Alicia Alonso

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Ibarguren Maitane; Bomans Paul H H; Frederik Peter M; Stonehouse Martin; Vasil Adriana I; Vasil Michael L; Alonso Alicia; Goñi Félix M
End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.
Montes L-Ruth; Ahyayauch Hasna; Ibarguren Maitane; Sot Jesus; Alonso Alicia; Bagatolli Luis A; Goñi Felix M
Electroformation of giant unilamellar vesicles from native membranes and organic lipid mixtures for the study of lipid domains under physiological ionic-strength conditions.
Busto Jon V; Fanani María Laura; De Tullio Luisina; Sot Jesús; Maggio Bruno; Goñi Félix M; Alonso Alicia
Coexistence of immiscible mixtures of palmitoylsphingomyelin and palmitoylceramide in monolayers and bilayers.

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2010: Ibarguren Maitane; Bomans Paul H H; Frederik Peter M; Stonehouse Martin; Vasil Adriana I; Vasil Michael L; Alonso Alicia; Goñi Félix M
End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.
Biochimica et biophysica acta 2010;1798(1):59-64.
2010: Montes L-Ruth; Ahyayauch Hasna; Ibarguren Maitane; Sot Jesus; Alonso Alicia; Bagatolli Luis A; Goñi Felix M
Electroformation of giant unilamellar vesicles from native membranes and organic lipid mixtures for the study of lipid domains under physiological ionic-strength conditions.
Methods in molecular biology (Clifton, N.J.) 2010;606():105-14.
2009: Busto Jon V; Fanani María Laura; De Tullio Luisina; Sot Jesús; Maggio Bruno; Goñi Félix M; Alonso Alicia
Coexistence of immiscible mixtures of palmitoylsphingomyelin and palmitoylceramide in monolayers and bilayers.
Biophysical journal 2009;97(10):2717-26.
2009: García-Pacios Marcos; Collado M Isabel; Busto Jon V; Sot Jesús; Alonso Alicia; Arrondo José-Luis R; Goñi Félix M
Sphingosine-1-phosphate as an amphipathic metabolite: its properties in aqueous and membrane environments.
Biophysical journal 2009;97(5):1398-407.
2009: Urbina Patricia; Flores-Díaz Marietta; Alape-Girón Alberto; Alonso Alicia; Goni Félix M
Phospholipase C and sphingomyelinase activities of the Clostridium perfringens alpha-toxin.
Chemistry and physics of lipids 2009;159(1):51-7.
2009: Ahyayauch Hasna; Arana Gorka; Sot Jesús; Alonso Alicia; Goñi Félix M
Calcium inhibits diacylglycerol uptake by serum albumin.
Biochimica et biophysica acta 2009;1788(3):701-7.
2009: Goñi Félix M; Alonso Alicia
Effects of ceramide and other simple sphingolipids on membrane lateral structure.
Biochimica et biophysica acta 2009;1788(1):169-77.
2009: Contreras F-Xabier; Villar Ana-Victoria; Alonso Alicia; Goñi Félix M
Ceramide-induced transbilayer (flip-flop) lipid movement in membranes.
Methods in molecular biology (Clifton, N.J.) 2009;462():155-65.
2008: Busto Jon V; Del Canto-Jañez Esther; Goñi Félix M; Mollinedo Faustino; Alonso Alicia
Combination of the anti-tumour cell ether lipid edelfosine with sterols abolishes haemolytic side effects of the drug.
Journal of chemical biology 2008;1(1-4):89-94.
2008: Goñi Félix M; Alonso Alicia; Bagatolli Luis A; Brown Rhoderick E; Marsh Derek; Prieto Manuel; Thewalt Jenifer L
Phase diagrams of lipid mixtures relevant to the study of membrane rafts.
Biochimica et biophysica acta 2008;1781(11-12):665-84.
2008: Montes L-Ruth; López David J; Sot Jesús; Bagatolli Luis A; Stonehouse Martin J; Vasil Michael L; Wu Bill X; Hannun Yusuf A; Goñi Félix M; Alonso Alicia
Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold hemolysis.
