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David Curiel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Anatomy

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Gene Transfer Techniques

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Ovarian Neoplasms

Physiology

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Publications

TOP 3
van de Ven Rieneke; Lindenberg Jelle J; Oosterhoff Dinja; van den Tol M Petrousjka; Rosalia Rodney A; Murakami Miho; Everts Maaike; Scheffer George L; Scheper Rik J; de Gruijl Tanja D; Curiel David T
Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3.
Thacker Erin E; Nakayama Masaharu; Smith Bruce F; Bird R Curtis; Muminova Zhanat; Strong Theresa V; Timares Laura; Korokhov Nikolay; O'Neill Ann Marie; de Gruijl Tanja D; Glasgow Joel N; Tani Kenzaburo; Curiel David T
A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo.
Nelson Amy R; Davydova Julia; Curiel David T; Yamamoto Masato
Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer.

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All Publications

2009: van de Ven Rieneke; Lindenberg Jelle J; Oosterhoff Dinja; van den Tol M Petrousjka; Rosalia Rodney A; Murakami Miho; Everts Maaike; Scheffer George L; Scheper Rik J; de Gruijl Tanja D; Curiel David T
Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(9):895-906.
2009: Thacker Erin E; Nakayama Masaharu; Smith Bruce F; Bird R Curtis; Muminova Zhanat; Strong Theresa V; Timares Laura; Korokhov Nikolay; O'Neill Ann Marie; de Gruijl Tanja D; Glasgow Joel N; Tani Kenzaburo; Curiel David T
A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo.
Vaccine 2009;27(50):7116-24.
2009: Nelson Amy R; Davydova Julia; Curiel David T; Yamamoto Masato
Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer.
Cancer science 2009;100(11):2181-7.
2009: Kimball Kristopher J; Rivera Angel A; Zinn Kurt R; Icyuz Mert; Saini Vaibhav; Li Jing; Zhu Zeng B; Siegal Gene P; Douglas Joanne T; Curiel David T; Alvarez Ronald D; Borovjagin Anton V
Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.
Molecular imaging : official journal of the Society for Molecular Imaging 2009;8(5):264-77.
2009: Pérez-Berná Ana J; Marabini Roberto; Scheres Sjors H W; Menéndez-Conejero Rosa; Dmitriev Igor P; Curiel David T; Mangel Walter F; Flint S Jane; San Martín Carmen
Structure and uncoating of immature adenovirus.
Journal of molecular biology 2009;392(2):547-57.
2009: Short Joshua J; Curiel David T
Oncolytic adenoviruses targeted to cancer stem cells.
Molecular cancer therapeutics 2009;8(8):2096-102.
2009: Matthews Kellie S; Alvarez Ronald D; Curiel David T
Advancements in adenoviral based virotherapy for ovarian cancer.
Advanced drug delivery reviews 2009;61(10):836-41.
2009: Matthews Kellie; Noker Patricia E; Tian Baohong; Grimes Sheila D; Fulton Ronna; Schweikart Karen; Harris Raymond; Aurigemma Rose; Wang Minghui; Barnes Mack N; Siegal Gene P; Hemminki Akseli; Zinn Kurt; Curiel David T; Alvarez Ronald D
Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4131-7.
2009: Dent Paul; Curiel David T; Fisher Paul B; Grant Steven
Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2009;12(3):65-73.
2009: Kashentseva Elena A; Douglas Joanne T; Zinn Kurt R; Curiel David T; Dmitriev Igor P
Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody.
Journal of molecular biology 2009;388(3):443-61.
2009: Stoff Alexander; Rivera Angel A; Sanjib Banerjee N; Moore Steven T; Michael Numnum T; Espinosa-de-Los-Monteros Antonio; Richter Dirk F; Siegal Gene P; Chow Louise T; Feldman Dale; Vasconez Luis O; Michael Mathis J; Stoff-Khalili Mariam A; Curiel David T
Promotion of incisional wound repair by human mesenchymal stem cell transplantation.
Experimental dermatology 2009;18(4):362-9.
2009: Li Hua-Jung; Everts Maaike; Yamamoto Masato; Curiel David T; Herschman Harvey R
Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors.
Cancer research 2009;69(2):554-64.
2009: Dent Paul; Grant Steven; Fisher Paul B; Curiel David T
PI3K: A rational target for ovarian cancer therapy?
Cancer biology & therapy 2009;8(1):27-30.
2008: San Martín Carmen; Glasgow Joel N; Borovjagin Anton; Beatty Matthew S; Kashentseva Elena A; Curiel David T; Marabini Roberto; Dmitriev Igor P
Localization of the N-terminus of minor coat protein IIIa in the adenovirus capsid.
Journal of molecular biology 2008;383(4):923-34.
2008: Park Margaret A; Zhang Guo; Mitchell Clint; Rahmani Mohamed; Hamed Hossein; Hagan Michael P; Yacoub Adly; Curiel David T; Fisher Paul B; Grant Steven; Dent Paul
Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
Molecular cancer therapeutics 2008;7(9):2633-48.
2008: Zhang Guo; Park Margaret A; Mitchell Clint; Hamed Hossein; Rahmani Mohamed; Martin Aditi Pandya; Curiel David T; Yacoub Adly; Graf Martin; Lee Ray; Roberts John D; Fisher Paul B; Grant Steven; Dent Paul
Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(17):5385-99.
2008: Dent Paul; Yacoub Adly; Park Margaret; Sarkar Devanand; Shah Khalid; Curiel David T; Grant Steven; Fisher Paul B
Searching for a cure: gene therapy for glioblastoma.
Cancer biology & therapy 2008;7(9):1335-40.
2008: van de Ven Rieneke; Scheffer George L; Reurs Anneke W; Lindenberg Jelle J; Oerlemans Ruud; Jansen Gerrit; Gillet Jean-Pierre; Glasgow Joel N; Pereboev Alexander; Curiel David T; Scheper Rik J; de Gruijl Tanja D
A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration.
Blood 2008;112(6):2353-9.
2008: Othman Essam-Eldin R; Zhu Zeng B; Curiel David T; Khatoon Nilufar; Salem Hosam T; Khalifa Essam Al-Din M; Al-Hendy Ayman
Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells.
American journal of obstetrics and gynecology 2008;199(2):117.e1-6.
2008: Tang Yizhe; Le Long P; Matthews Qiana L; Han Tie; Wu Hongju; Curiel David T
Derivation of a triple mosaic adenovirus based on modification of the minor capsid protein IX.
Virology 2008;377(2):391-400.
2008: Chen Jian; Wang John; Li Jun; Wu Qi; Chu Lim Fei; Yang Pingar; Hsu Hui-Chen; Curiel David T; Mountz John D
Enhancement of cytotoxic T-lymphocyte response in aged mice by a novel treatment with recombinant AdIL-12 and wild-type adenovirus in rapid succession.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1500-6.
2008: Sekine Shinichi; Kataoka Kosuke; Fukuyama Yoshiko; Adachi Yasuo; Davydova Julia; Yamamoto Masato; Kobayashi Ryoki; Fujihashi Keiko; Suzuki Hideaki; Curiel David T; Shizukuishi Satoshi; McGhee Jerry R; Fujihashi Kohtaro
A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8126-34.
2008: Tsuruta Yuko; Pereboeva Larisa; Breidenbach Martina; Rein Daniel T; Wang Minghui; Alvarez Ronald D; Siegal Gene P; Dent Paul; Fisher Paul B; Curiel David T
A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3582-8.
2008: Zhu Zeng B; Lu Baogen; Park Miey; Makhija Sharmila K; Numnum Thomas M; Kendrick James E; Wang Minghui; Tsuruta Yuko; Fisher Paul; Alvarez Ronald D; Zhou Fen; Siegal Gene P; Wu Hongju; Curiel David T
Development of an optimized conditionally replicative adenoviral agent for ovarian cancer.
International journal of oncology 2008;32(6):1179-88.
2008: Bird R Curtis; Deinnocentes Patricia; Lenz Steven; Thacker Erin E; Curiel David T; Smith Bruce F
An allogeneic hybrid-cell fusion vaccine against canine mammary cancer.
Veterinary immunology and immunopathology 2008;123(3-4):289-304.
2008: Yacoub Adly; Hamed Hossein; Emdad Luni; Dos Santos Wagner; Gupta Pankaj; Broaddus William C; Ramakrishnan Viswanathan; Sarkar Devanand; Shah Khalid; Curiel David T; Grant Steven; Fisher Paul B; Dent Paul
MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors.
Cancer biology & therapy 2008;7(6):917-33.
2008: Gupta Pankaj; Emdad Luni; Lebedeva Irina V; Sarkar Devanand; Dent Paul; Curiel David T; Settleman Jeffrey; Fisher Paul B
Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva.
Journal of cellular physiology 2008;215(3):827-36.
2008: Paul C P L; Everts M; Glasgow J N; Dent P; Fisher P B; Ulasov I V; Lesniak M S; Stoff-Khalili M A; Roth J C; Preuss M A; Dirven C M F; Lamfers M L M; Siegal G P; Zhu Z B; Curiel D T
Characterization of infectivity of knob-modified adenoviral vectors in glioma.
Cancer biology & therapy 2008;7(5):786-93.
2008: Roth J C; Curiel D T; Pereboeva L
Cell vehicle targeting strategies.
Gene therapy 2008;15(10):716-29.
2008: Sarkar D; Su Z-Z; Park E-S; Vozhilla N; Dent P; Curiel D T; Fisher P B
A cancer terminator virus eradicates both primary and distant human melanomas.
Cancer gene therapy 2008;15(5):293-302.
2008: Park Margaret A; Yacoub Adly; Sarkar Devanand; Emdad Luni; Rahmani Mohammed; Spiegel Sarah; Koumenis Costas; Graf Martin; Curiel David T; Grant Steven; Fisher Paul B; Dent Paul
PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells.
Autophagy 2008;4(4):513-5.
2008: Ramírez Pedro J; Vickers Selwyn M; Ono Hidetaka A; Davydova Julia; Takayama Koichi; Thompson Timothy C; Curiel David T; Bland Kirby I; Yamamoto Masato
Optimization of conditionally replicative adenovirus for pancreatic cancer and its evaluation in an orthotopic murine xenograft model.
American journal of surgery 2008;195(4):481-90.
2008: Park Margaret A; Curiel David T; Koumenis Costas; Graf Martin; Chen Ching-Shih; Fisher Paul B; Grant Steven; Dent Paul
PERK-dependent regulation of HSP70 expression and the regulation of autophagy.
Autophagy 2008;4(3):364-7.
2008: Schoehn Guy; El Bakkouri Majida; Fabry Céline M S; Billet Oliver; Estrozi Leandro F; Le Long; Curiel David T; Kajava Andrey V; Ruigrok Rob W H; Kremer Eric J
Three-dimensional structure of canine adenovirus serotype 2 capsid.
Journal of virology 2008;82(7):3192-203.
2008: Park Margaret A; Yacoub Adly; Rahmani Mohammed; Zhang Guo; Hart Lori; Hagan Michael P; Calderwood Stuart K; Sherman Michael Y; Koumenis Costas; Spiegel Sarah; Chen Ching-Shih; Graf Martin; Curiel David T; Fisher Paul B; Grant Steven; Dent Paul
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells.
Molecular pharmacology 2008;73(4):1168-84.
2008: Stoff-Khalili Mariam A; Rivera Angel A; Nedeljkovic-Kurepa Ana; DeBenedetti Arrigo; Li Xiao-Lin; Odaka Yoshinobu; Podduturi Jagat; Sibley Don A; Siegal Gene P; Stoff Alexander; Young Scott; Zhu Zheng B; Curiel David T; Mathis J Michael
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control.
Breast cancer research and treatment 2008;108(1):43-55.
2008: Yacoub Adly; Gupta Pankaj; Park Margaret A; Rhamani Mohammed; Hamed Hossein; Hanna David; Zhang Guo; Sarkar Devanand; Lebedeva Irina V; Emdad Luni; Koumenis Costas; Curiel David T; Grant Steven; Fisher Paul B; Dent Paul
Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling.
Molecular cancer therapeutics 2008;7(2):314-29.
2008: Yacoub Adly; Park Margaret A; Gupta Pankaj; Rahmani Mohammed; Zhang Guo; Hamed Hossein; Hanna David; Sarkar Devanand; Lebedeva Irina V; Emdad Luni; Sauane Moira; Vozhilla Nicollaq; Spiegel Sarah; Koumenis Costas; Graf Martin; Curiel David T; Grant Steven; Fisher Paul B; Dent Paul
Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.
Molecular cancer therapeutics 2008;7(2):297-313.
2008: Saini Vaibhav; Martyshkin Dmitri V; Mirov Sergei B; Perez Alex; Perkins Guy; Ellisman Mark H; Towner Victoria D; Wu Hongju; Pereboeva Larisa; Borovjagin Anton; Curiel David T; Everts Maaike
An adenoviral platform for selective self-assembly and targeted delivery of nanoparticles.
Small (Weinheim an der Bergstrasse, Germany) 2008;4(2):262-9.
2008: Uchino J; Takayama K; Harada A; Sone T; Harada T; Curiel D T; Kuroki M; Nakanishi Y
Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan.
Cancer gene therapy 2008;15(2):94-100.
2008: Huang D; Pereboev A V; Korokhov N; He R; Larocque L; Gravel C; Jaentschke B; Tocchi M; Casley W L; Lemieux M; Curiel D T; Chen W; Li X
Significant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells.
Gene therapy 2008;15(4):298-308.
2008: Sarkar Devanand; Dent Paul; Curiel David T; Fisher Paul B
Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: not insurmountable therapeutic problems.
Cancer biology & therapy 2008;7(1):109-12.
2008: Brumlik Michael J; Daniel Benjamin J; Waehler Reinhard; Curiel David T; Giles Francis J; Curiel Tyler J
Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy.
Expert opinion on drug delivery 2008;5(1):87-103.
2008: Numnum T Michael; Makhija Sharmila; Lu Baogen; Wang Minghui; Rivera Angel; Stoff-Khalili Mariam; Alvarez Ronald D; Zhu Zeng Bian; Curiel David T
Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines.
Gynecologic oncology 2008;108(1):34-41.
2008: Schierer Stephan; Hesse Andrea; Müller Ina; Kämpgen Eckhart; Curiel David T; Schuler Gerold; Steinkasserer Alexander; Nettelbeck Dirk M
Modulation of viability and maturation of human monocyte-derived dendritic cells by oncolytic adenoviruses.
International journal of cancer. Journal international du cancer 2008;122(1):219-29.
2008: Palomba Stefano; Curiel David T; Kakar Sham S; Kotsuji Fumikazu
Welcome to journal of ovarian research.
Journal of ovarian research 2008;1(1):1.
2008: Matthews Qiana L; Yang PingAr; Wu Qi; Belousova Natalya; Rivera Angel A; Stoff-Khalili Mariam A; Waehler Reinhard; Hsu Hui-Chen; Li Zan; Li Jing; Mountz John D; Wu Hongju; Curiel David T
Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach.
Virology journal 2008;5():98.
2008: Wu Hongju; Curiel David T
Fiber-modified adenoviruses for targeted gene therapy.
Methods in molecular biology (Clifton, N.J.) 2008;434():113-32.
2008: Haviv Yosef S; Curiel David T
Gene therapy for renal cancer.
Contributions to nephrology 2008;159():135-50.
