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Kenneth Cundy

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Concepts & Ideas

Procedures

Living Beings

Disorders

HIV Infections

Anatomy

Kidney

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Co-Publications
Name
17
Lee, William
11
Shaw, JP
6
Eisenberg, Eugene
5
Bidgood, AM
5
Bischofberger, Norbert
5
Jaffe, HS
5
Lietman, Paul
4
Barditch-Crovo, Patricia
3
Arimilli, MN
3
Chen, MS
3
Petty, Brent
3
Kim, Choung
3
Toole, J
2
Visor, GC
2
Lalezari, Jacob

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Publications

TOP 3
Lee William A; He Gong-Xin; Eisenberg Eugene; Cihlar Tomas; Swaminathan Swami; Mulato Andrew; Cundy Kenneth C
Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue.
Cullen J M; Li D H; Brown C; Eisenberg E J; Cundy K C; Wolfe J; Toole J; Gibbs C
Antiviral efficacy and pharmacokinetics of oral adefovir dipivoxil in chronically woodchuck hepatitis virus-infected woodchucks.
Sweeny D J; Lynch G; Bidgood A M; Lew W; Wang K Y; Cundy K C
Metabolism of the influenza neuraminidase inhibitor prodrug oseltamivir in the rat.

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All Publications

2005: Lee William A; He Gong-Xin; Eisenberg Eugene; Cihlar Tomas; Swaminathan Swami; Mulato Andrew; Cundy Kenneth C
Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue.
Antimicrobial agents and chemotherapy 2005;49(5):1898-906.
2001: Cullen J M; Li D H; Brown C; Eisenberg E J; Cundy K C; Wolfe J; Toole J; Gibbs C
Antiviral efficacy and pharmacokinetics of oral adefovir dipivoxil in chronically woodchuck hepatitis virus-infected woodchucks.
Antimicrobial agents and chemotherapy 2001;45(10):2740-5.
2000: Sweeny D J; Lynch G; Bidgood A M; Lew W; Wang K Y; Cundy K C
Metabolism of the influenza neuraminidase inhibitor prodrug oseltamivir in the rat.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(7):737-41.
1999: Oliyai R; Shaw J P; Sueoka-Lennen C M; Cundy K C; Arimilli M N; Jones R J; Lee W A
Aryl ester prodrugs of cyclic HPMPC. I: Physicochemical characterization and in vitro biological stability.
Pharmaceutical research 1999;16(11):1687-93.
1999: Tarantal A F; Marthas M L; Shaw J P; Cundy K; Bischofberger N
Administration of 9-[2-(R)-(phosphonomethoxy)propyl]adenine (PMPA) to gravid and infant rhesus macaques (Macaca mulatta): safety and efficacy studies.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1999;20(4):323-33.
1999: Cundy K C
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir.
Clinical pharmacokinetics 1999;36(2):127-43.
1999: Cundy K C; Barditch-Crovo P; Petty B G; Ruby A; Redpath M; Jaffe H S; Lietman P S
Clinical pharmacokinetics of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine in human immunodeficiency virus-infected patients.
Antimicrobial agents and chemotherapy 1999;43(2):271-7.
1999: Brody S R; Humphreys M H; Gambertoglio J G; Schoenfeld P; Cundy K C; Aweeka F T
Pharmacokinetics of cidofovir in renal insufficiency and in continuous ambulatory peritoneal dialysis or high-flux hemodialysis.
Clinical pharmacology and therapeutics 1999;65(1):21-8.
1998: Eisenberg E J; Cundy K C
High-performance liquid chromatographic determination of GS4071, a potent inhibitor of influenza neuraminidase, in plasma by precolumn fluorescence derivatization with naphthalenedialdehyde.
Journal of chromatography. B, Biomedical sciences and applications 1998;716(1-2):267-73.
1998: Deeks S G; Barditch-Crovo P; Lietman P S; Hwang F; Cundy K C; Rooney J F; Hellmann N S; Safrin S; Kahn J O
Safety, pharmacokinetics, and antiretroviral activity of intravenous 9-[2-(R)-(Phosphonomethoxy)propyl]adenine, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults.
