Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Miroslaw Cygler

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Concepts & Ideas

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequence

Phenomena

Living Beings

Physiology

Site-Directed Mutagenesis

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Rangarajan Erumbi S; Proteau Ariane; Cui Qizhi; Logan Susan M; Potetinova Zhanna; Whitfield Dennis; Purisima Enrico O; Cygler Miroslaw; Matte Allan; Sulea Traian; Schoenhofen Ian C
Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
Kozlov Guennadi; Määttänen Pekka; Schrag Joseph D; Hura Greg L; Gabrielli Lisa; Cygler Miroslaw; Thomas David Y; Gehring Kalle
Structure of the noncatalytic domains and global fold of the protein disulfide isomerase ERp72.
Shi Rong; Proteau Ariane; Wagner John; Cui Qizhi; Purisima Enrico O; Matte Allan; Cygler Miroslaw
Trapping open and closed forms of FitE: a group III periplasmic binding protein.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Miroslaw Cygler (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Rangarajan Erumbi S; Proteau Ariane; Cui Qizhi; Logan Susan M; Potetinova Zhanna; Whitfield Dennis; Purisima Enrico O; Cygler Miroslaw; Matte Allan; Sulea Traian; Schoenhofen Ian C
Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
The Journal of biological chemistry 2009;284(31):20989-1000.
2009: Kozlov Guennadi; Määttänen Pekka; Schrag Joseph D; Hura Greg L; Gabrielli Lisa; Cygler Miroslaw; Thomas David Y; Gehring Kalle
Structure of the noncatalytic domains and global fold of the protein disulfide isomerase ERp72.
Structure (London, England : 1993) 2009;17(5):651-9.
2009: Shi Rong; Proteau Ariane; Wagner John; Cui Qizhi; Purisima Enrico O; Matte Allan; Cygler Miroslaw
Trapping open and closed forms of FitE: a group III periplasmic binding protein.
Proteins 2009;75(3):598-609.
2009: Shi Rong; Lamb Sherry S; Zakeri Bijan; Proteau Ariane; Cui Qizhi; Sulea Traian; Matte Allan; Wright Gerard D; Cygler Miroslaw
Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics.
Chemistry & biology 2009;16(4):401-10.
2009: Min Tongpil; Vedadi Masoud; Watson David C; Wasney Gregory A; Munger Christine; Cygler Miroslaw; Matte Allan; Young N Martin
Specificity of Campylobacter jejuni adhesin PEB3 for phosphates and structural differences among its ligand complexes.
Biochemistry 2009;48(14):3057-67.
2009: Morona Renato; Purins Leanne; Tocilj Ante; Matte Allan; Cygler Miroslaw
Sequence-structure relationships in polysaccharide co-polymerase (PCP) proteins.
Trends in biochemical sciences 2009;34(2):78-84.
2009: Zhang Zhenqing; Park Youmie; Kemp Melissa M; Zhao Wenjing; Im A-Rang; Shaya David; Cygler Miroslaw; Kim Yeong Shik; Linhardt Robert J
Liquid chromatography-mass spectrometry to study chondroitin lyase action pattern.
Analytical biochemistry 2009;385(1):57-64.
2008: Shi Rong; Pineda Marco; Ajamian Eunice; Cui Qizhi; Matte Allan; Cygler Miroslaw
Structure of L-xylulose-5-Phosphate 3-epimerase (UlaE) from the anaerobic L-ascorbate utilization pathway of Escherichia coli: identification of a novel phosphate binding motif within a TIM barrel fold.
Journal of bacteriology 2008;190(24):8137-44.
2008: Cui Qizhi; Sulea Traian; Schrag Joseph D; Munger Christine; Hung Ming-Ni; Naïm Marwen; Cygler Miroslaw; Purisima Enrico O
Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex.
Journal of molecular biology 2008;379(4):787-802.
2008: Shaya D; Hahn Bum-Soo; Bjerkan Tonje Marita; Kim Wan Seok; Park Nam Young; Sim Joon-Soo; Kim Yeong-Shik; Cygler M
Composite active site of chondroitin lyase ABC accepting both epimers of uronic acid.
Glycobiology 2008;18(3):270-7.
2008: Tocilj Ante; Munger Christine; Proteau Ariane; Morona Renato; Purins Leanne; Ajamian Eunice; Wagner John; Papadopoulos Magdalene; Van Den Bosch Luisa; Rubinstein John L; Féthière James; Matte Allan; Cygler Miroslaw
Bacterial polysaccharide co-polymerases share a common framework for control of polymer length.
Nature structural & molecular biology 2008;15(2):130-8.
2008: Rangarajan Erumbi S; Ruane Karen M; Sulea Traian; Watson David C; Proteau Ariane; Leclerc Sonia; Cygler Miroslaw; Matte Allan; Young N Martin
Structure and active site residues of PglD, an N-acetyltransferase from the bacillosamine synthetic pathway required for N-glycan synthesis in Campylobacter jejuni.