2007: Mitchell Clint; Park Maragret A; Zhang Guo; Yacoub Adly; Curiel David T; Fisher Paul B; Roberts John D; Grant Steven; Dent Paul
Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.
Molecular cancer therapeutics 2007;6(12 Pt 1):3101-12.
2007: Emdad Luni; Lebedeva Irina V; Su Zao-Zhong; Sarkar Devanand; Dent Paul; Curiel David T; Fisher Paul B
Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells.
Molecular cancer therapeutics 2007;6(11):2985-94.
2007: Zhu Zeng B; Mathis J Michael; Makhija Sharmila K; Lu Baogen; Wang Minghui; Ji Shaonin; Rivera Angel A; Rosenthal Eben L; Siegal Gene P; Curiel David T
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck.
International journal of oncology 2007;31(5):1213-22.
2007: Fisher Paul B; Sarkar Devanand; Lebedeva Irina V; Emdad Luni; Gupta Pankaj; Sauane Moira; Su Zao-zhong; Grant Steven; Dent Paul; Curiel David T; Senzer Neil; Nemunaitis John
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.
Toxicology and applied pharmacology 2007;224(3):300-7.
2007: Stoff-Khalili Mariam A; Rivera Angel A; Mathis J Michael; Banerjee N Sanjib; Moon Amanda S; Hess A; Rocconi Rodney P; Numnum T Michael; Everts M; Chow Louise T; Douglas Joanne T; Siegal Gene P; Zhu Zeng B; Bender Hans Georg; Dall Peter; Stoff Alexander; Pereboeva Larissa; Curiel David T
Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma.
Breast cancer research and treatment 2007;105(2):157-67.
2007: Ulasov Ilya V; Rivera Angel A; Han Yu; Curiel David T; Zhu Zeng B; Lesniak Maciej S
Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells.
Journal of neurosurgery 2007;107(3):617-27.
2007: Mitchell Clint; Kabolizadeh Peyman; Ryan John; Roberts John D; Yacoub Adly; Curiel David T; Fisher Paul B; Hagan Michael P; Farrell Nicholas P; Grant Steven; Dent Paul
Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Molecular pharmacology 2007;72(3):704-14.
2007: Waehler Reinhard; Russell Stephen J; Curiel David T
Engineering targeted viral vectors for gene therapy.
Nature reviews. Genetics 2007;8(8):573-87.
2007: Ulasov Ilya V; Zhu Zeng B; Tyler Matthew A; Han Yu; Rivera Angel A; Khramtsov Andrey; Curiel David T; Lesniak Maciej S
Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma.
Human gene therapy 2007;18(7):589-602.
2007: Van Houdt Winan J; Wu Hongju; Glasgow Joel N; Lamfers Martine L; Dirven Clemens M; Gillespie G Yancey; Curiel David T; Haviv Yosef S
Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models.
Neuro-oncology 2007;9(3):280-90.
2007: Sarkar Devanand; Lebedeva Irina V; Su Zao-zhong; Park Eun-Sook; Chatman Lejuan; Vozhilla Nicollaq; Dent Paul; Curiel David T; Fisher Paul B
Eradication of therapy-resistant human prostate tumors using a cancer terminator virus.
Cancer research 2007;67(11):5434-42.
2007: Li Hua-Jung; Everts Maaike; Pereboeva Larisa; Komarova Svetlana; Idan Anat; Curiel David T; Herschman Harvey R
Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter.
Cancer research 2007;67(11):5354-61.
2007: Sarkar Devanand; Lebedeva Irina V; Gupta Pankaj; Emdad Luni; Sauane Moira; Dent Paul; Curiel David T; Fisher Paul B
Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?
Expert opinion on biological therapy 2007;7(5):577-86.
2007: Tsuruta Yuko; Pereboeva Larisa; Glasgow Joel N; Rein Daniel T; Kawakami Yosuke; Alvarez Ronald D; Rocconi Rodney P; Siegal Gene P; Dent Paul; Fisher Paul B; Curiel David T
A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(9):2777-83.
2007: Reynolds Ann M; Xia Wei; Holmes Mark D; Hodge Sandra J; Danilov Sergei; Curiel David T; Morrell Nicholas W; Reynolds Paul N
Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1182-92.
2007: Stoff Alexander; Rivera Angel A; Mathis J Michael; Moore Steven T; Banerjee N S; Everts Maaike; Espinosa-de-los-Monteros Antonio; Novak Zdenek; Vasconez Luis O; Broker Thomas R; Richter Dirk F; Feldman Dale; Siegal Gene P; Stoff-Khalili Mariam A; Curiel David T
Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds.
Journal of molecular medicine (Berlin, Germany) 2007;85(5):481-96.
2007: Page John G; Tian Baohong; Schweikart Karen; Tomaszewski Joseph; Harris Ray; Broadt Trevor; Polley-Nelson Judith; Noker Patricia E; Wang Minghui; Makhija Sharmila; Aurigemma Rose; Curiel David T; Alvarez Ronald D
Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer.
American journal of obstetrics and gynecology 2007;196(4):389.e1-9; discussion 389.e9-10.
2007: Pereboeva L; Komarova S; Roth J; Ponnazhagan S; Curiel D T
Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus.
Gene therapy 2007;14(8):627-37.
2007: Lam J T; Hemminki A; Kanerva A; Lee K B; Blackwell J L; Desmond R; Siegal G P; Curiel D T
A three-dimensional assay for measurement of viral-induced oncolysis.
Cancer gene therapy 2007;14(4):421-30.
2007: Perreau Matthieu; Mennechet Franck; Serratrice Nicolas; Glasgow Joel N; Curiel David T; Wodrich Harald; Kremer Eric J
Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy.
Journal of virology 2007;81(7):3272-84.
2007: Witlox M A; Lamfers M L; Wuisman P I J M; Curiel D T; Siegal G P
Evolving gene therapy approaches for osteosarcoma using viral vectors: review.
Bone 2007;40(4):797-812.
2007: Rocconi Rodney P; Zhu Zeng B; Stoff-Khalili Mariam; Rivera Angel A; Lu Baogen; Wang Minghui; Alvarez Ronald D; Curiel David T; Makhija Sharmila K
Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd).
Gynecologic oncology 2007;105(1):113-21.
2007: Valerie Kristoffer; Yacoub Adly; Hagan Michael P; Curiel David T; Fisher Paul B; Grant Steven; Dent Paul
Radiation-induced cell signaling: inside-out and outside-in.
Molecular cancer therapeutics 2007;6(3):789-801.
2007: Ugai Hideyo; Borovjagin Anton V; Le Long P; Wang Minghui; Curiel David T
Thermostability/infectivity defect caused by deletion of the core protein V gene in human adenovirus type 5 is rescued by thermo-selectable mutations in the core protein X precursor.
Journal of molecular biology 2007;366(4):1142-60.
2007: Tang Y; Han T; Everts M; Zhu Z B; Gillespie G Y; Curiel D T; Wu H
Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model.
Gene therapy 2007;14(6):523-32.
2007: Lebedeva Irina V; Washington Ilyas; Sarkar Devanand; Clark Jennifer A; Fine Robert L; Dent Paul; Curiel David T; Turro Nicholas J; Fisher Paul B
Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3484-9.
2007: Yoshio-Hoshino Naoko; Adachi Yasuo; Aoki Chieko; Pereboev Alexander; Curiel David T; Nishimoto Norihiro
Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor.
Cancer research 2007;67(3):871-5.
2007: Stoff-Khalili Mariam A; Rivera Angel A; Stoff Alexander; Michael Mathis J; Rocconi Rodney P; Matthews Qiana L; Numnum Michael T; Herrmann Isabell; Dall Peter; Eckhoff Devin E; Douglas Joanne T; Siegal Gene P; Zhu Zeng B; Curiel David T
Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer.
International journal of cancer. Journal international du cancer 2007;120(4):935-41.
2007: Zhu Zeng B; Rivera Angel A; Makhija Sharmila K; Lu Baogen; Wang Minghui; Izumi Miiru; Cerfolio Robert J; Stoff-Khalili Mariam A; Zhou Fen; Takayama Koichi; Siegal Gene P; Curiel David T
Targeting lung cancer using an infectivity enhanced CXCR4-CRAd.
Lung cancer (Amsterdam, Netherlands) 2007;55(2):145-56.
2007: Preuss Meredith A; Curiel David T
Gene therapy: science fiction or reality?
Southern medical journal 2007;100(1):101-4.
2007: Matthews Qiana L; Curiel David T
Gene therapy: human germline genetic modifications--assessing the scientific, socioethical, and religious issues.
Southern medical journal 2007;100(1):98-100.
2007: Yacoub Adly; Hawkins William; Hanna David; Young Hong; Park Margaret A; Grant Mark; Roberts John D; Curiel David T; Fisher Paul B; Valerie Kristoffer; Grant Steven; Hagan Michael P; Dent Paul
Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment.
Molecular pharmacology 2007;71(1):259-75.
2007: Takayama K; Reynolds P N; Adachi Y; Kaliberova L; Uchino J; Nakanishi Y; Curiel D T
Vascular endothelial growth factor promoter-based conditionally replicative adenoviruses for pan-carcinoma application.
Cancer gene therapy 2007;14(1):105-16.
2006: Smith Bruce F; Curiel David T; Ternovoi Vladimir V; Borovjagin Anton V; Baker Henry J; Cox Nancy; Siegal Gene P
Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs.
Cancer biotherapy & radiopharmaceuticals 2006;21(6):601-6.
2006: Short Joshua J; Vasu Chenthamarakshan; Holterman Mark J; Curiel David T; Pereboev Alexander
Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors.
Virus research 2006;122(1-2):144-53.
2006: Rocconi Rodney P; Numnum Michael T; Zhu Zeng B; Lu Baogen; Wang Minghui; Rivera Angel A; Stoff-Khalili Mariam; Alvarez Ronald D; Curiel David T; Makhija Sharmila
Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy.
Gynecologic oncology 2006;103(3):985-9.
2006: Zhu Zeng Bian; Chen Yabing; Makhija Sharmila K; Lu Baogen; Wang Minghui; Rivera Angel A; Yamamoto Masato; Wang Shuyi; Siegal Gene P; Curiel David T; McDonald Jay M
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.
International journal of oncology 2006;29(5):1319-29.
2006: Abid Md Ruhul; Shih Shu-Ching; Otu Hasan H; Spokes Katherine C; Okada Yoshiaki; Curiel David T; Minami Takashi; Aird William C
A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression.
The Journal of biological chemistry 2006;281(46):35544-53.
2006: Belousova Natalya; Harris Raymond; Zinn Kurt; Rhodes-Selser Mary Ann; Kotov Alexander; Kotova Olga; Wang Minghui; Aurigemma Rosemarie; Zhu Zeng B; Curiel David T; Alvarez Ronald D
Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette.
Molecular pharmacology 2006;70(5):1488-93.
2006: Hedley Susan J; Chen Jian; Mountz John D; Li Jing; Curiel David T; Korokhov Nikolay; Kovesdi Imre
Targeted and shielded adenovectors for cancer therapy.
Cancer immunology, immunotherapy : CII 2006;55(11):1412-9.
2006: Matthews Qiana L; Sibley Don A; Wu Hongju; Li Jing; Stoff-Khalili Mariam A; Waehler Reinhard; Mathis J Michael; Curiel David T
Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion.
Molecular imaging : official journal of the Society for Molecular Imaging 2006;5(4):510-9.
2006: Hakkarainen Tanja; Hemminki Akseli; Curiel David T; Wahlfors Jarmo
A conditionally replicative adenovirus that codes for a TK-GFP fusion protein (Ad5Delta24TK-GFP) for evaluation of the potency of oncolytic virotherapy combined with molecular chemotherapy.
International journal of molecular medicine 2006;18(4):751-9.
2006: Yacoub Adly; Gilfor Donna; Hawkins William; Park Margaret A; Hanna David; Hagan Michael P; Curiel David T; Fisher Paul B; Grant Steven; Dent Paul
MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo.
Cancer biology & therapy 2006;5(10):1332-9.
2006: Zhu Zeng B; Makhija Sharmila K; Lu Baogen; Wang Minghui; Wang Shuyi; Takayama Koichi; Siegal Gene P; Reynolds Paul N; Curiel David T
Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(7):701-11.
2006: Stoff Alexander; Rivera Angel A; Banerjee N S; Mathis J Michael; Espinosa-de-los-Monteros Antonio; Le Long P; De la Torre Jorge I; Vasconez Luis O; Broker Thomas R; Richter Dirk F; Stoff-Khalili Mariam A; Curiel David T
Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(5):608-17.
2006: Tyler Matthew A; Ulasov Ilya V; Borovjagin Anton; Sonabend Adam M; Khramtsov Andrey; Han Yu; Dent Paul; Fisher Paul B; Curiel David T; Lesniak Maciej S
Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus.
Molecular cancer therapeutics 2006;5(9):2408-16.
2006: Adachi Yasuo; Aoki Chieko; Yoshio-Hoshino Naoko; Takayama Koichi; Curiel David T; Nishimoto Norihiro
Interleukin-6 induces both cell growth and VEGF production in malignant mesotheliomas.
International journal of cancer. Journal international du cancer 2006;119(6):1303-11.
2006: Gupta Pankaj; Su Zao-zhong; Lebedeva Irina V; Sarkar Devanand; Sauane Moira; Emdad Luni; Bachelor Michael A; Grant Steven; Curiel David T; Dent Paul; Fisher Paul B
mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine.
Pharmacology & therapeutics 2006;111(3):596-628.
2006: Glasgow J N; Everts M; Curiel D T
Transductional targeting of adenovirus vectors for gene therapy.
Cancer gene therapy 2006;13(9):830-44.
2006: Ternovoi Vladimir V; Curiel David T; Smith Bruce F; Siegal Gene P
Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.
Laboratory investigation; a journal of technical methods and pathology 2006;86(8):748-66.
2006: Le Long P; Le Helen N; Nelson Amy R; Matthews David A; Yamamoto Masato; Curiel David T
Core labeling of adenovirus with EGFP.
Virology 2006;351(2):291-302.
2006: Emdad Luni; Sarkar Devanand; Lebedeva Irina V; Su Zao-Zhong; Gupta Pankaj; Mahasreshti Parameshwar J; Dent Paul; Curiel David T; Fisher Paul B
Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.
Journal of cellular physiology 2006;208(2):298-306.
2006: Bauerschmitz Gerd J; Guse Kilian; Kanerva Anna; Menzel Artur; Herrmann Isabell; Desmond Renee A; Yamamoto Masato; Nettelbeck Dirk M; Hakkarainen Tanja; Dall Peter; Curiel David T; Hemminki Akseli
Triple-targeted oncolytic adenoviruses featuring the cox2 promoter, E1A transcomplementation, and serotype chimerism for enhanced selectivity for ovarian cancer cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(2):164-74.
2006: Breidenbach Martina; Rein Daniel T; Schöndorf Thomas; Khan Kiran N; Herrmann Isabell; Schmidt Torsten; Reynolds Paul N; Vlodavsky Israel; Haviv Yosef S; Curiel David T
A new targeting approach for breast cancer gene therapy using the heparanase promoter.
Cancer letters 2006;240(1):114-22.
2006: Stoff-Khalili M A; Dall P; Curiel D T
Gene therapy for carcinoma of the breast.
Cancer gene therapy 2006;13(7):633-47.
