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Steven Almo

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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X-Ray Crystallography

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Amino Acid Sequence

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Publications

TOP 3
Alvarado John Jeff; Nemkal Anjana; Sauder J Michael; Russell Marijane; Akiyoshi Donna E; Shi Wuxian; Almo Steven C; Weiss Louis M
Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.
Ho Meng-Chiao; Cassera María B; Madrid Dennis C; Ting Li-Min; Tyler Peter C; Kim Kami; Almo Steven C; Schramm Vern L
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.
Nguyen Tinh T; Fedorov Alexander A; Williams Lakenya; Fedorov Elena V; Li Yingchun; Xu Chengfu; Almo Steven C; Raushel Frank M
The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.

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All Publications

2009: Alvarado John Jeff; Nemkal Anjana; Sauder J Michael; Russell Marijane; Akiyoshi Donna E; Shi Wuxian; Almo Steven C; Weiss Louis M
Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.
Molecular and biochemical parasitology 2009;168(2):158-67.
2009: Ho Meng-Chiao; Cassera María B; Madrid Dennis C; Ting Li-Min; Tyler Peter C; Kim Kami; Almo Steven C; Schramm Vern L
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.
Biochemistry 2009;48(40):9618-26.
2009: Nguyen Tinh T; Fedorov Alexander A; Williams Lakenya; Fedorov Elena V; Li Yingchun; Xu Chengfu; Almo Steven C; Raushel Frank M
The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.
Biochemistry 2009;48(37):8879-90.
2009: Burgos Emmanuel S; Ho Meng-Chiao; Almo Steven C; Schramm Vern L
A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):13748-53.
2009: Zhan Chenyang; Yan Qingrong; Patskovsky Yury; Li Zhenhong; Toro Rafael; Meyer Amanda; Cheng Huiyong; Brenowitz Michael; Nathenson Stanley G; Almo Steven C
Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry 2009;48(32):7636-45.
2009: Cummings Jennifer A; Fedorov Alexander A; Xu Chengfu; Brown Shoshana; Fedorov Elena; Babbitt Patricia C; Almo Steven C; Raushel Frank M
Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.
Biochemistry 2009;48(27):6469-81.
2009: Zencheck Wendy D; Xiao Hui; Nolen Brad J; Angeletti Ruth Hogue; Pollard Thomas D; Almo Steven C
Nucleotide- and activator-dependent structural and dynamic changes of arp2/3 complex monitored by hydrogen/deuterium exchange and mass spectrometry.
Journal of molecular biology 2009;390(3):414-27.
2009: Chan Kui K; Wood B McKay; Fedorov Alexander A; Fedorov Elena V; Imker Heidi J; Amyes Tina L; Richard John P; Almo Steven C; Gerlt John A
Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization.
Biochemistry 2009;48(24):5518-31.
2009: Drumm Joshua E; Mi Kaixia; Bilder Patrick; Sun Meihao; Lim Jihyeon; Bielefeldt-Ohmann Helle; Basaraba Randall; So Melvin; Zhu Guofeng; Tufariello Joann M; Izzo Angelo A; Orme Ian M; Almo Steve C; Leyh Thomas S; Chan John
Mycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infection.
PLoS pathogens 2009;5(5):e1000460.
2009: Chattopadhyay Kausik; Lazar-Molnar Eszter; Yan Qingrong; Rubinstein Rotem; Zhan Chenyang; Vigdorovich Vladimir; Ramagopal Udupi A; Bonanno Jeffrey; Nathenson Stanley G; Almo Steven C
Sequence, structure, function, immunity: structural genomics of costimulation.
Immunological reviews 2009;229(1):356-86.
2009: Chattopadhyay Kausik; Ramagopal Udupi A; Nathenson Stanley G; Almo Steven C
1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 5):434-9.
2009: Xiang Dao Feng; Patskovsky Yury; Xu Chengfu; Meyer Amanda J; Sauder J Michael; Burley Stephen K; Almo Steven C; Raushel Frank M
Functional identification of incorrectly annotated prolidases from the amidohydrolase superfamily of enzymes.
Biochemistry 2009;48(17):3730-42.
2009: Gutierrez Jemy A; Crowder Tamara; Rinaldo-Matthis Agnes; Ho Meng-Chiao; Almo Steven C; Schramm Vern L
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
Nature chemical biology 2009;5(4):251-7.
2009: Ball T; Linhart B; Sonneck K; Blatt K; Herrmann H; Valent P; Stoecklinger A; Lupinek C; Thalhamer J; Fedorov A A; Almo S C; Valenta R
Reducing allergenicity by altering allergen fold: a mosaic protein of Phl p 1 for allergy vaccination.
Allergy 2009;64(4):569-80.
2009: Pieper Ursula; Chiang Ranyee; Seffernick Jennifer J; Brown Shoshana D; Glasner Margaret E; Kelly Libusha; Eswar Narayanan; Sauder J Michael; Bonanno Jeffrey B; Swaminathan Subramanyam; Burley Stephen K; Zheng Xiaojing; Chance Mark R; Almo Steven C; Gerlt John A; Raushel Frank M; Jacobson Matthew P; Babbitt Patricia C; Sali Andrej
Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies.
Journal of structural and functional genomics 2009;10(2):107-25.
2009: Sakai Ayano; Fedorov Alexander A; Fedorov Elena V; Schnoes Alexandra M; Glasner Margaret E; Brown Shoshana; Rutter Marc E; Bain Kevin; Chang Shawn; Gheyi Tarun; Sauder J Michael; Burley Stephen K; Babbitt Patricia C; Almo Steven C; Gerlt John A
Evolution of Enzymatic Activities in the Enolase Superfamily: Stereochemically Distinct Mechanisms in Two Families of cis,cis-Muconate Lactonizing Enzymes.