Biochemistry 2008;47(7):1827-36.
2008: Xiao Zhizhuang; Bergeron Hélène; Grosse Stephan; Beauchemin Manon; Garron Marie-Line; Shaya David; Sulea Traian; Cygler Miroslaw; Lau Peter C K
Improvement of the thermostability and activity of a pectate lyase by single amino acid substitutions, using a strategy based on melting-temperature-guided sequence alignment.
Applied and environmental microbiology 2008;74(4):1183-9.
2008: Rangarajan Erumbi S; Asinas Abdalin; Proteau Ariane; Munger Christine; Baardsnes Jason; Iannuzzi Pietro; Matte Allan; Cygler Miroslaw
Structure of [NiFe] hydrogenase maturation protein HypE from Escherichia coli and its interaction with HypF.
Journal of bacteriology 2008;190(4):1447-58.
2008: Cygler Miroslaw; Hung Ming-ni; Wagner John; Matte Allan
Bacterial structural genomics initiative: overview of methods and technologies applied to the process of structure determination.
Methods in molecular biology (Clifton, N.J.) 2008;426():537-59.
2007: Matte Allan; Jia Zongchao; Sunita S; Sivaraman J; Cygler Miroslaw
Insights into the biology of Escherichia coli through structural proteomics.
Journal of structural and functional genomics 2007;8(2-3):45-55.
2007: Rangarajan Erumbi S; Bhatia Smita; Watson David C; Munger Christine; Cygler Miroslaw; Matte Allan; Young N Martin
Structural context for protein N-glycosylation in bacteria: The structure of PEB3, an adhesin from Campylobacter jejuni.
Protein science : a publication of the Protein Society 2007;16(5):990-5.
2007: Shi Rong; Lamb Sherry S; Bhat Sathesh; Sulea Traian; Wright Gerard D; Matte Allan; Cygler Miroslaw
Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis.
The Journal of biological chemistry 2007;282(17):13073-86.
2007: Minailiuc Ovidiu M; Vavelyuk Olga; Gandhi Shaifali; Hung Ming-Ni; Cygler Miroslaw; Ekiel Irena
NMR structure of YcgL, a conserved protein from Escherichia coli representing the DUF709 family, with a novel alpha/beta/alpha sandwich fold.
Proteins 2007;66(4):1004-7.
2007: Krupa Joanne C; Shaya David; Chi Lianli; Linhardt Robert J; Cygler Miroslaw; Withers Stephen G; Mort John S
Quantitative continuous assay for hyaluronan synthase.
Analytical biochemistry 2007;361(2):218-25.
2006: Rangarajan Erumbi S; Proteau Ariane; Wagner John; Hung Ming-Ni; Matte Allan; Cygler Miroslaw
Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
The Journal of biological chemistry 2006;281(49):37930-41.
2006: Kim Yeon-Gil; Raunser Stefan; Munger Christine; Wagner John; Song Young-Lan; Cygler Miroslaw; Walz Thomas; Oh Byung-Ha; Sacher Michael
The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering.
Cell 2006;127(4):817-30.
2006: Kozlov Guennadi; Maattanen Pekka; Schrag Joseph D; Pollock Stephanie; Cygler Miroslaw; Nagar Bhushan; Thomas David Y; Gehring Kalle
Crystal structure of the bb' domains of the protein disulfide isomerase ERp57.
Structure (London, England : 1993) 2006;14(8):1331-9.
2006: Sunita S; Zhenxing H; Swaathi J; Cygler Miroslaw; Matte Allan; Sivaraman J
Domain organization and crystal structure of the catalytic domain of E.coli RluF, a pseudouridine synthase that acts on 23S rRNA.
Journal of molecular biology 2006;359(4):998-1009.
2006: Rangarajan Erumbi S; Nadeau Guy; Li Yunge; Wagner John; Hung Ming-Ni; Schrag Joseph D; Cygler Miroslaw; Matte Allan
The structure of the exopolyphosphatase (PPX) from Escherichia coli O157:H7 suggests a binding mode for long polyphosphate chains.
Journal of molecular biology 2006;359(5):1249-60.
2006: Shaya David; Tocilj Ante; Li Yunge; Myette James; Venkataraman Ganesh; Sasisekharan Ram; Cygler Miroslaw
Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product.
The Journal of biological chemistry 2006;281(22):15525-35.
2006: Rye Carl S; Matte Allan; Cygler Miroslaw; Withers Stephen G
An atypical approach identifies TYR234 as the key base catalyst in chondroitin AC lyase.
Chembiochem : a European journal of chemical biology 2006;7(4):631-7.
2006: Schoenhofen Ian C; Lunin Vladimir V; Julien Jean-Philippe; Li Yunge; Ajamian Eunice; Matte Allan; Cygler Miroslaw; Brisson Jean-Robert; Aubry Annie; Logan Susan M; Bhatia Smita; Wakarchuk Warren W; Young N Martin
Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori.
