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Paola Cucchi

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stefania meini; S Niccolini; Laura Tinti; Claudio Valenti; Francesca Bellucci; Claudio Catalani; Paola Cucchi; A Fioravanti; Mauro Galeazzi; Carlo Alberto Maggi
Fasitibant prevents the bradykinin and interleukin 1β synergism on prostaglandin E₂ release and cyclooxygenase 2 expression in human fibroblast-like synoviocytes.
stefania meini; Paola Cucchi; Claudio Catalani; Francesca Bellucci; Sandro Giuliani; Carlo Alberto Maggi
Bradykinin and B₂ receptor antagonism in rat and human articular chondrocytes.
stefania meini; Paola Cucchi; Claudio Catalani; Francesca Bellucci; Paolo Santicioli; Sandro Giuliani; Carlo Alberto Maggi
Radioligand binding characterization of the bradykinin B(2) receptor in the rabbit and pig ileal smooth muscle.

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All Publications

2012: stefania meini; S Niccolini; Laura Tinti; Claudio Valenti; Francesca Bellucci; Claudio Catalani; Paola Cucchi; A Fioravanti; Mauro Galeazzi; Carlo Alberto Maggi
Fasitibant prevents the bradykinin and interleukin 1β synergism on prostaglandin E₂ release and cyclooxygenase 2 expression in human fibroblast-like synoviocytes.
Naunyn-Schmiedeberg's archives of pharmacology 2012;385(8):777-86.
2011: stefania meini; Paola Cucchi; Claudio Catalani; Francesca Bellucci; Sandro Giuliani; Carlo Alberto Maggi
Bradykinin and B₂ receptor antagonism in rat and human articular chondrocytes.
British journal of pharmacology 2011;162(3):611-22.
2010: stefania meini; Paola Cucchi; Claudio Catalani; Francesca Bellucci; Paolo Santicioli; Sandro Giuliani; Carlo Alberto Maggi
Radioligand binding characterization of the bradykinin B(2) receptor in the rabbit and pig ileal smooth muscle.
European journal of pharmacology 2010;635(1-3):34-9.
2009: Francesca Bellucci; Paola Cucchi; Claudio Catalani; Sandro Giuliani; stefania meini; Carlo Alberto Maggi
Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B2 receptor antagonism in human synovial fibroblasts.
British journal of pharmacology 2009;158(8):1996-2004.
2007: Steven Ballet; R De Wachter; Karolien Van Rompaey; Csaba Tömböly; D Feytens; G Töth; Laura Quartara; Paola Cucchi; stefania meini; Dirk Tourwé
Bradykinin analogs containing the 4-amino-2-benzazepin-3-one scaffold at the C-terminus.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(3):164-70.
2007: stefania meini; Paola Cucchi; Francesca Bellucci; Claudio Catalani; Sandro Giuliani; Paolo Santicioli; Carlo Alberto Maggi
Comparative antagonist pharmacology at the native mouse bradykinin B2 receptor: radioligand binding and smooth muscle contractility studies.
British journal of pharmacology 2007;150(3):313-20.
2007: Francesca Bellucci; Paola Cucchi; Paolo Santicioli; Massimo Lazzeri; Damiano Turini; stefania meini
Characterization of kinin receptors in human cultured detrusor smooth muscle cells.
British journal of pharmacology 2007;150(2):192-9.
2005: Paola Cucchi; stefania meini; Alessandro Bressan; Claudio Catalani; Francesca Bellucci; Paolo Santicioli; Alessandro Lecci; Angela Faiella; Luigi Rotondaro; Sandro Giuliani; Alessandro Giolitti; Laura Quartara; Carlo Alberto Maggi
MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization.
European journal of pharmacology 2005;528(1-3):7-16.
2005: stefania meini; Claudio Catalani; Francesca Bellucci; Paola Cucchi; Sandro Giuliani; Sabrina Zappitelli; Luigi Rotondaro; Franco Pasqui; Antonio Guidi; Maria Altamura; Alessandro Giolitti; Carlo Alberto Maggi
Pharmacology of an original and selective nonpeptide antagonist ligand for the human tachykinin NK2 receptor.
European journal of pharmacology 2005;516(2):104-11.
