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Elena Csernok

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Disorders

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Enzyme-Linked Immunosorbent Assay

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Fluorescent Antibody Technique, Indirect

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Lorenz Thurner; Marina Zaks; Klaus-Dieter Preuss; Evi Regitz; Rainer Maria Bohle; Elena Csernok; Natalie Fadle; Wolfgang L Gross; Andrea Hasenfus; Maria Kemele; Philipp Klemm; Thierry Martin; Jean-Louis Pasquali; Michael Pfreundschuh
Progranulin antibodies in autoimmune diseases.
Jan P Bremer; Elena Csernok; Wolfgang L Gross; Julia Holle; Frank Moosig
Getting rid of MPO-ANCA: a matter of disease subtype.
Nina Kesel; Dorothee Köhler; Peter Lamprecht; Martin Laudien; Michel Neidhart; Udo Schumacher; Elena Csernok; Renate E Gay; Steffen Gay; Wolfgang L Gross; Lena Herich; Konstanze Holl-Ulrich; Astrid Jüngel; Sebastian Ullrich
Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice.

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2013: Lorenz Thurner; Marina Zaks; Klaus-Dieter Preuss; Evi Regitz; Rainer Maria Bohle; Elena Csernok; Natalie Fadle; Wolfgang L Gross; Andrea Hasenfus; Maria Kemele; Philipp Klemm; Thierry Martin; Jean-Louis Pasquali; Michael Pfreundschuh
Progranulin antibodies in autoimmune diseases.
Journal of autoimmunity 2013;42():29-38.
2013: Jan P Bremer; Elena Csernok; Wolfgang L Gross; Julia Holle; Frank Moosig
Getting rid of MPO-ANCA: a matter of disease subtype.
Rheumatology (Oxford, England) 2013;52(4):752-4.
2012: Nina Kesel; Dorothee Köhler; Peter Lamprecht; Martin Laudien; Michel Neidhart; Udo Schumacher; Elena Csernok; Renate E Gay; Steffen Gay; Wolfgang L Gross; Lena Herich; Konstanze Holl-Ulrich; Astrid Jüngel; Sebastian Ullrich
Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice.
The American journal of pathology 2012;180(5):2144-55.
2012: Nishant Dwivedi; Bernhard Hellmich; Salar Khan; Kyriakos A Kirou; Bryan Knuckley; Ted R Mikuls; Linda Myers; Indira Neeli; Debendra Pattanaik; Mary K Crow; Elena Csernok; Paul R Thompson; Jagriti Upadhyay; Marko Z Radic
Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps.
Arthritis and rheumatism 2012;64(4):982-92.
2012: Julia U Holle; Wolfgang L Gross; Kristine Herrmann; Elena Csernok
Comparative analysis of different commercial ELISA systems for the detection of anti-neutrophil cytoplasm antibodies in ANCA-associated vasculitides.
Clinical and experimental rheumatology 2012;30(1 Suppl 70):S66-9.
2011: U Fagin; Juliane Fazio; Wolfgang L Gross; Kristina Krause; Frank Moosig; Antje Müller; Silke Pitann; Edith Wipfler-Freissmuth; Philip Bremer; Elena Csernok; Peter Lamprecht
Distinct proteinase 3-induced cytokine patterns in Wegener´s granulomatosis, Churg-Strauss syndrome, and healthy controls.
Clinical and experimental rheumatology 2011;29(1 Suppl 64):S57-62.
2010: Anna-Isabelle Kälsch; Elena Csernok; Dominik Münch; Rainer Birck; Benito A Yard; Wolfgang Gross; Thorsten Kälsch; Wilhelm H Schmitt
Use of highly sensitive C-reactive protein for followup of Wegener's granulomatosis.
The Journal of rheumatology 2010;37(11):2319-25.
2010: Julia U Holle; Wolfgang L Gross; Konstanze Holl-Ulrich; Petra Ambrosch; Bernhard Noelle; Marcus Both; Elena Csernok; Frank Moosig; Susanne Schinke; Eva Reinhold-Keller
Prospective long-term follow-up of patients with localised Wegener's granulomatosis: does it occur as persistent disease stage?
Annals of the rheumatic diseases 2010;69(11):1934-9.
2010: D Wibisono; Elena Csernok; Peter Lamprecht; J U Holle; Wolfgang L Gross; Frank Moosig
Serum HMGB1 levels are increased in active Wegener's granulomatosis and differentiate between active forms of ANCA-associated vasculitis.
Annals of the rheumatic diseases 2010;69(10):1888-9.
2010: Jan Loock; Peter Lamprecht; Christian Timmann; Ulrich Mrowietz; Elena Csernok; Wolfgang L Gross
Genetic predisposition (NLRP3 V198M mutation) for IL-1-mediated inflammation in a patient with Schnitzler syndrome.
The Journal of allergy and clinical immunology 2010;125(2):500-2.
2010: Sebastian Klapa; Antje Mueller; Elena Csernok; U Fagin; Paul Klenerman; Konstanze Holl-Ulrich; Wolfgang L Gross; Peter Lamprecht
Lower numbers of FoxP3 and CCR4 co-expressing cells in an elevated subpopulation of CD4+CD25high regulatory T cells from Wegener's granulomatosis.