The Journal of biological chemistry 2006;281(13):8907-16.
2006: Linhardt Robert J; Avci Fikri Y; Toida Toshihiko; Kim Yeong Shik; Cygler Miroslaw
CS lyases: structure, activity, and applications in analysis and the treatment of diseases.
Advances in pharmacology (San Diego, Calif.) 2006;53():187-215.
2005: Sacher Michael; Di Bacco Alessandra; Lunin Vladimir V; Ye Zheng; Wagner John; Gill Grace; Cygler Miroslaw
The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18326-31.
2005: Kim Min-Sung; Yi Min-Ju; Lee Kwang-Hoon; Wagner John; Munger Christine; Kim Yeon-Gil; Whiteway Malcolm; Cygler Miroslaw; Oh Byung-Ha; Sacher Michael
Biochemical and crystallographic studies reveal a specific interaction between TRAPP subunits Trs33p and Bet3p.
Traffic (Copenhagen, Denmark) 2005;6(12):1183-95.
2005: Rangarajan Erumbi S; Li Yunge; Ajamian Eunice; Iannuzzi Pietro; Kernaghan Stephanie D; Fraser Marie E; Cygler Miroslaw; Matte Allan
Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases.
The Journal of biological chemistry 2005;280(52):42919-28.
2005: Suits Michael D L; Pal Gour P; Nakatsu Kanji; Matte Allan; Cygler Miroslaw; Jia Zongchao
Identification of an Escherichia coli O157:H7 heme oxygenase with tandem functional repeats.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):16955-60.
2005: Raymond Stephane; Tocilj Ante; Ajamian Eunice; Li Yunge; Hung Ming-Ni; Matte Allan; Cygler Miroslaw
Crystal structure of ureidoglycolate hydrolase (AllA) from Escherichia coli O157:H7.
Proteins 2005;61(2):454-9.
2005: Sivaraman J; Myers Rebecca S; Boju Lorena; Sulea Traian; Cygler Miroslaw; Jo Davisson V; Schrag Joseph D
Crystal structure of Methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase HisI.
Biochemistry 2005;44(30):10071-80.
2005: Matte Allan; Louie Gordon V; Sivaraman J; Cygler Miroslaw; Burley Stephen K
Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 4):350-4.
2005: Rangarajan Erumbi S; Li Yunge; Iannuzzi Pietro; Cygler Miroslaw; Matte Allan
Crystal structure of Escherichia coli crotonobetainyl-CoA: carnitine CoA-transferase (CaiB) and its complexes with CoA and carnitinyl-CoA.
Biochemistry 2005;44(15):5728-38.
2005: Tocilj Ante; Schrag Joseph D; Li Yunge; Schneider Barbara L; Reitzer Larry; Matte Allan; Cygler Miroslaw
Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli.
The Journal of biological chemistry 2005;280(16):15800-8.
2005: Lindner Holger A; Nadeau Guy; Matte Allan; Michel Gurvan; Ménard Robert; Cygler Miroslaw
Site-directed mutagenesis of the active site region in the quinate/shikimate 5-dehydrogenase YdiB of Escherichia coli.
The Journal of biological chemistry 2005;280(8):7162-9.
2005: Pajon Anne; Ionides John; Diprose Jon; Fillon Joël; Fogh Rasmus; Ashton Alun W; Berman Helen; Boucher Wayne; Cygler Miroslaw; Deleury Emeline; Esnouf Robert; Janin Joël; Kim Rosalind; Krimm Isabelle; Lawson Catherine L; Oeuillet Eric; Poupon Anne; Raymond Stéphane; Stevens Tim; van Tilbeurgh Herman; Westbrook John; Wood Peter; Ulrich Eldon; Vranken Wim; Xueli Li; Laue Ernest; Stuart David I; Henrick Kim
Design of a data model for developing laboratory information management and analysis systems for protein production.
Proteins 2005;58(2):278-84.
2004: Kozlov Guennadi; Elias Demetra; Semesi Anthony; Yee Adelinda; Cygler Miroslaw; Gehring Kalle
Structural similarity of YbeD protein from Escherichia coli to allosteric regulatory domains.
Journal of bacteriology 2004;186(23):8083-8.
2004: Rangarajan Erumbi S; Li Yunge; Iannuzzi Pietro; Tocilj Ante; Hung Li-Wei; Matte Allan; Cygler Miroslaw
Crystal structure of a dodecameric FMN-dependent UbiX-like decarboxylase (Pad1) from Escherichia coli O157: H7.
Protein science : a publication of the Protein Society 2004;13(11):3006-16.
2004: Lunin Vladimir V; Li Yunge; Schrag Joseph D; Iannuzzi Pietro; Cygler Miroslaw; Matte Allan
Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose.
Journal of bacteriology 2004;186(20):6915-27.
2004: Shaya David; Li Yunge; Cygler Miroslaw
Crystallization and preliminary X-ray analysis of heparinase II from Pedobacter heparinus.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 9):1644-6.
2004: Kozlov Guennadi; Perreault Audrey; Schrag Joseph D; Park Morag; Cygler Miroslaw; Gehring Kalle; Ekiel Irena
