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Neil Almond

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Jane L Mitchell; Meera Sethi; Erin Wigglesworth; Neil Almond; Ghazi Auda; Simon Hood; Edward T Mee; Nicola J Rose
Simian T-cell lymphotropic virus type I alters the proviral load and biodistribution of simian retrovirus type 2 in co-infected macaques, supporting advancement of immunosuppressive pathology.
Giada Mattiuzzo; Nicola J Rose; Greg J Towers; Neil Almond; Neil Berry
Upregulation of TRIM5α gene expression after live-attenuated simian immunodeficiency virus vaccination in Mauritian cynomolgus macaques, but TRIM5α genotype has no impact on virus acquisition or vaccination outcome.
Sean Clarke; Jack Alden; Neil Almond; Neil Berry; Claire Ham; Debbie Ferguson
Neuropathology of wild-type and nef-attenuated T cell tropic simian immunodeficiency virus (SIVmac32H) and macrophage tropic neurovirulent SIVmac17E-Fr in cynomolgus macaques.

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All Publications

2013: Jane L Mitchell; Meera Sethi; Erin Wigglesworth; Neil Almond; Ghazi Auda; Simon Hood; Edward T Mee; Nicola J Rose
Simian T-cell lymphotropic virus type I alters the proviral load and biodistribution of simian retrovirus type 2 in co-infected macaques, supporting advancement of immunosuppressive pathology.
The Journal of general virology 2013;94(Pt 3):623-33.
2013: Giada Mattiuzzo; Nicola J Rose; Greg J Towers; Neil Almond; Neil Berry
Upregulation of TRIM5α gene expression after live-attenuated simian immunodeficiency virus vaccination in Mauritian cynomolgus macaques, but TRIM5α genotype has no impact on virus acquisition or vaccination outcome.
The Journal of general virology 2013;94(Pt 3):606-11.
2012: Sean Clarke; Jack Alden; Neil Almond; Neil Berry; Claire Ham; Debbie Ferguson
Neuropathology of wild-type and nef-attenuated T cell tropic simian immunodeficiency virus (SIVmac32H) and macrophage tropic neurovirulent SIVmac17E-Fr in cynomolgus macaques.
Journal of neurovirology 2012;18(2):100-12.
2012: Richard Stebbings; Gerald Voss; Neil Almond; Michèle Février; Joanna Hall; Marguerite Koutsoukos; Bo Li; Clarisse Lorin; Edward Mee; Mark Page; Nicola Rose; Frédéric Tangy
Immunogenicity of a recombinant measles-HIV-1 clade B candidate vaccine.
PloS one 2012;7(11):e50397.
2012: Mark Page; Ruby Quartey-Papafio; Nicola J Rose; Richard Stebbings; E James Stott; Gerald Voss; Neil Berry; Leanne Davis; Laura Duffy; William Elsley; Deborah Ferguson; Joanna Hall; Claire Ham; Mark Hassall; Robin Hull; Bo Li; Nathalie Mathy; Edward T Mee; Neil Almond
Heterologous protection elicited by candidate monomeric recombinant HIV-1 gp120 vaccine in the absence of cross neutralising antibodies in a macaque model.
Retrovirology 2012;9():56.
2011: Jane L Mitchell; Claire K Murrell; Ghazi Auda; Neil Almond; Nicola J Rose
Early immunopathology events in simian retrovirus, type 2 infections prior to the onset of disease.
Virology 2011;413(2):161-8.
2011: Neil Berry; William Elsley; Deborah Ferguson; Claire Ham; Adrian Jenkins; Giada Mattiuzzo; Edward T Mee; Mark Page; Mark Robinson; Nicola J Rose; Deborah Smith; Neil Almond; Greg Towers; Richard Stebbings
Early potent protection against heterologous SIVsmE660 challenge following live attenuated SIV vaccination in Mauritian cynomolgus macaques.
PloS one 2011;6(8):e23092.