Antimicrobial agents and chemotherapy 1998;42(9):2380-4.
1998: Lacy S A; Hitchcock M J; Lee W A; Tellier P; Cundy K C
Effect of oral probenecid coadministration on the chronic toxicity and pharmacokinetics of intravenous cidofovir in cynomolgus monkeys.
Toxicological sciences : an official journal of the Society of Toxicology 1998;44(2):97-106.
1998: Van Rompay K K; Marthas M L; Lifson J D; Berardi C J; Vasquez G M; Agatep E; Dehqanzada Z A; Cundy K C; Bischofberger N; Pedersen N C
Administration of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaques.
AIDS research and human retroviruses 1998;14(9):761-73.
1998: Eisenberg E J; Lynch G R; Bidgood A M; Krishnamurty K; Cundy K C
Isolation and identification of a metabolite of cidofovir from rat kidney.
Journal of pharmaceutical and biomedical analysis 1998;16(8):1349-56.
1998: Cundy K C; Sueoka C; Lynch G R; Griffin L; Lee W A; Shaw J P
Pharmacokinetics and bioavailability of the anti-human immunodeficiency virus nucleotide analog 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs.
Antimicrobial agents and chemotherapy 1998;42(3):687-90.
1998: Li W; Escarpe P A; Eisenberg E J; Cundy K C; Sweet C; Jakeman K J; Merson J; Lew W; Williams M; Zhang L; Kim C U; Bischofberger N; Chen M S; Mendel D B
Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071.
Antimicrobial agents and chemotherapy 1998;42(3):647-53.
1997: Shaw J P; Sueoko C M; Oliyai R; Lee W A; Arimilli M N; Kim C U; Cundy K C
Metabolism and pharmacokinetics of novel oral prodrugs of 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs.
Pharmaceutical research 1997;14(12):1824-9.
1997: Cundy K C; Sue I L; Visor G C; Marshburn J; Nakamura C; Lee W A; Shaw J P
Oral formulations of adefovir dipivoxil: in vitro dissolution and in vivo bioavailability in dogs.
Journal of pharmaceutical sciences 1997;86(12):1334-8.
1997: Eisenberg E J; Bidgood A; Cundy K C
Penetration of GS4071, a novel influenza neuraminidase inhibitor, into rat bronchoalveolar lining fluid following oral administration of the prodrug GS4104.
Antimicrobial agents and chemotherapy 1997;41(9):1949-52.
1997: Barditch-Crovo P; Toole J; Hendrix C W; Cundy K C; Ebeling D; Jaffe H S; Lietman P S
Anti-human immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adefovir dipivoxil (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethoxyethyl]adenine) in HIV-infected patients.
The Journal of infectious diseases 1997;176(2):406-13.
1997: Cundy K C; Lynch G; Lee W A
Bioavailability and metabolism of cidofovir following topical administration to rabbits.
Antiviral research 1997;35(2):113-22.
1997: Shaw J P; Louie M S; Krishnamurthy V V; Arimilli M N; Jones R J; Bidgood A M; Lee W A; Cundy K C
Pharmacokinetics and metabolism of selected prodrugs of PMEA in rats.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(3):362-6.
1996: Kim C U; McGee L R; Krawczyk S H; Harwood E; Harada Y; Swaminathan S; Bischofberger N; Chen M S; Cherrington J M; Xiong S F; Griffin L; Cundy K C; Lee A; Yu B; Gulnik S; Erickson J W
New series of potent, orally bioavailable, non-peptidic cyclic sulfones as HIV-1 protease inhibitors.
Journal of medicinal chemistry 1996;39(18):3431-4.
1996: Cundy K C; Bidgood A M; Lynch G; Shaw J P; Griffin L; Lee W A
Pharmacokinetics, bioavailability, metabolism, and tissue distribution of cidofovir (HPMPC) and cyclic HPMPC in rats.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(7):745-52.
1996: Cundy K C; Li Z H; Hitchcock M J; Lee W A
Pharmacokinetics of cidofovir in monkeys. Evidence for a prolonged elimination phase representing phosphorylated drug.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(7):738-44.
