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David Curiel

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Dong Chen; David T Curiel; Igor Dmitriev; Luni Emdad; Paul B Fisher; Rachel Gredler; Elena A Kashentseva; Devaraja Rajasekaran; Chadia L Robertson; Prasanna K. Santhekadur; Xue-Ning Shen; Ayesha Siddiq; Jyoti Srivastava; Devanand Sarkar
Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC).
Julius W Kim; Masaharu Nakayama; Hideyo Ugai; Ferhat Ak; Joel N Glasgow; David T Curiel
An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer.
Hideyo Ugai; Minghui Wang; George C Dobbins; Long P Le; David A Matthews; David T Curiel
Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1.

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All Publications

2013: Dong Chen; David T Curiel; Igor Dmitriev; Luni Emdad; Paul B Fisher; Rachel Gredler; Elena A Kashentseva; Devaraja Rajasekaran; Chadia L Robertson; Prasanna K. Santhekadur; Xue-Ning Shen; Ayesha Siddiq; Jyoti Srivastava; Devanand Sarkar
Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC).
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(4):758-66.
2013: Julius W Kim; Masaharu Nakayama; Hideyo Ugai; Ferhat Ak; Joel N Glasgow; David T Curiel
An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer.
PloS one 2013;8(2):e55533.
2012: Hideyo Ugai; Minghui Wang; George C Dobbins; Long P Le; David A Matthews; David T Curiel
Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1.
Virology 2012;432(2):283-95.
2012: Quyen D Chu; David T Curiel; Roger Kim; Benjamin D L Li; Natalia Luraguiz; Matt Pope; Guang Sun; J Michael Mathis
Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model.
Surgery 2012;152(3):441-8.
2012: Basav N Hangalapura; Dinja Oosterhoff; Rik J Scheper; Laura Timares; David T Curiel; Tanja D de Gruijl
CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic.
The journal of gene medicine 2012;14(6):416-27.
2012: Belal Azab; Sujit K Bhutia; David T Curiel; Swadesh K Das; Rupesh Dash; Paul Dent; Igor P Dmitriev; Steven Grant; Michael Hedvat; Maurizio Pellecchia; Bridget A Quinn; John C Reed; Devanand Sarkar; Siddik Sarkar; Xue-Ning Shen; Xiang-Yang Wang; Paul B Fisher
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
Journal of cellular physiology 2012;227(5):2145-53.
2012: Sujit K Bhutia; David T Curiel; Swadesh K Das; Rupesh Dash; Paul Dent; Steven Grant; Timothy P Kegelman; Seok-Geun Lee; Federica Rizzi; Devanand Sarkar; Zhao-Zhong Su; Xiang-Yang Wang; Belal Azab; Saverio Bettuzzi; Paul B Fisher
mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer.
Journal of cellular physiology 2012;227(5):1805-13.
2012: Briana Jill Williams; Alexander V Pereboev; Donna L Rogers; Lisa K Adams; Shilpa Bhatia; Susan Boling; Jennifer L Carroll; David T Curiel; Nikolay Korokhov; Imre Kovesdi; Xiao-Lin Li; J Michael Mathis
Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector.
PloS one 2012;7(10):e46981.
2012: Matthew S Beatty; David T Curiel
Chapter two--Adenovirus strategies for tissue-specific targeting.
Advances in cancer research 2012;115():39-67.
2012: Michael O Alberti; Edward Abraham; Stanton L Gerson; Mourad Ismail; Larisa Pereboeva; Justin Roth; Yuko Tsuruta; David T Curiel
Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation.
PloS one 2012;7(5):e37812.
2011: Bridget A Quinn; Mohamed Rahmani; John C Reed; Devanand Sarkar; Siddik Sarkar; John L Stebbins; Jun Wei; Bainan Wu; Belal Azab; David T Curiel; Swadesh K Das; Santanu Dasgupta; Rupesh Dash; Paul Dent; Igor Dmitriev; Steven Grant; Michael Hedvat; Sachin Kumar; Regina A Oyesanya; Maurizio Pellecchia; Paul B Fisher
Targeting Mcl-1 for the therapy of cancer.
Expert opinion on investigational drugs 2011;20(10):1397-411.
2011: Daniel T Rein; Anne Volkmer; Stephan E Baldus; Gerd J Bauerschmitz; Ines M Beyer; David T Curiel; Anca Dragoi; Alexandra P Hess; Wolfgang Janni; Nicolai Maass; Martina Breidenbach
Treatment of chemotherapy resistant ovarian cancer with a MDR1 targeted oncolytic adenovirus.
Gynecologic oncology 2011;123(1):138-46.
2011: Basav N Hangalapura; Dinja Oosterhoff; Alexander Pereboev; Rik J Scheper; Thomas Tüting; Victor W van Beusechem; Alfons J van den Eertwegh; Louis Boon; David T Curiel; Jan de Groot; Winald Gerritsen; Tanja D de Gruijl
Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine.
Cancer research 2011;71(17):5827-37.
2011: Paul Dent; David T Curiel; Paul B Fisher
The potential of virus-based gene therapies for treatment of metastatic kidney cancer.
Expert review of anticancer therapy 2011;11(6):809-11.
2011: Rupesh Dash; Belal Azab; Bridget A Quinn; Xuening Shen; Xiang-Yang Wang; Swadesh K Das; Mohamed Rahmani; Jun Wei; Michael Hedvat; Paul Dent; Igor P Dmitriev; David T Curiel; Steven Grant; Bainan Wu; John L Stebbins; Maurizio Pellecchia; John C Reed; Devanand Sarkar; Paul B Fisher
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8785-90.
2011: Ann Marie O'Neill; Annette N Smith; Elizabeth A Spangler; Elizabeth M Whitley; Stephanie E Schleis; Richard C Bird; David T Curiel; Erin E Thacker; Bruce F Smith
Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins.
Cancer biology & therapy 2011;11(7):651-8.
2011: Basav N Hangalapura; Dinja Oosterhoff; Tarun Gupta; Jan de Groot; Pepijn G J T B Wijnands; Victor W van Beusechem; Joke M M den Haan; Thomas Tüting; Alfons J M van den Eertwegh; David T Curiel; Rik J Scheper; Tanja D de Gruijl
Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine.
Vaccine 2011;29(12):2313-21.
2011: Margaret A Park; Hossein A Hamed; Clint Mitchell; Nichola Cruickshanks; Rupesh Dash; Jeremy C Allegood; Igor P Dmitriev; Gary Tye; Besim Ogretmen; Sarah Spiegel; Adly Yacoub; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Molecular pharmacology 2011;79(3):368-80.
2011: Rupesh Dash; Belal Azab; Xue-Ning Shen; Upneet K Sokhi; Siddik Sarkar; Zhao-zhong Su; Xiang-Yang Wang; Pier Paolo Claudio; Paul Dent; Igor P Dmitriev; David T Curiel; Steven Grant; Devanand Sarkar; Paul B Fisher
Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic.
Discovery medicine 2011;11(56):46-56.
2010: Patrick J Eulitt; Margaret A Park; Hamed Hossein; Nichola Cruikshanks; Chen Yang; Igor P Dmitriev; Adly Yacoub; David T Curiel; Paul B Fisher; Paul Dent
Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery.
Cancer biology & therapy 2010;10(12):1290-305.
2010: Mohamed Rahmani; Mandy Mayo; Rupesh Dash; Upneet Kaur Sokhi; Igor P Dmitriev; Devanand Sarkar; Paul Dent; David T Curiel; Paul B Fisher; Steven Grant
Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.
Molecular pharmacology 2010;78(6):1096-104.
2010: Miho Murakami; Hideyo Ugai; Minghui Wang; Natalya Belousova; Paul Dent; Paul B Fisher; Joel N Glasgow; Maaike Everts; David T Curiel
An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations.
Virology 2010;407(2):196-205.
2010: Paul Dent; Adly Yacoub; Hossein A Hamed; Margaret A Park; Rupesh Dash; Sujit K Bhutia; Devanand Sarkar; Xiang-Yang Wang; Pankaj Gupta; Luni Emdad; Irina V Lebedeva; Moira Sauane; Zao-Zhong Su; Mohamed Rahmani; William C Broaddus; Harold F Young; Maciej S Lesniak; Steven Grant; David T Curiel; Paul B Fisher
The development of MDA-7/IL-24 as a cancer therapeutic.
Pharmacology & therapeutics 2010;128(2):375-84.
2010: Rupesh Dash; Sujit K Bhutia; Belal Azab; Zao-Zhong Su; Bridget A Quinn; Timothy P Kegelmen; Swadesh K Das; Keetae Kim; Seok-Geun Lee; Margaret A Park; Adly Yacoub; Mohammed Rahmani; Luni Emdad; Igor P Dmitriev; Xiang-Yang Wang; Devanand Sarkar; Steven Grant; Paul Dent; David T Curiel; Paul B Fisher
mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.
Cytokine & growth factor reviews 2010;21(5):381-91.
2010: Krista Pennington; Quyen D Chu; David T Curiel; Benjamin D L Li; J Michael Mathis
The utility of a tissue slice model system to determine breast cancer infectivity by oncolytic adenoviruses.
The Journal of surgical research 2010;163(2):270-5.
2010: Basav N Hangalapura; Dinja Oosterhoff; Shikhar Aggarwal; Pepijn G J T B Wijnands; Rieneke van de Ven; Saskia J A M Santegoets; M Petrousjka van den Tol; Erik Hooijberg; Alexander Pereboev; Alfons J M van den Eertwegh; David T Curiel; Rik J Scheper; Tanja D de Gruijl
Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(7):706-15.
2010: Paul Dent; Adly Yacoub; Hossein A Hamed; Margaret A Park; Rupesh Dash; Sujit K Bhutia; Devanand Sarkar; Pankaj Gupta; Luni Emdad; Irina V Lebedeva; Moira Sauane; Zao-Zhong Su; Mohamed Rahmani; William C Broaddus; Harold F Young; Maciej Lesniak; Steven Grant; David T Curiel; Paul B Fisher
MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.
Anti-cancer drugs 2010;21(8):725-31.
2010: A A V Paupoo; Zeng B Zhu; Minghui Wang; Daniel T Rein; A Starzinski-Powitz; David T Curiel
A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effect.
Human reproduction (Oxford, England) 2010;25(8):2068-83.
2010: R Dash; I Dmitriev; Zao-Zhong Su; S K Bhutia; B Azab; N Vozhilla; Adly Yacoub; Paul Dent; David T Curiel; Devanand Sarkar; Paul B Fisher
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells.
Cancer gene therapy 2010;17(7):447-56.
2010: Hossein A Hamed; Adly Yacoub; Margaret A Park; Patrick J Eulitt; Rupesh Dash; Devanand Sarkar; Igor P Dmitriev; Maciej S Lesniak; Khalid Shah; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(6):1130-42.
2010: Daniel T Rein; Torsten Schmidt; Gerd Bauerschmitz; Monika Hampl; Ines M Beyer; Arasen A V Paupoo; David T Curiel; Martina Breidenbach
Treatment of endometriosis with a VEGF-targeted conditionally replicative adenovirus.
Fertility and sterility 2010;93(8):2687-94.
2010: Sujit K Bhutia; Rupesh Dash; Swadesh K Das; Belal Azab; Zao-Zhong Su; Seok-Geun Lee; Steven Grant; Adly Yacoub; Paul Dent; David T Curiel; Devanand Sarkar; Paul B Fisher
Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24.
Cancer research 2010;70(9):3667-76.
2010: Anton V Borovjagin; Lacey R McNally; Minghui Wang; David T Curiel; Mary J MacDougall; Kurt R Zinn
Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging.
Molecular imaging 2010;9(2):59-75.
2010: Hossein A Hamed; Adly Yacoub; Margaret A Park; Patrick Eulitt; Devanand Sarkar; Igor P Dimitrie; Ching-Shih Chen; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins.
Cancer biology & therapy 2010;9(7):526-36.
2010: Miho Murakami; Hideyo Ugai; Natalya Belousova; Alexander Pereboev; Paul Dent; Paul B Fisher; Maaike Everts; David T Curiel
Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.
The Prostate 2010;70(4):362-76.
2010: Adly Yacoub; Hossein A Hamed; Jeremy C Allegood; Clint Mitchell; Sarah Spiegel; Maciej S Lesniak; Besim Ogretmen; Rupesh Dash; Devanand Sarkar; William C Broaddus; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.
Cancer research 2010;70(3):1120-9.
2010: Adly Yacoub; Renyan Liu; Margaret A Park; Hossein A Hamed; Rupesh Dash; Danielle N Schramm; Devanand Sarkar; Igor P Dimitriev; Jessica K Bell; Steven Grant; Nicholas P Farrell; David T Curiel; Paul B Fisher; Paul Dent
Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
Molecular pharmacology 2010;77(2):298-310.
2010: Hideyo Ugai; Minghui Wang; Long P Le; David A Matthews; Masato Yamamoto; David T Curiel
In vitro dynamic visualization analysis of fluorescently labeled minor capsid protein IX and core protein V by simultaneous detection.
Journal of molecular biology 2010;395(1):55-78.
2010: Travis B Lewis; Joel N Glasgow; Anya M Glandon; David T Curiel; David G Standaert
Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy.
PloS one 2010;5(9):.
2010: Qiana L Matthews; Aiman Fatima; Yizhe Tang; Brian A Perry; Yuko Tsuruta; Svetlana Komarova; Laura Timares; Chunxia Zhao; Natalia Makarova; Anton V Borovjagin; Phoebe L Stewart; Hongju Wu; Jerry L Blackwell; David T Curiel
HIV antigen incorporation within adenovirus hexon hypervariable 2 for a novel HIV vaccine approach.
PloS one 2010;5(7):e11815.
2010: Svetlana Komarova; Justin Roth; Ronald Alvarez; David T Curiel; Larisa Pereboeva
Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor.
Journal of ovarian research 2010;3():12.
2010: Jing Li; Aiman Fatima; Svetlana Komarova; Hideyo Ugai; Priyanka Uprety; Justin C Roth; Minghui Wang; Robert A Oster; David T Curiel; Qiana L Matthews
Evaluation of adenovirus capsid labeling versus transgene expression.
Virology journal 2010;7():21.
2009: Paul Dent; David T Curiel; Steven Grant; Paul B Fisher
Minting a new class of polo-like-kinase inhibitors.
Cancer biology & therapy 2009;8(24):2384-5.
2009: Erin E Thacker; Masaharu Nakayama; Bruce F Smith; R Curtis Bird; Zhanat Muminova; Theresa V Strong; Laura Timares; Nikolay Korokhov; Ann Marie O'Neill; Tanja D de Gruijl; Joel N Glasgow; Kenzaburo Tani; David T Curiel
A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo.
Vaccine 2009;27(50):7116-24.
2009: Junji Uchino; Koichi Takayama; Akiko Harada; Yosuke Kawakami; Hiroyuki Inoue; David T Curiel; Yoichi Nakanishi
[hTERT promoter-based conditionally replicative adenoviruses are useful for lung cancer and other solid cancer treatment].
Fukuoka igaku zasshi = Hukuoka acta medica 2009;100(11):338-48.
2009: Rieneke van de Ven; Jelle J Lindenberg; Dinja Oosterhoff; M Petrousjka van den Tol; Rodney A Rosalia; Miho Murakami; Maaike Everts; George L Scheffer; Rik J Scheper; Tanja D de Gruijl; David T Curiel
Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(9):895-906.
2009: Amy R Nelson; Julia Davydova; David T Curiel; Masato Yamamoto
Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer.
Cancer science 2009;100(11):2181-7.
2009: Ana J Pérez-Berná; Roberto Marabini; Sjors H W Scheres; Rosa Menéndez-Conejero; Igor P Dmitriev; David T Curiel; Walter F Mangel; S Jane Flint; Carmen San Martín
Structure and uncoating of immature adenovirus.
Journal of molecular biology 2009;392(2):547-57.
2009: Kristopher J Kimball; Angel A Rivera; Kurt R Zinn; Mert Icyuz; Vaibhav Saini; Jing Li; Zeng B Zhu; Gene P Siegal; Joanne T Douglas; David T Curiel; Ronald D Alvarez; Anton V Borovjagin
Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.
Molecular imaging 2009;8(5):264-77.
2009: Kellie S Matthews; Ronald D Alvarez; David T Curiel
Advancements in adenoviral based virotherapy for ovarian cancer.
Advanced drug delivery reviews 2009;61(10):836-41.
2009: Joshua J Short; David T Curiel
Oncolytic adenoviruses targeted to cancer stem cells.
Molecular cancer therapeutics 2009;8(8):2096-102.
2009: Kellie Matthews; Patricia E Noker; Baohong Tian; Sheila D Grimes; Ronna Fulton; Karen Schweikart; Raymond Harris; Rose Aurigemma; Minghui Wang; Mack N Barnes; Gene P Siegal; Akseli Hemminki; Kurt Zinn; David T Curiel; Ronald D Alvarez
Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4131-7.
2009: Paul Dent; David T Curiel; Paul B Fisher; Steven Grant
Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2009;12(3):65-73.
2009: Elena Kashentseva; Joanne T Douglas; Kurt R Zinn; David T Curiel; Igor Dmitriev
Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody.
Journal of molecular biology 2009;388(3):443-61.
2009: Margaret A Park; Teneille Walker; Aditi Pandya Martin; Jeremy C Allegood; Nicollaq Vozhilla; Luni Emdad; Devanand Sarkar; Mohamed Rahmani; Martin Graf; Adly Yacoub; Constantinos Koumenis; Sarah Spiegel; David T Curiel; Christina Voelkel Johnson; Steven Grant; Paul B Fisher; Paul Dent
MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.