Biochemistry 2009;48(11):2569-70.
2009: Leiman Petr G; Basler Marek; Ramagopal Udupi A; Bonanno Jeffrey B; Sauder J Michael; Pukatzki Stefan; Burley Stephen K; Almo Steven C; Mekalanos John J
Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4154-9.
2009: Xiang Dao Feng; Kolb Peter; Fedorov Alexander A; Meier Monika M; Fedorov Lena V; Nguyen T Tinh; Sterner Reinhard; Almo Steven C; Shoichet Brian K; Raushel Frank M
Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.
Biochemistry 2009;48(10):2237-47.
2009: Sakai Ayano; Fedorov Alexander A; Fedorov Elena V; Schnoes Alexandra M; Glasner Margaret E; Brown Shoshana; Rutter Marc E; Bain Kevin; Chang Shawn; Gheyi Tarun; Sauder J Michael; Burley Stephen K; Babbitt Patricia C; Almo Steven C; Gerlt John A
Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes.
Biochemistry 2009;48(7):1445-53.
2008: Kalyanaraman Chakrapani; Imker Heidi J; Fedorov Alexander A; Fedorov Elena V; Glasner Margaret E; Babbitt Patricia C; Almo Steven C; Gerlt John A; Jacobson Matthew P
Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening.
Structure (London, England : 1993) 2008;16(11):1668-77.
2008: Rakus John F; Fedorov Alexander A; Fedorov Elena V; Glasner Margaret E; Hubbard Brian K; Delli Joseph D; Babbitt Patricia C; Almo Steven C; Gerlt John A
Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase.
Biochemistry 2008;47(38):9944-54.
2008: Hudkins Robert L; Diebold James L; Tao Ming; Josef Kurt A; Park Chung Ho; Angeles Thelma S; Aimone Lisa D; Husten Jean; Ator Mark A; Meyer Sheryl L; Holskin Beverly P; Durkin John T; Fedorov Alexander A; Fedorov Elena V; Almo Steven C; Mathiasen Joanne R; Bozyczko-Coyne Donna; Saporito Michael S; Scott Richard W; Mallamo John P
Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models.
Journal of medicinal chemistry 2008;51(18):5680-9.
2008: Kim Jungwook; Tsai Ping-Chuan; Chen Shi-Lu; Himo Fahmi; Almo Steven C; Raushel Frank M
Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase.
Biochemistry 2008;47(36):9497-504.
2008: Chan Kui K; Fedorov Alexander A; Fedorov Elena V; Almo Steven C; Gerlt John A
Structural basis for substrate specificity in phosphate binding (beta/alpha)8-barrels: D-allulose 6-phosphate 3-epimerase from Escherichia coli K-12.
Biochemistry 2008;47(36):9608-17.
2008: Lázár-Molnár Eszter; Yan Qingrong; Cao Erhu; Ramagopal Udupi; Nathenson Stanley G; Almo Steven C
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(30):10483-8.
2008: Malashkevich Vladimir N; Varney Kristen M; Garrett Sarah C; Wilder Paul T; Knight David; Charpentier Thomas H; Ramagopal Udupi A; Almo Steven C; Weber David J; Bresnick Anne R
Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA.
Biochemistry 2008;47(18):5111-26.
2008: Lázár-Molnár Eszter; Gácser Attila; Freeman Gordon J; Almo Steven C; Nathenson Stanley G; Nosanchuk Joshua D
The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2658-63.
2008: Gräslund Susanne; Nordlund Pär; Weigelt Johan; Hallberg B Martin; Bray James; Gileadi Opher; Knapp Stefan; Oppermann Udo; Arrowsmith Cheryl; Hui Raymond; Ming Jinrong; dhe-Paganon Sirano; Park Hee-won; Savchenko Alexei; Yee Adelinda; Edwards Aled; Vincentelli Renaud; Cambillau Christian; Kim Rosalind; Kim Sung-Hou; Rao Zihe; Shi Yunyu; Terwilliger Thomas C; Kim Chang-Yub; Hung Li-Wei; Waldo Geoffrey S; Peleg Yoav; Albeck Shira; Unger Tamar; Dym Orly; Prilusky Jaime; Sussman Joel L; Stevens Ray C; Lesley Scott A; Wilson Ian A; Joachimiak Andrzej; Collart Frank; Dementieva Irina; Donnelly Mark I; Eschenfeldt William H; Kim Youngchang; Stols Lucy; Wu Ruying; Zhou Min; Burley Stephen K; Emtage J Spencer; Sauder J Michael; Thompson Devon; Bain Kevin; Luz John; Gheyi Tarun; Zhang Fred; Atwell Shane; Almo Steven C; Bonanno Jeffrey B; Fiser Andras; Swaminathan Sivasubramanian; Studier F William; Chance Mark R; Sali Andrej; Acton Thomas B; Xiao Rong; Zhao Li; Ma Li Chung; Hunt John F; Tong Liang; Cunningham Kellie; Inouye Masayori; Anderson Stephen; Janjua Heleema; Shastry Ritu; Ho Chi Kent; Wang Dongyan; Wang Huang; Jiang Mei; Montelione Gaetano T; Stuart David I; Owens Raymond J; Daenke Susan; Schütz Anja; Heinemann Udo; Yokoyama Shigeyuki; Büssow Konrad; Gunsalus Kristin C
Protein production and purification.
Nature methods 2008;5(2):135-46.
2008: Chattopadhyay Kausik; Ramagopal Udupi A; Brenowitz Michael; Nathenson Stanley G; Almo Steven C
Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):635-40.