2004: stefania meini; Francesca Bellucci; Paola Cucchi; Sandro Giuliani; Laura Quartara; Alessandro Giolitti; Sabrina Zappitelli; Luigi Rotondaro; Katrin Boels; Carlo Alberto Maggi
Bradykinin B2 and GPR100 receptors: a paradigm for receptor signal transduction pharmacology.
British journal of pharmacology 2004;143(8):938-41.
2004: Francesca Bellucci; stefania meini; Paola Cucchi; Claudio Catalani; Sandro Giuliani; Sabrina Zappitelli; Luigi Rotondaro; Laura Quartara; Alessandro Giolitti; Carlo Alberto Maggi
The N-terminal of icatibant and bradykinin interact with the same Asp residues in the human B2 receptor.
European journal of pharmacology 2004;491(2-3):121-5.
2004: stefania meini; Francesca Bellucci; Claudio Catalani; Paola Cucchi; Riccardo Patacchini; Luigi Rotondaro; Maria Altamura; Sandro Giuliani; Alessandro Giolitti; Carlo Alberto Maggi
Mutagenesis at the human tachykinin NK(2) receptor to define the binding site of a novel class of antagonists.
European journal of pharmacology 2004;488(1-3):61-9.
2004: stefania meini; Paola Cucchi; Francesca Bellucci; Claudio Catalani; Angela Faiella; Luigi Rotondaro; Laura Quartara; Alessandro Giolitti; Carlo Alberto Maggi
Site-directed mutagenesis at the human B2 receptor and molecular modelling to define the pharmacophore of non-peptide bradykinin receptor antagonists.
Biochemical pharmacology 2004;67(4):601-9.
2003: Francesca Bellucci; stefania meini; Paola Cucchi; Claudio Catalani; Wolfgang Reichert; Sabrina Zappitelli; Luigi Rotondaro; Laura Quartara; Alessandro Giolitti; Carlo Alberto Maggi
A different molecular interaction of bradykinin and the synthetic agonist FR190997 with the human B2 receptor: evidence from mutational analysis.
British journal of pharmacology 2003;140(3):500-6.
2002: Francesc Cabré; Assumpta Carabaza; Ana Maria García; Lidia Calvo; Paola Cucchi; Albert Palomer; Jaume Pascual; Maria Lluisa García; Stefano Manzini; Alessandro Lecci; Attilio Crea; Carlo Alberto Maggi
Pharmacological profile of MEN91507, a new CysLT(1) receptor antagonist.
European journal of pharmacology 2002;451(3):317-26.
2002: Paola Cucchi; stefania meini; Laura Quartara; Alessandro Giolitti; Sabrina Zappitelli; Luigi Rotondaro; Carlo Alberto Maggi
Interaction of linear and cyclic peptide antagonists at the human B(2) kinin receptor.
Peptides 2002;23(8):1457-63.
2002: stefania meini; Paola Cucchi; Sabrina Zappitelli; Luigi Rotondaro; Laura Quartara; Alessandro Giolitti; Carlo Alberto Maggi
Preliminary mutational analysis of the human kinin B2 receptor for nonpeptide antagonist ligands recognition.
Canadian journal of physiology and pharmacology 2002;80(4):303-9.
2002: Francesca Bellucci; Francesca Carini; Claudio Catalani; Paola Cucchi; Alessandro Lecci; stefania meini; Riccardo Patacchini; Laura Quartara; Renzo Ricci; Manuela Tramontana; Sandro Giuliani; Carlo Alberto Maggi
Pharmacological profile of the novel mammalian tachykinin, hemokinin 1.
British journal of pharmacology 2002;135(1):266-74.
2000: Alessandro Giolitti; Paola Cucchi; Anna-Rita Renzetti; Luigi Rotondaro; Sabrina Zappitelli; Carlo Alberto Maggi
Molecular determinants of peptide and nonpeptide NK-2 receptor antagonists binding sites of the human tachykinin NK-2 receptor by site-directed mutagenesis.
Neuropharmacology 2000;39(8):1422-9.
1999: Anna-Rita Renzetti; Rose-Marie Catalioto; Marco Criscuoli; Paola Cucchi; C Ferrer; Alessandro Giolitti; M Guelfi; Luigi Rotondaro; F J Warner; Carlo Alberto Maggi
Relevance of aromatic residues in transmembrane segments V to VII for binding of peptide and nonpeptide antagonists to the human tachykinin NK(2) receptor.