Insights into function of PSI domains from structure of the Met receptor PSI domain.
Biochemical and biophysical research communications 2004;321(1):234-40.
2004: Copeland Evelyne H; Ekiel Irena; Cygler Miroslaw
1H, 13C and 15N resonance assignments of human 5,10-methenyltetrahydrofolate synthetase.
Journal of biomolecular NMR 2004;29(4):547-8.
2004: O'Toole Nicholas; Grabowski Marek; Otwinowski Zbyszek; Minor Wladek; Cygler Miroslaw
The structural genomics experimental pipeline: insights from global target lists.
Proteins 2004;56(2):201-10.
2004: Michel Gurvan; Pojasek Kevin; Li Yunge; Sulea Traian; Linhardt Robert J; Raman Rahul; Prabhakar Vikas; Sasisekharan Ram; Cygler Miroslaw
The structure of chondroitin B lyase complexed with glycosaminoglycan oligosaccharides unravels a calcium-dependent catalytic machinery.
The Journal of biological chemistry 2004;279(31):32882-96.
2004: Lunin Vladimir V; Munger Christine; Wagner John; Ye Zheng; Cygler Miroslaw; Sacher Michael
The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling.
The Journal of biological chemistry 2004;279(22):23422-30.
2004: Schrag Joseph D; Cygler Miroslaw
Defining substrate characteristics from 3D structure; perspective on EstA structure.
Structure (London, England : 1993) 2004;12(4):521-2.
2004: Lunin Vladimir V; Li Yunge; Linhardt Robert J; Miyazono Hirofumi; Kyogashima Mamoru; Kaneko Takuji; Bell Alexander W; Cygler Miroslaw
High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism.
Journal of molecular biology 2004;337(2):367-86.
2004: Sivaraman J; Iannuzzi Pietro; Cygler Miroslaw; Matte Allan
Crystal structure of the RluD pseudouridine synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli.
Journal of molecular biology 2004;335(1):87-101.
2004: Kozlov Guennadi; Elias Demetra; Cygler Miroslaw; Gehring Kalle
Structure of GlgS from Escherichia coli suggests a role in protein-protein interactions.
BMC biology 2004;2():10.
2003: Rangarajan S Erumbi; Tocilj Ante; Li Yunge; Iannuzzi Pietro; Matte Allan; Cygler Miroslaw
Molecules of Escherichia coli MobB assemble into densely packed hollow cylinders in a crystal lattice with 75% solvent content.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2348-52.
2003: Lindner Holger A; Lunin Vladimir V; Alary Alain; Hecker Regina; Cygler Miroslaw; Ménard Robert
Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.
The Journal of biological chemistry 2003;278(45):44496-504.
2003: Sivaraman J; Li Yunge; Banks Jerel; Cane David E; Matte Allan; Cygler Miroslaw
Crystal structure of Escherichia coli PdxA, an enzyme involved in the pyridoxal phosphate biosynthesis pathway.
The Journal of biological chemistry 2003;278(44):43682-90.
2003: O'Toole Nicholas; Cygler Miroslaw
The final player in the coenzyme A biosynthetic pathway.
Structure (London, England : 1993) 2003;11(8):899-900.
2003: Volpon Laurent; Lievre Carine; Osborne Michael J; Gandhi Shaifali; Iannuzzi Pietro; Larocque Robert; Cygler Miroslaw; Gehring Kalle; Ekiel Irena
The solution structure of YbcJ from Escherichia coli reveals a recently discovered alphaL motif involved in RNA binding.
Journal of bacteriology 2003;185(14):4204-10.
2003: Matte Allan; Sivaraman J; Ekiel Irena; Gehring Kalle; Jia Zongchao; Cygler Miroslaw
Contribution of structural genomics to understanding the biology of Escherichia coli.
Journal of bacteriology 2003;185(14):3994-4002.
2003: Huang Weijun; Lunin Vladimir V; Li Yunge; Suzuki Sakaru; Sugiura Nobuo; Miyazono Hirofumi; Cygler Miroslaw
Crystal structure of Proteus vulgaris chondroitin sulfate ABC lyase I at 1.9A resolution.
Journal of molecular biology 2003;328(3):623-34.
2003: Michel Gurvan; Roszak Aleksander W; Sauvé Véronique; Maclean John; Matte Allan; Coggins John R; Cygler Miroslaw; Lapthorn Adrian J
Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities.
The Journal of biological chemistry 2003;278(21):19463-72.
2003: Pauly Thomas A; Sulea Traian; Ammirati Mark; Sivaraman J; Danley Dennis E; Griffor Matthew C; Kamath Ajith V; Wang I-K; Laird Ellen R; Seddon Andrew P; Ménard Robert; Cygler Miroslaw; Rath Virginia L
Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry 2003;42(11):3203-13.
2003: O'Toole Nicholas; Barbosa João A R G; Li Yunge; Hung Li-Wei; Matte Allan; Cygler Miroslaw