Clinical and experimental rheumatology 2010;28(1 Suppl 57):72-80.
2010: Bo Jiang; Evelin Grage-Griebenow; Elena Csernok; Kristine Butherus; Stefan Ehlers; Wolfgang L Gross; Julia U Holle
The role of proteinase 3 (PR3) and the protease-activated receptor-2 (PAR-2) pathway in dendritic cell (DC) maturation of human-DC-like monocytes and murine DC.
Clinical and experimental rheumatology 2010;28(1 Suppl 57):56-61.
2010: Martin Laudien; Stefan D Gadola; Rainer Podschun; Jürgen Hedderich; Jens Paulsen; Eva Reinhold-Keller; Elena Csernok; Petra Ambrosch; Bernhard Hellmich; Frank Moosig; Wolfgang L Gross; Hany Sahly; Peter Lamprecht
Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic Rhinosinusitis with nasal polyps.
Clinical and experimental rheumatology 2010;28(1 Suppl 57):51-5.
2010: Julia U Holle; Q J Wu; Frank Moosig; Wolfgang L Gross; Elena Csernok
Membrane proteinase 3 (mPR3) expression on neutrophils is not increased in localized Wegener's granulomatosis (WG) and Churg-Strauss syndrome (CSS).
Clinical and experimental rheumatology 2010;28(1 Suppl 57):46-50.
2010: Claudia Metzler; Elena Csernok; Wolfgang L Gross; Bernhard Hellmich
Interferon-alpha for maintenance of remission in Churg-Strauss syndrome: a long-term observational study.
Clinical and experimental rheumatology 2010;28(1 Suppl 57):24-30.
2010: Elena Csernok; Peter Lamprecht; Wolfgang L Gross
Clinical and immunological features of drug-induced and infection-induced proteinase 3-antineutrophil cytoplasmic antibodies and myeloperoxidase-antineutrophil cytoplasmic antibodies and vasculitis.
Current opinion in rheumatology 2010;22(1):43-8.
2009: Ulrich Sack; Karsten Conrad; Elena Csernok; Ingrid Frank; Falk Hiepe; Thorsten Krieger; Arno Kromminga; Philipp von Landenberg; Gerald Messer; Torsten Witte; Rudolf Mierau
Autoantibody detection using indirect immunofluorescence on HEp-2 cells.
Annals of the New York Academy of Sciences 2009;1173():166-73.
2009: Ulrich Sack; K Conrad; Elena Csernok; I Frank; F Hiepe; T Krieger; A Kromminga; P von Landenberg; G Messer; T Witte; R Mierau
[Autoantibody detection by indirect immunofluorescence on HEp-2 cells].
Deutsche medizinische Wochenschrift (1946) 2009;134(24):1278-82.
2009: René Rückert; Katja Brandt; Martin Ernst; Kathleen Marienfeld; Elena Csernok; Claudia Metzler; Vadim Budagian; Elena Bulanova; Ralf Paus; Silvia Bulfone-Paus
Interleukin-15 stimulates macrophages to activate CD4+ T cells: a role in the pathogenesis of rheumatoid arthritis?
Immunology 2009;126(1):63-73.
2008: Elena Csernok; Frank Moosig; Wolgang L Gross
Pathways to ANCA production: from differentiation of dendritic cells by proteinase 3 to B lymphocyte maturation in Wegener's granuloma.
Clinical reviews in allergy & immunology 2008;34(3):300-6.
2008: Elena Csernok; J U Holle; Wolfgang L Gross
Proteinase 3, protease-activated receptor-2 and interleukin-32: linking innate and autoimmunity in Wegener's granulomatosis.
Clinical and experimental rheumatology 2008;26(3 Suppl 49):S112-7.
2008: Dorin Capraru; Antje Müller; Elena Csernok; Wolfgang L Gross; Konstanze Holl-Ulrich; John Northfield; Paul Klenerman; Karen Herlyn; Julia Holle; Stefan Gottschlich; Jan Voswinkel; Thomas Spies; U Fagin; Wolfram J Jabs; Peter Lamprecht
Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis.
Clinical immunology (Orlando, Fla.) 2008;127(2):144-50.
2007: Antje Müller; Jan Voswinkel; Stefan Gottschlich; Elena Csernok
Human proteinase 3 (PR3) and its binding molecules: implications for inflammatory and PR3-related autoimmune responses.
Annals of the New York Academy of Sciences 2007;1109():84-92.
2007: Ulrich Sack; Karsten Conrad; Elena Csernok; Ingrid Frank; Michael Haass; Thorsten Krieger; Michael Seyfarth; Udo Schlosser; Reinhold E Schmidt; Torsten Witte
Standardization of autoimmune diagnostics in Germany: activities of the German group in the European Autoimmune Standardization Initiative.
Annals of the New York Academy of Sciences 2007;1109():31-6.
2007: Bernhard Hellmich; Elena Csernok; G Fredenhagen; Wolfgang L Gross
A novel high sensitivity ELISA for detection of antineutrophil cytoplasm antibodies against proteinase-3.
Clinical and experimental rheumatology 2007;25(1 Suppl 44):S1-5.
