Pieter Cullis

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Cressman Sonya; Dobson Ian; Lee Justin B; Tam Yuen Yi C; Cullis Pieter R
Synthesis of a labeled RGD-lipid, its incorporation into liposomal nanoparticles, and their trafficking in cultured endothelial cells.
Chikh Ghania; de Jong Susan D; Sekirov Laura; Raney Sameersingh G; Kazem Mikameh; Wilson Kaley D; Cullis Pieter R; Dutz Jan P; Tam Ying K
Synthetic methylated CpG ODNs are potent in vivo adjuvants when delivered in liposomal nanoparticles.
Wilson Kaley D; de Jong Susan D; Kazem Mikameh; Lall Ryan; Hope Michael J; Cullis Pieter R; Tam Ying K
The combination of stabilized plasmid lipid particles and lipid nanoparticle encapsulated CpG containing oligodeoxynucleotides as a systemic genetic vaccine.

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All Publications

2009: Cressman Sonya; Dobson Ian; Lee Justin B; Tam Yuen Yi C; Cullis Pieter R
Synthesis of a labeled RGD-lipid, its incorporation into liposomal nanoparticles, and their trafficking in cultured endothelial cells.
Bioconjugate chemistry 2009;20(7):1404-11.
2009: Chikh Ghania; de Jong Susan D; Sekirov Laura; Raney Sameersingh G; Kazem Mikameh; Wilson Kaley D; Cullis Pieter R; Dutz Jan P; Tam Ying K
Synthetic methylated CpG ODNs are potent in vivo adjuvants when delivered in liposomal nanoparticles.
International immunology 2009;21(7):757-67.
2009: Wilson Kaley D; de Jong Susan D; Kazem Mikameh; Lall Ryan; Hope Michael J; Cullis Pieter R; Tam Ying K
The combination of stabilized plasmid lipid particles and lipid nanoparticle encapsulated CpG containing oligodeoxynucleotides as a systemic genetic vaccine.
The journal of gene medicine 2009;11(1):14-25.
2008: Raney Sameersingh G; Wilson Kaley D; Sekirov Laura; Chikh Ghania; de Jong Susan D; Cullis Pieter R; Tam Ying K
The effect of circulation lifetime and drug-to-lipid ratio of intravenously administered lipid nanoparticles on the biodistribution and immunostimulatory activity of encapsulated CpG-ODN.
Journal of drug targeting 2008;16(7):564-77.
2008: Sun Ying; Cressman Sonya; Fang Ning; Cullis Pieter R; Chen David D Y
Capillary electrophoresis frontal analysis for characterization of alphavbeta3 integrin binding interactions.
Analytical chemistry 2008;80(9):3105-11.
2008: Fenske David B; Cullis Pieter R
Liposomal nanomedicines.
Expert opinion on drug delivery 2008;5(1):25-44.
2008: Johnston Michael J W; Edwards Katarina; Karlsson Goran; Cullis Pieter R
Influence of drug-to-lipid ratio on drug release properties and liposome integrity in liposomal doxorubicin formulations.
Journal of liposome research 2008;18(2):145-57.
2008: Fenske David B; Chonn Arcadio; Cullis Pieter R
Liposomal nanomedicines: an emerging field.
Toxicologic pathology 2008;36(1):21-9.
2007: Wilson Kaley D; Raney Sameersingh G; Sekirov Laura; Chikh Ghania; deJong Susan D; Cullis Pieter R; Tam Ying K
Effects of intravenous and subcutaneous administration on the pharmacokinetics, biodistribution, cellular uptake and immunostimulatory activity of CpG ODN encapsulated in liposomal nanoparticles.
International immunopharmacology 2007;7(8):1064-75.
2007: de Jong Susan; Chikh Ghania; Sekirov Laura; Raney Sam; Semple Sean; Klimuk Sandra; Yuan Ning; Hope Micheal; Cullis Pieter; Tam Ying
Encapsulation in liposomal nanoparticles enhances the immunostimulatory, adjuvant and anti-tumor activity of subcutaneously administered CpG ODN.
Cancer immunology, immunotherapy : CII 2007;56(8):1251-64.