2010: E T Mee; Neil Berry; C Ham; A Aubertin; Jenny Lines; J Hall; Richard Stebbings; M Page; Neil Almond; Nicola J Rose
Mhc haplotype M3 is associated with early control of SHIVsbg infection in Mauritian cynomolgus macaques.
Tissue antigens 2010;76(3):223-9.
2010: Claire Ham; Priya Srinivasan; Rigmor Thorstensson; Ernst Verschoor; Zahra Fagrouche; Leonardo Sernicola; Artur Ramos; Fausto Titti; Neil Almond; Neil Berry
International multicenter study to assess a panel of reference materials for quantification of simian immunodeficiency virus RNA in plasma.
Journal of clinical microbiology 2010;48(7):2582-5.
2009: E T Mee; C K Murrell; J Watkins; Neil Almond; K Cutler; Nicola J Rose
Low rates of transmission of SRV-2 and STLV-I to juveniles in a population of Macaca fascicularis facilitate establishment of specific retrovirus-free colonies.
Journal of medical primatology 2009;38(3):160-70.
2009: Edward T Mee; Neil Berry; Claire Ham; Ulrike Sauermann; Maria T Maggiorella; Frédéric Martinon; Ernst J Verschoor; Jonathan Luke Heeney; Roger Le Grand; Fausto Titti; Neil Almond; Nicola J Rose
Mhc haplotype H6 is associated with sustained control of SIVmac251 infection in Mauritian cynomolgus macaques.
Immunogenetics 2009;61(5):327-39.
2009: Edward T Mee; Anjna Badhan; Julie A Karl; Roger W Wiseman; Keith Cutler; Leslie A Knapp; Neil Almond; David H O'Connor; Nicola J Rose
MHC haplotype frequencies in a UK breeding colony of Mauritian cynomolgus macaques mirror those found in a distinct population from the same geographic origin.
Journal of medical primatology 2009;38(1):1-14.
2008: E T Mee; C K Murrell; U Sauermann; R C Wilkinson; K Cutler; D North; A Heath; Kaetan Ladhani; Neil Almond; Nicola J Rose
The Mhc class II DRB genotype of Macaca fascicularis does not influence infection by simian retrovirus type 2.
Tissue antigens 2008;72(4):369-78.
2008: Neil Berry; Richard Stebbings; Deborah Ferguson; Claire Ham; Jack Alden; Stuart Brown; Adrian Jenkins; Jenny Lines; Laura Duffy; Leanne Davis; William Elsley; Mark Page; Robin Hull; Jim Stott; Neil Almond
Resistance to superinfection by a vigorously replicating, uncloned stock of simian immunodeficiency virus (SIVmac251) stimulates replication of a live attenuated virus vaccine (SIVmacC8).
The Journal of general virology 2008;89(Pt 9):2240-51.
2007: Deborah Ferguson; Alison M Wade-Evans; William Elsley; Rebecca Sangster; Peter Silvera; S MacManus; Gail Davis; Terry Corcoran; Neil Berry; Stuart Brown; Adrian Jenkins; Jenny Cowie; M Sethi; Robin Hull; Richard Stebbings; Jenny Lines; S Norley; E Jim Stott; Neil Almond
Preparation and characterization of new challenge stocks of SIVmac32H J5 following rapid serial passage of virus in vivo.
Journal of medical primatology 2007;36(3):131-42.
2007: Neil Berry; Richard Stebbings; Stuart Brown; P Christian; Rigmor Thorstensson; R K Ahmed; L Davis; Deborah Ferguson; N D'Arcy; William Elsley; Robin Hull; Jenny Lines; Alison M Wade-Evans; Jim Stott; Neil Almond
Immunological responses and viral modulatory effects of vaccination with recombinant modified vaccinia virus Ankara (rMVA) expressing structural and regulatory transgenes of simian immunodeficiency virus (SIVmac32H/J5M).
Journal of medical primatology 2007;36(2):80-94.
2007: Mark Page; Agatha Ojugo; Nesrina Imami; Gareth Hardy; Frances Gotch; Neil Almond
Specificity of anti-human leukocyte antigen antibody responses after immunization with Remune, an inactivated HIV-1 vaccine.
