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Mei-Zhen Cui

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TOP 3
Ting Li; Mei-Zhen Cui; Xueqi Fu; Wei Gao; Linlin Zeng; Xuemin Xu
PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.
Jing Shi; Mei-Zhen Cui; Yunzhou Dong; Xuemin Xu
Lysophosphatidic acid induces increased BACE1 expression and Aβ formation.
Feng Hao; Daniel Dongwei Wu; Xuemin Xu; Mei-Zhen Cui
Histamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells.

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All Publications

2013: Ting Li; Mei-Zhen Cui; Xueqi Fu; Wei Gao; Linlin Zeng; Xuemin Xu
PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.
Biochimica et biophysica acta 2013;1832(3):453-74.
2013: Jing Shi; Mei-Zhen Cui; Yunzhou Dong; Xuemin Xu
Lysophosphatidic acid induces increased BACE1 expression and Aβ formation.
Biochimica et biophysica acta 2013;1832(1):29-38.
2012: Feng Hao; Daniel Dongwei Wu; Xuemin Xu; Mei-Zhen Cui
Histamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 2012;303(11):H1344-52.
2012: Guozhang Mao; Mei-Zhen Cui; Yipeng Jin; Tong Li; Xuemin Xu
Pen-2 is dispensable for endoproteolysis of presenilin 1, and nicastrin-Aph subcomplex is important for both γ-secretase assembly and substrate recruitment.
Journal of neurochemistry 2012;123(5):837-44.
2012: Linlin Zeng; Mei-Zhen Cui; Xueqi Fu; Ting Li; Jennifer Liu; Guozhang Mao; Derek C Xu; Xuemin Xu
Death receptor 6 induces apoptosis not through type I or type II pathways, but via a unique mitochondria-dependent pathway by interacting with Bax protein.
The Journal of biological chemistry 2012;287(34):29125-33.
2012: Takuya Iyoda; Carsten Schmitz-Peiffer; Longsheng Sun; Xuemin Xu; Fuqiang Zhang; Feng Hao; Mei-Zhen Cui
Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cδ-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells.
The Journal of biological chemistry 2012;287(27):22635-42.
2010: Feng Hao; Mingqi Tan; Daniel D Wu; Xuemin Xu; Mei-Zhen Cui
LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway.
American journal of physiology. Heart and circulatory physiology 2010;298(3):H974-83.
2009: Jianxin Tan; Guozhang Mao; Mei-Zhen Cui; Bruce Lamb; Man-Sun Sy; Xuemin Xu
Residues at P2-P1 positions of epsilon- and zeta-cleavage sites are important in formation of beta-amyloid peptide.
Neurobiology of disease 2009;36(3):453-60.
2009: Mingqi Tan; Feng Hao; xuemin xu; Guy M Chisolm; Mei-Zhen Cui
Lysophosphatidylcholine activates a novel PKD2-mediated signaling pathway that controls monocyte migration.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(9):1376-82.
2009: Guozhang Mao; Jianxin Tan; Mei-Zhen Cui; Dehua Chui; Xuemin Xu
The GxxxG motif in the transmembrane domain of AbetaPP plays an essential role in the interaction of CTF beta with the gamma-secretase complex and the formation of amyloid-beta.
Journal of Alzheimer's disease : JAD 2009;18(1):167-76.
2008: Jianxin Tan; Guozhang Mao; Mei-Zhen Cui; Shin-Chung Kang; Bruce Lamb; Boon-Seng Wong; Man-Sun Sy; xuemin xu
Effects of gamma-secretase cleavage-region mutations on APP processing and Abeta formation: interpretation with sequential cleavage and alpha-helical model.
Journal of neurochemistry 2008;107(3):722-33.
2008: Feng Hao; Mingqi Tan; xuemin xu; Mei-Zhen Cui
Histamine induces Egr-1 expression in human aortic endothelial cells via the H1 receptor-mediated protein kinase Cdelta-dependent ERK activation pathway.
The Journal of biological chemistry 2008;283(40):26928-36.
2008: Guozhang Mao; Jianxin Tan; Wei Gao; Yongchang Shi; Mei-Zhen Cui; xuemin xu