2007: de Jonge Jørgen; Leenhouts Johanna M; Holtrop Marijke; Schoen Pieter; Scherrer Peter; Cullis Pieter R; Wilschut Jan; Huckriede Anke
Cellular gene transfer mediated by influenza virosomes with encapsulated plasmid DNA.
The Biochemical journal 2007;405(1):41-9.
2007: Johnston Michael J W; Semple Sean C; Klimuk Sandy K; Ansell Steve; Maurer Norbert; Cullis Pieter R
Characterization of the drug retention and pharmacokinetic properties of liposomal nanoparticles containing dihydrosphingomyelin.
Biochimica et biophysica acta 2007;1768(5):1121-7.
2006: Johnston Michael J W; Semple Sean C; Klimuk Sandra K; Edwards Katarina; Eisenhardt Merete L; Leng Esther C; Karlsson Göran; Yanko Daniel; Cullis Pieter R
Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations.
Biochimica et biophysica acta 2006;1758(1):55-64.
2006: Zhigaltsev Igor V; Maurer Norbert; Edwards Katarina; Karlsson Göran; Cullis Pieter R
Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention.
Journal of controlled release : official journal of the Controlled Release Society 2006;110(2):378-86.
2005: Sandhu Ammen P; Lam Angela M I; Fenske David B; Palmer Lorne R; Johnston Michael; Cullis Pieter R
Calcium enhances the transfection potency of stabilized plasmid-lipid particles.
Analytical biochemistry 2005;341(1):156-64.
2005: Ambegia E; Ansell S; Cullis P; Heyes J; Palmer L; MacLachlan I
Stabilized plasmid-lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression.
Biochimica et biophysica acta 2005;1669(2):155-63.
2005: Zhigaltsev Igor V; Maurer Norbert; Akhong Quet-Fah; Leone Robert; Leng Esther; Wang Jinfang; Semple Sean C; Cullis Pieter R
Liposome-encapsulated vincristine, vinblastine and vinorelbine: a comparative study of drug loading and retention.
Journal of controlled release : official journal of the Controlled Release Society 2005;104(1):103-11.
2005: Semple Sean C; Leone Robert; Wang Jinfang; Leng Esther C; Klimuk Sandra K; Eisenhardt Merete L; Yuan Zuan-Ning; Edwards Katarina; Maurer Norbert; Hope Michael J; Cullis Pieter R; Ahkong Quet-Fah
Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity.
Journal of pharmaceutical sciences 2005;94(5):1024-38.
2005: Finn Jonathan; MacLachlan Ian; Cullis Pieter
Factors limiting autogene-based cytoplasmic expression systems.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(6):608-10.
2005: MacLachlan Ian; Cullis Pieter
"Diffusible-PEG-lipid stabilized plasmid lipid particles".
Advances in genetics 2005;53():157-88.
2005: Finn Jonathan D; Wong Tabitha; Cullis Pieter R
Investigation of factors responsible for cell line cytoplasmic expression differences.
BMC molecular biology 2005;6(1):11.
2005: Abraham Sheela A; Waterhouse Dawn N; Mayer Lawrence D; Cullis Pieter R; Madden Thomas D; Bally Marcel B
The liposomal formulation of doxorubicin.
Methods in enzymology 2005;391():71-97.
2005: Waterhouse Dawn N; Madden Thomas D; Cullis Pieter R; Bally Marcel B; Mayer Lawrence D; Webb Murray S
Preparation, characterization, and biological analysis of liposomal formulations of vincristine.
Methods in enzymology 2005;391():40-57.
2005: Fenske David B; Cullis Pieter R
Entrapment of small molecules and nucleic acid-based drugs in liposomes.
Methods in enzymology 2005;391():7-40.
2004: Chen Tao; McIntosh Deirdre; He Yuehua; Kim Jungsoo; Tirrell David A; Scherrer Peter; Fenske David B; Sandhu Ammen P; Cullis Pieter R
Alkylated derivatives of poly(ethylacrylic acid) can be inserted into preformed liposomes and trigger pH-dependent intracellular delivery of liposomal contents.
Molecular membrane biology 2004;21(6):385-93.
2004: Allen Theresa M; Cullis Pieter R
Drug delivery systems: entering the mainstream.
Science (New York, N.Y.) 2004;303(5665):1818-22.
