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Paul Cumming

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Florian Schlagenhauf; Torsten Wüstenberg; Quentin J M Huys; Jan Kalbitzer; Thorsten Kienast; Yoshitaka Kumakura; Michail Plotkin; Michael A Rapp; Michael Bauer; Anne Beck; Ralph Buchert; Hans-Georg Buchholz; Paul Cumming; Lorenz Deserno; Raymond J Dolan; Anthony A Grace; Andreas Heinz
Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence.
Bianca Jupp; Ingrid Reverte; Trevor W Robbins; Niel Saigal; Saurav Shrestha; Daniele Caprioli; Paul Cumming; Barry J Everitt; Jeffrey W Dalley
Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex.
Ingo Vernaleken; Paul Cumming; Majken Klomp; Olaf Moeller; Arne Nagels; Mardjan Raptis; Frank Rösch; Wolfgang M Schaefer; Gerhard Gründer
Vulnerability to psychotogenic effects of ketamine is associated with elevated D(2/3)-receptor availability.

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2013: Florian Schlagenhauf; Torsten Wüstenberg; Quentin J M Huys; Jan Kalbitzer; Thorsten Kienast; Yoshitaka Kumakura; Michail Plotkin; Michael A Rapp; Michael Bauer; Anne Beck; Ralph Buchert; Hans-Georg Buchholz; Paul Cumming; Lorenz Deserno; Raymond J Dolan; Anthony A Grace; Andreas Heinz
Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence.
Human brain mapping 2013;34(6):1490-9.
2013: Bianca Jupp; Ingrid Reverte; Trevor W Robbins; Niel Saigal; Saurav Shrestha; Daniele Caprioli; Paul Cumming; Barry J Everitt; Jeffrey W Dalley
Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex.
The European journal of neuroscience 2013;37(9):1519-28.
2013: Ingo Vernaleken; Paul Cumming; Majken Klomp; Olaf Moeller; Arne Nagels; Mardjan Raptis; Frank Rösch; Wolfgang M Schaefer; Gerhard Gründer
Vulnerability to psychotogenic effects of ketamine is associated with elevated D(2/3)-receptor availability.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2013;16(4):745-54.
2013: Christopher Uebleis; Serge D Van Kriekinge; Peter Bartenstein; Alexander Becker; Paul Cumming; Guido Germano; Alexander Haug; Xaver Hoyer; Rüdiger Paul Laubender; S Lehner; Franziska Schuessler; Andrei Todica; Marcus Hacker
Association between left ventricular mechanical dyssynchrony with myocardial perfusion and functional parameters in patients with left bundle branch block.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2013;20(2):253-61.
2013: Andrei Todica; Carmen Wängler; Eliane Weidl; Peter Bartenstein; G Böning; Paul Cumming; S Lehner; Stephan Nekolla; Ralf Schirrmacher; Markus Schwaiger; Marcus Hacker
Positron emission tomography in the assessment of left ventricular function in healthy rats: a comparison of four imaging methods.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2013;20(2):262-74.
2013: Paul Cumming; Gerhard Gründer; Christian la Fougère; Markus Piel; Axel Rominger; Frank Rösch; Peter Bartenstein; Hans-Georg Buchholz; Guoming Xiong; Ingo Vernaleken
Surrogate markers for cerebral blood flow correlate with [¹⁸F]-fallypride binding potential at dopamine D(2/3) receptors in human striatum.
Synapse (New York, N.Y.) 2013;67(4):199-203.
2012: Nathalie L Jansen; Friedrich W Kreth; Hans A Kretzschmar; Christian la Fougère; Jürgen Lutz; Gabriele Pöpperl; Christoph Schwartz; Peter Bartenstein; Paul Cumming; Rupert Egensperger; Sabina Eigenbrod; Vera Graute; Jörg-Christian Tonn; Niklas Thon
Prediction of oligodendroglial histology and LOH 1p/19q using dynamic [(18)F]FET-PET imaging in intracranial WHO grade II and III gliomas.
Neuro-oncology 2012;14(12):1473-80.
2012: S Lehner; Ralf Schirrmacher; Andrei Todica; Christopher Uebleis; Hao Wang; Carmen Wängler; G Böning; Stefan Brunner; Paul Cumming; Wolfgang Franz; Nadja Herbach; Tanja Herrler; Rüdiger Paul Laubender; Marcus Hacker
Temporal changes in phosphatidylserine expression and glucose metabolism after myocardial infarction: an in vivo imaging study in mice.
Molecular imaging 2012;11(6):461-70.
2012: Christopher Uebleis; Serge D Van Kriekinge; Peter Bartenstein; Alexander Becker; Paul Cumming; Alexander Haug; Stefan Hellweger; Rüdiger Paul Laubender; S Lehner; Piotr J Slomka; Hae-Young Sohn; Marcus Hacker
Left ventricular dyssynchrony assessed by gated SPECT phase analysis is an independent predictor of death in patients with advanced coronary artery disease and reduced left ventricular function not undergoing cardiac resynchronization therapy.
European journal of nuclear medicine and molecular imaging 2012;39(10):1561-9.
2012: C Uebleis; Franz von Ziegler; Peter Bartenstein; Alexander Becker; C Becker; Paul Cumming; W M Franz; M Groebner; A R Haug; S Lehner; C Rischpler; R Tegtmeyer; Marcus Hacker
Combined anatomical and functional imaging using coronary CT angiography and myocardial perfusion SPECT in symptomatic adults with abnormal origin of a coronary artery.
The international journal of cardiovascular imaging 2012;28(7):1763-74.
2012: Jan Kalbitzer; Yoshitaka Kumakura; Thomas Mell; Michail Plotkin; Gerd Bahr; Anne Beck; Ralph Buchert; Hans-Georg Buchholz; Paul Cumming; Lorenz Deserno; Andreas Heinz; Florian Schlagenhauf; Michael A Rapp
Decline in prefrontal catecholamine synthesis explains age-related changes in cognitive speed beyond regional grey matter atrophy.
European journal of nuclear medicine and molecular imaging 2012;39(9):1462-6.
2012: Erik Mille; Axel Rominger; Klaus Tatsch; Björn Wängler; Peter Bartenstein; Paul Cumming; Christian la Fougère; Guido Böning
Compensation for cranial spill-in into the cerebellum improves quantitation of striatal dopamine D₂/₃ receptors in rats with prolonged [¹⁸F]-DMFP infusions.