2006: Chen Jian; Hsu Hui-Chen; Zajac Allan J; Wu Qi; Yang Pingar; Xu Xin; McPherson Sylvia A; Li Jun; Curiel David T; Mountz John D
In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin.
Human gene therapy 2006;17(6):669-82.
2006: Nakayama Masaharu; Both Gerald W; Banizs Boglarka; Tsuruta Yuko; Yamamoto Seiji; Kawakami Yosuke; Douglas Joanne T; Tani Kenzaburo; Curiel David T; Glasgow Joel N
An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice.
Virology 2006;350(1):103-15.
2006: Stoff-Khalili M A; Rivera A A; Le L P; Stoff A; Everts M; Contreras J L; Chen D; Teng L; Rots M G; Haisma H J; Rocconi R P; Bauerschmitz G J; Rein D T; Yamamoto M; Siegal G P; Dall P; Michael Mathis J; Curiel D T
Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents.
Cancer gene therapy 2006;13(6):606-18.
2006: Kangasniemi Lotta; Kiviluoto Tuula; Kanerva Anna; Raki Mari; Ranki Tuuli; Sarkioja Merja; Wu Hongju; Marini Frank; Höckerstedt Krister; Isoniemi Helena; Alfthan Henrik; Stenman Ulf-Håkan; Curiel David T; Hemminki Akseli
Infectivity-enhanced adenoviruses deliver efficacy in clinical samples and orthotopic models of disseminated gastric cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(10):3137-44.
2006: Mathis J Michael; Stewart Phoebe L; Zhu Zheng B; Curiel David T
Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(9):2651-6.
2006: Van Houdt Winan J; Haviv Yosef S; Lu Baogen; Wang Minghui; Rivera Angel A; Ulasov Ilya V; Lamfers Martine L M; Rein Daniel; Lesniak Maciej S; Siegal Gene P; Dirven Clemens M F; Curiel David T; Zhu Zeng B
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
Journal of neurosurgery 2006;104(4):583-92.
2006: Everts Maaike; Saini Vaibhav; Leddon Jennifer L; Kok Robbert J; Stoff-Khalili Mariam; Preuss Meredith A; Millican C Leigh; Perkins Guy; Brown Joshua M; Bagaria Hitesh; Nikles David E; Johnson Duane T; Zharov Vladimir P; Curiel David T
Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy.
Nano letters 2006;6(4):587-91.
2006: Komarova Svetlana; Kawakami Yosuke; Stoff-Khalili Mariam A; Curiel David T; Pereboeva Larisa
Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses.
Molecular cancer therapeutics 2006;5(3):755-66.
2006: Noureddini Sam C; Krendelshchikov Alexander; Simonenko Vera; Hedley Susan J; Douglas Joanne T; Curiel David T; Korokhov Nikolay
Generation and selection of targeted adenoviruses embodying optimized vector properties.
Virus research 2006;116(1-2):185-95.
2006: Le L P; Rivera A A; Glasgow J N; Ternovoi V V; Wu H; Wang M; Smith B F; Siegal G P; Curiel D T
Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells.
Gene therapy 2006;13(5):389-99.
2006: Mahasreshti Parameshwar J; Kataram Manjula; Wu Hongju; Yalavarthy Laxmi Priya; Carey Delicia; Fisher Paul B; Chada Sunil; Alvarez Ronald D; Haisma Hidde J; Dent Paul; Curiel David T
Ovarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy.
Gynecologic oncology 2006;100(3):521-32.
2006: Rein Daniel T; Breidenbach M; Curiel David T
Current developments in adenovirus-based cancer gene therapy.
Future oncology (London, England) 2006;2(1):137-43.
2006: Curiel David T; Zhu Zeng B
Combining chemotherapy with virotherapy: a novel treatment strategy for malignant pleural mesothelioma.
Cancer biology & therapy 2006;5(2):236-7.
2006: Le Long P; Le Helen N; Dmitriev Igor P; Davydova Julia G; Gavrikova Tatyana; Yamamoto Seiji; Curiel David T; Yamamoto Masato
Dynamic monitoring of oncolytic adenovirus in vivo by genetic capsid labeling.
Journal of the National Cancer Institute 2006;98(3):203-14.
2006: Yamamoto M; Nishimoto N; Davydova J; Kishimoto T; Curiel D T
Suppressor of cytokine signaling-1 expression by infectivity-enhanced adenoviral vector inhibits IL-6-dependent proliferation of multiple myeloma cells.
Cancer gene therapy 2006;13(2):194-202.
2006: Gomez-Manzano Candelaria; Alonso Marta M; Yung W K Alfred; McCormick Frank; Curiel David T; Lang Frederick F; Jiang Hong; Bekele B Nebiyou; Zhou Xian; Alemany Ramon; Fueyo Juan
Delta-24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):556-62.
2006: Lee Choon-Taek; Lee Yoon-Jin; Kwon Sung-Youn; Lee Jaeho; Kim Kwang Il; Park Kyung-Ho; Kang Joo Hyun; Yoo Chul-Gyu; Kim Young Whan; Han Sung Koo; Chung June-Key; Shim Young-Soo; Curiel David T; Carbone David P
In vivo imaging of adenovirus transduction and enhanced therapeutic efficacy of combination therapy with conditionally replicating adenovirus and adenovirus-p27.
Cancer research 2006;66(1):372-7.
2006: Hedley S J; Auf der Maur A; Hohn S; Escher D; Barberis A; Glasgow J N; Douglas J T; Korokhov N; Curiel D T
An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery.
Gene therapy 2006;13(1):88-94.
2005: Zharov Vladimir P; Kim Jin-Woo; Curiel David T; Everts Maaike
Self-assembling nanoclusters in living systems: application for integrated photothermal nanodiagnostics and nanotherapy.
Nanomedicine : nanotechnology, biology, and medicine 2005;1(4):326-45.
2005: Rocconi Rodney P; Numnum T Michael; Stoff-Khalili Mariam; Makhija Sharmila; Alvarez Ronald D; Curiel David T
Targeted gene therapy for ovarian cancer.
Current gene therapy 2005;5(6):643-53.
2005: Le Long P; Li Jing; Ternovoi Vladimir V; Siegal Gene P; Curiel David T
Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein.
The Journal of general virology 2005;86(Pt 12):3201-8.
2005: Izumi Miiru; Kawakami Yosuke; Glasgow Joel N; Belousova Natalya; Everts Maaike; Kim-Park SangAe; Yamamoto Seiji; Wang Minghui; Le Long P; Reynolds Paul N; Curiel David T
In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model.
The journal of gene medicine 2005;7(12):1517-25.
2005: Stoff-Khalili M A; Rivera A A; Glasgow J N; Le L P; Stoff A; Everts M; Tsuruta Y; Kawakami Y; Bauerschmitz G J; Mathis J M; Pereboeva L; Seigal G P; Dall P; Curiel D T
A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy.
Gene therapy 2005;12(23):1696-706.
2005: Passineau Michael J; Siegal Gene P; Everts Maaike; Pereboev Alexander; Jhala Darshana; Wang Minghui; Zhu Zeng B; Park Sangae Kim; Curiel David T; Nelson Gina M
The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma.
Leukemia & lymphoma 2005;46(11):1627-1638.
2005: Mathis J Michael; Stoff-Khalili Mariam A; Curiel David T
Oncolytic adenoviruses - selective retargeting to tumor cells.
Oncogene 2005;24(52):7775-91.
2005: Stoff-Khalili Mariam A; Stoff Alexander; Rivera Angel A; Mathis J Michael; Everts Maaike; Wang Minghui; Kawakami Yosuke; Waehler Reinhard; Mathews Quiana L; Yamamoto Masato; Rocconi Rodney P; Siegal Gene P; Richter Dirk F; Dall Peter; Zhu Zeng B; Curiel David T
Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.
Cancer biology & therapy 2005;4(11):1203-10.
2005: Noureddini Sam C; Curiel David T
Genetic targeting strategies for adenovirus.
Molecular pharmaceutics 2005;2(5):341-7.
2005: Tsuruta Yuko; Pereboeva Larisa; Glasgow Joel N; Luongo Cindy L; Komarova Svetlana; Kawakami Yosuke; Curiel David T
Reovirus sigma1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway.
Biochemical and biophysical research communications 2005;335(1):205-14.
2005: Uchino Junji; Takayama Koichi; Harada Akiko; Kawakami Yosuke; Inoue Hiroyuki; Curiel David T; Nakanishi Yoichi
Infectivity enhanced, hTERT promoter-based conditionally replicative adenoviruses are useful for SCLC treatment.
Cancer gene therapy 2005;12(9):737-48.
2005: Yamamoto Masato; Curiel David T
Cancer gene therapy.
Technology in cancer research & treatment 2005;4(4):315-30.
2005: Li Jing; Le Long; Sibley Don A; Mathis J Michael; Curiel David T
Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion.
Virology 2005;338(2):247-58.
2005: Zhu Zeng B; Makhija Sharmila K; Lu Baogen; Wang Minghui; Rivera Angel A; Kim-Park Sangae; Ulasov Ilya V; Zhou Fen; Alvarez Ronald D; Siegal Gene P; Curiel David T
Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo.
International journal of oncology 2005;27(1):237-46.
2005: Dent Paul; Yacoub Adly; Grant Steven; Curiel David T; Fisher Paul B
MDA-7/IL-24 regulates proliferation, invasion and tumor cell radiosensitivity: a new cancer therapy?
Journal of cellular biochemistry 2005;95(4):712-9.
2005: Chen J; Zajac A J; McPherson S A; Hsu H-C; Yang P; Wu Q; Xu X; Wang X; Fujihashi K; Curiel D T; Mountz J D
Primary adenovirus-specific cytotoxic T lymphocyte response occurs after viral clearance and liver enzyme elevation.
Gene therapy 2005;12(13):1079-88.
2005: Everts M; Kim-Park S-A; Preuss M A; Passineau M J; Glasgow J N; Pereboev A V; Mahasreshti P J; Grizzle W E; Reynolds P N; Curiel D T
Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors.
Gene therapy 2005;12(13):1042-8.
2005: Hosokawa Mami; Kadota Ritsuko; Shichijo Shigeki; Itoh Kyogo; Dmitriev Igor; Krasnykh Victor; Curiel David T; Takue Yoichi; Wakasugi Hiro; Takashima Shigemitsu; Heike Yuji
Cell cycle arrest and apoptosis induced by SART-1 gene transduction.
Anticancer research 2005;25(3B):1983-90.
2005: Korokhov Nikolay; Noureddini Sam C; Curiel David T; Santegoets Saskia J A M; Scheper Rik J; de Gruijl Tanja D
A single-component CD40-targeted adenovirus vector displays highly efficient transduction and activation of dendritic cells in a human skin substrate system.
Molecular pharmaceutics 2005;2(3):218-23.
2005: Tekant Yaman; Davydova Julia; Ramirez Pedro J; Curiel David T; Vickers Selwyn M; Yamamoto Masato
Oncolytic adenoviral therapy in gallbladder carcinoma.
Surgery 2005;137(5):527-35.
2005: Borovjagin Anton V; Krendelchtchikov Alexandre; Ramesh Nagarajan; Yu De-Chao; Douglas Joanne T; Curiel David T
Complex mosaicism is a novel approach to infectivity enhancement of adenovirus type 5-based vectors.
Cancer gene therapy 2005;12(5):475-86.
2005: Engesaeter Birgit Ø; Bonsted Anette; Berg Kristian; Høgset Anders; Engebråten Olav; Fodstad Øystein; Curiel David T; Maelandsmo Gunhild M
PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles.
Cancer gene therapy 2005;12(5):439-48.
2005: Korokhov Nikolay; de Gruijl Tanja D; Aldrich Wayne A; Triozzi Pierre L; Banerjee Papia T; Gillies Stephen D; Curiel Tyler J; Douglas Joanne T; Scheper Rik J; Curiel David T
High efficiency transduction of dendritic cells by adenoviral vectors targeted to DC-SIGN.
Cancer biology & therapy 2005;4(3):289-94.
2005: Wu Hongju; Han Tie; Belousova Natalya; Krasnykh Victor; Kashentseva Elena; Dmitriev Igor; Kataram Manjula; Mahasreshti Parameshwar J; Curiel David T
Identification of sites in adenovirus hexon for foreign peptide incorporation.
Journal of virology 2005;79(6):3382-90.
2005: Rein Daniel T; Breidenbach Martina; Kirby Tyler O; Han Tie; Siegal Gene P; Bauerschmitz Gerd J; Wang Minghui; Nettelbeck Dirk M; Tsuruta Yuko; Yamamoto Masato; Dall Peter; Hemminki Akseli; Curiel David T
A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(3):1327-35.
2005: Lu B; Makhija S K; Nettelbeck D M; Rivera A A; Wang M; Komarova S; Zhou F; Yamamoto M; Haisma H J; Alvarez R D; Curiel D T; Zhu Z B
Evaluation of tumor-specific promoter activities in melanoma.
Gene therapy 2005;12(4):330-8.
2005: Wang Minghui; Hemminki Akseli; Siegal Gene P; Barnes Mack N; Dmitriev Igor; Krasnykh Victor; Liu Bin; Curiel David T; Alvarez Ronald D
Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.
Gynecologic oncology 2005;96(2):341-8.
2005: Volk Andrea L; Rivera Angel A; Page Grier P; Salazar-Gonzalez Jesus F; Nettelbeck Dirk M; Matthews Qiana L; Curiel David T
Employment of microarray analysis to characterize biologic differences associated with tropism-modified adenoviral vectors: utilization of non-native cellular entry pathways.
Cancer gene therapy 2005;12(2):162-74.
2005: Ono Hidetaka A; Davydova Julia G; Adachi Yasuo; Takayama Koichi; Barker Shannon D; Reynolds Paul N; Krasnykh Victor N; Kunisaki Chikara; Shimada Hiroshi; Curiel David T; Yamamoto Masato
Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer.
Journal of gastroenterology 2005;40(1):31-42.
2005: Ternovoi Vladimir V; Le Long P; Belousova Natalya; Smith Bruce F; Siegal Gene P; Curiel David T
Productive replication of human adenovirus type 5 in canine cells.
Journal of virology 2005;79(2):1308-11.
2005: Breidenbach M; Rein D T; Everts M; Glasgow J N; Wang M; Passineau M J; Alvarez R D; Korokhov N; Curiel D T
Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy.
Gene therapy 2005;12(2):187-93.
2005: Kanerva A; Zinn K R; Peng K-W; Ranki T; Kangasniemi L; Chaudhuri T R; Desmond R A; Wang M; Takayama K; Hakkarainen T; Alfthan H; Stenman U-H; Curiel D T; Hemminki A
Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus.
Gene therapy 2005;12(1):87-94.
2005: Mahendra Gandham; Kumar Sanjay; Isayeva Tatyana; Mahasreshti Parameshwar J; Curiel David T; Stockardt Cecil R; Grizzle William E; Alapati Vidya; Singh Raj; Siegal Gene P; Meleth Sreelatha; Ponnazhagan Selvarangan
Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor.
Cancer gene therapy 2005;12(1):26-34.
2005: Stoff-Khalili Mariam A; Stoff Alexander; Rivera Angel A; Banerjee Nilam S; Everts Maaike; Young Scott; Siegal Gene P; Richter Dirk F; Wang Minghui; Dall Peter; Mathis J Michael; Zhu Zeng B; Curiel David T
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system.