2006: Elena Csernok; Maixing Ai; Wolfgang L Gross; Daniel Wicklein; Arnd Petersen; Buko Lindner; Peter Lamprecht; Julia U Holle; Bernhard Hellmich
Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway.
Blood 2006;107(11):4440-8.
2006: Elena Csernok; Peter Lamprecht; Wolfgang L Gross
Diagnostic significance of ANCA in vasculitis.
Nature clinical practice. Rheumatology 2006;2(4):174-5.
2006: Julia U Holle; Dorin Capraru; Elena Csernok; Wolfgang L Gross; Peter Lamprecht
Expansion of CD28-CD27-NKG2D+ effector memory T cells and predominant Th1-type response during febrile attacks in tumor necrosis factor-associated periodic syndrome.
The Israel Medical Association journal : IMAJ 2006;8(2):142-4.
2006: Paweł Szyld; Peter Jagiello; Elena Csernok; Wolfgang L Gross; Jörg T Epplen
On the Wegener granulomatosis associated region on chromosome 6p21.3.
BMC medical genetics 2006;7():21.
2005: Peter Jagiello; Peer M Aries; Larissa Arning; Sonja E N Wagenleiter; Elena Csernok; Bernhard Hellmich; Wolfgang L Gross; Jörg T Epplen
The PTPN22 620W allele is a risk factor for Wegener's granulomatosis.
Arthritis and rheumatism 2005;52(12):4039-43.
2005: Julia U Holle; Bernhard Hellmich; M Backes; Wolfgang L Gross; Elena Csernok
Variations in performance characteristics of commercial enzyme immunoassay kits for detection of antineutrophil cytoplasmic antibodies: what is the optimal cut off?
Annals of the rheumatic diseases 2005;64(12):1773-9.
2005: Katja Hattar; Sandra van Bürck; Annette Bickenbach; Ulrich Grandel; Ulrich A Maus; Jürgen Lohmeyer; Elena Csernok; Thomas Hartung; Werner Seeger; Friedrich Grimminger; Ulf Sibelius
Anti-proteinase 3 antibodies (c-ANCA) prime CD14-dependent leukocyte activation.
Journal of leukocyte biology 2005;78(4):992-1000.
2005: Bernhard Hellmich; Elena Csernok; Wolfgang L Gross
Proinflammatory cytokines and autoimmunity in Churg-Strauss syndrome.
Annals of the New York Academy of Sciences 2005;1051():121-31.
2005: Peter Jagiello; Wolfram Klein; H Schultz; Elena Csernok; Wolfgang L Gross; Jörg T Epplen
Association study of Wegener granulomatosis and the functionally relevant A645G polymorphism in the bactericidal/permeability increasing protein (BPI) gene.
International journal of immunogenetics 2005;32(1):3-6.
2005: Peter Jagiello; Stefan Wieczorek; Philipp Yu; Elena Csernok; Wolfgang L Gross; Jörg T Epplen
Association study with Wegener granulomatosis of the human phospholipase Cgamma2 gene.
Journal of negative results in biomedicine 2005;4():1.
2004: Sebastian Ullrich; Udo Schumacher; Maixing Ai; Bastian Tiemann; Steffen Gay; Jeffery S Schechner; Jordan S Pober; Wolfgang L Gross; Elena Csernok
Transfer of human leukocytes into double-knockout Pfp-/-Rag2-/- mice grafted with human skin: increased accumulation of neutrophils in human dermal microvessels.
Transplantation 2004;78(10):1557-9.
2004: Peter Lamprecht; Frank Moosig; S Adam-Klages; U Mrowietz; Elena Csernok; M Kirrstetter; Keihan Ahmadi-Simab; J O Schroder; Wolfgang L Gross
Small vessel vasculitis and relapsing panniculitis in tumour necrosis factor receptor associated periodic syndrome (TRAPS).
Annals of the rheumatic diseases 2004;63(11):1518-20.
2004: Katrin S Reiners; Hinrich P Hansen; Anne Krüssmann; Gisela Schön; Elena Csernok; Wolfgang L Gross; Andreas Engert; Elke Pogge Von Strandmann
Selective killing of B-cell hybridomas targeting proteinase 3, Wegener's autoantigen.
Immunology 2004;112(2):228-36.
2004: Peter Jagiello; Martin Gencik; Larissa Arning; Stefan Wieczorek; Erdmute Kunstmann; Elena Csernok; Wolfgang L Gross; Jörg T Epplen
New genomic region for Wegener's granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes.
Human genetics 2004;114(5):468-77.
2004: Jolanta Winek; Antje Mueller; Elena Csernok; Wolfgang L Gross; Peter Lamprecht
Frequency of proteinase 3 (PR3)-specific autoreactive T cells determined by cytokine flow cytometry in Wegener's granulomatosis.
Journal of autoimmunity 2004;22(1):79-85.
2004: Elena Csernok; Julia U Holle; Bernhard Hellmich; Jan Willem; Cohen Tervaert; Cees G M Kallenberg; Peter C Limburg; John Niles; Gouli Pan; Ulrich Specks; Kerstin Westman; Jörgen Wieslander; Kirsten De Groot; Wolfgang L Gross
Evaluation of capture ELISA for detection of antineutrophil cytoplasmic antibodies directed against proteinase 3 in Wegener's granulomatosis: first results from a multicentre study.