AIDS (London, England) 2007;21(3):375-7.
2005: Richard Stebbings; Neil Berry; Herman Waldmann; Pru Bird; Geoff Hale; Jim Stott; David North; Robin Hull; Joanna Hall; Jenny Lines; Stuart Brown; Nikki D'Arcy; Leanne Davis; William Elsley; Cherry Edwards; Deborah Ferguson; Jane Allen; Neil Almond
CD8+ lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus.
Journal of virology 2005;79(19):12264-72.
2005: Neil Berry; Adrian Jenkins; Javier Martin; Clare Davis; D Wood; Geoffrey Schild; Margareta Bottiger; Harvey Holmes; Philip Minor; Neil Almond
Mitochondrial DNA and retroviral RNA analyses of archival oral polio vaccine (OPV CHAT) materials: evidence of macaque nuclear sequences confirms substrate identity.
Vaccine 2005;23(14):1639-48.
2004: Richard Stebbings; Neil Berry; Jim Stott; Robin Hull; Kenneth Barry Walker; Jenny Lines; William Elsley; Stuart Brown; Alison M Wade-Evans; Gail Davis; Jenny Cowie; Meera Sethi; Neil Almond
Vaccination with live attenuated simian immunodeficiency virus for 21 days protects against superinfection.
Virology 2004;330(1):249-60.
2004: Sally A Sharpe; Alethea Cope; Stuart Dowall; Neil Berry; Claire Ham; Jonathan Luke Heeney; Donna Hopkins; Linda Easterbrook; Mike Dennis; Neil Almond; Martin Cranage
Macaques infected long-term with attenuated simian immunodeficiency virus (SIVmac) remain resistant to wild-type challenge, despite declining cytotoxic T lymphocyte responses to an immunodominant epitope.
The Journal of general virology 2004;85(Pt 9):2591-602.
2004: N Leuchte; N Berry; B Köhler; Neil Almond; R LeGrand; Rigmor Thorstensson; Fausto Titti; Ulrike Sauermann
MhcDRB-sequences from cynomolgus macaques (Macaca fascicularis) of different origin.
Tissue antigens 2004;63(6):529-37.
2003: Elizabeth Padua; Adrian Jenkins; Stuart Brown; Janet Bootman; Maria Teresa Paixao; Neil Almond; Neil Berry
Natural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal.
The Journal of general virology 2003;84(Pt 5):1287-99.
2003: S Clarke; Neil Almond; Neil Berry
Simian immunodeficiency virus Nef gene regulates the production of 2-LTR circles in vivo.
Virology 2003;306(1):100-8.
2002: Richard Stebbings; Neil Almond; E Jim Stott; Neil Berry; Alison M Wade-Evans; Robin Hull; Jenny Lines; Peter Silvera; Rebecca Sangster; Terry Corcoran; Jane Rose; Kenneth Barry Walker
Mechanisms of protection induced by attenuated simian immunodeficiency virus.
Virology 2002;296(2):338-53.
2001: Alison M Wade-Evans; Jim Stott; T Hanke; Richard Stebbings; Neil Berry; Jenny Lines; Rebecca Sangster; Peter Silvera; Kenneth Barry Walker; S MacManus; Gail Davis; Jenny Cowie; C Arnold; Robin Hull; Neil Almond
Specific proliferative T cell responses and antibodies elicited by vaccination with simian immunodeficiency virus Nef do not confer protection against virus challenge.
AIDS research and human retroviruses 2001;17(16):1517-26.
2001: C Cantó-Nogués; S Jones; Rebecca Sangster; Peter Silvera; Robin Hull; R Cook; G Hall; Kenneth Barry Walker; E Jim Stott; D Hockley; Neil Almond
In situ hybridization and immunolabelling study of the early replication of simian immunodeficiency virus (SIVmacJ5) in vivo.
The Journal of general virology 2001;82(Pt 9):2225-34.
