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Richard Cummings

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TOP 3
David F Smith; Richard D Cummings
Application of microarrays for deciphering the structure and function of the human glycome.
Elsenoor J Klaver; Georg Kraal; Helene Kringel; Loes M Kuijk; Lisa C Laan; Gerd Bouma; Richard D Cummings; Sandra J van Vliet; Irma Van Die
Trichuris suis-induced modulation of human dendritic cell function is glycan-mediated.
Hazuki E Miwa; Yinghui Song; Richard Alvarez; Richard D Cummings; Pamela Stanley
The bisecting GlcNAc in cell growth control and tumor progression.

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All Publications

2013: David F Smith; Richard D Cummings
Application of microarrays for deciphering the structure and function of the human glycome.
Molecular & cellular proteomics : MCP 2013;12(4):902-12.
2013: Elsenoor J Klaver; Georg Kraal; Helene Kringel; Loes M Kuijk; Lisa C Laan; Gerd Bouma; Richard D Cummings; Sandra J van Vliet; Irma Van Die
Trichuris suis-induced modulation of human dendritic cell function is glycan-mediated.
International journal for parasitology 2013;43(3-4):191-200.
2012: Hazuki E Miwa; Yinghui Song; Richard Alvarez; Richard D Cummings; Pamela Stanley
The bisecting GlcNAc in cell growth control and tumor progression.
Glycoconjugate journal 2012;29(8-9):609-18.
2012: Yingchun Wang; David R Archer; Hyojung Choo; Xiaokun Ding; Shawn M Jobe; Tongzhong Ju; Rongjuan Mi; Richard D Cummings
Platelet biogenesis and functions require correct protein O-glycosylation.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(40):16143-8.
2012: Xuezheng Song; David F Smith; Richard D Cummings
Nonenzymatic release of free reducing glycans from glycosphingolipids.
Analytical biochemistry 2012;429(1):82-7.
2012: Hua Su; Conner B Carter; Richard D Cummings; Otto Fröhlich; Guangping Chen
Glycoforms of UT-A3 urea transporter with poly-N-acetyllactosamine glycosylation have enhanced transport activity.
American journal of physiology. Renal physiology 2012;303(2):F201-8.
2012: Alicia C Castonguay; Richard D Cummings; Yi Lasanajak; Linda J Olson; David Smith; Xuezheng Song; Nancy M Dahms
The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates.
Glycobiology 2012;22(7):983-96.
2012: Vered Padler-Karavani; Melitta Schachner; Richard Schwab; David Smith; Xuezheng Song; Andrea Verhagen; Hai Yu; Xi Chen; Jiansong Cheng; Harshal A Chokhawala; Richard D Cummings; Raoul J de Groot; Shengshu Huang; Nancy Hurtado-Ziola; Ralf Kleene; Martijn A Langereis; Yi Lasanajak; Haruo Matsuda; Saddam Muthana; Ajit Varki
Cross-comparison of protein recognition of sialic acid diversity on two novel sialoglycan microarrays.
The Journal of biological chemistry 2012;287(27):22593-608.
2012: Andrew Borgert; Richard D Cummings; Jamie Heimburg-Molinaro; Tongzhong Ju; Yi Lasanajak; Mian Liu; Govind Ragupathi; David Smith; Xuezheng Song; Pamela Thompson; George Barany; David Live
Deciphering structural elements of mucin glycoprotein recognition.
ACS chemical biology 2012;7(6):1031-9.
2012: Rajindra P Aryal; Tongzhong Ju; Richard D Cummings
Tight complex formation between Cosmc chaperone and its specific client non-native T-synthase leads to enzyme activity and client-driven dissociation.
The Journal of biological chemistry 2012;287(19):15317-29.
2012: Sean R Stowell; Anne M Winkler; James C Zimring; Cheryl L Maier; Nicole H Smith; C Maridith Arthur; Richard D Cummings; Kathryn R Girard-Pierce; Jeanne E Hendrickson
Initiation and regulation of complement during hemolytic transfusion reactions.
Clinical & developmental immunology 2012;2012():307093.
2012: Jamie Heimburg-Molinaro; Yi Lasanajak; David Smith; Xuezheng Song; Mary Tappert; Gillian Air; Richard D Cummings
Probing virus-glycan interactions using glycan microarrays.
Methods in molecular biology (Clifton, N.J.) 2012;808():251-67.
2012: Xuezheng Song; Nancy M Dahms; Jamie Heimburg-Molinaro; David Smith; Richard D Cummings
Preparation of a mannose-6-phosphate glycan microarray through fluorescent derivatization, phosphorylation, and immobilization of natural high-mannose N-glycans and application in ligand identification of P-type lectins.
Methods in molecular biology (Clifton, N.J.) 2012;808():137-48.
2012: Xuezheng Song; Jamie Heimburg-Molinaro; David Smith; Richard D Cummings
Glycan microarrays.
Methods in molecular biology (Clifton, N.J.) 2012;800():163-71.
2011: Konrad C Bradley; Xi Chen; Richard D Cummings; Summer E Galloway; Jamie Heimburg-Molinaro; Yi Lasanajak; David Smith; Xuezheng Song; Ganesh R Talekar; Hai Yu; David A Steinhauer
Analysis of influenza virus hemagglutinin receptor binding mutants with limited receptor recognition properties and conditional replication characteristics.
Journal of virology 2011;85(23):12387-98.
2011: Carmen Aranzamendi; Fabrizio Bruschi; Lorena Chiumiento; Richard D Cummings; Montse Jansen; Titia Kortbeek; Elena Pinelli; David Smith; Boris Tefsen; Irma Van Die
Glycan microarray profiling of parasite infection sera identifies the LDNF glycan as a potential antigen for serodiagnosis of trichinellosis.
Experimental parasitology 2011;129(3):221-6.
2011: Xuezheng Song; Mary M Tappert; Vinod K Tiwari; Hai Yu; Haojie Zheng; Gillian M Air; Hongzhi Cao; Xi Chen; Harshal A Chokhawala; Richard D Cummings; Yi Lasanajak; David Smith
A sialylated glycan microarray reveals novel interactions of modified sialic acids with proteins and viruses.
The Journal of biological chemistry 2011;286(36):31610-22.
2011: Konrad C Bradley; Cheryl A Jones; Stephen M Tompkins; Ralph A Tripp; Rupert J Russell; Marie R Gramer; Jamie Heimburg-Molinaro; David Smith; Richard D Cummings; David A Steinhauer
Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1).
Virology 2011;413(2):169-82.
2011: Jamie Heimburg-Molinaro; Xuezheng Song; David Smith; Richard D Cummings
Preparation and analysis of glycan microarrays.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2011;Chapter 12():Unit12.10.
2011: Qian Sun; Tongzhong Ju; Richard D Cummings
The transmembrane domain of the molecular chaperone Cosmc directs its localization to the endoplasmic reticulum.
The Journal of biological chemistry 2011;286(13):11529-42.
2011: Tongzhong Ju; Baoyun Xia; Rajindra P Aryal; Wenyi Wang; Yingchun Wang; Xiaokun Ding; Rongjuan Mi; Miao He; Richard D Cummings
A novel fluorescent assay for T-synthase activity.
Glycobiology 2011;21(3):352-62.
2011: Tongzhong Ju; Vivianne I Otto; Richard D Cummings
The Tn antigen-structural simplicity and biological complexity.
Angewandte Chemie (International ed. in English) 2011;50(8):1770-91.
2011: Juan P Cerliani; Sean R Stowell; Iván D Mascanfroni; Connie M Arthur; Richard D Cummings; Gabriel A Rabinovich
Expanding the universe of cytokines and pattern recognition receptors: galectins and glycans in innate immunity.
Journal of clinical immunology 2011;31(1):10-21.
2011: Els J M Van Damme; David Smith; Richard D Cummings; Willy J Peumans
Glycan arrays to decipher the specificity of plant lectins.
Advances in experimental medicine and biology 2011;705():757-67.
2011: Xuezheng Song; Yi Lasanajak; Baoyun Xia; Jamie Heimburg-Molinaro; Jeanne M Rhea; Hong Ju; Chunmei Zhao; Ross J Molinaro; Richard D Cummings; David Smith
Shotgun glycomics: a microarray strategy for functional glycomics.