Rheumatology (Oxford, England) 2004;43(2):174-80.
2003: Hendrik Schultz; Elena Csernok; Karen Herlyn; Philipp H Reichel; Frank Moosig; O A Cornely; Magne Kristoffer Fagerhol; Wolfgang L Gross
ANCA against bactericidal/permeability-increasing protein, azurocidin, calprotectin and defensins in rheumatic and infectious diseases: prevalence and clinical associations.
Clinical and experimental rheumatology 2003;21(6 Suppl 32):S117-20.
2003: Peter Lamprecht; O Gutzeit; Elena Csernok; Angela Gause; Giovanni Longombardo; Anna Linda Zignego; Wolfgang L Gross; Clodoveo Ferri
Prevalence of ANCA in mixed cryoglobulinemia and chronic hepatitis C virus infection.
Clinical and experimental rheumatology 2003;21(6 Suppl 32):S89-94.
2003: Bernhard Hellmich; S Ehlers; Elena Csernok; Wolfgang L Gross
Update on the pathogenesis of Churg-Strauss syndrome.
Clinical and experimental rheumatology 2003;21(6 Suppl 32):S69-77.
2003: Peter Lamprecht; Ana L Vargas Cuero; Antje Muller; Elena Csernok; Jan Voswinkel; Matthias Maass; Werner Solbach; Wolfgang L Gross; Paul Klenerman
Alterations in the phenotype of CMV-specific and total CD8+ T-cell populations in Wegener's granulomatosis.
Cellular immunology 2003;224(1):1-7.
2003: Peter Lamprecht; Hilke Bruhl; Anika Erdmann; Konstanze Holl-Ulrich; Elena Csernok; Ulrike Seitzer; Matthias Mack; Alfred C Feller; Eva Reinhold-Keller; Wolfgang L Gross; Antje Muller
Differences in CCR5 expression on peripheral blood CD4+CD28- T-cells and in granulomatous lesions between localized and generalized Wegener's granulomatosis.
Clinical immunology (Orlando, Fla.) 2003;108(1):1-7.
2003: Bernhard Hellmich; Elena Csernok; Wolfgang L Gross
20 years with ANCA (antineutrophil cytoplasmic autoantibodies): from seromarker to a major pathogenic player in vasculitis.
Journal of leukocyte biology 2003;74(1):1-2.
2003: Elena Csernok
Anti-neutrophil cytoplasmic antibodies and pathogenesis of small vessel vasculitides.
Autoimmunity reviews 2003;2(3):158-64.
2003: Philipp H Reichel; Christine Seemann; Elena Csernok; Jens Schröder; Antje Müller; Wolfgang L Gross; Hendrik Schultz
Bactericidal/permeability-increasing protein is expressed by human dermal fibroblasts and upregulated by interleukin 4.
Clinical and diagnostic laboratory immunology 2003;10(3):473-5.
2003: Peter Lamprecht; Anika Erdmann; Antje Mueller; Elena Csernok; Eva Reinhold-Keller; Konstanze Holl-Ulrich; Alfred C Feller; Hilke Bruehl; Wolfgang L Gross
Heterogeneity of CD4 and CD8+ memory T cells in localized and generalized Wegener's granulomatosis.
Arthritis research & therapy 2003;5(1):R25-31.
2002: Elena Csernok; D Ahlquist; S Ullrich; Wolfgang L Gross
A critical evaluation of commercial immunoassays for antineutrophil cytoplasmic antibodies directed against proteinase 3 and myeloperoxidase in Wegener's granulomatosis and microscopic polyangiitis.
Rheumatology (Oxford, England) 2002;41(11):1313-7.
2002: Bernhard Hellmich; Elena Csernok; Helmut Schatz; Wolfgang L Gross; Armin Schnabel
Autoantibodies against granulocyte colony-stimulating factor in Felty's syndrome and neutropenic systemic lupus erythematosus.
Arthritis and rheumatism 2002;46(9):2384-91.
2002: Elena Csernok; Philipp H Reichel; Wolfgang L Gross
[New aspects of antineutrophil cytoplasmic antibody (ANCA) diagnosis in vasculitis].
Zeitschrift für Rheumatologie 2002;61(4):367-77.
2002: Bernhard Hellmich; Elena Csernok; Masja de Haas; Albert E G K R von dem Borne; Helmut Schatz; Wolfgang L Gross; Armin Schnabel
Low Fcgamma receptor III and high granulocyte colony-stimulating factor serum levels correlate with the risk of infection in neutropenia due to Felty's syndrome or systemic lupus erythematosus.
The American journal of medicine 2002;113(2):134-9.
2002: Katja Hattar; Annette Bickenbach; Elena Csernok; Simone Rosseau; Ulrich Grandel; Werner Seeger; Friedrich Grimminger; Ulf Sibelius
Wegener's granulomatosis: antiproteinase 3 antibodies induce monocyte cytokine and prostanoid release-role of autocrine cell activation.
Journal of leukocyte biology 2002;71(6):996-1004.