2001: Jonathan Weber; Andrew J Nunn; T O'Connor; D Jeffries; Valerie S Kitchen; Sheena McCormack; J Stott; Neil Almond; A Stone; Janet Darbyshire
'Chemical condoms' for the prevention of HIV infection: evaluation of novel agents against SHIV(89.6PD) in vitro and in vivo.
AIDS (London, England) 2001;15(12):1563-8.
2001: Peter Ten Haaft; Neil Almond; Gunnel Biberfeld; Aurelio Aurelio Cafaro; Martin Cranage; Barbara Ensoli; Gerhard Hunsmann; Natasha Polyanskaya; Christiane Stahl-Hennig; R Thortensson; Fausto Titti; Jonathan Luke Heeney
Comparison of early plasma RNA loads in different macaque species and the impact of different routes of exposure on SIV/SHIV infection.
Journal of medical primatology 2001;30(4):207-14.
2001: C Cantó-Nogués; D Hockley; C Grief; S Ranjbar; J Bootman; Neil Almond; I Herrera
Ultrastructural localization of the RNA of immunodeficiency viruses using electron microscopy in situ hybridization and in vitroinfected lymphocytes.
Micron (Oxford, England : 1993) 2001;32(6):579-89.
2001: Neil Berry; Clare Davis; Adrian Jenkins; D Wood; P Minor; Geoffrey Schild; M Bottiger; Harvey Holmes; Neil Almond
Vaccine safety. Analysis of oral polio vaccine CHAT stocks.
Nature 2001;410(6832):1046-7.
2001: Peter Silvera; Alison M Wade-Evans; Erling Rud; Robin Hull; K Silvera; Rebecca Sangster; Neil Almond; Jim Stott
Mechanisms of protection induced by live attenuated simian immunodeficiency virus: III. Viral interference and the role of CD8+ T-cells and beta-chemokines in the inhibition of virus infection of PBMCs in vitro.
Journal of medical primatology 2001;30(1):1-13.
2000: S Ranjbar; U Bhattacharya; J Oram; E Jim Stott; Neil Almond
Construction of infectious SIV/HIV-2 chimeras.
AIDS (London, England) 2000;14(16):2479-84.
2000: J Mills; R Desrosiers; Erling Rud; Neil Almond
Live attenuated HIV vaccines: a proposal for further research and development.
AIDS research and human retroviruses 2000;16(15):1453-61.
1999: Neil Almond; Adrian Jenkins; S Jones; C Arnold; Peter Silvera; K Kent; K H Mills; E Jim Stott
The appearance of escape variants in vivo does not account for the failure of recombinant envelope vaccines to protect against simian immunodeficiency virus.
The Journal of general virology 1999;80 ( Pt 9)():2375-82.
1999: C Arnold; Adrian Jenkins; Neil Almond; E Jim Stott; K A Kent
Monoclonal antibodies recognize at least five epitopes on the SIV Nef protein and identify an in vitro-induced mutation.
AIDS research and human retroviruses 1999;15(12):1087-97.
1999: Neil Almond; Jim Stott
Live attenuated SIV--a model of a vaccine for AIDS.
Immunology letters 1999;66(1-3):167-70.
1998: Jim Stott; S L Hu; Neil Almond
Candidate vaccines protect macaques against primate immunodeficiency viruses.
AIDS research and human retroviruses 1998;14 Suppl 3():S265-70.
1998: Richard Stebbings; Jim Stott; Neil Almond; Robin Hull; Jenny Lines; Peter Silvera; Rebecca Sangster; Terry Corcoran; Jane Rose; S Cobbold; F Gotch; A McMichael; Kenneth Barry Walker
Mechanisms of protection induced by attenuated simian immunodeficiency virus. II. Lymphocyte depletion does not abrogate protection.
AIDS research and human retroviruses 1998;14(13):1187-98.
1998: Petra Mooij; M van der Kolk; Willy M J M Bogers; Peter Ten Haaft; Peter H van der Meide; Neil Almond; J Stott; M Deschamps; D Labbe; P Momin; Gerald Voss; Paul von Hoegen; Claudine Bruck; Jonathan Luke Heeney
A clinically relevant HIV-1 subunit vaccine protects rhesus macaques from in vivo passaged simian-human immunodeficiency virus infection.