Molecular cancer therapeutics 2009;8(5):1280-91.
2009: Alexander Stoff; Angel A Rivera; N Sanjib Banerjee; Steven T Moore; T Michael Numnum; Antonio Espinosa-de-los-Monteros; Dirk F Richter; Gene P Siegal; Louise T Chow; Dale Feldman; Luis O Vasconez; J Michael Mathis; Mariam A Stoff-Khalili; David T Curiel
Promotion of incisional wound repair by human mesenchymal stem cell transplantation.
Experimental dermatology 2009;18(4):362-9.
2009: Hua-Jung Li; Maaike Everts; Masato Yamamoto; David T Curiel; Harvey R Herschman
Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors.
Cancer research 2009;69(2):554-64.
2009: Yizhe Tang; Hongju Wu; Hideyo Ugai; Qiana L Matthews; David T Curiel
Derivation of a triple mosaic adenovirus for cancer gene therapy.
PloS one 2009;4(12):e8526.
2009: Joel N Glasgow; Galina Mikheeva; Victor Krasnykh; David T Curiel
A strategy for adenovirus vector targeting with a secreted single chain antibody.
PloS one 2009;4(12):e8355.
2009: Paul Dent; Steven Grant; Paul B Fisher; David T Curiel
PI3K: A rational target for ovarian cancer therapy?
Cancer biology & therapy 2009;8(1):27-30.
2008: Carmen San Martín; Joel N Glasgow; Anton Borovjagin; Matthew S Beatty; Elena A Kashentseva; David T Curiel; Roberto Marabini; Igor P Dmitriev
Localization of the N-terminus of minor coat protein IIIa in the adenovirus capsid.
Journal of molecular biology 2008;383(4):923-34.
2008: Rieneke van de Ven; George L Scheffer; Anneke W Reurs; Jelle J Lindenberg; Ruud Oerlemans; Gerrit Jansen; Jean-Pierre Gillet; Joel N Glasgow; Alexander Pereboev; David T Curiel; Rik J Scheper; Tanja D de Gruijl
A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration.
Blood 2008;112(6):2353-9.
2008: Margaret A Park; Guo Zhang; Clint Mitchell; Mohamed Rahmani; Hossein Hamed; Michael P Hagan; Adly Yacoub; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
Molecular cancer therapeutics 2008;7(9):2633-48.
2008: Guo Zhang; Margaret A Park; Clint Mitchell; Hossein Hamed; Mohamed Rahmani; Aditi Pandya Martin; David T Curiel; Adly Yacoub; Martin Graf; Ray Lee; John D Roberts; Paul B Fisher; Steven Grant; Paul Dent
Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(17):5385-99.
2008: Paul Dent; Adly Yacoub; Margaret Park; Devanand Sarkar; Khalid Shah; David T Curiel; Steven Grant; Paul B Fisher
Searching for a cure: gene therapy for glioblastoma.
Cancer biology & therapy 2008;7(9):1335-40.
2008: Essam-Eldin R Othman; Zeng B Zhu; David T Curiel; Nilufar Khatoon; Hosam T Salem; Essam Al-Din M Khalifa; Ayman Al-Hendy
Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells.
American journal of obstetrics and gynecology 2008;199(2):117.e1-6.
2008: Yizhe Tang; Long P Le; Qiana L Matthews; Tie Han; Hongju Wu; David T Curiel
Derivation of a triple mosaic adenovirus based on modification of the minor capsid protein IX.
Virology 2008;377(2):391-400.
2008: Jian Chen; John Wang; Jun Li; Qi Wu; Fei Chu Lim; Pingar Yang; Hui-Chen Hsu; David T Curiel; John D Mountz
Enhancement of cytotoxic T-lymphocyte response in aged mice by a novel treatment with recombinant AdIL-12 and wild-type adenovirus in rapid succession.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1500-6.
2008: Shinichi Sekine; Kosuke Kataoka; Yoshiko Fukuyama; Yasuo Adachi; Julia Davydova; Masato Yamamoto; Ryoki Kobayashi; Kohtaro Fujihashi; Hideaki Suzuki; David T Curiel; Satoshi Shizukuishi; Jerry R McGhee; Kohtaro Fujihashi
A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8126-34.
2008: R Curtis Bird; Patricia DeInnocentes; Steven Lenz; Erin E Thacker; David T Curiel; Bruce F Smith
An allogeneic hybrid-cell fusion vaccine against canine mammary cancer.
Veterinary immunology and immunopathology 2008;123(3-4):289-304.
2008: Yuko Tsuruta; Larisa Pereboeva; Martina Breidenbach; Daniel T Rein; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Paul Dent; Paul B Fisher; David T Curiel
A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3582-8.
2008: Zeng B Zhu; Baogen Lu; Miey Park; Sharmila K Makhija; Thomas M Numnum; James E Kendrick; Minghui Wang; Yuko Tsuruta; Paul Fisher; Ronald D Alvarez; Fen Zhou; Gene P Siegal; Hongju Wu; David T Curiel
Development of an optimized conditionally replicative adenoviral agent for ovarian cancer.
International journal of oncology 2008;32(6):1179-88.
2008: Adly Yacoub; Hossein Hamed; Luni Emdad; Wagner Dos Santos; Pankaj Gupta; William C Broaddus; Viswanathan Ramakrishnan; Devanand Sarkar; Khalid Shah; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors.
Cancer biology & therapy 2008;7(6):917-33.
2008: Pankaj Gupta; Luni Emdad; Irina Lebedeva; Devanand Sarkar; Paul Dent; David T Curiel; Jeffrey Settleman; Paul B Fisher
Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva.
Journal of cellular physiology 2008;215(3):827-36.
2008: C P L Paul; Maaike Everts; Joel N Glasgow; Paul Dent; Paul B Fisher; Ilya V Ulasov; Maciej S. Lesniak; Mariam A Stoff-Khalili; Justin Roth; M A Preuss; C M F Dirven; M L M Lamfers; Gene P Siegal; Zeng B Zhu; David T Curiel
Characterization of infectivity of knob-modified adenoviral vectors in glioma.
Cancer biology & therapy 2008;7(5):786-93.
2008: Justin Roth; David T Curiel; Larisa Pereboeva
Cell vehicle targeting strategies.
Gene therapy 2008;15(10):716-29.
2008: Devanand Sarkar; Zao-Zhong Su; Eun Sook Park; Nicolaq Vozhilla; Paul Dent; David T Curiel; Paul B Fisher
A cancer terminator virus eradicates both primary and distant human melanomas.
Cancer gene therapy 2008;15(5):293-302.
2008: Margaret A Park; Adly Yacoub; Devanand Sarkar; Luni Emdad; Mohamed Rahmani; Sarah Spiegel; Constantinos Koumenis; Martin Graf; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells.
Autophagy 2008;4(4):513-5.
2008: Pedro J Ramírez; Selwyn M Vickers; Hidetaka A Ono; Julia Davydova; Koichi Takayama; Timothy C Thompson; David T Curiel; Kirby I Bland; Masato Yamamoto
Optimization of conditionally replicative adenovirus for pancreatic cancer and its evaluation in an orthotopic murine xenograft model.
American journal of surgery 2008;195(4):481-90.
2008: Margaret A Park; David T Curiel; Constantinos Koumenis; Martin Graf; Ching-Shih Chen; Paul B Fisher; Steven Grant; Paul Dent
PERK-dependent regulation of HSP70 expression and the regulation of autophagy.
Autophagy 2008;4(3):364-7.
2008: Guy Schoehn; Majida El Bakkouri; Céline M S Fabry; Oliver Billet; Leandro Estrozi; Long Le; David T Curiel; Andrey V Kajava; Rob W H Ruigrok; Eric J Kremer
Three-dimensional structure of canine adenovirus serotype 2 capsid.
Journal of virology 2008;82(7):3192-203.
2008: Margaret A Park; Adly Yacoub; Mohamed Rahmani; Guo Zhang; Lori Hart; Michael P Hagan; Stuart K Calderwood; Michael Y Sherman; Constantinos Koumenis; Sarah Spiegel; Ching-Shih Chen; Martin Graf; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells.
Molecular pharmacology 2008;73(4):1168-84.
2008: Mariam A Stoff-Khalili; Angel A Rivera; Ana Nedeljkovic-Kurepa; Arrigo DeBenedetti; Xiao-Lin Li; Yoshinobu Odaka; Jagat Podduturi; Don Arthur Sibley; Gene P Siegal; Alexander Stoff; Scott Young; Zeng B Zhu; David T Curiel; J Michael Mathis
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control.
Breast cancer research and treatment 2008;108(1):43-55.
2008: Adly Yacoub; Pankaj Gupta; Margaret A Park; Mohammed Rhamani; Hossein Hamed; David Hanna; Guo Zhang; Devanand Sarkar; Irina Lebedeva; Luni Emdad; Constantinos Koumenis; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling.
Molecular cancer therapeutics 2008;7(2):314-29.
2008: Adly Yacoub; Margaret A Park; Pankaj Gupta; Mohamed Rahmani; Guo Zhang; Hossein Hamed; David Hanna; Devanand Sarkar; Irina Lebedeva; Luni Emdad; Moira Sauane; Nicollaq Vozhilla; Sarah Spiegel; Constantinos Koumenis; Martin Graf; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.
Molecular cancer therapeutics 2008;7(2):297-313.
2008: Vaibhav Saini; Dmitri Martyshkin; Sergey Mirov; Alex Perez; Guy Perkins; Mark H Ellisman; Victoria D Towner; Hongju Wu; Larisa Pereboeva; Anton Borovjagin; David T Curiel; Maaike Everts
An adenoviral platform for selective self-assembly and targeted delivery of nanoparticles.
Small (Weinheim an der Bergstrasse, Germany) 2008;4(2):262-9.
2008: Junji Uchino; Koichi Takayama; Akiko Harada; T Sone; Taishi Harada; David T Curiel; M Kuroki; Yoichi Nakanishi
Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan.
Cancer gene therapy 2008;15(2):94-100.
2008: D Huang; Alexander Pereboev; N Korokhov; R He; L Larocque; C Gravel; B Jaentschke; M Tocchi; William L Casley; M Lemieux; David T Curiel; W Chen; X Li
Significant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells.
Gene therapy 2008;15(4):298-308.
2008: Qiana L Matthews; Pingar Yang; Qi Wu; Natalya Belousova; Angel A Rivera; Mariam A Stoff-Khalili; Reinhard Waehler; Hui-Chen Hsu; Zan Li; Jing Li; John D Mountz; Hongju Wu; David T Curiel
Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach.
Virology journal 2008;5():98.
2008: Hongju Wu; David T Curiel
Fiber-modified adenoviruses for targeted gene therapy.
Methods in molecular biology (Clifton, N.J.) 2008;434():113-32.
2008: Yosef S Haviv; David T Curiel
Gene therapy for renal cancer.
Contributions to nephrology 2008;159():135-50.
2008: Devanand Sarkar; Paul Dent; David T Curiel; Paul B Fisher
Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: not insurmountable therapeutic problems.
Cancer biology & therapy 2008;7(1):109-12.
2008: Michael J Brumlik; Benjamin J Daniel; Reinhard Waehler; David T Curiel; Francis Giles; Tyler J Curiel
Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy.
Expert opinion on drug delivery 2008;5(1):87-103.
2008: T Michael Numnum; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel Rivera; Mariam A Stoff-Khalili; Ronald D Alvarez; Zeng B Zhu; David T Curiel
Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines.
Gynecologic oncology 2008;108(1):34-41.
2008: Stephan Schierer; Andrea Hesse; Ina Müller; Eckhart Kämpgen; David T Curiel; Gerold Schuler; Alexander Steinkasserer; Dirk M Nettelbeck
Modulation of viability and maturation of human monocyte-derived dendritic cells by oncolytic adenoviruses.
International journal of cancer. Journal international du cancer 2008;122(1):219-29.
2007: Clint Mitchell; Margaret A Park; Guo Zhang; Adly Yacoub; David T Curiel; Paul B Fisher; John D Roberts; Steven Grant; Paul Dent
Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.
Molecular cancer therapeutics 2007;6(12 Pt 1):3101-12.
2007: Luni Emdad; Irina Lebedeva; Zao-Zhong Su; Devanand Sarkar; Paul Dent; David T Curiel; Paul B Fisher
Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells.
Molecular cancer therapeutics 2007;6(11):2985-94.
2007: Zeng B Zhu; J Michael Mathis; Sharmila K Makhija; Baogen Lu; Minghui Wang; Shaonin Ji; Angel A Rivera; Eben Rosenthal; Gene P Siegal; David T Curiel
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck.
International journal of oncology 2007;31(5):1213-22.
2007: Paul B Fisher; Devanand Sarkar; Irina Lebedeva; Luni Emdad; Pankaj Gupta; Moira Sauane; Zao-Zhong Su; Steven Grant; Paul Dent; David T Curiel; Neil Senzer; John Nemunaitis
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.
Toxicology and applied pharmacology 2007;224(3):300-7.
2007: Mariam A Stoff-Khalili; Angel A Rivera; J Michael Mathis; nirupama banerjee; Amanda S Moon; A Hess; Rodney P Rocconi; T Michael Numnum; Maaike Everts; Louise T Chow; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; Hans Georg Bender; Peter Dall; Alexander Stoff; Larisa Pereboeva; David T Curiel
Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma.
Breast cancer research and treatment 2007;105(2):157-67.
2007: Ilya V Ulasov; Angel A Rivera; Yu Han; David T Curiel; Zeng B Zhu; Lesniak Maciej
Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells.
Journal of neurosurgery 2007;107(3):617-27.
2007: Clint Mitchell; Peyman Kabolizadeh; John Ryan; John D Roberts; Adly Yacoub; David T Curiel; Paul B Fisher; Michael P Hagan; Nicholas Farrell; Steven Grant; Paul Dent
Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Molecular pharmacology 2007;72(3):704-14.
2007: Reinhard Waehler; stephen russell; David T Curiel
Engineering targeted viral vectors for gene therapy.
Nature reviews. Genetics 2007;8(8):573-87.
2007: Ilya V Ulasov; Zeng B Zhu; Matthew A Tyler; Yu Han; Angel A Rivera; Andrey Khramtsov; David T Curiel; Lesniak Maciej
Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma.
Human gene therapy 2007;18(7):589-602.
2007: Winan J van Houdt; Hongju Wu; Joel N Glasgow; Martine L M Lamfers; Clemens M F Dirven; G Yancey Gillespie; David T Curiel; Yosef S Haviv
Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models.
Neuro-oncology 2007;9(3):280-90.
2007: Devanand Sarkar; Irina Lebedeva; Zao-Zhong Su; Eun Sook Park; Lejuan Chatman; Nicolaq Vozhilla; Paul Dent; David T Curiel; Paul B Fisher
Eradication of therapy-resistant human prostate tumors using a cancer terminator virus.
Cancer research 2007;67(11):5434-42.
2007: Hua-Jung Li; Maaike Everts; Larisa Pereboeva; Svetlana Komarova; Anat Idan; David T Curiel; Harvey R Herschman
Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter.
Cancer research 2007;67(11):5354-61.
2007: Devanand Sarkar; Irina Lebedeva; Pankaj Gupta; Luni Emdad; Moira Sauane; Paul Dent; David T Curiel; Paul B Fisher
Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?
Expert opinion on biological therapy 2007;7(5):577-86.
2007: Yuko Tsuruta; Larisa Pereboeva; Joel N Glasgow; Daniel T Rein; Yosuke Kawakami; Ronald D Alvarez; Rodney P Rocconi; Gene P Siegal; Paul Dent; Paul B Fisher; David T Curiel
A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(9):2777-83.
2007: Ann M Reynolds; Wei Xia; Mark D Holmes; Sandra J Hodge; Sergei M Danilov; David T Curiel; Nicholas W Morrell; Paul N Reynolds
Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1182-92.
2007: Alexander Stoff; Angel A Rivera; J Michael Mathis; Steven T Moore; nirupama banerjee; Maaike Everts; Antonio Espinosa-de-los-Monteros; Zdenek Novak; Luis O Vasconez; Thomas R Broker; Dirk F Richter; Dale Feldman; Gene P Siegal; Mariam A Stoff-Khalili; David T Curiel
Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds.
Journal of molecular medicine (Berlin, Germany) 2007;85(5):481-96.
2007: John G Page; Baohong Tian; Karen M Schweikart; Joseph Tomaszewski; Ray Harris; Trevor Broadt; Judith Polley-Nelson; Patricia E Noker; Minghui Wang; Sharmila Makhija; Rose Aurigemma; David T Curiel; Ronald D Alvarez
Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer.
American journal of obstetrics and gynecology 2007;196(4):389.e1-9; discussion 389.e9-10.
2007: Larisa Pereboeva; Svetlana Komarova; Justin Roth; Selvarangan Ponnazhagan; David T Curiel
Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus.
Gene therapy 2007;14(8):627-37.
2007: John T Lam; Akseli Hemminki; Anna Kanerva; K B Lee; Jerry L Blackwell; Renee A Desmond; Gene P Siegal; David T Curiel
A three-dimensional assay for measurement of viral-induced oncolysis.
Cancer gene therapy 2007;14(4):421-30.
2007: Matthieu Perreau; Franck J D Mennechet; Nicolas Serratrice; Joel N Glasgow; David T Curiel; Harald Wodrich; Eric J Kremer
Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy.
Journal of virology 2007;81(7):3272-84.
