Salvatore Cuzzocrea

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Doyle T; Bryant L; Batinic-Haberle I; Little J; Cuzzocrea S; Masini E; Spasojevic I; Salvemini D
Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance.
Genovese Tiziana; Melani Alessia; Esposito Emanuela; Mazzon Emanuela; Di Paola Rosanna; Bramanti Placido; Pedata Felicita; Cuzzocrea Salvatore
The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord.
Kumar Sanjeev; Allen David A; Kieswich Julius E; Patel Nimesh S A; Harwood Steven; Mazzon Emanuela; Cuzzocrea Salvatore; Raftery Martin J; Thiemermann Christoph; Yaqoob Muhammad M
Dexamethasone ameliorates renal ischemia-reperfusion injury.

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All Publications

2009: Doyle T; Bryant L; Batinic-Haberle I; Little J; Cuzzocrea S; Masini E; Spasojevic I; Salvemini D
Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance.
Neuroscience 2009;164(2):702-10.
2009: Genovese Tiziana; Melani Alessia; Esposito Emanuela; Mazzon Emanuela; Di Paola Rosanna; Bramanti Placido; Pedata Felicita; Cuzzocrea Salvatore
The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord.
Shock (Augusta, Ga.) 2009;32(6):578-85.
2009: Kumar Sanjeev; Allen David A; Kieswich Julius E; Patel Nimesh S A; Harwood Steven; Mazzon Emanuela; Cuzzocrea Salvatore; Raftery Martin J; Thiemermann Christoph; Yaqoob Muhammad M
Dexamethasone ameliorates renal ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN 2009;20(11):2412-25.
2009: Babu Benoy I; Malleo Giuseppe; Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Crisafulli Concetta; Caminiti Rocco; Siriwardena Ajith K; Cuzzocrea Salvatore
Green tea polyphenols ameliorate pancreatic injury in cerulein-induced murine acute pancreatitis.
Pancreas 2009;38(8):954-67.
2009: De Palma Clara; Di Paola Rosanna; Perrotta Cristiana; Mazzon Emanuela; Cattaneo Dario; Trabucchi Emilio; Cuzzocrea Salvatore; Clementi Emilio
Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;60(4):221-8.
2009: Crisafulli Concetta; Galuppo Maria; Cuzzocrea Salvatore
Effects of genetic and pharmacological inhibition of TNF-alpha in the regulation of inflammation in macrophages.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;60(4):332-40.
2009: Mondello Stefania; Mazzon Emanuela; Di Paola Rosanna; Crisafulli Concetta; Mondello Paolo; Buemi Michele; Aloisi Carmelo; Cuzzocrea Salvatore
Thalidomide suppresses sclerosing encapsulating peritonitis in a rat experimental model.
Shock (Augusta, Ga.) 2009;32(3):332-9.
2009: Bryant Leesa; Doyle Tim; Chen Zhoumo; Cuzzocrea Salvatore; Masini Emanuela; Vinci M Cristina; Esposito Emanuela; Mazzon Emanuela; Petrusca Daniela Nicoleta; Petrache Irina; Salvemini Daniela
Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance.
Neuroscience letters 2009;463(1):49-53.
2009: Mazzon Emanuela; Crisafulli Concetta; Galuppo Maria; Cuzzocrea Salvatore
Role of peroxisome proliferator-activated receptor-alpha in ileum tight junction alteration in mouse model of restraint stress.
American journal of physiology. Gastrointestinal and liver physiology 2009;297(3):G488-505.
2009: Ceruti Stefania; Villa Giovanni; Genovese Tiziana; Mazzon Emanuela; Longhi Renato; Rosa Patrizia; Bramanti Placido; Cuzzocrea Salvatore; Abbracchio Maria P
The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury.
Brain : a journal of neurology 2009;132(Pt 8):2206-18.
2009: Marino Angela; Di Paola Rosanna; Crisafulli Concetta; Mazzon Emanuela; Morabito Rossana; Paterniti Irene; Galuppo Maria; Genovese Tiziana; La Spada Giuseppina; Cuzzocrea Salvatore
Protective effect of melatonin against the inflammatory response elicited by crude venom from isolated nematocysts of Pelagia noctiluca (Cnidaria, Scyphozoa).
Journal of pineal research 2009;47(1):56-69.
2009: Paterniti Irene; Genovese Tiziana; Crisafulli Concetta; Mazzon Emanuela; Di Paola Rosanna; Galuppo Maria; Bramanti Placido; Cuzzocrea Salvatore
Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma.
Naunyn-Schmiedeberg's archives of pharmacology 2009;380(2):179-92.
2009: Bucolo Claudio; Ward Keith W; Mazzon Emanuela; Cuzzocrea Salvatore; Drago Filippo
Protective effects of a coumarin derivative in diabetic rats.
Investigative ophthalmology & visual science 2009;50(8):3846-52.
2009: Genovese Tiziana; Esposito Emanuela; Mazzon Emanuela; Di Paola Rosanna; Meli Rosaria; Caminiti Rocco; Bramanti Placido; Fink Mitchell P; Cuzzocrea Salvatore
Beneficial effects of ethyl pyruvate in a mouse model of spinal cord injury.
Shock (Augusta, Ga.) 2009;32(2):217-27.
2009: Crisafulli Concetta; Cuzzocrea Salvatore
The role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor alpha (PPAR-alpha) in the regulation of inflammation in macrophages.
Shock (Augusta, Ga.) 2009;32(1):62-73.
2009: Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Di Paola Rosanna; Murthy Kanneganti; Neville Lewis; Bramanti Placido; Cuzzocrea Salvatore
Effects of a metalloporphyrinic peroxynitrite decomposition catalyst, ww-85, in a mouse model of spinal cord injury.
Free radical research 2009;43(7):631-45.
2009: Iacono Anna; Bianco Giuseppe; Mattace Raso Giuseppina; Esposito Emanuela; d'Emmanuele di Villa Bianca Roberta; Sorrentino Raffaella; Cuzzocrea Salvatore; Calignano Antonio; Autore Giuseppina; Meli Rosaria
Maternal adaptation in pregnant hypertensive rats: improvement of vascular and inflammatory variables and oxidative damage in the kidney.
American journal of hypertension 2009;22(7):777-83.
2009: Mazzon Emanuela; Esposito Emanuela; Di Paola Rosanna; Riccardi Luisa; Caminiti Rocco; Dal Toso Roberto; Pressi Giovanna; Cuzzocrea Salvatore
Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitis.
Naunyn-Schmiedeberg's archives of pharmacology 2009;380(1):79-94.
2009: Failla Marco; Genovese Tiziana; Mazzon Emanuela; Fruciano Mary; Fagone Evelina; Gili Elisa; Barera Annalisa; La Rosa Cristina; Conte Enrico; Crimi Nunzio; Cuzzocrea Salvatore; Vancheri Carlo
16,16-Dimethyl prostaglandin E2 efficacy on prevention and protection from bleomycin-induced lung injury and fibrosis.
American journal of respiratory cell and molecular biology 2009;41(1):50-8.
2009: Esposito Emanuela; Cuzzocrea Salvatore
Role of nitroso radicals as drug targets in circulatory shock.
British journal of pharmacology 2009;157(4):494-508.
2009: D'Agostino Giuseppe; La Rana Giovanna; Russo Roberto; Sasso Oscar; Iacono Anna; Esposito Emanuela; Mattace Raso Giuseppina; Cuzzocrea Salvatore; Loverme Jesse; Piomelli Daniele; Meli Rosaria; Calignano Antonio
Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia.
European journal of pharmacology 2009;613(1-3):54-9.
2009: Cuzzocrea Salvatore; Deigner Hans-Peter; Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Crisafulli Concetta; Di Paola Rosanna; Bramanti Placido; Matuschak George; Salvemini Daniela
Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury.
Shock (Augusta, Ga.) 2009;31(6):634-44.
2009: Genovese Tiziana; Esposito Emanuela; Mazzon Emanuela; Crisafulli Concetta; Paterniti Irene; Di Paola Rosanna; Galuppo Maria; Bramanti Placido; Cuzzocrea Salvatore
PPAR-alpha modulate the anti-inflammatory effect of glucocorticoids in the secondary damage in experimental spinal cord trauma.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;59(5):338-50.
2009: Esposito Emanuela; Iacono Anna; Bianco Giuseppe; Autore Giuseppina; Cuzzocrea Salvatore; Vajro Pietro; Canani Roberto Berni; Calignano Antonio; Raso Giuseppina Mattace; Meli Rosaria
Probiotics reduce the inflammatory response induced by a high-fat diet in the liver of young rats.
The Journal of nutrition 2009;139(5):905-11.
2009: Rossi Antonietta; Cuzzocrea Salvatore; Sautebin Lidia
Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock.
Current vascular pharmacology 2009;7(2):185-97.
2009: Rossi Antonietta; Di Paola Rosanna; Mazzon Emanuela; Genovese Tiziana; Caminiti Rocco; Bramanti Placido; Pergola Carlo; Koeberle Andreas; Werz Oliver; Sautebin Lidia; Cuzzocrea Salvatore
Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo.
The Journal of pharmacology and experimental therapeutics 2009;329(1):76-86.
2009: Ndengele Michael M; Cuzzocrea Salvatore; Masini Emanuela; Vinci M Cristina; Esposito Emanuela; Muscoli Carolina; Petrusca Daniela Nicoleta; Mollace Vincenzo; Mazzon Emanuela; Li Dechun; Petrache Irina; Matuschak George M; Salvemini Daniela
Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation.
The Journal of pharmacology and experimental therapeutics 2009;329(1):64-75.
2009: Di Paola Rosanna; Menegazzi Marta; Mazzon Emanuela; Genovese Tiziana; Crisafulli Concetta; Dal Bosco Martina; Zou Zhenzhen; Suzuki Hisanori; Cuzzocrea Salvatore
Protective effects of glycyrrhizin in a gut hypoxia (ischemia)-reoxygenation (reperfusion) model.
Intensive care medicine 2009;35(4):687-97.
2009: Genovese Tiziana; Menegazzi Marta; Mazzon Emanuela; Crisafulli Concetta; Di Paola Rosanna; Dal Bosco Martina; Zou Zhenzhen; Suzuki Hisanori; Cuzzocrea Salvatore
Glycyrrhizin reduces secondary inflammatory process after spinal cord compression injury in mice.
Shock (Augusta, Ga.) 2009;31(4):367-75.
2009: Genovese Tiziana; Esposito Emanuela; Mazzon Emanuela; Di Paola Rosanna; Caminiti Rocco; Bramanti Placido; Cappelani Alessandro; Cuzzocrea Salvatore
Absence of endogenous interleukin-10 enhances secondary inflammatory process after spinal cord compression injury in mice.
Journal of neurochemistry 2009;108(6):1360-72.
2009: Di Paola Rosanna; Esposito Emanuela; Mazzon Emanuela; Riccardi Luisa; Caminiti Rocco; Dal Toso Roberto; Pressi Giovanna; Cuzzocrea Salvatore
Teupolioside, a phenylpropanoid glycosides of Ajuga reptans, biotechnologically produced by IRBN22 plant cell line, exerts beneficial effects on a rodent model of colitis.
Biochemical pharmacology 2009;77(5):845-57.
2009: Riccardi Luisa; Mazzon Emanuela; Bruscoli Stefano; Esposito Emanuela; Crisafulli Concetta; Di Paola Rosanna; Caminiti Rocco; Riccardi Carlo; Cuzzocrea Salvatore
Peroxisome proliferator-activated receptor-alpha modulates the anti-inflammatory effect of glucocorticoids in a model of inflammatory bowel disease in mice.
Shock (Augusta, Ga.) 2009;31(3):308-16.
2009: Sivarajah Ahila; Collino Massimo; Yasin Mohammed; Benetti Elisa; Gallicchio Margherita; Mazzon Emanuela; Cuzzocrea Salvatore; Fantozzi Roberto; Thiemermann Christoph
Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R.
Shock (Augusta, Ga.) 2009;31(3):267-74.
2009: Raso Giuseppina Mattace; Esposito Emanuela; Iacono Anna; Pacilio Maria; Cuzzocrea Salvatore; Canani Roberto Berni; Calignano Antonio; Meli Rosaria
Comparative therapeutic effects of metformin and vitamin E in a model of non-alcoholic steatohepatitis in the young rat.
European journal of pharmacology 2009;604(1-3):125-31.
2009: Mondello Stefania; Mazzon Emanuela; Di Paola Rosanna; Crisafulli Concetta; Italiano Domenico; Buemi Michele; Aloisi Calmela; Cuzzocrea Salvatore
Erythropoietin suppresses peritoneal fibrosis in rat experimental model.
European journal of pharmacology 2009;604(1-3):138-49.
2009: Patel Nimesh S A; di Paola Rosanna; Mazzon Emanuela; Britti Domenico; Thiemermann Christoph; Cuzzocrea Salvatore
Peroxisome proliferator-activated receptor-alpha contributes to the resolution of inflammation after renal ischemia/reperfusion injury.
The Journal of pharmacology and experimental therapeutics 2009;328(2):635-43.
2009: Cannarile Lorenza; Cuzzocrea Salvatore; Santucci Luca; Agostini Massimiliano; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Coppo Maddalena; Di Paola Rosanna; Riccardi Carlo
Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis.
Gastroenterology 2009;136(2):530-41.
2009: Cuzzocrea Salvatore; Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Crisafulli Concetta; Di Paola Rosanna; Bramanti Placido; Salvemini Daniela
Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice.
Shock (Augusta, Ga.) 2009;31(2):170-7.
2009: Di Paola Rosanna; Mazzon Emanuela; Genovese Tiziana; Crisafulli Concetta; Bramanti Placido; Caminiti Rocco; Esposito Emanuela; Fink Mitchell P; Cuzzocrea Salvatore
Ethyl pyruvate reduces the development of zymosan-induced generalized inflammation in mice.
Critical care medicine 2009;37(1):270-82.
2009: Batinic-Haberle Ines; Cuzzocrea Salvatore; Rebouças Júlio S; Ferrer-Sueta Gerardo; Mazzon Emanuela; Di Paola Rosanna; Radi Rafael; Spasojevic Ivan; Benov Ludmil; Salvemini Daniela
Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.
Free radical biology & medicine 2009;46(2):192-201.