Synapse (New York, N.Y.) 2012;66(8):705-13.
2012: Nathalie L Jansen; Friedrich W Kreth; Juergen Lutz; Bogdana Suchorska; Jörg-Christian Tonn; Lena Armbruster; Peter Bartenstein; Paul Cumming; Sabina Eigenbrod; Vera Graute; Christian la Fougère
MRI-suspected low-grade glioma: is there a need to perform dynamic FET PET?
European journal of nuclear medicine and molecular imaging 2012;39(6):1021-9.
2012: Karen D Ersche; Naomi A Fineberg; Ulrich Müller; Edward T Bullmore; Kevin J Craig; Paul Cumming; Trevor W Robbins
Amisulpride-induced acute akathisia in OCD: an example of dysfunctional dopamine-serotonin interactions?
Journal of psychopharmacology (Oxford, England) 2012;26(6):887-90.
2012: K Virdee; Franklin I Aigbirhio; Daniele Caprioli; Paul Cumming; Tim D Fryer; Bianca Jupp; Patrick J Riss; Axel Rominger; Jeffrey W Dalley
Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders.
Neuroscience and biobehavioral reviews 2012;36(4):1188-216.
2012: Axel Rominger; Michael Soyka; Björn Wängler; Melanie Wulff; Guoming Xiong; Andreas Zwergal; Anthonin Reilhac; Peter Bartenstein; Guido Böning; Paul Cumming; Stefan Förster; Gabriele Koller; Christian la Fougère; Ole Munk; Oliver Pogarell
[18F]Fallypride PET measurement of striatal and extrastriatal dopamine D 2/3 receptor availability in recently abstinent alcoholics.
Addiction biology 2012;17(2):490-503.
2012: Vera Graute; Peter Bartenstein; Paul Cumming; Markus Hartenbach; Nathalie Jansen; Katharina Klanke; Michael Karl Scherr; Michael Seitz; Sven Thieme; Reinhold Tiling; Christopher Ubleis; Marcus Hacker
Relationship between PSA kinetics and [18F]fluorocholine PET/CT detection rates of recurrence in patients with prostate cancer after total prostatectomy.
European journal of nuclear medicine and molecular imaging 2012;39(2):271-82.
2012: Stefan Brunner; Paul Cumming; Wolfgang Michael Franz; Karin Klingel; S Lehner; Stefan G Nekolla; Martina Sauter; Andrei Todica; Christopher Ubleis; Moritz Wildgruber; G Böning; Marcus Hacker
Left ventricular functional assessment in murine models of ischemic and dilated cardiomyopathy using [18 F]FDG-PET: comparison with cardiac MRI and monitoring erythropoietin therapy.
EJNMMI research 2012;2(1):43.
2012: Paul Cumming; Per Borghammer
Molecular imaging and the neuropathologies of Parkinson's disease.
Current topics in behavioral neurosciences 2012;11():117-48.
2011: Igor Yakushev; Paul Cumming; Alex Gerhard; Matthias J Müller; Ingrid Schermuly; Mathias Schreckenberger; Peter Stoeter; Andreas Fellgiebel
Functional implications of hippocampal degeneration in early Alzheimer's disease: a combined DTI and PET study.
European journal of nuclear medicine and molecular imaging 2011;38(12):2219-27.
2011: Franz-Josef Gildehaus; Florian Haasters; Wolf Mutschler; Peter Bartenstein; Paul Cumming; Inga Drosse; Erika Wagner; Christian Zach; Matthias Schieker
Impact of indium-111 oxine labelling on viability of human mesenchymal stem cells in vitro, and 3D cell-tracking using SPECT/CT in vivo.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(6):1204-14.
2011: Alexander R Haug; Mona Mustafa; Axel Rominger; Gerwin P Schmidt; Björn Wängler; Christoph J Auernhammer; Peter Bartenstein; Paul Cumming; Burkhard Göke; Marcus Hacker
Treatment with octreotide does not reduce tumor uptake of (68)Ga-DOTATATE as measured by PET/CT in patients with neuroendocrine tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(11):1679-83.
2011: Paul Cumming
Absolute abundances and affinity states of dopamine receptors in mammalian brain: A review.
Synapse (New York, N.Y.) 2011;65(9):892-909.
2011: Paul Cumming; Daniele Caprioli; Jeffrey W Dalley
What have positron emission tomography and 'Zippy' told us about the neuropharmacology of drug addiction?
British journal of pharmacology 2011;163(8):1586-604.
2011: Mikael Palner; Celia Kjaerby; Gitte Moos Knudsen; Paul Cumming
Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat.
Neurochemistry international 2011;58(3):243-7.
2011: Christopher Uebleis; Michael Ulbrich; Roland Tegtmeyer; Franziska Schuessler; Nadine Haserueck; Johannes Siebermair; Christoph Becker; Stephan Nekolla; Paul Cumming; Peter Bartenstein; Stefan Kääb; Marcus Hacker
Electrocardiogram-gated 18F-FDG PET/CT hybrid imaging in patients with unsatisfactory response to cardiac resynchronization therapy: initial clinical results.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(1):67-71.
2010: Axel Rominger; Erik Mille; Shanshan Zhang; Guido Böning; Stefan Förster; Sebastian Nowak; Franz-Josef Gildehaus; Björn Wängler; Peter Bartenstein; Paul Cumming
Validation of the octamouse for simultaneous 18F-fallypride small-animal PET recordings from 8 mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(10):1576-83.
2010: Alexander R Haug; Christoph J Auernhammer; Björn Wängler; Gerwin P Schmidt; Christopher Uebleis; Burkhard Göke; Paul Cumming; Peter Bartenstein; Reinhold Tiling; Marcus Hacker
68Ga-DOTATATE PET/CT for the early prediction of response to somatostatin receptor-mediated radionuclide therapy in patients with well-differentiated neuroendocrine tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1349-56.
2010: Hero Bartmann; Christina Fuest; Christian la Fougere; Guoming Xiong; Theresa Just; Juli Schlichtiger; Petra Winter; Guido Böning; Björn Wängler; Anton Pekcec; Jonna Soerensen; Peter Bartenstein; Paul Cumming; Heidrun Potschka
Imaging of P-glycoprotein-mediated pharmacoresistance in the hippocampus: proof-of-concept in a chronic rat model of temporal lobe epilepsy.
Epilepsia 2010;51(9):1780-90.