Biochemistry 2008;47(43):11222-30.
2008: Sot Jesús; Ibarguren Maitane; Busto Jon V; Montes L-Ruth; Goñi Félix M; Alonso Alicia
Cholesterol displacement by ceramide in sphingomyelin-containing liquid-ordered domains, and generation of gel regions in giant lipidic vesicles.
FEBS letters 2008;582(21-22):3230-6.
2008: Kooijman Edgar E; Sot Jesús; Montes L-Ruth; Alonso Alicia; Gericke Arne; de Kruijff Ben; Kumar Satyendra; Goñi Felix M
Membrane organization and ionization behavior of the minor but crucial lipid ceramide-1-phosphate.
Biophysical journal 2008;94(11):4320-30.
2007: Montes L-Ruth; Alonso Alicia; Goñi Felix M; Bagatolli Luis A
Giant unilamellar vesicles electroformed from native membranes and organic lipid mixtures under physiological conditions.
Biophysical journal 2007;93(10):3548-54.
2007: Arnulphi Cristina; Sot Jesús; García-Pacios Marcos; Arrondo José-Luis R; Alonso Alicia; Goñi Félix M
Triton X-100 partitioning into sphingomyelin bilayers at subsolubilizing detergent concentrations: effect of lipid phase and a comparison with dipalmitoylphosphatidylcholine.
Biophysical journal 2007;93(10):3504-14.
2007: Montes L-Ruth; Ibarguren Maitane; Goñi Félix M; Stonehouse Martin; Vasil Michael L; Alonso Alicia
Leakage-free membrane fusion induced by the hydrolytic activity of PlcHR(2), a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.
Biochimica et biophysica acta 2007;1768(10):2365-72.
2007: Busto Jon V; Sot Jesús; Goñi Félix M; Mollinedo Faustino; Alonso Alicia
Surface-active properties of the antitumour ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (edelfosine).
Biochimica et biophysica acta 2007;1768(7):1855-60.
2006: Goñi Félix M; Alonso Alicia
Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids.
Biochimica et biophysica acta 2006;1758(12):1902-21.
2006: Contreras F-Xabier; Sot Jesús; Alonso Alicia; Goñi Félix M
Sphingosine increases the permeability of model and cell membranes.
Biophysical journal 2006;90(11):4085-92.
2006: Ahyayauch Hasna; Larijani Banafshe; Alonso Alicia; Goñi Félix M
Detergent solubilization of phosphatidylcholine bilayers in the fluid state: influence of the acyl chain structure.
Biochimica et biophysica acta 2006;1758(2):190-6.
2006: Urbina Patricia; Alonso Alicia; Contreras F-Xabier; Goñi Félix M; López David J; Montes L-Ruth; Sot Jesús
Alkanes are not innocuous vehicles for hydrophobic reagents in membrane studies.
Chemistry and physics of lipids 2006;139(2):107-14.
2006: Sot Jesús; Bagatolli Luis A; Goñi Félix M; Alonso Alicia
Detergent-resistant, ceramide-enriched domains in sphingomyelin/ceramide bilayers.
Biophysical journal 2006;90(3):903-14.
2005: Ahyayauch Hasna; Villar Ana V; Alonso Alicia; Goñi Félix M
Modulation of PI-specific phospholipase C by membrane curvature and molecular order.
Biochemistry 2005;44(34):11592-600.
2005: Sot Jesús; Goñi Félix M; Alonso Alicia
Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides.
Biochimica et biophysica acta 2005;1711(1):12-9.
2005: Sot Jesús; Aranda Francisco J; Collado M-Isabel; Goñi Félix M; Alonso Alicia
Different effects of long- and short-chain ceramides on the gel-fluid and lamellar-hexagonal transitions of phospholipids: a calorimetric, NMR, and x-ray diffraction study.
Biophysical journal 2005;88(5):3368-80.
2005: Collado M Isabel; Goñi Félix M; Alonso Alicia; Marsh Derek
Domain formation in sphingomyelin/cholesterol mixed membranes studied by spin-label electron spin resonance spectroscopy.
