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Steven Almo

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Kiryl D Piatkevich; Steven C Almo; Vladimir N Malashkevich; Kateryna S Morozova; Nicolai A Nemkovich; Vladislav V Verkhusha
Extended Stokes Shift in Fluorescent Proteins: Chromophore-Protein Interactions in a Near-Infrared TagRFP675 Variant.
Vladimir Vigdorovich; Xingxing Zang; Kimberly A Hofmeyer; Eszter Lazar-Molnar; Jun Sik Lee; Stanley G Nathenson; Udupi A Ramagopal; Eliezer Sylvestre; Steven C Almo
Structure and T cell inhibition properties of b7 family member, b7-h3.
Rotem Rubinstein; Steven C Almo; Stanley G Nathenson; Udupi A Ramagopal; Andras Fiser
Functional classification of immune regulatory proteins.

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All Publications

2013: Kiryl D Piatkevich; Steven C Almo; Vladimir N Malashkevich; Kateryna S Morozova; Nicolai A Nemkovich; Vladislav V Verkhusha
Extended Stokes Shift in Fluorescent Proteins: Chromophore-Protein Interactions in a Near-Infrared TagRFP675 Variant.
Scientific reports 2013;3():1847.
2013: Vladimir Vigdorovich; Xingxing Zang; Kimberly A Hofmeyer; Eszter Lazar-Molnar; Jun Sik Lee; Stanley G Nathenson; Udupi A Ramagopal; Eliezer Sylvestre; Steven C Almo
Structure and T cell inhibition properties of b7 family member, b7-h3.
Structure (London, England : 1993) 2013;21(5):707-17.
2013: Rotem Rubinstein; Steven C Almo; Stanley G Nathenson; Udupi A Ramagopal; Andras Fiser
Functional classification of immune regulatory proteins.
Structure (London, England : 1993) 2013;21(5):766-76.
2013: Parthasrathy Sampathkumar; J Michael Sauder; David L Stokes; Benjamin L Timney; Paula Upla; Thomas M Weiss; Jeffrey B Bonanno; Stephen K Burley; Javier Fernandez-Martinez; Zhanna Hakhverdyan; Natalia E Ketaren; Seung Joong Kim; Tsutomu Matsui; Jeremy Phillips; Ursula Pieper; William J Rice; Michael P Rout; Andrej Sali; Steven C Almo
Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.
Structure (London, England : 1993) 2013;21(4):560-71.
2013: Frank H Wallrapp; Gurusankar Ramamoorthy; Ronald Seidel; Steven C Almo; Daniel Almonacid; Patricia C Babbitt; Brandan S Hillerich; Matthew P Jacobson; Jian-Jung Pan; Yury Patskovsky; C Dale Poulter
Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(13):E1196-202.
2013: Ian Cook; Charles N Falany; Jungwook Kim; Steven C Almo; Ting Wang; Thomas S Leyh
Testing the sulfotransferase molecular pore hypothesis.
The Journal of biological chemistry 2013;288(12):8619-26.
2013: Whitney F Kellett; Ursula Rothlisberger; Steven C Almo; Elizabeth Brunk; Bijoy J Desai; Alexander A Fedorov; John A Gerlt; Nigel G J Richards
Computational, structural, and kinetic evidence that Vibrio vulnificus FrsA is not a cofactor-independent pyruvate decarboxylase.
Biochemistry 2013;52(11):1842-4.
2013: Javier Suarez; Funing Yan; Steven C Almo; Sean M Cahill; Antti M Haapalainen; Meng-Chiao Ho; Vern L Schramm
Catalytic site conformations in human PNP by 19F-NMR and crystallography.
Chemistry & biology 2013;20(2):212-22.
2013: Swapnil V Ghodge; Brandan Hillerich; Steven C Almo; Alexander A Fedorov; Elena V Fedorov; Ronald Seidel; Frank M Raushel
Structural and mechanistic characterization of L-histidinol phosphate phosphatase from the polymerase and histidinol phosphatase family of proteins.
Biochemistry 2013;52(6):1101-12.
2013: Hao Fan; Brandan Hillerich; Daniel S Hitchcock; Henry Lin; Andrej Sali; Ronald D Seidel; Brian K Shoichet; Steven C Almo; Frank M Raushel
Assignment of pterin deaminase activity to an enzyme of unknown function guided by homology modeling and docking.
Journal of the American Chemical Society 2013;135(2):795-803.
2013: Ian Cook; Charles N Falany; Jungwook Kim; Steven C Almo; Ting Wang; Thomas S Leyh
The gate that governs sulfotransferase selectivity.
Biochemistry 2013;52(2):415-24.
2013: Merlin Eric Hobbs; Devon M Kebodeaux; Tamari Narindoshvili; Steven C Almo; Brandan Hillerich; Ronald D Seidel; Matthew W Vetting; Howard J Williams; Frank M Raushel
Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily.
Biochemistry 2013;52(1):239-53.
2013: Jungwook Kim; Steven C Almo
Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC.
BMC structural biology 2013;13(1):5.
2013: Meng-Chiao Ho; P Rajesh Kumar; Tsutomu Matsui; Takashi Onikubo; Ulf Reimer; Janina Jansong; Steven C Almo; Jeffrey B Bonanno; Michael Brenowitz; Lester G Carter; Man K Chan; R Holland Cheng; Carola Wilczek; Li Xing; David Shechter
Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.
PloS one 2013;8(2):e57008.
2012: Rong Guan; Meng-Chiao Ho; Steven C Almo; Richard F G Fröhlich; Peter C Tyler; Vern L Schramm
Methylthioadenosine deaminase in an alternative quorum sensing pathway in Pseudomonas aeruginosa.
Biochemistry 2012;51(45):9094-103.
2012: Erin L Garside; Emily M Gesner; Steven C Almo; Jeffrey B Bonanno; Stephen K Burley; Garima Mehta; J Michael Sauder; Matthew J Schellenberg; Andrew M MacMillan
Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases.
RNA (New York, N.Y.) 2012;18(11):2020-8.
2012: Bijoy J Desai; Alexander A Fedorov; Elena V Fedorov; Steven C Almo; Tina L Amyes; Bogdana Goryanova; John Patrick Richard; B McKay Wood; John Alan Gerlt
Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
Biochemistry 2012;51(43):8665-78.
2012: Benjamin P Warlick; Steven C Almo; Jeffrey B Bonanno; Stephen K Burley; Tobias J Erb; Bradley S Evans; Heidi J Imker; Udupi A Ramagopal; J Michael Sauder; Jaya Sriram; Jonathan S Sweedler; F Robert Tabita; John Alan Gerlt
1-methylthio-D-xylulose 5-phosphate methylsulfurylase: a novel route to 1-deoxy-D-xylulose 5-phosphate in Rhodospirillum rubrum.
Biochemistry 2012;51(42):8324-6.
2012: Jayne F Koellhoffer; Vladimir N Malashkevich; Rafael Toro; Steven C Almo; Rahul C Bhosle; Kartik Chandran; Joseph S Harrison; Jonathan Lai
Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation.
Biochemistry 2012;51(39):7665-75.
2012: Dibyendu Samanta; Vladimir Vigdorovich; Stanley G Nathenson; Udupi A Ramagopal; Rotem Rubinstein; Steven C Almo
Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(37):14836-40.
2012: Shanzhi Wang; Funing Yan; Peter C Tyler; Steven C Almo; Rosemary L Brown; Quan Du; Gary B Evans; Antti M Haapalainen; Gillian E Norris; Agnes Rinaldo-Matthis; Vern L Schramm
A picomolar transition state analogue inhibitor of MTAN as a specific antibiotic for Helicobacter pylori.
Biochemistry 2012;51(35):6892-4.
2012: Parthasrathy Sampathkumar; J Michael Sauder; Devon A Thompson; Hiro Tsuruta; Stephen R Wasserman; Steven C Almo; Shane Atwell; Kevin T Bain; J Spencer Emtage; Javier Fernandez-Martinez; Josef D Franke; Tarun Gheyi; Jeremiah Gilmore; Seung Joong Kim; Danalyn Manglicmot; Tsutomu Matsui; Jeremy Phillips; Ursula Pieper; Michael P Rout; Andrej Sali; Stephen K Burley
Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
Proteins 2012;80(8):2110-6.
2012: Keith Z Hazleton; Meng-Chiao Ho; Emilio F Merino; Irving Rosario; Steven C Almo; Maria Cassera; Keith Clinch; Douglas R Crump; Peter C Tyler; Vern L Schramm
Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Chemistry & biology 2012;19(6):721-30.