2010: Ingo Vernaleken; Hildegard Janouschek; Mardjan Raptis; Sandra Hellmann; Tanja Veselinovic; Anno Bröcheler; Christian Boy; Paul Cumming; Christoph Hiemke; Frank Rösch; Wolfgang M Schäfer; Gerhard Gründer
Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(7):951-60.
2010: Axel Rominger; Erik Mille; Guido Böning; Björn Wängler; Franz Josef Gildehaus; Cornelia Arszol; Peter Bartenstein; Paul Cumming
α2-adrenergic drugs modulate the binding of [18F]fallypride to dopamine D2/3 receptors in striatum of living mouse.
Synapse (New York, N.Y.) 2010;64(8):654-7.
2010: Tim Wollenweber; Christian Zach; Christoph Rischpler; Rebekka Fischer; Sebastian Nowak; Stephan G Nekolla; Michael Gröbner; Christopher Ubleis; Gerald Assmann; Josef Müller-Höcker; Christian La Fougére; Guido Böning; Paul Cumming; Wolfgang-Michael Franz; Marcus Hacker
Myocardial perfusion imaging is feasible for infarct size quantification in mice using a clinical single-photon emission computed tomography system equipped with pinhole collimators.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2010;12(4):427-34.
2010: Tobias Saam; Axel Rominger; Sarah Wolpers; Konstantin Nikolaou; Carsten Rist; Martin Greif; Paul Cumming; Alexander Becker; Stefan Foerster; Maximilian F Reiser; Peter Bartenstein; Marcus Hacker
Association of inflammation of the left anterior descending coronary artery with cardiovascular risk factors, plaque burden and pericardial fat volume: a PET/CT study.
European journal of nuclear medicine and molecular imaging 2010;37(6):1203-12.
2010: Luciano Minuzzi; Paul Cumming
Agonist binding fraction of dopamine D2/3 receptors in rat brain: a quantitative autoradiographic study.
Neurochemistry international 2010;56(6-7):747-52.
2010: Stefan Förster; Stefan J Teipel; Christian Zach; Axel Rominger; Paul Cumming; Christian la Fougere; Igor Yakushev; Marianne Haslbeck; Harald Hampel; Peter Bartenstein; Katharina Bürger
FDG-PET mapping the brain substrates of visuo-constructive processing in Alzheimer's disease.
Journal of psychiatric research 2010;44(7):462-9.
2010: Christian la Fougère; Gabriele Pöpperl; Johannes Levin; Björn Wängler; Guido Böning; Christopher Uebleis; Paul Cumming; Peter Bartenstein; Kai Bötzel; Klaus Tatsch
The value of the dopamine D2/3 receptor ligand 18F-desmethoxyfallypride for the differentiation of idiopathic and nonidiopathic parkinsonian syndromes.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(4):581-7.
2010: Axel Rominger; Erika Wagner; Erik Mille; Guido Böning; Mouna Esmaeilzadeh; Björn Wängler; Franz-Josef Gildehaus; Sebastian Nowak; Ariane Bruche; Klaus Tatsch; Peter Bartenstein; Paul Cumming
Endogenous competition against binding of [(18)F]DMFP and [(18)F]fallypride to dopamine D(2/3) receptors in brain of living mouse.
Synapse (New York, N.Y.) 2010;64(4):313-22.
2010: Igor Yakushev; Erwan Dupont; Hans-Georg Buchholz; Julia Tillmanns; Fabian Debus; Paul Cumming; Axel Heimann; Andreas Fellgiebel; Heiko J Luhmann; Christian Landvogt; Konrad J Werhahn; Mathias Schreckenberger; Heidrun Potschka; Peter Bartenstein
In vivo imaging of dopamine receptors in a model of temporal lobe epilepsy.
Epilepsia 2010;51(3):415-22.
2010: Yoshitaka Kumakura; Ingo Vernaleken; Hans-Georg Buchholz; Per Borghammer; Erik Danielsen; Gerhard Gründer; Andreas Heinz; Peter Bartenstein; Paul Cumming
Age-dependent decline of steady state dopamine storage capacity of human brain: an FDOPA PET study.
Neurobiology of aging 2010;31(3):447-63.
2010: Yoshitaka Kumakura; Erik H Danielsen; Albert Gjedde; Ingo Vernaleken; Hans-Georg Buchholz; Andreas Heinz; Gerhard Gründer; Peter Bartenstein; Paul Cumming
Elevated [(18)F]FDOPA utilization in the periaqueductal gray and medial nucleus accumbens of patients with early Parkinson's disease.
NeuroImage 2010;49(4):2933-9.
2010: Axel Rominger; Tobias Saam; Eva Vogl; Christopher Ubleis; Christian la Fougère; Stefan Förster; Alexander Haug; Paul Cumming; Maximilian F Reiser; Konstantin Nikolaou; Peter Bartenstein; Marcus Hacker
In vivo imaging of macrophage activity in the coronary arteries using 68Ga-DOTATATE PET/CT: correlation with coronary calcium burden and risk factors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(2):193-7.
2010: P Borghammer; Karen Østergaard; Paul Cumming; Albert Gjedde; Anders Rodell; N Hall; M M Chakravarty
A deformation-based morphometry study of patients with early-stage Parkinson's disease.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2010;17(2):314-20.
2010: Stefan Förster; Johannes Rieber; Christopher Ubleis; Mayo Weiss; Peter Bartenstein; Paul Cumming; Volker Klauss; Marcus Hacker
Tc-99m sestamibi single photon emission computed tomography for guiding percutaneous coronary intervention in patients with multivessel disease: a comparison with quantitative coronary angiography and fractional flow reserve.
The international journal of cardiovascular imaging 2010;26(2):203-13.
2010: Christian la Fougère; Guido Böning; Hero Bartmann; Björn Wängler; Sebastian Nowak; Theresa Just; Erika Wagner; Petra Winter; Axel Rominger; Stefan Förster; Franz-Josef Gildehaus; Pedro Rosa-Neto; Luciano Minuzzi; Peter Bartenstein; Heidrun Potschka; Paul Cumming
Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: effects of the novel P-glycoprotein inhibitor tariquidar.
NeuroImage 2010;49(2):1406-15.
2010: Stefan Förster; Andreas Vaitl; Stefan J Teipel; Igor Yakushev; Mona Mustafa; Christian la Fougère; Axel Rominger; Paul Cumming; Peter Bartenstein; Harald Hampel; Thomas Hummel; Katharina Buerger; Walter Hundt; Silke Steinbach
Functional representation of olfactory impairment in early Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;22(2):581-91.