Nature methods 2011;8(1):85-90.
2010: Winston Y Lee; Dominique A Weber; Oskar Laur; Sean R Stowell; Ingrid McCall; Rakieb Andargachew; Richard D Cummings; Charles A Parkos
The role of cis dimerization of signal regulatory protein alpha (SIRPalpha) in binding to CD47.
The Journal of biological chemistry 2010;285(49):37953-63.
2010: Wei Huang; Xinyu Zhang; Tongzhong Ju; Richard D Cummings; Lai-Xi Wang
Expeditious chemoenzymatic synthesis of CD52 glycopeptide antigens.
Organic & biomolecular chemistry 2010;8(22):5224-33.
2010: Jan G M Bolscher; Judith Brevoord; Kamran Nazmi; Tongzhong Ju; Enno C I Veerman; Joanna A E van Wijk; Richard D Cummings; Irma van Die
Solid-phase synthesis of a pentavalent GalNAc-containing glycopeptide (Tn antigen) representing the nephropathy-associated IgA hinge region.
Carbohydrate research 2010;345(14):1998-2003.
2010: Anne Leppänen; Ville Parviainen; Elina Ahola-Iivarinen; Nisse Kalkkinen; Richard D Cummings
Human L-selectin preferentially binds synthetic glycosulfopeptides modeled after endoglycan and containing tyrosine sulfate residues and sialyl Lewis x in core 2 O-glycans.
Glycobiology 2010;20(9):1170-85.
2010: Venkata R Krishnamurthy; Ann Dougherty; Medha Kamat; Xuezheng Song; Richard D Cummings; Elliot L Chaikof
Synthesis of an Fmoc-threonine bearing core-2 glycan: a building block for PSGL-1 via Fmoc-assisted solid-phase peptide synthesis.
Carbohydrate research 2010;345(11):1541-7.
2010: Venkata R Krishnamurthy; John T Wilson; WANXING CUI; XueZheng Song; Yi Lasanajak; Richard D Cummings; Elliot L Chaikof
Chemoselective immobilization of peptides on abiotic and cell surfaces at controlled densities.
Langmuir : the ACS journal of surfaces and colloids 2010;26(11):7675-8.
2010: Yingchun Wang; Tongzhong Ju; Xiaokun Ding; Baoyun Xia; Wenyi Wang; Lijun Xia; Miao He; Richard D Cummings
Cosmc is an essential chaperone for correct protein O-glycosylation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(20):9228-33.
2010: Marcelo Dias-Baruffi; Sean R Stowell; Shuh Chyung Song; Connie M Arthur; Moonjae Cho; Lilian C Rodrigues; Marlise A B Montes; Marcos A Rossi; Judith A James; Rodger P McEver; Richard D Cummings
Differential expression of immunomodulatory galectin-1 in peripheral leukocytes and adult tissues and its cytosolic organization in striated muscle.
Glycobiology 2010;20(5):507-20.
2010: Sean R Stowell; Connie M Arthur; Marcelo Dias-Baruffi; Lilian C Rodrigues; JEAN-PHILIPPE GOURDINE; Jamie Heimburg-Molinaro; Tongzhong Ju; Ross J Molinaro; Carlos Rivera-Marrero; Baoyun Xia; David Smith; Richard D Cummings
Innate immune lectins kill bacteria expressing blood group antigen.
Nature medicine 2010;16(3):295-301.
2010: He Dong; Xuezheng Song; Yi Lasanajak; Richard D Cummings; Elliot L Chaikof
Facile construction of fluorescent peptide microarrays: One-step fluorescent derivatization of sub-microscale peptide aldehydes for selective terminal immobilization.
Analytical biochemistry 2010;398(1):132-4.
2010: Caroline M W van Stijn; Marloes van den Broek; Lonneke Vervelde; Richard A Alvarez; Richard D Cummings; Boris Tefsen; Irma Van Die
Vaccination-induced IgG response to Galalpha1-3GalNAc glycan epitopes in lambs protected against Haemonchus contortus challenge infection.
International journal for parasitology 2010;40(2):215-22.
2010: Rajindra P Aryal; Tongzhong Ju; Richard D Cummings
The endoplasmic reticulum chaperone Cosmc directly promotes in vitro folding of T-synthase.
The Journal of biological chemistry 2010;285(4):2456-62.
2010: Anne Leppänen; Richard D Cummings
Fluorescence-based solid-phase assays to study glycan-binding protein interactions with glycoconjugates.
Methods in enzymology 2010;478():241-64.
2010: David Smith; Xuezheng Song; Richard D Cummings
Use of glycan microarrays to explore specificity of glycan-binding proteins.
Methods in enzymology 2010;480():417-44.
2010: Tongzhong Ju; Richard D Cummings
Functional assays for the molecular chaperone cosmc.
Methods in enzymology 2010;479():107-22.
2010: Irma Van Die; Richard D Cummings
Glycan gimmickry by parasitic helminths: a strategy for modulating the host immune response?
Glycobiology 2010;20(1):2-12.
2009: Xuezheng Song; Yi Lasanajak; Carlos Rivera-Marrero; Anthony Luyai; Margaret Willard; David Smith; Richard D Cummings
Generation of a natural glycan microarray using 9-fluorenylmethyl chloroformate (FmocCl) as a cleavable fluorescent tag.
Analytical biochemistry 2009;395(2):151-60.
2009: Richard N Bohnsack; Xuezheng Song; Linda J Olson; Mariko Kudo; Russell R Gotschall; William M Canfield; Richard D Cummings; David Smith; Nancy M Dahms
Cation-independent mannose 6-phosphate receptor: a composite of distinct phosphomannosyl binding sites.
The Journal of biological chemistry 2009;284(50):35215-26.
2009: Xuezheng Song; Yi Lasanajak; Linda J Olson; Marielle Boonen; Nancy M Dahms; Stuart Kornfeld; Richard D Cummings; David Smith
Glycan microarray analysis of P-type lectins reveals distinct phosphomannose glycan recognition.
The Journal of biological chemistry 2009;284(50):35201-14.
2009: Ajit Varki; Richard D Cummings; Jeffrey D Esko; Hudson H Freeze; Pamela Stanley; Jamey D Marth; Carolyn R Bertozzi; Gerald W Hart; Marilynn E Etzler
Symbol nomenclature for glycan representation.
Proteomics 2009;9(24):5398-9.
2009: Ponnusamy Babu; Simon J North; Jihye Jang-Lee; Sara Chalabi; Kathryn Mackerness; Sean R Stowell; Richard D Cummings; Sara Rankin; Anne Dell; Stuart M Haslam
Structural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodology.
Glycoconjugate journal 2009;26(8):975-86.
2009: Richard D Cummings
The repertoire of glycan determinants in the human glycome.
Molecular bioSystems 2009;5(10):1087-104.
2009: Xuezheng Song; Yi Lasanajak; Baoyun Xia; David Smith; Richard D Cummings
Fluorescent glycosylamides produced by microscale derivatization of free glycans for natural glycan microarrays.
ACS chemical biology 2009;4(9):741-50.
2009: Anthony Luyai; Yi Lasanajak; David Smith; Richard D Cummings; Xuezheng Song
Facile preparation of fluorescent neoglycoproteins using p-nitrophenyl anthranilate as a heterobifunctional linker.
Bioconjugate chemistry 2009;20(8):1618-24.
2009: Gerard Hernandez Mir; Jari Helin; Kari-Pekka Skarp; Richard D Cummings; Antti A Mäkitie; Risto Renkonen; Anne Leppänen
Glycoforms of human endothelial CD34 that bind L-selectin carry sulfated sialyl Lewis x capped O- and N-glycans.
Blood 2009;114(3):733-41.
2009: Junya Mitoma; Tatsuo Miyazaki; Mark Sutton-Smith; Misa Suzuki; Hideo Saito; Jiunn-Chern Yeh; Takehiro Kawano; Ole Hindsgaul; Peter H Seeberger; Maria Panico; Stuart M Haslam; Howard R Morris; Richard D Cummings; Anne Dell; Minoru Fukuda
The N-glycolyl form of mouse sialyl Lewis X is recognized by selectins but not by HECA-452 and FH6 antibodies that were raised against human cells.