2012: Charles Grubmeyer; Michael Riis Hansen; Alexander A Fedorov; Steven C Almo
Structure of Salmonella typhimurium OMP synthase in a complete substrate complex.
Biochemistry 2012;51(22):4397-405.
2012: Merlin Eric Hobbs; Vladimir N Malashkevich; Steven C Almo; Stephen K Burley; J Michael Sauder; Howard J Williams; Chengfu Xu; Frank M Raushel
Structure and catalytic mechanism of LigI: insight into the amidohydrolase enzymes of cog3618 and lignin degradation.
Biochemistry 2012;51(16):3497-507.
2012: Tiit Lukk; Satish K Nair; Yury Patskovsky; Ayano Sakai; Ronald Seidel; Ling Song; Rafael Toro; Matthew W Vetting; Steven C Almo; Patricia C Babbitt; Shoshana D Brown; Alexander A Fedorov; Elena V Fedorov; John Alan Gerlt; Brandan S. Hillerich; Heidi J Imker; Chakrapani Kalyanaraman; Matthew P Jacobson
Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(11):4122-7.
2012: Dao Feng Xiang; Chengfu Xu; Brian Shoichet; Howard J Williams; Steven C Almo; Alexander A Fedorov; Elena V Fedorov; Peter Kolb; Tamari Narindoshivili; Frank M Raushel
Structure-based function discovery of an enzyme for the hydrolysis of phosphorylated sugar lactones.
Biochemistry 2012;51(8):1762-73.
2012: John Alan Gerlt; Patricia C Babbitt; Matthew P Jacobson; Steven C Almo
Divergent evolution in enolase superfamily: strategies for assigning functions.
The Journal of biological chemistry 2012;287(1):29-34.
2012: Vivek L Patel; Adina R Buxbaum; Richard Harris; Steven C Almo; Michael Brenowitz; Timothée Lionnet; Matthew Levy; Somdeb Mitra; Mark E Girvin; Robert H Singer; Jeffrey A. Chao
Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control.
Genes & development 2012;26(1):43-53.
2011: Rong Guan; Meng-Chiao Ho; Steven C Almo; Michael Brenowitz; Gary B Evans; Peter C Tyler; Vern L Schramm
Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.
Biochemistry 2011;50(47):10408-17.
2011: John Alan Gerlt; Heidi J Imker; Matthew P Jacobson; Wladek Minor; C Dale Poulter; Frank M Raushel; Andrej Sali; Brian K Shoichet; Karen N Allen; Steven C Almo; Richard N Armstrong; Patricia C Babbitt; John E Cronan; Debra Dunaway-Mariano; Jonathan V Sweedler
The Enzyme Function Initiative.
Biochemistry 2011;50(46):9950-62.
2011: Hua Huang; Chetanya Pandya; Yury Patskovsky; Rafael Toro; Karen N Allen; Steven C Almo; Jeremiah D Farelli; Debra Dunaway-Mariano
Divergence of structure and function in the haloacid dehalogenase enzyme superfamily: Bacteroides thetaiotaomicron BT2127 is an inorganic pyrophosphatase.
Biochemistry 2011;50(41):8937-49.
2011: Vanessa Iiams; Steven C Almo; Bijoy J Desai; Alexander A Fedorov; Elena V Fedorov; John Alan Gerlt
Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site.
Biochemistry 2011;50(39):8497-507.
2011: Natalya G Dulyaninova; Karen M Hite; Dominic A Scudiero; Robert H Shoemaker; Wendy D Zencheck; Steven C Almo; Anne R Bresnick
Cysteine 81 is critical for the interaction of S100A4 and myosin-IIA.
Biochemistry 2011;50(33):7218-27.
2011: Dibyendu Samanta; Rodolfo J. Chaparro; Teresa P DiLorenzo; Gayatri Mukherjee; Stanley G Nathenson; Udupi A Ramagopal; Steven C Almo
Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(33):13682-7.
2011: Camille Roche; Vladimir N Malashkevich; Juan Moreira; Steven C Almo; Tatiana C Balazs; Qiuying Chen; David Dantsker; Joel Mitchel Friedman; Rhoda Elison Hirsch
Structural and functional studies indicating altered redox properties of hemoglobin E: implications for production of bioactive nitric oxide.
The Journal of biological chemistry 2011;286(26):23452-66.
2011: Maria L B Magalhães; Vladimir N Malashkevich; Steven C Almo; Clarissa Melo Czekster; Rong Guan; Matthew Levy
Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.
Protein science : a publication of the Protein Society 2011;20(7):1145-54.
2011: Daniel S Hitchcock; Steven C Almo; Lawrence J Dangott; Alexander A Fedorov; Elena V Fedorov; Frank M Raushel
Rescue of the orphan enzyme isoguanine deaminase.
Biochemistry 2011;50(25):5555-7.
2011: Richard Hall; Alexander A Fedorov; Chengfu Xu; Elena V Fedorov; Steven C Almo; Frank M Raushel
Three-dimensional structure and catalytic mechanism of cytosine deaminase.
Biochemistry 2011;50(22):5077-85.
2011: Maria Cassera; Meng-Chiao Ho; Emilio F Merino; Emmanuel Burgos ; Agnes Rinaldo-Matthis; Steven C Almo; Vern L Schramm
A high-affinity adenosine kinase from Anopheles gambiae.
Biochemistry 2011;50(11):1885-93.
2011: Li Wang; Rotem Rubinstein; Janet L Lines; Anna Wasiuk; Cory L Ahonen; Yanxia Guo; Li-Fan Lu; David Gondek; Yan Wang; Roy A Fava; András Fiser; Steven C Almo; Randolph J Noelle
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses.
The Journal of experimental medicine 2011;208(3):577-92.
2011: Rong Guan; Meng-Chiao Ho; Steven C Almo; Vern L Schramm
Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing.
Biochemistry 2011;50(7):1247-54.
2011: Chenyang Zhan; Yury Patskovsky; Qingrong Yan; Zhenhong Li; Udupi A Ramagopal; Huiyong Cheng; Michael Brenowitz; Hui Xiao; Stanley G Nathenson; Steven C Almo
Decoy strategies: the structure of TL1A:DcR3 complex.
Structure (London, England : 1993) 2011;19(2):162-71.
2011: Maria Cassera; Richard DePinto; Gary B Evans; Jemy A Gutierrez; Keith Z Hazleton; Meng-Chiao Ho; Emilio F Merino; Andrew S Murkin; Nicanor Obaldia; Steven C Almo; Yarlagadda S Babu; Vern L Schramm
Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.
PloS one 2011;6(11):e26916.
2010: Goragot Wisedchaisri; David M Dranow; Thomas J Lie; Jeffrey B Bonanno; Yury Patskovsky; Sinem A Ozyurt; J Michael Sauder; Steven C Almo; Stephen R Wasserman; Stephen K Burley; John A Leigh; Tamir Gonen
Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.
Structure (London, England : 1993) 2010;18(11):1512-21.
2010: Parthasrathy Sampathkumar; Frances Lu; Xun Zhao; Zhenzhen Li; Jeremiah Gilmore; Kevin Bain; Marc E Rutter; Tarun Gheyi; Kenneth D Schwinn; Jeffrey B Bonanno; Ursula Pieper; Jorge Fajardo; András Fiser; Steven C Almo; Subramanyam Swaminathan; Mark R Chance; David Baker; Shane Atwell; Devon A Thompson; J Spencer Emtage; Stephen R Wasserman; Andrej Sali; J Michael Sauder; Stephen K Burley
Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.
Proteins 2010;78(14):3056-62.
2010: Jennifer L Seffernick; Erik Reynolds; Alexander A Fedorov; Elena Fedorov; Steven C Almo; Michael J Sadowsky; Lawrence P Wackett
X-ray structure and mutational analysis of the atrazine Chlorohydrolase TrzN.
The Journal of biological chemistry 2010;285(40):30606-14.
2010: Ping-Chuan Tsai; Yubo Fan; Jungwook Kim; Lijiang Yang; Steven C Almo; Yi Qin Gao; Frank M Raushel
Structural determinants for the stereoselective hydrolysis of chiral substrates by phosphotriesterase.
Biochemistry 2010;49(37):7988-97.
2010: Kiryl D Piatkevich; Vladimir N Malashkevich; Steven C Almo; Vladislav Verkhusha
Engineering ESPT pathways based on structural analysis of LSSmKate red fluorescent proteins with large Stokes shift.
Journal of the American Chemical Society 2010;132(31):10762-70.