2004: Finn J; Lee A C H; MacLachlan I; Cullis P
An enhanced autogene-based dual-promoter cytoplasmic expression system yields increased gene expression.
Gene therapy 2004;11(3):276-83.
2004: Chen Tao; Palmer Lorne R; Fenske David B; Lam Angela M I; Wong Kim F; Cullis Pieter R
Distal cationic poly(ethylene glycol) lipid conjugates in large unilamellar vesicles prepared by extrusion enhance liposomal cellular uptake.
Journal of liposome research 2004;14(3-4):155-73.
2004: Hafez Ismail M; Cullis Pieter R
Tunable pH-sensitive liposomes.
Methods in enzymology 2004;387():113-34.
2003: Palmer Lorne R; Chen Tao; Lam Angela M I; Fenske David B; Wong Kim F; MacLachlan Ian; Cullis Pieter R
Transfection properties of stabilized plasmid-lipid particles containing cationic PEG lipids.
Biochimica et biophysica acta 2003;1611(1-2):204-16.
2002: Zhigaltsev Igor V; Maurer Norbert; Wong Kim F; Cullis Pieter R
Triggered release of doxorubicin following mixing of cationic and anionic liposomes.
Biochimica et biophysica acta 2002;1565(1):129-35.
2002: Gaucheron Jérôme; Wong Tabitha; Wong Kim F; Maurer Norbert; Cullis Pieter R
Synthesis and properties of novel tetraalkyl cationic lipids.
Bioconjugate chemistry 2002;13(3):671-5.
2002: Cullis Pieter R
Stabilized plasmid-lipid particles for systemic gene therapy.
Cellular & molecular biology letters 2002;7(2):226.
2002: Fenske David B; MacLachlan Ian; Cullis Pieter R
Stabilized plasmid-lipid particles: a systemic gene therapy vector.
Methods in enzymology 2002;346():36-71.
2001: Maurer N; Fenske D B; Cullis P R
Developments in liposomal drug delivery systems.
Expert opinion on biological therapy 2001;1(6):923-47.
2001: Hafez I M; Maurer N; Cullis P R
On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids.
Gene therapy 2001;8(15):1188-96.
2001: Fenske D B; Palmer L R; Chen T; Wong K F; Cullis P R
Cationic poly(ethyleneglycol) lipids incorporated into pre-formed vesicles enhance binding and uptake to BHK cells.
Biochimica et biophysica acta 2001;1512(2):259-72.
2001: Maurer N; Wong K F; Stark H; Louie L; McIntosh D; Wong T; Scherrer P; Semple S C; Cullis P R
Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes.
Biophysical journal 2001;80(5):2310-26.
2001: Fenske D B; MacLachlan I; Cullis P R
Long-circulating vectors for the systemic delivery of genes.
Current opinion in molecular therapeutics 2001;3(2):153-8.
2001: Hafez I M; Cullis P R
Roles of lipid polymorphism in intracellular delivery.
Advanced drug delivery reviews 2001;47(2-3):139-48.
2001: Semple S C; Klimuk S K; Harasym T O; Dos Santos N; Ansell S M; Wong K F; Maurer N; Stark H; Cullis P R; Hope M J; Scherrer P
Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures.
Biochimica et biophysica acta 2001;1510(1-2):152-66.
2000: Tam P; Monck M; Lee D; Ludkovski O; Leng E C; Clow K; Stark H; Scherrer P; Graham R W; Cullis P R
Stabilized plasmid-lipid particles for systemic gene therapy.
Gene therapy 2000;7(21):1867-74.
2000: Oja C; Tardi P; Schutze-Redelmeier M; Cullis P R
Doxorubicin entrapped within liposome-associated antigens results in a selective inhibition of the antibody response to the linked antigen.
Biochimica et biophysica acta 2000;1468(1-2):31-40.
2000: Hafez I M; Ansell S; Cullis P R
Tunable pH-sensitive liposomes composed of mixtures of cationic and anionic lipids.
Biophysical journal 2000;79(3):1438-46.
2000: Chen T; Wong K F; Fenske D B; Palmer L R; Cullis P R
Fluorescent-labeled poly(ethylene glycol) lipid conjugates with distal cationic headgroups.
Bioconjugate chemistry 2000;11(3):433-7.