2008: Nguyen Tinh T; Brown Shoshana; Fedorov Alexander A; Fedorov Elena V; Babbitt Patricia C; Almo Steven C; Raushel Frank M
At the periphery of the amidohydrolase superfamily: Bh0493 from Bacillus halodurans catalyzes the isomerization of D-galacturonate to D-tagaturonate.
Biochemistry 2008;47(4):1194-206.
2008: Rinaldo-Matthis Agnes; Murkin Andrew S; Ramagopal Udupi A; Clinch Keith; Mee Simon P H; Evans Gary B; Tyler Peter C; Furneaux Richard H; Almo Steven C; Schramm Vern L
L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
Journal of the American Chemical Society 2008;130(3):842-4.
2008: Chao Jeffrey A; Patskovsky Yury; Almo Steven C; Singer Robert H
Structural basis for the coevolution of a viral RNA-protein complex.
Nature structural & molecular biology 2008;15(1):103-5.
2007: Chattopadhyay Kausik; Ramagopal Udupi A; Mukhopadhaya Arunika; Malashkevich Vladimir N; Dilorenzo Teresa P; Brenowitz Michael; Nathenson Stanley G; Almo Steven C
Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19452-7.
2007: Rakus John F; Fedorov Alexander A; Fedorov Elena V; Glasner Margaret E; Vick Jacob E; Babbitt Patricia C; Almo Steven C; Gerlt John A
Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Biochemistry 2007;46(45):12896-908.
2007: Taylor Erika A; Rinaldo-Matthis Agnes; Li Lei; Ghanem Mahmoud; Hazleton Keith Z; Cassera María B; Almo Steven C; Schramm Vern L
Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
Biochemistry 2007;46(43):12405-15.
2007: Almo Steven C; Bonanno Jeffrey B; Sauder J Michael; Emtage Spencer; Dilorenzo Teresa P; Malashkevich Vladimir; Wasserman Steven R; Swaminathan S; Eswaramoorthy Subramaniam; Agarwal Rakhi; Kumaran Desigan; Madegowda Mahendra; Ragumani Sugadev; Patskovsky Yury; Alvarado Johnjeff; Ramagopal Udupi A; Faber-Barata Joana; Chance Mark R; Sali Andrej; Fiser Andras; Zhang Zhong-yin; Lawrence David S; Burley Stephen K
Structural genomics of protein phosphatases.
Journal of structural and functional genomics 2007;8(2-3):121-40.
2007: Yew Wen Shan; Fedorov Alexander A; Fedorov Elena V; Almo Steven C; Gerlt John A
Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Biochemistry 2007;46(33):9564-77.
2007: Vrtala Susanne; Focke Margarete; Kopec Jolanta; Verdino Petra; Hartl Arnulf; Sperr Wolfgang R; Fedorov Alexander A; Ball Tanja; Almo Steve; Valent Peter; Thalhamer Josef; Keller Walter; Valenta Rudolf
Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1730-9.
2007: Song Ling; Kalyanaraman Chakrapani; Fedorov Alexander A; Fedorov Elena V; Glasner Margaret E; Brown Shoshana; Imker Heidi J; Babbitt Patricia C; Almo Steven C; Jacobson Matthew P; Gerlt John A
Prediction and assignment of function for a divergent N-succinyl amino acid racemase.
Nature chemical biology 2007;3(8):486-91.
2007: Hermann Johannes C; Marti-Arbona Ricardo; Fedorov Alexander A; Fedorov Elena; Almo Steven C; Shoichet Brian K; Raushel Frank M
Structure-based activity prediction for an enzyme of unknown function.
Nature 2007;448(7155):775-9.
2007: Hall Richard S; Brown Shoshana; Fedorov Alexander A; Fedorov Elena V; Xu Chengfu; Babbitt Patricia C; Almo Steven C; Raushel Frank M
Structural diversity within the mononuclear and binuclear active sites of N-acetyl-D-glucosamine-6-phosphate deacetylase.
Biochemistry 2007;46(27):7953-62.
2007: Yan Qingrong; Malashkevich Vladimir N; Fedorov Alexander; Fedorov Elena; Cao Erhu; Lary Jeffrey W; Cole James L; Nathenson Stanley G; Almo Steven C
Structure of CD84 provides insight into SLAM family function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10583-8.
2007: McLachlan Glendon D; Cahill Sean M; Girvin Mark E; Almo Steven C
Acid-induced equilibrium folding intermediate of human platelet profilin.
Biochemistry 2007;46(23):6931-43.
2007: Murkin Andrew S; Birck Matthew R; Rinaldo-Matthis Agnes; Shi Wuxian; Taylor Erika A; Almo Steven C; Schramm Vern L
Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry 2007;46(17):5038-49.
2007: Velge P; Herler M; Johansson J; Roche S M; Témoin S; Fedorov A A; Gracieux P; Almo S C; Goebel W; Cossart P
A naturally occurring mutation K220T in the pleiotropic activator PrfA of Listeria monocytogenes results in a loss of virulence due to decreasing DNA-binding affinity.
Microbiology (Reading, England) 2007;153(Pt 4):995-1005.
2007: Imker Heidi J; Fedorov Alexander A; Fedorov Elena V; Almo Steven C; Gerlt John A
Mechanistic diversity in the RuBisCO superfamily: the "enolase" in the methionine salvage pathway in Geobacillus kaustophilus.
Biochemistry 2007;46(13):4077-89.
2007: Cao Erhu; Zang Xingxing; Ramagopal Udupi A; Mukhopadhaya Arunika; Fedorov Alexander; Fedorov Elena; Zencheck Wendy D; Lary Jeffrey W; Cole James L; Deng Haiteng; Xiao Hui; Dilorenzo Teresa P; Allison James P; Nathenson Stanley G; Almo Steven C
T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface.