Crystal structure of a trimeric form of dephosphocoenzyme A kinase from Escherichia coli.
Protein science : a publication of the Protein Society 2003;12(2):327-36.
2003: Schrag Joseph D; Procopio Daniela O; Cygler Miroslaw; Thomas David Y; Bergeron John J M
Lectin control of protein folding and sorting in the secretory pathway.
Trends in biochemical sciences 2003;28(1):49-57.
2003: O'Toole Nicholas; Raymond Stéphane; Cygler Miroslaw
Coverage of protein sequence space by current structural genomics targets.
Journal of structural and functional genomics 2003;4(2-3):47-55.
2002: Chowdhury Shafinaz F; Sivaraman J; Wang Jing; Devanathan Gopal; Lachance Paule; Qi Hongtao; Ménard Robert; Lefebvre Jean; Konishi Yasuo; Cygler Miroslaw; Sulea Traian; Purisima Enrico O
Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides.
Journal of medicinal chemistry 2002;45(24):5321-9.
2002: Sivaraman J; Sauvé Véronique; Matte Allan; Cygler Miroslaw
Crystal structure of Escherichia coli glucose-1-phosphate thymidylyltransferase (RffH) complexed with dTTP and Mg2+.
The Journal of biological chemistry 2002;277(46):44214-9.
2002: Michel Gurvan; Sauvé Véronique; Larocque Robert; Li Yunge; Matte Allan; Cygler Miroslaw
The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot.
Structure (London, England : 1993) 2002;10(10):1303-15.
2002: Jia Jia; Lunin Vladimir V; Sauvé Véronique; Huang Li-Wei; Matte Allan; Cygler Miroslaw
Crystal structure of the YciO protein from Escherichia coli.
Proteins 2002;49(1):139-41.
2002: Rangarajan Erumbi S; Sivaraman J; Matte Allan; Cygler Miroslaw
Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli.
Proteins 2002;48(4):737-40.
2002: Capila Ishan; Wu Yi; Rethwisch David W; Matte Allan; Cygler Miroslaw; Linhardt Robert J
Role of arginine 292 in the catalytic activity of chondroitin AC lyase from Flavobacterium heparinum.
Biochimica et biophysica acta 2002;1597(2):260-70.
2002: Sivaraman J; Sauvé Véronique; Larocque Robert; Stura Enrico A; Schrag Joseph D; Cygler Miroslaw; Matte Allan
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nature structural biology 2002;9(5):353-8.
2002: Barbosa João A R G; Sivaraman J; Li Yunge; Larocque Robert; Matte Allan; Schrag Joseph D; Cygler Miroslaw
Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):1859-64.
2002: Cygler Miroslaw; Grochulski Pawel; Blanchard Helen
Crystallization and structural details of Ca(2+)-induced conformational changes in the EF-hand domain VI of calpain.
Methods in molecular biology (Clifton, N.J.) 2002;172():243-60.
2001: Jia J; Borregaard N; Lollike K; Cygler M
Structure of Ca(2+)-loaded human grancalcin.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 12):1843-9.
2001: Schrag J D; Bergeron J J; Li Y; Borisova S; Hahn M; Thomas D Y; Cygler M
The Structure of calnexin, an ER chaperone involved in quality control of protein folding.
Molecular cell 2001;8(3):633-44.
2001: Sivaraman J; Li Y; Larocque R; Schrag J D; Cygler M; Matte A
Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
Journal of molecular biology 2001;311(4):761-76.
2001: Schrag J D; Huang W; Sivaraman J; Smith C; Plamondon J; Larocque R; Matte A; Cygler M
The crystal structure of Escherichia coli MoeA, a protein from the molybdopterin synthesis pathway.
Journal of molecular biology 2001;310(2):419-31.
2001: Schmidt A; Sivaraman J; Li Y; Larocque R; Barbosa J A; Smith C; Matte A; Schrag J D; Cygler M
Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.
Biochemistry 2001;40(17):5151-60.
2001: Jia J; Tarabykina S; Hansen C; Berchtold M; Cygler M
Structure of apoptosis-linked protein ALG-2: insights into Ca2+-induced changes in penta-EF-hand proteins.
Structure (London, England : 1993) 2001;9(4):267-75.
2001: Huang W; Boju L; Tkalec L; Su H; Yang H O; Gunay N S; Linhardt R J; Kim Y S; Matte A; Cygler M
Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
Biochemistry 2001;40(8):2359-72.
2000: Huang W; Matte A; Suzuki S; Sugiura N; Miyazono H; Cygler M
Crystallization and preliminary X-ray analysis of chondroitin sulfate ABC lyases I and II from Proteus vulgaris.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 7):904-6.
2000: Jia J; Han Q; Borregaard N; Lollike K; Cygler M
Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.