2009: Batinic-Haberle Ines; Ndengele Michael M; Cuzzocrea Salvatore; Rebouças Júlio S; Spasojevic Ivan; Salvemini Daniela
Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.
Free radical biology & medicine 2009;46(2):212-9.
2009: Esposito E; Cuzzocrea S
TNF-alpha as a therapeutic target in inflammatory diseases, ischemia-reperfusion injury and trauma.
Current medicinal chemistry 2009;16(24):3152-67.
2009: Esposito Emanuela; Cuzzocrea Salvatore
Superoxide, NO, peroxynitrite and PARP in circulatory shock and inflammation.
Frontiers in bioscience : a journal and virtual library 2009;14():263-96.
2008: Mangano K; Sardesai N Y; Quattrocchi C; Mazzon E; Cuzzocrea S; Bendtzen K; Meroni P L; Kim J J; Nicoletti F
Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats.
British journal of pharmacology 2008;155(5):722-30.
2008: Di Paola Rosanna; Cuzzocrea Salvatore
Predictivity and sensitivity of animal models of arthritis.
Autoimmunity reviews 2008;8(1):73-5.
2008: Cuzzocrea Salvatore; Di Paola Rosanna; Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Crisafulli Concetta; Bramanti Placido; Salvemini Daniela
Anti-inflammatory and anti-apoptotic effects of fumonisin B1, an inhibitor of ceramide synthase, in a rodent model of splanchnic ischemia and reperfusion injury.
The Journal of pharmacology and experimental therapeutics 2008;327(1):45-57.
2008: Ndengele Michael M; Cuzzocrea Salvatore; Esposito Emanuela; Mazzon Emanuela; Di Paola Rosanna; Matuschak George M; Salvemini Daniela
Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3154-64.
2008: Esposito Emanuela; Mazzon Emanuela; Riccardi Luisa; Caminiti Rocco; Meli Rosaria; Cuzzocrea Salvatore
Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis.
Journal of pineal research 2008;45(2):166-73.
2008: Esposito Emanuela; Genovese Tiziana; Caminiti Rocco; Bramanti Placido; Meli Rosaria; Cuzzocrea Salvatore
Melatonin regulates matrix metalloproteinases after traumatic experimental spinal cord injury.
Journal of pineal research 2008;45(2):149-56.
2008: Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Di Paola Rosanna; Caminiti Rocco; Meli Rosaria; Bramanti Placido; Cuzzocrea Salvatore
Effect of thalidomide on signal transduction pathways and secondary damage in experimental spinal cord trauma.
Shock (Augusta, Ga.) 2008;30(3):231-40.
2008: Genovese Tiziana; Esposito Emanuela; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Meli Rosaria; Bramanti Placido; Cuzzocrea Salvatore
Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury.
Shock (Augusta, Ga.) 2008;30(2):142-52.
2008: Cuzzocrea Salvatore; Masini Emanuela
Plant histaminase as an investigational drug in splanchnic artery occlusion and reperfusion.
Expert opinion on investigational drugs 2008;17(8):1151-60.
2008: Menegazzi Marta; Di Paola Rosanna; Mazzon Emanuela; Genovese Tiziana; Crisafulli Concetta; Dal Bosco Martina; Zou Zhenzhen; Suzuki Hisanori; Cuzzocrea Salvatore
Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice.
Pharmacological research : the official journal of the Italian Pharmacological Society 2008;58(1):22-31.
2008: Mazzon E; Esposito E; Di Paola R; Muià C; Crisafulli C; Genovese T; Caminiti R; Meli R; Bramanti P; Cuzzocrea S
Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept.
Clinical and experimental immunology 2008;153(1):136-49.
2008: Genovese Tiziana; Esposito Emanuela; Mazzon Emanuela; Di Paola Rosanna; Meli Rosaria; Bramanti Placido; Piomelli Daniele; Calignano Antonio; Cuzzocrea Salvatore
Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury.
The Journal of pharmacology and experimental therapeutics 2008;326(1):12-23.
2008: Tentori Lucio; Muzi Alessia; Dorio Annalisa Susanna; Bultrini Stefano; Mazzon Emanuela; Lacal Pedro M; Shah Girish M; Zhang Jie; Navarra Pierluigi; Nocentini Giuseppe; Cuzzocrea Salvatore; Graziani Grazia
Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity.
European journal of cancer (Oxford, England : 1990) 2008;44(9):1302-14.
2008: Nocentini Giuseppe; Cuzzocrea Salvatore; Genovese Tiziana; Bianchini Rodolfo; Mazzon Emanuela; Ronchetti Simona; Esposito Emanuela; Rosanna Di Paola; Bramanti Placido; Riccardi Carlo
Glucocorticoid-induced tumor necrosis factor receptor-related (GITR)-Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury.
Molecular pharmacology 2008;73(6):1610-21.
2008: Mazzon Emanuela; Cuzzocrea Salvatore
Role of TNF-alpha in ileum tight junction alteration in mouse model of restraint stress.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(5):G1268-80.
2008: Malleo Giuseppe; Mazzon Emanuela; Genovese Tiziana; Di Paola Rosanna; Muià Carmelo; Caminiti Rocco; Esposito Emanuela; Di Bella Paolo; Cuzzocrea Salvatore
Etanercept reduces acute tissue injury and mortality associated to zymosan-induced multiple organ dysfunction syndrome.
Shock (Augusta, Ga.) 2008;29(5):560-71.
2008: Fries Walter; Muja Carmelo; Crisafulli Carmela; Cuzzocrea Salvatore; Mazzon Emanuela
Dynamics of enterocyte tight junctions: effect of experimental colitis and two different anti-TNF strategies.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(4):G938-47.
2008: Genovese Tiziana; Esposito Emanuela; Mazzon Emanuela; Muià Carmelo; Di Paola Rosanna; Meli Rosaria; Bramanti Placido; Cuzzocrea Salvatore
Evidence for the role of mitogen-activated protein kinase signaling pathways in the development of spinal cord injury.
The Journal of pharmacology and experimental therapeutics 2008;325(1):100-14.
2008: Cuzzocrea Salvatore; Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Peli Angelo; Bramanti Placido; Chaudry Irshad H
Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma.
Shock (Augusta, Ga.) 2008;29(3):362-71.
2008: Mariotto Sofia; Esposito Emanuela; Di Paola Rosanna; Ciampa Anna; Mazzon Emanuela; de Prati Alessandra Carcereri; Darra Elena; Vincenzi Simone; Cucinotta Giovanni; Caminiti Rocco; Suzuki Hisanori; Cuzzocrea Salvatore
Protective effect of Arbutus unedo aqueous extract in carrageenan-induced lung inflammation in mice.
Pharmacological research : the official journal of the Italian Pharmacological Society 2008;57(2):110-24.
2008: Murch Oliver; Abdelrahman Maha; Collino Massimo; Gallicchio Margherita; Benetti Elisa; Mazzon Emanuela; Fantozzi Roberto; Cuzzocrea Salvatore; Thiemermann Christoph
Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat.
Critical care medicine 2008;36(2):550-9.
2008: Malleo Giuseppe; Mazzon Emanuela; Genovese Tiziana; Di Paola Rosanna; Caminiti Rocco; Esposito Emanuela; Bramanti Placido; Cuzzocrea Salvatore
Absence of endogenous interleukin-10 enhanced organ dysfunction and mortality associated to zymosan-induced multiple organ dysfunction syndrome.
Cytokine 2008;41(2):136-43.
2008: Genovese T; Rossi A; Mazzon E; Di Paola R; Muià C; Caminiti R; Bramanti P; Sautebin L; Cuzzocrea S
Effects of zileuton and montelukast in mouse experimental spinal cord injury.
British journal of pharmacology 2008;153(3):568-82.
2008: Masini Emanuela; Giannini Lucia; Nistri Silvia; Cinci Lorenzo; Mastroianni Rosanna; Xu Wei; Comhair Suzy A A; Li Dechun; Cuzzocrea Salvatore; Matuschak George M; Salvemini Daniela
Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation.
The Journal of pharmacology and experimental therapeutics 2008;324(2):548-57.
2008: Cuzzocrea Salvatore; Bruscoli Stefano; Mazzon Emanuela; Crisafulli Concetta; Donato Valerio; Di Paola Rosanna; Velardi Enrico; Esposito Emanuela; Nocentini Giuseppe; Riccardi Carlo
Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids.
Molecular pharmacology 2008;73(2):323-37.
2008: Malleo Giuseppe; Mazzon Emanuela; Genovese Tiziana; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Siriwardena Ajith K; Cuzzocrea Salvatore
Effects of thalidomide in a mouse model of cerulein-induced acute pancreatitis.
Shock (Augusta, Ga.) 2008;29(1):89-97.
2008: Esposito Emanuela; Iacono Anna; Muià Carmelo; Crisafulli Concetta; Mattace Raso Giuseppina; Bramanti Placido; Meli Rosaria; Cuzzocrea Salvatore
Signal transduction pathways involved in protective effects of melatonin in C6 glioma cells.
Journal of pineal research 2008;44(1):78-87.
2008: Genovese Tiziana; Mazzon Emanuela; Crisafulli Concetta; Di Paola Rosanna; Muià Carmelo; Esposito Emanuela; Bramanti Placido; Cuzzocrea Salvatore
TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome.
Shock (Augusta, Ga.) 2008;29(1):32-41.
2008: Fries Walter; Muja Carmelo; Crisafulli Carmela; Costantino Giuseppe; Longo Giuseppe; Cuzzocrea Salvatore; Mazzon Emanuela
Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis.
International journal of medical sciences 2008;5(4):169-80.
2008: Genovese T; Cuzzocrea S
Role of free radicals and poly(ADP-ribose)polymerase-1 in the development of spinal cord injury: new potential therapeutic targets.
Current medicinal chemistry 2008;15(5):477-87.
2007: Cuzzocrea Salvatore; Malleo Giuseppe; Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Abdelrahman Maha; Di Paola Rosanna; Thiemermann Cristoph
Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice.
Critical care medicine 2007;35(12):2811-21.
2007: Galle Pia; Jensen Lene; Andersson Christina; Cuzzocrea Salvatore; Di Paola Rosanna; Nicoletti Ferdinando; Svenson Morten; Bendtzen Klaus; Thomsen Allan R; Hansen Morten B
Vaccination with IL-6 analogues induces autoantibodies to IL-6 and influences experimentally induced inflammation.
International immunopharmacology 2007;7(13):1704-13.
2007: Esposito Emanuela; Cuzzocrea Salvatore
The role of nitric oxide synthases in lung inflammation.
Current opinion in investigational drugs (London, England : 2000) 2007;8(11):899-909.
2007: Muscoli Carolina; Cuzzocrea Salvatore; Ndengele Michael M; Mollace Vincenzo; Porreca Frank; Fabrizi Francesca; Esposito Emanuela; Masini Emanuela; Matuschak George M; Salvemini Daniela
Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice.
The Journal of clinical investigation 2007;117(11):3530-9.
2007: El-Sokkary Gamal H; Cuzzocrea Salvatore; Reiter Russel J
Effect of chronic nicotine administration on the rat lung and liver: beneficial role of melatonin.
Toxicology 2007;239(1-2):60-7.
2007: Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Di Paola Rosanna; Bramanti Placido; Cuzzocrea Salvatore
Beneficial effects of FeTSPP, a peroxynitrite decomposition catalyst, in a mouse model of spinal cord injury.
Free radical biology & medicine 2007;43(5):763-80.
2007: Genovese Tiziana; Mazzon Emanuela; Crisafulli Concetta; Esposito Emanuela; Di Paola Rosanna; Muià Carmelo; Di Bella Paolo; Bramanti Placido; Cuzzocrea Salvatore
Effects of combination of melatonin and dexamethasone on secondary injury in an experimental mice model of spinal cord trauma.
Journal of pineal research 2007;43(2):140-53.
2007: D'Agostino Giuseppe; La Rana Giovanna; Russo Roberto; Sasso Oscar; Iacono Anna; Esposito Emanuela; Raso Giuseppina Mattace; Cuzzocrea Salvatore; Lo Verme Jesse; Piomelli Daniele; Meli Rosaria; Calignano Antonio
Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice.
The Journal of pharmacology and experimental therapeutics 2007;322(3):1137-43.
2007: Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Di Paola Rosanna; Di Bella Paolo; Bramanti Placido; Cuzzocrea Salvatore
Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice.
Neuroscience letters 2007;423(1):41-6.
2007: Marzocco Stefania; Piccinelli Anna Lisa; Rastrelli Luca; Mazzon Emanuela; Cuzzocrea Salvatore; Autore Giuseppina
Inhibition of inducible nitric oxide synthase in vitro and in vivo by a water-soluble extract of Wendita calysina leaves.
Naunyn-Schmiedeberg's archives of pharmacology 2007;375(6):349-58.
2007: Malleo Giuseppe; Mazzon Emanuela; Siriwardena Ajith K; Cuzzocrea Salvatore
Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence.
Shock (Augusta, Ga.) 2007;28(2):130-40.
2007: Mazzon Emanuela; Cuzzocrea Salvatore
Absence of functional peroxisome proliferator-activated receptor-alpha enhanced ileum permeability during experimental colitis.
Shock (Augusta, Ga.) 2007;28(2):192-201.
2007: Cuzzocrea S; Genovese T; Mazzon E; Esposito E; Muià C; Abdelrahman M; Di Paola R; Bramanti P; Thiemermann C
Glycogen synthase kinase-3beta inhibition attenuates the development of bleomycin-induced lung injury.
International journal of immunopathology and pharmacology 2007;20(3):619-30.
2007: Nocentini Giuseppe; Cuzzocrea Salvatore; Bianchini Rodolfo; Mazzon Emanuela; Riccardi Carlo
Modulation of acute and chronic inflammation of the lung by GITR and its ligand.
Annals of the New York Academy of Sciences 2007;1107():380-91.
2007: Roviezzo F; Cuzzocrea S; Di Lorenzo A; Brancaleone V; Mazzon E; Di Paola R; Bucci M; Cirino G
Protective role of PI3-kinase-Akt-eNOS signalling pathway in intestinal injury associated with splanchnic artery occlusion shock.
British journal of pharmacology 2007;151(3):377-83.