2010: Stefan Förster; Axel Rominger; Tobias Saam; S Wolpers; Konstantin Nikolaou; Paul Cumming; Maximilian F Reiser; Peter Bartenstein; Marcus Hacker
18F-fluoroethylcholine uptake in arterial vessel walls and cardiovascular risk factors: correlation in a PET-CT study.
Nuklearmedizin. Nuclear medicine 2010;49(4):148-53.
2010: Søren Dinesen Ostergaard; Aage Kristian Olsen Alstrup; Jan Bert Gramsbergen; Luciano Minuzzi; Kasper Pedersen; Svend B Jensen; Doris Doudet; Paul Cumming
MDMA-evoked changes in the binding of dopamine D(2) receptor ligands in striatum of rats with unilateral serotonin depletion.
Synapse (New York, N.Y.) 2010;64(1):70-82.
2009: Per Borghammer; Paul Cumming; Joel Aanerud; Stefan Förster; Albert Gjedde
Subcortical elevation of metabolism in Parkinson's disease--a critical reappraisal in the context of global mean normalization.
NeuroImage 2009;47(4):1514-21.
2009: Christopher Uebleis; Alexander Becker; Ines Griesshammer; Paul Cumming; Hans-Christoph Becker; Michael Schmidt; Peter Bartenstein; Marcus Hacker
Stable coronary artery disease: prognostic value of myocardial perfusion SPECT in relation to coronary calcium scoring--long-term follow-up.
Radiology 2009;252(3):682-90.
2008: Ingo Vernaleken; Christine Fellows; Hildegard Janouschek; Anno Bröcheler; Tanja Veselinovic; Christian Landvogt; Christian Boy; Hans-Georg Buchholz; Katja Spreckelmeyer; Peter Bartenstein; Paul Cumming; Christoph Hiemke; Frank Rösch; Wolfgang Schäfer; Dean F Wong; Gerhard Gründer
Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone).
Journal of clinical psychopharmacology 2008;28(6):608-17.
2008: Thorsten Kienast; Ahmad R Hariri; Florian Schlagenhauf; Jana Wrase; Philipp Sterzer; Hans Georg Buchholz; Michael N Smolka; Gerhard Gründer; Paul Cumming; Yoshitaka Kumakura; Peter Bartenstein; Raymond J Dolan; Andreas Heinz
Dopamine in amygdala gates limbic processing of aversive stimuli in humans.
Nature neuroscience 2008;11(12):1381-2.
2008: Ingo Vernaleken; Paul Cumming; Gerhard Gründer
Imaging studies - differential action of typical and atypical antipsychotics in a network perspective.
Pharmacopsychiatry 2008;41 Suppl 1():S60-9.
2008: Thorsten Kienast; Thomas Siessmeier; Jana Wrase; Dieter F Braus; Michael N Smolka; Hans-Georg Buchholz; Michael A Rapp; Mathias Schreckenberger; Frank Rösch; Paul Cumming; Gerhard Gruender; Karl Mann; Peter Bartenstein; Andreas Heinz
Ratio of dopamine synthesis capacity to D2 receptor availability in ventral striatum correlates with central processing of affective stimuli.
European journal of nuclear medicine and molecular imaging 2008;35(6):1147-58.
2008: P Borghammer; M Vafaee; K Ostergaard; A Rodell; C Bailey; Paul Cumming
Effect of memantine on CBF and CMRO2 in patients with early Parkinson's disease.
Acta neurologica Scandinavica 2008;117(5):317-23.
2008: Ingo Vernaleken; Yoshitaka Kumakura; Hans-Georg Buchholz; Thomas Siessmeier; Ralf-Dieter Hilgers; Peter Bartenstein; Paul Cumming; Gerhard Gründer
Baseline [18F]-FDOPA kinetics are predictive of haloperidol-induced changes in dopamine turnover and cognitive performance: A positron emission tomography study in healthy subjects.
NeuroImage 2008;40(3):1222-31.
2008: Christian Landvogt; Eugen Mengel; Peter Bartenstein; Hans-Georg Buchholz; Mathias Schreckenberger; Thomas Siessmeier; Armin Scheurich; Reinhold Feldmann; Josef Weglage; Paul Cumming; Fred Zepp; Kurt Ullrich
Reduced cerebral fluoro-L-dopamine uptake in adult patients suffering from phenylketonuria.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(4):824-31.
2008: Svend B Jensen; Roberto Di Santo; Aage Kristian Olsen; Kasper Pedersen; Roberta Costi; Roberto Cirilli; Paul Cumming
Synthesis and cerebral uptake of 1-(1-[(11)C]methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A.
Journal of medicinal chemistry 2008;51(6):1617-22.
2007: Ingo Vernaleken; Hans-Georg Buchholz; Yoshitaka Kumakura; Thomas Siessmeier; Peter Stoeter; Peter Bartenstein; Paul Cumming; Gerhard Gründer
'Prefrontal' cognitive performance of healthy subjects positively correlates with cerebral FDOPA influx: an exploratory [18F]-fluoro-L-DOPA-PET investigation.
Human brain mapping 2007;28(10):931-9.
2007: Yoshitaka Kumakura; Paul Cumming; Ingo Vernaleken; Hans-Georg Buchholz; Thomas Siessmeier; Andreas Heinz; Thorsten Kienast; Peter Bartenstein; Gerhard Gründer
Elevated [18F]fluorodopamine turnover in brain of patients with schizophrenia: an [18F]fluorodopa/positron emission tomography study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(30):8080-7.
2007: Jan Bert Gramsbergen; Paul Cumming
Serotonin mediates rapid changes of striatal glucose and lactate metabolism after systemic 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") administration in awake rats.
Neurochemistry international 2007;51(1):8-15.
2007: Paul Cumming; Mette Møller; Kjeld Benda; Luciano Minuzzi; Steen Jakobsen; Svend B Jensen; Bente Pakkenberg; Anette K Stark; Jan Bert Gramsbergen; Mette F Andreasen; Aage Kristian Olsen
A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on serotonin markers in Göttingen minipig brain.
Synapse (New York, N.Y.) 2007;61(7):478-87.
2007: Kelin Mezzomo; Paul Cumming; Luciano Minuzzi
Comparison of the binding distribution of agonist and antagonist ligands for histamine H3 receptors in pig brain by quantitative autoradiography.