Journal of molecular biology 2000;300(5):1271-81.
2000: Pawelek P D; Allaire M; Cygler M; MacKenzie R E
Channeling efficiency in the bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase domain: the effects of site-directed mutagenesis of NADP binding residues.
Biochimica et biophysica acta 2000;1479(1-2):59-68.
2000: Han Q; Jia J; Li Y; Lollike K; Cygler M
Crystallization and preliminary X-ray analysis of human grancalcin, a novel cytosolic Ca2+-binding protein present in leukocytes.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 6):772-4.
2000: Schmidt A; Wu H; MacKenzie R E; Chen V J; Bewly J R; Ray J E; Toth J E; Cygler M
Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry 2000;39(21):6325-35.
2000: Dutt P; Arthur J S; Grochulski P; Cygler M; Elce J S
Roles of individual EF-hands in the activation of m-calpain by calcium.
The Biochemical journal 2000;348 Pt 1():37-43.
2000: Slon-Usakiewicz J J; Sivaraman J; Li Y; Cygler M; Konishi Y
Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Biochemistry 2000;39(9):2384-91.
2000: Sivaraman J; Nägler D K; Zhang R; Ménard R; Cygler M
Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
Journal of molecular biology 2000;295(4):939-51.
1999: Huang W; Matte A; Li Y; Kim Y S; Linhardt R J; Su H; Cygler M
Crystal structure of chondroitinase B from Flavobacterium heparinum and its complex with a disaccharide product at 1.7 A resolution.
Journal of molecular biology 1999;294(5):1257-69.
1999: Cygler M; Schrag J D
Structure and conformational flexibility of Candida rugosa lipase.
Biochimica et biophysica acta 1999;1441(2-3):205-14.
1999: Féthière J; Eggimann B; Cygler M
Crystal structure of chondroitin AC lyase, a representative of a family of glycosaminoglycan degrading enzymes.
Journal of molecular biology 1999;288(4):635-47.
1999: Li Y; Matte A; Su H; Cygler M
Crystallization and preliminary X-ray analysis of chondroitinase B from Flavobacterium heparinum.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 5):1055-7.
1999: Quraishi O; Nägler D K; Fox T; Sivaraman J; Cygler M; Mort J S; Storer A C
The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide.
Biochemistry 1999;38(16):5017-23.
1999: Sivaraman J; Lalumière M; Ménard R; Cygler M
Crystal structure of wild-type human procathepsin K.
Protein science : a publication of the Protein Society 1999;8(2):283-90.
1998: Hahn M; Borisova S; Schrag J D; Tessier D C; Zapun A; Tom R; Kamen A A; Bergeron J J; Thomas D Y; Cygler M
Identification and crystallization of a protease-resistant core of calnexin that retains biological activity.
Journal of structural biology 1998;123(3):260-4.
1998: Féthière J; Shilton B H; Li Y; Allaire M; Laliberté M; Eggimann B; Cygler M
Crystallization and preliminary analysis of chondroitinase AC from Flavobacterium heparinum.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 2):279-80.
1998: Allaire M; Li Y; MacKenzie R E; Cygler M
The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution.
Structure (London, England : 1993) 1998;6(2):173-82.
1997: Holmquist M; Tessier D C; Cygler M
Identification of residues essential for differential fatty acyl specificity of Geotrichum candidum lipases I and II.
Biochemistry 1997;36(48):15019-25.
1997: Cygler M; Mort J S
Proregion structure of members of the papain superfamily. Mode of inhibition of enzymatic activity.
Biochimie 1997;79(11):645-52.
1997: Slon-Usakiewicz J J; Purisima E; Tsuda Y; Sulea T; Pedyczak A; Féthière J; Cygler M; Konishi Y
Nonpolar interactions of thrombin S' subsites with its bivalent inhibitor: methyl scan of the inhibitor linker.
Biochemistry 1997;36(44):13494-502.
1997: Holmquist M; Tessier D C; Cygler M
High-level production of recombinant Geotrichum candidum lipases in yeast Pichia pastoris.
Protein expression and purification 1997;11(1):35-40.
1997: Coulombe R; Cygler M
Procedure to calculate the molecular envelope from a partial model.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 4):426-33.
1997: Blanchard H; Grochulski P; Li Y; Arthur J S; Davies P L; Elce J S; Cygler M
Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.
Nature structural biology 1997;4(7):532-8.
1997: Shilton B H; Thomas D Y; Cygler M
Crystal structure of Kex1deltap, a prohormone-processing carboxypeptidase from Saccharomyces cerevisiae,.