Breast cancer research : BCR 2005;7(6):R1141-52.
2005: Balyasnikova Irina V; Metzger Roman; Visintine David J; Dimasius Vidas; Sun Zhu-Li; Berestetskaya Yuliya V; McDonald Timothy D; Curiel David T; Minshall Richard D; Danilov Sergei M
Selective rat lung endothelial targeting with a new set of monoclonal antibodies to angiotensin I-converting enzyme.
Pulmonary pharmacology & therapeutics 2005;18(4):251-67.
2005: Grill Jacques; Lamfers Martine L M; van Beusechem Victor W; van der Valk Paul; Huisman Anne; Sminia Peter; Alemany Ramon; Curiel David T; Vandertop W Peter; Gerritsen Winald R; Dirven Clemens M F
Oncolytic virotherapy of meningiomas in vitro with replication-competent adenovirus.
Neurosurgery 2005;56(1):146-53; discussion 153-4.
2004: Stoff-Khalili M A; Dall P; Curiel D T
From gene therapy to virotherapy for ovarian cancer.
Minerva ginecologica 2004;56(6):503-14.
2004: Kirby Tyler O; Rivera Angel; Rein Daniel; Wang Minghui; Ulasov Ilya; Breidenbach Martina; Kataram Manjula; Contreras Juan L; Krumdieck Carlos; Yamamoto Masato; Rots Marianne G; Haisma Hidde J; Alvarez Ronald D; Mahasreshti Parameshwar J; Curiel David T
A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8697-703.
2004: Rivera A A; Davydova J; Schierer S; Wang M; Krasnykh V; Yamamoto M; Curiel D T; Nettelbeck D M
Combining high selectivity of replication with fiber chimerism for effective adenoviral oncolysis of CAR-negative melanoma cells.
Gene therapy 2004;11(23):1694-702.
2004: Lam John T; Kanerva Anna; Bauerschmitz Gerd J; Takayama Koichi; Suzuki Kaori; Yamamoto Masato; Bhoola Snehal M; Liu Bin; Wang Minghui; Barnes Mack N; Alvarez Ronald D; Siegal Gene P; Curiel David T; Hemminki Akseli
Inter-patient variation in efficacy of five oncolytic adenovirus candidates for ovarian cancer therapy.
The journal of gene medicine 2004;6(12):1333-42.
2004: Liang Qianwa; Yamamoto Masato; Curiel David T; Herschman Harvey R
Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(6):395-404.
2004: Liang Qianwa; Dmitriev Igor; Kashentseva Elena; Curiel David T; Herschman Harvey R
Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(6):385-94.
2004: Rein Daniel T; Breidenbach Martina; Nettelbeck Dirk M; Kawakami Yosuke; Siegal Gene P; Huh Warner K; Wang Minghui; Hemminki Akseli; Bauerschmitz Gerd J; Yamamoto Masato; Adachi Yasuo; Takayama Koichi; Dall Peter; Curiel David T
Evaluation of tissue-specific promoters in carcinomas of the cervix uteri.
The journal of gene medicine 2004;6(11):1281-9.
2004: Everts Maaike; Curiel David T
Transductional targeting of adenoviral cancer gene therapy.
Current gene therapy 2004;4(3):337-46.
2004: Lee Choon-Taek; Park Kyung-Ho; Yanagisawa Kiyoshi; Adachi Yasushi; Ohm Joyce E; Nadaf Sorena; Dikov Mikhail M; Curiel David T; Carbone David P
Combination therapy with conditionally replicating adenovirus and replication defective adenovirus.
Cancer research 2004;64(18):6660-5.
2004: Contreras Juan L; Xie Dong; Mays Jimmy; Smyth Cheryl A; Eckstein Christopher; Rahemtulla Firoz G; Young Carlton J; Anthony Thompson J; Bilbao Guadalupe; Curiel David T; Eckhoff Devin E
A novel approach to xenotransplantation combining surface engineering and genetic modification of isolated adult porcine islets.
Surgery 2004;136(3):537-47.
2004: Pereboeva Larisa; Komarova Svetlana; Mahasreshti Parameshwar J; Curiel David T
Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors.
Virus research 2004;105(1):35-46.
2004: Rein Daniel T; Breidenbach Martina; Wu Hongju; Han Tie; Haviv Yosef S; Wang Minghui; Kirby Tyler O; Kawakami Yosuke; Dall Peter; Alvarez Ronald D; Curiel David T
Gene transfer to cervical cancer with fiber-modified adenoviruses.
International journal of cancer. Journal international du cancer 2004;111(5):698-704.
2004: Leath Charles A; Kataram Manjula; Bhagavatula Pradeep; Gopalkrishnan Rahul V; Dent Paul; Fisher Paul B; Pereboev Alexander; Carey Delicia; Lebedeva Irina V; Haisma Hidde J; Alvarez Ronald D; Curiel David T; Mahasreshti Parameshwar J
Infectivity enhanced adenoviral-mediated mda-7/IL-24 gene therapy for ovarian carcinoma.
Gynecologic oncology 2004;94(2):352-62.
2004: Bauerschmitz Gerd J; Kanerva Anna; Wang Minghui; Herrmann Isabell; Shaw Denise R; Strong Theresa V; Desmond Renee; Rein Daniel T; Dall Peter; Curiel David T; Hemminki Akseli
Evaluation of a selectively oncolytic adenovirus for local and systemic treatment of cervical cancer.
International journal of cancer. Journal international du cancer 2004;111(2):303-9.
2004: Yacoub Adly; Mitchell Clint; Hong Young; Gopalkrishnan Rahul V; Su Zhao-Zhong; Gupta Pankaj; Sauane Moria; Lebedeva Irina V; Curiel David T; Mahasreshti Parameshwar J; Rosenfeld Myrna R; Broaddus William C; James C David; Grant Steven; Fisher Paul B; Dent Paul
MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
Cancer biology & therapy 2004;3(8):739-51.
2004: Ferrer Miriam; de Winter Johan P; Mastenbroek D C Jeroen; Curiel David T; Gerritsen Winald R; Giaccone Giuseppe; Kruyt Frank A E
Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA.
Cancer gene therapy 2004;11(8):539-46.
2004: Zhu Zeng B; Makhija Sharmila K; Lu Baogen; Wang Minghui; Rivera Angel A; Preuss Meredith; Zhou Fen; Siegal Gene P; Alvarez Ronald D; Curiel David T
Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.
Virology 2004;325(1):116-28.
2004: Haviv Yosef S; van Houdt Winan J; Lu Baogen; Curiel David T; Zhu Zeng B
Transcriptional targeting in renal cancer cell lines via the human CXCR4 promoter.
Molecular cancer therapeutics 2004;3(6):687-91.
2004: Glasgow Joel N; Kremer Eric J; Hemminki Akseli; Siegal Gene P; Douglas Joanne T; Curiel David T
An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism.
Virology 2004;324(1):103-16.
2004: Breidenbach Martina; Rein Daniel T; Wang Minghui; Nettelbeck Dirk M; Hemminki Akseli; Ulasov Ilya; Rivera Angel R; Everts Maaike; Alvarez Ronald D; Douglas Joanne T; Curiel David T
Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy.
Human gene therapy 2004;15(5):509-18.
2004: Preuss Meredith A; Lam John T; Wang Minghui; Leath Charles A; Kataram Manjula; Mahasreshti Parameshwar J; Alvarez Ronald D; Curiel David T
Transcriptional blocks limit adenoviral replication in primary ovarian tumor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3189-94.
2004: Pereboev Alexander V; Nagle Jill M; Shakhmatov Mikhail A; Triozzi Pierre L; Matthews Qiana L; Kawakami Yosuke; Curiel David T; Blackwell Jerry L
Enhanced gene transfer to mouse dendritic cells using adenoviral vectors coated with a novel adapter molecule.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(5):712-20.
2004: Short Joshua J; Pereboev Alexander V; Kawakami Yosuke; Vasu Chenthamarakshan; Holterman Mark J; Curiel David T
Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors.
Virology 2004;322(2):349-59.
2004: Wu H; Han T; Lam J T; Leath C A; Dmitriev I; Kashentseva E; Barnes M N; Alvarez R D; Curiel D T
Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy.
Gene therapy 2004;11(10):874-8.
2004: Le Long P; Everts Maaike; Dmitriev Igor P; Davydova Julia G; Yamamoto Masato; Curiel David T
Fluorescently labeled adenovirus with pIX-EGFP for vector detection.
Molecular imaging : official journal of the Society for Molecular Imaging 2004;3(2):105-16.
2004: Banerjee N Sanjib; Rivera Angel A; Wang Minghui; Chow Louise T; Broker Thomas R; Curiel David T; Nettelbeck Dirk M
Analyses of melanoma-targeted oncolytic adenoviruses with tyrosinase enhancer/promoter-driven E1A, E4, or both in submerged cells and organotypic cultures.
Molecular cancer therapeutics 2004;3(4):437-49.
2004: Zhu Z B; Makhija S K; Lu B; Wang M; Kaliberova L; Liu B; Rivera A A; Nettelbeck D M; Mahasreshti P J; Leath C A; Yamamoto M; Alvarez R D; Curiel D T
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Gene therapy 2004;11(7):645-8.
2004: Zhu Zeng B; Makhija Sharmila K; Lu Baogen; Wang Minghui; Kaliberova Lioudmila; Liu Bin; Rivera Angel A; Nettelbeck Dirk M; Mahasreshti Parameshwar J; Leath Charles A; Barker Shannon; Yamaoto Masato; Li Fengzhi; Alvarez Ronald D; Curiel David T
Transcriptional targeting of tumors with a novel tumor-specific survivin promoter.
Cancer gene therapy 2004;11(4):256-62.
2004: Leath Charles A; Douglas Joanne T; Curiel David T; Alvarez Ronald D
Single-chain antibodies: A therapeutic modality for cancer gene therapy (review).
International journal of oncology 2004;24(4):765-71.
2004: Glasgow J N; Bauerschmitz G J; Curiel D T; Hemminki A
Transductional and transcriptional targeting of adenovirus for clinical applications.
Current gene therapy 2004;4(1):1-14.
2004: Grandi Paola; Wang Samuel; Schuback Deborah; Krasnykh Victor; Spear Matthew; Curiel David T; Manservigi Roberto; Breakefield Xandra O
HSV-1 virions engineered for specific binding to cell surface receptors.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(3):419-27.
2004: Rivera Angel A; Wang Minghui; Suzuki Kaori; Uil Taco G; Krasnykh Victor; Curiel David T; Nettelbeck Dirk M
Mode of transgene expression after fusion to early or late viral genes of a conditionally replicating adenovirus via an optimized internal ribosome entry site in vitro and in vivo.
Virology 2004;320(1):121-34.
2004: Kanerva A; Bauerschmitz G J; Yamamoto M; Lam J T; Alvarez R D; Siegal G P; Curiel D T; Hemminki A
A cyclooxygenase-2 promoter-based conditionally replicating adenovirus with enhanced infectivity for treatment of ovarian adenocarcinoma.
Gene therapy 2004;11(6):552-9.
2004: Bonner James A; Buchsbaum Donald J; Rogers Buck E; Grizzle William E; Trummell Hoa Q; Curiel David T; Fiveash John B; Ove Roger; Raisch Kevin P
Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells.
International journal of radiation oncology, biology, physics 2004;58(3):950-8.
2004: Verwijnen Suzanne M; Sillevis Smith Peter A E; Hoeben Rob C; Rabelink Martin J W E; Wiebe Leonard; Curiel David T; Hemminki Akseli; Krenning Eric P; de Jong Marion
Molecular imaging and treatment of malignant gliomas following adenoviral transfer of the herpes simplex virus-thymidine kinase gene and the somatostatin receptor subtype 2 gene.
Cancer biotherapy & radiopharmaceuticals 2004;19(1):111-20.
2004: Witlox Adhiambo M; Van Beusechem Victor W; Molenaar Bonnie; Bras Hans; Schaap Gerard R; Alemany Ramon; Curiel David T; Pinedo Herbert M; Wuisman Paul I J M; Gerritsen Winald R
Conditionally replicative adenovirus with tropism expanded towards integrins inhibits osteosarcoma tumor growth in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):61-7.
2004: Nettelbeck Dirk M; Rivera Angel A; Kupsch Jörg; Dieckmann Detlef; Douglas Joanne T; Kontermann Roland E; Alemany Ramon; Curiel David T
Retargeting of adenoviral infection to melanoma: combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA.
International journal of cancer. Journal international du cancer 2004;108(1):136-45.
2004: Pereboeva Larisa; Curiel David T
Cellular vehicles for cancer gene therapy: current status and future potential.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2004;18(6):361-85.
2004: Contreras Juan L; Smyth Cheryl A; Curiel David T; Eckhoff Devin E
Nonhuman primate models in type 1 diabetes research.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2004;45(3):334-42.
2004: Bonner James A; Buchsbaum Donald J; Russo Suzanne M; Fiveash John B; Trummell Hoa Q; Curiel David T; Raisch Kevin P
Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression.
International journal of radiation oncology, biology, physics 2004;59(2 Suppl):2-10.
2004: Timares Laura; Douglas Joanne T; Tillman Bryan W; Krasnykh Victor; Curiel David T
Adenovirus-mediated gene delivery to dendritic cells.
Methods in molecular biology (Clifton, N.J.) 2004;246():139-54.
2004: Yamamoto Masato; Curiel David T
Nonreplicating DNA viral vectors for suicide gene therapy: the adenoviral vectors.
Methods in molecular medicine 2004;90():61-70.
2003: Korokhov Nikolay; Mikheeva Galina; Krendelshchikov Alexander; Belousova Natalya; Simonenko Vera; Krendelshchikova Valentina; Pereboev Alexander; Kotov Alexander; Kotova Olga; Triozzi Pierre L; Aldrich Wayne A; Douglas Joanne T; Lo Kin-Ming; Banerjee Papia T; Gillies Stephen D; Curiel David T; Krasnykh Victor
Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge.
Journal of virology 2003;77(24):12931-40.
2003: Buskens Christianne J; Marsman Willem A; Wesseling John G; Offerhaus G Johan A; Yamamoto Masato; Curiel David T; Bosma Piter J; van Lanschot J Jan B
A genetically retargeted adenoviral vector enhances viral transduction in esophageal carcinoma cell lines and primary cultured esophageal resection specimens.
Annals of surgery 2003;238(6):815-24; discussion 825-6.
2003: Belousova Natalya; Korokhov Nikolay; Krendelshchikova Valentina; Simonenko Vera; Mikheeva Galina; Triozzi Pierre L; Aldrich Wayne A; Banerjee Papia T; Gillies Stephen D; Curiel David T; Krasnykh Victor
Genetically targeted adenovirus vector directed to CD40-expressing cells.
Journal of virology 2003;77(21):11367-77.
2003: Haviv Yosef S; Takayama Koichi; Nagi Peter A; Tousson Albert; Cook William; Wang Minghui; Lam John T; Naito Seiji; Lei Xiaosheng; Carey Delicia E; Curiel David T
Modulation of renal glomerular disease using remote delivery of adenoviral-encoded solubletype II TGF-beta receptor fusion molecule.
The journal of gene medicine 2003;5(10):839-51.