The Journal of pharmacology and experimental therapeutics 1999;290(2):487-95.
1999: stefania meini; Laura Quartara; Anna Rizzi; Riccardo Patacchini; Paola Cucchi; Alessandro Giolitti; G Calò; Domenico Regoli; Marco Criscuoli; Carlo Alberto Maggi
MEN 11270, A novel selective constrained peptide antagonist with high affinity at the human B2 kinin receptor.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1250-6.
1999: Anna-Rita Renzetti; Rose-Marie Catalioto; C Carloni; Marco Criscuoli; Paola Cucchi; Alessandro Giolitti; Sabrina Zappitelli; Luigi Rotondaro; Carlo Alberto Maggi
Defects of tyrosine289phenylalanine mutation on binding and functional properties of the human tachykinin NK2 receptor stably expressed in chinese hamster ovary cells.
Biochemical pharmacology 1999;57(8):899-906.
1998: Rose-Marie Catalioto; Paola Cucchi; Anna-Rita Renzetti; Marco Criscuoli; Carlo Alberto Maggi
Independent coupling of the human tachykinin NK2 receptor to phospholipases C and A2 in transfected Chinese hamster ovary cells.
Naunyn-Schmiedeberg's archives of pharmacology 1998;358(4):395-403.
1998: stefania meini; Alessandro Lecci; Paola Cucchi; Rose-Marie Catalioto; Marco Criscuoli; Carlo Alberto Maggi
Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists.
The Journal of pharmacology and experimental therapeutics 1998;287(1):137-43.
1998: Anna-Rita Renzetti; Rose-Marie Catalioto; Marco Criscuoli; Paola Cucchi; Alma Lippi; M Guelfi; Laura Quartara; Carlo Alberto Maggi
Characterization of [3H]MEN 11420, a novel glycosylated peptide antagonist radioligand of the tachykinin NK2 receptor.
Biochemical and biophysical research communications 1998;248(1):78-82.
1998: Rose-Marie Catalioto; Marco Criscuoli; Paola Cucchi; A Giachetti; D Gianotti; Sandro Giuliani; Alessandro Lecci; Alma Lippi; Riccardo Patacchini; Laura Quartara; Anna-Rita Renzetti; Manuela Tramontana; F Arcamone; Carlo Alberto Maggi
MEN 11420 (Nepadutant), a novel glycosylated bicyclic peptide tachykinin NK2 receptor antagonist.
British journal of pharmacology 1998;123(1):81-91.
1997: Carlo Alberto Maggi; Rose-Marie Catalioto; Marco Criscuoli; Paola Cucchi; Sandro Giuliani; Alessandro Lecci; Alma Lippi; stefania meini; Riccardo Patacchini; Anna-Rita Renzetti; Paolo Santicioli; Manuela Tramontana; V Zagorodnyuk; A Giachetti
Tachykinin receptors and intestinal motility.
Canadian journal of physiology and pharmacology 1997;75(6):696-703.
1996: Rose-Marie Catalioto; Paola Cucchi; Anna-Rita Renzetti; Marco Criscuoli; A Subissi
Human umbilical vein smooth muscle cells as a model to study thrombin generation and function: effect of thrombin inhibitors.
Thrombosis and haemostasis 1996;76(4):603-9.
1995: Anna-Rita Renzetti; Paola Cucchi; M Guelfi; R Cirillo; A Salimbeni; A Subissi; A Giachetti
Pharmacology of LR-B/057, a novel orally active AT1 receptor antagonist.
Journal of cardiovascular pharmacology 1995;25(3):354-60.
1995: R Cirillo; Anna-Rita Renzetti; Paola Cucchi; M Guelfi; A Salimbeni; S Caliari; A Castellucci; Stefano Evangelista; A Subissi; A Giachetti
Pharmacology of LR-B/081, a new highly potent, selective and orally active, nonpeptide angiotensin II AT1 receptor antagonist.
British journal of pharmacology 1995;114(6):1117-24.
1993: A Eglezos; Paola Cucchi; Riccardo Patacchini; Laura Quartara; Carlo Alberto Maggi; J Mizrahi
Differential effects of BQ-123 against endothelin-1 and endothelin-3 on the rat vas deferens: evidence for an atypical endothelin receptor.
British journal of pharmacology 1993;109(3):736-8.