2002: Karen Maehnss; Jörg Kobarg; Wilhelm H Schmitt; Hinrich P Hansen; Hans Lange; Elena Csernok; Wolfgang L Gross; Hilmar Lemke
Vitronectin- and fibronectin-containing immune complexes in primary systemic vasculitis.
Journal of autoimmunity 2002;18(3):239-50.
2002: Andras Komocsi; Peter Lamprecht; Elena Csernok; Antje Mueller; Konstanze Holl-Ulrich; Ulrike Seitzer; Frank Moosig; Armin Schnabel; Wolfgang L Gross
Peripheral blood and granuloma CD4(+)CD28(-) T cells are a major source of interferon-gamma and tumor necrosis factor-alpha in Wegener's granulomatosis.
The American journal of pathology 2002;160(5):1717-24.
2002: Peter Lamprecht; G Kumanovics; Antje Mueller; Elena Csernok; Andras Komocsi; A Trabandt; Wolfgang L Gross; Armin Schnabel
Elevated monocytic IL-12 and TNF-alpha production in Wegener's granulomatosis is normalized by cyclophosphamide and corticosteroid therapy.
Clinical and experimental immunology 2002;128(1):181-6.
2001: K Steiner; Frank Moosig; Elena Csernok; Kathleen Selleng; Wolfgang L Gross; Bernhard Fleischer; Barbara M Bröker
Increased expression of CTLA-4 (CD152) by T and B lymphocytes in Wegener's granulomatosis.
Clinical and experimental immunology 2001;126(1):143-50.
2001: Peter Lamprecht; Frank Moosig; Elena Csernok; Ulrike Seitzer; Armin Schnabel; Antje Mueller; Wolfgang L Gross
CD28 negative T cells are enriched in granulomatous lesions of the respiratory tract in Wegener's granulomatosis.
Thorax 2001;56(10):751-7.
2001: J Rautenstrauch; Angela Gause; Elena Csernok; J Holle; Wolfgang L Gross
[Presentation of the Lubeck/Bad Bramstedt Competence Center].
Zeitschrift für Rheumatologie 2001;60(4):255-62.
2001: Peter Lamprecht; Frank Moosig; Angela Gause; Karen Herlyn; Elena Csernok; H Hansen; Wolfgang L Gross
Immunological and clinical follow up of hepatitis C virus associated cryoglobulinaemic vasculitis.
Annals of the rheumatic diseases 2001;60(4):385-90.
2001: Ulf Schönermarck; Peter Lamprecht; Elena Csernok; Wolfgang L Gross
Prevalence and spectrum of rheumatic diseases associated with proteinase 3-antineutrophil cytoplasmic antibodies (ANCA) and myeloperoxidase-ANCA.
Rheumatology (Oxford, England) 2001;40(2):178-84.
2001: M Kiene; Elena Csernok; Antje Müller; C Metzler; A Trabandt; Wolfgang L Gross
Elevated interleukin-4 and interleukin-13 production by T cell lines from patients with Churg-Strauss syndrome.
Arthritis and rheumatism 2001;44(2):469-73.
2001: Katja Hattar; Ulf Sibelius; Annette Bickenbach; Elena Csernok; Werner Seeger; Friedrich Grimminger
Subthreshold concentrations of anti-proteinase 3 antibodies (c-ANCA) specifically prime human neutrophils for fMLP-induced leukotriene synthesis and chemotaxis.
Journal of leukocyte biology 2001;69(1):89-97.
2000: Frank Moosig; Elena Csernok; G Kumanovics; Wolfgang L Gross
Opsonization of apoptotic neutrophils by anti-neutrophil cytoplasmic antibodies (ANCA) leads to enhanced uptake by macrophages and increased release of tumour necrosis factor-alpha (TNF-alpha).
Clinical and experimental immunology 2000;122(3):499-503.
2000: Elena Csernok; Wolfgang L Gross
Primary vasculitides and vasculitis confined to skin: clinical features and new pathogenic aspects.
Archives of dermatological research 2000;292(9):427-36.
2000: Antje Müller; A Trabandt; K Gloeckner-Hofmann; Ulrike Seitzer; Elena Csernok; Ulf Schönermarck; Alfred C Feller; Wolfgang L Gross
Localized Wegener's granulomatosis: predominance of CD26 and IFN-gamma expression.
The Journal of pathology 2000;192(1):113-20.
2000: Ulf Schönermarck; Elena Csernok; A Trabandt; H Hansen; Wolfgang L Gross
Circulating cytokines and soluble CD23, CD26 and CD30 in ANCA-associated vasculitides.
Clinical and experimental rheumatology 2000;18(4):457-63.
2000: Hendrik Schultz; Elena Csernok; Antje Schuster; Thomas Schmitz; M Ernst; Wolfgang L Gross
Anti-neutrophil cytoplasmic antibodies directed against the bactericidal/permeability-increasing protein (BPI) in pediatric cystic fibrosis patients do not recognize N-terminal regions important for the anti-microbial and lipopolysaccharide-binding activity of BPI.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2000;11(2):64-70.
2000: Bernhard Hellmich; Elena Csernok; A Trabandt; Wolfgang L Gross; M Ernst
Granulocyte-macrophage colony-stimulating factor (GM-CSF) but not granulocyte colony-stimulating factor (G-CSF) induces plasma membrane expression of proteinase 3 (PR3) on neutrophils in vitro.