2010: Dao Feng Xiang; Yury Patskovsky; Chengfu Xu; Alexander A Fedorov; Elena V Fedorov; Abby A Sisco; J Michael Sauder; Stephen K Burley; Steven C Almo; Frank M Raushel
Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily .
Biochemistry 2010;49(31):6791-803.
2010: Zhong-Hua Li; Natalya G Dulyaninova; Reniqua P House; Steven C Almo; Anne R Bresnick
S100A4 regulates macrophage chemotaxis.
Molecular biology of the cell 2010;21(15):2598-610.
2010: Eszter Lazar-Molnar; Bing Chen; Kari A Sweeney; Emilie J Wang; Weijun Liu; Juan Lin; Steven A Porcelli; Steven C Almo; Stanley G Nathenson; William R. Jacobs Jr.
Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(30):13402-7.
2010: Reza Sharifi Sedeh; Alexander A Fedorov; Elena V Fedorov; Shoichiro Ono; Fumio Matsumura; Steven C Almo; Mark Bathe
Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein.
Journal of molecular biology 2010;400(3):589-604.
2010: Robert L Hudkins; Allison L Zulli; Ted L Underiner; Thelma S Angeles; Lisa D Aimone; Sheryl L Meyer; Daniel Pauletti; Hong Chang; Elena V Fedorov; Steven C Almo; Alexander A Fedorov; Bruce Ruggeri
8-THP-DHI analogs as potent Type I dual TIE-2/VEGF-R2 receptor tyrosine kinase inhibitors.
Bioorganic & medicinal chemistry letters 2010;20(11):3356-60.
2010: Vladimir N Malashkevich; Natalya G Dulyaninova; Udupi A Ramagopal; Melissa A Liriano; Kristen M Varney; David Knight; Michael Brenowitz; David Weber; Steven C Almo; Anne R Bresnick
Phenothiazines inhibit S100A4 function by inducing protein oligomerization.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(19):8605-10.
2010: B McKay Wood; Tina L Amyes; Alexander A Fedorov; Elena V Fedorov; Andrew Shabila; Steven C Almo; John Patrick Richard; John Alan Gerlt
Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation.
Biochemistry 2010;49(17):3514-6.
2010: Oksana M Subach; Vladimir N Malashkevich; Wendy D Zencheck; Kateryna S Morozova; Kiryl D Piatkevich; Steven C Almo; Vladislav Verkhusha
Structural characterization of acylimine-containing blue and red chromophores in mTagBFP and TagRFP fluorescent proteins.
Chemistry & biology 2010;17(4):333-41.
2010: Meng-Chiao Ho; Wuxian Shi; Agnes Rinaldo-Matthis; Peter C Tyler; Gary B Evans; Keith Clinch; Steven C Almo; Vern L Schramm
Four generations of transition-state analogues for human purine nucleoside phosphorylase.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(11):4805-12.
2010: Daniel R Brims; Jie Qian; Irene Jarchum; Leann Mikesh; Edith Palmieri; Udupi A Ramagopal; Vladimir N Malashkevich; Rodolfo J. Chaparro; Torben Lund; Masakazu Hattori; Jeffrey Shabanowitz; Donald F Hunt; Stanley G Nathenson; Steven C Almo; Teresa P DiLorenzo
Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
International immunology 2010;22(3):191-203.
2010: Jacqueline M Achkar; Elizabeth R Jenny-Avital; Xian Yu; Susanne Burger; Eric Leibert; Patrick W Bilder; Steven C Almo; Arturo Casadevall; Suman Laal
Antibodies against immunodominant antigens of Mycobacterium tuberculosis in subjects with suspected tuberculosis in the United States compared by HIV status.
Clinical and vaccine immunology : CVI 2010;17(3):384-92.
2010: Richard Hall; Alexander A Fedorov; Ricardo Marti-Arbona; Elena V Fedorov; Peter Kolb; J Michael Sauder; Stephen K Burley; Brian Shoichet; Steven C Almo; Frank M Raushel
The hunt for 8-oxoguanine deaminase.
Journal of the American Chemical Society 2010;132(6):1762-3.
2010: Sumeena Bhatia; Kristine Sun; Steven C Almo; Stanley G Nathenson; Richard J Hodes
Dynamic equilibrium of B7-1 dimers and monomers differentially affects immunological synapse formation and T cell activation in response to TCR/CD28 stimulation.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1821-8.
2010: Jennifer A Cummings; Tinh T Nguyen; Alexander A Fedorov; Peter Kolb; Chengfu Xu; Elena V Fedorov; Brian Shoichet; David P Barondeau; Steven C Almo; Frank M Raushel
Structure, mechanism, and substrate profile for Sco3058: the closest bacterial homologue to human renal dipeptidase .
Biochemistry 2010;49(3):611-22.
2010: Jeffrey A. Chao; Yury Patskovsky; Vivek Patel; Matthew Levy; Steven C Almo; Robert H Singer
ZBP1 recognition of beta-actin zipcode induces RNA looping.
Genes & development 2010;24(2):148-58.
2009: Fedor V. Subach; Vladimir N Malashkevich; Wendy D Zencheck; Hui Xiao; Grigory S Filonov; Steven C Almo; Vladislav Verkhusha
Photoactivation mechanism of PAmCherry based on crystal structures of the protein in the dark and fluorescent states.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(50):21097-102.
2009: John F Rakus; Chakrapani Kalyanaraman; Alexander A Fedorov; Elena V Fedorov; Fiona P Mills-Groninger; Rafael Toro; Jeffrey B Bonanno; Kevin Bain; J Michael Sauder; Stephen K Burley; Steven C Almo; Matthew P Jacobson; John Alan Gerlt
Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis .
Biochemistry 2009;48(48):11546-58.
2009: Meng-Chiao Ho; Matthew B Sturm; Steven C Almo; Vern L Schramm
Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(48):20276-81.
2009: John Jeff Alvarado; Anjana-Devi Nemkal; J Michael Sauder; Marijane Russell; Donna E Akiyoshi; Wuxian Shi; Steven C Almo; Louis M Weiss
Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.
Molecular and biochemical parasitology 2009;168(2):158-67.
2009: Liliana M Sampaleanu; Jeffrey B Bonanno; Melissa Ayers; J Koo; S Tammam; S K Burley; Steven C Almo; Lori L Burrows; P Lynne Howell
Periplasmic domains of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex.
Journal of molecular biology 2009;394(1):143-59.
2009: Meng-Chiao Ho; Maria Cassera; Dennis C Madrid; Li-Min Ting; Peter C Tyler; Kami Kim; Steven C Almo; Vern L Schramm
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.
Biochemistry 2009;48(40):9618-26.
2009: Tinh T Nguyen; Alexander A Fedorov; Lakenya Williams; Elena V Fedorov; Yingchun Li; Chengfu Xu; Steven C Almo; Frank M Raushel
The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.
Biochemistry 2009;48(37):8879-90.
2009: Emmanuel Burgos ; Meng-Chiao Ho; Steven C Almo; Vern L Schramm
A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):13748-53.
2009: Chenyang Zhan; Qingrong Yan; Yury Patskovsky; Zhenhong Li; Rafael Toro; Amanda Meyer; Huiyong Cheng; Michael Brenowitz; Stanley G Nathenson; Steven C Almo
Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry 2009;48(32):7636-45.
2009: Wendy D Zencheck; Hui Xiao; Brad J Nolen; Ruth Hogue Angeletti; Thomas D Pollard; Steven C Almo
Nucleotide- and activator-dependent structural and dynamic changes of arp2/3 complex monitored by hydrogen/deuterium exchange and mass spectrometry.
Journal of molecular biology 2009;390(3):414-27.
2009: Jennifer A Cummings; Alexander A Fedorov; Chengfu Xu; Shoshana Brown; Elena V Fedorov; Patricia C Babbitt; Steven C Almo; Frank M Raushel
Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.
Biochemistry 2009;48(27):6469-81.
2009: Kui K Chan; B McKay Wood; Alexander A Fedorov; Elena V Fedorov; Heidi J Imker; Tina L Amyes; John Patrick Richard; Steven C Almo; John Alan Gerlt
Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization.
Biochemistry 2009;48(24):5518-31.
2009: Dao Feng Xiang; Yury Patskovsky; Chengfu Xu; Amanda J Meyer; J Michael Sauder; Stephen K Burley; Steven C Almo; Frank M Raushel
Functional identification of incorrectly annotated prolidases from the amidohydrolase superfamily of enzymes.
Biochemistry 2009;48(17):3730-42.