Glycoconjugate journal 2009;26(5):511-23.
2009: Stephan von Gunten; David Smith; Richard D Cummings; Stefan Riedel; Sylvia Miescher; Alexander Schaub; Robert G Hamilton; Bruce S Bochner
Intravenous immunoglobulin contains a broad repertoire of anticarbohydrate antibodies that is not restricted to the IgG2 subclass.
The Journal of allergy and clinical immunology 2009;123(6):1268-76.e15.
2009: Baoyun Xia; Christa L Feasley; Goverdhan P Sachdev; David Smith; Richard D Cummings
Glycan reductive isotope labeling for quantitative glycomics.
Analytical biochemistry 2009;387(2):162-70.
2009: Sean R Stowell; Sougata Karmakar; Connie M Arthur; Tongzhong Ju; Lilian C Rodrigues; Thalita B Riul; Marcelo Dias-Baruffi; Jonathan Miner; Rodger P McEver; Richard D Cummings
Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane.
Molecular biology of the cell 2009;20(5):1408-18.
2009: Cynthia Perrine; Tongzhong Ju; Richard D Cummings; Thomas A Gerken
Systematic determination of the peptide acceptor preferences for the human UDP-Gal:glycoprotein-alpha-GalNAc beta 3 galactosyltransferase (T-synthase).
Glycobiology 2009;19(3):321-8.
2009: Sean R Stowell; Moonjae Cho; Christa L Feasley; Connie M Arthur; Xuezheng Song; Jennifer K Colucci; Sougata Karmakar; Padmaja Mehta; Marcelo Dias-Baruffi; Rodger P McEver; Richard D Cummings
Ligand reduces galectin-1 sensitivity to oxidative inactivation by enhancing dimer formation.
The Journal of biological chemistry 2009;284(8):4989-99.
2009: Xuezheng Song; Baoyun Xia; Sean R Stowell; Yi Lasanajak; David Smith; Richard D Cummings
Novel fluorescent glycan microarray strategy reveals ligands for galectins.
Chemistry & biology 2009;16(1):36-47.
2008: Roger Lawrence; Sara K Olson; Robert E Steele; Lianchun Wang; Rahul Warrior; Richard D Cummings; Jeffrey D Esko
Evolutionary differences in glycosaminoglycan fine structure detected by quantitative glycan reductive isotope labeling.
The Journal of biological chemistry 2008;283(48):33674-84.
2008: Jianxin Fu; Holger Gerhardt; Karlien Hermans; Lacramioara Ivanciu; Tongzhong Ju; Xiaowei Liu; Florea Lupu; J Michael McDaniel; Samuel McGee; Annelii Ny; Emma Nye; Maria I Ramirez; Robert Silasi-Mansat; Baoyun Xia; Peter Carmeliet; Richard D Cummings; Lijun Xia
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice.
The Journal of clinical investigation 2008;118(11):3725-37.
2008: Daniel G Cerri; Lílian C Rodrigues; Sean R Stowell; Daniela D Araujo; Mariana C Coelho; Sibere R Oliveira; João Bizario; Richard D Cummings; Marcelo Dias-Baruffi; Maria Cristina R Costa
Degeneration of dystrophic or injured skeletal muscles induces high expression of Galectin-1.
Glycobiology 2008;18(11):842-50.
2008: Sougata Karmakar; Sean R Stowell; Richard D Cummings; Rodger P McEver
Galectin-1 signaling in leukocytes requires expression of complex-type N-glycans.
Glycobiology 2008;18(10):770-8.
2008: Ajit Varki; Linda G Baum; Susan L Bellis; Richard D Cummings; Jeffrey D Esko; Gerald W Hart; Robert J Linhardt; John B Lowe; Rodger P McEver; Arun Srivastava; Rita Sarkar
Working group report: the roles of glycans in hemostasis, inflammation and vascular biology.
Glycobiology 2008;18(10):747-9.
2008: Tongzhong Ju; Rajindra P Aryal; Caleb J Stowell; Richard D Cummings
Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc.
The Journal of cell biology 2008;182(3):531-42.
2008: Sean R Stowell; Connie M Arthur; Kristin A Slanina; John Horton; David Smith; Richard D Cummings
Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain.
The Journal of biological chemistry 2008;283(29):20547-59.
2008: Stephen Farrand; Eileen M Hotze; Paul Friese; Susan Kay Hollingshead; David Smith; Richard D Cummings; George L Dale; Rodney K Tweten
Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain.
Biochemistry 2008;47(27):7097-107.
2008: Ziad S Kawar; Thomas K Johnson; Suvi Natunen; John B Lowe; Richard D Cummings
PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen.
Glycobiology 2008;18(6):441-6.
2008: Margaret L Zupancic; Matthew Frieman; David Smith; Richard A Alvarez; Richard D Cummings; Brendan P Cormack
Glycan microarray analysis of Candida glabrata adhesin ligand specificity.
Molecular microbiology 2008;68(3):547-59.
2008: Arkadiusz G Klopocki; Tadayuki Yago; Padmaja Mehta; Jun Yang; Tao Wu; Anne Leppänen; Nicolai V Bovin; Richard D Cummings; Cheng Zhu; Rodger P McEver
Replacing a lectin domain residue in L-selectin enhances binding to P-selectin glycoprotein ligand-1 but not to 6-sulfo-sialyl Lewis x.
The Journal of biological chemistry 2008;283(17):11493-500.
2008: Sean R Stowell; Connie M Arthur; Padmaja Mehta; Kristen A Slanina; Ola Blixt; Hakon Leffler; David Smith; Richard D Cummings
Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens.
The Journal of biological chemistry 2008;283(15):10109-23.
2008: Qinlong Zheng; Irma Van Die; Richard D Cummings
A novel alpha1,2-fucosyltransferase (CE2FT-2) in Caenorhabditis elegans generates H-type 3 glycan structures.
Glycobiology 2008;18(4):290-302.
2008: Tongzhong Ju; Grainger S Lanneau; Tripti Gautam; Yingchun Wang; Baoyun Xia; Sean R Stowell; Margaret T Willard; Wenyi Wang; Jonathan Y Xia; Rosemary E Zuna; Zoltan Laszik; Doris M Benbrook; Marie H Hanigan; Richard D Cummings
Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc.
Cancer research 2008;68(6):1636-46.
2008: Sean R Stowell; Yuning Qian; Sougata Karmakar; Natalia S Koyama; Marcelo Dias-Baruffi; Hakon Leffler; Rodger P McEver; Richard D Cummings
Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3091-102.
2008: Xuezheng Song; Baoyun Xia; Yi Lasanajak; David Smith; Richard D Cummings
Quantifiable fluorescent glycan microarrays.
Glycoconjugate journal 2008;25(1):15-25.
2007: Maria G Castillo; Xiao-Jun Wu; Nathalie Dinguirard; A Kwame Nyame; Richard D Cummings; Timothy P Yoshino
Surface membrane proteins of Biomphalaria glabrata embryonic cells bind fucosyl determinants on the tegumental surface of Schistosoma mansoni primary sporocysts.
The Journal of parasitology 2007;93(4):832-40.
2007: Mary Amonsen; David Smith; Richard D Cummings; Gillian M Air
Human parainfluenza viruses hPIV1 and hPIV3 bind oligosaccharides with alpha2-3-linked sialic acids that are distinct from those bound by H5 avian influenza virus hemagglutinin.
Journal of virology 2007;81(15):8341-5.
2007: Guangyu An; Bo Wei; Baoyun Xia; J Michael McDaniel; Tongzhong Ju; Richard D Cummings; Jonathan Braun; Lijun Xia
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans.
The Journal of experimental medicine 2007;204(6):1417-29.
2007: Kiem Nguyen; Irma Van Die; Kiely M Grundahl; Ziad S Kawar; Richard D Cummings
Molecular cloning and characterization of the Caenorhabditis elegans alpha1,3-fucosyltransferase family.
Glycobiology 2007;17(6):586-99.
2007: Susanne Carlsson; Christopher T Oberg; Michael C Carlsson; Anders Sundin; Ulf J Nilsson; David Smith; Richard D Cummings; Jenny Almkvist; Anna Karlsson; Hakon Leffler
Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface.