Clinical and experimental immunology 2000;120(2):392-8.
2000: Armin Schnabel; Elena Csernok; Jörg Braun; Wolfgang L Gross
Activation of neutrophils, eosinophils, and lymphocytes in the lower respiratory tract in Wegener's granulomatosis.
American journal of respiratory and critical care medicine 2000;161(2 Pt 1):399-405.
2000: Hendrik Schultz; Elena Csernok; Seppo T Nikkari; Paavo Toivanen; Auli Toivanen; Wolfgang L Gross
BPI-ANCA is found in reactive arthritis caused by Yersinia and Salmonella infection and recognise exclusively the C-terminal part of the BPI molecule.
Scandinavian journal of rheumatology 2000;29(4):226-31.
1999: Armin Schnabel; Michael Reuter; Elena Csernok; C Richter; Wolfgang L Gross
Subclinical alveolar bleeding in pulmonary vasculitides: correlation with indices of disease activity.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(1):118-24.
1999: Armin Schnabel; H Renz; R Petermann; Elena Csernok; Wolfgang L Gross
T cell receptor vbeta repertoire in bronchoalveolar lavage in Wegener's granulomatosis and sarcoidosis.
International archives of allergy and immunology 1999;119(3):223-30.
1999: Elena Csernok; A Trabandt; Antje Müller; G C Wang; Frank Moosig; J Paulsen; Armin Schnabel; Wolfgang L Gross
Cytokine profiles in Wegener's granulomatosis: predominance of type 1 (Th1) in the granulomatous inflammation.
Arthritis and rheumatism 1999;42(4):742-50.
1998: Frank Moosig; Elena Csernok; G Wang; Wolfgang L Gross
Costimulatory molecules in Wegener's granulomatosis (WG): lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells.
Clinical and experimental immunology 1998;114(1):113-8.
1998: Wolfgang L Gross; A Trabandt; Elena Csernok
Pathogenesis of Wegener's granulomatosis.
Annales de médecine interne 1998;149(5):280-6.
1998: Frank Moosig; Elena Csernok; Eva Reinhold-Keller; WH Schmitt; Wolfgang L Gross
Elevated procalcitonin levels in active Wegener's granulomatosis.
The Journal of rheumatology 1998;25(8):1531-3.
1998: Frank Moosig; Eva Reinhold-Keller; Elena Csernok; Wolfgang L Gross
Limitations on the usefulness of procalcitonin as a marker of infection in patients with systemic autoimmune disease: comment on the article by Eberhard et al.
Arthritis and rheumatism 1998;41(3):566-7; author reply 568.
1998: WH Schmitt; Elena Csernok; S Kobayashi; A Klinkenborg; Eva Reinhold-Keller; Wolfgang L Gross
Churg-Strauss syndrome: serum markers of lymphocyte activation and endothelial damage.
Arthritis and rheumatism 1998;41(3):445-52.
1998: Ulf Sibelius; Katja Hattar; A Schenkel; Thomas Noll; Elena Csernok; W L Gross; Werner-Johannes Mayet; Hans Michael Piper; Werner Seeger; Friedrich Grimminger
Wegener's granulomatosis: anti-proteinase 3 antibodies are potent inductors of human endothelial cell signaling and leakage response.
The Journal of experimental medicine 1998;187(4):497-503.
1997: G Wang; Elena Csernok; Kirsten De Groot; Wolfgang L Gross
Comparison of eight commercial kits for quantitation of antineutrophil cytoplasmic antibodies (ANCA).
Journal of immunological methods 1997;208(2):203-11.
1997: Armin Schnabel; Elena Csernok; Hendrik Schultz; M Stoffel; C Herzberg; S F Carroll; Wolfgang L Gross
[Bactericidal permeability increasing protein (BPI-ANCA marked chronic inflammatory bowel diseases and hepatobiliary diseases].
Medizinische Klinik (Munich, Germany : 1983) 1997;92(7):389-93.
1997: Hendrik Schultz; Elena Csernok; T W Johnston; C M Lockwood; Wolfgang L Gross
Use of native and recombinant bactericidal/permeability-increasing proteins (BPI) as antigens for detection of BPI-ANCA.
Journal of immunological methods 1997;205(2):127-33.
1997: G Wang; H Hansen; E Tatsis; Elena Csernok; H Lemke; Wolfgang L Gross
High plasma levels of the soluble form of CD30 activation molecule reflect disease activity in patients with Wegener's granulomatosis.
The American journal of medicine 1997;102(6):517-23.
1997: Beate Mascher; WH Schmitt; Elena Csernok; E Tatsis; Angelika Reil; Wolfgang L Gross; Michael Seyfarth
Polymorphisms in the tumor necrosis factor genes in Wegener's granulomatosis.
Experimental and clinical immunogenetics 1997;14(3):226-33.
1997: Elena Csernok; A Trabandt; Wolfgang L Gross
Immunogenetic aspects of ANCA-associated vasculitides. Editorial overview.
Experimental and clinical immunogenetics 1997;14(3):177-82.