AIDS (London, England) 1998;12(5):F15-22.
1998: E Jim Stott; Neil Almond; K Kent; Kenneth Barry Walker; Robin Hull; Jane Rose; Peter Silvera; Rebecca Sangster; Terry Corcoran; Jenny Lines; K Silvera; Paul A Luciw; M Murphy-Corb; P Momin; Claudine Bruck
Evaluation of a candidate human immunodeficiency virus type 1 (HIV-1) vaccine in macaques: effect of vaccination with HIV-1 gp120 on subsequent challenge with heterologous simian immunodeficiency virus-HIV-1 chimeric virus.
The Journal of general virology 1998;79 ( Pt 3)():423-32.
1998: Neil Almond; Jonathan Luke Heeney
AIDS vaccine development in primate models.
AIDS (London, England) 1998;12 Suppl A():S133-40.
1997: Willy M J M Bogers; Rob Dubbes; Peter Ten Haaft; Henk Niphuis; C Cheng-Mayer; Christiane Stahl-Hennig; Gerhard Hunsmann; T Kuwata; M Hayami; S Jones; S Ranjbar; Neil Almond; J Stott; Brigitte Rosenwirth; Jonathan Luke Heeney
Comparison of in vitro and in vivo infectivity of different clade B HIV-1 envelope chimeric simian/human immunodeficiency viruses in Macaca mulatta.
Virology 1997;236(1):110-7.
1997: Neil Almond; Jane Rose; Rebecca Sangster; Peter Silvera; Richard Stebbings; Kenneth Barry Walker; E Jim Stott
Mechanisms of protection induced by attenuated simian immunodeficiency virus. I. Protection cannot be transferred with immune serum.
The Journal of general virology 1997;78 ( Pt 8)():1919-22.
1997: Xiao-Ning Xu; Gavin Screaton; F M Gotch; Tao Dong; R Tan; Neil Almond; Kenneth Barry Walker; Richard Stebbings; K Kent; S Nagata; Jim Stott; Andrew J McMichael
Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells.
The Journal of experimental medicine 1997;186(1):7-16.
1997: S Ranjbar; S Jones; E Jim Stott; Neil Almond
The construction and evaluation of SIV/HIV chimeras that express the envelope of European HIV type 1 isolates.
AIDS research and human retroviruses 1997;13(9):797-800.
1997: R J Stabbings; Jenny Lines; Neil Almond; E Jim Stott; Kenneth Barry Walker
Cytokine profiling of simian immunodeficiency virus infection of cynomologus macaques. Pathogenic SIVmac251 pJ5C versus non-pathogenic attenuated SIVmac251 pC8C reveals divergence.
Biochemical Society transactions 1997;25(2):285S.
1997: Jenny Lines; Kenneth Barry Walker; Neil Almond; E Jim Stott; Richard Stebbings
Comparison of peripheral blood phenotype in pathogenic and attenuated SIV infection.
Biochemical Society transactions 1997;25(2):284S.
1997: Neil Almond; Terry Corcoran; Robin Hull; Kenneth Barry Walker; Jane Rose; Rebecca Sangster; K Silvera; Peter Silvera; Martin Cranage; Erling Rud; E Jim Stott
Mechanisms of protection induced by attenuated simian immunodeficiency virus. IV. Protection against challenge with virus grown in autologous simian cells.
Journal of medical primatology 1997;26(1-2):34-43.
1995: A Slade; S Jones; Adrian Jenkins; J Bootman; A Heath; P Kitchin; Neil Almond
Similar patterns of simian immunodeficiency virus env sequences are found in the blood and lymphoid tissues of chronically infected macaques.
AIDS research and human retroviruses 1995;11(12):1509-11.
1995: A Gallimore; Martin Cranage; Nicola Cook; Neil Almond; J Bootman; Erling Rud; Peter Silvera; M Dennis; Terry Corcoran; Jim Stott
Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques.