2003: Stam A G M; Santegoets S J A M; Westers T M; Sombroek C C; Janssen J J W M; Tillman B W; van de Loosdrecht A A; Pinedo H M; Curiel D T; Ossenkoppele G J; Scheper R J; de Gruijl T D
CD40-targeted adenoviral GM-CSF gene transfer enhances and prolongs the maturation of human CML-derived dendritic cells upon cytokine deprivation.
British journal of cancer 2003;89(7):1162-5.
2003: Yamamoto Masato; Davydova Julia; Wang Minghui; Siegal Gene P; Krasnykh Victor; Vickers Selwyn M; Curiel David T
Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer.
Gastroenterology 2003;125(4):1203-18.
2003: Nettelbeck Dirk M; Curiel David T
Tumor-busting viruses.
Scientific American 2003;289(4):68-75.
2003: Volk Andrea L; Rivera Angel A; Kanerva Anna; Bauerschmitz Gerd; Dmitriev Igor; Nettelbeck Dirk M; Curiel David T
Enhanced adenovirus infection of melanoma cells by fiber-modification: incorporation of RGD peptide or Ad5/3 chimerism.
Cancer biology & therapy 2003;2(5):511-5.
2003: Kanerva Anna; Zinn Kurt R; Chaudhuri Tandra R; Lam John T; Suzuki Kaori; Uil Taco G; Hakkarainen Tanja; Bauerschmitz Gerd J; Wang Minghui; Liu Bin; Cao Zhihong; Alvarez Ronald D; Curiel David T; Hemminki Akseli
Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):449-58.
2003: Kirby Tyler O; Curiel David T; Alvarez Ronald D
Gene therapy for ovarian cancer: progress and potential.
Hematology/oncology clinics of North America 2003;17(4):1021-50.
2003: Hemminki Akseli; Wang Minghui; Hakkarainen Tanja; Desmond Renee A; Wahlfors Jarmo; Curiel David T
Production of an EGFR targeting molecule from a conditionally replicating adenovirus impairs its oncolytic potential.
Cancer gene therapy 2003;10(8):583-8.
2003: Haviv Yosef S; Curiel David T
Engineering regulatory elements for conditionally-replicative adeno-viruses.
Current gene therapy 2003;3(4):357-85.
2003: Fisher Paul B; Gopalkrishnan Rahul V; Chada Sunil; Ramesh Rajagopal; Grimm Elizabeth A; Rosenfeld Myrna R; Curiel David T; Dent Paul
mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.
Cancer biology & therapy 2003;2(4 Suppl 1):S23-37.
2003: Contreras Juan L; Wu Hongju; Smyth Cheryl A; Eckstein Christopher P; Young Carlton J; Seki Toshiro; Bilbao Guadalupe; Curiel David T; Eckhoff Devin E
Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets.
Transplantation 2003;76(1):252-61.
2003: Mahasreshti Parameshwar J; Kataram Manjula; Wang Ming H; Stockard Cecil R; Grizzle William E; Carey Delicia; Siegal Gene P; Haisma Hidde J; Alvarez Ronald D; Curiel David T
Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2701-10.
2003: Barker S D; Dmitriev I P; Nettelbeck D M; Liu B; Rivera A A; Alvarez R D; Curiel D T; Hemminki A
Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma.
Gene therapy 2003;10(14):1198-204.
2003: Contreras Juan L; Smyth Cheryl A; Bilbao Guadalupe; Eckstein Christopher; Young Carlton J; Thompson J Anthony; Curiel David T; Eckhoff Devin E
Coupling endoplasmic reticulum stress to cell death program in isolated human pancreatic islets: effects of gene transfer of Bcl-2.
Transplant international : official journal of the European Society for Organ Transplantation 2003;16(7):537-42.
2003: Nettelbeck D M; Rivera A A; Davydova J; Dieckmann D; Yamamoto M; Curiel D T
Cyclooxygenase-2 promoter for tumour-specific targeting of adenoviral vectors to melanoma.
Melanoma research 2003;13(3):287-92.
2003: Brandão Joana G; Scheper Rik J; Lougheed Sinéad M; Curiel David T; Tillman Bryan W; Gerritsen Winald R; van den Eertwegh Alfons J M; Pinedo Herbert M; Haisma Hidde J; de Gruijl Tanja D
CD40-targeted adenoviral gene transfer to dendritic cells through the use of a novel bispecific single-chain Fv antibody enhances cytotoxic T cell activation.
Vaccine 2003;21(19-20):2268-72.
2003: Noya Francisco; Balagué Cristina; Banerjee N Sanjib; Curiel David T; Broker Thomas R; Chow Louise T
Activation of adenovirus early promoters and lytic phase in differentiated strata of organotypic cultures of human keratinocytes.
Journal of virology 2003;77(11):6533-40.
2003: Takayama Koichi; Reynolds Paul N; Short Joshua J; Kawakami Yosuke; Adachi Yasuo; Glasgow Joel N; Rots Marianne G; Krasnykh Victor; Douglas Joanne T; Curiel David T
A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism.
Virology 2003;309(2):282-93.
2003: Fueyo Juan; Alemany Ramon; Gomez-Manzano Candelaria; Fuller Gregory N; Khan Asadullah; Conrad Charles A; Liu Ta-Jen; Jiang Hong; Lemoine Michael G; Suzuki Kaori; Sawaya Raymond; Curiel David T; Yung W K Alfred; Lang Frederick F
Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway.
Journal of the National Cancer Institute 2003;95(9):652-60.
2003: Lam John T; Bauerschmitz Gerd J; Kanerva Anna; Barker Shannon D; Straughn J Michael; Wang Minghui; Barnes Mack N; Blackwell Jerry L; Siegal Gene P; Alvarez Ronald D; Curiel David T; Hemminki Akseli
Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids.
Cancer gene therapy 2003;10(5):377-87.
2003: Curiel Tyler J; Wei Shuang; Dong Haidong; Alvarez Xavier; Cheng Pui; Mottram Peter; Krzysiek Roman; Knutson Keith L; Daniel Ben; Zimmermann Maria Carla; David Odile; Burow Matthew; Gordon Alan; Dhurandhar Nina; Myers Leann; Berggren Ruth; Hemminki Akseli; Alvarez Ronald D; Emilie Dominique; Curiel David T; Chen Lieping; Zou Weiping
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.
Nature medicine 2003;9(5):562-7.
2003: Barker Shannon D; Coolidge Candace J; Kanerva Anna; Hakkarainen Tanja; Yamamoto Masato; Liu Bin; Rivera Angel A; Bhoola Snehal M; Barnes Mack N; Alvarez Ronald D; Curiel David T; Hemminki Akseli
The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy.
The journal of gene medicine 2003;5(4):300-10.
2003: Nagi Peter; Vickers Selwyn M; Davydova Julia; Adachi Yasuo; Takayama Koichi; Barker Shannon; Krasnykh Victor; Curiel David T; Yamamoto Masato
Development of a therapeutic adenoviral vector for cholangiocarcinoma combining tumor-restricted gene expression and infectivity enhancement.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(3):364-71.
2003: Kawakami Yosuke; Li Hui; Lam John T; Krasnykh Victor; Curiel David T; Blackwell Jerry L
Substitution of the adenovirus serotype 5 knob with a serotype 3 knob enhances multiple steps in virus replication.
Cancer research 2003;63(6):1262-9.
2003: Arafat Waleed O; Buchsbaum Donald J; Gómez-Navarro Jesús; Tawil Sarah A; Olsen Christine; Xiang Jialing; El-Akad Hazem; Salama Anwar M; Badib Ahmed O; Stackhouse Murray A; Curiel David T
An adenovirus encoding proapoptotic Bax synergistically radiosensitizes malignant glioma.
International journal of radiation oncology, biology, physics 2003;55(4):1037-50.
2003: Hemminki Akseli; Kanerva Anna; Kremer Eric J; Bauerschmitz Gerd J; Smith Bruce F; Liu Bin; Wang Minghui; Desmond Renee A; Keriel Anne; Barnett Brian; Baker Henry J; Siegal Gene P; Curiel David T
A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(2):163-73.
2003: Hemminki Akseli; Kanerva Anna; Liu Bin; Wang Minghui; Alvarez Ronald D; Siegal Gene P; Curiel David T
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research 2003;63(4):847-53.
2003: Hakkarainen Tanja; Hemminki Akseli; Pereboev Alexander V; Barker Shannon D; Asiedu Clement K; Strong Theresa V; Kanerva Anna; Wahlfors Jarmo; Curiel David T
CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):619-24.
2003: Uil Taco G; Seki Toshiro; Dmitriev Igor; Kashentseva Elena; Douglas Joanne T; Rots Marianne G; Middeldorp Jaap M; Curiel David T
Generation of an adenoviral vector containing an addition of a heterologous ligand to the serotype 3 fiber knob.
Cancer gene therapy 2003;10(2):121-4.
2003: Yamamoto Masato; Davydova Julia; Takayama Koichi; Alemany Ramon; Curiel David T
Transcription initiation activity of adenovirus left-end sequence in adenovirus vectors with e1 deleted.
Journal of virology 2003;77(2):1633-7.
2003: Kawakami Yosuke; Curiel Tyler J; Curiel David T
Cancer gene therapy and immunotherapy.
Cancer chemotherapy and biological response modifiers 2003;21():327-37.
2003: Pereboeva L; Komarova S; Mikheeva G; Krasnykh V; Curiel D T
Approaches to utilize mesenchymal progenitor cells as cellular vehicles.
Stem cells (Dayton, Ohio) 2003;21(4):389-404.
2002: Wu Hongju; Dmitriev Igor; Kashentseva Elena; Seki Toshiro; Wang Minghui; Curiel David T
Construction and characterization of adenovirus serotype 5 packaged by serotype 3 hexon.
Journal of virology 2002;76(24):12775-82.
2002: Zhang Huang-Ge; Xie Jinfu; Dmitriev Igor; Kashentseva Elena; Curiel David T; Hsu Hui-Chen; Mountz John D
Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or production.
Journal of virology 2002;76(23):12023-31.
2002: Suzuki Kaori; Alemany Ramón; Yamamoto Masato; Curiel David T
The presence of the adenovirus E3 region improves the oncolytic potency of conditionally replicative adenoviruses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3348-59.
2002: Grill Jacques; Lamfers Martine L M; van Beusechem Victor W; Dirven Clemens M; Pherai D Shareen; Kater Mathijs; Van der Valk Paul; Vogels Ronald; Vandertop W Peter; Pinedo Herbert M; Curiel David T; Gerritsen Winald R
The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(5):609-14.
2002: Sullivan Deborah E; Mondelli Mario U; Curiel David T; Krasnykh Viktor; Mikheeva Gallina; Gaglio Paul; Morris Cindy B; Dash Srikanta; Gerber Michael A
Construction and characterization of an intracellular single-chain human antibody to hepatitis C virus non-structural 3 protein.
Journal of hepatology 2002;37(5):660-8.
2002: de Gruijl Tanja D; Luykx-de Bakker Sylvia A; Tillman Bryan W; van den Eertwegh Alfons J M; Buter Jan; Lougheed Sinéad M; van der Bij Gerben J; Safer A Mahmoud; Haisma Hidde J; Curiel David T; Scheper Rik J; Pinedo Herbert M; Gerritsen Winald R
Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5322-31.
2002: Bilbao Guadalupe; Contreras Juan Luis; Curiel David T
Genetically engineered intracellular single-chain antibodies in gene therapy.
Molecular biotechnology 2002;22(2):191-211.
2002: Lamfers Martine L M; Grill Jacques; Dirven Clemens M F; Van Beusechem Victor W; Geoerger Birgit; Van Den Berg Jaap; Alemany Ramon; Fueyo Juan; Curiel David T; Vassal Gilles; Pinedo Herbert M; Vandertop W Peter; Gerritsen Winald R
Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.
Cancer research 2002;62(20):5736-42.
2002: Asiedu Clement; Dong Sai S; Pereboev Alexander; Wang Weila; Navarro Jesus; Curiel David T; Thomas Judith M
Rhesus monocyte-derived dendritic cells modified to over-express TGF-beta1 exhibit potent veto activity.
Transplantation 2002;74(5):629-37.
2002: Conry Robert M; Curiel David T; Strong Theresa V; Moore Susan E; Allen Karen O; Barlow Daunte L; Shaw Denise R; LoBuglio Albert F
Safety and immunogenicity of a DNA vaccine encoding carcinoembryonic antigen and hepatitis B surface antigen in colorectal carcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2782-7.
2002: Barnett Brian G; Tillman Bryan W; Curiel David T; Douglas Joanne T
Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(3):377-85.
2002: Wu Hongju; Seki Toshiro; Dmitriev Igor; Uil Taco; Kashentseva Elena; Han Tie; Curiel David T
Double modification of adenovirus fiber with RGD and polylysine motifs improves coxsackievirus-adenovirus receptor-independent gene transfer efficiency.
Human gene therapy 2002;13(13):1647-53.
2002: Witlox M A; Van Beusechem V W; Grill J; Haisma H J; Schaap G; Bras J; Van Diest P; De Gast A; Curiel D T; Pinedo H M; Gerritsen W R; Wuisman P I J M
Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma.
The journal of gene medicine 2002;4(5):510-6.
2002: Kim M; Zinn K R; Barnett B G; Sumerel L A; Krasnykh V; Curiel D T; Douglas J T
The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells.
European journal of cancer (Oxford, England : 1990) 2002;38(14):1917-26.
2002: Pereboev A V; Asiedu C K; Kawakami Y; Dong S S; Blackwell J L; Kashentseva E A; Triozzi P L; Aldrich W A; Curiel D T; Thomas J M; Dmitriev I P
Coxsackievirus-adenovirus receptor genetically fused to anti-human CD40 scFv enhances adenoviral transduction of dendritic cells.
Gene therapy 2002;9(17):1189-93.
2002: Belousova Natalya; Krendelchtchikova Valentina; Curiel David T; Krasnykh Victor
Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.
Journal of virology 2002;76(17):8621-31.
2002: Hemminki Akseli; Wang Minghui; Desmond Renee A; Strong Theresa V; Alvarez Ronald D; Curiel David T
Serum and ascites neutralizing antibodies in ovarian cancer patients treated with intraperitoneal adenoviral gene therapy.
Human gene therapy 2002;13(12):1505-14.
2002: Dirven Clemens M F; Grill Jacques; Lamfers Martine L M; Van der Valk Paul; Leonhart Angelique M; Van Beusechem Victor W; Haisma Hidde J; Pinedo Herbert M; Curiel David T; Vandertop W Peter; Gerritsen Winald R
Gene therapy for meningioma: improved gene delivery with targeted adenoviruses.
Journal of neurosurgery 2002;97(2):441-9.
2002: Nettelbeck Dirk M; Rivera Angel A; Balagué Cristina; Alemany Ramon; Curiel David T
Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter.
Cancer research 2002;62(16):4663-70.
2002: Kaliberov Sergey A; Buchsbaum Donald J; Gillespie G Yancey; Curiel David T; Arafat Waleed O; Carpenter Mark; Stackhouse Murray A
Adenovirus-mediated transfer of BAX driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):190-8.
2002: Haviv Yosef S; Blackwell Jerry L; Kanerva Anna; Nagi Peter; Krasnykh Victor; Dmitriev Igor; Wang Minghui; Naito Seiji; Lei Xiaosheng; Hemminki Akseli; Carey Delicia; Curiel David T
Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors.
Cancer research 2002;62(15):4273-81.