2007: M Adhiambo Witlox; Martine L M Lamfers; Paul I J M Wuisman; David T Curiel; Gene P Siegal
Evolving gene therapy approaches for osteosarcoma using viral vectors: review.
Bone 2007;40(4):797-812.
2007: Rodney P Rocconi; Zeng B Zhu; Mariam A Stoff-Khalili; Angel A Rivera; Baogen Lu; Minghui Wang; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd).
Gynecologic oncology 2007;105(1):113-21.
2007: Hideyo Ugai; Anton V Borovjagin; Long P Le; Minghui Wang; David T Curiel
Thermostability/infectivity defect caused by deletion of the core protein V gene in human adenovirus type 5 is rescued by thermo-selectable mutations in the core protein X precursor.
Journal of molecular biology 2007;366(4):1142-60.
2007: Kristoffer Valerie; Adly Yacoub; Michael P Hagan; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
Radiation-induced cell signaling: inside-out and outside-in.
Molecular cancer therapeutics 2007;6(3):789-801.
2007: Y Tang; Tie Han; Maaike Everts; Zeng B Zhu; G Yancey Gillespie; David T Curiel; Hongju Wu
Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model.
Gene therapy 2007;14(6):523-32.
2007: Irina Lebedeva; Ilyas Washington; Devanand Sarkar; Jennifer A Clark; Robert L Fine; Paul Dent; David T Curiel; Nicholas J Turro; Paul B Fisher
Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3484-9.
2007: Mariam A Stoff-Khalili; Angel A Rivera; Alexander Stoff; J Michael Mathis; Rodney P Rocconi; Qiana L Matthews; Michael T Numnum; Isabell Herrmann; Peter Dall; Devin E Eckhoff; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; David T Curiel
Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer.
International journal of cancer. Journal international du cancer 2007;120(4):935-41.
2007: Naoko Yoshio-Hoshino; Yasuo Adachi; Chieko Aoki; Alexander Pereboev; David T Curiel; Norihiro Nishimoto
Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor.
Cancer research 2007;67(3):871-5.
2007: Zeng B Zhu; Angel A Rivera; Sharmila K Makhija; Baogen Lu; Minghui Wang; Miiru Izumi; Robert James Cerfolio; Mariam A Stoff-Khalili; Fen Zhou; Koichi Takayama; Gene P Siegal; David T Curiel
Targeting lung cancer using an infectivity enhanced CXCR4-CRAd.
Lung cancer (Amsterdam, Netherlands) 2007;55(2):145-56.
2007: Meredith A Preuss; David T Curiel
Gene therapy: science fiction or reality?
Southern medical journal 2007;100(1):101-4.
2007: Qiana L Matthews; David T Curiel
Gene therapy: human germline genetic modifications--assessing the scientific, socioethical, and religious issues.
Southern medical journal 2007;100(1):98-100.
2007: Adly Yacoub; William Hawkins; David Hanna; Hong Young; Margaret A Park; Mark Grant; John D Roberts; David T Curiel; Paul B Fisher; Kristoffer Valerie; Steven Grant; Michael P Hagan; Paul Dent
Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment.
Molecular pharmacology 2007;71(1):259-75.
2007: K Takayama; Paul N Reynolds; Y Adachi; Lyudmila N Kaliberova; J Uchino; Y Nakanishi; David T Curiel
Vascular endothelial growth factor promoter-based conditionally replicative adenoviruses for pan-carcinoma application.
Cancer gene therapy 2007;14(1):105-16.
2006: Bruce F Smith; David T Curiel; Vladimir V Ternovoi; Anton V Borovjagin; Henry J Baker; Nancy Cox; Gene P Siegal
Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs.
Cancer biotherapy & radiopharmaceuticals 2006;21(6):601-6.
2006: Joshua J Short; Chenthamarakshan Vasu; Mark J Holterman; David T Curiel; Alexander Pereboev
Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors.
Virus research 2006;122(1-2):144-53.
2006: Rodney P Rocconi; Michael T Numnum; Zeng B Zhu; Baogen Lu; Minghui Wang; Angel A Rivera; Mariam A Stoff-Khalili; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy.
Gynecologic oncology 2006;103(3):985-9.
2006: Md Ruhul Abid; Shu-Ching Shih; Hasan H Otu; Katherine C Spokes; Yoshiaki Okada; David T Curiel; Takashi Minami; William C Aird
A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression.
The Journal of biological chemistry 2006;281(46):35544-53.
2006: Zeng B Zhu; Yabing Chen; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Masato Yamamoto; shuyi wang; Gene P Siegal; David T Curiel; Jay M McDonald
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.
International journal of oncology 2006;29(5):1319-29.
2006: Natalya Belousova; Raymond Harris; Kurt R Zinn; Mary Ann Rhodes-Selser; Alexander Kotov; Olga Kotova; Minghui Wang; Rosemarie Aurigemma; Zeng B Zhu; David T Curiel; Ronald D Alvarez
Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette.
Molecular pharmacology 2006;70(5):1488-93.
2006: Susan J Hedley; Jian Chen; John D Mountz; Jing Li; David T Curiel; Nikolay Korokhov; Imre Kovesdi
Targeted and shielded adenovectors for cancer therapy.
Cancer immunology, immunotherapy : CII 2006;55(11):1412-9.
2006: Qiana L Matthews; Don Arthur Sibley; Hongju Wu; Jing Li; Mariam A Stoff-Khalili; Reinhard Waehler; J Michael Mathis; David T Curiel
Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion.
Molecular imaging 2006;5(4):510-9.
2006: Tanja Hakkarainen; Akseli Hemminki; David T Curiel; Jarmo Wahlfors
A conditionally replicative adenovirus that codes for a TK-GFP fusion protein (Ad5Delta24TK-GFP) for evaluation of the potency of oncolytic virotherapy combined with molecular chemotherapy.
International journal of molecular medicine 2006;18(4):751-9.
2006: Adly Yacoub; Donna Gilfor; William Hawkins; Margaret A Park; David Hanna; Michael P Hagan; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo.
Cancer biology & therapy 2006;5(10):1332-9.
2006: Yasuo Adachi; Chieko Aoki; Naoko Yoshio-Hoshino; Koichi Takayama; David T Curiel; Norihiro Nishimoto
Interleukin-6 induces both cell growth and VEGF production in malignant mesotheliomas.
International journal of cancer. Journal international du cancer 2006;119(6):1303-11.
2006: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; shuyi wang; Koichi Takayama; Gene P Siegal; Paul N Reynolds; David T Curiel
Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(7):701-11.
2006: Alexander Stoff; Angel A Rivera; nirupama banerjee; J Michael Mathis; Antonio Espinosa-de-los-Monteros; Long P Le; Jorge I de la Torre; Luis O Vasconez; Thomas R Broker; Dirk F Richter; Mariam A Stoff-Khalili; David T Curiel
Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(5):608-17.
2006: Matthew A Tyler; Ilya V Ulasov; Anton Borovjagin; Adam M Sonabend; Andrey Khramtsov; Yu Han; Paul Dent; Paul B Fisher; David T Curiel; Lesniak Maciej
Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus.
Molecular cancer therapeutics 2006;5(9):2408-16.
2006: Pankaj Gupta; Zao-Zhong Su; Irina Lebedeva; Devanand Sarkar; Moira Sauane; Luni Emdad; Michael A Bachelor; Steven Grant; David T Curiel; Paul Dent; Paul B Fisher
mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine.
Pharmacology & therapeutics 2006;111(3):596-628.
2006: Joel N Glasgow; Maaike Everts; David T Curiel
Transductional targeting of adenovirus vectors for gene therapy.
Cancer gene therapy 2006;13(9):830-44.
2006: Martina Breidenbach; Daniel T Rein; Thomas Schöndorf; Kiran N Khan; Isabell Herrmann; Torsten Schmidt; Paul N Reynolds; Israel Vlodavsky; Yosef S Haviv; David T Curiel
A new targeting approach for breast cancer gene therapy using the heparanase promoter.
Cancer letters 2006;240(1):114-22.
2006: Vladimir V Ternovoi; David T Curiel; Bruce F Smith; Gene P Siegal
Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.
Laboratory investigation; a journal of technical methods and pathology 2006;86(8):748-66.
2006: Long P Le; Helen N Le; Amy R Nelson; David A Matthews; Masato Yamamoto; David T Curiel
Core labeling of adenovirus with EGFP.
Virology 2006;351(2):291-302.
2006: Luni Emdad; Devanand Sarkar; Irina Lebedeva; Zao-Zhong Su; Pankaj Gupta; Parameshwar J Mahasreshti; Paul Dent; David T Curiel; Paul B Fisher
Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.
Journal of cellular physiology 2006;208(2):298-306.
2006: Gerd J Bauerschmitz; Kilian Guse; Anna Kanerva; Artur Menzel; Isabell Herrmann; Renee A Desmond; Masato Yamamoto; Dirk M Nettelbeck; Tanja Hakkarainen; Peter Dall; David T Curiel; Akseli Hemminki
Triple-targeted oncolytic adenoviruses featuring the cox2 promoter, E1A transcomplementation, and serotype chimerism for enhanced selectivity for ovarian cancer cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(2):164-74.
2006: Mariam A Stoff-Khalili; Peter Dall; David T Curiel
Gene therapy for carcinoma of the breast.
Cancer gene therapy 2006;13(7):633-47.
2006: Masaharu Nakayama; Gerald W Both; Boglarka Banizs; Yuko Tsuruta; Seiji Yamamoto; Yosuke Kawakami; Joanne T Douglas; Kenzaburo Tani; David T Curiel; Joel N Glasgow
An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice.
Virology 2006;350(1):103-15.
2006: Jian Chen; Hui-Chen Hsu; Allan J Zajac; Qi Wu; Pingar Yang; Xin Xu; Sylvia A McPherson; Jun Li; David T Curiel; John D Mountz
In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin.
Human gene therapy 2006;17(6):669-82.
2006: Mariam A Stoff-Khalili; Angel A Rivera; Long P Le; Alexander Stoff; Maaike Everts; Juan L Contreras; D Chen; L Teng; Marianne G Rots; Hidde J Haisma; Rodney P Rocconi; Gerd J Bauerschmitz; Daniel T Rein; Masato Yamamoto; Gene P Siegal; Peter Dall; J Michael Mathis; David T Curiel
Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents.
Cancer gene therapy 2006;13(6):606-18.
2006: Lotta Kangasniemi; Tuula Kiviluoto; Anna Kanerva; Mari Raki; Tuuli Ranki; Merja Sarkioja; Hongju Wu; Frank Marini; Krister Höckerstedt; Helena Isoniemi; Henrik Alfthan; Ulf-Hakan Stenman; David T Curiel; Akseli Hemminki
Infectivity-enhanced adenoviruses deliver efficacy in clinical samples and orthotopic models of disseminated gastric cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(10):3137-44.
2006: J Michael Mathis; Phoebe L Stewart; Zeng B Zhu; David T Curiel
Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(9):2651-6.
2006: Winan J van Houdt; Yosef S Haviv; Baogen Lu; Minghui Wang; Angel A Rivera; Ilya V Ulasov; Martine L M Lamfers; Daniel T Rein; Lesniak Maciej; Gene P Siegal; Clemens M F Dirven; David T Curiel; Zeng B Zhu
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
Journal of neurosurgery 2006;104(4):583-92.
2006: Maaike Everts; Vaibhav Saini; Jennifer L Leddon; Robbert J Kok; Mariam A Stoff-Khalili; Meredith A Preuss; C Leigh Millican; Guy Perkins; Joshua M Brown; Hitesh G Bagaria; David E Nikles; Duane T Johnson; Vladimir P Zharov; David T Curiel
Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy.
Nano letters 2006;6(4):587-91.
2006: Svetlana Komarova; Yosuke Kawakami; Mariam A Stoff-Khalili; David T Curiel; Larisa Pereboeva
Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses.
Molecular cancer therapeutics 2006;5(3):755-66.
2006: Sam C Noureddini; Alexander Krendelshchikov; Vera Simonenko; Susan J Hedley; Joanne T Douglas; David T Curiel; Nikolay Korokhov
Generation and selection of targeted adenoviruses embodying optimized vector properties.
Virus research 2006;116(1-2):185-95.
2006: Long P Le; Angel A Rivera; Joel N Glasgow; Vladimir V Ternovoi; Hongju Wu; Minghui Wang; Bruce F Smith; Gene P Siegal; David T Curiel
Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells.
Gene therapy 2006;13(5):389-99.
2006: Parameshwar J Mahasreshti; Manjula Kataram; Hongju Wu; Laxmi Priya Yalavarthy; Delicia Carey; Paul B Fisher; Sunil Chada; Ronald D Alvarez; Hidde J Haisma; Paul Dent; David T Curiel
Ovarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy.
Gynecologic oncology 2006;100(3):521-32.
2006: Daniel T Rein; Martina Breidenbach; David T Curiel
Current developments in adenovirus-based cancer gene therapy.
Future oncology (London, England) 2006;2(1):137-43.
2006: David T Curiel; Zeng B Zhu
Combining chemotherapy with virotherapy: a novel treatment strategy for malignant pleural mesothelioma.
Cancer biology & therapy 2006;5(2):236-7.
2006: Long P Le; Helen N Le; Igor Dmitriev; Julia Davydova; Tatyana Gavrikova; Seiji Yamamoto; David T Curiel; Masato Yamamoto
Dynamic monitoring of oncolytic adenovirus in vivo by genetic capsid labeling.
Journal of the National Cancer Institute 2006;98(3):203-14.
2006: Masato Yamamoto; N Nishimoto; Julia Davydova; T Kishimoto; David T Curiel
Suppressor of cytokine signaling-1 expression by infectivity-enhanced adenoviral vector inhibits IL-6-dependent proliferation of multiple myeloma cells.
Cancer gene therapy 2006;13(2):194-202.
2006: Candelaria Gomez-Manzano; Marta M Alonso; W K Alfred Yung; Frank McCormick; David T Curiel; Frederick F Lang; Hong Jiang; B Nebiyou Bekele; Xian Zhou; Ramon Alemany; Juan Fueyo
Delta-24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):556-62.
2006: Choon-Taek Lee; Yoon-Jin Lee; Sung-Youn Kwon; Jaeho Lee; Kwang Il Kim; Kyung-Ho Park; Joo Hyun Kang; Chul-Gyu Yoo; Young Whan Kim; Sung Koo Han; June-Key Chung; Young-Soo Shim; David T Curiel; David P Carbone
In vivo imaging of adenovirus transduction and enhanced therapeutic efficacy of combination therapy with conditionally replicating adenovirus and adenovirus-p27.
Cancer research 2006;66(1):372-7.
2006: Susan J Hedley; Adrian Auf der Maur; S Hohn; Dominik Escher; Alcide Barberis; Joel N Glasgow; Joanne T Douglas; Nikolay Korokhov; David T Curiel
An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery.
Gene therapy 2006;13(1):88-94.
2005: Vladimir P Zharov; Jin-Woo Kim; David T Curiel; Maaike Everts
Self-assembling nanoclusters in living systems: application for integrated photothermal nanodiagnostics and nanotherapy.
Nanomedicine : nanotechnology, biology, and medicine 2005;1(4):326-45.
2005: Rodney P Rocconi; T Michael Numnum; Mariam A Stoff-Khalili; Sharmila K Makhija; Ronald D Alvarez; David T Curiel
Targeted gene therapy for ovarian cancer.
Current gene therapy 2005;5(6):643-53.
2005: Long P Le; Jing Li; Vladimir V Ternovoi; Gene P Siegal; David T Curiel
Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein.
The Journal of general virology 2005;86(Pt 12):3201-8.
2005: Miiru Izumi; Yosuke Kawakami; Joel N Glasgow; Natalya Belousova; Maaike Everts; SangAe Kim-Park; Seiji Yamamoto; Minghui Wang; Long P Le; Paul N Reynolds; David T Curiel
In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model.
The journal of gene medicine 2005;7(12):1517-25.
2005: Mariam A Stoff-Khalili; Angel A Rivera; Joel N Glasgow; Long P Le; Alexander Stoff; Maaike Everts; Yuko Tsuruta; Yosuke Kawakami; Gerd J Bauerschmitz; J Michael Mathis; Larisa Pereboeva; G P Seigal; Peter Dall; David T Curiel
A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy.
Gene therapy 2005;12(23):1696-706.
2005: J Michael Mathis; Mariam A Stoff-Khalili; David T Curiel
Oncolytic adenoviruses - selective retargeting to tumor cells.
Oncogene 2005;24(52):7775-91.
2005: Michael J Passineau; Gene P Siegal; Maaike Everts; Alexander Pereboev; Darshana Jhala; Minghui Wang; Zeng B Zhu; Sangae Kim Park; David T Curiel; Gina M Nelson
The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma.
Leukemia & lymphoma 2005;46(11):1627-1638.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; J Michael Mathis; Maaike Everts; Minghui Wang; Yosuke Kawakami; Reinhard Waehler; Quiana L Mathews; Masato Yamamoto; Rodney P Rocconi; Gene P Siegal; Dirk F Richter; Peter Dall; Zeng B Zhu; David T Curiel
Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.
Cancer biology & therapy 2005;4(11):1203-10.
2005: Yuko Tsuruta; Larisa Pereboeva; Joel N Glasgow; Cindy L Luongo; Svetlana Komarova; Yosuke Kawakami; David T Curiel
Reovirus sigma1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway.
Biochemical and biophysical research communications 2005;335(1):205-14.
2005: Sam C Noureddini; David T Curiel
Genetic targeting strategies for adenovirus.
Molecular pharmaceutics 2005;2(5):341-7.