2007: Stojanovic Ivana; Cuzzocrea Salvatore; Mangano Katia; Mazzon Emanuela; Miljkovic Djordje; Wang Mingjun; Donia Marco; Al Abed Yousef; Kim Joseph; Nicoletti Ferdinando; Stosic-Grujicic Stanislava; Claesson Mogens
In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models.
Clinical immunology (Orlando, Fla.) 2007;123(3):311-23.
2007: Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Di Paola Rosanna; Crisafulli Concetta; Bramanti Placido; Cuzzocrea Salvatore
Inhibition of tyrosine kinase-mediated cellular signalling by Tyrphostins AG126 and AG556 modulates secondary damage in experimental spinal cord trauma.
Neuropharmacology 2007;52(7):1454-71.
2007: Malleo Giuseppe; Mazzon Emanuela; Genovese Tiziana; Di Paola Rosanna; Muià Carmelo; Centorrino Tommaso; Siriwardena Ajith K; Cuzzocrea Salvatore
Etanercept attenuates the development of cerulein-induced acute pancreatitis in mice: a comparison with TNF-alpha genetic deletion.
Shock (Augusta, Ga.) 2007;27(5):542-51.
2007: Nocentini Giuseppe; Ronchetti Simona; Cuzzocrea Salvatore; Riccardi Carlo
GITR/GITRL: more than an effector T cell co-stimulatory system.
European journal of immunology 2007;37(5):1165-9.
2007: Di Paola Rosanna; Cuzzocrea Salvatore
Peroxisome proliferator-activated receptors ligands and ischemia-reperfusion injury.
Naunyn-Schmiedeberg's archives of pharmacology 2007;375(3):157-75.
2007: Cuzzocrea Salvatore; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Abdelrahman Maha; Di Paola Rosanna; Crisafulli Concetta; Bramanti Placido; Thiemermann Christoph
Glycogen synthase kinase-3beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut.
Intensive care medicine 2007;33(5):880-93.
2007: Patel Nimesh S A; Cuzzocrea Salvatore; Collino Massimo; Chaterjee Prabal K; Mazzon Emanuela; Britti Domenico; Yaqoob Muhammad M; Thiemermann Christoph
The role of cycloxygenase-2 in the rodent kidney following ischaemia/reperfusion injury in vivo.
European journal of pharmacology 2007;562(1-2):148-54.
2007: Cuzzocrea Salvatore; Genovese Tiziana; Failla Marco; Vecchio Graziella; Fruciano Mary; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; La Rosa Cristina; Crimi Nunzio; Rizzarelli Enrico; Vancheri Carlo
Protective effect of orally administered carnosine on bleomycin-induced lung injury.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1095-104.
2007: Conti Alfredo; Miscusi Massimo; Cardali Salvatore; Germanò Antonino; Suzuki Hisanori; Cuzzocrea Salvatore; Tomasello Francesco
Nitric oxide in the injured spinal cord: synthases cross-talk, oxidative stress and inflammation.
Brain research reviews 2007;54(1):205-18.
2007: Masini Emanuela; Cuzzocrea Salvatore; Bani Daniele; Mazzon Emanuela; Muja Carmelo; Mastroianni Rosanna; Fabrizi Francesca; Pietrangeli Paola; Marcocci Lucia; Mondovì Bruno; Mannaioni Pier Francesco; Federico Rodolfo
Beneficial effects of a plant histaminase in a rat model of splanchnic artery occlusion and reperfusion.
Shock (Augusta, Ga.) 2007;27(4):409-15.
2007: Esposito Emanuela; Mazzon Emanuela; Muià Carmelo; Meli Rosaria; Sessa Edoardo; Cuzzocrea Salvatore
Splanchnic ischemia and reperfusion injury is reduced by genetic or pharmacological inhibition of TNF-alpha.
Journal of leukocyte biology 2007;81(4):1032-43.
2007: Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Di Paola Rosanna; Crisafulli Concetta; Bramanti Placido; Cuzzocrea Salvatore
N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone reduces severity of experimental spinal cord injury.
Shock (Augusta, Ga.) 2007;27(3):258-65.
2007: Di Paola Rosanna; Mazzon Emanuela; Muià Carmelo; Terrana Dino; Greco Salvatore; Britti Domenico; Santori Domenico; Oteri Giacomo; Cordasco Giancarlo; Cuzzocrea Salvatore
5-Aminoisoquinolin-1(2H)-one, a water-soluble poly (ADP-ribose) polymerase (PARP) inhibitor reduces the evolution of experimental periodontitis in rats.
Journal of clinical periodontology 2007;34(2):95-102.
2007: Tripatara Pinpat; Patel Nimesh S A; Webb Andrew; Rathod Krishnaraj; Lecomte Florence M J; Mazzon Emanuela; Cuzzocrea Salvatore; Yaqoob Mohammed M; Ahluwalia Amrita; Thiemermann Christoph
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase.
Journal of the American Society of Nephrology : JASN 2007;18(2):570-80.
2007: Cuzzocrea S; Salvemini D
Molecular mechanisms involved in the reciprocal regulation of cyclooxygenase and nitric oxide synthase enzymes.
Kidney international 2007;71(4):290-7.
2007: Di Paola R; Mazzon E; Muià C; Crisafulli C; Terrana D; Greco S; Britti D; Santori D; Oteri G; Cordasco G; Cuzzocrea S
Effects of etanercept, a tumour necrosis factor-alpha antagonist, in an experimental model of periodontitis in rats.
British journal of pharmacology 2007;150(3):286-97.
2007: Di Paola Rosanna; Mazzon Emanuela; Muià Carmelo; Crisafulli Concetta; Genovese Tiziana; Di Bella Paolo; Esposito Emanuela; Menegazzi Marta; Meli Rosaria; Suzuki Hisanori; Cuzzocrea Salvatore
Protective effect of Hypericum perforatum in zymosan-induced multiple organ dysfunction syndrome: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2007;16(1):118-30.
2007: Cuzzocrea Salvatore; Di Paola Rosanna; Mazzon Emanuela; Crisafulli Concetta; Genovese Tiziana; Muià Carmelo; Abdelrahman Maha; Esposito Emanuela; Thiemermann Christoph
Glycogen synthase kinase 3beta inhibition reduces the development of nonseptic shock induced by zymosan in mice.
Shock (Augusta, Ga.) 2007;27(1):97-107.
2007: Cuzzocrea Salvatore; Mazzon Emanuela; Genovese Tiziana; Crisafulli Concetta; Min Woo-Kee; Di Paola Rosanna; Muià Carmelo; Li Jia-He; Malleo Giuseppe; Xu Weizhen; Massuda Edmond; Esposito Emanuela; Zhang Jie; Wang Zhao-Qi
Role of poly(ADP-ribose) glycohydrolase in the development of inflammatory bowel disease in mice.
Free radical biology & medicine 2007;42(1):90-105.
2007: Cuzzocrea Salvatore; Ronchetti Simona; Genovese Tiziana; Mazzon Emanuela; Agostini Massimiliano; Di Paola Rosanna; Esposito Emanuela; Muià Carmelo; Nocentini Giuseppe; Riccardi Carlo
Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(1):117-29.
2007: Cuzzocrea Salvatore; Bruscoli Stefano; Crisafulli Concetta; Mazzon Emanuela; Agostini Massimiliano; Muià Carmelo; Esposito Emanuela; Di Virgilio Rosa; Meli Rosaria; Vegeto Elisabetta; Maggi Adriana; Riccardi Carlo
Estrogen receptor antagonist fulvestrant (ICI 182,780) inhibits the anti-inflammatory effect of glucocorticoids.
Molecular pharmacology 2007;71(1):132-44.
2007: Mazzon Emanuela; Cuzzocrea Salvatore
Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation.
Respiratory research 2007;8():75.
2007: Paola Rosanna Di; Cuzzocrea Salvatore
Peroxisome proliferator-activated receptors and acute lung injury.
PPAR research 2007;2007():63745.
2007: Malleo Giuseppe; Mazzon Emanuela; Siriwardena Ajith K; Cuzzocrea Salvatore
TNF-alpha as a therapeutic target in acute pancreatitis--lessons from experimental models.
TheScientificWorldJournal 2007;7():431-48.
2007: Rossi Antonietta; Pergola Carlo; Cuzzocrea Salvatore; Sautebin Lidia
The role of 5-lipoxygenase and leukotrienes in shock and ischemia-reperfusion injury.
TheScientificWorldJournal 2007;7():56-74.
2006: De Luca Grazia; Di Giorgio Rosa Maria; Macaione Salvatore; Calpona Pina Rita; Di Paola Eugenio Donato; Costa Nicola; Cuzzocrea Salvatore; Citraro Rita; Russo Emilio; De Sarro Giovambattista
Amino acid levels in some brain areas of inducible nitric oxide synthase knock out mouse (iNOS-/-) before and after pentylenetetrazole kindling.
Pharmacology, biochemistry, and behavior 2006;85(4):804-12.
2006: Di Paola Rosanna; Esposito Emanuela; Mazzon Emanuela; Genovese Tiziana; Muià Carmelo; Crisafulli Concetta; Malleo Giuseppe; Sessa Edoardo; Meli Rosaria; Cuzzocrea Salvatore
Absence of peroxisome proliferators-activated receptors (PPAR)alpha enhanced the multiple organ failure induced by zymosan.
Shock (Augusta, Ga.) 2006;26(5):477-84.
2006: Cuzzocrea S; Crisafulli C; Mazzon E; Esposito E; Muià C; Abdelrahman M; Di Paola R; Thiemermann C
Inhibition of glycogen synthase kinase-3beta attenuates the development of carrageenan-induced lung injury in mice.
British journal of pharmacology 2006;149(6):687-702.
2006: Mazzon Emanuela; Esposito Emanuela; Crisafulli Concetta; Riccardi Luisa; Muià Carmelo; Di Bella Paolo; Meli Rosaria; Cuzzocrea Salvatore
Melatonin modulates signal transduction pathways and apoptosis in experimental colitis.
Journal of pineal research 2006;41(4):363-73.
2006: Mazzon Emanuela; Genovese Tiziana; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Malleo Giuseppe; Esposito Emanuela; Meli Rosaria; Sessa Edoardo; Cuzzocrea Salvatore
Effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, in a mouse model of acute pancreatitis induced by cerulein.
European journal of pharmacology 2006;549(1-3):149-56.
2006: Imperatore Francesco; Cuzzocrea Salvatore; De Lucia Domenico; Sessa Marcella; Rinaldi Barbara; Capuano Annalisa; Liguori Giovanni; Filippelli Amelia; Rossi Francesco
Hyperbaric oxygen therapy prevents coagulation disorders in an experimental model of multiple organ failure syndrome.
Intensive care medicine 2006;32(11):1881-8.
2006: Di Paola Rosanna; Mazzon Emanuela; Muià Carmelo; Crisafulli Concetta; Genovese Tiziana; Di Bella Paolo; Esposito Emanuela; Menegazzi Marta; Meli Rosaria; Suzuki Hisanori; Cuzzocrea Salvatore
Green tea polyphenol extract attenuates zymosan-induced non-septic shock in mice.
Shock (Augusta, Ga.) 2006;26(4):402-9.
2006: Crisafulli Concetta; Mazzon Emanuela; Muià Carmelo; Bella PaoloDi; Esposito Emanuela; Meli Rosaria; Cuzzocrea Salvatore
Effects of combination of melatonin and dexamethasone on acute lung injury in a mice model of carrageenan-induced pleurisy.
Journal of pineal research 2006;41(3):228-37.
2006: Cuzzocrea Salvatore; Genovese Tiziana; Mazzon Emanuela; Crisafulli Concetta; Min Wookee; Di Paola Rosanna; Muià Carmelo; Li Jia-He; Esposito Emanuela; Bramanti Placido; Xu Weizheng; Massuda Edmond; Zhang Jie; Wang Zhao-Qi
Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma.
The Journal of pharmacology and experimental therapeutics 2006;319(1):127-38.
2006: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Esposito Emanuela; Macarthur Heather; Matuschak George M; Salvemini Daniela
A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock.
The Journal of pharmacology and experimental therapeutics 2006;319(1):73-81.
2006: Persichini Tiziana; Percario Zulema; Mazzon Emanuela; Colasanti Marco; Cuzzocrea Salvatore; Musci Giovanni
Copper activates the NF-kappaB pathway in vivo.
Antioxidants & redox signaling 2006;8(9-10):1897-904.
2006: Masini Emanuela; Cuzzocrea Salvatore; Mazzon Emanuela; Muià Carmelo; Vannacci Alfredo; Fabrizi Francesca; Bani Daniele
Protective effects of relaxin in ischemia/reperfusion-induced intestinal injury due to splanchnic artery occlusion.
British journal of pharmacology 2006;148(8):1124-32.
2006: Tentori Lucio; Leonetti Carlo; Scarsella Marco; Muzi Alessia; Mazzon Emanuela; Vergati Matteo; Forini Olindo; Lapidus Rena; Xu Weizheng; Dorio Annalisa Susanna; Zhang Jie; Cuzzocrea Salvatore; Graziani Grazia
Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(10):1709-11.
2006: Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Malleo Giuseppe; Esposito Emanuela; Cuzzocrea Salvatore
Role of peroxisome proliferator-activated receptor-alpha in acute pancreatitis induced by cerulein.
Immunology 2006;118(4):559-70.
2006: Pergola Carlo; Rossi Antonietta; Dugo Paola; Cuzzocrea Salvatore; Sautebin Lidia
Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;15(1):30-9.
2006: Tancevski Ivan; Wehinger Andreas; Schgoer Wilfried; Eller Philipp; Cuzzocrea Salvatore; Foeger Bernhard; Patsch Josef R; Ritsch Andreas
Aspirin regulates expression and function of scavenger receptor-BI in macrophages: studies in primary human macrophages and in mice.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1328-35.
2006: Cuzzocrea Salvatore; Nocentini Giuseppe; Di Paola Rosanna; Agostini Massimiliano; Mazzon Emanuela; Ronchetti Simona; Crisafulli Concetta; Esposito Emanuela; Caputi Achille P; Riccardi Carlo
Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):631-41.
2006: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Dugo Laura; Collin Marika; Britti Domenico; Caputi Achille P; Thiemermann Christoph
Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse.
Clinical immunology (Orlando, Fla.) 2006;120(1):57-67.