2002: Seki T; Dmitriev I; Suzuki K; Kashentseva E; Takayama K; Rots M; Uil T; Wu H; Wang M; Curiel D T
Fiber shaft extension in combination with HI loop ligands augments infectivity for CAR-negative tumor targets but does not enhance hepatotropism in vivo.
Gene therapy 2002;9(16):1101-8.
2002: Dmitriev Igor P; Kashentseva Elena A; Curiel David T
Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX.
Journal of virology 2002;76(14):6893-9.
2002: van der Poel H G; Molenaar B; van Beusechem V W; Haisma H J; Rodriguez R; Curiel D T; Gerritsen W R
Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer.
The Journal of urology 2002;168(1):266-72.
2002: Kanerva Anna; Wang Minghui; Bauerschmitz Gerd J; Lam John T; Desmond Renee A; Bhoola Snehal M; Barnes Mack N; Alvarez Ronald D; Siegal Gene P; Curiel David T; Hemminki Akseli
Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):695-704.
2002: Zhang Huang-Ge; Xie Jinfu; Xu Liang; Yang Pingar; Xu Xin; Sun Sheher; Wang Yongming; Curiel David T; Hsu Hui-Chen; Mountz John D
Hepatic DR5 induces apoptosis and limits adenovirus gene therapy product expression in the liver.
Journal of virology 2002;76(11):5692-700.
2002: Hemminki Akseli; Zinn Kurt R; Liu Bin; Chaudhuri Tandra R; Desmond Renee A; Rogers Buck E; Barnes Mack N; Alvarez Ronald D; Curiel David T
In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus.
Journal of the National Cancer Institute 2002;94(10):741-9.
2002: Zinn Kurt R; Chaudhuri Tandra R; Krasnykh Victor N; Buchsbaum Donald J; Belousova Natalya; Grizzle William E; Curiel David T; Rogers Buck E
Gamma camera dual imaging with a somatostatin receptor and thymidine kinase after gene transfer with a bicistronic adenovirus in mice.
Radiology 2002;223(2):417-25.
2002: Barnes Mack N; Coolidge Candace J; Hemminki Akseli; Alvarez Ronald D; Curiel David T
Conditionally replicative adenoviruses for ovarian cancer therapy.
Molecular cancer therapeutics 2002;1(6):435-9.
2002: Adachi Yasuo; Matsubara Shyuichiro; Muramatsu Takashi; Curiel David T; Reynolds Paul N
Midkine promoter-based adenoviral suicide gene therapy to midkine-positive pediatric tumor.
Journal of pediatric surgery 2002;37(4):588-92.
2002: Haviv Yosef S; Takayama Koichi; Glasgow Joel N; Blackwell Jerry L; Wang Minghui; Lei Xiaosheng; Curiel David T
A model system for the design of armed replicating adenoviruses using p53 as a candidate transgene.
Molecular cancer therapeutics 2002;1(5):321-8.
2002: Bilbao Guadalupe; Contreras Juan L; Dmitriev Igor; Smyth Cheryl A; Jenkins Stacie; Eckhoff Devin; Thomas Francis; Thomas Judith; Curiel David T
Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(3):237-43.
2002: Bauerschmitz Gerd J; Nettelbeck Dirk M; Kanerva Anna; Baker Andrew H; Hemminki Akseli; Reynolds Paul N; Curiel David T
The flt-1 promoter for transcriptional targeting of teratocarcinoma.
Cancer research 2002;62(5):1271-4.
2002: Bauerschmitz Gerd J; Lam John T; Kanerva Anna; Suzuki Kaori; Nettelbeck Dirk M; Dmitriev Igor; Krasnykh Victor; Mikheeva Galina V; Barnes Mack N; Alvarez Ronald D; Dall Peter; Alemany Ramon; Curiel David T; Hemminki Akseli
Treatment of ovarian cancer with a tropism modified oncolytic adenovirus.
Cancer research 2002;62(5):1266-70.
2002: Kruyt Frank A E; Curiel David T
Toward a new generation of conditionally replicating adenoviruses: pairing tumor selectivity with maximal oncolysis.
Human gene therapy 2002;13(4):485-95.
2002: Holm Per S; Bergmann Stephan; Jurchott Karsten; Lage Hermann; Brand Karsten; Ladhoff Axel; Mantwill Klaus; Curiel David T; Dobbelstein Matthias; Dietel Manfred; Gansbacher Bernd; Royer Hans-Dieter
YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter.
The Journal of biological chemistry 2002;277(12):10427-34.
2002: Arafat W O; Gómez-Navarro J; Buchsbaum D J; Xiang J; Wang M; Casado E; Barker S D; Mahasreshti P J; Haisma H J; Barnes M N; Siegal G P; Alvarez R D; Hemminki A; Nettelbeck D M; Curiel D T
Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv.
Gene therapy 2002;9(4):256-62.
2002: Curiel Tyler J; Curiel David T
Tumor immunotherapy: inching toward the finish line.
The Journal of clinical investigation 2002;109(3):311-2.
2002: Seki Toshiro; Dmitriev Igor; Kashentseva Elena; Takayama Koichi; Rots Marianne; Suzuki Kaori; Curiel David T
Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines.
Journal of virology 2002;76(3):1100-8.
2002: Contreras Juan L; Bilbao Guadalupe; Smyth Cheryl A; Eckhoff Devin E; Jiang Xiao L; Jenkins Stacie; Thomas Francis T; Curiel David T; Thomas Judith M
Cytoprotection of pancreatic islets before and early after transplantation using gene therapy.
Kidney international 2002;61(1 Suppl):S79-84.
2002: Reynolds Paul N; Curiel David T
New generation adenoviral vectors improve gene transfer by coxsackie and adenoviral receptor-independent cell entry.
Kidney international 2002;61(1 Suppl):S24-31.
2002: Kashentseva Elena A; Seki Toshiro; Curiel David T; Dmitriev Igor P
Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain.
Cancer research 2002;62(2):609-16.
2002: Kanerva Anna; Mikheeva Galina V; Krasnykh Victor; Coolidge Candace J; Lam John T; Mahasreshti Parameshwar J; Barker Shannon D; Straughn Michael; Barnes Mack N; Alvarez Ronald D; Hemminki Akseli; Curiel David T
Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):275-80.
2002: Clement Asiedu; Pereboev Alexander; Curiel David T; Dong Sai Sai; Hutchings Anne; Thomas Judith M
Converting nonhuman primate dendritic cells into potent antigen-specific cellular immunosuppressants by genetic modification.
Immunologic research 2002;26(1-3):297-302.
2001: Wesseling J G; Yamamoto M; Adachi Y; Bosma P J; van Wijland M; Blackwell J L; Li H; Reynolds P N; Dmitriev I; Vickers S M; Huibregtse K; Curiel D T
Midkine and cyclooxygenase-2 promoters are promising for adenoviral vector gene delivery of pancreatic carcinoma.
Cancer gene therapy 2001;8(12):990-6.
2001: Li H; Haviv Y S; Derdeyn C A; Lam J; Coolidge C; Hunter E; Curiel D T; Blackwell J L
Human immunodeficiency virus type 1-mediated syncytium formation is compatible with adenovirus replication and facilitates efficient dispersion of viral gene products and de novo-synthesized virus particles.
Human gene therapy 2001;12(18):2155-65.
2001: Haviv Y S; Blackwell J L; Li H; Wang M; Lei X; Curiel D T
Heat shock and heat shock protein 70i enhance the oncolytic effect of replicative adenovirus.
Cancer research 2001;61(23):8361-5.
2001: Adachi Y; Reynolds P N; Yamamoto M; Wang M; Takayama K; Matsubara S; Muramatsu T; Curiel D T
A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging.
Cancer research 2001;61(21):7882-8.
2001: Huh W K; Gomez-Navarro J; Arafat W O; Xiang J; Mahasreshti P J; Alvarez R D; Barnes M N; Curiel D T
Bax-induced apoptosis as a novel gene therapy approach for carcinoma of the cervix.
Gynecologic oncology 2001;83(2):370-7.
2001: Ponnazhagan S; Mahendra G; Curiel D T; Shaw D R
Adeno-associated virus type 2-mediated transduction of human monocyte-derived dendritic cells: implications for ex vivo immunotherapy.
Journal of virology 2001;75(19):9493-501.
2001: Alemany R; Curiel D T
CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors.
Gene therapy 2001;8(17):1347-53.
2001: Hemminki A; Belousova N; Zinn K R; Liu B; Wang M; Chaudhuri T R; Rogers B E; Buchsbaum D J; Siegal G P; Barnes M N; Gomez-Navarro J; Curiel D T; Alvarez R D
An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(3):223-31.
2001: Reynolds P N; Nicklin S A; Kaliberova L; Boatman B G; Grizzle W E; Balyasnikova I V; Baker A H; Danilov S M; Curiel D T
Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo.
Nature biotechnology 2001;19(9):838-42.
2001: Hemminki A; Dmitriev I; Liu B; Desmond R A; Alemany R; Curiel D T
Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule.
Cancer research 2001;61(17):6377-81.
2001: Ponnazhagan S; Curiel D T; Shaw D R; Alvarez R D; Siegal G P
Adeno-associated virus for cancer gene therapy.
Cancer research 2001;61(17):6313-21.
2001: Buchsbaum D J; Curiel D T
Gene therapy for the treatment of cancer.
Cancer biotherapy & radiopharmaceuticals 2001;16(4):275-88.
2001: Casado E; Nettelbeck D M; Gomez-Navarro J; Hemminki A; Gonzalez Baron M; Siegal G P; Barnes M N; Alvarez R D; Curiel D T
Transcriptional targeting for ovarian cancer gene therapy.
Gynecologic oncology 2001;82(2):229-37.
2001: Reynolds P N; Holmes M D; Adachi Y; Kaliberova L; Curiel D T
A novel system for mitigation of ectopic transgene expression induced by adenoviral vectors.
Gene therapy 2001;8(16):1271-5.
2001: Contreras J L; Bilbao G; Smyth C; Eckhoff D E; Xiang X L; Jenkins S; Cartner S; Curiel D T; Thomas F T; Thomas J M
Gene transfer of the Bcl-2 gene confers cytoprotection to isolated adult porcine pancreatic islets exposed to xenoreactive antibodies and complement.
Surgery 2001;130(2):166-74.
2001: Casado E; Gomez-Navarro J; Yamamoto M; Adachi Y; Coolidge C J; Arafat W O; Barker S D; Wang M H; Mahasreshti P J; Hemminki A; Gonzalez-Baron M; Barnes M N; Pustilnik T B; Siegal G P; Alvarez R D; Curiel D T
Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2496-504.
2001: Balagué C; Noya F; Alemany R; Chow L T; Curiel D T
Human papillomavirus E6E7-mediated adenovirus cell killing: selectivity of mutant adenovirus replication in organotypic cultures of human keratinocytes.
Journal of virology 2001;75(16):7602-11.
2001: Pereboev A; Pereboeva L; Curiel D T
Phage display of adenovirus type 5 fiber knob as a tool for specific ligand selection and validation.
Journal of virology 2001;75(15):7107-13.
2001: Suzuki K; Curiel D T
[Viral therapy of cancer]
Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición 2001;53(4):346-56.
2001: Mahasreshti P J; Navarro J G; Kataram M; Wang M H; Carey D; Siegal G P; Barnes M N; Nettelbeck D M; Alvarez R D; Hemminki A; Curiel D T
Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):2057-66.
2001: Wesseling J G; Bosma P J; Krasnykh V; Kashentseva E A; Blackwell J L; Reynolds P N; Li H; Parameshwar M; Vickers S M; Jaffee E M; Huibregtse K; Curiel D T; Dmitriev I
Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors.
Gene therapy 2001;8(13):969-76.
2001: Barker S D; Casado E; Gomez-Navarro J; Xiang J; Arafat W; Mahasreshti P; Pustilnik T B; Hemminki A; Siegal G P; Alvarez R D; Curiel D T
An immunomagnetic-based method for the purification of ovarian cancer cells from patient-derived ascites.
Gynecologic oncology 2001;82(1):57-63.
2001: Zhang H G; Wang Y M; Xie J F; Liang X; Hsu H C; Zhang X; Douglas J; Curiel D T; Mountz J D
Recombinant adenovirus expressing adeno-associated virus cap and rep proteins supports production of high-titer recombinant adeno-associated virus.
Gene therapy 2001;8(9):704-12.
2001: Krasnykh V; Belousova N; Korokhov N; Mikheeva G; Curiel D T
Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin.
Journal of virology 2001;75(9):4176-83.
2001: Contreras J L; Bilbao G; Smyth C A; Jiang X L; Eckhoff D E; Jenkins S M; Thomas F T; Curiel D T; Thomas J M
Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene.
Transplantation 2001;71(8):1015-23.
2001: Heike Y; Kasono K; Kunisaki C; Hama S; Saijo N; Tsuruo T; Kuntz D A; Rose D R; Curiel D T
Overcoming multi-drug resistance using an intracellular anti-MDR1 sFv.
International journal of cancer. Journal international du cancer 2001;92(1):115-22.
2001: Grill J; Van Beusechem V W; Van Der Valk P; Dirven C M; Leonhart A; Pherai D S; Haisma H J; Pinedo H M; Curiel D T; Gerritsen W R
Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):641-50.
2001: Yamamoto M; Alemany R; Adachi Y; Grizzle W E; Curiel D T
Characterization of the cyclooxygenase-2 promoter in an adenoviral vector and its application for the mitigation of toxicity in suicide gene therapy of gastrointestinal cancers.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(3):385-94.
2001: Douglas J T; Kim M; Sumerel L A; Carey D E; Curiel D T
Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary ad receptors.
Cancer research 2001;61(3):813-7.
2001: Suzuki K; Fueyo J; Krasnykh V; Reynolds P N; Curiel D T; Alemany R
A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(1):120-6.
2000: Rots M G; Curiel D T
Towards the optimal vector for prostate cancer gene therapy; a caPCURE meeting report.
Cancer gene therapy 2000;7(12):1507-10.
2000: Krasnykh V; Dmitriev I; Navarro J G; Belousova N; Kashentseva E; Xiang J; Douglas J T; Curiel D T
Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity.
Cancer research 2000;60(24):6784-7.
2000: Reynolds P N; Zinn K R; Gavrilyuk V D; Balyasnikova I V; Rogers B E; Buchsbaum D J; Wang M H; Miletich D J; Grizzle W E; Douglas J T; Danilov S M; Curiel D T
A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(6):562-78.
2000: Arafat W O; Casado E; Wang M; Alvarez R D; Siegal G P; Glorioso J C; Curiel D T; Gómez-Navarro J
Genetically modified CD34+ cells exert a cytotoxic bystander effect on human endothelial and cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4442-8.
2000: Kelly F J; Miller C R; Buchsbaum D J; Gomez-Navarro J; Barnes M N; Alvarez R D; Curiel D T
Selectivity of TAG-72-targeted adenovirus gene transfer to primary ovarian carcinoma cells versus autologous mesothelial cells in vitro.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4323-33.
2000: Alvarez R D; Gomez-Navarro J; Wang M; Barnes M N; Strong T V; Arani R B; Arafat W; Hughes J V; Siegal G P; Curiel D T
Adenoviral-mediated suicide gene therapy for ovarian cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(5):524-30.
2000: Alemany R; Suzuki K; Curiel D T
Blood clearance rates of adenovirus type 5 in mice.