European journal of pharmacology 2007;564(1-3):75-9.
2007: Kasper Pedersen; Mette Simonsen; Søren D Østergaard; Ole Lajord Munk; Pedro Rosa-Neto; Aage Kristian Olsen; Svend B Jensen; Arne Møller; Paul Cumming
Mapping the amphetamine-evoked changes in [11C]raclopride binding in living rat using small animal PET: modulation by MAO-inhibition.
NeuroImage 2007;35(1):38-46.
2007: Hideaki Watanabe; Masaharu Sakoh; Flemming Andersen; Anders Rodell; Jens Christian Sørensen; Leif Østergaard; Kim Mouridsen; Paul Cumming
Statistical mapping of effects of middle cerebral artery occlusion (MCAO) on blood flow and oxygen consumption in porcine brain.
Journal of neuroscience methods 2007;160(1):109-15.
2007: Ingo Vernaleken; Carsten Weibrich; Thomas Siessmeier; Hans-Georg Buchholz; Frank Rösch; Andreas Heinz; Paul Cumming; Peter Stoeter; Peter Bartenstein; Gerhard Gründer
Asymmetry in dopamine D(2/3) receptors of caudate nucleus is lost with age.
NeuroImage 2007;34(3):870-8.
2007: Nanna Marie Lind; Anette Moustgaard; Jacob Jelsing; Gábor Vajta; Paul Cumming; Axel Kornerup Hansen
The use of pigs in neuroscience: modeling brain disorders.
Neuroscience and biobehavioral reviews 2007;31(5):728-51.
2006: Steen Jakobsen; Kasper Pedersen; Donald Frederick Smith; Svend B Jensen; Ole Lajord Munk; Paul Cumming
Detection of alpha2-adrenergic receptors in brain of living pig with 11C-yohimbine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(12):2008-15.
2006: Mads D Pedersen; Luciano Minuzzi; Martin Wirenfeldt; Michael Meldgaard; Carina Slidsborg; Paul Cumming; Bente Finsen
Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain.
The European journal of neuroscience 2006;24(4):991-1000.
2006: Thomas Siessmeier; Thorsten Kienast; Jana Wrase; Jennifer Lynne Larsen; Dieter F Braus; Michael N Smolka; Hans-Georg Buchholz; Mathias Schreckenberger; Frank Rösch; Paul Cumming; Karl Mann; Peter Bartenstein; Andreas Heinz
Net influx of plasma 6-[18F]fluoro-L-DOPA (FDOPA) to the ventral striatum correlates with prefrontal processing of affective stimuli.
The European journal of neuroscience 2006;24(1):305-13.
2006: Steen Jakobsen; Gitte Munkebo Kodahl; Aage Kristian Olsen; Paul Cumming
Synthesis, radiolabeling and in vivo evaluation of [11C]RAL-01, a potential phosphodiesterase 5 radioligand.
Nuclear medicine and biology 2006;33(5):593-7.
2006: Peter Iversen; Dorthe Aagaard Hansen; Dirk Bender; Anders Rodell; Ole Lajord Munk; Paul Cumming; Susanne Keiding
Peripheral benzodiazepine receptors in the brain of cirrhosis patients with manifest hepatic encephalopathy.
European journal of nuclear medicine and molecular imaging 2006;33(7):810-6.
2006: Donald Frederick Smith; Katalin Marthi; Ole Lajord Munk; Paul Cumming; Søren B Hansen; Steen Jakobsen
PET neuroimaging of [11C]mirtazapine enantiomers in pigs.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2006;16(5):350-7.
2006: Donald Frederick Smith; Suzan Dyve; Luciano Minuzzi; Steen Jakobsen; Ole Lajord Munk; Katalin Marthi; Paul Cumming
Inhibition of [11C]mirtazapine binding by alpha2-adrenoceptor antagonists studied by positron emission tomography in living porcine brain.
Synapse (New York, N.Y.) 2006;59(8):463-71.
2006: Paul Cumming; Mads D Pedersen; Luciano Minuzzi; Kelin Mezzomo; Erik H Danielsen; Peter Iversen; Dorthe Aagaard; Susanne Keiding; Ole Lajord Munk; Bente Finsen
Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography.
Synapse (New York, N.Y.) 2006;59(7):418-26.
2006: Svend B Jensen; Aage Kristian Olsen; Kasper Pedersen; Paul Cumming
Effect of monoamine oxidase inhibition on amphetamine-evoked changes in dopamine receptor availability in the living pig: a dual tracer PET study with [11C]harmine and [11C]raclopride.
Synapse (New York, N.Y.) 2006;59(7):427-34.
2006: Ingo Vernaleken; Yoshitaka Kumakura; Paul Cumming; Hans-Georg Buchholz; Thomas Siessmeier; Peter Stoeter; Matthias J Müller; Peter Bartenstein; Gerhard Gründer
Modulation of [18F]fluorodopa (FDOPA) kinetics in the brain of healthy volunteers after acute haloperidol challenge.
NeuroImage 2006;30(4):1332-9.
2006: Luciano Minuzzi; Aage Kristian Olsen; Dirk Bender; Sidse M Arnfred; Rebecca Grant; Erik H Danielsen; Paul Cumming
Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: comparison with results in vivo.
Synapse (New York, N.Y.) 2006;59(4):211-9.
2006: Doris J Doudet; Pedro Rosa-Neto; Ole Lajord Munk; Thomas J Ruth; Salma Jivan; Paul Cumming
Effect of age on markers for monoaminergic neurons of normal and MPTP-lesioned rhesus monkeys: a multi-tracer PET study.
NeuroImage 2006;30(1):26-35.
2006: Yoshitaka Kumakura; Albert Gjedde; Erik H Danielsen; Søren Christensen; Paul Cumming
Dopamine storage capacity in caudate and putamen of patients with early Parkinson's disease: correlation with asymmetry of motor symptoms.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(3):358-70.
2005: Nanna Marie Lind; Albert Gjedde; Anette Moustgaard; Aage Kristian Olsen; Svend B Jensen; Steen Jakobsen; Sidse M Arnfred; Axel Kornerup Hansen; Ralf Hemmingsen; Paul Cumming
Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs.
Behavioural brain research 2005;164(2):172-7.
2005: Per Borghammer; Yoshitaka Kumakura; Paul Cumming
Fluorodopa F 18 positron emission tomography and the progression of Parkinson disease.