2006: Cuzzocrea Salvatore; Genovese Tiziana; Mazzon Emanuela; Crisafulli Concetta; Di Paola Rosanna; Muià Carmelo; Collin Marika; Esposito Emanuela; Bramanti Placido; Thiemermann Christoph
Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma.
The Journal of pharmacology and experimental therapeutics 2006;318(1):79-89.
2006: Genovese Tiziana; Mazzon Emanuela; Menegazzi Marta; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Bramanti Placido; Suzuki Hisanori; Cuzzocrea Salvatore
Neuroprotection and enhanced recovery with hypericum perforatum extract after experimental spinal cord injury in mice.
Shock (Augusta, Ga.) 2006;25(6):608-17.
2006: Muià Carmelo; Mazzon Emanuela; Maiere Daniele; Zito Daniele; Di Paola Rosanna; Domenico Santori; Crisafulli Concetta; Britti Domenico; Cuzzocrea Salvatore
Pyrrolidine dithiocarbamate reduced experimental periodontitis.
European journal of pharmacology 2006;539(3):205-10.
2006: Cuzzocrea Salvatore
Peroxisome proliferator-activated receptors and acute lung injury.
Current opinion in pharmacology 2006;6(3):263-70.
2006: Mazzon Emanuela; Cuzzocrea Salvatore
Thalidomide treatment reduces the alteration of paracellular barrier function in mice ileum during experimental colitis.
Shock (Augusta, Ga.) 2006;25(5):515-21.
2006: Dugo Laura; Abdelrahman Maha; Murch Oliver; Mazzon Emanuela; Cuzzocrea Salvatore; Thiemermann Christoph
Glycogen synthase kinase-3beta inhibitors protect against the organ injury and dysfunction caused by hemorrhage and resuscitation.
Shock (Augusta, Ga.) 2006;25(5):485-91.
2006: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Peli Angelo; Bonato Andrea; Britti Domenico; Genovese Tiziana; Muià Carmelo; Crisafulli Concetta; Caputi Achille P
The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation.
Journal of leukocyte biology 2006;79(5):999-1010.
2006: Mazzon Emanuela; Sautebin Lidia; Caputi Achille P; Cuzzocrea Salvatore
5-lipoxygenase modulates the alteration of paracellular barrier function in mice ileum during experimental colitis.
Shock (Augusta, Ga.) 2006;25(4):377-83.
2006: Bucolo Claudio; Marrazzo Agostino; Ronsisvalle Simone; Ronsisvalle Giuseppe; Cuzzocrea Salvatore; Mazzon Emanuela; Caputi Achille; Drago Filippo
A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors.
European journal of pharmacology 2006;536(1-2):200-3.
2006: Muià Carmelo; Mazzon Emanuela; Zito Daniele; Maiere Daniele; Britti Domenico; Crisafulli Concetta; Oteri Giacomo; Cordasco Giancarlo; Cuzzocrea Salvatore
Cloricromene, a coumarine derivative, reduced the development of periodontitis in rats.
Naunyn-Schmiedeberg's archives of pharmacology 2006;373(1):51-9.
2006: Cuzzocrea Salvatore; Di Paola Rosanna; Mazzon Emanuela; Patel Nimesh S A; Genovese Tiziana; Muià Carmelo; Crisafulli Concetta; Caputi Achille P; Thiemermann Christoph
Erythropoietin reduces the development of nonseptic shock induced by zymosan in mice.
Critical care medicine 2006;34(4):1168-77.
2006: Rivera Dagmar García; Balmaseda Ivones Hernández; León Alina Alvarez; Hernández Belkis Cancio; Montiel Lucía Márquez; Garrido Gabino Garrido; Cuzzocrea Salvatore; Hernández René Delgado
Anti-allergic properties of Mangifera indica L. extract (Vimang) and contribution of its glucosylxanthone mangiferin.
The Journal of pharmacy and pharmacology 2006;58(3):385-92.
2006: Menegazzi Marta; Di Paola Rosanna; Mazzon Emanuela; Muià Carmelo; Genovese Tiziana; Crisafulli Concetta; Suzuki Hisanori; Cuzzocrea Salvatore
Hypericum perforatum attenuates the development of carrageenan-induced lung injury in mice.
Free radical biology & medicine 2006;40(5):740-53.
2006: Genovese Tiziana; Mazzon Emanuela; Crisafulli Concetta; Di Paola Rosanna; Muià Carmelo; Bramanti Placido; Cuzzocrea Salvatore
Immunomodulatory effects of etanercept in an experimental model of spinal cord injury.
The Journal of pharmacology and experimental therapeutics 2006;316(3):1006-16.
2006: Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Menegazzi Marta; Malleo Giuseppe; Suzuki Hisanori; Cuzzocrea Salvatore
Hypericum perforatum attenuates the development of cerulein-induced acute pancreatitis in mice.
Shock (Augusta, Ga.) 2006;25(2):161-7.
2006: Genovese Tiziana; Mazzon Emanuela; Mariotto Sofia; Menegazzi Marta; Cardali Salvatore; Conti Alfredo; Suzuki Hisanori; Bramanti Placido; Cuzzocrea Salvatore
Modulation of nitric oxide homeostasis in a mouse model of spinal cord injury.
Journal of neurosurgery. Spine 2006;4(2):145-53.
2006: Marzocco Stefania; Mazzon Emanuela; Pinto Aldo; Autore Giuseppina; Cuzzocrea Salvatore
Tyrphostin AG 126 reduces intestinal ischemia-reperfusion injury in the rat.
Naunyn-Schmiedeberg's archives of pharmacology 2006;372(5):362-73.
2006: Di Paola R; Mazzon E; Maiere D; Zito D; Britti D; De Majo M; Genovese T; Cuzzocrea S
Rosiglitazone reduces the evolution of experimental periodontitis in the rat.
Journal of dental research 2006;85(2):156-61.
2006: Cannarile Lorenza; Fallarino Francesca; Agostini Massimiliano; Cuzzocrea Salvatore; Mazzon Emanuela; Vacca Carmine; Genovese Tiziana; Migliorati Graziella; Ayroldi Emira; Riccardi Carlo
Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines.
Blood 2006;107(3):1039-47.
2006: Muià Carmelo; Mazzon Emanuela; Crisafulli Concetta; Di Paola Rosanna; Genovese Tiziana; Caputi Achille P; Cuzzocrea Salvatore
ROLE of endogenous peroxisome proliferator-activated receptor-alpha (PPAR-alpha) ligands in the development of gut ischemia and reperfusion in mice.
Shock (Augusta, Ga.) 2006;25(1):17-22.
2006: Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Crisafulli Concetta; Muià Carmelo; Bramanti Placido; Cuzzocrea Salvatore
Increased oxidative-related mechanisms in the spinal cord injury in old rats.
Neuroscience letters 2006;393(2-3):141-6.
2006: Esposito Emanuela; Cuzzocrea Salvatore; Meli Rosaria
Peroxisome proliferator-activated receptors and shock state.
TheScientificWorldJournal 2006;6():1770-82.
2006: Failla Marco; Genovese Tiziana; Mazzon Emanuela; Gili Elisa; Muià Carmelo; Sortino Mariangela; Crimi Nunzio; Caputi Achille P; Cuzzocrea Salvatore; Vancheri Carlo
Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury.
Respiratory research 2006;7():137.
2006: Cuzzocrea Salvatore
Role of nitric oxide and reactive oxygen species in arthritis.
Current pharmaceutical design 2006;12(27):3551-70.
2006: Mirshafiey A; Saadat F; Attar M; Di Paola R; Sedaghat R; Cuzzocrea S
Design of a new line in treatment of experimental rheumatoid arthritis by artesunate.
Immunopharmacology and immunotoxicology 2006;28(3):397-410.
2006: Di Filippo Clara; Cuzzocrea Salvatore; Rossi Francesco; Marfella Raffaele; D'Amico Michele
Oxidative stress as the leading cause of acute myocardial infarction in diabetics.
Cardiovascular drug reviews 2006;24(2):77-87.
2005: Cuzzocrea Salvatore; Mazzon Emanuela; di Paola Rosanna; Genovese Tiziana; Muià Carmelo; Caputi Achille P; Salvemini Daniela
Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance.
Arthritis and rheumatism 2005;52(12):3755-60.
2005: Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Caputi Achille P; Cuzzocrea Salvatore
ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR alpha IN THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY.
Shock (Augusta, Ga.) 2005;24(6):547-55.
2005: Di Paola Rosanna; Mazzon Emanuela; Xu Weizheng; Genovese Tiziana; Ferrraris Dana; Muià Carmelo; Crisafulli Concetta; Zhang Jie; Cuzzocrea Salvatore
Treatment with PARP-1 inhibitors, GPI 15427 or GPI 16539, ameliorates intestinal damage in rat models of colitis and shock.
European journal of pharmacology 2005;527(1-3):163-71.
2005: Morello Silvana; Vellecco Valentina; Roviezzo Fiorentina; Maffia Pasquale; Cuzzocrea Salvatore; Cirino Giuseppe; Cicala Carla
A protective role for proteinase activated receptor 2 in airways of lipopolysaccharide-treated rats.
Biochemical pharmacology 2005;71(1-2):223-30.
2005: Balachandra Srinivasan; Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Thiemerman Christoph; Siriwardena Ajith K; Cuzzocrea Salvatore
Inhibition of tyrosine-kinase-mediated cellular signaling by tyrphostins AG 126 and AG556 modulates murine experimental acute pancreatitis.
Surgery 2005;138(5):913-23.
2005: Di Paola Rosanna; Mazzon Emanuela; Zito Daniele; Maiere Daniele; Britti Domenico; Genovese Tiziana; Cuzzocrea Salvatore
Effects of Tempol, a membrane-permeable radical scavenger, in a rodent model periodontitis.
Journal of clinical periodontology 2005;32(10):1062-8.
2005: Rossi Antonietta; Acquaviva Angela Maria; Iuliano Francesca; Di Paola Rosanna; Cuzzocrea Salvatore; Sautebin Lidia
Up-regulation of prostaglandin biosynthesis by leukotriene C4 in elicited mice peritoneal macrophages activated with lipopolysaccharide/interferon-{gamma}.
Journal of leukocyte biology 2005;78(4):985-91.
2005: De Paola Rosanna; Muià Carmelo; Mazzon Emanuela; Genovese Tiziana; Crisafulli Concetta; Menegazzi Marta; Caputi Achille P; Suzuki Hisanori; Cuzzocrea Salvatore
Effects of Hypericum perforatum extract in a rat model of ischemia and reperfusion injury.
Shock (Augusta, Ga.) 2005;24(3):255-63.
2005: Genovese Tiziana; Di Paola Rosanna; Mazzon Emanuela; Muià Carmelo; Caputi Achille P; Cuzzocrea Salvatore
Melatonin limits lung injury in bleomycin treated mice.
Journal of pineal research 2005;39(2):105-12.
2005: Mazzon Emanuela; Muià Carmelo; Paola Rosanna Di; Genovese Tiziana; Menegazzi Marta; De Sarro Angelina; Suzuki Hisanori; Cuzzocrea Salvatore
Green tea polyphenol extract attenuates colon injury induced by experimental colitis.
Free radical research 2005;39(9):1017-25.
2005: Muth Claus-Martin; Radermacher Peter; Cuzzocrea Salvatore
Hyperbaric oxygen and sepsis: time to recognize.
Intensive care medicine 2005;31(9):1150-2.
2005: Genovese Tiziana; Mazzon Emanuela; Rossi Antonietta; Di Paola Rosanna; Cannavò Giuseppe; Muià Carmelo; Crisafulli Concetta; Bramanti Placido; Sautebin Lidia; Cuzzocrea Salvatore
Involvement of 5-lipoxygenase in spinal cord injury.
Journal of neuroimmunology 2005;166(1-2):55-64.
2005: Cuzzocrea Salvatore; Ayroldi Emira; Di Paola Rosanna; Agostini Massimiliano; Mazzon Emanuela; Bruscoli Stefano; Genovese Tiziana; Ronchetti Simona; Caputi Achille P; Riccardi Carlo
Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1253-65.
2005: Mirshafiey Abbas; Cuzzocrea Salvatore; Rehm Bernd H A; Matsuo Hidenori
M2000: a revolution in pharmacology.
Medical science monitor : international medical journal of experimental and clinical research 2005;11(8):PI53-63.
2005: Saadat Farshid; Cuzzocrea Salvatore; Di Paola Rosanna; Pezeshki Mohammad; Khorramizadeh Mohammad Reza; Sedaghat Mohammad; Razavi Alireza; Mirshafiey Abbas
Effect of pyrimethamine in experimental rheumatoid arthritis.
Medical science monitor : international medical journal of experimental and clinical research 2005;11(8):BR293-9.
2005: Cuzzocrea Salvatore; Wang Zhao-Qi
Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;52(1):100-8.
2005: Cuzzocrea Salvatore
Shock, inflammation and PARP.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;52(1):72-82.
2005: Ottanà Rosaria; Maccari Rosanna; Barreca Maria Letizia; Bruno Giuseppe; Rotondo Archimede; Rossi Antonietta; Chiricosta Giuseppa; Di Paola Rosanna; Sautebin Lidia; Cuzzocrea Salvatore; Vigorita Maria Gabriella
5-Arylidene-2-imino-4-thiazolidinones: design and synthesis of novel anti-inflammatory agents.
Bioorganic & medicinal chemistry 2005;13(13):4243-52.
2005: Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Cannavò Giuseppe; Muià Carmelo; Bramanti Placido; Cuzzocrea Salvatore
Role of endogenous ligands for the peroxisome proliferators activated receptors alpha in the secondary damage in experimental spinal cord trauma.
Experimental neurology 2005;194(1):267-78.
2005: Cuzzocrea Salvatore; Mazzon Emanuela; Paola Rosanna Di; Genovese Tiziana; Muià Carmelo; Caputi Achille P; Salvemini Daniela
Effects of combination M40403 and dexamethasone therapy on joint disease in a rat model of collagen-induced arthritis.
Arthritis and rheumatism 2005;52(6):1929-40.
2005: Di Paola Rosanna; Mazzon Emanuela; Rotondo Federico; Dattola Francesco; Britti Domenico; De Majo Massimo; Genovese Tiziana; Cuzzocrea Salvatore
Reduced development of experimental periodontitis by treatment with M40403, a superoxide dismutase mimetic.
European journal of pharmacology 2005;516(2):151-7.