1997: H P Strunz; Elena Csernok; Wolfgang L Gross
Incidence and disease associations of a proteinase 3-antineutrophil cytoplasmic antibody idiotype (5/7 Id) whose antiidiotype inhibits proteinase 3-antineutrophil cytoplasmic antibody antigen binding activity.
Arthritis and rheumatism 1997;40(1):135-42.
1996: J D Weinerth; M P Stoffel; Elena Csernok; W L Gross
Are antineutrophil cytoplasmic antibodies associated with spondyloarthropathies?
British journal of rheumatology 1996;35(10):1032-3.
1996: Chris Hagen; K Andrassy; Elena Csernok; Mohamed R Daha; G Gaskin; Wolfgang L Gross; B Hansen; Z Heigl; J Hermans; David Jayne; Cees G M Kallenberg; P Lesavre; CM Lockwood; J Lüdemann; F Mascart-Lemone; E Mirapeix; C D Pusey; N Rasmussen; renato alberto sinico; A Tzioufas; Jörgen Wieslander; Allan Wiik; Fokko J van der Woude
Development and standardization of solid phase assays for the detection of anti-neutrophil cytoplasmic antibodies (ANCA). A report on the second phase of an international cooperative study on the standardization of ANCA assays.
Journal of immunological methods 1996;196(1):1-15.
1996: M P Stoffel; Elena Csernok; W L Gross
Target antigen for anti-neutrophil cytoplasmic antibodies in inflammatory bowel disease.
Scandinavian journal of gastroenterology 1996;31(9):943-4.
1996: M P Stoffel; Elena Csernok; W L Gross
Are antineutrophil cytoplasmic antibodies of immunodiagnostic value in reactive arthritis?
The Journal of rheumatology 1996;23(9):1670-2.
1996: Elena Csernok; C H Szymkowiak; N Mistry; M R Daha; Wolfgang L Gross; Jörn Kekow
Transforming growth factor-beta (TGF-beta) expression and interaction with proteinase 3 (PR3) in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis.
Clinical and experimental immunology 1996;105(1):104-11.
1996: M G Braun; Elena Csernok; W Rögener-Schwarz; W D Ludwig; Hans Konrad Müller-Hermelink; Wolfgang L Gross; Alfred C Feller
Monoclonal antibody WGM1 directed against proteinase 3: an immunohistochemical marker for naphthol ASD chloroacetate.
Hematological oncology 1996;14(2):83-90.
1996: M G Braun; Elena Csernok; WH Schmitt; Wolfgang L Gross
Incidence, target antigens, and clinical implications of antineutrophil cytoplasmic antibodies in rheumatoid arthritis.
The Journal of rheumatology 1996;23(5):826-30.
1996: M P Stoffel; Elena Csernok; C Herzberg; T Johnson; S F Carroll; Wolfgang L Gross
Anti-neutrophil cytoplasmic antibodies (ANCA) directed against bactericidal/permeability increasing protein (BPI): a new seromarker for inflammatory bowel disease and associated disorders.
Clinical and experimental immunology 1996;104(1):54-9.
1996: C H Szymkowiak; T W Johnston; Elena Csernok; Wolfgang L Gross
Expression of the human autoantigen of Wegener's granulomatosis (PR3) in a baculovirus expression system.
Biochemical and biophysical research communications 1996;219(2):283-9.
1995: C Richter; Armin Schnabel; Elena Csernok; Kirsten De Groot; Eva Reinhold-Keller; Wolfgang L Gross
Treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis with high-dose intravenous immunoglobulin.
Clinical and experimental immunology 1995;101(1):2-7.
1995: Armin Schnabel; Elena Csernok; D A Isenberg; C Mrowka; Wolfgang L Gross
Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus. Prevalence, specificities, and clinical significance.
Arthritis and rheumatism 1995;38(5):633-7.
1995: C Mrowka; Elena Csernok; Wolfgang L Gross; HE Feucht; U Bechtel; G H Thoenes
Distribution of the granulocyte serine proteinases proteinase 3 and elastase in human glomerulonephritis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1995;25(2):253-61.
1995: Wolfgang L Gross; Elena Csernok; U Helmchen
Antineutrophil cytoplasmic autoantibodies, autoantigens, and systemic vasculitis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1995;103(2):81-97.
1995: Wolfgang L Gross; Elena Csernok
Immunodiagnostic and pathophysiologic aspects of antineutrophil cytoplasmic antibodies in vasculitis.
Current opinion in rheumatology 1995;7(1):11-9.
1994: S Hauschild; Elena Csernok; WH Schmitt; Wolfgang L Gross
Antineutrophil cytoplasmic antibodies in systemic polyarteritis nodosa with and without hepatitis B virus infection and Churg-Strauss syndrome--62 patients.
The Journal of rheumatology 1994;21(6):1173-4.
1994: Elena Csernok; M Ernst; WH Schmitt; D F Bainton; Wolfgang L Gross
Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo.
Clinical and experimental immunology 1994;95(2):244-50.
1993: Werner-Johannes Mayet; Elena Csernok; C Szymkowiak; Wolfgang L Gross; K H Meyer zum Büschenfelde
Human endothelial cells express proteinase 3, the target antigen of anticytoplasmic antibodies in Wegener's granulomatosis.