Biochemistry 1997;36(29):9002-12.
1997: Schwartz J L; Juteau M; Grochulski P; Cygler M; Préfontaine G; Brousseau R; Masson L
Restriction of intramolecular movements within the Cry1Aa toxin molecule of Bacillus thuringiensis through disulfide bond engineering.
FEBS letters 1997;410(2-3):397-402.
1997: Schrag J D; Li Y; Cygler M; Lang D; Burgdorf T; Hecht H J; Schmid R; Schomburg D; Rydel T J; Oliver J D; Strickland L C; Dunaway C M; Larson S B; Day J; McPherson A
The open conformation of a Pseudomonas lipase.
Structure (London, England : 1993) 1997;5(2):187-202.
1997: Schrag J D; Cygler M
Lipases and alpha/beta hydrolase fold.
Methods in enzymology 1997;284():85-107.
1997: Cygler M; Schrag J D
Structure as basis for understanding interfacial properties of lipases.
Methods in enzymology 1997;284():3-27.
1996: Allaire M; Li Y; Mejia N R; Pelletier J N; MacKenzie R E; Cygler M
Crystallization of the bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase domain of the human trifunctional enzyme.
Proteins 1996;26(4):479-80.
1996: Coulombe R; Grochulski P; Sivaraman J; Ménard R; Mort J S; Cygler M
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
The EMBO journal 1996;15(20):5492-503.
1996: Sivaraman J; Coloumbe R; Magny M C; Mason P; Mort J S; Cygler M
Crystallization of rat procathepsin B.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 4):874-5.
1996: Coulombe R; Li Y; Takebe S; Ménard R; Mason P; Mort J S; Cygler M
Crystallization and preliminary X-ray diffraction studies of human procathepsin L.
Proteins 1996;25(3):398-400.
1996: Féthière J; Tsuda Y; Coulombe R; Konishi Y; Cygler M
Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
Protein science : a publication of the Protein Society 1996;5(6):1174-83.
1996: Cygler M; Sivaraman J; Grochulski P; Coulombe R; Storer A C; Mort J S
Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion.
Structure (London, England : 1993) 1996;4(4):405-16.
1996: Blanchard H; Li Y; Cygler M; Kay C M; Simon J; Arthur C; Davies P L; Elce J S
Ca(2+)-binding domain VI of rat calpain is a homodimer in solution: hydrodynamic, crystallization and preliminary X-ray diffraction studies.
Protein science : a publication of the Protein Society 1996;5(3):535-7.
1996: Shilton B H; Li Y; Tessier D; Thomas D Y; Cygler M
Crystallization of a soluble form of the Kex1p serine carboxypeptidase from Saccharomyces cerevisiae.
Protein science : a publication of the Protein Society 1996;5(2):395-7.
1995: Grochulski P; Masson L; Borisova S; Pusztai-Carey M; Schwartz J L; Brousseau R; Cygler M
Bacillus thuringiensis CryIA(a) insecticidal toxin: crystal structure and channel formation.
Journal of molecular biology 1995;254(3):447-64.
1995: Rehse P H; Steinmetzer T; Li Y; Konishi Y; Cygler M
Crystal structure of a peptidyl pyridinium methyl ketone inhibitor with thrombin.
Biochemistry 1995;34(36):11537-44.
1995: Schrag J D; Vernet T; Laramée L; Thomas D Y; Recktenwald A; Okoniewska M; Ziomek E; Cygler M
Redesigning the active site of Geotrichum candidum lipase.
Protein engineering 1995;8(8):835-42.
1995: Bertolini M C; Schrag J D; Cygler M; Ziomek E; Thomas D Y; Vernet T
Expression and characterization of Geotrichum candidum lipase I gene. Comparison of specificity profile with lipase II.
European journal of biochemistry / FEBS 1995;228(3):863-9.
1995: Cygler M; Grochulski P; Schrag J D
Structural determinants defining common stereoselectivity of lipases toward secondary alcohols.
Canadian journal of microbiology 1995;41 Suppl 1():289-96.
1994: Tsuda Y; Cygler M; Gibbs B F; Pedyczak A; Féthière J; Yue S Y; Konishi Y
Design of potent bivalent thrombin inhibitors based on hirudin sequence: incorporation of nonsubstrate-type active site inhibitors.
Biochemistry 1994;33(48):14443-51.
1994: Borisova S; Grochulski P; van Faassen H; Pusztai-Carey M; Masson L; Cygler M
Crystallization and preliminary X-ray diffraction studies of the lepidopteran-specific insecticidal crystal protein CrylA(a).
Journal of molecular biology 1994;243(3):530-2.
1994: Pokkuluri P R; Bouthillier F; Li Y; Kuderova A; Lee J; Cygler M
Preparation, characterization and crystallization of an antibody Fab fragment that recognizes RNA. Crystal structures of native Fab and three Fab-mononucleotide complexes.