The Journal of general virology 2000;81(Pt 11):2605-9.
2000: Tillman B W; Hayes T L; DeGruijl T D; Douglas J T; Curiel D T
Adenoviral vectors targeted to CD40 enhance the efficacy of dendritic cell-based vaccination against human papillomavirus 16-induced tumor cells in a murine model.
Cancer research 2000;60(19):5456-63.
2000: Arafat W; Gómez-Navarro J; Xiang J; Siegal G P; Alvarez R D; Curiel D T
Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target.
Cancer gene therapy 2000;7(9):1250-6.
2000: Curiel D T
The development of conditionally replicative adenoviruses for cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3395-9.
2000: Curiel D T; Gerritsen W R; Krul M R
Progress in cancer gene therapy.
Cancer gene therapy 2000;7(8):1197-9.
2000: Adachi Y; Reynolds P N; Yamamoto M; Grizzle W E; Overturf K; Matsubara S; Muramatsu T; Curiel D T
Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors.
Cancer research 2000;60(16):4305-10.
2000: Alvarez R D; Barnes M N; Gomez-Navarro J; Wang M; Strong T V; Arafat W; Arani R B; Johnson M R; Roberts B L; Siegal G P; Curiel D T
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(8):3081-7.
2000: Blackwell J L; Li H; Gomez-Navarro J; Dmitriev I; Krasnykh V; Richter C A; Shaw D R; Alvarez R D; Curiel D T; Strong T V
Using a tropism-modified adenoviral vector to circumvent inhibitory factors in ascites fluid.
Human gene therapy 2000;11(12):1657-69.
2000: Dmitriev I; Kashentseva E; Rogers B E; Krasnykh V; Curiel D T
Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells.
Journal of virology 2000;74(15):6875-84.
2000: Alemany R; Balagué C; Curiel D T
Replicative adenoviruses for cancer therapy.
Nature biotechnology 2000;18(7):723-7.
2000: Arafat W O; Gómez-Navarro J; Xiang J; Barnes M N; Mahasreshti P; Alvarez R D; Siegal G P; Badib A O; Buchsbaum D; Curiel D T; Stackhouse M A
An adenovirus encoding proapoptotic Bax induces apoptosis and enhances the radiation effect in human ovarian cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(6):545-54.
2000: Haisma H J; Grill J; Curiel D T; Hoogeland S; van Beusechem V W; Pinedo H M; Gerritsen W R
Targeting of adenoviral vectors through a bispecific single-chain antibody.
Cancer gene therapy 2000;7(6):901-4.
2000: Stackhouse M A; Pederson L C; Grizzle W E; Curiel D T; Gebert J; Haack K; Vickers S M; Mayo M S; Buchsbaum D J
Fractionated radiation therapy in combination with adenoviral delivery of the cytosine deaminase gene and 5-fluorocytosine enhances cytotoxic and antitumor effects in human colorectal and cholangiocarcinoma models.
Gene therapy 2000;7(12):1019-26.
2000: Xiang J; Gómez-Navarro J; Arafat W; Liu B; Barker S D; Alvarez R D; Siegal G P; Curiel D T
Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer.
The journal of gene medicine 2000;2(2):97-106.
2000: Hampton T A; Conry R M; Khazaeli M B; Shaw D R; Curiel D T; LoBuglio A F; Strong T V
SEREX analysis for tumor antigen identification in a mouse model of adenocarcinoma.
Cancer gene therapy 2000;7(3):446-55.
2000: Curiel D T
Rational design of viral vectors based on rigorous analysis of capsid structures.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(1):3-4.
2000: Gómez-Navarro J; Contreras J L; Arafat W; Jiang X L; Krisky D; Oligino T; Marconi P; Hubbard B; Glorioso J C; Curiel D T; Thomas J M
Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model.
Gene therapy 2000;7(1):43-52.
2000: Kasono K; Heike Y; Xiang J; Piché A; Kim H G; Kim M; Hagiwara M; Nawrath M; Moelling K; Curiel D T
Tetracycline-induced expression of an anti-c-Myb single-chain antibody and its inhibitory effect on proliferation of the human leukemia cell line K562.
Cancer gene therapy 2000;7(1):151-9.
2000: Curiel D T
Gene therapy for carcinoma of the breast: Genetic ablation strategies.
Breast cancer research : BCR 2000;2(1):45-9.
1999: Buchsbaum D J; Rogers B E; Khazaeli M B; Mayo M S; Milenic D E; Kashmiri S V; Anderson C J; Chappell L L; Brechbiel M W; Curiel D T
Targeting strategies for cancer radiotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3048s-3055s.
1999: Alemany R; Gomez-Manzano C; Balagué C; Yung W K; Curiel D T; Kyritsis A P; Fueyo J
Gene therapy for gliomas: molecular targets, adenoviral vectors, and oncolytic adenoviruses.
Experimental cell research 1999;252(1):1-12.
1999: Kasono K; Blackwell J L; Douglas J T; Dmitriev I; Strong T V; Reynolds P; Kropf D A; Carroll W R; Peters G E; Bucy R P; Curiel D T; Krasnykh V
Selective gene delivery to head and neck cancer cells via an integrin targeted adenoviral vector.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2571-9.
1999: Curiel D T
Considerations and challenges for the achievement of targeted gene delivery.
Gene therapy 1999;6(9):1497-8.
1999: Haisma H J; Pinedo H M; Rijswijk A; der Meulen-Muileman I; Sosnowski B A; Ying W; Beusechem V W; Tillman B W; Gerritsen W R; Curiel D T
Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM.
Gene therapy 1999;6(8):1469-74.
1999: Thomas F T; Contreras J L; Bilbao G; Ricordi C; Curiel D; Thomas J M
Anoikis, extracellular matrix, and apoptosis factors in isolated cell transplantation.
Surgery 1999;126(2):299-304.
1999: Bilbao G; Contreras J L; Eckhoff D E; Mikheeva G; Krasnykh V; Douglas J T; Thomas F T; Thomas J M; Curiel D T
Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene.
Annals of surgery 1999;230(2):185-93.
1999: Blackwell J L; Miller C R; Douglas J T; Li H; Reynolds P N; Carroll W R; Peters G E; Strong T V; Curiel D T
Retargeting to EGFR enhances adenovirus infection efficiency of squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery 1999;125(8):856-63.
1999: Vanderkwaak T J; Wang M; Gómez-Navarro J; Rancourt C; Dmitriev I; Krasnykh V; Barnes M; Siegal G P; Alvarez R; Curiel D T
An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.
Gynecologic oncology 1999;74(2):227-34.
1999: Bilbao G; Contreras J L; Zhang H G; Pike M J; Overturf K; Mikheeva G; Krasnykh V; Curiel D T
Adenovirus-mediated gene expression in vivo is enhanced by the antiapoptotic bcl-2 gene.
Journal of virology 1999;73(8):6992-7000.
1999: Reynolds P; Dmitriev I; Curiel D
Insertion of an RGD motif into the HI loop of adenovirus fiber protein alters the distribution of transgene expression of the systemically administered vector.
Gene therapy 1999;6(7):1336-9.
1999: Gómez-Navarro J; Curiel D T; Douglas J T
Gene therapy for cancer.
European journal of cancer (Oxford, England : 1990) 1999;35(6):867-85.
1999: Tillman B W; de Gruijl T D; Luykx-de Bakker S A; Scheper R J; Pinedo H M; Curiel T J; Gerritsen W R; Curiel D T
Maturation of dendritic cells accompanies high-efficiency gene transfer by a CD40-targeted adenoviral vector.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6378-83.
1999: Stackhouse M A; Buchsbaum D J; Kancharla S R; Grizzle W E; Grimes C; Laffoon K; Pederson L C; Curiel D T
Specific membrane receptor gene expression targeted with radiolabeled peptide employing the erbB-2 and DF3 promoter elements in adenoviral vectors.
Cancer gene therapy 1999;6(3):209-19.
1999: Douglas J T; Miller C R; Kim M; Dmitriev I; Mikheeva G; Krasnykh V; Curiel D T
A system for the propagation of adenoviral vectors with genetically modified receptor specificities.
Nature biotechnology 1999;17(5):470-5.
1999: Shi Z; Curiel D T; Tang D C
DNA-based non-invasive vaccination onto the skin.
Vaccine 1999;17(17):2136-41.
1999: Bilbao G; Contreras J L; Gómez-Navarro J; Eckhoff D E; Mikheeva G; Krasnykh V; Hynes T; Thomas F T; Thomas J M; Curiel D T
Genetic modification of liver grafts with an adenoviral vector encoding the Bcl-2 gene improves organ preservation.
Transplantation 1999;67(6):775-83.
1999: Bilbao G; Contreras J L; Mikheeva G; Krasnykh V; Eckhoff D E; Thomas F T; Thomas J; Curiel D T
Genetic cytoprotection of human endothelial cells during preservation time with an adenoviral vector encoding the anti-apoptotic human Bcl-2 gene.
Transplantation proceedings 1999;31(1-2):1012-5.
1999: Bilbao G; Zhang H; Contreras J L; Zhou T; Feng M; Saito I; Mountz J D; Curiel D T
Construction of a recombinant adenovirus vector encoding Fas ligand with a CRE/Loxp inducible system.
Transplantation proceedings 1999;31(1-2):792-3.
1999: Rogers B E; McLean S F; Kirkman R L; Della Manna D; Bright S J; Olsen C C; Myracle A D; Mayo M S; Curiel D T; Buchsbaum D J
In vivo localization of [(111)In]-DTPA-D-Phe1-octreotide to human ovarian tumor xenografts induced to express the somatostatin receptor subtype 2 using an adenoviral vector.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(2):383-93.
1999: Reynolds P N; Feng M; Curiel D T
Chimeric viral vectors--the best of both worlds?
Molecular medicine today 1999;5(1):25-31.
1999: Rancourt C; Piché A; Gomez-Navarro J; Wang M; Alvarez R D; Siegal G P; Fuller G M; Jones S A; Curiel D T
Interleukin-6 modulated conditionally replicative adenovirus as an antitumor/cytotoxic agent for cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):43-50.
1999: Curiel D T
Strategies to adapt adenoviral vectors for targeted delivery.
Annals of the New York Academy of Sciences 1999;886():158-71.
1998: Miller C R; Buchsbaum D J; Reynolds P N; Douglas J T; Gillespie G Y; Mayo M S; Raben D; Curiel D T
Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer.
Cancer research 1998;58(24):5738-48.
1998: Dmitriev I; Krasnykh V; Miller C R; Wang M; Kashentseva E; Mikheeva G; Belousova N; Curiel D T
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism.
Journal of virology 1998;72(12):9706-13.
1998: Stackhouse M A; Buchsbaum D J; Grizzle W E; Bright S J; Olsen C C; Kancharla S; Mayo M S; Curiel D T
Radiosensitization mediated by a transfected anti-erbB-2 single-chain antibody in vitro and in vivo.
International journal of radiation oncology, biology, physics 1998;42(4):817-22.
1998: Suzuki T; Piche A; Kasono K; Xiang J; Gomez-Navarro J; Moriuchi S; Krisky D M; Oligino T; Glorioso J C; Curiel T J; Curiel D T
Efficient gene delivery into epstein-barr virus (EBV)-transformed human B cells mediated by replication-defective herpes simplex virus-1 (HSV-1): A gene therapy model for EBV-related B cell malignancy.
Biochemical and biophysical research communications 1998;252(3):686-90.
1998: Zhang H G; Liu D; Heike Y; Yang P; Wang Z; Wang X; Curiel D T; Zhou T; Mountz J D
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells.
Nature biotechnology 1998;16(11):1045-9.
1998: Conry R M; White S A; Fultz P N; Khazaeli M B; Strong T V; Allen K O; Barlow D L; Moore S E; Coan P N; Davis I; Curiel D T; LoBuglio A F
Polynucleotide immunization of nonhuman primates against carcinoembryonic antigen.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2903-12.
1998: Wang M; Rancourt C; Navarro J G; Krisky D; Marconi P; Oligino T; Alvarez R D; Siegal G P; Glorioso J C; Curiel D T
High-efficacy thymidine kinase gene transfer to ovarian cancer cell lines mediated by herpes simplex virus type 1 vector.
Gynecologic oncology 1998;71(2):278-87.
1998: Rancourt C; Rogers B E; Sosnowski B A; Wang M; Piché A; Pierce G F; Alvarez R D; Siegal G P; Douglas J T; Curiel D T
Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2455-61.
1998: Kasono K; Piché A; Xiang J; Kim H G; Bilbao G; Johanning F; Nawrath M; Moelling K; Curiel D T
Functional knock-out of c-myb by an intracellular anti-c-Myb single-chain antibody.
Biochemical and biophysical research communications 1998;251(1):124-30.
1998: Piché A; Kasono K; Johanning F; Curiel T J; Curiel D T
Phenotypic knock-out of the latent membrane protein 1 of Epstein-Barr virus by an intracellular single-chain antibody.
Gene therapy 1998;5(9):1171-9.
1998: Robertson M W; Wang M; Siegal G P; Rosenfeld M; Ashford R S; Alvarez R D; Garver R I; Curiel D T
Use of a tissue-specific promoter for targeted expression of the herpes simplex virus thymidine kinase gene in cervical carcinoma cells.
Cancer gene therapy 1998;5(5):331-6.
1998: Grim J E; Siegal G P; Alvarez R D; Curiel D T
Intracellular expression of the anti-erbB-2 sFv N29 fails to accomplish efficient target modulation.
Biochemical and biophysical research communications 1998;250(3):699-703.
1998: Zhang H G; Zhou T; Yang P; Edwards C K; Curiel D T; Mountz J D
Inhibition of tumor necrosis factor alpha decreases inflammation and prolongs adenovirus gene expression in lung and liver.
Human gene therapy 1998;9(13):1875-84.
1998: Goldsmith K T; Dion L D; Curiel D T; Garver R I
trans E1 component requirements for maximal replication of E1-defective recombinant adenovirus.
Virology 1998;248(2):406-19.
1998: Smith B F; Baker H J; Curiel D T; Jiang W; Conry R M
Humoral and cellular immune responses of dogs immunized with a nucleic acid vaccine encoding human carcinoembryonic antigen.
Gene therapy 1998;5(7):865-8.
1998: Goldman C K; Kendall R L; Cabrera G; Soroceanu L; Heike Y; Gillespie G Y; Siegal G P; Mao X; Bett A J; Huckle W R; Thomas K A; Curiel D T
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8795-800.
1998: Zinn K R; Douglas J T; Smyth C A; Liu H G; Wu Q; Krasnykh V N; Mountz J D; Curiel D T; Mountz J M
Imaging and tissue biodistribution of 99mTc-labeled adenovirus knob (serotype 5).
Gene therapy 1998;5(6):798-808.
1998: Robertson M W; Barnes M N; Rancourt C; Wang M; Grim J; Alvarez R D; Siegal G P; Curiel D T
Gene therapy for ovarian carcinoma.
Seminars in oncology 1998;25(3):397-406.
1998: Pederson L C; Vickers S M; Buchsbaum D J; Kancharla S R; Mayo M S; Curiel D T; Stackhouse M A
Combined cytosine deaminase expression, 5-fluorocytosine exposure, and radiotherapy increases cytotoxicity to cholangiocarcinoma cells.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 1998;2(3):283-91.