Glycobiology 2007;17(6):663-76.
2007: Eduard Condac; Robert Silasi-Mansat; Stanley D Kosanke; Trenton R Schoeb; Rheal A Towner; Florea Lupu; Richard D Cummings; Myron E Hinsdale
Polycystic disease caused by deficiency in xylosyltransferase 2, an initiating enzyme of glycosaminoglycan biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(22):9416-21.
2007: Suzannah A Williams; Lijun Xia; Richard D Cummings; Rodger P McEver; Pamela Stanley
Fertilization in mouse does not require terminal galactose or N-acetylglucosamine on the zona pellucida glycans.
Journal of cell science 2007;120(Pt 8):1341-9.
2007: Kshama Kumari; Shelly Gulati; David Smith; Upma Gulati; Richard D Cummings; Gillian M Air
Receptor binding specificity of recent human H3N2 influenza viruses.
Virology journal 2007;4():42.
2007: Baoyun Xia; Goverdhan P Sachdev; Richard D Cummings
Pseudomonas aeruginosa mucoid strain 8830 binds glycans containing the sialyl-Lewis x epitope.
Glycoconjugate journal 2007;24(1):87-95.
2007: Sean R Stowell; Sougata Karmakar; Caleb J Stowell; Marcelo Dias-Baruffi; Rodger P McEver; Richard D Cummings
Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells.
Blood 2007;109(1):219-27.
2006: Dexter V Reneer; Sarah A Kearns; Tadayuki Yago; Jonathan Sims; Richard D Cummings; Rodger P McEver; Jason A Carlyon
Characterization of a sialic acid- and P-selectin glycoprotein ligand-1-independent adhesin activity in the granulocytotropic bacterium Anaplasma phagocytophilum.
Cellular microbiology 2006;8(12):1972-84.
2006: Ellis van Liempt; Christine M C Bank; Padmaja Mehta; Juan Jesús Garciá-Vallejo; Ziad S Kawar; Rudolf Geyer; Richard A Alvarez; Richard D Cummings; Yvette van Kooyk; Irma Van Die
Specificity of DC-SIGN for mannose- and fucose-containing glycans.
FEBS letters 2006;580(26):6123-31.
2006: Tongzhong Ju; Qinlong Zheng; Richard D Cummings
Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans.
Glycobiology 2006;16(10):947-58.
2006: Young Mee Kim; Kyung-Il Park; Kwang-Sik Choi; Richard A Alvarez; Richard D Cummings; Moonjae Cho
Lectin from the Manila clam Ruditapes philippinarum is induced upon infection with the protozoan parasite Perkinsus olseni.
The Journal of biological chemistry 2006;281(37):26854-64.
2006: Joshua J Rychak; B Li; Scott T Acton; Anne Leppänen; Richard D Cummings; Klaus Ley; Alexander L Klibanov
Selectin ligands promote ultrasound contrast agent adhesion under shear flow.
Molecular pharmaceutics 2006;3(5):516-24.
2006: Vladimíra Marková; Karel Smetana; Gabriela Jeníková; Jitka Láchová; Veronika Krejciríková; Martin Poplstein; Milan Fábry; Jirí Brynda; Richard A Alvarez; Richard D Cummings; Petr Maly
Role of the carbohydrate recognition domains of mouse galectin-4 in oligosaccharide binding and epitope recognition and expression of galectin-4 and galectin-6 in mouse cells and tissues.
International journal of molecular medicine 2006;18(1):65-76.
2006: Irma Van Die; Richard D Cummings
Glycans modulate immune responses in helminth infections and allergy.
Chemical immunology and allergy 2006;90():91-112.
2005: Baoyun Xia; Ziad S Kawar; Tongzhong Ju; Richard A Alvarez; Goverdhan P Sachdev; Richard D Cummings
Versatile fluorescent derivatization of glycans for glycomic analysis.
Nature methods 2005;2(11):845-50.
2005: Tongzhong Ju; Richard D Cummings
Protein glycosylation: chaperone mutation in Tn syndrome.
Nature 2005;437(7063):1252.
2005: Sougata Karmakar; Richard D Cummings; Rodger P McEver
Contributions of Ca2+ to galectin-1-induced exposure of phosphatidylserine on activated neutrophils.
The Journal of biological chemistry 2005;280(31):28623-31.
2005: Baoyun Xia; James A Royall; Gautam Damera; Goverdhan P Sachdev; Richard D Cummings
Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis.
Glycobiology 2005;15(8):747-75.
2005: Ziad S Kawar; Stuart M Haslam; Howard R Morris; Anne Dell; Richard D Cummings
Novel poly-GalNAcbeta1-4GlcNAc (LacdiNAc) and fucosylated poly-LacdiNAc N-glycans from mammalian cells expressing beta1,4-N-acetylgalactosaminyltransferase and alpha1,3-fucosyltransferase.
The Journal of biological chemistry 2005;280(13):12810-9.
2005: Anne Leppänen; Sean R Stowell; Ola Blixt; Richard D Cummings
Dimeric galectin-1 binds with high affinity to alpha2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans.
The Journal of biological chemistry 2005;280(7):5549-62.
2004: Ola Blixt; Steven R Head; Tony Mondala; Christopher N Scanlan; Margaret E Huflejt; Richard Alvarez; Marian C. Bryan; Fabio Fazio; Daniel A Calarese; James Stevens; Nahid Razi; David J Stevens; John J Skehel; Irma Van Die; Dennis R Burton; Ian A Wilson; Richard D Cummings; Nicolai Bovin; Chi-Huey Wong; James C Paulson
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17033-8.
2004: Vivianne I Otto; Thomas Schürpf; Gerd Folkers; Richard D Cummings
Sialylated complex-type N-glycans enhance the signaling activity of soluble intercellular adhesion molecule-1 in mouse astrocytes.
The Journal of biological chemistry 2004;279(34):35201-9.
2004: Timo K van den Berg; Henk Honing; Niels Franke; Alexandra Van Remoortere; Wietske E C M Schiphorst; Fu-Tong Liu; André M Deelder; Richard D Cummings; Cornelis H Hokke; Irma Van Die
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1902-7.
2004: A Kwame Nyame; Ziad S Kawar; Richard D Cummings
Antigenic glycans in parasitic infections: implications for vaccines and diagnostics.
Archives of biochemistry and biophysics 2004;426(2):182-200.
2004: Lijun Xia; Tongzhong Ju; Andrew D Westmuckett; Guangyu An; Lacramioara Ivanciu; J Michael McDaniel; Florea Lupu; Richard D Cummings; Rodger P McEver
Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.
The Journal of cell biology 2004;164(3):451-9.
2004: Sean R Stowell; Marcelo Dias-Baruffi; Leena Penttilä; Ossi Renkonen; A Kwame Nyame; Richard D Cummings
Human galectin-1 recognition of poly-N-acetyllactosamine and chimeric polysaccharides.
Glycobiology 2004;14(2):157-67.
2003: Lonneke Vervelde; Nicole Bakker; F N J Kooyman; A W C A Cornelissen; Christine M C Bank; A Kwame Nyame; Richard D Cummings; Irma Van Die
Vaccination-induced protection of lambs against the parasitic nematode Haemonchus contortus correlates with high IgG antibody responses to the LDNF glycan antigen.
Glycobiology 2003;13(11):795-804.
2003: Jason A Carlyon; Mustafa Akkoyunlu; Lijun Xia; Tadayuki Yago; Tian Wang; Richard D Cummings; Rodger P McEver; Erol Fikrig
Murine neutrophils require alpha1,3-fucosylation but not PSGL-1 for productive infection with Anaplasma phagocytophilum.
Blood 2003;102(9):3387-95.
2003: Marcelo Dias-Baruffi; Hui Zhu; Moonjae Cho; Sougata Karmakar; Rodger P McEver; Richard D Cummings
Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosis.
The Journal of biological chemistry 2003;278(42):41282-93.
2003: Tadayuki Yago; Anne Leppänen; Jason A Carlyon; Mustafa Akkoyunlu; Sougata Karmakar; Erol Fikrig; Richard D Cummings; Rodger P McEver
Structurally distinct requirements for binding of P-selectin glycoprotein ligand-1 and sialyl Lewis x to Anaplasma phagocytophilum and P-selectin.