2005: Mollace Vincenzo; Muscoli Carolina; Masini Emanuela; Cuzzocrea Salvatore; Salvemini Daniela
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors.
Pharmacological reviews 2005;57(2):217-52.
2005: Mazzon Emanuela; Muià Carmelo; Di Paola Rosanna; Genovese Tiziana; De Sarro Angelina; Cuzzocrea Salvatore
Thalidomide treatment reduces colon injury induced by experimental colitis.
Shock (Augusta, Ga.) 2005;23(6):556-64.
2005: Corsini Emanuela; Di Paola Rosanna; Viviani Barbara; Genovese Tiziana; Mazzon Emanuela; Lucchi Laura; Marinovich Marina; Galli Corrado Lodovico; Cuzzocrea Salvatore
Increased carrageenan-induced acute lung inflammation in old rats.
Immunology 2005;115(2):253-61.
2005: Cuzzocrea Salvatore; Rossi Antonietta; Mazzon Emanuela; Di Paola Rosanna; Genovese Tiziana; Muià Carmelo; Caputi Achille P; Sautebin Lidia
5-Lipoxygenase modulates colitis through the regulation of adhesion molecule expression and neutrophil migration.
Laboratory investigation; a journal of technical methods and pathology 2005;85(6):808-22.
2005: Muià Carmelo; Mazzon Emanuela; Di Paola Rosanna; Genovese Tiziana; Menegazzi Marta; Caputi Achille P; Suzuki Hisanori; Cuzzocrea Salvatore
Green tea polyphenol extract attenuates ischemia/reperfusion injury of the gut.
Naunyn-Schmiedeberg's archives of pharmacology 2005;371(5):364-74.
2005: Mirshafiey A; Cuzzocrea S; Rehm B; Mazzon E; Saadat F; Sotoude M
Treatment of experimental arthritis with M2000, a novel designed non-steroidal anti-inflammatory drug.
Scandinavian journal of immunology 2005;61(5):435-41.
2005: Marzocco Stefania; Di Paola Rosanna; Mazzon Emanuela; Genovese Tiziana; Britti Domenico; Pinto Aldo; Autore Giuseppina; Cuzzocrea Salvatore
The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock.
Intensive care medicine 2005;31(5):693-700.
2005: Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Threadgill Michael D; Caputi Achille P; Thiemermann Christoph; Cuzzocrea Salvatore
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury.
The Journal of pharmacology and experimental therapeutics 2005;313(2):529-38.
2005: Cuzzocrea Salvatore; Di Paola Rosanna; Mazzon Emanuela; Cortes Ulrich; Genovese Tiziana; Muià Carmelo; Li Weixing; Xu Weizheng; Li Jia-He; Zhang Jie; Wang Zhao-Qi
PARG activity mediates intestinal injury induced by splanchnic artery occlusion and reperfusion.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(6):558-66.
2005: Chatterjee Prabal K; Todorovic Zoran; Sivarajah Ahila; Mota-Filipe Helder; Brown Paul A J; Stewart Keith N; Mazzon Emanuela; Cuzzocrea Salvatore; Thiemermann Christoph
Inhibitors of calpain activation (PD150606 and E-64) and renal ischemia-reperfusion injury.
Biochemical pharmacology 2005;69(7):1121-31.
2005: Genovese Tiziana; Mazzon Emanuela; Muià Carmelo; Bramanti Placido; De Sarro Angelina; Cuzzocrea Salvatore
Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin.
Journal of pineal research 2005;38(3):198-208.
2005: Cuzzocrea Salvatore; Mazzon Emanuela; di Paola Rosanna; Genovese Tiziana; Patel Nimesh S A; Britti Domenico; de Majo Massimo; Caputi Achille P; Thiemermann Christoph
Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse.
Arthritis and rheumatism 2005;52(3):940-50.
2005: Di Filippo Clara; Marfella Raffaele; Cuzzocrea Salvatore; Piegari Elena; Petronella Pasquale; Giugliano Dario; Rossi Francesco; D'Amico Michele
Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion.
Diabetes 2005;54(3):803-10.
2005: Scott Gwen S; Cuzzocrea Salvatore; Genovese Tiziana; Koprowski Hilary; Hooper D Craig
Uric acid protects against secondary damage after spinal cord injury.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3483-8.
2005: Patel Nimesh S A; Cortes Ulrich; Di Poala Rosanna; Mazzon Emanuela; Mota-Filipe Helder; Cuzzocrea Salvatore; Wang Zhao-Qi; Thiemermann Christoph
Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury.
Journal of the American Society of Nephrology : JASN 2005;16(3):712-9.
2005: Patel Nimesh S A; Chatterjee Prabal K; Di Paola Rosanna; Mazzon Emanuela; Britti Domenico; De Sarro Angelina; Cuzzocrea Salvatore; Thiemermann Christoph
Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion.
The Journal of pharmacology and experimental therapeutics 2005;312(3):1170-8.
2005: Genovese T; Cuzzocrea S; Di Paola R; Mazzon E; Mastruzzo C; Catalano P; Sortino M; Crimi N; Caputi A P; Thiemermann C; Vancheri C
Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(2):225-34.
2005: Abdelrahman Maha; Mazzon Emanuela; Bauer Michael; Bauer Inge; Delbosc Sandrine; Cristol Jean-Paul; Patel Nimesh S A; Cuzzocrea Salvatore; Thiemermann Christoph
Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock.
Shock (Augusta, Ga.) 2005;23(2):107-14.
2005: Genovese Tiziana; Mazzon Emanuela; Muià Carmelo; Patel Nimesh S A; Threadgill Michael D; Bramanti Placido; De Sarro Angelina; Thiemermann Christoph; Cuzzocrea Salvatore
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma.
The Journal of pharmacology and experimental therapeutics 2005;312(2):449-57.
2005: Di Paola Rosanna; Mazzon Emanuela; Patel Nimesh S A; Genovese Tiziana; Muià Carmelo; Thiemermann Christoph; De Sarro Angelina; Cuzzocrea Salvatore
Beneficial effects of GW274150 treatment on the development of experimental colitis induced by dinitrobenzene sulfonic acid.
European journal of pharmacology 2005;507(1-3):281-9.
2005: Cuzzocrea Salvatore; Saadat Farshid; Di Paola Rosanna; Mirshafiey Abbas
Artemether: a new therapeutic strategy in experimental rheumatoid arthritis.
Immunopharmacology and immunotoxicology 2005;27(4):615-30.
2005: Di Paola Rosanna; Mazzon Emanuela; Muià Carmelo; Genovese Tiziana; Menegazzi Marta; Zaffini Raffaela; Suzuki Hisanory; Cuzzocrea Salvatore
Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice.
Respiratory research 2005;6():66.
2005: Genovese Tiziana; Cuzzocrea Salvatore; Di Paola Rosanna; Failla Marco; Mazzon Emanuela; Sortino Maria Angela; Frasca Giuseppina; Gili Elisa; Crimi Nunzio; Caputi Achille P; Vancheri Carlo
Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury.
Respiratory research 2005;6():58.
2004: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Genovese Tiziana; Patel Nimesh S A; Muià Carmelo; Threadgill Michael D; De Sarro Angelina; Thiemermann Christoph
5-Aminoisoquinolinone reduces colon injury by experimental colitis.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(6):464-73.
2004: Cuzzocrea Salvatore; Di Paola Rosanna; Mazzon Emanuela; Genovese Tiziana; Muià Carmelo; Centorrino Tommaso; Caputi Achille P
Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-alpha) in the development of inflammatory bowel disease in mice.
Laboratory investigation; a journal of technical methods and pathology 2004;84(12):1643-54.
2004: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Patel Nimesh S A; Genovese Tiziana; Muià Carmelo; De Sarro Angelina; Thiemermann Christoph
Erythropoietin reduces the development of experimental inflammatory bowel disease.
The Journal of pharmacology and experimental therapeutics 2004;311(3):1272-80.
2004: Suzuki Ylenia; Masini Emanuela; Mazzocca Cosimo; Cuzzocrea Salvatore; Ciampa Anna; Suzuki Hisanori; Bani Daniele
Inhibition of poly(ADP-ribose) polymerase prevents allergen-induced asthma-like reaction in sensitized Guinea pigs.
The Journal of pharmacology and experimental therapeutics 2004;311(3):1241-8.
2004: Marzocco Stefania; Di Paola Rosanna; Ribecco Maria Teresa; Sorrentino Raffaella; Domenico Britti; Genesio Massimini; Pinto Aldo; Autore Giuseppina; Cuzzocrea Salvatore
Effect of methylguanidine in a model of septic shock induced by LPS.
Free radical research 2004;38(11):1143-53.
2004: Collin Marika; Rossi Antonietta; Cuzzocrea Salvatore; Patel Nimesh S A; Di Paola Rosanna; Hadley Julia; Collino Massimo; Sautebin Lidia; Thiemermann Christoph
Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
Journal of leukocyte biology 2004;76(5):961-70.
2004: Cuzzocrea Salvatore; Nocentini Giuseppe; Di Paola Rosanna; Mazzon Emanuela; Ronchetti Simona; Genovese Tiziana; Muià Carmelo; Caputi Achille P; Riccardi Carlo
Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock.
Journal of leukocyte biology 2004;76(5):933-40.
2004: Chatterjee Prabal K; Todorovic Zoran; Sivarajah Ahila; Mota-Filipe Helder; Brown Paul A J; Stewart Keith N; Cuzzocrea Salvatore; Thiemermann Christoph
Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney.
European journal of pharmacology 2004;503(1-3):173-83.
2004: Pétrilli Virginie; Herceg Zdenko; Hassa Paul O; Patel Nimesh S A; Di Paola Rosanna; Cortes Ulrich; Dugo Laura; Filipe Helder-Mota; Thiemermann Christoph; Hottiger Michael O; Cuzzocrea Salvatore; Wang Zhao-Qi
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice.
The Journal of clinical investigation 2004;114(8):1072-81.
2004: La Rosa Giovanni; Cardali Salvatore; Genovese Tiziana; Conti Alfredo; Di Paola Rosanna; La Torre Domenico; Cacciola Fabio; Cuzzocrea Salvatore
Inhibition of the nuclear factor-kappaB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in rats.
Journal of neurosurgery. Spine 2004;1(3):311-21.
2004: Di Paola Rosanna; Di Marco Roberto; Mazzon Emanuela; Genovese Tiziana; Bendtzen Klaus; Macrì Battesimo; Nicoletti Ferdinando; Cuzzocrea Salvatore
Prevention of carrageenan-induced pleurisy in mice by anti-CD30 ligand monoclonal antibody.
Clinical immunology (Orlando, Fla.) 2004;113(1):64-73.
2004: Cuzzocrea Salvatore; Di Paola Rosanna; Mazzon Emanuela; Genovese Tiziana; Muià Carmelo; Caputi Achille P
WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock.
Shock (Augusta, Ga.) 2004;22(4):340-6.
2004: Cuzzocrea Salvatore; Rossi Antonietta; Serraino Ivana; Di Paola Rosanna; Dugo Laura; Genovese Tiziana; Britti Domenico; Sciarra Giuseppe; De Sarro Angelina; Caputi Achille P; Sautebin Lidia
Role of 5-lipoxygenase in the multiple organ failure induced by zymosan.
Intensive care medicine 2004;30(10):1935-43.
2004: Dugo Laura; Collin Marika; Cuzzocrea Salvatore; Thiemermann Christoph
15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria.
European journal of pharmacology 2004;498(1-3):295-301.
2004: Marfella Raffaele; Esposito Katherine; Nappo Francesco; Siniscalchi Mario; Sasso Ferdinando Carlo; Portoghese Michele; Di Marino Maria Pia; Baldi Alfonso; Cuzzocrea Salvatore; Di Filippo Clara; Barboso Guglielmo; Baldi Feliciano; Rossi Francesco; D'Amico Michele; Giugliano Dario
Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes.
Diabetes 2004;53(9):2383-91.
2004: Patel Nimesh S A; Sharples Edward J; Cuzzocrea Salvatore; Chatterjee Prabal K; Britti Domenico; Yaqoob Muhammad M; Thiemermann Christoph
Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo.
Kidney international 2004;66(3):983-9.
2004: Cuzzocrea Salvatore; Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Britti Domenico; Salvemini Daniela
Reduction in the development of cerulein-induced acute pancreatitis by treatment with M40401, a new selective superoxide dismutase mimetic.
Shock (Augusta, Ga.) 2004;22(3):254-61.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Patel Nimesh S A; Caputi Achille P; Thiemermann Christoph
Tempol reduces the activation of nuclear factor-kappaB in acute inflammation.
Free radical research 2004;38(8):813-9.
2004: Sautebin Lidia; Rossi Antonietta; Serraino Ivana; Dugo Paola; Di Paola Rosanna; Mondello Luigi; Genovese Tiziana; Britti Domenico; Peli Angelo; Dugo Giovanni; Caputi Achille P; Cuzzocrea Salvatore
Effect of anthocyanins contained in a blackberry extract on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.
Planta medica 2004;70(8):745-52.
2004: Di Filippo Clara; Cuzzocrea Salvatore; Marfella Raffaele; Fabbroni Valentina; Scollo Giuseppe; Berrino Liberato; Giugliano Dario; Rossi Francesco; D'Amico Michele
M40403 prevents myocardial injury induced by acute hyperglycaemia in perfused rat heart.
European journal of pharmacology 2004;497(1):65-74.
2004: Patel Nimesh S A; Cuzzocrea Salvatore; Chatterjee Prabal K; Di Paola Rosanna; Sautebin Lidia; Britti Domenico; Thiemermann Christoph
Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
Molecular pharmacology 2004;66(2):220-7.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Ndengele Michael; Salvemini Daniela
Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation.
Antioxidants & redox signaling 2004;6(4):699-704.
2004: Marzocco Stefania; Di Paola Rosanna; Genovese Tiziana; Sorrentino Raffaella; Britti Domenico; Scollo Giuseppe; Pinto Aldo; Cuzzocrea Salvatore; Autore Giuseppina
Methylguanidine reduces the development of non septic shock induced by zymosan in mice.
Life sciences 2004;75(12):1417-33.