1996: Cundy K C; Lynch G; Shaw J P; Hitchcock M J; Lee W A
Distribution and metabolism of intravitreal cidofovir and cyclic HPMPC in rabbits.
Current eye research 1996;15(5):569-76.
1996: Eisenberg E J; Cundy K C
High-performance liquid chromatographic determination of cytosine-containing compounds by precolumn fluorescence derivatization with phenacyl bromide: application to antiviral nucleosides and nucleotides.
Journal of chromatography. B, Biomedical applications 1996;679(1-2):119-27.
1996: Cundy K C; Li Z H; Lee W A
Effect of probenecid on the distribution, metabolism, and excretion of cidofovir in rabbits.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(3):315-21.
1996: Wachsman M; Petty B G; Cundy K C; Jaffe H S; Fisher P E; Pastelak A; Lietman P S
Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects.
Antiviral research 1996;29(2-3):153-61.
1995: Lee W A; Fishback J A; Shaw J P; Bock L C; Griffin L C; Cundy K C
A novel oligodeoxynucleotide inhibitor of thrombin. II. Pharmacokinetics in the cynomolgus monkey.
Pharmaceutical research 1995;12(12):1943-7.
1995: Shaw J P; Fishback J A; Cundy K C; Lee W A
A novel oligodeoxynucleotide inhibitor of thrombin. I. In vitro metabolic stability in plasma and serum.
Pharmaceutical research 1995;12(12):1937-42.
1995: Cundy K C; Barditch-Crovo P; Walker R E; Collier A C; Ebeling D; Toole J; Jaffe H S
Clinical pharmacokinetics of adefovir in human immunodeficiency virus type 1-infected patients.
Antimicrobial agents and chemotherapy 1995;39(11):2401-5.
1995: Cundy K C; Petty B G; Flaherty J; Fisher P E; Polis M A; Wachsman M; Lietman P S; Lalezari J P; Hitchcock M J; Jaffe H S
Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients.
Antimicrobial agents and chemotherapy 1995;39(6):1247-52.
1995: Lalezari J P; Drew W L; Glutzer E; James C; Miner D; Flaherty J; Fisher P E; Cundy K; Hannigan J; Martin J C
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue.
The Journal of infectious diseases 1995;171(4):788-96.
1994: Bischofberger N; Hitchcock M J; Chen M S; Barkhimer D B; Cundy K C; Kent K M; Lacy S A; Lee W A; Li Z H; Mendel D B
1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo.
Antimicrobial agents and chemotherapy 1994;38(10):2387-91.
1994: Cundy K C; Fishback J A; Shaw J P; Lee M L; Soike K F; Visor G C; Lee W A
Oral bioavailability of the antiretroviral agent 9-(2-phosphonylmethoxyethyl)adenine (PMEA) from three formulations of the prodrug bis(pivaloyloxymethyl)-PMEA in fasted male cynomolgus monkeys.
Pharmaceutical research 1994;11(6):839-43.
1994: Cundy K C; Shaw J P; Lee W A
Oral, subcutaneous, and intramuscular bioavailabilities of the antiviral nucleotide analog 9-(2-phosphonylmethoxyethyl) adenine in cynomolgus monkeys.
Antimicrobial agents and chemotherapy 1994;38(2):365-8.
1993: Eisenberg E J; Conzentino P; Eickhoff W M; Cundy K C
Pharmacokinetic measurement of drugs in lung epithelial lining fluid by microdialysis: aminoglycoside antibiotics in rat bronchi.
Journal of pharmacological and toxicological methods 1993;29(2):93-8.
1991: Eisenberg E J; Conzentino P; Liversidge G G; Cundy K C
Determination of allopurinol and oxypurinol in rat plasma, intestinal wash, and bile by high-performance liquid chromatography with electrochemical detection (HPLC/EC) following automated solid phase extraction.
Pharmaceutical research 1991;8(5):653-5.
1990: Eisenberg E J; Conzentino P; Liversidge G G; Cundy K C
Simultaneous determination of allopurinol and oxypurinol by liquid chromatography using immobilized xanthine oxidase with electrochemical detection.
Journal of chromatography 1990;530(1):65-73.

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