The Journal of biological chemistry 2003;278(39):37987-97.
2003: Anne Leppänen; Tadayuki Yago; Vivianne I Otto; Rodger P McEver; Richard D Cummings
Model glycosulfopeptides from P-selectin glycoprotein ligand-1 require tyrosine sulfation and a core 2-branched O-glycan to bind to L-selectin.
The Journal of biological chemistry 2003;278(29):26391-400.
2003: Irma Van Die; Sandra J van Vliet; A Kwame Nyame; Richard D Cummings; Christine M C Bank; Ben J Appelmelk; Teunis B H Geijtenbeek; Yvette van Kooyk
The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.
Glycobiology 2003;13(6):471-8.
2003: A Kwame Nyame; Fred A Lewis; Barbara L Doughty; Rodrigo Correa-Oliveira; Richard D Cummings
Immunity to schistosomiasis: glycans are potential antigenic targets for immune intervention.
Experimental parasitology 2003;104(1-2):1-13.
2003: Alexandra Van Remoortere; Christine M C Bank; A Kwame Nyame; Richard D Cummings; André M Deelder; Irma Van Die
Schistosoma mansoni-infected mice produce antibodies that cross-react with plant, insect, and mammalian glycoproteins and recognize the truncated biantennaryN-glycan Man3GlcNAc2-R.
Glycobiology 2003;13(3):217-25.
2003: Lijun Xia; Vishwanath Ramachandran; J Michael McDaniel; Kiem N Nguyen; Richard D Cummings; Rodger P McEver
N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin.
Blood 2003;101(2):552-9.
2002: Tongzhong Ju; Richard D Cummings
A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16613-8.
2002: Marcin M A Kobzdej; Anne Leppänen; Vishwanath Ramachandran; Richard D Cummings; Rodger P McEver
Discordant expression of selectin ligands and sialyl Lewis x-related epitopes on murine myeloid cells.
Blood 2002;100(13):4485-94.
2002: Qinlong Zheng; Irma Van Die; Richard D Cummings
Molecular cloning and characterization of a novel alpha 1,2-fucosyltransferase (CE2FT-1) from Caenorhabditis elegans.
The Journal of biological chemistry 2002;277(42):39823-32.
2002: Anne Leppanen; Leena Penttila; Ossi Renkonen; Rodger P McEver; Richard D Cummings
Glycosulfopeptides with O-glycans containing sialylated and polyfucosylated polylactosamine bind with low affinity to P-selectin.
The Journal of biological chemistry 2002;277(42):39749-59.
2002: A Kwame Nyame; Timothy P Yoshino; Richard D Cummings
Differential expression of LacdiNAc, fucosylated LacdiNAc, and Lewis x glycan antigens in intramolluscan stages of Schistosoma mansoni.
The Journal of parasitology 2002;88(5):890-7.
2002: Ziad S Kawar; Irma Van Die; Richard D Cummings
Molecular cloning and enzymatic characterization of a UDP-GalNAc:GlcNAc(beta)-R beta1,4-N-acetylgalactosaminyltransferase from Caenorhabditis elegans.
The Journal of biological chemistry 2002;277(38):34924-32.
2002: Anne E R Hicks; Anne Leppänen; Richard D Cummings; Rodger P McEver; Paul G Hellewell; Keith E Norman
Glycosulfopeptides modeled on P-selectin glycoprotein ligand 1 inhibit P-selectin-dependent leukocyte rolling in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(11):1461-2.
2002: Tadayuki Yago; Anne Leppänen; Haiying Qiu; Warren D Marcus; Matthias U Nollert; Cheng Zhu; Richard D Cummings; Rodger P McEver
Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow.
The Journal of cell biology 2002;158(4):787-99.
2002: Bruce Walcheck; Anne Leppanen; Richard D Cummings; Randall N Knibbs; Lloyd M Stoolman; Shelia R Alexander; Polly E Mattila; Rodger P McEver
The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin.
Blood 2002;99(11):4063-9.
2002: Lijun Xia; Markus Sperandio; Tadayuki Yago; J Michael McDaniel; Richard D Cummings; Sonia Pearson-White; Klaus Ley; Rodger P McEver
P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow.
The Journal of clinical investigation 2002;109(7):939-50.
2002: Carlos A Rivera-Marrero; Jeffrey D Ritzenthaler; Sarah A Newburn; Jesse Roman; Richard D Cummings
Molecular cloning and expression of a novel glycolipid sulfotransferase in Mycobacterium tuberculosis.
Microbiology (Reading, England) 2002;148(Pt 3):783-92.
2002: Tongzhong Ju; Kevin Brewer; Anil D'Souza; Richard D Cummings; William M Canfield
Cloning and expression of human core 1 beta1,3-galactosyltransferase.
The Journal of biological chemistry 2002;277(1):178-86.
2002: Tongzhong Ju; Richard D Cummings; William M Canfield
Purification, characterization, and subunit structure of rat core 1 Beta1,3-galactosyltransferase.
The Journal of biological chemistry 2002;277(1):169-77.
2001: Vishwanath Ramachandran; Tadayuki Yago; T K Epperson; M M Kobzdej; Matthias U Nollert; Richard D Cummings; Cheng Zhu; Rodger P McEver
Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10166-71.
2001: Matthias Eberl; Jan A M Langermans; Richard Vervenne; A Kwame Nyame; Richard D Cummings; Alan Thomas; Patricia S Coulson; R Alan Wilson
Antibodies to glycans dominate the host response to schistosome larvae and eggs: is their role protective or subversive?
The Journal of infectious diseases 2001;183(8):1238-47.
2000: Anne Leppänen; S P White; Jari Helin; Rodger P McEver; Richard D Cummings
Binding of glycosulfopeptides to P-selectin requires stereospecific contributions of individual tyrosine sulfate and sugar residues.
The Journal of biological chemistry 2000;275(50):39569-78.
2000: A Kwame Nyame; Anne Leppänen; B J Bogitsh; Richard D Cummings
Antibody responses to the fucosylated LacdiNAc glycan antigen in Schistosoma mansoni-infected mice and expression of the glycan among schistosomes.
Experimental parasitology 2000;96(4):202-12.
2000: J J Keusch; Stephen M Manzella; K A Nyame; Richard D Cummings; Jacques U Baenziger
Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of alpha 1, 4-glycosyltransferases conserved in plants, insects, and mammals.
The Journal of biological chemistry 2000;275(33):25315-21.
2000: J J Keusch; Stephen M Manzella; K A Nyame; Richard D Cummings; Jacques U Baenziger
Expression cloning of a new member of the ABO blood group glycosyltransferases, iGb3 synthase, that directs the synthesis of isoglobo-glycosphingolipids.
The Journal of biological chemistry 2000;275(33):25308-14.
2000: Stephen J Stray; Richard D Cummings; Gillian M Air
Influenza virus infection of desialylated cells.
Glycobiology 2000;10(7):649-58.
2000: T K Epperson; Kamala D Patel; Rodger P McEver; Richard D Cummings
Noncovalent association of P-selectin glycoprotein ligand-1 and minimal determinants for binding to P-selectin.
The Journal of biological chemistry 2000;275(11):7839-53.
2000: Irma Van Die; Richard D Cummings; A Van Tetering; Cornelis H Hokke; Carolien A M Koeleman; DH van den Eijnden
Identification of a novel UDP-Glc:GlcNAc beta1-->4-glucosyltransferase in Lymnaea stagnalis that may be involved in the synthesis of complex-type oligosaccharide chains.
Glycobiology 2000;10(3):263-71.
1999: Irma Van Die; V Gomord; F N J Kooyman; Timo K van den Berg; Richard D Cummings; Lonneke Vervelde
Core alpha1-->3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus infected sheep.
FEBS letters 1999;463(1-2):189-93.
1999: Vishwanath Ramachandran; Matthias U Nollert; H Qiu; W J Liu; Richard D Cummings; Cheng Zhu; Rodger P McEver
Tyrosine replacement in P-selectin glycoprotein ligand-1 affects distinct kinetic and mechanical properties of bonds with P- and L-selectin.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13771-6.
1999: Richard D Cummings; A Kwame Nyame
Schistosome glysoconjugates.
Biochimica et biophysica acta 1999;1455(2-3):363-74.