Biochemistry 2005;44(12):4911-8.
2005: Jones David R; Pañeda Covadonga; Villar Ana Victoria; Alonso Alicia; Goñi Félix M; Bütikofer Peter; Brodbeck Urs; Shepherd Peter R; Varela-Nieto Isabel
Phosphorylation of glycosyl-phosphatidylinositol by phosphatidylinositol 3-kinase changes its properties as a substrate for phospholipases.
FEBS letters 2005;579(1):59-65.
2005: Contreras F-Xabier; Basañez Gorka; Alonso Alicia; Herrmann Andreas; Goñi Félix M
Asymmetric addition of ceramides but not dihydroceramides promotes transbilayer (flip-flop) lipid motion in membranes.
Biophysical journal 2005;88(1):348-59.
2005: Goñi Félix M; Contreras F-Xabier; Montes L-Ruth; Sot Jesús; Alonso Alicia
Biophysics (and sociology) of ceramides.
Biochemical Society symposium 2005;(72):177-88.
2004: Contreras F-X; Sot J; Ruiz-Argüello M-B; Alonso A; Goñi F M
Cholesterol modulation of sphingomyelinase activity at physiological temperatures.
Chemistry and physics of lipids 2004;130(2):127-34.
2004: Montes L-Ruth; Goñi Félix M; Johnston Norah C; Goldfine Howard; Alonso Alicia
Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes.
Biochemistry 2004;43(12):3688-95.
2003: Contreras F-Xabier; Villar Ana-Victoria; Alonso Alicia; Kolesnick Richard N; Goñi Félix M
Sphingomyelinase activity causes transbilayer lipid translocation in model and cell membranes.
The Journal of biological chemistry 2003;278(39):37169-74.
2003: Goñi Félix M; Villar Ana V; Nieva José L; Alonso Alicia
Interaction of phospholipases C and sphingomyelinase with liposomes.
Methods in enzymology 2003;372():3-19.
2002: Ahyayauch Hasna; Requero M Asun; Alonso Alicia; Bennouna Mohammed; Goñi Félix M
Surfactant effects of chlorpromazine and imipramine on lipid bilayers containing sphingomyelin and cholesterol.
Journal of colloid and interface science 2002;256(2):284-9.
2002: Goñi Félix M; Alonso Alicia
Sphingomyelinases: enzymology and membrane activity.
FEBS letters 2002;531(1):38-46.
2002: Montes L Ruth; Ruiz-Argüello M Begoña; Goñi Félix M; Alonso Alicia
Membrane restructuring via ceramide results in enhanced solute efflux.
The Journal of biological chemistry 2002;277(14):11788-94.
2002: Ruiz-Argüello M Begoña; Veiga M Pilar; Arrondo José L R; Goñi Félix M; Alonso Alicia
Sphingomyelinase cleavage of sphingomyelin in pure and mixed lipid membranes. Influence of the physical state of the sphingolipid.
Chemistry and physics of lipids 2002;114(1):11-20.
2001: Pañeda C; Villar A V; Alonso A; Goñi F M; Varela F; Brodbeck U; León Y; Varela-Nieto I; Jones D R
Purification and characterization of insulin-mimetic inositol phosphoglycan-like molecules from grass pea (Lathyrus sativus) seeds.
Molecular medicine (Cambridge, Mass.) 2001;7(7):454-60.
2001: Villar A V; Goñi F M; Alonso A
Diacylglycerol effects on phosphatidylinositol-specific phospholipase C activity and vesicle fusion.
FEBS letters 2001;494(1-2):117-20.
2000: Goñi F M; Alonso A
Spectroscopic techniques in the study of membrane solubilization, reconstitution and permeabilization by detergents.
Biochimica et biophysica acta 2000;1508(1-2):51-68.
2000: Villar A V; Alonso A; Goñi F M
Leaky vesicle fusion induced by phosphatidylinositol-specific phospholipase C: observation of mixing of vesicular inner monolayers.
Biochemistry 2000;39(46):14012-8.