Immunity 2007;26(3):311-21.
2007: Kiselar Janna G; Mahaffy Rachel; Pollard Thomas D; Almo Steven C; Chance Mark R
Visualizing Arp2/3 complex activation mediated by binding of ATP and WASp using structural mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(5):1552-7.
2007: Rinaldo-Matthis Agnes; Wing Corin; Ghanem Mahmoud; Deng Hua; Wu Peng; Gupta Arti; Tyler Peter C; Evans Gary B; Furneaux Richard H; Almo Steven C; Wang Ching C; Schramm Vern L
Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Biochemistry 2007;46(3):659-68.
2007: Benchaar Sabrina A; Xie Yongming; Phillips Martin; Loo Rachel R Ogorzalek; Galkin Vitold E; Orlova Albina; Thevis Mario; Muhlrad Andras; Almo Steven C; Loo Joseph A; Egelman Edward H; Reisler Emil
Mapping the interaction of cofilin with subdomain 2 on actin.
Biochemistry 2007;46(1):225-33.
2006: Lazar-Molnar Eszter; Almo Steven C; Nathenson Stanley G
The interchain disulfide linkage is not a prerequisite but enhances CD28 costimulatory function.
Cellular immunology 2006;244(2):125-9.
2006: Yew Wen Shan; Fedorov Alexander A; Fedorov Elena V; Wood Bryant McKay; Almo Steven C; Gerlt John A
Evolution of enzymatic activities in the enolase superfamily: D-tartrate dehydratase from Bradyrhizobium japonicum.
Biochemistry 2006;45(49):14598-608.
2006: Yew Wen Shan; Fedorov Alexander A; Fedorov Elena V; Rakus John F; Pierce Richard W; Almo Steven C; Gerlt John A
Evolution of enzymatic activities in the enolase superfamily: L-fuconate dehydratase from Xanthomonas campestris.
Biochemistry 2006;45(49):14582-97.
2006: Singh Vipender; Shi Wuxian; Almo Steven C; Evans Gary B; Furneaux Richard H; Tyler Peter C; Painter Gavin F; Lenz Dirk H; Mee Simon; Zheng Renjian; Schramm Vern L
Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Biochemistry 2006;45(43):12929-41.
2006: Cao Erhu; Ramagopal Udupi A; Fedorov Alexander; Fedorov Elena; Yan Qingrong; Lary Jeffrey W; Cole James L; Nathenson Stanley G; Almo Steven C
NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family.
Immunity 2006;25(4):559-70.
2006: Zhang Y; Vorobiev Sergey M; Gibson Bruce G; Hao Binghua; Sidhu Gurjit S; Mishra Vishnu S; Yarmola Elena G; Bubb Michael R; Almo Steven C; Southwick Frederick S
A CapG gain-of-function mutant reveals critical structural and functional determinants for actin filament severing.
The EMBO journal 2006;25(19):4458-67.
2006: Chattopadhyay Kausik; Bhatia Sumeena; Fiser Andras; Almo Steven C; Nathenson Stanley G
Structural basis of inducible costimulator ligand costimulatory function: determination of the cell surface oligomeric state and functional mapping of the receptor binding site of the protein.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3920-9.
2006: Flicker Sabine; Steinberger Peter; Ball Tanja; Krauth Maria-Theresa; Verdino Petra; Valent Peter; Almo Steve; Valenta Rudolf
Spatial clustering of the IgE epitopes on the major timothy grass pollen allergen Phl p 1: importance for allergenic activity.
The Journal of allergy and clinical immunology 2006;117(6):1336-43.
2006: Kim Jungwook; Malashkevich Vladimir; Roday Setu; Lisbin Michael; Schramm Vern L; Almo Steven C
Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.
Biochemistry 2006;45(20):6407-16.
2006: Bhatia Sumeena; Edidin Michael; Almo Steven C; Nathenson Stanley G
B7-1 and B7-2: similar costimulatory ligands with different biochemical, oligomeric and signaling properties.
Immunology letters 2006;104(1-2):70-5.
2006: Patskovsky Yury; Patskovska Larysa; Almo Steven C; Listowsky Irving
Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry 2006;45(12):3852-62.
2006: Chiu Wah; Baker Matthew L; Almo Steven C
Structural biology of cellular machines.
Trends in cell biology 2006;16(3):144-50.
2006: Roden Matthew M; Brims Daniel R; Fedorov Alexander A; DiLorenzo Teresa P; Almo Steven C; Nathenson Stanley G
Structural analysis of H2-Db class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: implications for the mechanism underlying variations in antigen presentation.
Molecular immunology 2006;43(9):1370-8.
2006: Akana Julie; Fedorov Alexander A; Fedorov Elena; Novak Walter R P; Babbitt Patricia C; Almo Steven C; Gerlt John A
D-Ribulose 5-phosphate 3-epimerase: functional and structural relationships to members of the ribulose-phosphate binding (beta/alpha)8-barrel superfamily.
Biochemistry 2006;45(8):2493-503.
2005: Zhan Chenyang; Fedorov Elena V; Shi Wuxian; Ramagopal U A; Thirumuruhan R; Manjasetty Babu A; Almo Steve C; Fiser Andras; Chance Mark R; Fedorov Alexander A
The ybeY protein from Escherichia coli is a metalloprotein.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 11):959-63.
2005: Bhatia Sumeena; Edidin Michael; Almo Steven C; Nathenson Stanley G
Different cell surface oligomeric states of B7-1 and B7-2: implications for signaling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15569-74.
2005: Parsa Tania; Cunningham Sandra J; Wall Stephen P; Almo Steven C; Crain Ellen F
The usefulness of urine fluorescence for suspected antifreeze ingestion in children.