2000: Lam A M; Cullis P R
Calcium enhances the transfection potency of plasmid DNA-cationic liposome complexes.
Biochimica et biophysica acta 2000;1463(2):279-90.
2000: Hafez I M; Cullis P R
Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior.
Biochimica et biophysica acta 2000;1463(1):107-14.
2000: Monck M A; Mori A; Lee D; Tam P; Wheeler J J; Cullis P R; Scherrer P
Stabilized plasmid-lipid particles: pharmacokinetics and plasmid delivery to distal tumors following intravenous injection.
Journal of drug targeting 2000;7(6):439-52.
2000: Saravolac E G; Ludkovski O; Skirrow R; Ossanlou M; Zhang Y P; Giesbrecht C; Thompson J; Thomas S; Stark H; Cullis P R; Scherrer P
Encapsulation of plasmid DNA in stabilized plasmid-lipid particles composed of different cationic lipid concentration for optimal transfection activity.
Journal of drug targeting 2000;7(6):423-37.
1999: Zhang Y P; Sekirov L; Saravolac E G; Wheeler J J; Tardi P; Clow K; Leng E; Sun R; Cullis P R; Scherrer P
Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties.
Gene therapy 1999;6(8):1438-47.
1999: Mok K W; Lam A M; Cullis P R
Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties.
Biochimica et biophysica acta 1999;1419(2):137-50.
1999: Schoen P; Chonn A; Cullis P R; Wilschut J; Scherrer P
Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles.
Gene therapy 1999;6(5):823-32.
1999: MacLachlan I; Cullis P; Graham R W
Progress towards a synthetic virus for systemic gene therapy.
Current opinion in molecular therapeutics 1999;1(2):252-9.
1999: Wheeler J J; Palmer L; Ossanlou M; MacLachlan I; Graham R W; Zhang Y P; Hope M J; Scherrer P; Cullis P R
Stabilized plasmid-lipid particles: construction and characterization.
Gene therapy 1999;6(2):271-81.
1999: Maurer N; Mori A; Palmer L; Monck M A; Mok K W; Mui B; Akhong Q F; Cullis P R
Lipid-based systems for the intracellular delivery of genetic drugs.
Molecular membrane biology 1999;16(1):129-40.
1999: Maurer-Spurej E; Wong K F; Maurer N; Fenske D B; Cullis P R
Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients.
Biochimica et biophysica acta 1999;1416(1-2):1-10.
1998: Cheung B C; Sun T H; Leenhouts J M; Cullis P R
Loading of doxorubicin into liposomes by forming Mn2+-drug complexes.
Biochimica et biophysica acta 1998;1414(1-2):205-16.
1998: Fenske D B; Wong K F; Maurer E; Maurer N; Leenhouts J M; Boman N; Amankwa L; Cullis P R
Ionophore-mediated uptake of ciprofloxacin and vincristine into large unilamellar vesicles exhibiting transmembrane ion gradients.
Biochimica et biophysica acta 1998;1414(1-2):188-204.
1998: Maurer N; Wong K F; Hope M J; Cullis P R
Anomalous solubility behavior of the antibiotic ciprofloxacin encapsulated in liposomes: a 1H-NMR study.
Biochimica et biophysica acta 1998;1374(1-2):9-20.
1997: Tardi P G; Swartz E N; Harasym T O; Cullis P R; Bally M B
An immune response to ovalbumin covalently coupled to liposomes is prevented when the liposomes used contain doxorubicin.
Journal of immunological methods 1997;210(2):137-48.
1997: Mok K W; Cullis P R
Structural and fusogenic properties of cationic liposomes in the presence of plasmid DNA.
Biophysical journal 1997;73(5):2534-45.
1997: Cullis P R; Hope M J; Bally M B; Madden T D; Mayer L D; Fenske D B
Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles.
Biochimica et biophysica acta 1997;1331(2):187-211.
1997: Bailey A L; Monck M A; Cullis P R
pH-induced destabilization of lipid bilayers by a lipopeptide derived from influenza hemagglutinin.
Biochimica et biophysica acta 1997;1324(2):232-44.
1997: Parr M J; Masin D; Cullis P R; Bally M B
Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis lung carcinoma: the lack of beneficial effects by coating liposomes with poly(ethylene glycol).