1999: A Kwame Nyame; Anne Leppanen; RA Debose-Boyd; Richard D Cummings
Mice infected with Schistosoma mansoni generate antibodies to LacdiNAc (GalNAc beta 1-->4GlcNAc) determinants.
Glycobiology 1999;9(10):1029-35.
1999: Anne Leppänen; Padmaja Mehta; Ying-Bin Ouyang; Tongzhong Ju; Jari Helin; Kevin L Moore; Irma Van Die; William M Canfield; Rodger P McEver; Richard D Cummings
A novel glycosulfopeptide binds to P-selectin and inhibits leukocyte adhesion to P-selectin.
The Journal of biological chemistry 1999;274(35):24838-48.
1999: Richard D Cummings
Structure and function of the selectin ligand PSGL-1.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1999;32(5):519-28.
1998: P Mehta; Richard D Cummings; Rodger P McEver
Affinity and kinetic analysis of P-selectin binding to P-selectin glycoprotein ligand-1.
The Journal of biological chemistry 1998;273(49):32506-13.
1998: RA Debose-Boyd; A Kwame Nyame; Richard D Cummings
Molecular cloning and characterization of an alpha1,3 fucosyltransferase, CEFT-1, from Caenorhabditis elegans.
Glycobiology 1998;8(9):905-17.
1998: RA Debose-Boyd; A Kwame Nyame; D P Jasmer; Richard D Cummings
The ruminant parasite Haemonchus contortus expresses an alpha1,3-fucosyltransferase capable of synthesizing the Lewis x and sialyl Lewis x antigens.
Glycoconjugate journal 1998;15(8):789-98.
1998: A Kwame Nyame; RA Debose-Boyd; T D Long; Victor Tsang; Richard D Cummings
Expression of Lex antigen in Schistosoma japonicum and S.haematobium and immune responses to Lex in infected animals: lack of Lex expression in other trematodes and nematodes.
Glycobiology 1998;8(6):615-24.
1998: W Liu; V Ramachandran; J Kang; T K Kishimoto; Richard D Cummings; Rodger P McEver
Identification of N-terminal residues on P-selectin glycoprotein ligand-1 required for binding to P-selectin.
The Journal of biological chemistry 1998;273(12):7078-87.
1997: Rodger P McEver; Richard D Cummings
Role of PSGL-1 binding to selectins in leukocyte recruitment.
The Journal of clinical investigation 1997;100(11 Suppl):S97-103.
1997: S K Cho; J C Yeh; Richard D Cummings
Secretion of alpha1,3-galactosyltransferase by cultured cells and presence of enzyme in animal sera.
Glycoconjugate journal 1997;14(7):809-19.
1997: Z Zheng; Richard D Cummings; P E Pummill; Paul W Kincade
Growth as a solid tumor or reduced glucose concentrations in culture reversibly induce CD44-mediated hyaluronan recognition by Chinese hamster ovary cells.
The Journal of clinical investigation 1997;100(5):1217-29.
1997: Rodger P McEver; Richard D Cummings
Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment.
The Journal of clinical investigation 1997;100(3):485-91.
1997: S K Cho; Richard D Cummings
A soluble form of alpha1,3-galactosyltransferase functions within cells to galactosylate glycoproteins.
The Journal of biological chemistry 1997;272(21):13622-8.
1997: J Yeh; Richard D Cummings
Differential recognition of glycoprotein acceptors by terminal glycosyltransferases.
Glycobiology 1997;7(2):241-51.
1997: A Kwame Nyame; JB Pilcher; Victor Tsang; Richard D Cummings
Rodents infected with Schistosoma mansoni produce cytolytic IgG and IgM antibodies to the Lewis x antigen.
Glycobiology 1997;7(2):207-15.
1997: K Y Do; S I Do; Richard D Cummings
Differential expression of LacdiNAc sequences (GalNAc beta 1-4GlcNAc-R) in glycoproteins synthesized by Chinese hamster ovary and human 293 cells.
Glycobiology 1997;7(2):183-94.
1997: P A Prieto; R D Larsen; Moonjae Cho; H N Rivera; Ali Shilatifard; J B Lowe; Richard D Cummings; David Smith
Expression of human H-type alpha1,2-fucosyltransferase encoding for blood group H(O) antigen in Chinese hamster ovary cells. Evidence for preferential fucosylation and truncation of polylactosamine sequences.
The Journal of biological chemistry 1997;272(4):2089-97.
1997: L Yan; P P Wilkins; G Alvarez-Manilla; S I Do; David Smith; Richard D Cummings
Immobilized Lotus tetragonolobus agglutinin binds oligosaccharides containing the Le(x) determinant.
Glycoconjugate journal 1997;14(1):45-55.
1997: K D White; Richard D Cummings; Frank J Waxman
Ig N-glycan orientation can influence interactions with the complement system.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):426-35.
1996: D Gupta; M Cho; Richard D Cummings; Curtis Brewer
Thermodynamics of carbohydrate binding to galectin-1 from Chinese hamster ovary cells and two mutants. A comparison with four galactose-specific plant lectins.
Biochemistry 1996;35(48):15236-43.
1996: S F Li; F A Neethling; S Taniguchi; J C Yeh; T Kobayashi; Y Ye; Eugen Koren; Richard D Cummings; David K C Cooper
Glycans derived from porcine stomach mucin are effective inhibitors of natural anti-alpha-galactosyl antibodies in vitro and after intravenous infusion in baboons.
Transplantation 1996;62(9):1324-31.
1996: RA Debose-Boyd; A Kwame Nyame; David Smith; Richard D Cummings
alpha1,4-Fucosyltransferase activity in human serum and saliva.
Archives of biochemistry and biophysics 1996;335(1):109-17.
1996: Zoltan G Laszik; P J Jansen; Richard D Cummings; T F Tedder; Rodger P McEver; Kevin L Moore
P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells.
Blood 1996;88(8):3010-21.
1996: M Cho; Richard D Cummings
Characterization of monomeric forms of galectin-1 generated by site-directed mutagenesis.
Biochemistry 1996;35(40):13081-8.
1996: P P Wilkins; Rodger P McEver; Richard D Cummings
Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells.
The Journal of biological chemistry 1996;271(31):18732-42.
1996: Richard D Cummings; A Kwame Nyame
Glycobiology of schistosomiasis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(8):838-48.
1996: J C Yeh; Richard D Cummings
Absorbance- and light-based solid-phase assays for CMPNeuAc:Galbeta1-4GlcNAc-R alpha-2,3-sialyltransferase.
Analytical biochemistry 1996;236(1):126-33.
1996: S Li; F A Neethling; J C Yeh; David K C Cooper; Richard D Cummings
Potent inhibition of human and baboon anti-alpha Gal antibodies by a subfraction of oligosaccharides derived from porcine stomach mucin.
Transplantation proceedings 1996;28(2):558.
1996: F Li; H P Erickson; Judith A James; Kevin L Moore; Richard D Cummings; Rodger P McEver
Visualization of P-selectin glycoprotein ligand-1 as a highly extended molecule and mapping of protein epitopes for monoclonal antibodies.
The Journal of biological chemistry 1996;271(11):6342-8.
1996: A Kwame Nyame; J B Pilcher; Victor Tsang; Richard D Cummings
Schistosoma mansoni infection in humans and primates induces cytolytic antibodies to surface Le(x) determinants on myeloid cells.
Experimental parasitology 1996;82(2):191-200.
1996: F Li; P P Wilkins; S Crawley; J Weinstein; Richard D Cummings; Rodger P McEver
Post-translational modifications of recombinant P-selectin glycoprotein ligand-1 required for binding to P- and E-selectin.
The Journal of biological chemistry 1996;271(6):3255-64.
1996: S K Cho; J Yeh; M Cho; Richard D Cummings
Transcriptional regulation of alpha1,3-galactosyltransferase in embryonal carcinoma cells by retinoic acid. Masking of Lewis X antigens by alpha-galactosylation.
The Journal of biological chemistry 1996;271(6):3238-46.
1996: RA Debose-Boyd; A Kwame Nyame; Richard D Cummings
Schistosoma mansoni: characterization of an alpha 1-3 fucosyltransferase in adult parasites.