Archives of neurology 2005;62(9):1480; author reply 1480-1.
2005: Andreas Heinz; Thomas Siessmeier; Jana Wrase; Hans-Georg Buchholz; Gerhard Gründer; Yoshitaka Kumakura; Paul Cumming; Mathias Schreckenberger; Michael N Smolka; Frank Rösch; Karl Mann; Peter Bartenstein
Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients.
The American journal of psychiatry 2005;162(8):1515-20.
2005: Flemming Andersen; Hideaki Watanabe; Carsten R Bjarkam; Erik H Danielsen; Paul Cumming
Pig brain stereotaxic standard space: mapping of cerebral blood flow normative values and effect of MPTP-lesioning.
Brain research bulletin 2005;66(1):17-29.
2005: Mette Sørensen; Michael R Horsman; Paul Cumming; Ole Lajord Munk; Susanne Keiding
Effect of intratumoral heterogeneity in oxygenation status on FMISO PET, autoradiography, and electrode Po2 measurements in murine tumors.
International journal of radiation oncology, biology, physics 2005;62(3):854-61.
2005: Yoshitaka Kumakura; Ingo Vernaleken; Gerhard Gründer; Peter Bartenstein; Albert Gjedde; Paul Cumming
PET studies of net blood-brain clearance of FDOPA to human brain: age-dependent decline of [18F]fluorodopamine storage capacity.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(7):807-19.
2005: Luciano Minuzzi; George Nomikos; Mark R Wade; Svend B Jensen; Aage Kristian Olsen; Paul Cumming
Interaction between LSD and dopamine D2/3 binding sites in pig brain.
Synapse (New York, N.Y.) 2005;56(4):198-204.
2005: Thomas Siessmeier; Yun Zhou; Hans-Georg Buchholz; Christian Landvogt; Ingo Vernaleken; Markus Piel; Ralf Schirrmacher; Frank Rösch; Mathias Schreckenberger; Dean F Wong; Paul Cumming; Gerhard Gründer; Peter Bartenstein
Parametric mapping of binding in human brain of D2 receptor ligands of different affinities.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(6):964-72.
2005: Jacob Jelsing; Aage Kristian Olsen; Paul Cumming; Albert Gjedde; Axel Kornerup Hansen; Sidse M Arnfred; Ralf Hemmingsen; Bente Pakkenberg
A volumetric screening procedure for the Göttingen minipig brain.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2005;162(4):428-35.
2005: Pedro Rosa-Neto; Hans C Lou; Paul Cumming; Ole Pryds; Hanne Karrebaek; Jytte Lunding; Albert Gjedde
Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder.
NeuroImage 2005;25(3):868-76.
2005: Nanna Marie Lind; Aage Kristian Olsen; Anette Moustgaard; Svend B Jensen; Steen Jakobsen; Axel Kornerup Hansen; Sidse M Arnfred; Ralf Hemmingsen; Albert Gjedde; Paul Cumming
Mapping the amphetamine-evoked dopamine release in the brain of the Göttingen minipig.
Brain research bulletin 2005;65(1):1-9.
2005: Albert Gjedde; Dean F Wong; Pedro Rosa-Neto; Paul Cumming
Mapping neuroreceptors at work: on the definition and interpretation of binding potentials after 20 years of progress.
International review of neurobiology 2005;63():1-20.
2004: Pedro Rosa-Neto; Albert Gjedde; Aage Kristian Olsen; Svend B Jensen; Ole Lajord Munk; Hideaki Watanabe; Paul Cumming
MDMA-evoked changes in [11C]raclopride and [11C]NMSP binding in living pig brain.
Synapse (New York, N.Y.) 2004;53(4):222-33.
2004: Pedro Rosa-Neto; Aage Kristian Olsen; Albert Gjedde; Hideaki Watanabe; Paul Cumming
MDMA-evoked changes in cerebral blood flow in living porcine brain: correlation with hyperthermia.
Synapse (New York, N.Y.) 2004;53(4):214-21.
2004: Yoshitaka Kumakura; E H Danielsen; A Reilhac; Albert Gjedde; Paul Cumming
Levodopa effect on [18F]fluorodopa influx to brain: normal volunteers and patients with Parkinson's disease.
Acta neurologica Scandinavica 2004;110(3):188-95.
2004: Dirk Bender; Aage Kristian Olsen; M K Marthi; Donald Frederick Smith; Paul Cumming
PET evaluation of the uptake of N-[11C]methyl CP-643,051, an NK1 receptor antagonist, in the living porcine brain.
Nuclear medicine and biology 2004;31(6):699-704.
2004: Pedro Rosa-Neto; Doris J Doudet; Paul Cumming
Gradients of dopamine D1- and D2/3-binding sites in the basal ganglia of pig and monkey measured by PET.
NeuroImage 2004;22(3):1076-83.
2004: M S Vafaee; Karen Østergaard; Niels Sunde; Albert Gjedde; Erik Dupont; Paul Cumming
Focal changes of oxygen consumption in cerebral cortex of patients with Parkinson's disease during subthalamic stimulation.
NeuroImage 2004;22(2):966-74.
2004: Hans C Lou; Pedro Rosa-Neto; Ole Pryds; Hanne Karrebaek; Jytte Lunding; Paul Cumming; Albert Gjedde
ADHD: increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow.
Developmental medicine and child neurology 2004;46(3):179-83.
2003: Svend B Jensen; Donald Frederick Smith; Dirk Bender; Steen Jakobsen; Dan Peters; Elsebet Ø Nielsen; Gunnar M Olsen; Jørgen Scheel-Krüger; Alan Wilson; Paul Cumming
[11C]-NS 4194 versus [11C]-DASB for PET imaging of serotonin transporters in living porcine brain.
Synapse (New York, N.Y.) 2003;49(3):170-7.
2003: Paul Cumming; Pedro Rosa-Neto; Hideaki Watanabe; Donald Smith; Dirk Bender; Paul B S Clarke; Albert Gjedde
Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain.
NeuroImage 2003;19(3):1127-36.
2003: Paul Cumming; Nicholas Gillings; Svend B Jensen; Carsten R Bjarkam; Albert Gjedde
Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs.
Nuclear medicine and biology 2003;30(5):547-53.
2003: Gerhard Gründer; Ingo Vernaleken; Matthias J Müller; Eugen Davids; Nilufar Heydari; Hans-Georg Buchholz; Peter Bartenstein; Ole Lajord Munk; Peter Stoeter; Dean F Wong; Albert Gjedde; Paul Cumming
Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(4):787-94.