The Journal of pharmacology and experimental therapeutics 1997;280(3):1319-27.
1997: Bailey A L; Cullis P R
Membrane fusion with cationic liposomes: effects of target membrane lipid composition.
Biochemistry 1997;36(7):1628-34.
1997: Harasym T O; Cullis P R; Bally M B
Intratumor distribution of doxorubicin following i.v. administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes.
Cancer chemotherapy and pharmacology 1997;40(4):309-17.
1996: Oja C D; Semple S C; Chonn A; Cullis P R
Influence of dose on liposome clearance: critical role of blood proteins.
Biochimica et biophysica acta 1996;1281(1):31-7.
1996: Holland J W; Hui C; Cullis P R; Madden T D
Poly(ethylene glycol)--lipid conjugates regulate the calcium-induced fusion of liposomes composed of phosphatidylethanolamine and phosphatidylserine.
Biochemistry 1996;35(8):2618-24.
1996: Holland J W; Cullis P R; Madden T D
Poly(ethylene glycol)-lipid conjugates promote bilayer formation in mixtures of non-bilayer-forming lipids.
Biochemistry 1996;35(8):2610-7.
1996: Semple S C; Chonn A; Cullis P R
Influence of cholesterol on the association of plasma proteins with liposomes.
Biochemistry 1996;35(8):2521-5.
1996: Tardi P G; Boman N L; Cullis P R
Liposomal doxorubicin.
Journal of drug targeting 1996;4(3):129-40.
1996: Boman N L; Tron V A; Bally M B; Cullis P R
Vincristine-induced dermal toxicity is significantly reduced when the drug is given in liposomes.
Cancer chemotherapy and pharmacology 1996;37(4):351-5.
1995: Longman S A; Tardi P G; Parr M J; Choi L; Cullis P R; Bally M B
Accumulation of protein-coated liposomes in an extravascular site: influence of increasing carrier circulation lifetimes.
The Journal of pharmacology and experimental therapeutics 1995;275(3):1177-84.
1995: Chonn A; Semple S C; Cullis P R
Beta 2 glycoprotein I is a major protein associated with very rapidly cleared liposomes in vivo, suggesting a significant role in the immune clearance of "non-self" particles.
The Journal of biological chemistry 1995;270(43):25845-9.
1995: Mui B L; Döbereiner H G; Madden T D; Cullis P R
Influence of transbilayer area asymmetry on the morphology of large unilamellar vesicles.
Biophysical journal 1995;69(3):930-41.
1995: Harasym T O; Tardi P; Longman S A; Ansell S M; Bally M B; Cullis P R; Choi L S
Poly(ethylene glycol)-modified phospholipids prevent aggregation during covalent conjugation of proteins to liposomes.
Bioconjugate chemistry 1995;6(2):187-94.
1995: Longman S A; Cullis P R; Choi L; de Jong G; Bally M B
A two-step targeting approach for delivery of doxorubicin-loaded liposomes to tumour cells in vivo.
Cancer chemotherapy and pharmacology 1995;36(2):91-101.
1994: Parr M J; Ansell S M; Choi L S; Cullis P R
Factors influencing the retention and chemical stability of poly(ethylene glycol)-lipid conjugates incorporated into large unilamellar vesicles.
Biochimica et biophysica acta 1994;1195(1):21-30.
1994: Bailey A L; Cullis P R
Modulation of membrane fusion by asymmetric transbilayer distributions of amino lipids.
Biochemistry 1994;33(42):12573-80.
1994: Chakrabarti A C; Clark-Lewis I; Cullis P R
Influence of charge, charge distribution, and hydrophobicity on the transport of short model peptides into liposomes in response to transmembrane pH gradients.
Biochemistry 1994;33(28):8479-85.
1994: Lewis R N; McElhaney R N; Monck M A; Cullis P R
Studies of highly asymmetric mixed-chain diacyl phosphatidylcholines that form mixed-interdigitated gel phases: Fourier transform infrared and 2H NMR spectroscopic studies of hydrocarbon chain conformation and orientational order in the liquid-crystalline state.
Biophysical journal 1994;67(1):197-207.