2009: Joshua E Drumm; Kaixia Mi; Patrick Bilder; Meihao Sun; Jihyeon Lim; Helle Bielefeldt-Ohmann; Randall Basaraba; Melvin So; Guofeng Zhu; JoAnn M Tufariello; Angelo A Izzo; Ian M Orme; Steven C Almo; Thomas S Leyh; John Chan
Mycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infection.
PLoS pathogens 2009;5(5):e1000460.
2009: Kausik Chattopadhyay; Eszter Lazar-Molnar; Qingrong Yan; Rotem Rubinstein; Chenyang Zhan; Vladimir Vigdorovich; Udupi A Ramagopal; Jeffrey B Bonanno; Stanley G Nathenson; Steven C Almo
Sequence, structure, function, immunity: structural genomics of costimulation.
Immunological reviews 2009;229(1):356-86.
2009: Kausik Chattopadhyay; Udupi A Ramagopal; Stanley G Nathenson; Steven C Almo
1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 5):434-9.
2009: Jemy A Gutierrez; Tamara Crowder; Agnes Rinaldo-Matthis; Meng-Chiao Ho; Steven C Almo; Vern L Schramm
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
Nature chemical biology 2009;5(4):251-7.
2009: Tanja Ball; Birgit Linhart; Karoline Sonneck; K Blatt; H Herrmann; Peter Valent; Angelika Stoecklinger; C Lupinek; Josef Thalhamer; Alexander A Fedorov; Steven C Almo; Rudolf Valenta
Reducing allergenicity by altering allergen fold: a mosaic protein of Phl p 1 for allergy vaccination.
Allergy 2009;64(4):569-80.
2009: Ursula Pieper; Ranyee Chiang; Jennifer J Seffernick; Shoshana D Brown; Margaret E Glasner; Libusha Kelly; Narayanan Eswar; J Michael Sauder; Jeffrey B Bonanno; Subramanyam Swaminathan; Stephen K Burley; Xiaojing Zheng; Mark R Chance; Steven C Almo; John Alan Gerlt; Frank M Raushel; Matthew P Jacobson; Patricia C Babbitt; Andrej Sali
Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies.
Journal of structural and functional genomics 2009;10(2):107-25.
2009: Petr Leiman; Marek Basler; Udupi A Ramagopal; Jeffrey B Bonanno; J Michael Sauder; Stefan Pukatzki; Stephen K Burley; Steven C Almo; John J Mekalanos
Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4154-9.
2009: Dao Feng Xiang; Peter Kolb; Alexander A Fedorov; Monika M Meier; Lena V Fedorov; T Tinh Nguyen; Reinhard Sterner; Steven C Almo; Brian Shoichet; Frank M Raushel
Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.
Biochemistry 2009;48(10):2237-47.
2009: Ayano Sakai; Alexander A Fedorov; Elena V Fedorov; Alexandra M Schnoes; Margaret E Glasner; Shoshana Brown; Marc E Rutter; Kevin Bain; Shawn Chang; Tarun Gheyi; J Michael Sauder; Stephen K Burley; Patricia C Babbitt; Steven C Almo; John Alan Gerlt
Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes.
Biochemistry 2009;48(7):1445-53.
2008: Chakrapani Kalyanaraman; Heidi J Imker; Alexander A Fedorov; Elena V Fedorov; Margaret E Glasner; Patricia C Babbitt; Steven C Almo; John Alan Gerlt; Matthew P Jacobson
Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening.
Structure (London, England : 1993) 2008;16(11):1668-77.
2008: Robert L Hudkins; James L Diebold; Ming Tao; Kurt A Josef; Chung Ho Park; Thelma S Angeles; Lisa D Aimone; Jean Husten; Mark A Ator; Sheryl L Meyer; Beverly P Holskin; John T Durkin; Alexander A Fedorov; Elena V Fedorov; Steven C Almo; Joanne R Mathiasen; Donna Bozyczko-Coyne; Michael Saporito; Richard W Scott; John Mallamo
Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models.
Journal of medicinal chemistry 2008;51(18):5680-9.
2008: John F Rakus; Alexander A Fedorov; Elena V Fedorov; Margaret E Glasner; BK Hubbard; Joseph D Delli; Patricia C Babbitt; Steven C Almo; John Alan Gerlt
Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase.
Biochemistry 2008;47(38):9944-54.
2008: Jungwook Kim; Ping-Chuan Tsai; Shi-Lu Chen; Fahmi Himo; Steven C Almo; Frank M Raushel
Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase.
Biochemistry 2008;47(36):9497-504.
2008: Kui K Chan; Alexander A Fedorov; Elena V Fedorov; Steven C Almo; John Alan Gerlt
Structural basis for substrate specificity in phosphate binding (beta/alpha)8-barrels: D-allulose 6-phosphate 3-epimerase from Escherichia coli K-12.
Biochemistry 2008;47(36):9608-17.
2008: Eszter Lazar-Molnar; Qingrong Yan; Erhu Cao; Udupi A Ramagopal; Stanley G Nathenson; Steven C Almo
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(30):10483-8.
2008: Vladimir N Malashkevich; Kristen M Varney; Sarah C. Garrett; Paul T Wilder; David Knight; Thomas H Charpentier; Udupi A Ramagopal; Steven C Almo; David Weber; Anne R Bresnick
Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA.
Biochemistry 2008;47(18):5111-26.
2008: Eszter Lazar-Molnar; Attila Gácser; Gordon J Freeman; Steven C Almo; Stanley G Nathenson; Joshua D Nosanchuk
The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2658-63.
2008: Susanne Gräslund; Pär Nordlund; Johan Weigelt; B Martin Hallberg; James Bray; Opher Gileadi; Stefan Knapp; Udo Oppermann; Cheryl Arrowsmith; Raymond Hui; Jinrong Ming; Sirano dhe-Paganon; Hee-won Park; Alexei Savchenko; Adelinda Yee; Aled Edwards; Renaud Vincentelli; Christian Cambillau; Rosalind Kim; Sung-Hou Kim; Zihe Rao; Yunyu Shi; Thomas C Terwilliger; Chang-Yub Kim; Li-Wei Hung; Geoffrey Waldo; Yoav Peleg; Shira Albeck; Tamar Unger; Orly Dym; Jaime Prilusky; Joel Sussman; Ray C Stevens; Scott A Lesley; Ian A Wilson; Andrzej Joachimiak; Frank Collart; Irina Dementieva; Mark I Donnelly; William H Eschenfeldt; Youngchang Kim; Lucy Stols; Ruying Wu; Min Zhou; Stephen K Burley; J Spencer Emtage; J Michael Sauder; Devon Thompson; Kevin Bain; John Luz; Tarun Gheyi; Fred Zhang; Shane Atwell; Steven C Almo; Jeffrey B Bonanno; András Fiser; Sivasubramanian Swaminathan; F William Studier; Mark R Chance; Andrej Sali; Thomas B Acton; Rong Xiao; Li Zhao; Li Chung Ma; John F Hunt; Liang Tong; Kellie Cunningham; Masayori Inouye; Stephen Anderson; haleema janjua; Ritu Shastry; Chi Kent Ho; Dongyan Wang; Huang Wang; Mei Jiang; Gaetano T Montelione; David I Stuart; Raymond J Owens; Susan Daenke; Anja Schütz; Udo Heinemann; Shigeyuki Yokoyama; Konrad Büssow; Kristin C Gunsalus
Protein production and purification.
Nature methods 2008;5(2):135-46.
2008: Tinh T Nguyen; Shoshana Brown; Alexander A Fedorov; Elena V Fedorov; Patricia C Babbitt; Steven C Almo; Frank M Raushel
At the periphery of the amidohydrolase superfamily: Bh0493 from Bacillus halodurans catalyzes the isomerization of D-galacturonate to D-tagaturonate.
Biochemistry 2008;47(4):1194-206.
2008: Agnes Rinaldo-Matthis; Andrew S Murkin; Udupi A Ramagopal; Keith Clinch; Simon P H Mee; Gary B Evans; Peter C Tyler; Richard H Furneaux; Steven C Almo; Vern L Schramm
L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
Journal of the American Chemical Society 2008;130(3):842-4.
2008: Kausik Chattopadhyay; Udupi A Ramagopal; Michael Brenowitz; Stanley G Nathenson; Steven C Almo
Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):635-40.
2008: Jeffrey A. Chao; Yury Patskovsky; Steven C Almo; Robert H Singer
Structural basis for the coevolution of a viral RNA-protein complex.
Nature structural & molecular biology 2008;15(1):103-5.
2007: Kausik Chattopadhyay; Udupi A Ramagopal; Arunika Mukhopadhaya; Vladimir N Malashkevich; Teresa P DiLorenzo; Michael Brenowitz; Stanley G Nathenson; Steven C Almo
Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19452-7.