1998: Grim J; Deshane J; Siegal G P; Alvarez R D; DiFiore P; Curiel D T
The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv.
Journal of molecular medicine (Berlin, Germany) 1998;76(6):451-8.
1998: Campain J A; Matassa A A; Felgner P L; Barnhart K M; Curiel D T; Harrison G S
Lipid- and adenoviral-mediated gene transfer into AIDS-Kaposi's sarcoma cell lines.
Cancer gene therapy 1998;5(3):131-43.
1998: Piché A; Grim J; Rancourt C; Gómez-Navarro J; Reed J C; Curiel D T
Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7.
Cancer research 1998;58(10):2134-40.
1998: Wang-Johanning F; Gillespie G Y; Grim J; Rancourt C; Alvarez R D; Siegal G P; Curiel D T
Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects.
Cancer research 1998;58(9):1893-900.
1998: Gómez-Navarro J; Siegal G P; Alvarez R D; Curiel D T
Gene therapy: ovarian carcinoma as the paradigm.
American journal of clinical pathology 1998;109(4):444-67.
1998: Zhang H G; Bilbao G; Zhou T; Contreras J L; Gómez-Navarro J; Feng M; Saito I; Mountz J D; Curiel D T
Application of a Fas ligand encoding a recombinant adenovirus vector for prolongation of transgene expression.
Journal of virology 1998;72(3):2483-90.
1998: Krasnykh V; Dmitriev I; Mikheeva G; Miller C R; Belousova N; Curiel D T
Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob.
Journal of virology 1998;72(3):1844-52.
1998: Rancourt C; Robertson M W; Wang M; Goldman C K; Kelly J F; Alvarez R D; Siegal G P; Curiel D T
Endothelial cell vehicles for delivery of cytotoxic genes as a gene therapy approach for carcinoma of the ovary.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):265-70.
1997: Rogers B E; Douglas J T; Ahlem C; Buchsbaum D J; Frincke J; Curiel D T
Use of a novel cross-linking method to modify adenovirus tropism.
Gene therapy 1997;4(12):1387-92.
1997: Curiel T J; Piché A; Kasono K; Curiel D T
Gene therapy strategies for AIDS-related malignancies.
Gene therapy 1997;4(12):1284-8.
1997: Rogers B E; Curiel D T; Mayo M S; Laffoon K K; Bright S J; Buchsbaum D J
Tumor localization of a radiolabeled bombesin analogue in mice bearing human ovarian tumors induced to express the gastrin-releasing peptide receptor by an adenoviral vector.
Cancer 1997;80(12 Suppl):2419-24.
1997: Tang D C; Jennelle R S; Shi Z; Garver R I; Carbone D P; Loya F; Chang C H; Curiel D T
Overexpression of adenovirus-encoded transgenes from the cytomegalovirus immediate early promoter in irradiated tumor cells.
Human gene therapy 1997;8(17):2117-24.
1997: Pederson L C; Buchsbaum D J; Vickers S M; Kancharla S R; Mayo M S; Curiel D T; Stackhouse M A
Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo.
Cancer research 1997;57(19):4325-32.
1997: Feng M; Jackson W H; Goldman C K; Rancourt C; Wang M; Dusing S K; Siegal G; Curiel D T
Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector.
Nature biotechnology 1997;15(9):866-70.
1997: Vickers S M; Sampson L S; Phillips J O; Eckhoff D; Kerby J D; Sekar M C; Curiel D T; Thompson J A
Adenoviral vector infection of the human exocrine pancreas.
Archives of surgery (Chicago, Ill. : 1960) 1997;132(9):1006-9.
1997: Rogers B E; Rosenfeld M E; Khazaeli M B; Mikheeva G; Stackhouse M A; Liu T; Curiel D T; Buchsbaum D J
Localization of iodine-125-mIP-Des-Met14-bombesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(8):1221-9.
1997: Rosenfeld M E; Rogers B E; Khazaeli M B; Mikheeva G; Raben D; Mayo M S; Curiel D T; Buchsbaum D J
Adenoviral-mediated delivery of gastrin-releasing peptide receptor results in specific tumor localization of a bombesin analogue in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(7):1187-94.
1997: Douglas J T; Curiel D T
Strategies to accomplish targeted gene delivery to muscle cells employing tropism-modified adenoviral vectors.
Neuromuscular disorders : NMD 1997;7(5):284-98.
1997: Bilbao G; Feng M; Rancourt C; Jackson W H; Curiel D T
Adenoviral/retroviral vector chimeras: a novel strategy to achieve high-efficiency stable transduction in vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(8):624-34.
1997: Ruppert J M; Wright M; Rosenfeld M; Grushcow J; Bilbao G; Curiel D T; Strong T V
Gene therapy strategies for carcinoma of the breast.
Breast cancer research and treatment 1997;44(2):93-114.
1997: Strong T V; Hampton T A; Louro I; Bilbao G; Conry R M; Curiel D T
Incorporation of beta-globin untranslated regions into a Sindbis virus vector for augmentation of heterologous mRNA expression.
Gene therapy 1997;4(6):624-7.
1997: Rosenfeld M E; Vickers S M; Raben D; Wang M; Sampson L; Feng M; Jaffee E; Curiel D T
Pancreatic carcinoma cell killing via adenoviral mediated delivery of the herpes simplex virus thymidine kinase gene.
Annals of surgery 1997;225(5):609-18; discussion 618-20.
1997: Goldman C K; Soroceanu L; Smith N; Gillespie G Y; Shaw W; Burgess S; Bilbao G; Curiel D T
In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer.
Nature biotechnology 1997;15(5):462-6.
1997: McDaniel L S; Loechel F; Benedict C; Greenway T; Briles D E; Conry R M; Curiel D T
Immunization with a plasmid expressing pneumococcal surface protein A (PspA) can elicit protection against fatal infection with Streptococcus pneumoniae.
Gene therapy 1997;4(4):375-7.
1997: Wright M; Grim J; Deshane J; Kim M; Strong T V; Siegal G P; Curiel D T
An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2.
Gene therapy 1997;4(4):317-22.
1997: Goldman C K; Rogers B E; Douglas J T; Sosnowski B A; Ying W; Siegal G P; Baird A; Campain J A; Curiel D T
Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor.
Cancer research 1997;57(8):1447-51.
1997: Deshane J; Siegal G P; Wang M; Wright M; Bucy R P; Alvarez R D; Curiel D T
Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy.
Gynecologic oncology 1997;64(3):378-85.
1997: Kim M; Wright M; Deshane J; Accavitti M A; Tilden A; Saleh M; Vaughan W P; Carabasi M H; Rogers M D; Hockett R D; Grizzle W E; Curiel D T
A novel gene therapy strategy for elimination of prostate carcinoma cells from human bone marrow.
Human gene therapy 1997;8(2):157-70.
1997: Barnes M N; Deshane J S; Rosenfeld M; Siegal G P; Curiel D T; Alvarez R D
Gene therapy and ovarian cancer: a review.
Obstetrics and gynecology 1997;89(1):145-55.
1997: Curiel D T
Targeted tumor cytotoxicity mediated by intracellular single-chain anti-oncogene antibodies.
Advances in pharmacology (San Diego, Calif.) 1997;40():51-84.
1996: Buchsbaum D J; Raben D; Stackhouse M A; Khazaeli M B; Rogers B E; Rosenfeld M E; Liu T; Curiel D T
Approaches to enhance cancer radiotherapy employing gene transfer methods.
Gene therapy 1996;3(12):1042-68.
1996: Douglas J T; Rogers B E; Rosenfeld M E; Michael S I; Feng M; Curiel D T
Targeted gene delivery by tropism-modified adenoviral vectors.
Nature biotechnology 1996;14(11):1574-8.
1996: Dion L D; Goldsmith K T; Strong T V; Bilbao G; Curiel D T; Garver R I
E1A RNA transcripts amplify adenovirus-mediated tumor reduction.
Gene therapy 1996;3(11):1021-5.
1996: Krasnykh V N; Mikheeva G V; Douglas J T; Curiel D T
Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.
Journal of virology 1996;70(10):6839-46.
1996: Vickers S M; Phillips J O; Kerby J D; Bynon J S; Thompson J A; Curiel D T
In vivo gene transfer to the human biliary tract.
Gene therapy 1996;3(9):825-8.
1996: Grim J; Deshane J; Feng M; Lieber A; Kay M; Curiel D T
erbB-2 knockout employing an intracellular single-chain antibody (sFv) accomplishes specific toxicity in erbB-2-expressing lung cancer cells.
American journal of respiratory cell and molecular biology 1996;15(3):348-54.
1996: Rosenfeld M E; Wang M; Siegal G P; Alvarez R D; Mikheeva G; Krasnykh V; Curiel D T
Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma.
Journal of molecular medicine (Berlin, Germany) 1996;74(8):455-62.
1996: Zeigler S T; Kerby J D; Curiel D T; Wehby J N; Diethelm A G; Thompson J A
Molecular conjugate-mediated gene transfer in renal transplantation.
Transplantation proceedings 1996;28(4):2046-8.
1996: Barnes M N; Deshane J S; Siegal G P; Alvarez R D; Curiel D T
Novel gene therapy strategy to accomplish growth factor modulation induces enhanced tumor cell chemosensitivity.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(7):1089-95.
1996: Raben D; Buchsbaum D J; Khazaeli M B; Rosenfeld M E; Gillespie G Y; Grizzle W E; Liu T; Curiel D T
Enhancement of radiolabeled antibody binding and tumor localization through adenoviral transduction of the human carcinoembryonic antigen gene.
Gene therapy 1996;3(7):567-80.
1996: Ebbinghaus S W; Vigneswaran N; Miller C R; Chee-Awai R A; Mayfield C A; Curiel D T; Miller D M
Efficient delivery of triplex forming oligonucleotides to tumor cells by adenovirus-polylysine complexes.
Gene therapy 1996;3(4):287-97.
1996: Deshane J; Grim J; Loechel S; Siegal G P; Alvarez R D; Curiel D T
Intracellular antibody against erbB-2 mediates targeted tumor cell eradication by apoptosis.
Cancer gene therapy 1996;3(2):89-98.
1996: Zeigler S T; Kerby J D; Curiel D T; Diethelm A G; Thompson J A
Molecular conjugate-mediated gene transfer into isolated human kidneys.
Transplantation 1996;61(5):812-7.
1996: Conry R M; LoBuglio A F; Curiel D T
Polynucleotide-mediated immunization therapy of cancer.
Seminars in oncology 1996;23(1):135-47.
1996: Conry R M; Widera G; LoBuglio A F; Fuller J T; Moore S E; Barlow D L; Turner J; Yang N S; Curiel D T
Selected strategies to augment polynucleotide immunization.
Gene therapy 1996;3(1):67-74.
1996: Rosenfeld M E; Curiel D T
Gene therapy strategies for novel cancer therapeutics.
Current opinion in oncology 1996;8(1):72-7.
1996: Curiel D T; Pilewski J M; Albelda S M
Gene therapy approaches for inherited and acquired lung diseases.
American journal of respiratory cell and molecular biology 1996;14(1):1-18.
1995: Rosenfeld M E; Feng M; Michael S I; Siegal G P; Alvarez R D; Curiel D T
Adenoviral-mediated delivery of the herpes simplex virus thymidine kinase gene selectively sensitizes human ovarian carcinoma cells to ganciclovir.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1571-80.
1995: Deshane J; Siegal G P; Alvarez R D; Wang M H; Feng M; Cabrera G; Liu T; Kay M; Curiel D T
Targeted tumor killing via an intracellular antibody against erbB-2.
The Journal of clinical investigation 1995;96(6):2980-9.
1995: Michael S I; Hong J S; Curiel D T; Engler J A
Addition of a short peptide ligand to the adenovirus fiber protein.
Gene therapy 1995;2(9):660-8.
1995: Deshane J; Cabrera G; Grim J E; Siegal G P; Pike J; Alvarez R D; Curiel D T
Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody.
Gynecologic oncology 1995;59(1):8-14.
1995: Johanning F W; Conry R M; LoBuglio A F; Wright M; Sumerel L A; Pike M J; Curiel D T
A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo.
Nucleic acids research 1995;23(9):1495-501.
1995: Feng M; Cabrera G; Deshane J; Scanlon K J; Curiel D T
Neoplastic reversion accomplished by high efficiency adenoviral-mediated delivery of an anti-ras ribozyme.
Cancer research 1995;55(10):2024-8.
1995: Conry R M; LoBuglio A F; Wright M; Sumerel L; Pike M J; Johanning F; Benjamin R; Lu D; Curiel D T
Characterization of a messenger RNA polynucleotide vaccine vector.
Cancer research 1995;55(7):1397-400.
1995: Conry R M; LoBuglio A F; Loechel F; Moore S E; Sumerel L A; Barlow D L; Pike J; Curiel D T
A carcinoembryonic antigen polynucleotide vaccine for human clinical use.
Cancer gene therapy 1995;2(1):33-8.
1995: Conry R M; LoBuglio A F; Loechel F; Moore S E; Sumerel L A; Barlow D L; Curiel D T
A carcinoembryonic antigen polynucleotide vaccine has in vivo antitumor activity.
Gene therapy 1995;2(1):59-65.
1994: Lu D; Benjamin R; Kim M; Conry R M; Curiel D T
Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors.
Cancer gene therapy 1994;1(4):245-52.
1994: Goldsmith K T; Curiel D T; Engler J A; Garver R I
Trans complementation of an E1A-deleted adenovirus with codelivered E1A sequences to make recombinant adenoviral producer cells.
Human gene therapy 1994;5(11):1341-8.
1994: Deshane J; Loechel F; Conry R M; Siegal G P; King C R; Curiel D T
Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines.
Gene therapy 1994;1(5):332-7.
1994: Michael S I; Curiel D T
Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway.
Gene therapy 1994;1(4):223-32.
1994: Curiel D T
High-efficiency gene transfer mediated by adenovirus-polylysine-DNA complexes.
Annals of the New York Academy of Sciences 1994;716():36-56; discussion 56-8.
1994: Curiel D T
High-efficiency gene transfer employing adenovirus-polylysine-DNA complexes.
Natural immunity 1994;13(2-3):141-64.
1994: Conry R M; LoBuglio A F; Kantor J; Schlom J; Loechel F; Moore S E; Sumerel L A; Barlow D L; Abrams S; Curiel D T
Immune response to a carcinoembryonic antigen polynucleotide vaccine.
Cancer research 1994;54(5):1164-8.
1994: Curiel T J; Cook D R; Bogedain C; Jilg W; Harrison G S; Cotten M; Curiel D T; Wagner E
Efficient foreign gene expression in Epstein-Barr virus-transformed human B-cells.
Virology 1994;198(2):577-85.
1994: Smith M J; Rousculp M D; Goldsmith K T; Curiel D T; Garver R I
Surfactant protein A-directed toxin gene kills lung cancer cells in vitro.
Human gene therapy 1994;5(1):29-35.
1994: Garver R I; Goldsmith K T; Rodu B; Hu P C; Sorscher E J; Curiel D T
Strategy for achieving selective killing of carcinomas.
Gene therapy 1994;1(1):46-50.
1994: Cook D R; Maxwell I H; Glode L M; Maxwell F; Stevens J O; Purner M B; Wagner E; Curiel D T; Curiel T J
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
Cancer biotherapy 1994;9(2):131-41.

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