1994: Wheeler J J; Veiro J A; Cullis P R
Ionophore-mediated loading of Ca2+ into large unilamellar vesicles in response to transmembrane pH gradients.
Molecular membrane biology 1994;11(3):151-7.
1994: Boman N L; Masin D; Mayer L D; Cullis P R; Bally M B
Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing P388 tumors.
Cancer research 1994;54(11):2830-3.
1994: Devine D V; Wong K; Serrano K; Chonn A; Cullis P R
Liposome-complement interactions in rat serum: implications for liposome survival studies.
Biochimica et biophysica acta 1994;1191(1):43-51.
1994: Mui B L; Cullis P R; Pritchard P H; Madden T D
Influence of plasma on the osmotic sensitivity of large unilamellar vesicles prepared by extrusion.
The Journal of biological chemistry 1994;269(10):7364-70.
1994: Bally M B; Masin D; Nayar R; Cullis P R; Mayer L D
Transfer of liposomal drug carriers from the blood to the peritoneal cavity of normal and ascitic tumor-bearing mice.
Cancer chemotherapy and pharmacology 1994;34(2):137-46.
1993: Boman N L; Mayer L D; Cullis P R
Optimization of the retention properties of vincristine in liposomal systems.
Biochimica et biophysica acta 1993;1152(2):253-8.
1993: Harrigan P R; Wong K F; Redelmeier T E; Wheeler J J; Cullis P R
Accumulation of doxorubicin and other lipophilic amines into large unilamellar vesicles in response to transmembrane pH gradients.
Biochimica et biophysica acta 1993;1149(2):329-38.
1993: Parr M J; Bally M B; Cullis P R
The presence of GM1 in liposomes with entrapped doxorubicin does not prevent RES blockade.
Biochimica et biophysica acta 1993;1168(2):249-52.
1993: Fenske D B; Cullis P R
Acyl chain orientational order in large unilamellar vesicles: comparison with multilamellar liposomes: a 2H and 31P nuclear magnetic resonance study.
Biophysical journal 1993;64(5):1482-91.
1993: Monck M A; Bloom M; Lafleur M; Lewis R N; McElhaney R N; Cullis P R
Evidence for two pools of cholesterol in the Acholeplasma laidlawii strain B membrane: a deuterium NMR and DSC study.
Biochemistry 1993;32(12):3081-8.
1993: Mui B L; Cullis P R; Evans E A; Madden T D
Osmotic properties of large unilamellar vesicles prepared by extrusion.
Biophysical journal 1993;64(2):443-53.
1993: Mayer L D; Nayar R; Thies R L; Boman N L; Cullis P R; Bally M B
Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia.
Cancer chemotherapy and pharmacology 1993;33(1):17-24.
1992: Harrigan P R; Hope M J; Redelmeier T E; Cullis P R
Determination of transmembrane pH gradients and membrane potentials in liposomes.
Biophysical journal 1992;63(5):1336-45.
1992: Monck M A; Bloom M; Lafleur M; Lewis R N; McElhaney R N; Cullis P R
Influence of lipid composition on the orientational order in Acholeplasma laidlawii strain B membranes: a deuterium NMR study.
Biochemistry 1992;31(41):10037-43.
1992: Chonn A; Semple S C; Cullis P R
Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes.
The Journal of biological chemistry 1992;267(26):18759-65.
1992: Chakrabarti A C; Veiro J A; Wong N S; Wheeler J J; Cullis P R
Generation and characterization of iron- and barium-loaded liposomes.
Biochimica et biophysica acta 1992;1108(2):233-9.
1992: Fenske D B; Cullis P R
Chemical exchange between lamellar and non-lamellar lipid phases. A one- and two-dimensional 31P-NMR study.
Biochimica et biophysica acta 1992;1108(2):201-9.
1992: Eastman S J; Hope M J; Wong K F; Cullis P R
Influence of phospholipid asymmetry on fusion between large unilamellar vesicles.
Biochemistry 1992;31(17):4262-8.
1992: Wilschut J; Scholma J; Eastman S J; Hope M J; Cullis P R
Ca(2+)-induced fusion of phospholipid vesicles containing free fatty acids: modulation by transmembrane pH gradients.
Biochemistry 1992;31(10):2629-36.