2005: Junji Uchino; Koichi Takayama; Akiko Harada; Yosuke Kawakami; Hiroyuki Inoue; David T Curiel; Yoichi Nakanishi
Infectivity enhanced, hTERT promoter-based conditionally replicative adenoviruses are useful for SCLC treatment.
Cancer gene therapy 2005;12(9):737-48.
2005: Masato Yamamoto; David T Curiel
Cancer gene therapy.
Technology in cancer research & treatment 2005;4(4):315-30.
2005: Jing Li; Long P Le; Don Arthur Sibley; J Michael Mathis; David T Curiel
Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion.
Virology 2005;338(2):247-58.
2005: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; SangAe Kim-Park; Ilya V Ulasov; Fen Zhou; Ronald D Alvarez; Gene P Siegal; David T Curiel
Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo.
International journal of oncology 2005;27(1):237-46.
2005: Paul Dent; Adly Yacoub; Steven Grant; David T Curiel; Paul B Fisher
MDA-7/IL-24 regulates proliferation, invasion and tumor cell radiosensitivity: a new cancer therapy?
Journal of cellular biochemistry 2005;95(4):712-9.
2005: J Chen; Allan J Zajac; S A McPherson; Hui-Chen Hsu; P Yang; Qi Wu; Xin Xu; X Wang; K Fujihashi; David T Curiel; John D Mountz
Primary adenovirus-specific cytotoxic T lymphocyte response occurs after viral clearance and liver enzyme elevation.
Gene therapy 2005;12(13):1079-88.
2005: Maaike Everts; SangAe Kim-Park; Meredith A Preuss; Michael J Passineau; Joel N Glasgow; Alexander Pereboev; Parameshwar J Mahasreshti; William E Grizzle; Paul N Reynolds; David T Curiel
Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors.
Gene therapy 2005;12(13):1042-8.
2005: Mami Hosokawa; Ritsuko Kadota; Shigeki Shichijo; Kyogo Itoh; Igor Dmitriev; Victor Krasnykh; David T Curiel; Yoichi Takue; Hiro Wakasugi; Shigemitsu Takashima; Yuji Heike
Cell cycle arrest and apoptosis induced by SART-1 gene transduction.
Anticancer research 2005;25(3B):1983-90.
2005: Nikolay Korokhov; Sam C Noureddini; David T Curiel; Saskia J A M Santegoets; Rik J Scheper; Tanja D de Gruijl
A single-component CD40-targeted adenovirus vector displays highly efficient transduction and activation of dendritic cells in a human skin substrate system.
Molecular pharmaceutics 2005;2(3):218-23.
2005: Yaman Tekant; Julia Davydova; Pedro J Ramirez; David T Curiel; Selwyn M Vickers; Masato Yamamoto
Oncolytic adenoviral therapy in gallbladder carcinoma.
Surgery 2005;137(5):527-35.
2005: Anton V Borovjagin; Alexandre Krendelchtchikov; Nagarajan Ramesh; De-Chao Yu; Joanne T Douglas; David T Curiel
Complex mosaicism is a novel approach to infectivity enhancement of adenovirus type 5-based vectors.
Cancer gene therapy 2005;12(5):475-86.
2005: Birgit Ø Engesaeter; Anette Bonsted; Kristian Berg; Anders Høgset; Olav Engebråten; Øystein Fodstad; David T Curiel; Gunhild M Maelandsmo
PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles.
Cancer gene therapy 2005;12(5):439-48.
2005: Nikolay Korokhov; Tanja D de Gruijl; Wayne A Aldrich; Pierre L Triozzi; Papia T Banerjee; Stephen D Gillies; Tyler J Curiel; Joanne T Douglas; Rik J Scheper; David T Curiel
High efficiency transduction of dendritic cells by adenoviral vectors targeted to DC-SIGN.
Cancer biology & therapy 2005;4(3):289-94.
2005: Hongju Wu; Tie Han; Natalya Belousova; Victor Krasnykh; Elena Kashentseva; Igor Dmitriev; Manjula Kataram; Parameshwar J Mahasreshti; David T Curiel
Identification of sites in adenovirus hexon for foreign peptide incorporation.
Journal of virology 2005;79(6):3382-90.
2005: Daniel T Rein; Martina Breidenbach; Tyler O Kirby; Tie Han; Gene P Siegal; Gerd J Bauerschmitz; Minghui Wang; Dirk M Nettelbeck; Yuko Tsuruta; Masato Yamamoto; Peter Dall; Akseli Hemminki; David T Curiel
A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(3):1327-35.
2005: Baogen Lu; Sharmila K Makhija; Dirk M Nettelbeck; Angel A Rivera; Minghui Wang; Svetlana Komarova; Fen Zhou; Masato Yamamoto; Hidde J Haisma; Ronald D Alvarez; David T Curiel; Zeng B Zhu
Evaluation of tumor-specific promoter activities in melanoma.
Gene therapy 2005;12(4):330-8.
2005: Minghui Wang; Akseli Hemminki; Gene P Siegal; Mack N Barnes; Igor Dmitriev; Victor Krasnykh; Bin Liu; David T Curiel; Ronald D Alvarez
Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.
Gynecologic oncology 2005;96(2):341-8.
2005: Andrea L Volk; Angel A Rivera; Grier P Page; Jesus F Salazar-Gonzalez; Dirk M Nettelbeck; Qiana L Matthews; David T Curiel
Employment of microarray analysis to characterize biologic differences associated with tropism-modified adenoviral vectors: utilization of non-native cellular entry pathways.
Cancer gene therapy 2005;12(2):162-74.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; nirupama banerjee; Maaike Everts; Scott Young; Gene P Siegal; Dirk F Richter; Minghui Wang; Peter Dall; J Michael Mathis; Zeng B Zhu; David T Curiel
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system.
Breast cancer research : BCR 2005;7(6):R1141-52.
2005: Irina V Balyasnikova; Roman Metzger; David J Visintine; Vidas Dimasius; Zhu-Li Sun; Yuliya V Berestetskaya; Timothy B. McDonald; David T Curiel; Richard D Minshall; Sergei M Danilov
Selective rat lung endothelial targeting with a new set of monoclonal antibodies to angiotensin I-converting enzyme.
Pulmonary pharmacology & therapeutics 2005;18(4):251-67.
2005: Hidetaka A Ono; Julia Davydova; Yasuo Adachi; Koichi Takayama; Shannon D Barker; Paul N Reynolds; Victor Krasnykh; Chikara Kunisaki; Hiroshi Shimada; David T Curiel; Masato Yamamoto
Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer.
Journal of gastroenterology 2005;40(1):31-42.
2005: jacques grill; Martine L M Lamfers; Victor W van Beusechem; Paul Van Der Valk; Anne Huisman; Peter Sminia; Ramon Alemany; David T Curiel; W Peter Vandertop; Winald Gerritsen; Clemens M F Dirven
Oncolytic virotherapy of meningiomas in vitro with replication-competent adenovirus.
Neurosurgery 2005;56(1):146-53; discussion 153-4.
2005: Vladimir V Ternovoi; Long P Le; Natalya Belousova; Bruce F Smith; Gene P Siegal; David T Curiel
Productive replication of human adenovirus type 5 in canine cells.
Journal of virology 2005;79(2):1308-11.
2005: Martina Breidenbach; Daniel T Rein; Maaike Everts; Joel N Glasgow; Minghui Wang; Michael J Passineau; Ronald D Alvarez; Nikolay Korokhov; David T Curiel
Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy.
Gene therapy 2005;12(2):187-93.
2005: Anna Kanerva; Kurt R Zinn; K-W Peng; Tuuli Ranki; Lotta Kangasniemi; T R Chaudhuri; Renee A Desmond; M Wang; K Takayama; Tanja Hakkarainen; Henrik Alfthan; Ulf-Hakan Stenman; David T Curiel; Akseli Hemminki
Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus.
Gene therapy 2005;12(1):87-94.
2005: Gandham Mahendra; Sanjay Kumar; Tatyana Isayeva; Parameshwar J Mahasreshti; David T Curiel; Cecil R Stockardt; William E Grizzle; Vidya Alapati; Raj K Singh; Gene P Siegal; Sreelatha Meleth; Selvarangan Ponnazhagan
Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor.
Cancer gene therapy 2005;12(1):26-34.
2004: Tyler O Kirby; Angel Rivera; Daniel T Rein; Minghui Wang; Ilya V Ulasov; Martina Breidenbach; Manjula Kataram; Juan L Contreras; Carlos Krumdieck; Masato Yamamoto; Marianne G Rots; Hidde J Haisma; Ronald D Alvarez; Parameshwar J Mahasreshti; David T Curiel
A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8697-703.
2004: Mariam A Stoff-Khalili; Peter Dall; David T Curiel
From gene therapy to virotherapy for ovarian cancer.
Minerva ginecologica 2004;56(6):503-14.
2004: Angel A Rivera; Julia Davydova; S Schierer; Minghui Wang; Victor Krasnykh; Masato Yamamoto; David T Curiel; Dirk M Nettelbeck
Combining high selectivity of replication with fiber chimerism for effective adenoviral oncolysis of CAR-negative melanoma cells.
Gene therapy 2004;11(23):1694-702.
2004: John T Lam; Anna Kanerva; Gerd J Bauerschmitz; Koichi Takayama; Kaori Suzuki; Masato Yamamoto; Snehal M Bhoola; Bin Liu; Minghui Wang; Mack N Barnes; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
Inter-patient variation in efficacy of five oncolytic adenovirus candidates for ovarian cancer therapy.
The journal of gene medicine 2004;6(12):1333-42.
2004: Qianwa Liang; Masato Yamamoto; David T Curiel; Harvey R Herschman
Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(6):395-404.
2004: Qianwa Liang; Igor Dmitriev; Elena Kashentseva; David T Curiel; Harvey R Herschman
Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(6):385-94.
2004: Daniel T Rein; Martina Breidenbach; Dirk M Nettelbeck; Yosuke Kawakami; Gene P Siegal; Warner K Huh; Minghui Wang; Akseli Hemminki; Gerd J Bauerschmitz; Masato Yamamoto; Yasuo Adachi; Koichi Takayama; Peter Dall; David T Curiel
Evaluation of tissue-specific promoters in carcinomas of the cervix uteri.
The journal of gene medicine 2004;6(11):1281-9.
2004: Daniel T Rein; Martina Breidenbach; Hongju Wu; Tie Han; Yosef S Haviv; Minghui Wang; Tyler O Kirby; Yosuke Kawakami; Peter Dall; Ronald D Alvarez; David T Curiel
Gene transfer to cervical cancer with fiber-modified adenoviruses.
International journal of cancer. Journal international du cancer 2004;111(5):698-704.
2004: Choon-Taek Lee; Kyung-Ho Park; Kiyoshi Yanagisawa; Yasushi Adachi; Joyce E Ohm; Sorena Nadaf; Mikhail M Dikov; David T Curiel; David P Carbone
Combination therapy with conditionally replicating adenovirus and replication defective adenovirus.
Cancer research 2004;64(18):6660-5.
2004: Larisa Pereboeva; Svetlana Komarova; Parameshwar J Mahasreshti; David T Curiel
Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors.
Virus research 2004;105(1):35-46.
2004: Maaike Everts; David T Curiel
Transductional targeting of adenoviral cancer gene therapy.
Current gene therapy 2004;4(3):337-46.
2004: Juan L Contreras; Dong Xie; Jimmy Mays; Cheryl A Smyth; Christopher Eckstein; Firoz G Rahemtulla; Carlton J Young; J Anthony Thompson; Guadalupe Bilbao; David T Curiel; Devin E Eckhoff
A novel approach to xenotransplantation combining surface engineering and genetic modification of isolated adult porcine islets.
Surgery 2004;136(3):537-47.
2004: Gerd J Bauerschmitz; Anna Kanerva; Minghui Wang; Isabell Herrmann; Denise R Shaw; Theresa V Strong; Renee A Desmond; Daniel T Rein; Peter Dall; David T Curiel; Akseli Hemminki
Evaluation of a selectively oncolytic adenovirus for local and systemic treatment of cervical cancer.
International journal of cancer. Journal international du cancer 2004;111(2):303-9.
2004: Charles A Leath; Manjula Kataram; Pradeep Bhagavatula; Rahul V Gopalkrishnan; Paul Dent; Paul B Fisher; Alexander Pereboev; Delicia Carey; Irina Lebedeva; Hidde J Haisma; Ronald D Alvarez; David T Curiel; Parameshwar J Mahasreshti
Infectivity enhanced adenoviral-mediated mda-7/IL-24 gene therapy for ovarian carcinoma.
Gynecologic oncology 2004;94(2):352-62.
2004: Adly Yacoub; Clint Mitchell; Young Hong; Rahul V Gopalkrishnan; Zao-Zhong Su; Pankaj Gupta; Moria Sauane; Irina Lebedeva; David T Curiel; Parameshwar J Mahasreshti; Myrna R Rosenfeld; William C Broaddus; C David James; Steven Grant; Paul B Fisher; Paul Dent
MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
Cancer biology & therapy 2004;3(8):739-51.
2004: Miriam Ferrer; Johan P de Winter; D C Jeroen Mastenbroek; David T Curiel; Winald Gerritsen; Giuseppe Giaccone; Frank A E Kruyt
Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA.
Cancer gene therapy 2004;11(8):539-46.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Meredith Preuss; Fen Zhou; Gene P Siegal; Ronald D Alvarez; David T Curiel
Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.
Virology 2004;325(1):116-28.
2004: Joel N Glasgow; Eric J Kremer; Akseli Hemminki; Gene P Siegal; Joanne T Douglas; David T Curiel
An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism.
Virology 2004;324(1):103-16.
2004: Yosef S Haviv; Winan J van Houdt; Baogen Lu; David T Curiel; Zeng B Zhu
Transcriptional targeting in renal cancer cell lines via the human CXCR4 promoter.
Molecular cancer therapeutics 2004;3(6):687-91.
2004: Martina Breidenbach; Daniel T Rein; Minghui Wang; Dirk M Nettelbeck; Akseli Hemminki; Ilya V Ulasov; Angel R Rivera; Maaike Everts; Ronald D Alvarez; Joanne T Douglas; David T Curiel
Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy.
Human gene therapy 2004;15(5):509-18.
2004: Meredith A Preuss; John T Lam; Minghui Wang; Charles A Leath; Manjula Kataram; Parameshwar J Mahasreshti; Ronald D Alvarez; David T Curiel
Transcriptional blocks limit adenoviral replication in primary ovarian tumor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3189-94.
2004: Alexander Pereboev; Jill M Nagle; Mikhail A Shakhmatov; Pierre L Triozzi; Qiana L Matthews; Yosuke Kawakami; David T Curiel; Jerry L Blackwell
Enhanced gene transfer to mouse dendritic cells using adenoviral vectors coated with a novel adapter molecule.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(5):712-20.
2004: Joshua J Short; Alexander Pereboev; Yosuke Kawakami; Chenthamarakshan Vasu; Mark J Holterman; David T Curiel
Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors.
Virology 2004;322(2):349-59.
2004: Hongju Wu; Tie Han; John T Lam; Charles A Leath; Igor Dmitriev; Elena Kashentseva; Mack N Barnes; Ronald D Alvarez; David T Curiel
Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy.
Gene therapy 2004;11(10):874-8.
2004: Long P Le; Maaike Everts; Igor Dmitriev; Julia Davydova; Masato Yamamoto; David T Curiel
Fluorescently labeled adenovirus with pIX-EGFP for vector detection.
Molecular imaging 2004;3(2):105-16.
2004: nirupama banerjee; Angel A Rivera; Minghui Wang; Louise T Chow; Thomas R Broker; David T Curiel; Dirk M Nettelbeck
Analyses of melanoma-targeted oncolytic adenoviruses with tyrosinase enhancer/promoter-driven E1A, E4, or both in submerged cells and organotypic cultures.
Molecular cancer therapeutics 2004;3(4):437-49.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Masato Yamamoto; M Yamaoto; Ronald D Alvarez; David T Curiel
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Gene therapy 2004;11(7):645-8.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Shannon Barker; Masato Yamaoto; Fengzhi Li; Ronald D Alvarez; David T Curiel
Transcriptional targeting of tumors with a novel tumor-specific survivin promoter.
Cancer gene therapy 2004;11(4):256-62.
2004: Charles A Leath; Joanne T Douglas; David T Curiel; Ronald D Alvarez
Single-chain antibodies: A therapeutic modality for cancer gene therapy (review).
International journal of oncology 2004;24(4):765-71.
2004: Joel N Glasgow; Gerd J Bauerschmitz; David T Curiel; Akseli Hemminki
Transductional and transcriptional targeting of adenovirus for clinical applications.
Current gene therapy 2004;4(1):1-14.
2004: Paola Grandi; Samuel Wang; Deborah Schuback; Victor Krasnykh; Matthew Spear; David T Curiel; Roberto Manservigi; Xandra O Breakefield
HSV-1 virions engineered for specific binding to cell surface receptors.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(3):419-27.
2004: Angel A Rivera; Minghui Wang; Kaori Suzuki; taco uil; Victor Krasnykh; David T Curiel; Dirk M Nettelbeck
Mode of transgene expression after fusion to early or late viral genes of a conditionally replicating adenovirus via an optimized internal ribosome entry site in vitro and in vivo.
Virology 2004;320(1):121-34.
2004: Anna Kanerva; Gerd J Bauerschmitz; Masato Yamamoto; John T Lam; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
A cyclooxygenase-2 promoter-based conditionally replicating adenovirus with enhanced infectivity for treatment of ovarian adenocarcinoma.
Gene therapy 2004;11(6):552-9.