2007: John F Rakus; Alexander A Fedorov; Elena V Fedorov; Margaret E Glasner; Jacob E Vick; Patricia C Babbitt; Steven C Almo; John Alan Gerlt
Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Biochemistry 2007;46(45):12896-908.
2007: Erika Taylor; Agnes Rinaldo-Matthis; Lei Li; Mahmoud Ghanem; Keith Z Hazleton; Maria Cassera; Steven C Almo; Vern L Schramm
Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
Biochemistry 2007;46(43):12405-15.
2007: Steven C Almo; Jeffrey B Bonanno; J Michael Sauder; Spencer Emtage; Teresa P DiLorenzo; Vladimir N Malashkevich; Steven R Wasserman; S Swaminathan; Subramaniam Eswaramoorthy; Rakhi Agarwal; Desigan Kumaran; Mahendra Madegowda; Sugadev Ragumani; Yury Patskovsky; Johnjeff Alvarado; Udupi A Ramagopal; Joana Faber-Barata; Mark R Chance; Andrej Sali; András Fiser; Zhong-Yin Zhang; David S Lawrence; Stephen K Burley
Structural genomics of protein phosphatases.
Journal of structural and functional genomics 2007;8(2-3):121-40.
2007: Wen Shan Yew; Alexander A Fedorov; Elena V Fedorov; Steven C Almo; John Alan Gerlt
Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Biochemistry 2007;46(33):9564-77.
2007: Johannes C Hermann; Ricardo Marti-Arbona; Alexander A Fedorov; Elena V Fedorov; Steven C Almo; Brian Shoichet; Frank M Raushel
Structure-based activity prediction for an enzyme of unknown function.
Nature 2007;448(7155):775-9.
2007: Susanne Vrtala; Margarete Focke; Jolanta Kopec; Petra Verdino; Arnulf Hartl; Wolfgang R Sperr; Alexander A Fedorov; Tanja Ball; Steven C Almo; Peter Valent; Josef Thalhamer; Walter Keller; Rudolf Valenta
Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1730-9.
2007: Ling Song; Chakrapani Kalyanaraman; Alexander A Fedorov; Elena V Fedorov; Margaret E Glasner; Shoshana Brown; Heidi J Imker; Patricia C Babbitt; Steven C Almo; Matthew P Jacobson; John Alan Gerlt
Prediction and assignment of function for a divergent N-succinyl amino acid racemase.
Nature chemical biology 2007;3(8):486-91.
2007: Richard Hall; Shoshana Brown; Alexander A Fedorov; Elena V Fedorov; Chengfu Xu; Patricia C Babbitt; Steven C Almo; Frank M Raushel
Structural diversity within the mononuclear and binuclear active sites of N-acetyl-D-glucosamine-6-phosphate deacetylase.
Biochemistry 2007;46(27):7953-62.
2007: Qingrong Yan; Vladimir N Malashkevich; Alexander A Fedorov; Elena V Fedorov; Erhu Cao; Jeffrey W Lary; James L Cole; Stanley G Nathenson; Steven C Almo
Structure of CD84 provides insight into SLAM family function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10583-8.
2007: Glendon D McLachlan; Sean M Cahill; Mark E Girvin; Steven C Almo
Acid-induced equilibrium folding intermediate of human platelet profilin.
Biochemistry 2007;46(23):6931-43.
2007: Andrew S Murkin; Matthew R Birck; Agnes Rinaldo-Matthis; Wuxian Shi; Erika Taylor; Steven C Almo; Vern L Schramm
Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry 2007;46(17):5038-49.
2007: Heidi J Imker; Alexander A Fedorov; Elena V Fedorov; Steven C Almo; John Alan Gerlt
Mechanistic diversity in the RuBisCO superfamily: the "enolase" in the methionine salvage pathway in Geobacillus kaustophilus.
Biochemistry 2007;46(13):4077-89.
2007: Philippe Velge; M Herler; J Johansson; Sylvie M Roche; S Témoin; Alexander A Fedorov; Patrice Gracieux; Steven C Almo; W Goebel; Pascale Cossart
A naturally occurring mutation K220T in the pleiotropic activator PrfA of Listeria monocytogenes results in a loss of virulence due to decreasing DNA-binding affinity.
Microbiology (Reading, England) 2007;153(Pt 4):995-1005.
2007: Erhu Cao; Xingxing Zang; Udupi A Ramagopal; Arunika Mukhopadhaya; Alexander A Fedorov; Elena V Fedorov; Wendy D Zencheck; Jeffrey W Lary; James L Cole; Haiteng Deng; Hui Xiao; Teresa P DiLorenzo; James P Allison; Stanley G Nathenson; Steven C Almo
T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface.
Immunity 2007;26(3):311-21.
2007: Janna G Kiselar; Rachel Mahaffy; Thomas D Pollard; Steven C Almo; Mark R Chance
Visualizing Arp2/3 complex activation mediated by binding of ATP and WASp using structural mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(5):1552-7.
2007: Agnes Rinaldo-Matthis; corin wing; Mahmoud Ghanem; Hua Deng; Peng Wu; Arti Gupta; Peter C Tyler; Gary B Evans; Richard H Furneaux; Steven C Almo; Ching C Wang; Vern L Schramm
Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Biochemistry 2007;46(3):659-68.
2007: Sabrina A Benchaar; Yongming Xie; Martin Phillips; Rachel R Ogorzalek Loo; Vitold E Galkin; Albina Orlova; Mario Thevis; Andras Muhlrad; Steven C Almo; Joseph A Loo; Edward H Egelman; Emil Reisler
Mapping the interaction of cofilin with subdomain 2 on actin.
Biochemistry 2007;46(1):225-33.
2006: Wen Shan Yew; Alexander A Fedorov; Elena V Fedorov; Bryant McKay Wood; Steven C Almo; John Alan Gerlt
Evolution of enzymatic activities in the enolase superfamily: D-tartrate dehydratase from Bradyrhizobium japonicum.
Biochemistry 2006;45(49):14598-608.
2006: Wen Shan Yew; Alexander A Fedorov; Elena V Fedorov; John F Rakus; Richard W Pierce; Steven C Almo; John Alan Gerlt
Evolution of enzymatic activities in the enolase superfamily: L-fuconate dehydratase from Xanthomonas campestris.
Biochemistry 2006;45(49):14582-97.
2006: Eszter Lazar-Molnar; Steven C Almo; Stanley G Nathenson
The interchain disulfide linkage is not a prerequisite but enhances CD28 costimulatory function.
Cellular immunology 2006;244(2):125-9.
2006: Vipender Singh; Wuxian Shi; Steven C Almo; Gary B Evans; Richard H Furneaux; Peter C Tyler; Gavin F Painter; Dirk H Lenz; Simon P H Mee; Renjian Zheng; Vern L Schramm
Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Biochemistry 2006;45(43):12929-41.
2006: Y Zhang; Sergey M Vorobiev; bruce gibson; Binghua Hao; Gurjit S Sidhu; Vishnu S Mishra; Elena G Yarmola; michael bubb; Steven C Almo; Frederick S Southwick
A CapG gain-of-function mutant reveals critical structural and functional determinants for actin filament severing.
The EMBO journal 2006;25(19):4458-67.
2006: Erhu Cao; Udupi A Ramagopal; Alexander A Fedorov; Elena V Fedorov; Qingrong Yan; Jeffrey W Lary; James L Cole; Stanley G Nathenson; Steven C Almo
NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family.
Immunity 2006;25(4):559-70.
2006: Kausik Chattopadhyay; Sumeena Bhatia; András Fiser; Steven C Almo; Stanley G Nathenson
Structural basis of inducible costimulator ligand costimulatory function: determination of the cell surface oligomeric state and functional mapping of the receptor binding site of the protein.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3920-9.
2006: Sabine Flicker; Peter Steinberger; Tanja Ball; Maria-Theresa Krauth; Petra Verdino; Peter Valent; Steven C Almo; Rudolf Valenta
Spatial clustering of the IgE epitopes on the major timothy grass pollen allergen Phl p 1: importance for allergenic activity.
The Journal of allergy and clinical immunology 2006;117(6):1336-43.
2006: Jungwook Kim; Vladimir N Malashkevich; Setu Roday; Michael Lisbin; Vern L Schramm; Steven C Almo
Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.
Biochemistry 2006;45(20):6407-16.
2006: Sumeena Bhatia; Michael Edidin; Steven C Almo; Stanley G Nathenson
B7-1 and B7-2: similar costimulatory ligands with different biochemical, oligomeric and signaling properties.