Blood 1993;82(4):1221-9.
1993: Wolfgang L Gross; Elena Csernok; B K Flesch
'Classic' anti-neutrophil cytoplasmic autoantibodies (cANCA), 'Wegener's autoantigen' and their immunopathogenic role in Wegener's granulomatosis.
Journal of autoimmunity 1993;6(2):171-84.
1993: Jörn Kekow; Elena Csernok; C H Szymkowiak; Wolfgang L Gross
[Wegener's granulomatosis and ANCA-associated vasculitis: pathogenic role of autoantigens, autoantibodies, and cytokines].
Immunität und Infektion 1993;21 Suppl 1():44-8.
1993: Wolfgang L Gross; WH Schmitt; Elena Csernok
ANCA and associated diseases: immunodiagnostic and pathogenetic aspects.
Clinical and experimental immunology 1993;91(1):1-12.
1993: C Richter; Armin Schnabel; Elena Csernok; Eva Reinhold-Keller; Wolfgang L Gross
Treatment of Wegener's granulomatosis with intravenous immunoglobulin.
Advances in experimental medicine and biology 1993;336():487-9.
1993: Elena Csernok; WH Schmitt; M Ernst; D F Bainton; Wolfgang L Gross
Membrane surface proteinase 3 expression and intracytoplasmic immunoglobulin on neutrophils from patients with ANCA-associated vasculitides.
Advances in experimental medicine and biology 1993;336():45-50.
1993: M G Braun; Elena Csernok; WH Schmitt; Wolfgang L Gross
Incidence and specificity of p-ANCA in rheumatic diseases.
Advances in experimental medicine and biology 1993;336():371-3.
1993: WH Schmitt; Elena Csernok; B K Flesch; S Hauschild; Wolfgang L Gross
Autoantibodies directed against lysozyme: a new target antigen for anti-neutrophil cytoplasmic antibodies (ANCA).
Advances in experimental medicine and biology 1993;336():267-72.
1993: S Hauschild; WH Schmitt; Elena Csernok; B K Flesch; A Rautmann; Wolfgang L Gross
ANCA in systemic vasculitides, collagen vascular diseases, rheumatic disorders and inflammatory bowel diseases.
Advances in experimental medicine and biology 1993;336():245-51.
1993: Werner-Johannes Mayet; E M Hermann; Elena Csernok; Wolfgang L Gross; K H Meyer zum Büschenfelde
In vitro interactions of c-ANCA (antibodies to proteinase 3) with human endothelial cells.
Advances in experimental medicine and biology 1993;336():109-13.
1993: M Schwarz-Eywill; A Breitbart; Elena Csernok; Antonio Pezzutto; Wolfgang L Gross
Treatment modalities and ANCA in Takayasu's arteritis.
Advances in experimental medicine and biology 1993;336():497-501.
1992: WH Schmitt; C Heesen; Elena Csernok; A Rautmann; Wolfgang L Gross
Elevated serum levels of soluble interleukin-2 receptor in patients with Wegener's granulomatosis. Association with disease activity.
Arthritis and rheumatism 1992;35(9):1088-96.
1991: M G Braun; Elena Csernok; Wolfgang L Gross; Hans Konrad Müller-Hermelink
Proteinase 3, the target antigen of anticytoplasmic antibodies circulating in Wegener's granulomatosis. Immunolocalization in normal and pathologic tissues.
The American journal of pathology 1991;139(4):831-8.
1991: Werner-Johannes Mayet; E Hermann; Elena Csernok; A Knuth; T Poralla; Wolfgang L Gross; K H Meyer zum Büschenfelde
A human renal cancer line as a new antigen source for the detection of antibodies to cytoplasmic and nuclear antigens in sera of patients with Wegener's granulomatosis.
Journal of immunological methods 1991;143(1):57-68.
1991: Wolfgang L Gross; Elena Csernok; WH Schmitt
Antineutrophil cytoplasmic autoantibodies: immunobiological aspects.
Klinische Wochenschrift 1991;69(13):558-66.
1991: Wolfgang L Gross; WH Schmitt; Elena Csernok
Antineutrophil cytoplasmic autoantibody-associated diseases: a rheumatologist's perspective.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1991;18(2):175-9.
1991: M G Braun; Elena Csernok; Hans Konrad Müller-Hermelink; Wolfgang L Gross
[Distribution pattern of proteinase 3 in Wegener's granulomatosis and other vasculitic diseases].
Immunität und Infektion 1991;19(1):23-4.
1991: Wolfgang L Gross; Elena Csernok; Jörn Kekow
[Growth factors and cytokines in the pathogenesis of systemic vasculitis].
Verhandlungen der Deutschen Gesellschaft für Innere Medizin 1991;97():469-77.
1990: Elena Csernok; J Lüdemann; Wolfgang L Gross; D F Bainton
Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis.
The American journal of pathology 1990;137(5):1113-20.
1990: J Lüdemann; Elena Csernok; M Ulmer; H Lemke; B Utecht; A Rautmann; Wolfgang L Gross
Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis: immunodiagnostic value, monoclonal antibodies and characterization of the target antigen.
The Netherlands journal of medicine 1990;36(3-4):157-62.