2004: James A. Bonner; Donald J Buchsbaum; Buck E Rogers; William E Grizzle; Hoa Q Trummell; David T Curiel; John B Fiveash; Roger Ove; Kevin P Raisch
Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells.
International journal of radiation oncology, biology, physics 2004;58(3):950-8.
2004: Suzanne M Verwijnen; Peter A E Sillevis Smith; Rob Hoeben; Martin J W E Rabelink; Leonard Wiebe; David T Curiel; Akseli Hemminki; Eric P Krenning; Marion De Jong
Molecular imaging and treatment of malignant gliomas following adenoviral transfer of the herpes simplex virus-thymidine kinase gene and the somatostatin receptor subtype 2 gene.
Cancer biotherapy & radiopharmaceuticals 2004;19(1):111-20.
2004: Larisa Pereboeva; David T Curiel
Cellular vehicles for cancer gene therapy: current status and future potential.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2004;18(6):361-85.
2004: Juan L Contreras; Cheryl A Smyth; David T Curiel; Devin E Eckhoff
Nonhuman primate models in type 1 diabetes research.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2004;45(3):334-42.
2004: James A. Bonner; Donald J Buchsbaum; Suzanne M Russo; John B Fiveash; Hoa Q Trummell; David T Curiel; Kevin P Raisch
Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression.
International journal of radiation oncology, biology, physics 2004;59(2 Suppl):2-10.
2004: Laura Timares; Joanne T Douglas; Bryan W Tillman; Victor Krasnykh; David T Curiel
Adenovirus-mediated gene delivery to dendritic cells.
Methods in molecular biology (Clifton, N.J.) 2004;246():139-54.
2004: Adhiambo M Witlox; Victor W van Beusechem; Bonnie Molenaar; Hans Bras; Gerard R Schaap; Ramon Alemany; David T Curiel; HERBERT PINEDO; Paul I J M Wuisman; Winald Gerritsen
Conditionally replicative adenovirus with tropism expanded towards integrins inhibits osteosarcoma tumor growth in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):61-7.
2004: Masato Yamamoto; David T Curiel
Nonreplicating DNA viral vectors for suicide gene therapy: the adenoviral vectors.
Methods in molecular medicine 2004;90():61-70.
2004: Dirk M Nettelbeck; Angel A Rivera; Jörg Kupsch; Detlef Dieckmann; Joanne T Douglas; Roland Kontermann; Ramon Alemany; David T Curiel
Retargeting of adenoviral infection to melanoma: combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA.
International journal of cancer. Journal international du cancer 2004;108(1):136-45.
2003: Nikolay Korokhov; Galina Mikheeva; Alexander Krendelshchikov; Natalya Belousova; Vera Simonenko; Valentina Krendelshchikova; Alexander Pereboev; Alexander Kotov; Olga Kotova; Pierre L Triozzi; Wayne A Aldrich; Joanne T Douglas; Kin-Ming Lo; Papia T Banerjee; Stephen D Gillies; David T Curiel; Victor Krasnykh
Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge.
Journal of virology 2003;77(24):12931-40.
2003: Christianne J Buskens; Willem A Marsman; John G Wesseling; G Johan A Offerhaus; Masato Yamamoto; David T Curiel; Piter J Bosma; J J B van Lanschot
A genetically retargeted adenoviral vector enhances viral transduction in esophageal carcinoma cell lines and primary cultured esophageal resection specimens.
Annals of surgery 2003;238(6):815-24; discussion 825-6.
2003: Natalya Belousova; Nikolay Korokhov; Valentina Krendelshchikova; Vera Simonenko; Galina Mikheeva; Pierre L Triozzi; Wayne A Aldrich; Papia T Banerjee; Stephen D Gillies; David T Curiel; Victor Krasnykh
Genetically targeted adenovirus vector directed to CD40-expressing cells.
Journal of virology 2003;77(21):11367-77.
2003: Anita G M Stam; Saskia J A M Santegoets; Theresia M Westers; Claudia C Sombroek; J J W M Janssen; Bryan W Tillman; Arjan A van de Loosdrecht; HERBERT PINEDO; David T Curiel; Gert Ossenkoppele; Rik J Scheper; Tanja D de Gruijl
CD40-targeted adenoviral GM-CSF gene transfer enhances and prolongs the maturation of human CML-derived dendritic cells upon cytokine deprivation.
British journal of cancer 2003;89(7):1162-5.
2003: Yosef S Haviv; Koichi Takayama; Peter Nagi; Albert Tousson; William Cook; Minghui Wang; John T Lam; Seiji Naito; Xiaosheng Lei; Delicia E Carey; David T Curiel
Modulation of renal glomerular disease using remote delivery of adenoviral-encoded solubletype II TGF-beta receptor fusion molecule.
The journal of gene medicine 2003;5(10):839-51.
2003: Masato Yamamoto; Julia Davydova; Minghui Wang; Gene P Siegal; Victor Krasnykh; Selwyn M Vickers; David T Curiel
Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer.
Gastroenterology 2003;125(4):1203-18.
2003: Dirk M Nettelbeck; David T Curiel
Tumor-busting viruses.
Scientific American 2003;289(4):68-75.
2003: Andrea L Volk; Angel A Rivera; Anna Kanerva; Gerd J Bauerschmitz; Igor Dmitriev; Dirk M Nettelbeck; David T Curiel
Enhanced adenovirus infection of melanoma cells by fiber-modification: incorporation of RGD peptide or Ad5/3 chimerism.
Cancer biology & therapy 2003;2(5):511-5.
2003: Anna Kanerva; Kurt R Zinn; Tandra R Chaudhuri; John T Lam; Kaori Suzuki; taco uil; Tanja Hakkarainen; Gerd J Bauerschmitz; Minghui Wang; Bin Liu; Zhihong Cao; Ronald D Alvarez; David T Curiel; Akseli Hemminki
Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):449-58.
2003: Tyler O Kirby; David T Curiel; Ronald D Alvarez
Gene therapy for ovarian cancer: progress and potential.
Hematology/oncology clinics of North America 2003;17(4):1021-50.
2003: Akseli Hemminki; Minghui Wang; Tanja Hakkarainen; Renee A Desmond; Jarmo Wahlfors; David T Curiel
Production of an EGFR targeting molecule from a conditionally replicating adenovirus impairs its oncolytic potential.
Cancer gene therapy 2003;10(8):583-8.
2003: Yosef S Haviv; David T Curiel
Engineering regulatory elements for conditionally-replicative adeno-viruses.
Current gene therapy 2003;3(4):357-85.
2003: Juan L Contreras; Hongju Wu; Cheryl A Smyth; Christopher Eckstein; Carlton J Young; Toshiro Seki; Guadalupe Bilbao; David T Curiel; Devin E Eckhoff
Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets.
Transplantation 2003;76(1):252-61.
2003: Paul B Fisher; Rahul V Gopalkrishnan; Sunil Chada; Rajagopal Ramesh; Elizabeth A Grimm; Myrna R Rosenfeld; David T Curiel; Paul Dent
mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.
Cancer biology & therapy 2003;2(4 Suppl 1):S23-37.
2003: Parameshwar J Mahasreshti; Manjula Kataram; Ming H Wang; Cecil R Stockard; William E Grizzle; Delicia Carey; Gene P Siegal; Hidde J Haisma; Ronald D Alvarez; David T Curiel
Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2701-10.
2003: Shannon D Barker; Igor Dmitriev; Dirk M Nettelbeck; Bin Liu; Angel A Rivera; Ronald D Alvarez; David T Curiel; Akseli Hemminki
Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma.
Gene therapy 2003;10(14):1198-204.
2003: Juan L Contreras; Cheryl A Smyth; Guadalupe Bilbao; Christopher Eckstein; Carlton J Young; John A Thompson; David T Curiel; Devin E Eckhoff
Coupling endoplasmic reticulum stress to cell death program in isolated human pancreatic islets: effects of gene transfer of Bcl-2.
Transplant international : official journal of the European Society for Organ Transplantation 2003;16(7):537-42.
2003: Joana G Brandão; Rik J Scheper; Sinéad M Lougheed; David T Curiel; Bryan W Tillman; Winald Gerritsen; Alfons J M van den Eertwegh; HERBERT PINEDO; Hidde J Haisma; Tanja D de Gruijl
CD40-targeted adenoviral gene transfer to dendritic cells through the use of a novel bispecific single-chain Fv antibody enhances cytotoxic T cell activation.
Vaccine 2003;21(19-20):2268-72.
2003: Dirk M Nettelbeck; Angel A Rivera; Julia Davydova; D Dieckmann; Masato Yamamoto; David T Curiel
Cyclooxygenase-2 promoter for tumour-specific targeting of adenoviral vectors to melanoma.
Melanoma research 2003;13(3):287-92.
2003: Francisco Noya; Cristina Balagué; nirupama banerjee; David T Curiel; Thomas R Broker; Louise T Chow
Activation of adenovirus early promoters and lytic phase in differentiated strata of organotypic cultures of human keratinocytes.
Journal of virology 2003;77(11):6533-40.
2003: Koichi Takayama; Paul N Reynolds; Joshua J Short; Yosuke Kawakami; Yasuo Adachi; Joel N Glasgow; Marianne G Rots; Victor Krasnykh; Joanne T Douglas; David T Curiel
A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism.
Virology 2003;309(2):282-93.
2003: Juan Fueyo; Ramon Alemany; Candelaria Gomez-Manzano; Gregory N Fuller; Asadullah Khan; Charles A Conrad; Ta-Jen Liu; Hong Jiang; Michael G Lemoine; Kaori Suzuki; Raymond Sawaya; David T Curiel; W K Alfred Yung; Frederick F Lang
Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway.
Journal of the National Cancer Institute 2003;95(9):652-60.
2003: John T Lam; Gerd J Bauerschmitz; Anna Kanerva; Shannon D Barker; J Michael Straughn; Minghui Wang; Mack N Barnes; Jerry L Blackwell; Gene P Siegal; Ronald D Alvarez; David T Curiel; Akseli Hemminki
Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids.
Cancer gene therapy 2003;10(5):377-87.
2003: Tyler J Curiel; Shuang Wei; Haidong Dong; Xavier Alvarez; Pui Cheng; Peter Mottram; Roman Krzysiek; Keith L Knutson; Ben Daniel; Maria Carla Zimmermann; Odile David; Matthew Burow; Alan Gordon; Nina Dhurandhar; Leann Myers; Ruth Berggren; Akseli Hemminki; Ronald D Alvarez; Dominique Emilie; David T Curiel; Lieping Chen; Weiping Zou
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.
Nature medicine 2003;9(5):562-7.
2003: Shannon D Barker; Candace J Coolidge; Anna Kanerva; Tanja Hakkarainen; Masato Yamamoto; Bin Liu; Angel A Rivera; Snehal M Bhoola; Mack N Barnes; Ronald D Alvarez; David T Curiel; Akseli Hemminki
The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy.
The journal of gene medicine 2003;5(4):300-10.
2003: Yosuke Kawakami; Hui Li; John T Lam; Victor Krasnykh; David T Curiel; Jerry L Blackwell
Substitution of the adenovirus serotype 5 knob with a serotype 3 knob enhances multiple steps in virus replication.
Cancer research 2003;63(6):1262-9.
2003: Waleed O Arafat; Donald J Buchsbaum; Jesús Gómez-Navarro; Sarah A Tawil; Christine Olsen; Jialing Xiang; Hazem El-Akad; Anwar M Salama; Ahmed O Badib; Murray A Stackhouse; David T Curiel
An adenovirus encoding proapoptotic Bax synergistically radiosensitizes malignant glioma.
International journal of radiation oncology, biology, physics 2003;55(4):1037-50.
2003: Peter Nagi; Selwyn M Vickers; Julia Davydova; Yasuo Adachi; Koichi Takayama; Shannon Barker; Victor Krasnykh; David T Curiel; Masato Yamamoto
Development of a therapeutic adenoviral vector for cholangiocarcinoma combining tumor-restricted gene expression and infectivity enhancement.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(3):364-71.
2003: Akseli Hemminki; Anna Kanerva; Bin Liu; Minghui Wang; Ronald D Alvarez; Gene P Siegal; David T Curiel
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research 2003;63(4):847-53.
2003: Akseli Hemminki; Anna Kanerva; Eric J Kremer; Gerd J Bauerschmitz; Bruce F Smith; Bin Liu; Minghui Wang; Renee A Desmond; Anne Keriel; Brian G Barnett; Henry J Baker; Gene P Siegal; David T Curiel
A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(2):163-73.
2003: Tanja Hakkarainen; Akseli Hemminki; Alexander Pereboev; Shannon D Barker; Clement K Asiedu; Theresa V Strong; Anna Kanerva; Jarmo Wahlfors; David T Curiel
CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):619-24.
2003: taco uil; Toshiro Seki; Igor Dmitriev; Elena Kashentseva; Joanne T Douglas; Marianne G Rots; Jaap Middeldorp; David T Curiel
Generation of an adenoviral vector containing an addition of a heterologous ligand to the serotype 3 fiber knob.
Cancer gene therapy 2003;10(2):121-4.
2003: Yosuke Kawakami; Tyler J Curiel; David T Curiel
Cancer gene therapy and immunotherapy.
Cancer chemotherapy and biological response modifiers 2003;21():327-37.
2003: Larisa Pereboeva; Svetlana Komarova; Galina Mikheeva; Victor Krasnykh; David T Curiel
Approaches to utilize mesenchymal progenitor cells as cellular vehicles.
Stem cells (Dayton, Ohio) 2003;21(4):389-404.
2003: Masato Yamamoto; Julia Davydova; Koichi Takayama; Ramon Alemany; David T Curiel
Transcription initiation activity of adenovirus left-end sequence in adenovirus vectors with e1 deleted.
Journal of virology 2003;77(2):1633-7.
2002: Hongju Wu; Igor Dmitriev; Elena Kashentseva; Toshiro Seki; Minghui Wang; David T Curiel
Construction and characterization of adenovirus serotype 5 packaged by serotype 3 hexon.
Journal of virology 2002;76(24):12775-82.
2002: Huang-Ge Zhang; Jinfu Xie; Igor Dmitriev; Elena Kashentseva; David T Curiel; Hui-Chen Hsu; John D Mountz
Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or production.
Journal of virology 2002;76(23):12023-31.
2002: Kaori Suzuki; Ramon Alemany; Masato Yamamoto; David T Curiel
The presence of the adenovirus E3 region improves the oncolytic potency of conditionally replicative adenoviruses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3348-59.
2002: jacques grill; Martine L M Lamfers; Victor W van Beusechem; Clemens M F Dirven; D Shareen Pherai; Mathijs Kater; Paul Van Der Valk; Ronald Vogels; W Peter Vandertop; HERBERT PINEDO; David T Curiel; Winald Gerritsen
The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(5):609-14.
2002: Deborah E Sullivan; Mario U Mondelli; David T Curiel; Victor Krasnykh; Galina Mikheeva; Paul Gaglio; Cindy B Morris; Srikanta Dash; Michael A Gerber
Construction and characterization of an intracellular single-chain human antibody to hepatitis C virus non-structural 3 protein.
Journal of hepatology 2002;37(5):660-8.
2002: Tanja D de Gruijl; Sylvia A Luykx-de Bakker; Bryan W Tillman; Alfons J M van den Eertwegh; Jan Buter; Sinéad M Lougheed; Gerben J van der Bij; A Mahmoud Safer; Hidde J Haisma; David T Curiel; Rik J Scheper; HERBERT PINEDO; Winald Gerritsen
Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5322-31.
2002: Martine L M Lamfers; jacques grill; Clemens M F Dirven; Victor W van Beusechem; Birgit Geoerger; Jaap Van Den Berg; Ramon Alemany; Juan Fueyo; David T Curiel; Gilles Vassal; HERBERT PINEDO; W Peter Vandertop; Winald Gerritsen
Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.
Cancer research 2002;62(20):5736-42.
2002: Guadalupe Bilbao; Juan L Contreras; David T Curiel
Genetically engineered intracellular single-chain antibodies in gene therapy.
Molecular biotechnology 2002;22(2):191-211.
2002: Clement K Asiedu; Sai Sai Dong; Alexander Pereboev; Weila Wang; Jesus Navarro; David T Curiel; Judith M Thomas
Rhesus monocyte-derived dendritic cells modified to over-express TGF-beta1 exhibit potent veto activity.
Transplantation 2002;74(5):629-37.
2002: Robert M Conry; David T Curiel; Theresa V Strong; Susan E Moore; Karen O Allen; Daunte L Barlow; Denise R Shaw; Albert F LoBuglio
Safety and immunogenicity of a DNA vaccine encoding carcinoembryonic antigen and hepatitis B surface antigen in colorectal carcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2782-7.
2002: Brian G Barnett; Bryan W Tillman; David T Curiel; Joanne T Douglas
Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(3):377-85.
2002: Hongju Wu; Toshiro Seki; Igor Dmitriev; taco uil; Elena Kashentseva; Tie Han; David T Curiel
Double modification of adenovirus fiber with RGD and polylysine motifs improves coxsackievirus-adenovirus receptor-independent gene transfer efficiency.
Human gene therapy 2002;13(13):1647-53.
2002: M Adhiambo Witlox; Victor W van Beusechem; jacques grill; Hidde J Haisma; Gerard R Schaap; Johannes Bras; Paulus van Diest; Arthur de Gast; David T Curiel; HERBERT PINEDO; Winald Gerritsen; Paul I J M Wuisman
Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma.
The journal of gene medicine 2002;4(5):510-6.