The American journal of emergency medicine 2005;23(6):787-92.
2005: Sun Jin-Peng; Wang Wei-Qing; Yang Heyi; Liu Sijiu; Liang Fubo; Fedorov Alexander A; Almo Steven C; Zhang Zhong-Yin
Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion.
Biochemistry 2005;44(36):12009-21.
2005: Ramagopal Udupi A; Dauter Zbigniew; Thirumuruhan Radhakannan; Fedorov Elena; Almo Steven C
Radiation-induced site-specific damage of mercury derivatives: phasing and implications.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 9):1289-98.
2005: Tseng Yiider; Kole Thomas P; Lee Jerry S H; Fedorov Elena; Almo Steven C; Schafer Benjamin W; Wirtz Denis
How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response.
Biochemical and biophysical research communications 2005;334(1):183-92.
2005: Quintero-Monzon Omar; Rodal Avital A; Strokopytov Boris; Almo Steven C; Goode Bruce L
Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions.
Molecular biology of the cell 2005;16(7):3128-39.
2005: Dulyaninova Natalya G; Malashkevich Vladimir N; Almo Steven C; Bresnick Anne R
Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation.
Biochemistry 2005;44(18):6867-76.
2005: Patskovska Larysa N; Patskovsky Yury V; Almo Steven C; Hirsch Rhoda Elison
COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 5):566-73.
2005: Guan Jing-Qu; Takamoto Keiji; Almo Steven C; Reisler Emil; Chance Mark R
Structure and dynamics of the actin filament.
Biochemistry 2005;44(9):3166-75.
2005: Strokopytov Boris V; Fedorov Alexander; Mahoney Nicole M; Kessels Michael; Drubin David G; Almo Steven C
Phased translation function revisited: structure solution of the cofilin-homology domain from yeast actin-binding protein 1 using six-dimensional searches.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 3):285-93.
2005: Ball Tanja; Edstrom William; Mauch Ludwig; Schmitt Jacky; Leistler Bernd; Fiebig Helmut; Sperr Wolfgang R; Hauswirth Alexander W; Valent Peter; Kraft Dietrich; Almo Steven C; Valenta Rudolf
Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1.
The FEBS journal 2005;272(1):217-27.
2005: Bonanno Jeffrey B; Almo Steven C; Bresnick Anne; Chance Mark R; Fiser Andras; Swaminathan S; Jiang J; Studier F William; Shapiro Lawrence; Lima Christopher D; Gaasterland Theresa M; Sali Andrej; Bain Kevin; Feil Ingeborg; Gao Xia; Lorimer Don; Ramos Aurora; Sauder J Michael; Wasserman Steven R; Emtage Spencer; D'Amico Kevin L; Burley Stephen K
New York-Structural GenomiX Research Consortium (NYSGXRC): a large scale center for the protein structure initiative.
Journal of structural and functional genomics 2005;6(2-3):225-32.
2004: Mattila Pieta K; Quintero-Monzon Omar; Kugler Jamie; Moseley James B; Almo Steven C; Lappalainen Pekka; Goode Bruce L
A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein.
Molecular biology of the cell 2004;15(11):5158-71.
2004: Muhlrad Andras; Kudryashov Dmitry; Michael Peyser Y; Bobkov Andrey A; Almo Steve C; Reisler Emil
Cofilin induced conformational changes in F-actin expose subdomain 2 to proteolysis.
Journal of molecular biology 2004;342(5):1559-67.
2004: Sukumvanich P; DesMarais V; Sarmiento C V; Wang Y; Ichetovkin I; Mouneimne G; Almo S; Condeelis J
Cellular localization of activated N-WASP using a conformation-sensitive antibody.
Cell motility and the cytoskeleton 2004;59(2):141-52.
2004: Dodatko Tetyana; Fedorov Alexander A; Grynberg Marcin; Patskovsky Yury; Rozwarski Denise A; Jaroszewski Lukasz; Aronoff-Spencer Eliah; Kondraskina Elena; Irving Tom; Godzik Adam; Almo Steven C
Crystal structure of the actin binding domain of the cyclase-associated protein.
Biochemistry 2004;43(33):10628-41.
2004: Mohri Kurato; Vorobiev Sergeui; Fedorov Alexander A; Almo Steven C; Ono Shoichiro
Identification of functional residues on Caenorhabditis elegans actin-interacting protein 1 (UNC-78) for disassembly of actin depolymerizing factor/cofilin-bound actin filaments.
The Journal of biological chemistry 2004;279(30):31697-707.
2004: Klein Michael G; Shi Wuxian; Ramagopal Udupi; Tseng Yiider; Wirtz Denis; Kovar David R; Staiger Christopher J; Almo Steven C
Structure of the actin crosslinking core of fimbrin.
Structure (London, England : 1993) 2004;12(6):999-1013.
2004: Guan Jing-Qu; Almo Steven C; Chance Mark R
Synchrotron radiolysis and mass spectrometry: a new approach to research on the actin cytoskeleton.
Accounts of chemical research 2004;37(4):221-9.
2004: Shi Wuxian; Ting Li-Min; Kicska Gregory A; Lewandowicz Andrzej; Tyler Peter C; Evans Gary B; Furneaux Richard H; Kim Kami; Almo Steve C; Schramm Vern L
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.
The Journal of biological chemistry 2004;279(18):18103-6.
2004: Zhang Xuewu; Schwartz Jean-Claude D; Guo Xiaoling; Bhatia Sumeena; Cao Erhu; Lorenz Michael; Cammer Michael; Chen Lieping; Zhang Zhong-Yin; Edidin Michael A; Nathenson Stanley G; Almo Steven C
Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity 2004;20(3):337-47.