1992: Chakrabarti A C; Clark-Lewis I; Harrigan P R; Cullis P R
Uptake of basic amino acids and peptides into liposomes in response to transmembrane pH gradients.
Biophysical journal 1992;61(1):228-34.
1991: Chonn A; Semple S C; Cullis P R
Separation of large unilamellar liposomes from blood components by a spin column procedure: towards identifying plasma proteins which mediate liposome clearance in vivo.
Biochimica et biophysica acta 1991;1070(1):215-22.
1991: Cullis P R; Bally M B; Madden T D; Mayer L D; Hope M J
pH gradients and membrane transport in liposomal systems.
Trends in biotechnology 1991;9(8):268-72.
1991: Chonn A; Cullis P R; Devine D V
The role of surface charge in the activation of the classical and alternative pathways of complement by liposomes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(12):4234-41.
1991: Eastman S J; Hope M J; Cullis P R
Transbilayer transport of phosphatidic acid in response to transmembrane pH gradients.
Biochemistry 1991;30(7):1740-5.
1990: Chakrabarti A C; Veiro J A; Wong N; Cullis P R
Use of transmembrane pH gradients and A23187 to produce dense iron liposomes.
Biochemical Society transactions 1990;18(5):946-7.
1990: Lafleur M; Cullis P R; Fine B; Bloom M
Comparison of the orientational order of lipid chains in the L alpha and HII phases.
Biochemistry 1990;29(36):8325-33.
1990: Loughrey H C; Wong K F; Choi L S; Cullis P R; Bally M B
Protein-liposome conjugates with defined size distributions.
Biochimica et biophysica acta 1990;1028(1):73-81.
1990: Loughrey H C; Choi L S; Cullis P R; Bally M B
Optimized procedures for the coupling of proteins to liposomes.
Journal of immunological methods 1990;132(1):25-35.
1990: Loughrey H C; Bally M B; Reinish L W; Cullis P R
The binding of phosphatidylglycerol liposomes to rat platelets is mediated by complement.
Thrombosis and haemostasis 1990;64(1):172-6.
1990: Thies R L; Cowens D W; Cullis P R; Bally M B; Mayer L D
Method for rapid separation of liposome-associated doxorubicin from free doxorubicin in plasma.
Analytical biochemistry 1990;188(1):65-71.
1990: Mayer L D; Tai L C; Bally M B; Mitilenes G N; Ginsberg R S; Cullis P R
Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients.
Biochimica et biophysica acta 1990;1025(2):143-51.
1990: Veiro J A; Cullis P R
A novel method for the efficient entrapment of calcium in large unilamellar phospholipid vesicles.
Biochimica et biophysica acta 1990;1025(1):109-15.
1990: Redelmeier T E; Hope M J; Cullis P R
On the mechanism of transbilayer transport of phosphatidylglycerol in response to transmembrane pH gradients.
Biochemistry 1990;29(12):3046-53.
1990: Bally M B; Nayar R; Masin D; Hope M J; Cullis P R; Mayer L D
Liposomes with entrapped doxorubicin exhibit extended blood residence times.
Biochimica et biophysica acta 1990;1023(1):133-9.
1990: Madden T D; Harrigan P R; Tai L C; Bally M B; Mayer L D; Redelmeier T E; Loughrey H C; Tilcock C P; Reinish L W; Cullis P R
The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey.
Chemistry and physics of lipids 1990;53(1):37-46.
1990: Madden T D; Janoff A S; Cullis P R
Incorporation of amphotericin B into large unilamellar vesicles composed of phosphatidylcholine and phosphatidylglycerol.
Chemistry and physics of lipids 1990;52(3-4):189-98.
1990: Mayer L D; Bally M B; Loughrey H; Masin D; Cullis P R
Liposomal vincristine preparations which exhibit decreased drug toxicity and increased activity against murine L1210 and P388 tumors.
Cancer research 1990;50(3):575-9.
1990: Harrigan P R; Madden T D; Cullis P R
Protection of liposomes during dehydration or freezing.
Chemistry and physics of lipids 1990;52(2):139-49.
1990: Bally M B; Nayar R; Masin D; Cullis P R; Mayer L D
Studies on the myelosuppressive activity of doxorubicin entrapped in liposomes.
Cancer chemotherapy and pharmacology 1990;27(1):13-9.