2002: M Kim; Kurt R Zinn; B G Barnett; Lucretia A Sumerel; Victor Krasnykh; David T Curiel; Joanne T Douglas
The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells.
European journal of cancer (Oxford, England : 1990) 2002;38(14):1917-26.
2002: Alexander Pereboev; Clement K Asiedu; Yosuke Kawakami; Sai Sai Dong; Jerry L Blackwell; Elena Kashentseva; Pierre L Triozzi; Wayne A Aldrich; David T Curiel; Judith M Thomas; Igor Dmitriev
Coxsackievirus-adenovirus receptor genetically fused to anti-human CD40 scFv enhances adenoviral transduction of dendritic cells.
Gene therapy 2002;9(17):1189-93.
2002: Natalya Belousova; Valentina Krendelchtchikova; David T Curiel; Victor Krasnykh
Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.
Journal of virology 2002;76(17):8621-31.
2002: Dirk M Nettelbeck; Angel A Rivera; Cristina Balagué; Ramon Alemany; David T Curiel
Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter.
Cancer research 2002;62(16):4663-70.
2002: Akseli Hemminki; Minghui Wang; Renee A Desmond; Theresa V Strong; Ronald D Alvarez; David T Curiel
Serum and ascites neutralizing antibodies in ovarian cancer patients treated with intraperitoneal adenoviral gene therapy.
Human gene therapy 2002;13(12):1505-14.
2002: Clemens M F Dirven; jacques grill; Martine L M Lamfers; Paul Van Der Valk; Angelique M Leonhart; Victor W van Beusechem; Hidde J Haisma; HERBERT PINEDO; David T Curiel; W Peter Vandertop; Winald Gerritsen
Gene therapy for meningioma: improved gene delivery with targeted adenoviruses.
Journal of neurosurgery 2002;97(2):441-9.
2002: Sergey A Kaliberov; Donald J Buchsbaum; G Yancey Gillespie; David T Curiel; Waleed O Arafat; Mark Carpenter; Murray A Stackhouse
Adenovirus-mediated transfer of BAX driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):190-8.
2002: Yosef S Haviv; Jerry L Blackwell; Anna Kanerva; Peter Nagi; Victor Krasnykh; Igor Dmitriev; Minghui Wang; Seiji Naito; Xiaosheng Lei; Akseli Hemminki; Delicia Carey; David T Curiel
Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors.
Cancer research 2002;62(15):4273-81.
2002: Toshiro Seki; Igor Dmitriev; Kaori Suzuki; Elena Kashentseva; Koichi Takayama; Marianne G Rots; taco uil; Hongju Wu; Minghui Wang; David T Curiel
Fiber shaft extension in combination with HI loop ligands augments infectivity for CAR-negative tumor targets but does not enhance hepatotropism in vivo.
Gene therapy 2002;9(16):1101-8.
2002: Igor Dmitriev; Elena Kashentseva; David T Curiel
Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX.
Journal of virology 2002;76(14):6893-9.
2002: H G van der Poel; Bonnie Molenaar; Victor W van Beusechem; Hidde J Haisma; Ronald Rodriguez; David T Curiel; Winald Gerritsen
Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer.
The Journal of urology 2002;168(1):266-72.
2002: Anna Kanerva; Minghui Wang; Gerd J Bauerschmitz; John T Lam; Renee A Desmond; Snehal M Bhoola; Mack N Barnes; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):695-704.
2002: Huang-Ge Zhang; Jinfu Xie; Liang Xu; Pingar Yang; Xin Xu; Sheher Sun; Yongming Wang; David T Curiel; Hui-Chen Hsu; John D Mountz
Hepatic DR5 induces apoptosis and limits adenovirus gene therapy product expression in the liver.
Journal of virology 2002;76(11):5692-700.
2002: Akseli Hemminki; Kurt R Zinn; Bin Liu; Tandra R Chaudhuri; Renee A Desmond; Buck E Rogers; Mack N Barnes; Ronald D Alvarez; David T Curiel
In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus.
Journal of the National Cancer Institute 2002;94(10):741-9.
2002: Kurt R Zinn; Tandra R Chaudhuri; Victor Krasnykh; Donald J Buchsbaum; Natalya Belousova; William E Grizzle; David T Curiel; Buck E Rogers
Gamma camera dual imaging with a somatostatin receptor and thymidine kinase after gene transfer with a bicistronic adenovirus in mice.
Radiology 2002;223(2):417-25.
2002: Mack N Barnes; Candace J Coolidge; Akseli Hemminki; Ronald D Alvarez; David T Curiel
Conditionally replicative adenoviruses for ovarian cancer therapy.
Molecular cancer therapeutics 2002;1(6):435-9.
2002: Yasuo Adachi; Shyuichiro Matsubara; Takashi Muramatsu; David T Curiel; Paul N Reynolds
Midkine promoter-based adenoviral suicide gene therapy to midkine-positive pediatric tumor.
Journal of pediatric surgery 2002;37(4):588-92.
2002: Per Sonne Holm; Stephan Bergmann; Karsten Jurchott; Hermann Lage; Karsten Brand; Axel Ladhoff; Klaus Mantwill; David T Curiel; Matthias Dobbelstein; Manfred Dietel; Bernd Gansbacher; hans-dieter royer
YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter.
The Journal of biological chemistry 2002;277(12):10427-34.
2002: Yosef S Haviv; Koichi Takayama; Joel N Glasgow; Jerry L Blackwell; Minghui Wang; Xiaosheng Lei; David T Curiel
A model system for the design of armed replicating adenoviruses using p53 as a candidate transgene.
Molecular cancer therapeutics 2002;1(5):321-8.
2002: Guadalupe Bilbao; Juan L Contreras; Igor Dmitriev; Cheryl A Smyth; Stacie Jenkins; Devin E Eckhoff; Francis Thomas; Judith Thomas; David T Curiel
Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(3):237-43.
2002: Gerd J Bauerschmitz; Dirk M Nettelbeck; Anna Kanerva; Andrew H Baker; Akseli Hemminki; Paul N Reynolds; David T Curiel
The flt-1 promoter for transcriptional targeting of teratocarcinoma.
Cancer research 2002;62(5):1271-4.
2002: Gerd J Bauerschmitz; John T Lam; Anna Kanerva; Kaori Suzuki; Dirk M Nettelbeck; Igor Dmitriev; Victor Krasnykh; Galina Mikheeva; Mack N Barnes; Ronald D Alvarez; Peter Dall; Ramon Alemany; David T Curiel; Akseli Hemminki
Treatment of ovarian cancer with a tropism modified oncolytic adenovirus.
Cancer research 2002;62(5):1266-70.
2002: Frank A E Kruyt; David T Curiel
Toward a new generation of conditionally replicating adenoviruses: pairing tumor selectivity with maximal oncolysis.
Human gene therapy 2002;13(4):485-95.
2002: Waleed O Arafat; Jesús Gómez-Navarro; Donald J Buchsbaum; Jialing Xiang; Minghui Wang; Enrique Casado; Shannon D Barker; Parameshwar J Mahasreshti; Hidde J Haisma; Mack N Barnes; Gene P Siegal; Ronald D Alvarez; Akseli Hemminki; Dirk M Nettelbeck; David T Curiel
Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv.
Gene therapy 2002;9(4):256-62.
2002: Tyler J Curiel; David T Curiel
Tumor immunotherapy: inching toward the finish line.
The Journal of clinical investigation 2002;109(3):311-2.
2002: Toshiro Seki; Igor Dmitriev; Elena Kashentseva; Koichi Takayama; Marianne G Rots; Kaori Suzuki; David T Curiel
Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines.
Journal of virology 2002;76(3):1100-8.
2002: Elena Kashentseva; Toshiro Seki; David T Curiel; Igor Dmitriev
Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain.
Cancer research 2002;62(2):609-16.
2002: Asiedu Clement; Alexander Pereboev; David T Curiel; Sai Sai Dong; Anne Hutchings; Judith M Thomas
Converting nonhuman primate dendritic cells into potent antigen-specific cellular immunosuppressants by genetic modification.
Immunologic research 2002;26(1-3):297-302.
2002: Juan L Contreras; Guadalupe Bilbao; Cheryl A Smyth; Devin E Eckhoff; Xiao Ling Jiang; Stacie Jenkins; Francis T Thomas; David T Curiel; Judith M Thomas
Cytoprotection of pancreatic islets before and early after transplantation using gene therapy.
Kidney international 2002;61(1 Suppl):S79-84.
2002: Paul N Reynolds; David T Curiel
New generation adenoviral vectors improve gene transfer by coxsackie and adenoviral receptor-independent cell entry.
Kidney international 2002;61(1 Suppl):S24-31.
2002: Anna Kanerva; Galina Mikheeva; Victor Krasnykh; Candace J Coolidge; John T Lam; Parameshwar J Mahasreshti; Shannon D Barker; Michael Straughn; Mack N Barnes; Ronald D Alvarez; Akseli Hemminki; David T Curiel
Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):275-80.
2001: Hui Li; Yosef S Haviv; Cynthia A Derdeyn; J Lam; Candace J Coolidge; Eric Hunter; David T Curiel; Jerry L Blackwell
Human immunodeficiency virus type 1-mediated syncytium formation is compatible with adenovirus replication and facilitates efficient dispersion of viral gene products and de novo-synthesized virus particles.
Human gene therapy 2001;12(18):2155-65.
2001: John G Wesseling; M Yamamoto; Y Adachi; Piter J Bosma; M van Wijland; Jerry L Blackwell; H Li; Paul N Reynolds; Igor Dmitriev; Selwyn M Vickers; K Huibregtse; David T Curiel
Midkine and cyclooxygenase-2 promoters are promising for adenoviral vector gene delivery of pancreatic carcinoma.
Cancer gene therapy 2001;8(12):990-6.
2001: Yosef S Haviv; Jerry L Blackwell; Hui Li; Minghui Wang; Xiaosheng Lei; David T Curiel
Heat shock and heat shock protein 70i enhance the oncolytic effect of replicative adenovirus.
Cancer research 2001;61(23):8361-5.
2001: Yasuo Adachi; Paul N Reynolds; Masato Yamamoto; Minghui Wang; Koichi Takayama; Shyuichiro Matsubara; Takashi Muramatsu; David T Curiel
A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging.
Cancer research 2001;61(21):7882-8.
2001: Warner K Huh; Jesus Gomez-Navarro; Waleed O Arafat; Jialing Xiang; Parameshwar J Mahasreshti; Ronald D Alvarez; Mack N Barnes; David T Curiel
Bax-induced apoptosis as a novel gene therapy approach for carcinoma of the cervix.
Gynecologic oncology 2001;83(2):370-7.
2001: Selvarangan Ponnazhagan; Gandham Mahendra; David T Curiel; Denise R Shaw
Adeno-associated virus type 2-mediated transduction of human monocyte-derived dendritic cells: implications for ex vivo immunotherapy.
Journal of virology 2001;75(19):9493-501.
2001: Ramon Alemany; David T Curiel
CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors.
Gene therapy 2001;8(17):1347-53.
2001: Akseli Hemminki; Natalya Belousova; Kurt R Zinn; Bin Liu; Minghui Wang; Tandra R Chaudhuri; Buck E Rogers; Donald J Buchsbaum; Gene P Siegal; Mack N Barnes; Jesus Gomez-Navarro; David T Curiel; Ronald D Alvarez
An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(3):223-31.
2001: Paul N Reynolds; S A Nicklin; Lyudmila N Kaliberova; B G Boatman; William E Grizzle; Irina V Balyasnikova; A H Baker; Sergei M Danilov; David T Curiel
Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo.
Nature biotechnology 2001;19(9):838-42.
2001: Akseli Hemminki; Igor Dmitriev; Bin Liu; Renee A Desmond; Ramon Alemany; David T Curiel
Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule.
Cancer research 2001;61(17):6377-81.
2001: Selvarangan Ponnazhagan; David T Curiel; Denise R Shaw; Ronald D Alvarez; Gene P Siegal
Adeno-associated virus for cancer gene therapy.
Cancer research 2001;61(17):6313-21.
2001: Donald J Buchsbaum; David T Curiel
Gene therapy for the treatment of cancer.
Cancer biotherapy & radiopharmaceuticals 2001;16(4):275-88.
2001: Enrique Casado; Dirk M Nettelbeck; Jesus Gomez-Navarro; Akseli Hemminki; Manuel Gonzalez Baron; Gene P Siegal; Mack N Barnes; Ronald D Alvarez; David T Curiel
Transcriptional targeting for ovarian cancer gene therapy.
Gynecologic oncology 2001;82(2):229-37.
2001: Paul N Reynolds; M D Holmes; Y Adachi; Lyudmila N Kaliberova; David T Curiel
A novel system for mitigation of ectopic transgene expression induced by adenoviral vectors.
Gene therapy 2001;8(16):1271-5.
2001: Juan L Contreras; Guadalupe Bilbao; Cheryl A Smyth; Devin E Eckhoff; X L Xiang; Stacie Jenkins; Samuel Cartner; David T Curiel; Francis T Thomas; Judith M Thomas
Gene transfer of the Bcl-2 gene confers cytoprotection to isolated adult porcine pancreatic islets exposed to xenoreactive antibodies and complement.
Surgery 2001;130(2):166-74.
2001: Enrique Casado; Jesus Gomez-Navarro; Masato Yamamoto; Yasuo Adachi; Candace J Coolidge; Waleed O Arafat; Shannon D Barker; Ming H Wang; Parameshwar J Mahasreshti; Akseli Hemminki; Manuel Gonzalez Baron; Mack N Barnes; TB Pustilnik; Gene P Siegal; Ronald D Alvarez; David T Curiel
Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2496-504.
2001: Cristina Balagué; Francisco Noya; Ramon Alemany; Louise T Chow; David T Curiel
Human papillomavirus E6E7-mediated adenovirus cell killing: selectivity of mutant adenovirus replication in organotypic cultures of human keratinocytes.
Journal of virology 2001;75(16):7602-11.
2001: Alexander Pereboev; Larisa Pereboeva; David T Curiel
Phage display of adenovirus type 5 fiber knob as a tool for specific ligand selection and validation.
Journal of virology 2001;75(15):7107-13.
2001: K Suzuki; David T Curiel
[Viral therapy of cancer].
Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición 2001;53(4):346-56.
2001: Parameshwar J Mahasreshti; Jesus Gomez-Navarro; Manjula Kataram; Ming H Wang; Delicia Carey; Gene P Siegal; Mack N Barnes; Dirk M Nettelbeck; Ronald D Alvarez; Akseli Hemminki; David T Curiel
Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):2057-66.
2001: John G Wesseling; Piter J Bosma; Victor Krasnykh; Elena Kashentseva; Jerry L Blackwell; Paul N Reynolds; H Li; M Parameshwar; Selwyn M Vickers; Elizabeth M Jaffee; K Huibregtse; David T Curiel; Igor Dmitriev
Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors.
Gene therapy 2001;8(13):969-76.
2001: Shannon D Barker; Enrique Casado; Jesus Gomez-Navarro; Jialing Xiang; Waleed O Arafat; Parameshwar J Mahasreshti; TB Pustilnik; Akseli Hemminki; Gene P Siegal; Ronald D Alvarez; David T Curiel
An immunomagnetic-based method for the purification of ovarian cancer cells from patient-derived ascites.
Gynecologic oncology 2001;82(1):57-63.
2001: Huang-Ge Zhang; Y M Wang; J F Xie; X Liang; Hui-Chen Hsu; X Zhang; J Douglas; David T Curiel; John D Mountz
Recombinant adenovirus expressing adeno-associated virus cap and rep proteins supports production of high-titer recombinant adeno-associated virus.
Gene therapy 2001;8(9):704-12.
2001: Victor Krasnykh; Natalya Belousova; Nikolay Korokhov; Galina Mikheeva; David T Curiel
Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin.
Journal of virology 2001;75(9):4176-83.
2001: Juan L Contreras; Guadalupe Bilbao; Cheryl A Smyth; Xiao Ling Jiang; Devin E Eckhoff; Sheri M Jenkins; Francis T Thomas; David T Curiel; Judith M Thomas
Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene.
Transplantation 2001;71(8):1015-23.
2001: Y Heike; K Kasono; C Kunisaki; S Hama; N Saijo; T Tsuruo; Douglas A Kuntz; David R Rose; David T Curiel
Overcoming multi-drug resistance using an intracellular anti-MDR1 sFv.
International journal of cancer. Journal international du cancer 2001;92(1):115-22.
2001: jacques grill; Victor W van Beusechem; Paul Van Der Valk; Clemens M F Dirven; A Leonhart; D S Pherai; Hidde J Haisma; HERBERT PINEDO; David T Curiel; Winald Gerritsen
Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):641-50.
2001: Masato Yamamoto; Ramon Alemany; Yasuo Adachi; William E Grizzle; David T Curiel
Characterization of the cyclooxygenase-2 promoter in an adenoviral vector and its application for the mitigation of toxicity in suicide gene therapy of gastrointestinal cancers.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(3):385-94.
2001: Joanne T Douglas; M Kim; Lucretia A Sumerel; Delicia E Carey; David T Curiel
Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary ad receptors.
Cancer research 2001;61(3):813-7.
2001: Kaori Suzuki; J Fueyo; Victor Krasnykh; Paul N Reynolds; David T Curiel; Ramon Alemany
A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(1):120-6.
2000: Victor Krasnykh; Igor Dmitriev; Jesus Gomez-Navarro; Natalya Belousova; Elena Kashentseva; J Xiang; Joanne T Douglas; David T Curiel
Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity.
Cancer research 2000;60(24):6784-7.