2002: Amynah Pradhan; Paul Cumming; Paul B S Clarke
[125I]Epibatidine-labelled nicotinic receptors in the extended striatum and cerebral cortex: lack of association with serotonergic afferents.
Brain research 2002;954(2):227-36.
2002: Paul Cumming; Dean F Wong; Robert F Dannals; Nicholas Gillings; John Hilton; Ursula Scheffel; Albert Gjedde
The competition between endogenous dopamine and radioligands for specific binding to dopamine receptors.
Annals of the New York Academy of Sciences 2002;965():440-50.
2002: Pedro Rosa-Neto; Hans Lou; Paul Cumming; Ole Pryds; Albert Gjedde
Methylphenidate-evoked potentiation of extracellular dopamine in the brain of adolescents with premature birth: correlation with attentional deficit.
Annals of the New York Academy of Sciences 2002;965():434-9.
2002: Paul Cumming; Dean F Wong; Nicholas Gillings; John Hilton; Ursula Scheffel; Albert Gjedde
Specific binding of [(11)C]raclopride and N-[(3)H]propyl-norapomorphine to dopamine receptors in living mouse striatum: occupancy by endogenous dopamine and guanosine triphosphate-free G protein.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(5):596-604.
2002: Annette Møller Dall; Erik H Danielsen; Jens Christian Sørensen; Flemming Andersen; Arne Møller; Jens Zimmer; Albert Gjedde; Paul Cumming
Quantitative [18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned minipigs.
Cell transplantation 2002;11(8):733-46.
2001: Hideaki Watanabe; Flemming Andersen; Claus Ziegler Simonsen; S M Evans; Albert Gjedde; Paul Cumming
MR-based statistical atlas of the Göttingen minipig brain.
NeuroImage 2001;14(5):1089-96.
2001: Erik H Danielsen; Donald Frederick Smith; Flemming Andersen; Antony D Gee; Dirk Bender; Søren B Hansen; Flemming Hermansen; Leif Østergaard; Paul Cumming; Albert Gjedde
FDOPA metabolism in the adult porcine brain: influence of tracer circulation time and VOI selection on estimates of striatal DOPA decarboxylation.
Journal of neuroscience methods 2001;111(2):157-68.
2001: Alain Dagher; C Bleicher; John A D Aston; Roger Gunn; Paul B S Clarke; Paul Cumming
Reduced dopamine D1 receptor binding in the ventral striatum of cigarette smokers.
Synapse (New York, N.Y.) 2001;42(1):48-53.
2001: Paul Cumming; Ole Lajord Munk; Doris J Doudet
Loss of metabolites from monkey striatum during PET with FDOPA.
Synapse (New York, N.Y.) 2001;41(3):212-8.
2001: Erik H Danielsen; D Smith; Flemming Hermansen; Albert Gjedde; Paul Cumming
Acute neuroleptic stimulates DOPA decarboxylase in porcine brain in vivo.
Synapse (New York, N.Y.) 2001;41(2):172-5.
2001: Paul Cumming; Erik H Danielsen; M Vafaee; Lise Falborg; E Steffensen; Jens Christian Sørensen; Nicholas Gillings; Dirk Bender; Katalin Marthi; Flemming Andersen; Ole Lajord Munk; D Smith; Arne Møller; Albert Gjedde
Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts.
Acta neurologica Scandinavica 2001;103(5):309-15.
2001: Donald Frederick Smith; Dirk Bender; Katalin Marthi; Paul Cumming; Søren B Hansen; Dan Peters; E O Nielsen; Jørgen Scheel-Krüger; Albert Gjedde
Synthesis and evaluation of racemic [(11)C]NS2456 and enantiomers as selective serotonin reuptake radiotracers for PET.
Nuclear medicine and biology 2001;28(3):265-70.
2001: Nicholas Gillings; Dirk Bender; Lise Falborg; Katalin Marthi; Ole Lajord Munk; Paul Cumming
Kinetics of the metabolism of four PET radioligands in living minipigs.
Nuclear medicine and biology 2001;28(1):97-104.
2000: K Ishizu; Donald Frederick Smith; Dirk Bender; Erik H Danielsen; Søren B Hansen; Dean F Wong; Paul Cumming; Albert Gjedde
Positron emission tomography of radioligand binding in porcine striatum in vivo: haloperidol inhibition linked to endogenous ligand release.
Synapse (New York, N.Y.) 2000;38(1):87-101.
2000: Olivier Rousset; P Deep; Hiroto Kuwabara; A C Evans; Albert Gjedde; Paul Cumming
Effect of partial volume correction on estimates of the influx and cerebral metabolism of 6-[(18)F]fluoro-L-dopa studied with PET in normal control and Parkinson's disease subjects.
Synapse (New York, N.Y.) 2000;37(2):81-9.
2000: Erik H Danielsen; Paul Cumming; Flemming Andersen; Dirk Bender; T Brevig; Lise Falborg; A Gee; Nicholas Gillings; Søren B Hansen; Flemming Hermansen; J Johansen; T E Johansen; A Dahl-Jørgensen; Hugo A Jørgensen; M Meyer; Ole Lajord Munk; E B Pedersen; PH Poulsen; Anders Rodell; Masaharu Sakoh; Claus Ziegler Simonsen; Donald Frederick Smith; Jens Christian Sørensen; L Ostergård; Jens Zimmer; Albert Gjedde; A Møller
The DaNeX study of embryonic mesencephalic, dopaminergic tissue grafted to a minipig model of Parkinson's disease: preliminary findings of effect of MPTP poisoning on striatal dopaminergic markers.
Cell transplantation 2000;9(2):247-59.
2000: T Marenco; S Bernstein; Paul Cumming; Paul B S Clarke
Effects of nicotine and chlorisondamine on cerebral glucose utilization in immobilized and freely-moving rats.
British journal of pharmacology 2000;129(1):147-55.
1999: P Deep; Alain Dagher; Abbas F Sadikot; Albert Gjedde; Paul Cumming
Stimulation of dopa decarboxylase activity in striatum of healthy human brain secondary to NMDA receptor antagonism with a low dose of amantadine.
Synapse (New York, N.Y.) 1999;34(4):313-8.