Immunology letters 2006;104(1-2):70-5.
2006: Yury Patskovsky; Larysa Patskovska; Steven C Almo; Irving Listowsky
Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry 2006;45(12):3852-62.
2006: Wah Chiu; Matthew Baker; Steven C Almo
Structural biology of cellular machines.
Trends in cell biology 2006;16(3):144-50.
2006: Matthew M Roden; Daniel R Brims; Alexander A Fedorov; Teresa P DiLorenzo; Steven C Almo; Stanley G Nathenson
Structural analysis of H2-Db class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: implications for the mechanism underlying variations in antigen presentation.
Molecular immunology 2006;43(9):1370-8.
2006: Julie Akana; Alexander A Fedorov; Elena V Fedorov; Walter R P Novak; Patricia C Babbitt; Steven C Almo; John Alan Gerlt
D-Ribulose 5-phosphate 3-epimerase: functional and structural relationships to members of the ribulose-phosphate binding (beta/alpha)8-barrel superfamily.
Biochemistry 2006;45(8):2493-503.
2005: Chenyang Zhan; Elena V Fedorov; Wuxian Shi; Udupi A Ramagopal; R Thirumuruhan; Babu A Manjasetty; Steven C Almo; András Fiser; Mark R Chance; Alexander A Fedorov
The ybeY protein from Escherichia coli is a metalloprotein.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 11):959-63.
2005: Sumeena Bhatia; Michael Edidin; Steven C Almo; Stanley G Nathenson
Different cell surface oligomeric states of B7-1 and B7-2: implications for signaling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15569-74.
2005: Tania Parsa; Sandra J Cunningham; Stephen P Wall; Steven C Almo; Ellen F Crain
The usefulness of urine fluorescence for suspected antifreeze ingestion in children.
The American journal of emergency medicine 2005;23(6):787-92.
2005: Jin-Peng Sun; Wei-Qing Wang; Heyi Yang; Sijiu Liu; Fubo Liang; Alexander A Fedorov; Steven C Almo; Zhong-Yin Zhang
Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion.
Biochemistry 2005;44(36):12009-21.
2005: Udupi A Ramagopal; Zbigniew Dauter; Radhakannan Thirumuruhan; Elena V Fedorov; Steven C Almo
Radiation-induced site-specific damage of mercury derivatives: phasing and implications.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 9):1289-98.
2005: Yiider Tseng; Thomas P Kole; Jerry S H Lee; Elena Fedorov; Steven C Almo; Benjamin Schafer; Denis Wirtz
How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response.
Biochemical and biophysical research communications 2005;334(1):183-92.
2005: Omar Quintero-Monzon; Avital A Rodal; Boris Strokopytov; Steven C Almo; Bruce L Goode
Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions.
Molecular biology of the cell 2005;16(7):3128-39.
2005: Natalya G Dulyaninova; Vladimir N Malashkevich; Steven C Almo; Anne R Bresnick
Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation.
Biochemistry 2005;44(18):6867-76.
2005: Larysa Patskovska; Yury Patskovsky; Steven C Almo; Rhoda Elison Hirsch
COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 5):566-73.
2005: Jing-Qu Guan; Keiji Takamoto; Steven C Almo; Emil Reisler; Mark R Chance
Structure and dynamics of the actin filament.
Biochemistry 2005;44(9):3166-75.
2005: Boris V Strokopytov; Alexander A Fedorov; Nicole Mahoney; Michael kessels; David G Drubin; Steven C Almo
Phased translation function revisited: structure solution of the cofilin-homology domain from yeast actin-binding protein 1 using six-dimensional searches.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 3):285-93.
2005: Jeffrey B Bonanno; Steven C Almo; Anne R Bresnick; Mark R Chance; András Fiser; S Swaminathan; J Jiang; F William Studier; Lawrence Shapiro; Christopher D Lima; Theresa M Gaasterland; Andrej Sali; Kevin Bain; Ingeborg K Feil; Xia Gao; Don Lorimer; Aurora Ramos; J Michael Sauder; Steven R Wasserman; Spencer Emtage; Kevin L D'Amico; Stephen K Burley
New York-Structural GenomiX Research Consortium (NYSGXRC): a large scale center for the protein structure initiative.
Journal of structural and functional genomics 2005;6(2-3):225-32.
2005: Tanja Ball; William Edstrom; Ludwig Mauch; Jacky Schmitt; Bernd Leistler; Helmut Fiebig; Wolfgang R Sperr; Alexander W Hauswirth; Peter Valent; Dietrich Kraft; Steven C Almo; Rudolf Valenta
Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1.
The FEBS journal 2005;272(1):217-27.
2004: Pieta K Mattila; Omar Quintero-Monzon; Jamie Kugler; James Moseley; Steven C Almo; Pekka Lappalainen; Bruce L Goode
A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein.
Molecular biology of the cell 2004;15(11):5158-71.
2004: Andras Muhlrad; Dmitri Kudryashov; Y Michael Peyser; Andrey A Bobkov; Steven C Almo; Emil Reisler
Cofilin induced conformational changes in F-actin expose subdomain 2 to proteolysis.
Journal of molecular biology 2004;342(5):1559-67.
2004: P Sukumvanich; Vera M. Des Marais; Corina Sarmiento; Yihong Wang; Ilia Ichetovkin; Ghassan mouneimne; Steven C Almo; John Condeelis
Cellular localization of activated N-WASP using a conformation-sensitive antibody.
Cell motility and the cytoskeleton 2004;59(2):141-52.
2004: Tetyana Dodatko; Alexander A Fedorov; Marcin Grynberg; Yury Patskovsky; Denise A Rozwarski; Lukasz Jaroszewski; Eliah Aronoff-Spencer; Elena Kondraskina; Tom Irving; Adam Godzik; Steven C Almo
Crystal structure of the actin binding domain of the cyclase-associated protein.
Biochemistry 2004;43(33):10628-41.
2004: Kurato Mohri; Sergeui Vorobiev; Alexander A Fedorov; Steven C Almo; Shoichiro Ono
Identification of functional residues on Caenorhabditis elegans actin-interacting protein 1 (UNC-78) for disassembly of actin depolymerizing factor/cofilin-bound actin filaments.
The Journal of biological chemistry 2004;279(30):31697-707.
2004: Michael G Klein; Wuxian Shi; Udupi A Ramagopal; Yiider Tseng; Denis Wirtz; David R Kovar; Christopher J Staiger; Steven C Almo
Structure of the actin crosslinking core of fimbrin.
Structure (London, England : 1993) 2004;12(6):999-1013.
2004: Wuxian Shi; Li-Min Ting; Gregory A Kicska; Andrzej Lewandowicz; Peter C Tyler; Gary B Evans; Richard H Furneaux; Kami Kim; Steven C Almo; Vern L Schramm
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.
The Journal of biological chemistry 2004;279(18):18103-6.
2004: Jing-Qu Guan; Steven C Almo; Mark R Chance
Synchrotron radiolysis and mass spectrometry: a new approach to research on the actin cytoskeleton.
Accounts of chemical research 2004;37(4):221-9.
2004: Andrey A Bobkov; Andras Muhlrad; Alexander Shvetsov; Sabrina A Benchaar; Damon Scoville; Steven C Almo; Emil Reisler
Cofilin (ADF) affects lateral contacts in F-actin.
Journal of molecular biology 2004;337(1):93-104.
2004: Xuewu Zhang; Jean-Claude D Schwartz; Xiaoling Guo; Sumeena Bhatia; Erhu Cao; Michael Lorenz; Michael Cammer; Lieping Chen; Zhong-Yin Zhang; Michael Edidin; Stanley G Nathenson; Steven C Almo
Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity 2004;20(3):337-47.
2004: Vipender Singh; Wuxian Shi; Gary B Evans; Peter C Tyler; Richard H Furneaux; Steven C Almo; Vern L Schramm
Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
Biochemistry 2004;43(1):9-18.
2003: Jing-Qu Guan; Steven C Almo; Emil Reisler; Mark R Chance
Structural reorganization of proteins revealed by radiolysis and mass spectrometry: G-actin solution structure is divalent cation dependent.
Biochemistry 2003;42(41):11992-2000.
2003: Janna G Kiselar; Paul A Janmey; Steven C Almo; Mark R Chance
Structural analysis of gelsolin using synchrotron protein footprinting.
Molecular & cellular proteomics : MCP 2003;2(10):1120-32.
2003: Jin-Peng Sun; Li Wu; Alexander A Fedorov; Steven C Almo; Zhong-Yin Zhang
Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor.