2004: Bobkov Andrey A; Muhlrad Andras; Shvetsov Alexander; Benchaar Sabrina; Scoville Damon; Almo Steven C; Reisler Emil
Cofilin (ADF) affects lateral contacts in F-actin.
Journal of molecular biology 2004;337(1):93-104.
2004: Singh Vipender; Shi Wuxian; Evans Gary B; Tyler Peter C; Furneaux Richard H; Almo Steven C; Schramm Vern L
Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
Biochemistry 2004;43(1):9-18.
2003: Guan Jing-Qu; Almo Steven C; Reisler Emil; Chance Mark R
Structural reorganization of proteins revealed by radiolysis and mass spectrometry: G-actin solution structure is divalent cation dependent.
Biochemistry 2003;42(41):11992-2000.
2003: Kiselar Janna G; Janmey Paul A; Almo Steven C; Chance Mark R
Structural analysis of gelsolin using synchrotron protein footprinting.
Molecular & cellular proteomics : MCP 2003;2(10):1120-32.
2003: Huang Raymond Y; Boulton Simon J; Vidal Marc; Almo Steve C; Bresnick Anne R; Chance Mark R
High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins.
Biochemical and biophysical research communications 2003;307(4):928-34.
2003: Sun Jin-Peng; Wu Li; Fedorov Alexander A; Almo Steven C; Zhang Zhong-Yin
Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor.
The Journal of biological chemistry 2003;278(35):33392-9.
2003: Lewandowicz Andrzej; Shi Wuxian; Evans Gary B; Tyler Peter C; Furneaux Richard H; Basso Luiz A; Santos Diogenes S; Almo Steven C; Schramm Vern L
Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Biochemistry 2003;42(20):6057-66.
2003: Vorobiev S; Strokopytov B; Drubin D G; Frieden C; Ono S; Condeelis J; Rubenstein P A; Almo S C
The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5760-5.
2003: Kiselar Janna G; Janmey Paul A; Almo Steven C; Chance Mark R
Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3942-7.
2003: Sun Jin-Peng; Fedorov Alexander A; Lee Seung-Yub; Guo Xiao-Ling; Shen Kui; Lawrence David S; Almo Steven C; Zhang Zhong-Yin
Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.
The Journal of biological chemistry 2003;278(14):12406-14.
2003: Zhang Xuewu; Schwartz Jean-Claude D; Almo Steven C; Nathenson Stanley G
Crystal structure of the receptor-binding domain of human B7-2: insights into organization and signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2586-91.
2002: Kicska Greg A; Tyler Peter C; Evans Gary B; Furneaux Richard H; Shi Wuxian; Fedorov Alexander; Lewandowicz Andrzej; Cahill Sean M; Almo Steven C; Schramm Vern L
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Biochemistry 2002;41(49):14489-98.
2002: Dewan John C; Feeling-Taylor Angela; Puius Yoram A; Patskovska Larysa; Patskovsky Yury; Nagel Ronald L; Almo Steven C; Hirsch Rhoda Elison
Structure of mutant human carbonmonoxyhemoglobin C (betaE6K) at 2.0 A resolution.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):2038-42.
2002: Bobkov Andrey A; Muhlrad Andras; Kokabi Kaveh; Vorobiev Sergey; Almo Steven C; Reisler Emil
Structural effects of cofilin on longitudinal contacts in F-actin.
Journal of molecular biology 2002;323(4):739-50.
2002: Shi Wuxian; Sarver Anne E; Wang Ching C; Tanaka Kelly S E; Almo Steven C; Schramm Vern L
Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration.
The Journal of biological chemistry 2002;277(42):39981-8.
2002: Tseng Yiider; Schafer Benjamin W; Almo Steven C; Wirtz Denis
Functional synergy of actin filament cross-linking proteins.
The Journal of biological chemistry 2002;277(28):25609-16.
2002: Zhang Xuewu; Schwartz Jean-Claude D; Almo Steven C; Nathenson Stanley G
Expression, refolding, purification, molecular characterization, crystallization, and preliminary X-ray analysis of the receptor binding domain of human B7-2.
Protein expression and purification 2002;25(1):105-13.
2002: Bubb Michael R; Govindasamy Lakshmanan; Yarmola Elena G; Vorobiev Sergey M; Almo Steven C; Somasundaram Thayumanasamy; Chapman Michael S; Agbandje-McKenna Mavis; McKenna Robert
Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
The Journal of biological chemistry 2002;277(23):20999-1006.
2002: Guan Jing-Qu; Vorobiev Sergeui; Almo Steven C; Chance Mark R
Mapping the G-actin binding surface of cofilin using synchrotron protein footprinting.
Biochemistry 2002;41(18):5765-75.
2002: Schwartz Jean-Claude D; Zhang Xuewu; Nathenson Stanley G; Almo Steven C
Structural mechanisms of costimulation.
Nature immunology 2002;3(5):427-34.
2002: Chance Mark R; Bresnick Anne R; Burley Stephen K; Jiang Jian-Sheng; Lima Christopher D; Sali Andrej; Almo Steven C; Bonanno Jeffrey B; Buglino John A; Boulton Simon; Chen Hua; Eswar Narayanan; He Guoshun; Huang Raymond; Ilyin Valentin; McMahan Linda; Pieper Ursula; Ray Soumya; Vidal Marc; Wang Li Kai
Structural genomics: a pipeline for providing structures for the biologist.
Protein science : a publication of the Protein Society 2002;11(4):723-38.
2002: Ostrov David A; Roden Matthew M; Shi Wuxian; Palmieri Edith; Christianson Gregory J; Mendoza Lisa; Villaflor Gilbert; Tilley Darcie; Shastri Nilabh; Grey Howard; Almo Steven C; Roopenian Derry; Nathenson Stanley G
How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):283-9.