1999: Paul Cumming; Fuji Yokoi; A Chen; P Deep; Alain Dagher; David C Reutens; F Kapczinski; Dean F Wong; Albert Gjedde
Pharmacokinetics of radiotracers in human plasma during positron emission tomography.
Synapse (New York, N.Y.) 1999;34(2):124-34.
1999: Erik H Danielsen; Donald Frederick Smith; Antony D Gee; T K Venkatachalam; Søren B Hansen; Flemming Hermansen; Albert Gjedde; Paul Cumming
Cerebral 6-[(18)F]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography.
Synapse (New York, N.Y.) 1999;33(4):247-58.
1999: Paul Cumming; J Reith; Albert Gjedde
Cocaine withdrawal and the cerebral influx of [18F]fluoro-L-DOPA (FDOPA)
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(4):395-8.
1998: Gabriel Léger; Albert Gjedde; Hiroto Kuwabara; M Guttman; Paul Cumming
Effect of catechol-O-methyltransferase inhibition on brain uptake of [18F]fluorodopa: implications for compartmental modelling and clinical usefulness.
Synapse (New York, N.Y.) 1998;30(4):351-61.
1998: Paul Cumming; Ariel R Ase; Hiroto Kuwabara; Albert Gjedde
[3H]DOPA formed from [3H]tyrosine in living rat brain is not committed to dopamine synthesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(5):491-9.
1998: J Reith; Paul Cumming; Albert Gjedde
Enhanced [3H]DOPA and [3H]dopamine turnover in striatum and frontal cortex in vivo linked to glutamate receptor antagonism.
Journal of neurochemistry 1998;70(5):1979-85.
1998: Paul Cumming; Albert Gjedde
Compartmental analysis of dopa decarboxylation in living brain from dynamic positron emission tomograms.
Synapse (New York, N.Y.) 1998;29(1):37-61.
1997: P Deep; Hiroto Kuwabara; Albert Gjedde; Paul Cumming
The kinetic behaviour of [3H]DOPA in living rat brain investigated by compartmental modelling of static autoradiograms.
Journal of neuroscience methods 1997;78(1-2):157-68.
1997: Paul Cumming; P Deep; Olivier Rousset; A Evans; Albert Gjedde
On the rate of decarboxylation of dopa to dopamine in living mammalian brain.
Annals of the New York Academy of Sciences 1997;835():274-308.
1997: Paul Cumming; Ariel R Ase; C Laliberté; Hiroto Kuwabara; Albert Gjedde
In vivo regulation of DOPA decarboxylase by dopamine receptors in rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(11):1254-60.
1997: P Deep; Albert Gjedde; Paul Cumming
On the accuracy of an [18F]FDOPA compartmental model: evidence for vesicular storage of [18F]fluorodopamine in vivo.
Journal of neuroscience methods 1997;76(2):157-65.
1997: Paul Cumming; Albert Gjedde; J Reith
Controversies arising from recent FDOPA articles.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(8):1267-71.
1997: Paul Cumming; V Ljubic-Thibal; C Laliberté; Mirko Diksic
The effect of unilateral neurotoxic lesions to serotonin fibres in the medial forebrain bundle on the metabolism of [3H]DOPA in the telencephalon of the living rat.
Brain research 1997;747(1):60-9.
1995: Paul Cumming; Ariel R Ase; Mirko Diksic; J Harrison; D Jolly; Hiroto Kuwabara; C Laliberté; Albert Gjedde
Metabolism and blood-brain clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat.
Biochemical pharmacology 1995;50(7):943-6.
1995: Paul Cumming; Hiroto Kuwabara; Ariel R Ase; Albert Gjedde
Regulation of DOPA decarboxylase activity in brain of living rat.
Journal of neurochemistry 1995;65(3):1381-90.
1995: Hiroto Kuwabara; Paul Cumming; Y Yasuhara; Gabriel Léger; M Guttman; Mirko Diksic; Alan C Evans; Albert Gjedde
Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1226-31.
1994: J Reith; C Benkelfat; A Sherwin; Y Yasuhara; Hiroto Kuwabara; Frederick Andermann; S Bachneff; Paul Cumming; Mirko Diksic; S E Dyve; P Etienne; Alan C Evans; S Lal; M Shevell; G Savard; Dean F Wong; G Chouinard; Albert Gjedde
Elevated dopa decarboxylase activity in living brain of patients with psychosis.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11651-4.
1994: Paul Cumming; C Laliberté; Albert Gjedde
Distribution of histamine H3 binding in forebrain of mouse and guinea pig.
Brain research 1994;664(1-2):276-9.
1994: Paul Cumming; Hiroto Kuwabara; Albert Gjedde
A kinetic analysis of 6-[18F]fluoro-L-dihydroxyphenylalanine metabolism in the rat.
Journal of neurochemistry 1994;63(5):1675-82.
1993: Albert Gjedde; Gabriel Léger; Paul Cumming; Y Yasuhara; Alan C Evans; M Guttman; Hiroto Kuwabara
Striatal L-dopa decarboxylase activity in Parkinson's disease in vivo: implications for the regulation of dopamine synthesis.
Journal of neurochemistry 1993;61(4):1538-41.
1993: Paul Cumming; Albert Gjedde
Kinetics of the uptake of [3H]paroxetine in the rat brain.
Synapse (New York, N.Y.) 1993;15(2):124-9.
1993: Paul Cumming; Gabriel Léger; Hiroto Kuwabara; Albert Gjedde
Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine ([18F]Fdopa) in humans.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(4):668-75.
1993: Paul Cumming; S R Vincent
Altered histamine H3 binding in rat forebrain after reserpine treatment.
Brain research 1993;602(1):53-6.
1993: H Hoshi; Hiroto Kuwabara; Gabriel Léger; Paul Cumming; M Guttman; Albert Gjedde
6-[18F]fluoro-L-dopa metabolism in living human brain: a comparison of six analytical methods.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):57-69.
1993: Hiroto Kuwabara; Paul Cumming; J Reith; Gabriel Léger; Mirko Diksic; Alan C Evans; Albert Gjedde
Human striatal L-dopa decarboxylase activity estimated in vivo using 6-[18F]fluoro-dopa and positron emission tomography: error analysis and application to normal subjects.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):43-56.
1992: Paul Cumming; S R Vincent
Inhibition of histamine-N-methyltransferase (HNMT) by fragments of 9-amino-1,2,3,4-tetrahydroacridine (tacrine) and by beta-carbolines.
Biochemical pharmacology 1992;44(5):989-92.