The Journal of biological chemistry 2003;278(35):33392-9.
2003: Raymond Y Huang; Simon J Boulton; Marc Vidal; Steven C Almo; Anne R Bresnick; Mark R Chance
High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins.
Biochemical and biophysical research communications 2003;307(4):928-34.
2003: Andrzej Lewandowicz; Wuxian Shi; Gary B Evans; Peter C Tyler; Richard H Furneaux; Luiz A Basso; Diogenes Santos; Steven C Almo; Vern L Schramm
Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Biochemistry 2003;42(20):6057-66.
2003: S Vorobiev; B Strokopytov; David G Drubin; C Frieden; S Ono; John Condeelis; Peter A Rubenstein; Steven C Almo
The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5760-5.
2003: Jin-Peng Sun; Alexander A Fedorov; Seung-Yub Lee; Xiao-Ling Guo; Kui Shen; David S Lawrence; Steven C Almo; Zhong-Yin Zhang
Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.
The Journal of biological chemistry 2003;278(14):12406-14.
2003: Janna G Kiselar; Paul A Janmey; Steven C Almo; Mark R Chance
Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3942-7.
2003: Xuewu Zhang; Jean-Claude D Schwartz; Steven C Almo; Stanley G Nathenson
Crystal structure of the receptor-binding domain of human B7-2: insights into organization and signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2586-91.
2002: Gregory A Kicska; Peter C Tyler; Gary B Evans; Richard H Furneaux; Wuxian Shi; Alexander A Fedorov; Andrzej Lewandowicz; Sean M Cahill; Steven C Almo; Vern L Schramm
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Biochemistry 2002;41(49):14489-98.
2002: John C Dewan; Angela R Feeling-Taylor; Yoram A Puius; Larysa Patskovska; Yury Patskovsky; Ronald L Nagel; Steven C Almo; Rhoda Elison Hirsch
Structure of mutant human carbonmonoxyhemoglobin C (betaE6K) at 2.0 A resolution.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):2038-42.
2002: Andrey A Bobkov; Andras Muhlrad; Kaveh Kokabi; Sergey Vorobiev; Steven C Almo; Emil Reisler
Structural effects of cofilin on longitudinal contacts in F-actin.
Journal of molecular biology 2002;323(4):739-50.
2002: Wuxian Shi; Anne E Sarver; Ching C Wang; Kelly S E Tanaka; Steven C Almo; Vern L Schramm
Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration.
The Journal of biological chemistry 2002;277(42):39981-8.
2002: Yiider Tseng; Benjamin Schafer; Steven C Almo; Denis Wirtz
Functional synergy of actin filament cross-linking proteins.
The Journal of biological chemistry 2002;277(28):25609-16.
2002: michael bubb; Lakshmanan Govindasamy; Elena G Yarmola; Sergey M Vorobiev; Steven C Almo; Thayumanasamy Somasundaram; Michael S Chapman; Mavis Agbandje-McKenna; Robert McKenna
Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
The Journal of biological chemistry 2002;277(23):20999-1006.
2002: Xuewu Zhang; Jean-Claude D Schwartz; Steven C Almo; Stanley G Nathenson
Expression, refolding, purification, molecular characterization, crystallization, and preliminary X-ray analysis of the receptor binding domain of human B7-2.
Protein expression and purification 2002;25(1):105-13.
2002: Jing-Qu Guan; Sergeui Vorobiev; Steven C Almo; Mark R Chance
Mapping the G-actin binding surface of cofilin using synchrotron protein footprinting.
Biochemistry 2002;41(18):5765-75.
2002: Jean-Claude D Schwartz; Xuewu Zhang; Stanley G Nathenson; Steven C Almo
Structural mechanisms of costimulation.
Nature immunology 2002;3(5):427-34.
2002: Mark R Chance; Anne R Bresnick; Stephen K Burley; Jian-Sheng Jiang; Christopher D Lima; Andrej Sali; Steven C Almo; Jeffrey B Bonanno; John A Buglino; Simon J Boulton; Hua Chen; Narayanan Eswar; Guoshun He; Raymond Huang; Valentin A Ilyin; Linda McMahan; Ursula Pieper; Soumya Ray; Marc Vidal; Li Kai Wang
Structural genomics: a pipeline for providing structures for the biologist.
Protein science : a publication of the Protein Society 2002;11(4):723-38.
2002: David A Ostrov; Matthew M Roden; Wuxian Shi; Edith Palmieri; Gregory J Christianson; Lisa Mendoza; Gilbert Villaflor; Darcie Tilley; Nilabh Shastri; Howard Grey; Steven C Almo; Derry C Roopenian; Stanley G Nathenson
How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):283-9.
2001: S C Goldsmith; Jing-Qu Guan; Steven C Almo; Mark R Chance
Synchrotron protein footprinting: a technique to investigate protein-protein interactions.
Journal of biomolecular structure & dynamics 2001;19(3):405-18.
2001: Wuxian Shi; Kelly S E Tanaka; TR Crother; Milton Taylor; Steven C Almo; Vern L Schramm
Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
Biochemistry 2001;40(36):10800-9.
2001: Wuxian Shi; Luiz A Basso; Diogenes Santos; Peter C Tyler; Richard H Furneaux; John S Blanchard; Steven C Almo; Vern L Schramm
Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry 2001;40(28):8204-15.
2001: Yiider Tseng; Elena Fedorov; J M McCaffery; Steven C Almo; Denis Wirtz
Micromechanics and ultrastructure of actin filament networks crosslinked by human fascin: a comparison with alpha-actinin.
Journal of molecular biology 2001;310(2):351-66.
2001: Xuewu Zhang; Jean-Claude D Schwartz; Stanley G Nathenson; Steven C Almo
Crystallization and preliminary X-ray analysis of the complex between human CTLA-4 and B7-2.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 6):898-9.
2001: Richard R Rustandi; Kristen M Vallely; Olga Varlamova; M G Klein; Steven C Almo; Anne R Bresnick; David Weber
1H, 13C, 15N NMR sequence-specific resonance assignments for human apo-Mts1 (S100A4).
Journal of biomolecular NMR 2001;19(4):381-2.
2001: J C Schwartz; X Zhang; Alexander A Fedorov; Stanley G Nathenson; Steven C Almo
Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.
Nature 2001;410(6828):604-8.
2001: Alexander A Fedorov; Wuxian Shi; Gregory A Kicska; Elena V Fedorov; Peter C Tyler; Richard H Furneaux; J C Hanson; Graeme J Gainsford; John Larese; Vern L Schramm; Steven C Almo
Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
Biochemistry 2001;40(4):853-60.
2000: David A Ostrov; Wuxian Shi; Jean-Claude D Schwartz; Steven C Almo; Stanley G Nathenson
Structure of murine CTLA-4 and its role in modulating T cell responsiveness.
Science (New York, N.Y.) 2000;290(5492):816-9.
2000: A Melián; G F Watts; Abdijapar Shamshiev; Gennaro De Libero; A Clatworthy; M Vincent; Michael B Brenner; Samuel M Behar; Kayvan R Niazi; Robert L Modlin; Steven C Almo; David A Ostrov; Stanley G Nathenson; Steven A Porcelli
Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4494-504.
2000: A K Wolven; Lisa Belmont; Nicole Mahoney; Steven C Almo; David G Drubin
In vivo importance of actin nucleotide exchange catalyzed by profilin.
The Journal of cell biology 2000;150(4):895-904.
2000: J Apgar; Yiider Tseng; Elena Fedorov; M B Herwig; Steven C Almo; Denis Wirtz
Multiple-particle tracking measurements of heterogeneities in solutions of actin filaments and actin bundles.
Biophysical journal 2000;79(2):1095-106.
2000: M Sarmiento; Yoram A Puius; S W Vetter; YF Keng; Li Wu; Y Zhao; David S Lawrence; Steven C Almo; Zhong-Yin Zhang
Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry 2000;39(28):8171-9.
2000: Wuxian Shi; N R Munagala; Ching C Wang; CM Li; Peter C Tyler; Richard H Furneaux; Charles Grubmeyer; Vern L Schramm; Steven C Almo
Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry 2000;39(23):6781-90.
2000: Yoram A Puius; Elena V Fedorov; Ludwig Eichinger; Michael Schleicher; Steven C Almo
Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry 2000;39(18):5322-31.
2000: E Burke; N M Mahoney; Steven C Almo; Sailen Barik
Profilin is required for optimal actin-dependent transcription of respiratory syncytial virus genome RNA.
Journal of virology 2000;74(2):669-75.