2001: Goldsmith S C; Guan J Q; Almo S; Chance M
Synchrotron protein footprinting: a technique to investigate protein-protein interactions.
Journal of biomolecular structure & dynamics 2001;19(3):405-18.
2001: Shi W; Tanaka K S; Crother T R; Taylor M W; Almo S C; Schramm V L
Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
Biochemistry 2001;40(36):10800-9.
2001: Shi W; Basso L A; Santos D S; Tyler P C; Furneaux R H; Blanchard J S; Almo S C; Schramm V L
Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry 2001;40(28):8204-15.
2001: Tseng Y; Fedorov E; McCaffery J M; Almo S C; Wirtz D
Micromechanics and ultrastructure of actin filament networks crosslinked by human fascin: a comparison with alpha-actinin.
Journal of molecular biology 2001;310(2):351-66.
2001: Zhang X; Schwartz J C; Nathenson S G; Almo S C
Crystallization and preliminary X-ray analysis of the complex between human CTLA-4 and B7-2.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 6):898-9.
2001: Rustandi R; Vallely K M; Varlamova O; Klein M G; Almo S C; Bresnick A R; Weber D J
1H, 13C, 15N NMR sequence-specific resonance assignments for human apo-Mts1 (S100A4).
Journal of biomolecular NMR 2001;19(4):381-2.
2001: Schwartz J C; Zhang X; Fedorov A A; Nathenson S G; Almo S C
Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.
Nature 2001;410(6828):604-8.
2001: Fedorov A; Shi W; Kicska G; Fedorov E; Tyler P C; Furneaux R H; Hanson J C; Gainsford G J; Larese J Z; Schramm V L; Almo S C
Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
Biochemistry 2001;40(4):853-60.
2000: Ostrov D A; Shi W; Schwartz J C; Almo S C; Nathenson S G
Structure of murine CTLA-4 and its role in modulating T cell responsiveness.
Science (New York, N.Y.) 2000;290(5492):816-9.
2000: Melián A; Watts G F; Shamshiev A; De Libero G; Clatworthy A; Vincent M; Brenner M B; Behar S; Niazi K; Modlin R L; Almo S; Ostrov D; Nathenson S G; Porcelli S A
Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4494-504.
2000: Wolven A K; Belmont L D; Mahoney N M; Almo S C; Drubin D G
In vivo importance of actin nucleotide exchange catalyzed by profilin.
The Journal of cell biology 2000;150(4):895-904.
2000: Apgar J; Tseng Y; Fedorov E; Herwig M B; Almo S C; Wirtz D
Multiple-particle tracking measurements of heterogeneities in solutions of actin filaments and actin bundles.
Biophysical journal 2000;79(2):1095-106.
2000: Sarmiento M; Puius Y A; Vetter S W; Keng Y F; Wu L; Zhao Y; Lawrence D S; Almo S C; Zhang Z Y
Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry 2000;39(28):8171-9.
2000: Shi W; Munagala N R; Wang C C; Li C M; Tyler P C; Furneaux R H; Grubmeyer C; Schramm V L; Almo S C
Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry 2000;39(23):6781-90.
2000: Puius Y A; Fedorov E V; Eichinger L; Schleicher M; Almo S C
Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry 2000;39(18):5322-31.
2000: Burke E; Mahoney N M; Almo S C; Barik S
Profilin is required for optimal actin-dependent transcription of respiratory syncytial virus genome RNA.
Journal of virology 2000;74(2):669-75.
1999: Burley S K; Almo S C; Bonanno J B; Capel M; Chance M R; Gaasterland T; Lin D; Sali A; Studier F W; Swaminathan S
Structural genomics: beyond the human genome project.
Nature genetics 1999;23(2):151-7.
1999: Levin S; Almo S C; Satir B H
Functional diversity of the phosphoglucomutase superfamily: structural implications.
Protein engineering 1999;12(9):737-46.
1999: Shi W; Li C M; Tyler P C; Furneaux R H; Cahill S M; Girvin M E; Grubmeyer C; Schramm V L; Almo S C
The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
Biochemistry 1999;38(31):9872-80.
1999: Shi W; Schramm V L; Almo S C
Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-å crystal structure.
The Journal of biological chemistry 1999;274(30):21114-20.
1999: Mahoney N M; Rozwarski D A; Fedorov E; Fedorov A A; Almo S C
Profilin binds proline-rich ligands in two distinct amide backbone orientations.
Nature structural biology 1999;6(7):666-71.
1999: Fedorov A A; Fedorov E; Gertler F; Almo S C
Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function.
Nature structural biology 1999;6(7):661-5.
1999: Shi W; Li C M; Tyler P C; Furneaux R H; Grubmeyer C; Schramm V L; Almo S C
The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
Nature structural biology 1999;6(6):588-93.
1998: Liu S; Fedorov A A; Pollard T D; Lattman E E; Almo S C; Magnus K A
Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii.
Journal of structural biology 1998;123(1):22-9.
1998: Hanein D; Volkmann N; Goldsmith S; Michon A M; Lehman W; Craig R; DeRosier D; Almo S; Matsudaira P
An atomic model of fimbrin binding to F-actin and its implications for filament crosslinking and regulation.
Nature structural biology 1998;5(9):787-92.
1998: Eads J C; Mahoney N M; Vorobiev S; Bresnick A R; Wen K K; Rubenstein P A; Haarer B K; Almo S C
Structure determination and characterization of Saccharomyces cerevisiae profilin.
Biochemistry 1998;37(32):11171-81.