Journal of molecular biology 1994;243(2):283-97.
1994: Zdanov A; Li Y; Bundle D R; Deng S J; MacKenzie C R; Narang S A; Young N M; Cygler M
Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6423-7.
1994: Bundle D R; Baumann H; Brisson J R; Gagné S M; Zdanov A; Cygler M
Solution structure of a trisaccharide-antibody complex: comparison of NMR measurements with a crystal structure.
Biochemistry 1994;33(17):5183-92.
1994: Grochulski P; Bouthillier F; Kazlauskas R J; Serreqi A N; Schrag J D; Ziomek E; Cygler M
Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase.
Biochemistry 1994;33(12):3494-500.
1994: Bertolini M C; Laramée L; Thomas D Y; Cygler M; Schrag J D; Vernet T
Polymorphism in the lipase genes of Geotrichum candidum strains.
European journal of biochemistry / FEBS 1994;219(1-2):119-25.
1994: Grochulski P; Li Y; Schrag J D; Cygler M
Two conformational states of Candida rugosa lipase.
Protein science : a publication of the Protein Society 1994;3(1):82-91.
1994: Cygler M
Recognition of carbohydrates by antibodies.
Research in immunology 1994;145(1):36-40.
1993: Vernet T; Ziomek E; Recktenwald A; Schrag J D; de Montigny C; Tessier D C; Thomas D Y; Cygler M
Cloning and expression of Geotrichum candidum lipase II gene in yeast. Probing of the enzyme active site by site-directed mutagenesis.
The Journal of biological chemistry 1993;268(35):26212-9.
1993: Zdanov A; Wu S; DiMaio J; Konishi Y; Li Y; Wu X; Edwards B F; Martin P D; Cygler M
Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6.
Proteins 1993;17(3):252-65.
1993: Grochulski P; Li Y; Schrag J D; Bouthillier F; Smith P; Harrison D; Rubin B; Cygler M
Insights into interfacial activation from an open structure of Candida rugosa lipase.
The Journal of biological chemistry 1993;268(17):12843-7.
1993: Cygler M; Wu S; Zdanov A; Bundle D R; Rose D R
Recognition of a carbohydrate antigenic determinant of Salmonella by an antibody.
Biochemical Society transactions 1993;21(2):437-41.
1993: Szewczuk Z; Gibbs B F; Yue S Y; Purisima E; Zdanov A; Cygler M; Konishi Y
Design of a linker for trivalent thrombin inhibitors: interaction of the main chain of the linker with thrombin.
Biochemistry 1993;32(13):3396-404.
1993: Schrag J D; Cygler M
1.8 A refined structure of the lipase from Geotrichum candidum.
Journal of molecular biology 1993;230(2):575-91.
1993: Cygler M; Schrag J D; Sussman J L; Harel M; Silman I; Gentry M K; Doctor B P
Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins.
Protein science : a publication of the Protein Society 1993;2(3):366-82.
1993: Wu S; Cygler M
Conformation of complementarity determining region L1 loop in murine IgG lambda light chain extends the repertoire of canonical forms.
Journal of molecular biology 1993;229(3):597-601.
1992: Ollis D L; Cheah E; Cygler M; Dijkstra B; Frolow F; Franken S M; Harel M; Remington S J; Silman I; Schrag J
The alpha/beta hydrolase fold.
Protein engineering 1992;5(3):197-211.
1992: Schrag J D; Winkler F K; Cygler M
Pancreatic lipases: evolutionary intermediates in a positional change of catalytic carboxylates?
The Journal of biological chemistry 1992;267(7):4300-3.
1992: Cygler M; Schrag J D; Ergan F
Advances in structural understanding of lipases.
Biotechnology & genetic engineering reviews 1992;10():143-84.
1991: Schrag J D; Li Y; Wu S; Cygler M
Multiple crystal forms of lipases from Geotrichum candidum.
Journal of molecular biology 1991;220(3):541-3.
1991: Cygler M; Rose D R; Bundle D R
Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.
Science (New York, N.Y.) 1991;253(5018):442-5.
1991: Schrag J D; Li Y G; Wu S; Cygler M
Ser-His-Glu triad forms the catalytic site of the lipase from Geotrichum candidum.
Nature 1991;351(6329):761-4.
1990: Rose D R; Cygler M; To R J; Przybylska M; Sinnott B; Bundle D R
Preliminary crystal structure analysis of an Fab specific for a Salmonella O-polysaccharide antigen.
Journal of molecular biology 1990;215(4):489-92.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Miroslaw Cygler

Research Profile (preview)

Procedures

Concepts & Ideas

Chemicals & Drugs

Genes & Molecular Sequences

Phenomena

Living Beings

Physiology

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Miroslaw Cygler (preview)

All Publications