Experimental parasitology 1996;82(1):1-10.
1995: P P Wilkins; Kevin L Moore; Rodger P McEver; Richard D Cummings
Tyrosine sulfation of P-selectin glycoprotein ligand-1 is required for high affinity binding to P-selectin.
The Journal of biological chemistry 1995;270(39):22677-80.
1995: C S Wang; Azar M Dashti; K W Jackson; J C Yeh; Richard D Cummings; Jordan Tang
Isolation and characterization of human milk bile salt-activated lipase C-tail fragment.
Biochemistry 1995;34(33):10639-44.
1995: K Y Do; S I Do; Richard D Cummings
Alpha-lactalbumin induces bovine milk beta 1,4-galactosyltransferase to utilize UDP-GalNAc.
The Journal of biological chemistry 1995;270(31):18447-51.
1995: Rodger P McEver; Kevin L Moore; Richard D Cummings
Leukocyte trafficking mediated by selectin-carbohydrate interactions.
The Journal of biological chemistry 1995;270(19):11025-8.
1995: Ali Shilatifard; Richard D Cummings
Sulphate release from keratan sulphate and heparan sulphate by bovine N-acetylglucosamine-6-sulphate sulphatase.
Glycobiology 1995;5(3):291-7.
1995: M Cho; Richard D Cummings
Galectin-1, a beta-galactoside-binding lectin in Chinese hamster ovary cells. II. Localization and biosynthesis.
The Journal of biological chemistry 1995;270(10):5207-12.
1995: M Cho; Richard D Cummings
Galectin-1, a beta-galactoside-binding lectin in Chinese hamster ovary cells. I. Physical and chemical characterization.
The Journal of biological chemistry 1995;270(10):5198-206.
1995: Kevin L Moore; Kamala D Patel; R E Bruehl; F Li; D A Johnson; H S Lichenstein; Richard D Cummings; DF Bainton; Rodger P McEver
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin.
The Journal of cell biology 1995;128(4):661-71.
1994: J Srivatsan; David Smith; Richard D Cummings
Demonstration of a novel UDPGalNAc:GlcNAc beta 1-4 N-acetylgalactosaminyltransferase in extracts of Schistosoma mansoni.
The Journal of parasitology 1994;80(6):884-90.
1994: L Yan; David Smith; Richard D Cummings
Determination of GDP-Fuc:Gal beta 1-4GlcNAc-R (Fuc to GlcNAc) alpha 1,3 fucosyltransferase activity by a solid-phase method.
Analytical biochemistry 1994;223(1):111-8.
1994: K Y Do; Nevis Fregien; James Michael Pierce; Richard D Cummings
Modification of glycoproteins by N-acetylglucosaminyltransferase V is greatly influenced by accessibility of the enzyme to oligosaccharide acceptors.
The Journal of biological chemistry 1994;269(38):23456-64.
1994: Kevin L Moore; S F Eaton; D E Lyons; H S Lichenstein; Richard D Cummings; Rodger P McEver
The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine.
The Journal of biological chemistry 1994;269(37):23318-27.
1994: M J Cho; Richard D Cummings
Structure and biosynthesis of carbohydrate ligands for animal lectins involved in cell adhesion.
Biochemical Society transactions 1994;22(2):378-81.
1994: Ali Shilatifard; Richard D Cummings
Purification and characterization of N-acetylglucosamine-6-sulfate sulfatase from bovine kidney: evidence for the presence of a novel endosulfatase activity.
Biochemistry 1994;33(14):4273-82.
1994: SH Barondes; V Castronovo; Douglas N W Cooper; Richard D Cummings; K Drickamer; T Feizi; M A Gitt; J Hirabayashi; C Hughes; K Kasai
Galectins: a family of animal beta-galactoside-binding lectins.
Cell 1994;76(4):597-8.
1994: Richard D Cummings
Use of lectins in analysis of glycoconjugates.
Methods in enzymology 1994;230():66-86.
1993: S Kang; Richard D Cummings; J W McCall
Characterization of the N-linked oligosaccharides in glycoproteins synthesized by microfilariae of Dirofilaria immitis.
The Journal of parasitology 1993;79(6):815-28.
1993: N L Stults; Richard D Cummings
O-linked fucose in glycoproteins from Chinese hamster ovary cells.
Glycobiology 1993;3(6):589-96.
1993: J C Yeh; J R Seals; CI Murphy; H van Halbeek; Richard D Cummings
Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.
Biochemistry 1993;32(41):11087-99.
1993: K Y Do; Richard D Cummings
2,6-branched mannose and the regulation of poly-N-acetyllactosamine biosynthesis in N-linked oligosaccharides of Chinese hamster ovary cells.
The Journal of biological chemistry 1993;268(29):22028-35.
1993: K E Norgard; Kevin L Moore; S Diaz; N L Stults; S Ushiyama; Rodger P McEver; Richard D Cummings; Ajit Varki
Characterization of a specific ligand for P-selectin on myeloid cells. A minor glycoprotein with sialylated O-linked oligosaccharides.
The Journal of biological chemistry 1993;268(17):12764-74.
1993: Ali Shilatifard; R K Merkle; D E Helland; J L Welles; W A Haseltine; Richard D Cummings
Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine.
Journal of virology 1993;67(2):943-52.
1993: Q Zhou; Richard D Cummings
L-14 lectin recognition of laminin and its promotion of in vitro cell adhesion.
Archives of biochemistry and biophysics 1993;300(1):6-17.
1992: Richard D Cummings; David Smith
The selectin family of carbohydrate-binding proteins: structure and importance of carbohydrate ligands for cell adhesion.
BioEssays : news and reviews in molecular, cellular and developmental biology 1992;14(12):849-56.
1992: S Mattox; K Walrath; D Ceiler; David Smith; Richard D Cummings
A solid-phase assay for the activity of CMPNeuAc:Gal beta 1-4GlcNAc-R alpha-2,6-sialyltransferase.
Analytical biochemistry 1992;206(2):430-6.
1992: J Srivatsan; David Smith; Richard D Cummings
The human blood fluke Schistosoma mansoni synthesizes glycoproteins containing the Lewis X antigen.
The Journal of biological chemistry 1992;267(28):20196-203.
1992: J Srivatsan; David Smith; Richard D Cummings
Schistosoma mansoni synthesizes novel biantennary Asn-linked oligosaccharides containing terminal beta-linked N-acetylgalactosamine.
Glycobiology 1992;2(5):445-52.
1992: S I Do; Richard D Cummings
Presence of O-linked oligosaccharide on a threonine residue in the human transferrin receptor.
Glycobiology 1992;2(4):345-53.
1992: Kevin L Moore; N L Stults; S Diaz; David Smith; Richard D Cummings; Ajit Varki; Rodger P McEver
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.
The Journal of cell biology 1992;118(2):445-56.
1992: S I Do; Richard D Cummings
The hamster transferrin receptor contains Ser/Thr-linked oligosaccharides: use of a lectin-resistant CHO cell line to identify glycoproteins containing these linkages.
Journal of biochemical and biophysical methods 1992;24(3-4):153-65.
1992: N L Stults; N F Stocks; H Rivera; J Gray; Richard O McCann; D O'Kane; Richard D Cummings; M J Cormier; David Smith
Use of recombinant biotinylated aequorin in microtiter and membrane-based assays: purification of recombinant apoaequorin from Escherichia coli.
Biochemistry 1992;31(5):1433-42.
1992: C K Makaaru; R T Damian; David Smith; Richard D Cummings
The human blood fluke Schistosoma mansoni synthesizes a novel type of glycosphingolipid.
The Journal of biological chemistry 1992;267(4):2251-7.
1991: R K Merkle; D E Helland; J L Welles; Ali Shilatifard; W A Haseltine; Richard D Cummings
gp160 of HIV-I synthesized by persistently infected Molt-3 cells is terminally glycosylated: evidence that cleavage of gp160 occurs subsequent to oligosaccharide processing.
Archives of biochemistry and biophysics 1991;290(1):248-57.
1991: Q Zhou; K L Moore; David Smith; A Varki; R P McEver; Richard D Cummings
The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.
The Journal of cell biology 1991;115(2):557-64.