Nature medicine 1995;1(11):1167-73.
1995: S Ranjbar; A Slade; Adrian Jenkins; A Heath; P Kitchin; Neil Almond; S Osmanov; H Holmes
Molecular characterization of an HIV type 1 isolate from Burundi.
AIDS research and human retroviruses 1995;11(8):981-4.
1995: Neil Almond; K Kent; Martin Cranage; Erling Rud; B Clarke; E Jim Stott
Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells.
Lancet 1995;345(8961):1342-4.
1995: Jim Stott; Neil Almond
Assessing animal models of AIDS.
Nature medicine 1995;1(4):295-7.
1995: W L Chan; A Rodgers; C Grief; Neil Almond; S Ellis; B Flanagan; Peter Silvera; J Bootman; Jim Stott; K Kent
Immunization with class I human histocompatibility leukocyte antigen can protect macaques against challenge infection with SIVmac-32H.
AIDS (London, England) 1995;9(3):223-8.
1995: Jane Rose; Peter Silvera; B Flanagan; P Kitchin; Neil Almond
The development of PCR based assays for the detection and differentiation of simian immunodeficiency virus in vivo.
Journal of virological methods 1995;51(2-3):229-39.
1994: Z Szotyori; Neil Almond; P Kitchin
Complex splicing of simian immunodeficiency virus (mac 251-32H) rev gene transcript from infected macaques.
AIDS research and human retroviruses 1994;10(3):315-8.
1994: R J Sugrue; Neil Almond; P Kitchin; S M Richardson; A F Wilderspin
Purification of crystallizable recombinant SIVmac251-32H proteinase.
Protein expression and purification 1994;5(1):76-83.
1993: Neil Almond; Adrian Jenkins; Alan B Heath; P Kitchin
Sequence variation in the env gene of simian immunodeficiency virus recovered from immunized macaques is predominantly in the V1 region.
The Journal of general virology 1993;74 ( Pt 5)():865-71.
1993: A Slade; S Jones; Neil Almond; P Kitchin
Simian immunodeficiency virus (mac 251-32H) transmembrane protein sequence remains conserved throughout the course of infection in macaques.
AIDS research and human retroviruses 1993;9(2):133-9.
1992: Neil Almond; Adrian Jenkins; Alan B Heath; L F Taffs; P Kitchin
The genetic evolution of the envelope gene of simian immunodeficiency virus in cynomolgus macaques infected with a complex virus pool.
Virology 1992;191(2):996-1002.
1992: Neil Almond; S Jones; Alan B Heath; P A Kitchin
The assessment of nucleotide sequence diversity by the polymerase chain reaction is highly reproducible.
Journal of virological methods 1992;40(1):37-44.
1992: Neil Almond; Adrian Jenkins; A Slade; A Heath; Martin Cranage; P Kitchin
Population sequence analysis of a simian immunodeficiency virus (32H reisolate of SIVmac251): a virus stock used for international vaccine studies.
AIDS research and human retroviruses 1992;8(1):77-88.
1990: Neil Almond; M Page; K Mills; Adrian Jenkins; C Ling; Robin Thorpe; P Kitchin; M Williams
The production and purification of PCR-derived recombinant simian immunodeficiency virus p27 gag protein; its use in detecting serological and T-cell responses in macaques.
Journal of virological methods 1990;28(3):305-19.
1990: P A Kitchin; Neil Almond; Z Szotyori; C E Fromholc; L McAlpine; Peter Silvera; E Jim Stott; Martin Cranage; A Baskerville; G Schild
The use of the polymerase chain reaction for the detection of Simian immunodeficiency virus in experimentally infected macaques.
Journal of virological methods 1990;28(1):85-99.
1990: P A Kitchin; Z Szotyori; C Fromholc; Neil Almond
Avoidance of PCR false positives [corrected].
Nature 1990;344(6263):201.
1989: Martin Cranage; Neil Almond; Adrian Jenkins; P A Kitchin
Transmembrane protein of SIV.
Nature 1989;342(6248):349.