Both the N-terminal fragment and the protein-protein interaction domain (PDZ domain) are required for the pro-apoptotic activity of presenilin-associated protein PSAP.
Biochimica et biophysica acta 2008;1780(4):696-708.
2007: Feng Hao; Mingqi Tan; xuemin xu; Jiahuai Han; Duane D Miller; Gabor Tigyi; Mei-Zhen Cui
Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha.
Biochimica et biophysica acta 2007;1771(7):883-92.
2007: Guojun Zhao; Jianxin Tan; Guozhang Mao; Mei-Zhen Cui; xuemin xu
The same gamma-secretase accounts for the multiple intramembrane cleavages of APP.
Journal of neurochemistry 2007;100(5):1234-46.
2006: Mei-Zhen Cui; Essam Laag; Longsheng Sun; Mingqi Tan; Guojun Zhao; xuemin xu
Lysophosphatidic acid induces early growth response gene 1 expression in vascular smooth muscle cells: CRE and SRE mediate the transcription.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(5):1029-35.
2006: Yunzhou Dong; Jianxin Tan; Mei-Zhen Cui; Guojun Zhao; Guozhang Mao; Neena Singh; xuemin xu
Calpain inhibitor MDL28170 modulates Abeta formation by inhibiting the formation of intermediate Abeta46 and protecting Abeta from degradation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(2):331-3.
2005: Guojun Zhao; Mei-Zhen Cui; Guozhang Mao; Yunzhou Dong; Jianxin Tan; Longsheng Sun; xuemin xu
gamma-Cleavage is dependent on zeta-cleavage during the proteolytic processing of amyloid precursor protein within its transmembrane domain.
The Journal of biological chemistry 2005;280(45):37689-97.
2004: Guojun Zhao; Guozhang Mao; Jianxin Tan; Yunzhou Dong; Mei-Zhen Cui; Seong-Hun Kim; xuemin xu
Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.
The Journal of biological chemistry 2004;279(49):50647-50.
2004: Mingqi Tan; xuemin xu; Motoi Ohba; Mei-Zhen Cui
Angiotensin II-induced protein kinase D activation is regulated by protein kinase Cdelta and mediated via the angiotensin II type 1 receptor in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2271-6.
2003: Mei-Zhen Cui; Guojun Zhao; Allison L Winokur; Essam Laag; Jason R Bydash; Marc S Penn; Guy M Chisolm; xuemin xu
Lysophosphatidic acid induction of tissue factor expression in aortic smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(2):224-30.
2003: Mingqi Tan; xuemin xu; Motoi Ohba; Wataru Ogawa; Mei-Zhen Cui
Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation.
The Journal of biological chemistry 2003;278(5):2824-8.
2002: xuemin xu; Yong-chang Shi; Wei Gao; Guozhang Mao; Guojun Zhao; Sudesh Agrawal; Guy M Chisolm; Dexin Sui; Mei-Zhen Cui
The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein.
The Journal of biological chemistry 2002;277(50):48913-22.
2000: Marc S Penn; Mei-Zhen Cui; A L Winokur; John R Bethea; Thomas Hamilton; Paul E DiCorleto; Guy M Chisolm
Smooth muscle cell surface tissue factor pathway activation by oxidized low-density lipoprotein requires cellular lipid peroxidation.
Blood 2000;96(9):3056-63.
1999: Mei-Zhen Cui; Marc S Penn; Guy M Chisolm
Native and oxidized low density lipoprotein induction of tissue factor gene expression in smooth muscle cells is mediated by both Egr-1 and Sp1.
The Journal of biological chemistry 1999;274(46):32795-802.
1999: xuemin xu; Y c Shi; X Wu; Pierluigi Gambetti; D Sui; Mei-Zhen Cui
Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1.
The Journal of biological chemistry 1999;274(46):32543-6.
1999: Marc S Penn; C V Patel; Mei-Zhen Cui; Paul E DiCorleto; Guy M Chisolm
LDL increases inactive tissue factor on vascular smooth muscle cell surfaces: hydrogen peroxide activates latent cell surface tissue factor.
Circulation 1999;99(13):1753-9.