2000: Marianne G Rots; David T Curiel
Towards the optimal vector for prostate cancer gene therapy; a caPCURE meeting report.
Cancer gene therapy 2000;7(12):1507-10.
2000: Paul N Reynolds; Kurt R Zinn; Vitaliy Gavrilyuk; Irina V Balyasnikova; Buck E Rogers; Donald J Buchsbaum; M H Wang; DJ Miletich; William E Grizzle; Joanne T Douglas; Sergei M Danilov; David T Curiel
A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(6):562-78.
2000: Waleed O Arafat; Enrique Casado; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel; Jesús Gómez-Navarro
Genetically modified CD34+ cells exert a cytotoxic bystander effect on human endothelial and cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4442-8.
2000: F J Kelly; Ryan Miller; Donald J Buchsbaum; Jesus Gomez-Navarro; Mack N Barnes; Ronald D Alvarez; David T Curiel
Selectivity of TAG-72-targeted adenovirus gene transfer to primary ovarian carcinoma cells versus autologous mesothelial cells in vitro.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4323-33.
2000: Ronald D Alvarez; Jesus Gomez-Navarro; Minghui Wang; Mack N Barnes; Theresa V Strong; Ramin B Arani; Waleed O Arafat; J V Hughes; Gene P Siegal; David T Curiel
Adenoviral-mediated suicide gene therapy for ovarian cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(5):524-30.
2000: Ramon Alemany; K Suzuki; David T Curiel
Blood clearance rates of adenovirus type 5 in mice.
The Journal of general virology 2000;81(Pt 11):2605-9.
2000: Bryan W Tillman; T L Hayes; T D DeGruijl; Joanne T Douglas; David T Curiel
Adenoviral vectors targeted to CD40 enhance the efficacy of dendritic cell-based vaccination against human papillomavirus 16-induced tumor cells in a murine model.
Cancer research 2000;60(19):5456-63.
2000: Waleed O Arafat; Jesús Gómez-Navarro; Jialing Xiang; Gene P Siegal; Ronald D Alvarez; David T Curiel
Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target.
Cancer gene therapy 2000;7(9):1250-6.
2000: David T Curiel
The development of conditionally replicative adenoviruses for cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3395-9.
2000: Yasuo Adachi; Paul N Reynolds; Masato Yamamoto; William E Grizzle; K Overturf; Shyuichiro Matsubara; Takashi Muramatsu; David T Curiel
Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors.
Cancer research 2000;60(16):4305-10.
2000: Jerry L Blackwell; Hui Li; Jesus Gomez-Navarro; Igor Dmitriev; Victor Krasnykh; C A Richter; Denise R Shaw; Ronald D Alvarez; David T Curiel; Theresa V Strong
Using a tropism-modified adenoviral vector to circumvent inhibitory factors in ascites fluid.
Human gene therapy 2000;11(12):1657-69.
2000: David T Curiel; Winald Gerritsen; M R Krul
Progress in cancer gene therapy.
Cancer gene therapy 2000;7(8):1197-9.
2000: Ronald D Alvarez; Mack N Barnes; Jesus Gomez-Navarro; Minghui Wang; Theresa V Strong; Waleed O Arafat; Ramin B Arani; Martin R Johnson; B L Roberts; Gene P Siegal; David T Curiel
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(8):3081-7.
2000: Igor Dmitriev; Elena Kashentseva; Buck E Rogers; Victor Krasnykh; David T Curiel
Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells.
Journal of virology 2000;74(15):6875-84.
2000: Ramon Alemany; Cristina Balagué; David T Curiel
Replicative adenoviruses for cancer therapy.
Nature biotechnology 2000;18(7):723-7.
2000: Waleed O Arafat; Jesús Gómez-Navarro; Jialing Xiang; Mack N Barnes; Parameshwar J Mahasreshti; Ronald D Alvarez; Gene P Siegal; A O Badib; Donald J Buchsbaum; David T Curiel; Murray A Stackhouse
An adenovirus encoding proapoptotic Bax induces apoptosis and enhances the radiation effect in human ovarian cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(6):545-54.
2000: Hidde J Haisma; jacques grill; David T Curiel; S Hoogeland; Victor W van Beusechem; HERBERT PINEDO; Winald Gerritsen
Targeting of adenoviral vectors through a bispecific single-chain antibody.
Cancer gene therapy 2000;7(6):901-4.
2000: Murray A Stackhouse; LC Pederson; William E Grizzle; David T Curiel; Johannes Gebert; K Haack; Selwyn M Vickers; MS Mayo; Donald J Buchsbaum
Fractionated radiation therapy in combination with adenoviral delivery of the cytosine deaminase gene and 5-fluorocytosine enhances cytotoxic and antitumor effects in human colorectal and cholangiocarcinoma models.
Gene therapy 2000;7(12):1019-26.
2000: Jialing Xiang; Jesús Gómez-Navarro; Waleed O Arafat; Bin Liu; Shannon D Barker; Ronald D Alvarez; Gene P Siegal; David T Curiel
Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer.
The journal of gene medicine 2000;2(2):97-106.
2000: T A Hampton; Robert M Conry; Muhammad B Khazaeli; Denise R Shaw; David T Curiel; Albert F LoBuglio; Theresa V Strong
SEREX analysis for tumor antigen identification in a mouse model of adenocarcinoma.
Cancer gene therapy 2000;7(3):446-55.
2000: Guadalupe Bilbao; Jesus Gomez-Navarro; K Kazano; J Luis Contreras; David T Curiel
9 intracellular single-chain antibodies for gene therapy.
Methods in molecular medicine 2000;35():121-49.
2000: David T Curiel
Gene therapy for carcinoma of the breast: Genetic ablation strategies.
Breast cancer research : BCR 2000;2(1):45-9.
2000: David T Curiel
Rational design of viral vectors based on rigorous analysis of capsid structures.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(1):3-4.
2000: Jesús Gómez-Navarro; Juan L Contreras; Waleed O Arafat; Xiao Ling Jiang; David M Krisky; Thomas J Oligino; Pierfrancesco Marconi; B Hubbard; Joseph C Glorioso; David T Curiel; Judith M Thomas
Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model.
Gene therapy 2000;7(1):43-52.
2000: K Kasono; Y Heike; Jialing Xiang; Alain Piché; Hyung-Gyoon Kim; M Kim; M Hagiwara; Michael Nawrath; Karin Moelling; David T Curiel
Tetracycline-induced expression of an anti-c-Myb single-chain antibody and its inhibitory effect on proliferation of the human leukemia cell line K562.
Cancer gene therapy 2000;7(1):151-9.
1999: Ramon Alemany; Candelaria Gomez-Manzano; Cristina Balagué; W K Alfred Yung; David T Curiel; Athanassios P Kyritsis; Juan Fueyo
Gene therapy for gliomas: molecular targets, adenoviral vectors, and oncolytic adenoviruses.
Experimental cell research 1999;252(1):1-12.
1999: Donald J Buchsbaum; Buck E Rogers; Muhammad B Khazaeli; MS Mayo; Diane E Milenic; Syed V S Kashmiri; C J Anderson; Lara L Chappell; Martin W Brechbiel; David T Curiel
Targeting strategies for cancer radiotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3048s-3055s.
1999: K Kasono; Jerry L Blackwell; Joanne T Douglas; Igor Dmitriev; Theresa V Strong; P Reynolds; D A Kropf; William R Carroll; Glenn E Peters; R Pat Bucy; David T Curiel; Victor Krasnykh
Selective gene delivery to head and neck cancer cells via an integrin targeted adenoviral vector.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2571-9.
1999: David T Curiel
Considerations and challenges for the achievement of targeted gene delivery.
Gene therapy 1999;6(9):1497-8.
1999: Hidde J Haisma; HERBERT PINEDO; A Rijswijk; I der Meulen-Muileman; Barbara A Sosnowski; W Ying; V W Beusechem; Bryan W Tillman; Winald Gerritsen; David T Curiel
Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM.
Gene therapy 1999;6(8):1469-74.
1999: Francis T Thomas; Juan L Contreras; Guadalupe Bilbao; Camillo Ricordi; David T Curiel; Judith M Thomas
Anoikis, extracellular matrix, and apoptosis factors in isolated cell transplantation.
Surgery 1999;126(2):299-304.
1999: Guadalupe Bilbao; Juan L Contreras; Devin E Eckhoff; Galina Mikheeva; Victor Krasnykh; Joanne T Douglas; Francis T Thomas; Judith M Thomas; David T Curiel
Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene.
Annals of surgery 1999;230(2):185-93.
1999: Jerry L Blackwell; Ryan Miller; Joanne T Douglas; H Li; Paul N Reynolds; William R Carroll; Glenn E Peters; Theresa V Strong; David T Curiel
Retargeting to EGFR enhances adenovirus infection efficiency of squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery 1999;125(8):856-63.
1999: T J Vanderkwaak; Minghui Wang; Jesús Gómez-Navarro; Claudine Rancourt; Igor Dmitriev; Victor Krasnykh; Mack Barnes; Gene P Siegal; R Alvarez; David T Curiel
An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.
Gynecologic oncology 1999;74(2):227-34.
1999: Guadalupe Bilbao; Juan L Contreras; Huang-Ge Zhang; M J Pike; K Overturf; Galina Mikheeva; Victor Krasnykh; David T Curiel
Adenovirus-mediated gene expression in vivo is enhanced by the antiapoptotic bcl-2 gene.
Journal of virology 1999;73(8):6992-7000.
1999: P Reynolds; Igor Dmitriev; David T Curiel
Insertion of an RGD motif into the HI loop of adenovirus fiber protein alters the distribution of transgene expression of the systemically administered vector.
Gene therapy 1999;6(7):1336-9.
1999: Jesús Gómez-Navarro; David T Curiel; Joanne T Douglas
Gene therapy for cancer.
European journal of cancer (Oxford, England : 1990) 1999;35(6):867-85.
1999: Bryan W Tillman; Tanja D de Gruijl; Sylvia A Luykx-de Bakker; Rik J Scheper; HERBERT PINEDO; Tyler J Curiel; Winald Gerritsen; David T Curiel
Maturation of dendritic cells accompanies high-efficiency gene transfer by a CD40-targeted adenoviral vector.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6378-83.
1999: Murray A Stackhouse; Donald J Buchsbaum; SR Kancharla; William E Grizzle; C Grimes; K Laffoon; L C Pederson; David T Curiel
Specific membrane receptor gene expression targeted with radiolabeled peptide employing the erbB-2 and DF3 promoter elements in adenoviral vectors.
Cancer gene therapy 1999;6(3):209-19.
1999: Joanne T Douglas; Ryan Miller; M Kim; Igor Dmitriev; Galina Mikheeva; Victor Krasnykh; David T Curiel
A system for the propagation of adenoviral vectors with genetically modified receptor specificities.
Nature biotechnology 1999;17(5):470-5.
1999: Z Shi; David T Curiel; De-chu C Tang
DNA-based non-invasive vaccination onto the skin.
Vaccine 1999;17(17):2136-41.
1999: Guadalupe Bilbao; Juan L Contreras; Jesús Gómez-Navarro; Devin E Eckhoff; Galina Mikheeva; Victor Krasnykh; T Hynes; Francis T Thomas; Judith M Thomas; David T Curiel
Genetic modification of liver grafts with an adenoviral vector encoding the Bcl-2 gene improves organ preservation.
Transplantation 1999;67(6):775-83.
1999: Guadalupe Bilbao; Juan L Contreras; Galina Mikheeva; Victor Krasnykh; Devin E Eckhoff; Francis T Thomas; Judith Thomas; David T Curiel
Genetic cytoprotection of human endothelial cells during preservation time with an adenoviral vector encoding the anti-apoptotic human Bcl-2 gene.
Transplantation proceedings 1999;31(1-2):1012-5.
1999: Guadalupe Bilbao; H Zhang; Juan L Contreras; Tong Zhou; M Feng; I Saito; John D Mountz; David T Curiel
Construction of a recombinant adenovirus vector encoding Fas ligand with a CRE/Loxp inducible system.
Transplantation proceedings 1999;31(1-2):792-3.
1999: Buck E Rogers; S F McLean; Richard L Kirkman; Debbie Della Manna; SJ Bright; CC Olsen; Angela Myracle; MS Mayo; David T Curiel; Donald J Buchsbaum
In vivo localization of [(111)In]-DTPA-D-Phe1-octreotide to human ovarian tumor xenografts induced to express the somatostatin receptor subtype 2 using an adenoviral vector.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(2):383-93.
1999: David T Curiel
Strategies to adapt adenoviral vectors for targeted delivery.
Annals of the New York Academy of Sciences 1999;886():158-71.
1999: Paul N Reynolds; M Feng; David T Curiel
Chimeric viral vectors--the best of both worlds?
Molecular medicine today 1999;5(1):25-31.
1999: Claudine Rancourt; Alain Piché; Jesus Gomez-Navarro; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Gerald M Fuller; SA Jones; David T Curiel
Interleukin-6 modulated conditionally replicative adenovirus as an antitumor/cytotoxic agent for cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):43-50.
1998: Ryan Miller; Donald J Buchsbaum; Paul N Reynolds; Joanne T Douglas; G Yancey Gillespie; MS Mayo; David Raben; David T Curiel
Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer.
Cancer research 1998;58(24):5738-48.
1998: Igor Dmitriev; Victor Krasnykh; Ryan Miller; Minghui Wang; Elena Kashentseva; Galina Mikheeva; Natalya Belousova; David T Curiel
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism.
Journal of virology 1998;72(12):9706-13.
1998: T Suzuki; A Piche; K Kasono; Jialing Xiang; Jesus Gomez-Navarro; Shusuke Moriuchi; David M Krisky; Thomas J Oligino; Joseph C Glorioso; Tyler J Curiel; David T Curiel
Efficient gene delivery into epstein-barr virus (EBV)-transformed human B cells mediated by replication-defective herpes simplex virus-1 (HSV-1): A gene therapy model for EBV-related B cell malignancy.
Biochemical and biophysical research communications 1998;252(3):686-90.
1998: Murray A Stackhouse; Donald J Buchsbaum; William E Grizzle; SJ Bright; CC Olsen; SR Kancharla; MS Mayo; David T Curiel
Radiosensitization mediated by a transfected anti-erbB-2 single-chain antibody in vitro and in vivo.
International journal of radiation oncology, biology, physics 1998;42(4):817-22.
1998: Huang-Ge Zhang; Di Liu; Y Heike; Pingar Yang; Z Wang; X Wang; David T Curiel; Tong Zhou; John D Mountz
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells.
Nature biotechnology 1998;16(11):1045-9.
1998: Robert M Conry; S A White; Patricia N Fultz; Muhammad B Khazaeli; Theresa V Strong; Karen O Allen; Daunte L Barlow; Susan E Moore; Pat Coan; I Davis; David T Curiel; Albert F LoBuglio
Polynucleotide immunization of nonhuman primates against carcinoembryonic antigen.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2903-12.
1998: Minghui Wang; Claudine Rancourt; Jesus Gomez-Navarro; David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel
High-efficacy thymidine kinase gene transfer to ovarian cancer cell lines mediated by herpes simplex virus type 1 vector.
Gynecologic oncology 1998;71(2):278-87.
1998: K Kasono; Alain Piché; Jialing Xiang; Hyung-Gyoon Kim; G Bilbao; F Johanning; Michael Nawrath; Karin Moelling; David T Curiel
Functional knock-out of c-myb by an intracellular anti-c-Myb single-chain antibody.
Biochemical and biophysical research communications 1998;251(1):124-30.
1998: Claudine Rancourt; Buck E Rogers; Barbara A Sosnowski; Minghui Wang; Alain Piché; Glenn F Pierce; Ronald D Alvarez; Gene P Siegal; Joanne T Douglas; David T Curiel
Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2455-61.
1998: JE Grim; Gene P Siegal; Ronald D Alvarez; David T Curiel
Intracellular expression of the anti-erbB-2 sFv N29 fails to accomplish efficient target modulation.
Biochemical and biophysical research communications 1998;250(3):699-703.
1998: Alain Piché; K Kasono; F Johanning; Tyler J Curiel; David T Curiel
Phenotypic knock-out of the latent membrane protein 1 of Epstein-Barr virus by an intracellular single-chain antibody.
Gene therapy 1998;5(9):1171-9.
1998: MW Robertson; Minghui Wang; Gene P Siegal; M Rosenfeld; R S Ashford; Ronald D Alvarez; Robert I Garver; David T Curiel
Use of a tissue-specific promoter for targeted expression of the herpes simplex virus thymidine kinase gene in cervical carcinoma cells.
Cancer gene therapy 1998;5(5):331-6.
1998: Huang-Ge Zhang; Tong Zhou; Pingar Yang; Carl K Edwards; David T Curiel; John D Mountz
Inhibition of tumor necrosis factor alpha decreases inflammation and prolongs adenovirus gene expression in lung and liver.
Human gene therapy 1998;9(13):1875-84.
1998: K T Goldsmith; L D Dion; David T Curiel; Robert I Garver
trans E1 component requirements for maximal replication of E1-defective recombinant adenovirus.
Virology 1998;248(2):406-19.
1998: Corey K Goldman; R L Kendall; G Cabrera; Liliana Soroceanu; Yuji Heike; G Y Gillespie; G P Siegal; Xianzhi Mao; Andrew J Bett; William R Huckle; Kenneth Thomas; David T Curiel
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8795-800.
1998: Bruce F Smith; Henry J Baker; David T Curiel; W Jiang; R M Conry
Humoral and cellular immune responses of dogs immunized with a nucleic acid vaccine encoding human carcinoembryonic antigen.