2004: Virlos Ioannis; Mazzon Emanuela; Serraino Ivana; Genovese Tiziana; Di Paola Rosanna; Thiemerman Christoph; Siriwardena Ajith; Cuzzocrea Salvatore
Calpain I inhibitor ameliorates the indices of disease severity in a murine model of cerulein-induced acute pancreatitis.
Intensive care medicine 2004;30(8):1645-51.
2004: Cuzzocrea Salvatore
Peroxisome proliferator-activated receptors gamma ligands and ischemia and reperfusion injury.
Vascular pharmacology 2004;41(6):187-95.
2004: Genovese Tiziana; Di Paola Rosanna; Catalano Paolo; Li Jia-He; Xu Weizheng; Massuda Edmond; Caputi Achille P; Zhang Jie; Cuzzocrea Salvatore
Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice.
Critical care medicine 2004;32(6):1365-74.
2004: Wang Zhi-Qiang; Porreca Frank; Cuzzocrea Salvatore; Galen Karen; Lightfoot Richard; Masini Emanuela; Muscoli Carolina; Mollace Vincenzo; Ndengele Michael; Ischiropoulos Harry; Salvemini Daniela
A newly identified role for superoxide in inflammatory pain.
The Journal of pharmacology and experimental therapeutics 2004;309(3):869-78.
2004: Imperatore Francesco; Cuzzocrea Salvatore; Luongo Carlo; Liguori Giovanni; Scafuro Antonella; De Angelis Antonella; Rossi Francesco; Caputi Achille P; Filippelli Amelia
Hyperbaric oxygen therapy prevents vascular derangement during zymosan-induced multiple-organ-failure syndrome.
Intensive care medicine 2004;30(6):1175-81.
2004: Di Paola Rosanna; Genovese Tiziana; Caputi Achille P; Threadgill Mike; Thiemermann Christoph; Cuzzocrea Salvatore
Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.
European journal of pharmacology 2004;492(2-3):203-10.
2004: Cuzzocrea Salvatore; Thiemermann Christoph; Salvemini Daniela
Potential therapeutic effect of antioxidant therapy in shock and inflammation.
Current medicinal chemistry 2004;11(9):1147-62.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Britti Domenico; Patel Nimesh S A; Di Paola Rosanna; Genovese Tiziana; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein.
Intensive care medicine 2004;30(5):951-6.
2004: Cuzzocrea Salvatore; Dugo Laura; Patel Nimesh S A; Di Paola Rosanna; Cockerill Gillian W; Genovese Tiziana; Thiemermann Christoph
High-density lipoproteins reduce the intestinal damage associated with ischemia/reperfusion and colitis.
Shock (Augusta, Ga.) 2004;21(4):342-51.
2004: Di Paola R; Marzocco S; Mazzon E; Dattola F; Rotondo F; Britti D; De Majo M; Genovese T; Cuzzocrea S
Effect of aminoguanidine in ligature-induced periodontitis in rats.
Journal of dental research 2004;83(4):343-8.
2004: Fries Walter; Mazzon Emanuela; Sturiale Sergio; Giofré Maria R; Lo Presti Maria A; Cuzzocrea Salvatore; Campo Giuseppe M; Caputi Achille P; Longo Giuseppe; Sturniolo Giacomo C
A protective effect of the synthetic coumarine derivative Cloricromene against DNB-colitis in the rat.
Life sciences 2004;74(22):2749-56.
2004: d'Emmanuele di Villa Bianca Roberta; Marzocco Stefania; Di Paola Rosanna; Autore Giuseppina; Pinto Aldo; Cuzzocrea Salvatore; Sorrentino Raffaella
Melatonin prevents lipopolysaccharide-induced hyporeactivity in rat.
Journal of pineal research 2004;36(3):146-54.
2004: Dugo Laura; Marzocco Stefania; Mazzon Emanuela; Di Paola Rosanna; Genovese Tiziana; Caputi Achille P; Cuzzocrea Salvatore
Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation.
British journal of pharmacology 2004;141(6):979-87.
2004: Chatterjee Prabal K; Patel Nimesh S A; Kvale Espen O; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Sharpe Martyn A; Di Paola Rosanna; Cuzzocrea Salvatore; Thiemermann Christoph
EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney.
American journal of nephrology 2004;24(2):165-77.
2004: Chatterjee Prabal Kumar; Patel Nimesh S A; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Britti Domenico; Eberhardt Wolfgang; Pfeilschifter Josef; Thiemermann Christoph
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.
Cardiovascular research 2004;61(3):630-43.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Patel Nimesh S A; Di Paola Rosanna; Genovese Tiziana; Chatterjee Prabal K; Fulia Francesco; Cuzzocrea Elisabetta; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice.
Critical care medicine 2004;32(2):457-66.
2004: Marfella Raffaele; Di Filippo Clara; Esposito Katherine; Nappo Francesco; Piegari Elena; Cuzzocrea Salvatore; Berrino Liberato; Rossi Francesco; Giugliano Dario; D'Amico Michele
Absence of inducible nitric oxide synthase reduces myocardial damage during ischemia reperfusion in streptozotocin-induced hyperglycemic mice.
Diabetes 2004;53(2):454-62.
2004: Chatterjee Prabal K; Chatterjee Bristi E; Pedersen Helene; Sivarajah Ahila; McDonald Michelle C; Mota-Filipe Helder; Brown Paul A J; Stewart Keith N; Cuzzocrea Salvatore; Threadgill Michael D; Thiemermann Christoph
5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.
Kidney international 2004;65(2):499-509.
2004: Marzocco Stefania; Di Paola Rosanna; Serraino Ivana; Sorrentino Raffaella; Meli Rosaria; Mattaceraso Giuseppina; Cuzzocrea Salvatore; Pinto Aldo; Autore Giuseppina
Effect of methylguanidine in carrageenan-induced acute inflammation in the rats.
European journal of pharmacology 2004;484(2-3):341-50.
2004: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Di Paola Rosanna; Caputi Achille P; Salvemini D
Superoxide: a key player in hypertension.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):94-101.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Maffia Pasquale; Patel Nimesh S A; Di Paola Rosanna; Ialenti Armando; Genovese Tiziana; Chatterjee Prabal K; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation.
European journal of pharmacology 2004;483(1):79-93.
2004: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Genovese Tiziana; Serraino Ivana; Dugo Laura; Cuzzocrea Elisabetta; Fulia Francesco; Caputi Achille P; Salvemini Daniela
Protective effects of M40401, a selective superoxide dismutase mimetic, on zymosan-induced nonseptic shock.
Critical care medicine 2004;32(1):157-67.
2004: Marzocco Stefania; Di Paola Rosanna; Autore Giuseppina; Mazzon Emanuela; Pinto Aldo; Caputi Achille P; Thiemermann Cristoph; Cuzzocrea Salvatore
Calpain inhibitor I reduces intestinal ischemia-reperfusion injury in the rat.
Shock (Augusta, Ga.) 2004;21(1):38-44.
2003: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Patel Nimesh S A; Serraino Ivana; Di Paola Rosanna; Genovese Tiziana; Britti Domenico; De Maio Massimo; Caputi Achille P; Thiemermann Christoph
Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma.
Arthritis and rheumatism 2003;48(12):3544-56.
2003: Chatterjee Prabal K; di Villa Bianca Roberta D'Emmanuele; Sivarajah Ahila; McDonald Michelle C; Cuzzocrea Salvatore; Thiemermann Christoph
Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney.
European journal of pharmacology 2003;482(1-3):271-80.
2003: McDonald Michelle C; Dhadly Pal; Cockerill Gillian W; Cuzzocrea Salvatore; Mota-Filipe Helder; Hinds Charles J; Miller Norman E; Thiemermann Christoph
Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock.
Shock (Augusta, Ga.) 2003;20(6):551-7.
2003: Virlos Ioannis; Mazzon Emanuela; Serraino Ivana; Di Paola Rosanna; Genovese Tiziana; Britti Domenico; Thiemerman Christoph; Siriwardena Ajith; Cuzzocrea Salvatore
Pyrrolidine dithiocarbamate reduces the severity of cerulein-induced murine acute pancreatitis.
Shock (Augusta, Ga.) 2003;20(6):544-50.
2003: Cuzzocrea Salvatore
Emerging biotherapies for inflammatory bowel disease.
Expert opinion on emerging drugs 2003;8(2):339-47.
2003: Chatterjee Prabal K; Patel Nimesh S A; Kvale Espen O; Brown Paul A J; Stewart Keith N; Britti Domenico; Cuzzocrea Salvatore; Mota-Filipe Helder; Thiemermann Christoph
The tyrosine kinase inhibitor tyrphostin AG126 reduces renal ischemia/reperfusion injury in the rat.
Kidney international 2003;64(5):1605-19.
2003: Cuzzocrea Salvatore; Rossi Antonietta; Pisano Barbara; Di Paola Rosanna; Genovese Tiziana; Patel Nimesh S A; Cuzzocrea Elisabetta; Ianaro Angela; Sautebin Lidia; Fulia Francesco; Chatterjee Prabal K; Caputi Achille P; Thiemermann Christoph
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice.
Intensive care medicine 2003;29(11):2016-25.
2003: Ianaro Angela; Maffia Pasquale; Cuzzocrea Salvatore; Mazzon Elena; Santoro Maria Gabriella; Di Rosa Massimo; Ialenti Armando
2-Cyclopenten-1-one and prostaglandin J2 reduce restenosis after balloon angioplasty in rats: role of NF-kappaB.
FEBS letters 2003;553(1-2):21-7.
2003: Muscoli Carolina; Cuzzocrea Salvatore; Riley Dennis P; Zweier Jay L; Thiemermann Christoph; Wang Zhi-Qiang; Salvemini Daniela
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies.
British journal of pharmacology 2003;140(3):445-60.
2003: van de Loo Fons A J; Bennink Miranda B; Arntz Onno J; Smeets Ruben L; Lubberts Erik; Joosten Leo A B; van Lent Peter L E M; Coenen-de Roo Christina J J; Cuzzocrea Salvatore; Segal Brahm H; Holland Steven M; van den Berg Wim B
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models.
The American journal of pathology 2003;163(4):1525-37.
2003: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Patel Nimesh S A; Di Paola Rosanna; Genovese Tiziana; Chatterjee Prabal K; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
British journal of pharmacology 2003;140(2):366-76.
2003: McDonald Michelle; Abdelrahman Maha; Cuzzocrea Salvatore; Thiemermann Christoph
Tyrphostin reduces the organ injury in haemorrhagic shock: role of inducible nitric oxide synthase.
Resuscitation 2003;58(3):349-61.
2003: Cuzzocrea Salvatore; Rossi Antonietta; Serraino Ivana; Di Paola Rosanna; Dugo Laura; Genovese Tiziana; Britti Domenico; Sciarra Giuseppe; De Sarro Angelina; Caputi Achille P; Sautebin Lidia
5-lipoxygenase knockout mice exhibit a resistance to acute pancreatitis induced by cerulein.
Immunology 2003;110(1):120-30.
2003: Cuzzocrea Salvatore; Rossi Antonietta; Serraino Ivana; Di Paola Rosanna; Dugo Laura; Genovese Tiziana; Caputi Achille P; Sautebin Lidia
5-lipoxygenase knockout mice exhibit a resistance to splanchnic artery occlusion shock.
Shock (Augusta, Ga.) 2003;20(3):230-6.
2003: Rossi Antonietta; Serraino Ivana; Dugo Paola; Di Paola Rosanna; Mondello Luigi; Genovese Tiziana; Morabito Domenica; Dugo Giovanni; Sautebin Lidia; Caputi Achille P; Cuzzocrea Salvatore
Protective effects of anthocyanins from blackberry in a rat model of acute lung inflammation.
Free radical research 2003;37(8):891-900.
2003: Sivarajah Ahila; Chatterjee Prabal K; Patel Nimesh S A; Todorovic Zoran; Hattori Yoshiyuki; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Cuzzocrea Salvatore; Thiemermann Christoph
Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury.
American journal of nephrology 2003;23(4):267-76.
2003: Thiemermann Christoph; Patel Nimesh S A; Kvale Espen O; Cockerill Gillian W; Brown Paul A J; Stewart Keith N; Cuzzocrea Salvatore; Britti Domenico; Mota-Filipe Helder; Chatterjee Prabal K
High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury.
Journal of the American Society of Nephrology : JASN 2003;14(7):1833-43.
2003: Serraino Ivana; Dugo Laura; Dugo Paola; Mondello Luigi; Mazzon Emanuela; Dugo Giovanni; Caputi Achille Patrizio; Cuzzocrea Salvatore
Protective effects of cyanidin-3-O-glucoside from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure.
Life sciences 2003;73(9):1097-114.
2003: Cuzzocrea Salvatore; Rossi Antonietta; Serraino Ivana; Mazzon Emanuela; Di Paola Rosanna; Dugo Laura; Genovese Tiziana; Calabrò Barbara; Caputi Achille P; Sautebin Lidia
5-Lipoxygenase knockout mice exhibit a resistance to pleurisy and lung injury caused by carrageenan.
Journal of leukocyte biology 2003;73(6):739-46.
2003: Samlowski Wolfram E; Petersen Ryan; Cuzzocrea Salvatore; Macarthur Heather; Burton Damali; McGregor John R; Salvemini Daniela
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects.
Nature medicine 2003;9(6):750-5.
2003: Cuzzocrea Salvatore; Persichini Tiziana; Dugo Laura; Colasanti Marco; Musci Giovanni
Copper induces type II nitric oxide synthase in vivo.
Free radical biology & medicine 2003;34(10):1253-62.
2003: Marzocca C; Vannacci A; Cuzzocrea S; Salvemini D; Mannaioni P F; Masini E
Effects of the SOD mimetic, M40403, on prostaglandin production in an in vivo model of ischemia and reperfusion in rat heart.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52 Suppl 1():S23-4.
2003: McDonald Michelle C; d'Emmanuele di Villa Bianca Roberta; Wayman Nicole S; Pinto Aldo; Sharpe Martyn A; Cuzzocrea Salvatore; Chatterjee Prabal K; Thiemermann Christoph
A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock.
European journal of pharmacology 2003;466(1-2):181-9.
2003: Chatterjee Prabal K; Patel Nimesh S A; Sivarajah Ahila; Kvale Espen O; Dugo Laura; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Britti Domenico; Yaqoob Muhammad M; Thiemermann Christoph
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury.
Kidney international 2003;63(3):853-65.