1991: G F Clark; C M Gorbea; Richard D Cummings; S Mattox; David Smith
Decreased biosynthesis of Forssman glycolipid after retinoic acid-induced differentiation of mouse F9 teratocarcinoma cells. Lectin-affinity chromatography of the glycolipid-derived oligosaccharide.
Carbohydrate research 1991;213():155-68.
1991: P F Zatta; K Nyame; M J Cormier; S A Mattox; P A Prieto; David Smith; Richard D Cummings
A solid-phase assay for beta-1,4-galactosyltransferase activity in human serum using recombinant aequorin.
Analytical biochemistry 1991;194(1):185-91.
1991: T Seguchi; R K Merkle; M Ono; Michihiko Kuwano; Richard D Cummings
The dysfunctional LDL receptor in a monensin-resistant mutant of Chinese hamster ovary cells lacks selected O-linked oligosaccharides.
Archives of biochemistry and biophysics 1991;284(2):245-56.
1990: K Y Do; David Smith; Richard D Cummings
LAMP-1 in CHO cells is a primary carrier of poly-N-acetyllactosamine chains and is bound preferentially by a mammalian S-type lectin.
Biochemical and biophysical research communications 1990;173(3):1123-8.
1990: C A Rivera-Marrero; Richard D Cummings
Schistosoma mansoni contains a galactosyltransferase activity distinct from that typically found in mammalian cells.
Molecular and biochemical parasitology 1990;43(1):59-67.
1990: Q Zhou; Richard D Cummings
The S-type lectin from calf heart tissue binds selectively to the carbohydrate chains of laminin.
Archives of biochemistry and biophysics 1990;281(1):27-35.
1990: R D Larsen; C A Rivera-Marrero; L K Ernst; Richard D Cummings; John B Lowe
Frameshift and nonsense mutations in a human genomic sequence homologous to a murine UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase cDNA.
The Journal of biological chemistry 1990;265(12):7055-61.
1990: David Smith; R D Larsen; S Mattox; J B Lowe; Richard D Cummings
Transfer and expression of a murine UDP-Gal:beta-D-Gal-alpha 1,3-galactosyltransferase gene in transfected Chinese hamster ovary cells. Competition reactions between the alpha 1,3-galactosyltransferase and the endogenous alpha 2,3-sialyltransferase.
The Journal of biological chemistry 1990;265(11):6225-34.
1990: S I Do; Caroline A Enns; Richard D Cummings
Human transferrin receptor contains O-linked oligosaccharides.
The Journal of biological chemistry 1990;265(1):114-25.
1989: N L Stults; Marcus Fechheimer; Richard D Cummings
Relationship between Golgi architecture and glycoprotein biosynthesis and transport in Chinese hamster ovary cells.
The Journal of biological chemistry 1989;264(33):19956-66.
1989: R K Merkle; Q Zhou; T K Schultz; W B Harper; Richard D Cummings
Characterization of an S-type lectin purified from porcine heart.
Archives of biochemistry and biophysics 1989;274(2):404-16.
1989: R D Larsen; V P Rajan; M M Ruff; Jolanta F Kukowska-Latallo; Richard D Cummings; John B Lowe
Isolation of a cDNA encoding a murine UDPgalactose:beta-D-galactosyl- 1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase: expression cloning by gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8227-31.
1989: K Nyame; David Smith; R T Damian; Richard D Cummings
Complex-type asparagine-linked oligosaccharides in glycoproteins synthesized by Schistosoma mansoni adult males contain terminal beta-linked N-acetylgalactosamine.
The Journal of biological chemistry 1989;264(6):3235-43.
1989: Richard D Cummings; R K Merkle; N L Stults
Separation and analysis of glycoprotein oligosaccharides.
Methods in cell biology 1989;32():141-83.
1988: W C Wang; G F Clark; David Smith; Richard D Cummings
Separation of oligosaccharides containing terminal alpha-linked galactose residues by affinity chromatography on Griffonia simplicifolia I bound to concanavalin A-sepharose.
Analytical biochemistry 1988;175(2):390-6.
1988: R K Merkle; Richard D Cummings
Asparagine-linked oligosaccharides containing poly-N-acetyllactosamine chains are preferentially bound by immobilized calf heart agglutinin.
The Journal of biological chemistry 1988;263(31):16143-9.
1988: K Nyame; Richard D Cummings; R T Damian
Characterization of the N- and O-linked oligosaccharides in glycoproteins synthesized by Schistosoma mansoni schistosomula.
The Journal of parasitology 1988;74(4):562-72.
1988: R K Pathak; R K Merkle; Richard D Cummings; Joseph L Goldstein; Michael S Brown; Richard G W Anderson
Immunocytochemical localization of mutant low density lipoprotein receptors that fail to reach the Golgi complex.
The Journal of cell biology 1988;106(6):1831-41.
1988: W C Wang; Richard D Cummings
The immobilized leukoagglutinin from the seeds of Maackia amurensis binds with high affinity to complex-type Asn-linked oligosaccharides containing terminal sialic acid-linked alpha-2,3 to penultimate galactose residues.
The Journal of biological chemistry 1988;263(10):4576-85.
1988: K Nyame; Richard D Cummings; R T Damian
Characterization of the high mannose asparagine-linked oligosaccharides synthesized by Schistosoma mansoni adult male worms.
Molecular and biochemical parasitology 1988;28(3):265-74.
1988: Richard D Cummings; S A Mattox
Retinoic acid-induced differentiation of the mouse teratocarcinoma cell line F9 is accompanied by an increase in the activity of UDP-galactose: beta-D-galactosyl-alpha 1,3-galactosyltransferase.
The Journal of biological chemistry 1988;263(1):511-9.
1987: R K Merkle; Richard D Cummings
Relationship of the terminal sequences to the length of poly-N-acetyllactosamine chains in asparagine-linked oligosaccharides from the mouse lymphoma cell line BW5147. Immobilized tomato lectin interacts with high affinity with glycopeptides containing long poly-N-acetyllactosamine chains.
The Journal of biological chemistry 1987;262(17):8179-89.
1987: K Nyame; Richard D Cummings; R T Damian
Schistosoma mansoni synthesizes glycoproteins containing terminal O-linked N-acetylglucosamine residues.
The Journal of biological chemistry 1987;262(17):7990-5.
1987: W C Wang; Richard D Cummings
An assay for leukoagglutinating lectins using suspension cultured mouse lymphoma cells (BW5147) stained with neutral red.
Analytical biochemistry 1987;161(1):80-4.
1987: R K Merkle; Richard D Cummings
Lectin affinity chromatography of glycopeptides.
Methods in enzymology 1987;138():232-59.
1985: Richard D Cummings; A M Soderquist; G Carpenter
The oligosaccharide moieties of the epidermal growth factor receptor in A-431 cells. Presence of complex-type N-linked chains that contain terminal N-acetylgalactosamine residues.
The Journal of biological chemistry 1985;260(22):11944-52.
1984: Richard D Cummings; S Kornfeld
The distribution of repeating [Gal beta 1,4GlcNAc beta 1,3] sequences in asparagine-linked oligosaccharides of the mouse lymphoma cell lines BW5147 and PHAR 2.1.
The Journal of biological chemistry 1984;259(10):6253-60.
1983: Richard D Cummings; S Kornfeld; W J Schneider; K K Hobgood; H Tolleshaug; Michael S Brown; Joseph L Goldstein
Biosynthesis of N- and O-linked oligosaccharides of the low density lipoprotein receptor.
The Journal of biological chemistry 1983;258(24):15261-73.
1983: L Liscum; Richard D Cummings; R G Anderson; G N DeMartino; Joseph L Goldstein; Michael S Brown
3-Hydroxy-3-methylglutaryl-CoA reductase: a transmembrane glycoprotein of the endoplasmic reticulum with N-linked "high-mannose" oligosaccharides.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(23):7165-9.
1980: James Michael Pierce; Richard D Cummings; S Roth
The localization of galactosyltransferases in polyacrylamide gels by a coupled enzyme assay.
Analytical biochemistry 1980;102(2):441-9.
1979: Richard D Cummings; Thomas Cebula; S Roth
Characterization of a galactosyltransferase in plasma membrane-enriched fractions from Balb/c 3T12 cells.
The Journal of biological chemistry 1979;254(4):1233-40.