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José Almendral

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Parvoviridae Infections

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Cristina Sánchez-Martínez; Miles Carroll; Esther Grueso; Jean Rommelaere; José M Almendral
Essential role of the unordered VP2 n-terminal domain of the parvovirus MVM capsid in nuclear assembly and endosomal enlargement of the virion fivefold channel for cell entry.
Dieuwke Engelsma; Noelia Valle; Alexander Fish; Nathalie Salomé; José M Almendral; Maarten Fornerod
A supraphysiological nuclear export signal is required for parvovirus nuclear export.
Alberto López-Bueno; Jose C Segovia; Juan A. Bueren; M Gerard O'Sullivan; Feng Wang; Peter Tattersall; José M Almendral
Evolution to pathogenicity of the parvovirus minute virus of mice in immunodeficient mice involves genetic heterogeneity at the capsid domain that determines tropism.

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All Publications

2012: Cristina Sánchez-Martínez; Miles Carroll; Esther Grueso; Jean Rommelaere; José M Almendral
Essential role of the unordered VP2 n-terminal domain of the parvovirus MVM capsid in nuclear assembly and endosomal enlargement of the virion fivefold channel for cell entry.
Virology 2012;432(1):45-56.
2008: Dieuwke Engelsma; Noelia Valle; Alexander Fish; Nathalie Salomé; José M Almendral; Maarten Fornerod
A supraphysiological nuclear export signal is required for parvovirus nuclear export.
Molecular biology of the cell 2008;19(6):2544-52.
2008: Alberto López-Bueno; Jose C Segovia; Juan A. Bueren; M Gerard O'Sullivan; Feng Wang; Peter Tattersall; José M Almendral
Evolution to pathogenicity of the parvovirus minute virus of mice in immunodeficient mice involves genetic heterogeneity at the capsid domain that determines tropism.
Journal of virology 2008;82(3):1195-203.
2007: Bärbel Kaufmann; Alberto López-Bueno; Mauricio G Mateu; Paul R Chipman; Christian D S Nelson; Colin R Parrish; José M Almendral; Michael G Rossmann
Minute virus of mice, a parvovirus, in complex with the Fab fragment of a neutralizing monoclonal antibody.
Journal of virology 2007;81(18):9851-8.
2006: Laura Riolobos; Juan Reguera; Mauricio G Mateu; José M Almendral
Nuclear transport of trimeric assembly intermediates exerts a morphogenetic control on the icosahedral parvovirus capsid.
Journal of molecular biology 2006;357(3):1026-38.
2006: Alberto López-Bueno; Mari-Paz Rubio; Nathan Bryant; Robert McKenna; Mavis Agbandje-McKenna; José M Almendral
Host-selected amino acid changes at the sialic acid binding pocket of the parvovirus capsid modulate cell binding affinity and determine virulence.
Journal of virology 2006;80(3):1563-73.
2006: Alberto López-Bueno; L P Villarreal; José M Almendral
Parvovirus variation for disease: a difference with RNA viruses?
Current topics in microbiology and immunology 2006;299():349-70.
2006: Bernhard Mani; Claudia Baltzer; Noelia Valle; José M Almendral; christoph kempf; Carlos Ros
Low pH-dependent endosomal processing of the incoming parvovirus minute virus of mice virion leads to externalization of the VP1 N-terminal sequence (N-VP1), N-VP2 cleavage, and uncoating of the full-length genome.
Journal of virology 2006;80(2):1015-24.
2005: Mari-Paz Rubio; Alberto López-Bueno; José M Almendral
Virulent variants emerging in mice infected with the apathogenic prototype strain of the parvovirus minute virus of mice exhibit a capsid with low avidity for a primary receptor.
Journal of virology 2005;79(17):11280-90.
2005: Maria Kontou; Lakshmanan Govindasamy; Hyun-Joo Nam; Nathan Bryant; Antonio Luis Llamas-Saiz; Concepción Foces-Foces; Eva Hernando; Mari-Paz Rubio; Robert McKenna; José M Almendral; Mavis Agbandje-McKenna
Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice.
Journal of virology 2005;79(17):10931-43.
2005: Juan Reguera; Esther Grueso; Aura Carreira; Cristina Sánchez-Martínez; José M Almendral; Mauricio G Mateu
Functional relevance of amino acid residues involved in interactions with ordered nucleic acid in a spherical virus.
The Journal of biological chemistry 2005;280(18):17969-77.
2004: Beatriz Maroto; Noelia Valle; Rainer Saffrich; José M Almendral
Nuclear export of the nonenveloped parvovirus virion is directed by an unordered protein signal exposed on the capsid surface.
Journal of virology 2004;78(19):10685-94.
2004: Alberto López-Bueno; Noelia Valle; Jesús M Gallego; Joel Pérez; José M Almendral
Enhanced cytoplasmic sequestration of the nuclear export receptor CRM1 by NS2 mutations developed in the host regulates parvovirus fitness.
Journal of virology 2004;78(19):10674-84.
2004: Juan Reguera; Aura Carreira; Laura Riolobos; José M Almendral; Mauricio G Mateu
Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):2724-9.
2004: Aura Carreira; Margarita Menéndez; Juan Reguera; José M Almendral; Mauricio G Mateu
In vitro disassembly of a parvovirus capsid and effect on capsid stability of heterologous peptide insertions in surface loops.
The Journal of biological chemistry 2004;279(8):6517-25.
2003: Jose C Segovia; Guillermo Guenechea; Jesús M Gallego; José M Almendral; Juan A. Bueren
Parvovirus infection suppresses long-term repopulating hematopoietic stem cells.
Journal of virology 2003;77(15):8495-503.
2003: Alberto López-Bueno; Mauricio G Mateu; José M Almendral
High mutant frequency in populations of a DNA virus allows evasion from antibody therapy in an immunodeficient host.
Journal of virology 2003;77(4):2701-8.
2002: Eleuterio Lombardo; Juan Ramirez; Javier Garcia; José M Almendral
Complementary roles of multiple nuclear targeting signals in the capsid proteins of the parvovirus minute virus of mice during assembly and onset of infection.
Journal of virology 2002;76(14):7049-59.
2001: Mari-Paz Rubio; S Guerra; José M Almendral
Genome replication and postencapsidation functions mapping to the nonstructural gene restrict the host range of a murine parvovirus in human cells.
Journal of virology 2001;75(23):11573-82.
2000: B Maroto; Juan Ramirez; José M Almendral
Phosphorylation status of the parvovirus minute virus of mice particle: mapping and biological relevance of the major phosphorylation sites.
Journal of virology 2000;74(23):10892-902.
2000: Eleuterio Lombardo; Juan Ramirez; Mavis Agbandje-McKenna; José M Almendral
A beta-stranded motif drives capsid protein oligomers of the parvovirus minute virus of mice into the nucleus for viral assembly.
Journal of virology 2000;74(8):3804-14.
2000: Eva Hernando; Antonio Luis Llamas-Saiz; Concepción Foces-Foces; Robert McKenna; I Portman; Mavis Agbandje-McKenna; José M Almendral
Biochemical and physical characterization of parvovirus minute virus of mice virus-like particles.
Virology 2000;267(2):299-309.
1999: Jose C Segovia; Jesús M Gallego; Juan A. Bueren; José M Almendral
Severe leukopenia and dysregulated erythropoiesis in SCID mice persistently infected with the parvovirus minute virus of mice.
Journal of virology 1999;73(3):1774-84.