1998: Mitra J; Tang X; Almo S C; Shields D
Temperature-induced conformational changes in prosomatostatin-II: implications for processing.
The Biochemical journal 1998;334 ( Pt 1)():275-82.
1998: Valenta R; Almo S; Ball T; Dolecek C; Steinberger P; Laffer S; Eibensteiner P; Flicker S; Vrtala S; Spitzauer S; Valent P; Denepoux S; Kraft D; Banchereau J; Lebecque S
The immunoglobulin E-allergen interaction: a target for therapy of type I allergic diseases.
International archives of allergy and immunology 1998;116(3):167-76.
1998: Puius Y A; Zou M; Ho N T; Ho C; Almo S C
Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp).
Biochemistry 1998;37(26):9258-65.
1998: Patskovska L N; Fedorov A A; Patskovsky Y V; Almo S C; Listowsky I
Expression, crystallization and preliminary X-ray analysis of ligand-free human glutathione S-transferase M2-2.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 3):458-60.
1998: Mao C; Cook W J; Zhou M; Federov A A; Almo S C; Ealick S E
Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry 1998;37(20):7135-46.
1998: Degano M; Almo S C; Sacchettini J C; Schramm V L
Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor.
Biochemistry 1998;37(18):6277-85.
1998: Puius Y A; Mahoney N M; Almo S C
The modular structure of actin-regulatory proteins.
Current opinion in cell biology 1998;10(1):23-34.
1998: Mahoney N M; Almo S C
Crystallization and preliminary X-ray analysis of human platelet profilin complexed with an oligo proline peptide.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 1):108-10.
1997: Puius Y A; Zhao Y; Sullivan M; Lawrence D S; Almo S C; Zhang Z Y
Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13420-5.
1997: Mahoney N M; Janmey P A; Almo S C
Structure of the profilin-poly-L-proline complex involved in morphogenesis and cytoskeletal regulation.
Nature structural biology 1997;4(11):953-60.
1997: Lappalainen P; Fedorov E V; Fedorov A A; Almo S C; Drubin D G
Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis.
The EMBO journal 1997;16(18):5520-30.
1997: Goldsmith S C; Pokala N; Shen W; Fedorov A A; Matsudaira P; Almo S C
The structure of an actin-crosslinking domain from human fimbrin.
Nature structural biology 1997;4(9):708-12.
1997: Goldsmith S C; Pokala N; Matsudaira P; Almo S C
Crystallization and preliminary crystallographic analysis of the N-terminal actin binding domain of human fimbrin.
Proteins 1997;28(3):452-3.
1997: Fedorov A A; Lappalainen P; Fedorov E V; Drubin D G; Almo S C
Structure determination of yeast cofilin.
Nature structural biology 1997;4(5):366-9.
1997: Fedorov A A; Ball T; Valenta R; Almo S C
X-ray crystal structures of birch pollen profilin and Phl p 2.
International archives of allergy and immunology 1997;113(1-3):109-13.
1997: Fedorov A A; Ball T; Mahoney N M; Valenta R; Almo S C
The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin.
Structure (London, England : 1993) 1997;5(1):33-45.
1996: Fedorov A A; Joseph-McCarthy D; Fedorov E; Sirakova D; Graf I; Almo S C
Ionic interactions in crystalline bovine pancreatic ribonuclease A.
Biochemistry 1996;35(50):15962-79.
1996: Wiedemann P; Giehl K; Almo S C; Fedorov A A; Girvin M; Steinberger P; Rüdiger M; Ortner M; Sippl M; Dolecek C; Kraft D; Jockusch B; Valenta R
Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody.
The Journal of biological chemistry 1996;271(47):29915-21.
1996: Joseph-McCarthy D; Fedorov A A; Almo S C
Comparison of experimental and computational functional group mapping of an RNase A structure: implications for computer-aided drug design.
Protein engineering 1996;9(9):773-80.
1994: Fedorov A A; Magnus K A; Graupe M H; Lattman E E; Pollard T D; Almo S C
X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8636-40.
1994: Fedorov A A; Pollard T D; Almo S C
Purification, characterization and crystallization of human platelet profilin expressed in Escherichia coli.
Journal of molecular biology 1994;241(3):480-2.
1994: Almo S C; Smith D L; Danishefsky A T; Ringe D
The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli.
Protein engineering 1994;7(3):405-12.
1994: Almo S C; Pollard T D; Way M; Lattman E E
Purification, characterization and crystallization of Acanthamoeba profilin expressed in Escherichia coli.
Journal of molecular biology 1994;236(3):950-2.
1994: Pollard T D; Almo S; Quirk S; Vinson V; Lattman E E
Structure of actin binding proteins: insights about function at atomic resolution.
Annual review of cell biology 1994;10():207-49.
1992: Howell P L; Almo S C; Parsons M R; Hajdu J; Petsko G A
Structure determination of turkey egg-white lysozyme using Laue diffraction data.
Acta crystallographica. Section B, Structural science 1992;48 ( Pt 2)():200-7.
1990: Schlichting I; Almo S C; Rapp G; Wilson K; Petratos K; Lentfer A; Wittinghofer A; Kabsch W; Pai E F; Petsko G A
Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.
Nature 1990;345(6273):309-15.
1989: Smith D L; Almo S C; Toney M D; Ringe D
2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli.
Biochemistry 1989;28(20):8161-7.
1989: Mondragón A; Subbiah S; Almo S C; Drottar M; Harrison S C
Structure of the amino-terminal domain of phage 434 repressor at 2.0 A resolution.
Journal of molecular biology 1989;205(1):189-200.
1988: Farber G K; Machin P; Almo S C; Petsko G A; Hajdu J
X-ray Laue diffraction from crystals of xylose isomerase.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):112-5.

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