1999: Villar A V; Alonso A; Pañeda C; Varela-Nieto I; Brodbeck U; Goñi F M
Towards the in vitro reconstitution of caveolae. Asymmetric incorporation of glycosylphosphatidylinositol (GPI) and gangliosides into liposomal membranes.
FEBS letters 1999;457(1):71-4.
1999: Goñi F M; Alonso A
Structure and functional properties of diacylglycerols in membranes.
Progress in lipid research 1999;38(1):1-48.
1998: Ruiz-Argüello M B; Goñi F M; Alonso A
Vesicle membrane fusion induced by the concerted activities of sphingomyelinase and phospholipase C.
The Journal of biological chemistry 1998;273(36):22977-82.
1998: Villar A V; Goñi F M; Alonso A; Jones D R; León Y; Varela-Nieto I
Phospholipase cleavage of glycosylphosphatidylinositol reconstituted in liposomal membranes.
FEBS letters 1998;432(3):150-4.
1998: Ruiz-Argüello M B; Goñi F M; Alonso A
Phospholipase C hydrolysis of phospholipids in bilayers of mixed lipid compositions.
Biochemistry 1998;37(33):11621-8.
1998: Basáñez G; Goñi F M; Alonso A
Effect of single chain lipids on phospholipase C-promoted vesicle fusion. A test for the stalk hypothesis of membrane fusion.
Biochemistry 1998;37(11):3901-8.
1998: Goñi F M; Basáñez G; Begoña Ruiz-Argüello M; Alonso A
Interfacial enzyme activation, non-lamellar phase formation and membrane fusion. Is there a conducting thread?
Faraday discussions 1998;(111):55-68; discussion 69-78.
1997: Basáñez G; Goñi F M; Alonso A
Poly(ethylene glycol)-lipid conjugates inhibit phospholipase C-induced lipid hydrolysis, liposome aggregation and fusion through independent mechanisms.
FEBS letters 1997;411(2-3):281-6.
1997: Basáñez G; Ruiz-Argüello M B; Alonso A; Goñi F M; Karlsson G; Edwards K
Morphological changes induced by phospholipase C and by sphingomyelinase on large unilamellar vesicles: a cryo-transmission electron microscopy study of liposome fusion.
Biophysical journal 1997;72(6):2630-7.
1996: Basáñez G; Nieva J L; Goñi F M; Alonso A
Origin of the lag period in the phospholipase C cleavage of phospholipids in membranes. Concomitant vesicle aggregation and enzyme activation.
Biochemistry 1996;35(48):15183-7.
1996: Ruiz-Argüello M B; Basáñez G; Goñi F M; Alonso A
Different effects of enzyme-generated ceramides and diacylglycerols in phospholipid membrane fusion and leakage.
The Journal of biological chemistry 1996;271(43):26616-21.
1996: Basáñez G; Fidelio G D; Goñi F M; Maggio B; Alonso A
Dual inhibitory effect of gangliosides on phospholipase C-promoted fusion of lipidic vesicles.
Biochemistry 1996;35(23):7506-13.
1995: Requero M A; Goñi F M; Alonso A
The membrane-perturbing properties of palmitoyl-coenzyme A and palmitoylcarnitine. A comparative study.
Biochemistry 1995;34(33):10400-5.
1995: Nieva J L; Alonso A; Basáñez G; Goñi F M; Gulik A; Vargas R; Luzzati V
Topological properties of two cubic phases of a phospholipid:cholesterol:diacylglycerol aqueous system and their possible implications in the phospholipase C-induced liposome fusion.
FEBS letters 1995;368(1):143-7.
1995: Requero M A; González M; Goñi F M; Alonso A; Fidelio G
Differential penetration of fatty acyl-coenzyme A and fatty acylcarnitines into phospholipid monolayers.
FEBS letters 1995;357(1):75-8.
1994: Goñi F M; Nieva J L; Basañez G; Fidelio G; Alonso A
Phospholipase-C-promoted liposome fusion.
Biochemical Society transactions 1994;22(3):839-44.

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