1989: Mayer L D; Tai L C; Ko D S; Masin D; Ginsberg R S; Cullis P R; Bally M B
Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice.
Cancer research 1989;49(21):5922-30.
1989: Lafleur M; Fine B; Sternin E; Cullis P R; Bloom M
Smoothed orientational order profile of lipid bilayers by 2H-nuclear magnetic resonance.
Biophysical journal 1989;56(5):1037-41.
1989: Redelmeier T E; Mayer L D; Wong K F; Bally M B; Cullis P R
Proton flux in large unilamellar vesicles in response to membrane potentials and pH gradients.
Biophysical journal 1989;56(2):385-93.
1989: Doerschuk C M; Gie R P; Bally M B; Cullis P R; Reinish L W
Platelet distribution in rabbits following infusion of liposomes.
Thrombosis and haemostasis 1989;61(3):392-6.
1989: Eastman S J; Wilschut J; Cullis P R; Hope M J
Intervesicular exchange of lipids with weak acid and weak base characteristics: influence of transmembrane pH gradients.
Biochimica et biophysica acta 1989;981(2):178-84.
1989: Hope M J; Redelmeier T E; Wong K F; Rodrigueza W; Cullis P R
Phospholipid asymmetry in large unilamellar vesicles induced by transmembrane pH gradients.
Biochemistry 1989;28(10):4181-7.
1989: Balazsovits J A; Mayer L D; Bally M B; Cullis P R; McDonell M; Ginsberg R S; Falk R E
Analysis of the effect of liposome encapsulation on the vesicant properties, acute and cardiac toxicities, and antitumor efficacy of doxorubicin.
Cancer chemotherapy and pharmacology 1989;23(2):81-6.
1988: Reinish L W; Bally M B; Loughrey H C; Cullis P R
Interactions of liposomes and platelets.
Thrombosis and haemostasis 1988;60(3):518-23.
1988: Madden T D; Tilcock C P; Wong K; Cullis P R
Spontaneous vesiculation of large multilamellar vesicles composed of saturated phosphatidylcholine and phosphatidylglycerol mixtures.
Biochemistry 1988;27(24):8724-30.
1988: Sternin E; Fine B; Bloom M; Tilcock C P; Wong K F; Cullis P R
Acyl chain orientational order in the hexagonal HII phase of phospholipid-water dispersions.
Biophysical journal 1988;54(4):689-94.
1988: Bally M B; Mayer L D; Loughrey H; Redelmeier T; Madden T D; Wong K; Harrigan P R; Hope M J; Cullis P R
Dopamine accumulation in large unilamellar vesicle systems induced by transmembrane ion gradients.
Chemistry and physics of lipids 1988;47(2):97-107.
1988: Mayer L D; Wong K F; Menon K; Chong C; Harrigan P R; Cullis P R
Influence of ion gradients on the transbilayer distribution of dibucaine in large unilamellar vesicles.
Biochemistry 1988;27(6):2053-60.
1988: Tilcock C P; Cullis P R; Gruner S M
Calcium-induced phase separation phenomena in multicomponent unsaturated lipid mixtures.
Biochemistry 1988;27(5):1415-20.
1987: Wong K F; Parmar Y I; Mayer L D; Pritchard P H; Cullis P R
Detection of protein-free lipoprotein analogues with an apolar lipid core by freeze-etch electron microscopy.
Biochimica et biophysica acta 1987;921(2):411-4.
1987: Loughrey H; Bally M B; Cullis P R
A non-covalent method of attaching antibodies to liposomes.
Biochimica et biophysica acta 1987;901(1):157-60.
1985: Madden T D; Bally M B; Hope M J; Cullis P R; Schieren H P; Janoff A S
Protection of large unilamellar vesicles by trehalose during dehydration: retention of vesicle contents.
Biochimica et biophysica acta 1985;817(1):67-74.
1984: Madden T D; Hope M J; Cullis P R
Influence of vesicle size and oxidase content on respiratory control in reconstituted cytochrome oxidase vesicles.
Biochemistry 1984;23(7):1413-8.
1983: Madden T D; Hope M J; Cullis P R
Lipid requirements for coupled cytochrome oxidase vesicles.
Biochemistry 1983;22(8):1970-4.

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