier; Lourdes J Cruz; GP Miljanich
Transmitter release from presynaptic terminals of electric organ: inhibition by the calcium channel antagonist omega Conus toxin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(8):2390-6.
1987: E W McCleskey; Aaron P Fox; Daniel Feldman; Lourdes J Cruz; Baldomero M Olivera; Richard W Tsien; Doju Yoshikami
Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(12):4327-31.
1987: Baldomero M Olivera; Lourdes J Cruz; V de Santos; G W LeCheminant; D Griffin; R Zeikus; J Michael McIntosh; R Galyean; J Varga; William R Gray
Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using omega-conotoxin from Conus magus venom.
Biochemistry 1987;26(8):2086-90.
1987: Jean Rivier; R Galyean; William R Gray; A Azimi-Zonooz; J Michael McIntosh; Lourdes J Cruz; Baldomero M Olivera
Neuronal calcium channel inhibitors. Synthesis of omega-conotoxin GVIA and effects on 45Ca uptake by synaptosomes.
The Journal of biological chemistry 1987;262(3):1194-8.
1985: Baldomero M Olivera; William R Gray; R Zeikus; J Michael McIntosh; J Varga; J Rivier; V de Santos; Lourdes J Cruz
Peptide neurotoxins from fish-hunting cone snails.
Science (New York, N.Y.) 1985;230(4732):1338-43.
1985: Lourdes J Cruz; William R Gray; Baldomero M Olivera; R D Zeikus; L Kerr; Doju Yoshikami; E Moczydlowski
Conus geographus toxins that discriminate between neuronal and muscle sodium channels.
The Journal of biological chemistry 1985;260(16):9280-8.
1985: B M Olivera; J Michael McIntosh; C Clark; D Middlemas; William R Gray; Lourdes J Cruz
A sleep-inducing peptide from Conus geographus venom.
Toxicon : official journal of the International Society on Toxinology 1985;23(2):277-82.
1984: J Michael McIntosh; B M Olivera; Lourdes J Cruz; William R Gray
Gamma-carboxyglutamate in a neuroactive toxin.
The Journal of biological chemistry 1984;259(23):14343-6.
1984: B M Olivera; J Michael McIntosh; Lourdes J Cruz; F A Luque; William R Gray
Purification and sequence of a presynaptic peptide toxin from Conus geographus venom.
Biochemistry 1984;23(22):5087-90.
1983: William R Gray; J E Rivier; R Galyean; Lourdes J Cruz; Baldomero M Olivera
Conotoxin MI. Disulfide bonding and conformational states.
The Journal of biological chemistry 1983;258(20):12247-51.
1982: M McIntosh; Lourdes J Cruz; M W Hunkapiller; William R Gray; B M Olivera
Isolation and structure of a peptide toxin from the marine snail Conus magus.
Archives of biochemistry and biophysics 1982;218(1):329-34.
1981: David R Hillyard; M Rechsteiner; P Manlapaz-Ramos; Julita S Imperial; Lourdes J Cruz; Baldomero M Olivera
The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2.
The Journal of biological chemistry 1981;256(16):8491-7.
1981: William R Gray; A Luque; B M Olivera; J Barrett; Lourdes J Cruz
Peptide toxins from Conus geographus venom.
The Journal of biological chemistry 1981;256(10):4734-40.