1999: Stephen K Burley; Steven C Almo; Jeffrey B Bonanno; M Capel; Mark R Chance; T Gaasterland; D Lin; Andrej Sali; F William Studier; Subramanyam Swaminathan
Structural genomics: beyond the human genome project.
Nature genetics 1999;23(2):151-7.
1999: S Levin; Steven C Almo; Birgit H Satir
Functional diversity of the phosphoglucomutase superfamily: structural implications.
Protein engineering 1999;12(9):737-46.
1999: W Shi; CM Li; Peter C Tyler; Richard H Furneaux; Sean M Cahill; Mark E Girvin; Charles Grubmeyer; Vern L Schramm; Steven C Almo
The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
Biochemistry 1999;38(31):9872-80.
1999: W Shi; Vern L Schramm; Steven C Almo
Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-å crystal structure.
The Journal of biological chemistry 1999;274(30):21114-20.
1999: Nicole Mahoney; Denise A Rozwarski; Elena V Fedorov; Alexander A Fedorov; Steven C Almo
Profilin binds proline-rich ligands in two distinct amide backbone orientations.
Nature structural biology 1999;6(7):666-71.
1999: Alexander A Fedorov; Elena V Fedorov; F Gertler; Steven C Almo
Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function.
Nature structural biology 1999;6(7):661-5.
1999: Wuxian Shi; CM Li; Peter C Tyler; Richard H Furneaux; Charles Grubmeyer; Vern L Schramm; Steven C Almo
The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
Nature structural biology 1999;6(6):588-93.
1998: S Liu; Alexander A Fedorov; Thomas D Pollard; Eaton E Lattman; Steven C Almo; K A Magnus
Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii.
Journal of structural biology 1998;123(1):22-9.
1998: Dorit Hanein; Niels Volkmann; S Goldsmith; A M Michon; W Lehman; R Craig; David J DeRosier; Steven C Almo; P Matsudaira
An atomic model of fimbrin binding to F-actin and its implications for filament crosslinking and regulation.
Nature structural biology 1998;5(9):787-92.
1998: J Mitra; X Tang; Steven C Almo; Dennis Shields
Temperature-induced conformational changes in prosomatostatin-II: implications for processing.
The Biochemical journal 1998;334 ( Pt 1)():275-82.
1998: JC Eads; Nicole Mahoney; S Vorobiev; Anne R Bresnick; Kuo-Kuang Wen; Peter A Rubenstein; B K Haarer; Steven C Almo
Structure determination and characterization of Saccharomyces cerevisiae profilin.
Biochemistry 1998;37(32):11171-81.
1998: Rudolf Valenta; Steven C Almo; Tanja Ball; C Dolecek; Peter Steinberger; Sylvia Laffer; Petra Eibensteiner; Sabine Flicker; Susanne Vrtala; Susanne Spitzauer; Peter Valent; S Denepoux; Dietrich Kraft; Jacques Banchereau; Serge Lebecque
The immunoglobulin E-allergen interaction: a target for therapy of type I allergic diseases.
International archives of allergy and immunology 1998;116(3):167-76.
1998: Yoram A Puius; M Zou; Nancy T Ho; Chien Ho; Steven C Almo
Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp).
Biochemistry 1998;37(26):9258-65.
1998: C Mao; William J Cook; M Zhou; A A Federov; Steven C Almo; Steven E Ealick
Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry 1998;37(20):7135-46.
1998: M Degano; Steven C Almo; James C Sacchettini; Vern L Schramm
Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor.
Biochemistry 1998;37(18):6277-85.
1998: Larysa Patskovska; Alexander A Fedorov; Yury Patskovsky; Steven C Almo; Irving Listowsky
Expression, crystallization and preliminary X-ray analysis of ligand-free human glutathione S-transferase M2-2.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 3):458-60.
1998: Yoram A Puius; Nicole Mahoney; Steven C Almo
The modular structure of actin-regulatory proteins.
Current opinion in cell biology 1998;10(1):23-34.
1998: Nicole Mahoney; Steven C Almo
Crystallization and preliminary X-ray analysis of human platelet profilin complexed with an oligo proline peptide.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 1):108-10.
1997: Yoram A Puius; Y Zhao; M Sullivan; David S Lawrence; Steven C Almo; Zhong-Yin Zhang
Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13420-5.
1997: Nicole Mahoney; P A Janmey; Steven C Almo
Structure of the profilin-poly-L-proline complex involved in morphogenesis and cytoskeletal regulation.
Nature structural biology 1997;4(11):953-60.
1997: Pekka Lappalainen; Elena V Fedorov; Alexander A Fedorov; Steven C Almo; David G Drubin
Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis.
The EMBO journal 1997;16(18):5520-30.
1997: S C Goldsmith; N Pokala; W Shen; Alexander A Fedorov; P Matsudaira; Steven C Almo
The structure of an actin-crosslinking domain from human fimbrin.
Nature structural biology 1997;4(9):708-12.
1997: S C Goldsmith; N Pokala; P Matsudaira; Steven C Almo
Crystallization and preliminary crystallographic analysis of the N-terminal actin binding domain of human fimbrin.
Proteins 1997;28(3):452-3.
1997: Alexander A Fedorov; Pekka Lappalainen; Elena V Fedorov; David G Drubin; Steven C Almo
Structure determination of yeast cofilin.
Nature structural biology 1997;4(5):366-9.
1997: Alexander A Fedorov; Tanja Ball; Rudolf Valenta; Steven C Almo
X-ray crystal structures of birch pollen profilin and Phl p 2.
International archives of allergy and immunology 1997;113(1-3):109-13.
1997: Alexander A Fedorov; Tanja Ball; Nicole Mahoney; Rudolf Valenta; Steven C Almo
The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin.
Structure (London, England : 1993) 1997;5(1):33-45.
1996: Alexander A Fedorov; D Joseph-McCarthy; Elena V Fedorov; D Sirakova; I Graf; Steven C Almo
Ionic interactions in crystalline bovine pancreatic ribonuclease A.
Biochemistry 1996;35(50):15962-79.
1996: P Wiedemann; K Giehl; Steven C Almo; Alexander A Fedorov; Mark E Girvin; Peter Steinberger; M Rüdiger; M Ortner; Manfred J Sippl; C Dolecek; Dietrich Kraft; Brigitte M Jockusch; Rudolf Valenta
Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody.
The Journal of biological chemistry 1996;271(47):29915-21.
1996: D Joseph-McCarthy; Alexander A Fedorov; Steven C Almo
Comparison of experimental and computational functional group mapping of an RNase A structure: implications for computer-aided drug design.
Protein engineering 1996;9(9):773-80.
1994: Alexander A Fedorov; K A Magnus; M H Graupe; Eaton E Lattman; Thomas D Pollard; Steven C Almo
X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8636-40.
1994: Alexander A Fedorov; Thomas D Pollard; Steven C Almo
Purification, characterization and crystallization of human platelet profilin expressed in Escherichia coli.
Journal of molecular biology 1994;241(3):480-2.
1994: Steven C Almo; D L Smith; A T Danishefsky; Dagmar Ringe
The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli.
Protein engineering 1994;7(3):405-12.
1994: Steven C Almo; Thomas D Pollard; M Way; Eaton E Lattman
Purification, characterization and crystallization of Acanthamoeba profilin expressed in Escherichia coli.
Journal of molecular biology 1994;236(3):950-2.
1994: Thomas D Pollard; Steven C Almo; S Quirk; V Vinson; Eaton E Lattman
Structure of actin binding proteins: insights about function at atomic resolution.
Annual review of cell biology 1994;10():207-49.
1992: P L Howell; Steven C Almo; M R Parsons; J Hajdu; Gregory A Petsko
Structure determination of turkey egg-white lysozyme using Laue diffraction data.
Acta crystallographica. Section B, Structural science 1992;48 ( Pt 2)():200-7.
1990: Ilme Schlichting; Steven C Almo; G Rapp; K Wilson; K Petratos; A Lentfer; Alfred Wittinghofer; W Kabsch; Emil F Pai; G A Petsko
Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.
Nature 1990;345(6273):309-15.
1989: D L Smith; Steven C Almo; M D Toney; Dagmar Ringe
2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli.
Biochemistry 1989;28(20):8161-7.
1989: A Mondragón; S Subbiah; Steven C Almo; M Drottar; S C Harrison
Structure of the amino-terminal domain of phage 434 repressor at 2.0 A resolution.
Journal of molecular biology 1989;205(1):189-200.
1988: G K Farber; P Machin; Steven C Almo; Gregory A Petsko; J Hajdu
X-ray Laue diffraction from crystals of xylose isomerase.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):112-5.