2003: Bucolo Claudio; Cuzzocrea Salvatore; Mazzon Emanuela; Caputi Achille P
Effects of cloricromene, a coumarin derivative, on endotoxin-induced uveitis in Lewis rats.
Investigative ophthalmology & visual science 2003;44(3):1178-84.
2003: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Genovese Tiziana; Di Paola Rosanna; Ruggeri Zaira; Vegeto Elisabetta; Caputi Achille P; Van De Loo Fons A J; Puzzolo Domenico; Maggi Adriana
Inducible nitric oxide synthase mediates bone loss in ovariectomized mice.
Endocrinology 2003;144(3):1098-107.
2003: Mazzon E; Cuzzocrea S
Role of iNOS in hepatocyte tight junction alteration in mouse model of experimental colitis.
Cellular and molecular biology (Noisy-le-Grand, France) 2003;49(1):45-57.
2003: Cuzzocrea Salvatore; Ianaro Angela; Wayman Nicole S; Mazzon Emanuela; Pisano Barbara; Dugo Laura; Serraino Ivana; Di Paola Rosanna; Chatterjee Prabal K; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat.
British journal of pharmacology 2003;138(4):678-88.
2003: Salvemini Daniela; Cuzzocrea Salvatore
Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine.
Critical care medicine 2003;31(1 Suppl):S29-38.
2003: Rossi Antonietta; Cuzzocrea Salvatore; Mazzon Emanuela; Serraino Ivana; De Sarro Angela; Dugo Laura; Felice Maria Rosa; Van de Loo Fons A J; Di Rosa Massimo; Musci Giovanni; Caputi Achille P; Sautebin Lidia
Regulation of prostaglandin generation in carrageenan-induced pleurisy by inducible nitric oxide synthase in knockout mice.
Life sciences 2003;72(10):1199-208.
2003: Salvemini Daniela; Ischiropoulos Harry; Cuzzocrea Salvatore
Roles of nitric oxide and superoxide in inflammation.
Methods in molecular biology (Clifton, N.J.) 2003;225():291-303.
2002: McDonald M C; Izumi M; Cuzzocrea S; Thiemermann C
A novel, potent and selective inhibitor of the activity of inducible nitric oxide synthase (GW274150) reduces the organ injury in hemorrhagic shock.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2002;53(4 Pt 1):555-69.
2002: Patel Nimesh S A; Chatterjee Prabal K; Chatterjee Bristi E; Cuzzocrea Salvatore; Serraino Ivana; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Thiemermann Christoph
TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney.
Free radical biology & medicine 2002;33(11):1575-89.
2002: Mota-Filipe Helder; Sepodes Bruno; McDonald Michelle C; Cuzzocrea Salvatore; Pinto Rui; Thiemermann Christoph
The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(11):BR444-53.
2002: Mazzon Emanuela; De Sarro Angela; Caputi Achille P; Cuzzocrea Salvatore
Role of tight junction derangement in the endothelial dysfunction elicited by exogenous and endogenous peroxynitrite and poly(ADP-ribose) synthetase.
Shock (Augusta, Ga.) 2002;18(5):434-9.
2002: Salvemini Daniela; Cuzzocrea Salvatore
Oxidative stress in septic shock and disseminated intravascular coagulation.
Free radical biology & medicine 2002;33(9):1173-85.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; Serraino Ivana; Dugo Laura; Centorrino Tommaso; Barbera Alberto; Ciccolo Antonio; Fulia Francesco; McDonald Michelle C; Caputi Achille P; Thiemermann Christoph
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat.
Critical care medicine 2002;30(10):2284-94.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; McDonald Michelle C; Dugo Laura; Di Paola Rosanna; Serraino Ivana; Britti Domenico; Caputi Achille P; Thiemermann Christoph
Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis.
European journal of pharmacology 2002;453(1):119-29.
2002: Chatterjee Prabal K; Zacharowski Kai; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Thiemermann Christoph
Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury.
Kidney international 2002;62(4):1249-63.
2002: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Di Paola Rosanna; Britti Domenico; De Sarro Angela; Pierpaoli Simone; Caputi Achille; Masini Emanuela; Salvemini Daniela
A role for superoxide in gentamicin-mediated nephropathy in rats.
European journal of pharmacology 2002;450(1):67-76.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; Dugo Laura; De Sarro Angela; Van de Loo Fons A J; Caputi Achille P; Thiemermann Christoph
Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury.
Shock (Augusta, Ga.) 2002;18(2):169-76.
2002: Mazzon Emanuela; Puzzolo Domenico; Caputi Achille P; Cuzzocrea Salvatore
Role of IL-10 in hepatocyte tight junction alteration in mouse model of experimental colitis.
Molecular medicine (Cambridge, Mass.) 2002;8(7):353-66.
2002: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Di Paola Rosanna; Genovese Tiziana; De Sarro Angela; Caputi Achille P
Absence of endogenous interleukin-10 enhances the evolution of acute lung injury.
European cytokine network 2002;13(3):285-97.
2002: Ottaná Rosaria; Mazzon Emanuela; Dugo Laura; Monforte Francesca; Maccari Rosanna; Sautebin Lidia; De Luca Grazia; Vigorita Maria Gabriella; Alcaro Stefano; Ortuso Francesco; Caputi Achille P; Cuzzocrea Salvatore
Modeling and biological evaluation of 3,3'-(1,2-ethanediyl)bis[2-(4-methoxyphenyl)-thiazolidin-4-one], a new synthetic cyclooxygenase-2 inhibitor.
European journal of pharmacology 2002;448(1):71-80.
2002: Mazzon Emanuela; Dugo Laura; Li Jia-He; Di Paola Rosanna; Genovese Tiziana; Caputi Achille P; Zhang Jie; Cuzzocrea Salvatore
GPI 6150, a PARP inhibitor, reduces the colon injury caused by dinitrobenzene sulfonic acid in the rat.
Biochemical pharmacology 2002;64(2):327-37.
2002: Masini Emanuela; Cuzzocrea Salvatore; Mazzon Emanuela; Marzocca Cosimo; Mannaioni Pier Francesco; Salvemini Daniela
Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo.
British journal of pharmacology 2002;136(6):905-17.
2002: Wayman Nicole S; Hattori Yoshiyuki; McDonald Michelle C; Mota-Filipe Helder; Cuzzocrea Salvatore; Pisano Babrbara; Chatterjee Prabal K; Thiemermann Christoph
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(9):1027-40.
2002: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Centorrino Tommaso; Ciccolo Antonio; McDonald Michelle C; de Sarro Agelina; Caputi Achille P; Thiemermann Christoph
Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice.
Cytokine 2002;18(5):274-85.
2002: Salvemini Daniela; Cuzzocrea Salvatore
Superoxide, superoxide dismutase and ischemic injury.
Current opinion in investigational drugs (London, England : 2000) 2002;3(6):886-95.
2002: Dugo L; Chatterjee P K; Mazzon E; McDonald M C; Paola R Di; Fulia F; Caputi A P; Thiemermann C; Cuzzocrea S
The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat.
Intensive care medicine 2002;28(6):775-88.
2002: Salvemini Daniela; Riley Dennis P; Cuzzocrea Salvatore
SOD mimetics are coming of age.
Nature reviews. Drug discovery 2002;1(5):367-74.
2002: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Centorrino Tommaso; Ciccolo Antonio; Van de Loo Fons A J; Britti Domenico; Caputi Achille P; Thiemermann Christoph
Inducible nitric oxide synthase-deficient mice exhibit resistance to the acute pancreatitis induced by cerulein.
Shock (Augusta, Ga.) 2002;17(5):416-22.
2002: Cuzzocrea Salvatore; Wayman Nicole S; Mazzon Emanuela; Dugo Laura; Di Paola Rosanna; Serraino Ivana; Britti Domenico; Chatterjee Prabal K; Caputi Achille P; Thiemermann Christoph
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation.
Molecular pharmacology 2002;61(5):997-1007.
2002: Mazzon Emanuela; Dugo Laura; De Sarro Angelina; Li Jia-He; Caputi Achille P; Zhang Jie; Cuzzocrea Salvatore
Beneficial effects of GPI 6150, an inhibitor of poly(ADP-ribose) polymerase in a rat model of splanchnic artery occlusion and reperfusion.
Shock (Augusta, Ga.) 2002;17(3):222-7.
2002: Chatterjee Prabal K; Patel Nimesh S A; Kvale Espen O; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Thiemermann Christoph
Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury.
Kidney international 2002;61(3):862-71.
2002: Cuzzocrea Salvatore; Mazzon Emanuela; Sautebin Lidia; Dugo Laura; Serraino Ivana; De Sarro Angela; Caputi Achille P
Protective effects of Celecoxib on lung injury and red blood cells modification induced by carrageenan in the rat.
Biochemical pharmacology 2002;63(4):785-95.
2002: Cuzzocrea Salvatore; Reiter Russel J
Pharmacological actions of melatonin in acute and chronic inflammation.
Current topics in medicinal chemistry 2002;2(2):153-65.
2002: El-Sokkary Gamal H; Omar Hosam M; Hassanein Abdel-Fattah M M; Cuzzocrea Salvatore; Reiter Russel J
Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni.
Free radical biology & medicine 2002;32(4):319-32.
2002: Cuzzocrea Salvatore; McDonald Michelle C; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Threadgill Mike; Caputi Achille P; Thiemermann Christoph
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury.
Biochemical pharmacology 2002;63(2):293-304.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Britti Domenico; Mazzullo Giuseppe; Caputi Achille P; Thiemermann Christoph
Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation.
British journal of pharmacology 2002;135(2):496-510.
2002: Salvemini Daniela; Muscoli Carolina; Riley Dennis P; Cuzzocrea Salvatore
Superoxide dismutase mimetics.
Pulmonary pharmacology & therapeutics 2002;15(5):439-47.
2001: Gitto E; Karbownik M; Reiter R J; Tan D X; Cuzzocrea S; Chiurazzi P; Cordaro S; Corona G; Trimarchi G; Barberi I
Effects of melatonin treatment in septic newborns.
Pediatric research 2001;50(6):756-60.
2001: Cuzzocrea S; Mazzon E; Dugo L; Caputi A P; Riley D P; Salvemini D
Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis.
European journal of pharmacology 2001;432(1):79-89.
2001: Cuzzocrea S; Mazzon E; Serraino I; Dugo L; Centorrino T; Ciccolo A; Sautebin L; Caputi A P
Celecoxib, a selective cyclo-oxygenase-2 inhibitor reduces the severity of experimental colitis induced by dinitrobenzene sulfonic acid in rats.
European journal of pharmacology 2001;431(1):91-102.
2001: Fulia F; Gitto E; Cuzzocrea S; Reiter R J; Dugo L; Gitto P; Barberi S; Cordaro S; Barberi I
Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin.
Journal of pineal research 2001;31(4):343-9.
2001: Cuzzocrea S; Mazzon E; Dugo L; Serraino I; Britti D; De Maio M; Caputi A P
Absence of endogeneous interleukin-10 enhances the evolution of murine type-II collagen-induced arthritis.
European cytokine network 2001;12(4):568-80.
2001: Gitto E; Tan D X; Reiter R J; Karbownik M; Manchester L C; Cuzzocrea S; Fulia F; Barberi I
Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates.
The Journal of pharmacy and pharmacology 2001;53(10):1393-401.
2001: Cuzzocrea S; Reiter R J
Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury.
European journal of pharmacology 2001;426(1-2):1-10.
2001: Dugo L; Serraino I; Fulia F; De Sarro A; Caputi A P; Cuzzocrea S
Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation.
Journal of pineal research 2001;31(1):76-84.
2001: Cuzzocrea S; Mazzon E; Sautebin L; Serraino I; Dugo L; Calabró G; Caputi A P; Maggi A
The protective role of endogenous estrogens in carrageenan-induced lung injury in the rat.
Molecular medicine (Cambridge, Mass.) 2001;7(7):478-87.
2001: Mazzon E; Britti D; De Sarro A; Caputi A P; Cuzzocrea S
Effect of N-acetylcysteine on gentamicin-mediated nephropathy in rats.
European journal of pharmacology 2001;424(1):75-83.
2001: Cuzzocrea S; Mazzon E; Dugo L; Barbera A; Centorrino T; Ciccolo A; Fonti M T; Caputi A P
Inducible nitric oxide synthase knockout mice exhibit resistance to the multiple organ failure induced by zymosan.
Shock (Augusta, Ga.) 2001;16(1):51-8.
2001: Chatterjee P K; Brown P A; Cuzzocrea S; Zacharowski K; Stewart K N; Mota-Filipe H; McDonald M C; Thiemermann C
Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat.
Kidney international 2001;59(6):2073-83.
2001: Cuzzocrea S; Mazzon E; Dugo L; Serraino I; Ciccolo A; Centorrino T; De Sarro A; Caputi A P
Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(7):1187-200.
2001: Cuzzocrea S; McDonald M C; Mazzon E; Mota-Filipe H; Centorrino T; Terranova M L; Ciccolo A; Britti D; Caputi A P; Thiemermann C
Calpain inhibitor I reduces colon injury caused by dinitrobenzene sulphonic acid in the rat.
Gut 2001;48(4):478-88.
2001: Mazzon E; Serraino I; Li J H; Dugo L; Caputi A P; Zhang J; Cuzzocrea S
GPI 6150, a poly (ADP-ribose) polymerase inhibitor, exhibits an anti-inflammatory effect in rat models of inflammation.
European journal of pharmacology 2001;415(1):85-94.
2001: Cuzzocrea S; Riley D P; Caputi A P; Salvemini D
Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury.
Pharmacological reviews 2001;53(1):135-59.
2001: Salvemini D; Mazzon E; Dugo L; Riley D P; Serraino I; Caputi A P; Cuzzocrea S
Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403.
British journal of pharmacology 2001;132(4):815-27.
2001: Cuzzocrea S; McDonald M C; Mazzon E; Filipe H M; Centorrino T; Lepore V; Terranova M L; Ciccolo A; Caputi A P; Thiemermann C
Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat.
Critical care medicine 2001;29(1):102-11.
2001: Cuzzocrea S; Mazzon E; Serraino I; Lepore V; Terranova M L; Ciccolo A; Caputi A P
Melatonin reduces dinitrobenzene sulfonic acid-induced colitis.