Gene therapy 1998;5(7):865-8.
1998: Kurt R Zinn; Joanne T Douglas; C A Smyth; Hong-Gang Liu; Qi Wu; Victor Krasnykh; John D Mountz; David T Curiel; James M Mountz
Imaging and tissue biodistribution of 99mTc-labeled adenovirus knob (serotype 5).
Gene therapy 1998;5(6):798-808.
1998: MW Robertson; Mack N Barnes; Claudine Rancourt; Minghui Wang; JE Grim; Ronald D Alvarez; Gene P Siegal; David T Curiel
Gene therapy for ovarian carcinoma.
Seminars in oncology 1998;25(3):397-406.
1998: Alain Piché; JE Grim; Claudine Rancourt; Jesús Gómez-Navarro; J C Reed; David T Curiel
Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7.
Cancer research 1998;58(10):2134-40.
1998: LC Pederson; Selwyn M Vickers; Donald J Buchsbaum; SR Kancharla; MS Mayo; David T Curiel; Murray A Stackhouse
Combined cytosine deaminase expression, 5-fluorocytosine exposure, and radiotherapy increases cytotoxicity to cholangiocarcinoma cells.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 1998;2(3):283-91.
1998: JE Grim; Jessy Deshane; Gene P Siegal; Ronald D Alvarez; P DiFiore; David T Curiel
The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv.
Journal of molecular medicine (Berlin, Germany) 1998;76(6):451-8.
1998: JA Campain; Angela A Matassa; P L Felgner; K M Barnhart; David T Curiel; Gail S Harrison
Lipid- and adenoviral-mediated gene transfer into AIDS-Kaposi's sarcoma cell lines.
Cancer gene therapy 1998;5(3):131-43.
1998: Feng Wang-Johanning; G Yancey Gillespie; JE Grim; Claudine Rancourt; Ronald D Alvarez; Gene P Siegal; David T Curiel
Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects.
Cancer research 1998;58(9):1893-900.
1998: Jesús Gómez-Navarro; Gene P Siegal; Ronald D Alvarez; David T Curiel
Gene therapy: ovarian carcinoma as the paradigm.
American journal of clinical pathology 1998;109(4):444-67.
1998: Huang-Ge Zhang; Guadalupe Bilbao; Tong Zhou; Juan L Contreras; Jesús Gómez-Navarro; M Feng; I Saito; John D Mountz; David T Curiel
Application of a Fas ligand encoding a recombinant adenovirus vector for prolongation of transgene expression.
Journal of virology 1998;72(3):2483-90.
1998: Victor Krasnykh; Igor Dmitriev; Galina Mikheeva; Ryan Miller; Natalya Belousova; David T Curiel
Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob.
Journal of virology 1998;72(3):1844-52.
1998: Claudine Rancourt; MW Robertson; Minghui Wang; CK Goldman; J F Kelly; Ronald D Alvarez; Gene P Siegal; David T Curiel
Endothelial cell vehicles for delivery of cytotoxic genes as a gene therapy approach for carcinoma of the ovary.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):265-70.
1997: Buck E Rogers; David T Curiel; MS Mayo; K K Laffoon; SJ Bright; Donald J Buchsbaum
Tumor localization of a radiolabeled bombesin analogue in mice bearing human ovarian tumors induced to express the gastrin-releasing peptide receptor by an adenoviral vector.
Cancer 1997;80(12 Suppl):2419-24.
1997: Buck E Rogers; Joanne T Douglas; Clarence Ahlem; Donald J Buchsbaum; James M Frincke; David T Curiel
Use of a novel cross-linking method to modify adenovirus tropism.
Gene therapy 1997;4(12):1387-92.
1997: Tyler J Curiel; Alain Piché; K Kasono; David T Curiel
Gene therapy strategies for AIDS-related malignancies.
Gene therapy 1997;4(12):1284-8.
1997: De-chu C Tang; R S Jennelle; Z Shi; Robert I Garver; D P Carbone; F Loya; C H Chang; David T Curiel
Overexpression of adenovirus-encoded transgenes from the cytomegalovirus immediate early promoter in irradiated tumor cells.
Human gene therapy 1997;8(17):2117-24.
1997: LC Pederson; Donald J Buchsbaum; Selwyn M Vickers; SR Kancharla; MS Mayo; David T Curiel; Murray A Stackhouse
Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo.
Cancer research 1997;57(19):4325-32.
1997: M Feng; WH Jackson; CK Goldman; Claudine Rancourt; M Wang; S K Dusing; G Siegal; David T Curiel
Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector.
Nature biotechnology 1997;15(9):866-70.
1997: Selwyn M Vickers; L S Sampson; JO Phillips; D Eckhoff; Jeffrey D Kerby; MC Sekar; David T Curiel; John A Thompson
Adenoviral vector infection of the human exocrine pancreas.
Archives of surgery (Chicago, Ill. : 1960) 1997;132(9):1006-9.
1997: Buck E Rogers; ME Rosenfeld; Muhammad B Khazaeli; Galina Mikheeva; Murray A Stackhouse; T Liu; David T Curiel; Donald J Buchsbaum
Localization of iodine-125-mIP-Des-Met14-bombesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(8):1221-9.
1997: ME Rosenfeld; Buck E Rogers; Muhammad B Khazaeli; Galina Mikheeva; D Raben; M S Mayo; David T Curiel; Donald J Buchsbaum
Adenoviral-mediated delivery of gastrin-releasing peptide receptor results in specific tumor localization of a bombesin analogue in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(7):1187-94.
1997: Joanne T Douglas; David T Curiel
Strategies to accomplish targeted gene delivery to muscle cells employing tropism-modified adenoviral vectors.
Neuromuscular disorders : NMD 1997;7(5):284-98.
1997: Guadalupe Bilbao; M Feng; Claudine Rancourt; WH Jackson; David T Curiel
Adenoviral/retroviral vector chimeras: a novel strategy to achieve high-efficiency stable transduction in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(8):624-34.
1997: J Michael Ruppert; M Wright; M Rosenfeld; J Grushcow; G Bilbao; David T Curiel; Theresa V Strong
Gene therapy strategies for carcinoma of the breast.
Breast cancer research and treatment 1997;44(2):93-114.
1997: Theresa V Strong; T A Hampton; Iuri D Louro; G Bilbao; Robert M Conry; David T Curiel
Incorporation of beta-globin untranslated regions into a Sindbis virus vector for augmentation of heterologous mRNA expression.
Gene therapy 1997;4(6):624-7.
1997: ME Rosenfeld; S M Vickers; D Raben; M Wang; L Sampson; M Feng; Elizabeth M Jaffee; David T Curiel
Pancreatic carcinoma cell killing via adenoviral mediated delivery of the herpes simplex virus thymidine kinase gene.
Annals of surgery 1997;225(5):609-18; discussion 618-20.
1997: CK Goldman; Liliana Soroceanu; N Smith; G Yancey Gillespie; W Shaw; S Burgess; G Bilbao; David T Curiel
In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer.
Nature biotechnology 1997;15(5):462-6.
1997: C K Goldman; Buck E Rogers; Joanne T Douglas; Barbara A Sosnowski; W Ying; Gene P Siegal; Andrew Baird; J A Campain; David T Curiel
Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor.
Cancer research 1997;57(8):1447-51.
1997: Larry McDaniel; F Loechel; C Benedict; TE Greenway; D E Briles; Robert M Conry; David T Curiel
Immunization with a plasmid expressing pneumococcal surface protein A (PspA) can elicit protection against fatal infection with Streptococcus pneumoniae.
Gene therapy 1997;4(4):375-7.
1997: Marcienne Wright; JE Grim; Jessy Deshane; M Kim; Theresa V Strong; Gene P Siegal; David T Curiel
An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2.
Gene therapy 1997;4(4):317-22.
1997: Jessy Deshane; Gene P Siegal; Minghui Wang; Marcienne Wright; R Pat Bucy; Ronald D Alvarez; David T Curiel
Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy.
Gynecologic oncology 1997;64(3):378-85.
1997: M Kim; Marcienne Wright; Jessy Deshane; Mary Ann Accavitti; Arabella B Tilden; M Saleh; William P Vaughan; Matthew H Carabasi; M D Rogers; RD Hockett; William E Grizzle; David T Curiel
A novel gene therapy strategy for elimination of prostate carcinoma cells from human bone marrow.
Human gene therapy 1997;8(2):157-70.
1997: David T Curiel
Targeted tumor cytotoxicity mediated by intracellular single-chain anti-oncogene antibodies.
Advances in pharmacology (San Diego, Calif.) 1997;40():51-84.
1997: Mack N Barnes; Jessy Deshane; M Rosenfeld; Gene P Siegal; David T Curiel; Ronald D Alvarez
Gene therapy and ovarian cancer: a review.
Obstetrics and gynecology 1997;89(1):145-55.
1996: Donald J Buchsbaum; David Raben; Murray A Stackhouse; Muhammad B Khazaeli; Buck E Rogers; M E Rosenfeld; T Liu; David T Curiel
Approaches to enhance cancer radiotherapy employing gene transfer methods.
Gene therapy 1996;3(12):1042-68.
1996: Joanne T Douglas; Buck E Rogers; M E Rosenfeld; S I Michael; M Feng; David T Curiel
Targeted gene delivery by tropism-modified adenoviral vectors.
Nature biotechnology 1996;14(11):1574-8.
1996: L D Dion; K T Goldsmith; Theresa V Strong; Guadalupe Bilbao; David T Curiel; Robert I Garver
E1A RNA transcripts amplify adenovirus-mediated tumor reduction.
Gene therapy 1996;3(11):1021-5.
1996: Victor Krasnykh; Galina Mikheeva; Joanne T Douglas; David T Curiel
Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.
Journal of virology 1996;70(10):6839-46.
1996: Selwyn M Vickers; JO Phillips; Jeffrey D Kerby; John S Bynon; John A Thompson; David T Curiel
In vivo gene transfer to the human biliary tract.
Gene therapy 1996;3(9):825-8.
1996: JE Grim; Jessy Deshane; M Feng; A Lieber; M Kay; David T Curiel
erbB-2 knockout employing an intracellular single-chain antibody (sFv) accomplishes specific toxicity in erbB-2-expressing lung cancer cells.
American journal of respiratory cell and molecular biology 1996;15(3):348-54.
1996: M E Rosenfeld; Minghui Wang; Gene P Siegal; Ronald D Alvarez; Galina Mikheeva; Victor Krasnykh; David T Curiel
Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma.
Journal of molecular medicine (Berlin, Germany) 1996;74(8):455-62.
1996: ST Zeigler; Jeffrey D Kerby; David T Curiel; J N Wehby; Arnold G Diethelm; John A Thompson
Molecular conjugate-mediated gene transfer in renal transplantation.
Transplantation proceedings 1996;28(4):2046-8.
1996: Mack N Barnes; Jessy Deshane; Gene P Siegal; Ronald D Alvarez; David T Curiel
Novel gene therapy strategy to accomplish growth factor modulation induces enhanced tumor cell chemosensitivity.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(7):1089-95.
1996: David Raben; Donald J Buchsbaum; Muhammad B Khazaeli; M E Rosenfeld; G Yancey Gillespie; W E Grizzle; T Liu; David T Curiel
Enhancement of radiolabeled antibody binding and tumor localization through adenoviral transduction of the human carcinoembryonic antigen gene.
Gene therapy 1996;3(7):567-80.
1996: Scot W Ebbinghaus; Nadarajah Vigneswaran; Ryan Miller; R A Chee-Awai; C A Mayfield; David T Curiel; Donald M Miller
Efficient delivery of triplex forming oligonucleotides to tumor cells by adenovirus-polylysine complexes.
Gene therapy 1996;3(4):287-97.
1996: ST Zeigler; Jeffrey D Kerby; David T Curiel; Arnold G Diethelm; John A Thompson
Molecular conjugate-mediated gene transfer into isolated human kidneys.
Transplantation 1996;61(5):812-7.
1996: Jessy Deshane; JE Grim; S Loechel; Gene P Siegal; Ronald D Alvarez; David T Curiel
Intracellular antibody against erbB-2 mediates targeted tumor cell eradication by apoptosis.
Cancer gene therapy 1996;3(2):89-98.
1996: R M Conry; A F LoBuglio; David T Curiel
Polynucleotide-mediated immunization therapy of cancer.
Seminars in oncology 1996;23(1):135-47.
1996: Robert M Conry; Georg Widera; Albert F LoBuglio; James T Fuller; Susan E Moore; Daunte L Barlow; J Turner; N S Yang; David T Curiel
Selected strategies to augment polynucleotide immunization.
Gene therapy 1996;3(1):67-74.
1996: M E Rosenfeld; David T Curiel
Gene therapy strategies for novel cancer therapeutics.
Current opinion in oncology 1996;8(1):72-7.
1996: David T Curiel; J M Pilewski; S M Albelda
Gene therapy approaches for inherited and acquired lung diseases.
American journal of respiratory cell and molecular biology 1996;14(1):1-18.
1995: M E Rosenfeld; M Feng; S I Michael; Gene P Siegal; Ronald D Alvarez; David T Curiel
Adenoviral-mediated delivery of the herpes simplex virus thymidine kinase gene selectively sensitizes human ovarian carcinoma cells to ganciclovir.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1571-80.
1995: Jessy Deshane; Gene P Siegal; Ronald D Alvarez; M H Wang; M Feng; G Cabrera; T Liu; M Kay; David T Curiel
Targeted tumor killing via an intracellular antibody against erbB-2.
The Journal of clinical investigation 1995;96(6):2980-9.
1995: S I Michael; J S Hong; David T Curiel; Jeffrey A Engler
Addition of a short peptide ligand to the adenovirus fiber protein.
Gene therapy 1995;2(9):660-8.
1995: Jessy Deshane; G Cabrera; JE Grim; Gene P Siegal; J Pike; Ronald D Alvarez; David T Curiel
Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody.
Gynecologic oncology 1995;59(1):8-14.
1995: M Feng; G Cabrera; Jessy Deshane; K J Scanlon; David T Curiel
Neoplastic reversion accomplished by high efficiency adenoviral-mediated delivery of an anti-ras ribozyme.
Cancer research 1995;55(10):2024-8.
1995: F W Johanning; Robert M Conry; Albert F LoBuglio; M Wright; L A Sumerel; M J Pike; David T Curiel
A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo.
Nucleic acids research 1995;23(9):1495-501.
1995: Robert M Conry; Albert F LoBuglio; M Wright; L Sumerel; M J Pike; F Johanning; R Benjamin; D Lu; David T Curiel
Characterization of a messenger RNA polynucleotide vaccine vector.
Cancer research 1995;55(7):1397-400.
1995: Robert M Conry; Albert F LoBuglio; F Loechel; Susan E Moore; L A Sumerel; Daunte L Barlow; J Pike; David T Curiel
A carcinoembryonic antigen polynucleotide vaccine for human clinical use.
Cancer gene therapy 1995;2(1):33-8.
1995: Robert M Conry; Albert F LoBuglio; F Loechel; Susan E Moore; L A Sumerel; Daunte L Barlow; David T Curiel
A carcinoembryonic antigen polynucleotide vaccine has in vivo antitumor activity.
Gene therapy 1995;2(1):59-65.
1994: D Lu; R Benjamin; M Kim; Robert M Conry; David T Curiel
Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors.
Cancer gene therapy 1994;1(4):245-52.
1994: K T Goldsmith; David T Curiel; Jeffrey A Engler; Robert I Garver
Trans complementation of an E1A-deleted adenovirus with codelivered E1A sequences to make recombinant adenoviral producer cells.
Human gene therapy 1994;5(11):1341-8.
1994: Jessy Deshane; F Loechel; Robert M Conry; Gene P Siegal; C R King; David T Curiel
Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines.
Gene therapy 1994;1(5):332-7.
1994: S I Michael; David T Curiel
Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway.
Gene therapy 1994;1(4):223-32.
1994: David T Curiel
High-efficiency gene transfer mediated by adenovirus-polylysine-DNA complexes.
Annals of the New York Academy of Sciences 1994;716():36-56; discussion 56-8.
1994: David T Curiel
High-efficiency gene transfer employing adenovirus-polylysine-DNA complexes.
Natural immunity 1994;13(2-3):141-64.
1994: Robert M Conry; Albert F LoBuglio; Judith A Kantor; Jeffrey Schlom; F Loechel; Susan E Moore; L A Sumerel; Daunte L Barlow; Scott Abrams; David T Curiel
Immune response to a carcinoembryonic antigen polynucleotide vaccine.
Cancer research 1994;54(5):1164-8.
1994: Tyler J Curiel; D R Cook; C Bogedain; Wolfgang Jilg; Gail S Harrison; M Cotten; David T Curiel; Ernst Wagner
Efficient foreign gene expression in Epstein-Barr virus-transformed human B-cells.
Virology 1994;198(2):577-85.
1994: M J Smith; Matthew Rousculp; K T Goldsmith; David T Curiel; Robert I Garver
Surfactant protein A-directed toxin gene kills lung cancer cells in vitro.
Human gene therapy 1994;5(1):29-35.
1994: D R Cook; Ian H Maxwell; L Michael Glode; Françoise Maxwell; J O Stevens; M B Purner; Ernst Wagner; David T Curiel; Tyler J Curiel
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
Cancer biotherapy 1994;9(2):131-41.
1994: Robert I Garver; K T Goldsmith; B Rodu; P C Hu; Eric J Sorscher; David T Curiel
Strategy for achieving selective killing of carcinomas.
Gene therapy 1994;1(1):46-50.