Journal of pineal research 2001;30(1):1-12.
2001: Cuzzocrea S; Mazzon E; Dugo L; Caputi A P; Aston K; Riley D P; Salvemini D
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion.
British journal of pharmacology 2001;132(1):19-29.
2001: McDonald M C; Mota-Filipe H; Paul A; Cuzzocrea S; Abdelrahman M; Harwood S; Plevin R; Chatterjee P K; Yaqoob M M; Thiemermann C
Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(1):171-186.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Siriwardena D; Serraino I; Dugo L; Britti D; Mazzullo G; Caputi A P; Thiemermann C
Calpain inhibitor I reduces the development of acute and chronic inflammation.
The American journal of pathology 2000;157(6):2065-79.
2000: Cuzzocrea S; Mazzon E; Bevilaqua C; Costantino G; Britti D; Mazzullo G; De Sarro A; Caputi A P
Cloricromene, a coumarine derivative, protects against collagen-induced arthritis in Lewis rats.
British journal of pharmacology 2000;131(7):1399-407.
2000: Cuzzocrea S; Mazzon E; Calabro G; Dugo L; De Sarro A; van De LOO F A; Caputi A P
Inducible nitric oxide synthase-knockout mice exhibit resistance to pleurisy and lung injury caused by carrageenan.
American journal of respiratory and critical care medicine 2000;162(5):1859-66.
2000: Cuzzocrea S; Costantino G; Gitto E; Mazzon E; Fulia F; Serraino I; Cordaro S; Barberi I; De Sarro A; Caputi A P
Protective effects of melatonin in ischemic brain injury.
Journal of pineal research 2000;29(4):217-27.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Dugo L; Lepore V; Fonti M T; Ciccolo A; Terranova M L; Caputi A P; Thiemermann C
Tempol, a membrane-permeable radical scavenger, reduces dinitrobenzene sulfonic acid-induced colitis.
European journal of pharmacology 2000;406(1):127-37.
2000: Cuzzocrea S; Mazzon E; De Sarro A; Caputi A P
Role of free radicals and poly(ADP-ribose) synthetase in intestinal tight junction permeability.
Molecular medicine (Cambridge, Mass.) 2000;6(9):766-78.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Mota-Filipe H; Lepore V; Ciccolo A; Terranova M L; Britti D; Caputi A P; Thiemermann C
The tyrosine kinase inhibitor tyrphostin AG 126 reduced the development of colitis in the rat.
Laboratory investigation; a journal of technical methods and pathology 2000;80(9):1439-53.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Siriwardena D; Costantino G; Fulia F; Cucinotta G; Gitto E; Cordaro S; Barberi I; De Sarro A; Caputi A P; Thiemermann C
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury.
Brain research 2000;875(1-2):96-106.
2000: Cuzzocrea S; Mazzon E; Costantino G; Serraino I; De Sarro A; Caputi A P
Effects of n-acetylcysteine in a rat model of ischemia and reperfusion injury.
Cardiovascular research 2000;47(3):537-48.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Filipe H M; Costantino G; Caputi A P; Thiemermann C
Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of splanchnic artery occlusion and reperfusion.
Shock (Augusta, Ga.) 2000;14(2):150-6.
2000: Chatterjee P K; Cuzzocrea S; Brown P A; Zacharowski K; Stewart K N; Mota-Filipe H; Thiemermann C
Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat.
Kidney international 2000;58(2):658-73.
2000: Cuzzocrea S; Mazzon E; Costantino G; Serraino I; Dugo L; Calabrò G; Cucinotta G; De Sarro A; Caputi A P
Beneficial effects of n-acetylcysteine on ischaemic brain injury.
British journal of pharmacology 2000;130(6):1219-26.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Siriwardena D; Calabrò G; Britti D; Mazzullo G; De Sarro A; Caputi A P; Thiemermann C
The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation.
The American journal of pathology 2000;157(1):145-58.
2000: Cuzzocrea S; Santagati S; Sautebin L; Mazzon E; Calabrò G; Serraino I; Caputi A P; Maggi A
17beta-estradiol antiinflammatory activity in carrageenan-induced pleurisy.
Endocrinology 2000;141(4):1455-63.
2000: Chatterjee P K; Zacharowski K; Cuzzocrea S; Otto M; Thiemermann C
Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(5):641-51.
2000: Cuzzocrea S; Imperatore F; Costantino G; Luongo C; Mazzon E; Scafuro M A; Mangoni G; Caputi A P; Rossi F; Filippelli A
Role of hyperbaric oxygen exposure in reduction of lipid peroxidation and in multiple organ failure induced by zymosan administration in the rat.
Shock (Augusta, Ga.) 2000;13(3):197-203.
2000: Cuzzocrea S; McDonald M C; Filipe H M; Costantino G; Mazzon E; Santagati S; Caputi A P; Thiemermann C
Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy.
European journal of pharmacology 2000;390(1-2):209-22.
2000: Cuzzocrea S; McDonald M C; Mota-Filipe H; Mazzon E; Costantino G; Britti D; Mazzullo G; Caputi A P; Thiemermann C
Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of collagen-induced arthritis.
Arthritis and rheumatism 2000;43(2):320-8.
2000: Cuzzocrea S; Costantino G; Mazzon E; Micali A; De Sarro A; Caputi A P
Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion.
Journal of pineal research 2000;28(1):52-63.
1999: Cuzzocrea S; Costantino G; Mazzon E; De Sarro A; Caputi A P
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
British journal of pharmacology 1999;128(6):1241-51.
1999: El-Sokkary G H; Reiter R J; Cuzzocrea S; Caputi A P; Hassanein A F; Tan D X
Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan.
Shock (Augusta, Ga.) 1999;12(5):402-8.
1999: Cuzzocrea S; Tan D X; Costantino G; Mazzon E; Caputi A P; Reiter R J
The protective role of endogenous melatonin in carrageenan-induced pleurisy in the rat.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(14):1930-8.
1999: Cuzzocrea S; Sautebin L; De Sarro G; Costantino G; Rombolà L; Mazzon E; Ialenti A; De Sarro A; Ciliberto G; Di Rosa M; Caputi A P; Thiemermann C
Role of IL-6 in the pleurisy and lung injury caused by carrageenan.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):5094-104.
1999: Salvemini D; Wang Z Q; Zweier J L; Samouilov A; Macarthur H; Misko T P; Currie M G; Cuzzocrea S; Sikorski J A; Riley D P
A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats.
Science (New York, N.Y.) 1999;286(5438):304-6.
1999: Mota-Filipe H; McDonald M C; Cuzzocrea S; Thiemermann C
A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock.
Shock (Augusta, Ga.) 1999;12(4):255-61.
1999: Cuzzocrea S; De Sarro G; Costantino G; Ciliberto G; Mazzon E; De Sarro A; Caputi A P
IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock.
Journal of leukocyte biology 1999;66(3):471-80.
1999: McDonald M C; Zacharowski K; Bowes J; Cuzzocrea S; Thiemermann C
Tempol reduces infarct size in rodent models of regional myocardial ischemia and reperfusion.
Free radical biology & medicine 1999;27(5-6):493-503.
1999: Chatterjee P K; Cuzzocrea S; Thiemermann C
Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress.
Kidney international 1999;56(3):973-84.
1999: Cuzzocrea S; Costantino G; Mazzon E; Caputi A P
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
Critical care medicine 1999;27(8):1524-32.
1999: Cuzzocrea S; Zingarelli B; Costantino G; Sottile A; Teti D; Caputi A P
Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat.
Critical care medicine 1999;27(8):1517-23.
1999: Cuzzocrea S; Costantino G; Mazzon E; Caputi A P
Regulation of prostaglandin production in carrageenan-induced pleurisy by melatonin.
Journal of pineal research 1999;27(1):9-14.
1999: Cuzzocrea S; Costantino G; Mazzon E; Zingarelli B; De Sarro A; Caputi A P
Protective effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in paw oedema induced by carrageenan in the rat.
Biochemical pharmacology 1999;58(1):171-6.
1999: Cuzzocrea S; de Sarro G; Costantino G; Mazzon E; Laurà R; Ciriaco E; de Sarro A; Caputi A P
Role of interleukin-6 in a non-septic shock model induced by zymosan.
European cytokine network 1999;10(2):191-203.
1999: Cuzzocrea S; Costantino G; Zingarelli B; Mazzon E; Micali A; Caputi A P
The protective role of endogenous glutathione in carrageenan-induced pleurisy in the rat.
European journal of pharmacology 1999;372(2):187-97.
1999: Cuzzocrea S; Costantino G; Caputi A P
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Shock (Augusta, Ga.) 1999;11(2):143-8.
1999: Cuzzocrea S; Caputi A P
Protective effect of melatonin on zymosan-induced cellular damage.
Biological signals and receptors 1999;8(1-2):136-42.
1999: Cuzzocrea S; Costantino G; Mazzon E; Caputi A P
Beneficial effects of raxofelast (IRFI 016), a new hydrophilic vitamin E-like antioxidant, in carrageenan-induced pleurisy.
British journal of pharmacology 1999;126(2):407-14.
1999: Cuzzocrea S; Zingarelli B; Costantino G; Caputi A P
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in carrageenan-induced pleurisy.
Free radical biology & medicine 1999;26(1-2):25-33.
1999: Cuzzocrea S; Sautebin L; Costantino G; Rombolà L; Mazzon E; Caputi A P
Regulation of prostaglandin production by inhibition of poly (ADP-ribose) synthase in carrageenan-induced pleurisy.
Life sciences 1999;65(12):1297-304.
1999: Cuzzocrea S; Costantino G; Zingarelli B; Caputi A P
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema.
Life sciences 1999;65(9):957-64.
1998: Costantino G; Cuzzocrea S; Mazzon E; Caputi A P
Protective effects of melatonin in zymosan-activated plasma-induced paw inflammation.
European journal of pharmacology 1998;363(1):57-63.
1998: Luongo C; Imperatore F; Cuzzocrea S; Filippelli A; Scafuro M A; Mangoni G; Portolano F; Rossi F
Effects of hyperbaric oxygen exposure on a zymosan-induced shock model.
Critical care medicine 1998;26(12):1972-6.
1998: Cuzzocrea S; Costantino G; Caputi A P
Protective effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in a non-septic shock model induced by zymosan in the rat.
Journal of pineal research 1998;25(2):78-85.
1998: Cuzzocrea S; Zingarelli B; Costantino G; Caputi A P
Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat.
Journal of pineal research 1998;25(1):24-33.
1998: Cuzzocrea S; Zingarelli B; Caputi A P
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
Shock (Augusta, Ga.) 1998;9(5):336-40.
1998: Cuzzocrea S; Zingarelli B; Caputi A P
Role of peroxynitrite and poly (ADP-ribose) synthetase on cellular energy depletion in carrageenan-induced pleurisy.
Journal of chemotherapy (Florence, Italy) 1998;10(2):153-6.
1998: Cuzzocrea S; Caputi A P; Zingarelli B
Peroxynitrite-mediated DNA strand breakage activates poly (ADP-ribose) synthetase and causes cellular energy depletion in carrageenan-induced pleurisy.
Immunology 1998;93(1):96-101.
1998: Cuzzocrea S; Zingarelli B; Caputi A P
Role of peroxynitrite and poly (ADP-ribosyl) synthetase activation in cardiovascular derangement induced by zymosan in the rat.
Life sciences 1998;63(11):923-33.
1998: Cuzzocrea S; Zingarelli B; Caputi A P
Role of constitutive nitric oxide synthase and peroxynitrite production in a rat model of splanchnic artery occlusion shock.
Life sciences 1998;63(9):789-99.
1998: Cuzzocrea S; Zingarelli B; Villari D; Caputi A P; Longo G
Evidence for in vivo peroxynitrite production in human chronic hepatitis.
Life sciences 1998;63(2):PL25-30.
1997: Cuzzocrea S; Zingarelli B; O'Connor M; Salzman A L; Caputi A P; Szabó C
Role of peroxynitrite and activation of poly (ADP-ribose) synthase in the vascular failure induced by zymosan-activated plasma.
British journal of pharmacology 1997;122(3):493-503.
1997: Cuzzocrea S; Zingarelli B; Sautebin L; Rizzo A; Crisafulli C; Campo G M; Costantino G; Calapai G; Nava F; Di Rosa M; Caputi A P
Multiple organ failure following zymosan-induced peritonitis is mediated by nitric oxide.
Shock (Augusta, Ga.) 1997;8(4):268-75.
1997: Purello D'Ambrosio F; Gangemi S; Ricciardi L; Cuzzocrea S; Di Lorenzo G
Lodoxamide versus spaglumic acid: a comparative double-blind trial on patients suffering from seasonal allergic conjunctivitis induced by Parietaria pollen.
Allergologia et immunopathologia 1997;25(5):233-7.
1997: Nava F; Calapai G; Facciolà G; Cuzzocrea S; Giuliani G; De Sarro A; Caputi A P
Melatonin effects on inhibition of thirst and fever induced by lipopolysaccharide in rat.
European journal of pharmacology 1997;331(2-3):267-74.
1997: Cuzzocrea S; Zingarelli B; Costantino G; Szabó A; Salzman A L; Caputi A P; Szabó C
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion.
British journal of pharmacology 1997;121(6):1065-74.
1997: Cuzzocrea S; Filippelli A; Zingarelli B; Falciani M; Caputi A P; Rossi F
Role of nitric oxide in a nonseptic shock model induced by zymosan in the rat.
Shock (Augusta, Ga.) 1997;7(5):351-7.
1997: Nava F; Calapai G; Facciolá G; Cuzzocrea S; Marciano M C; De Sarro A; Caputi A P
Effects of interleukin-10 on water intake, locomotory activity, and rectal temperature in rat treated with endotoxin.
International journal of immunopharmacology 1997;19(1):31-8.
1997: Cuzzocrea S; Zingarelli B; Calapai G; Nava F; Caputi A P
Zymosan-activated plasma induces paw oedema by nitric oxide and prostaglandin production.
Life sciences 1997;60(3):215-20.
1996: Calapai G; Mazzaglia G; Sautebin L; Costantino G; Marciano M C; Cuzzocrea S; Di Rosa M; Caputi A P
Inhibition of nitric oxide formation reduces voluntary ethanol consumption in the rat.
Psychopharmacology 1996;125(4):398-401.

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