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Ge Dai

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Pengcheng P Shao; McHardy M Smith; Shu-Yu Sun; Andrew M Swensen; Deepu J Varughese; Vivien A Warren; Feng Ye; Catherine Abbadie; Randal M Bugianesi; Prasun K Chakravarty; Ge Dai; Maria L Garcia; Mitchell Green; Rodolfo J Haedo; James B Herrington; Nina Jochnowitz; Gregory J Kaczorowski; Xiaohua Li; Kathryn A Lyons; Erin McGowan; Owen B McManus; Shruti Mistry; Joseph L Duffy
Aminopiperidine sulfonamide Cav2.2 channel inhibitors for the treatment of chronic pain.
Andrew M Swensen; Vivien A Warren; David Parker; Kevin S Ratliff; McHardy Smith; Terrance P Snutch; Stephen P Arneric; Randal M Bugianesi; Ge Dai; Joseph L Duffy; Cyrus Eduljee; Rodolfo J Haedo; James Herrington; Scott B Hoyt; Gregory J Kaczorowski; Clare London; Owen B McManus
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
Catherine Abbadie; Owen B McManus; Shu-Yu Sun; Randal M Bugianesi; Ge Dai; Rodolfo J Haedo; James B Herrington; Gregory J Kaczorowski; McHardy Smith; Andrew M Swensen; Vivien A Warren; Brande Williams; Stephen P Arneric; Cyrus Eduljee; Terrance P Snutch; Elizabeth W Tringham; Nina Jochnowitz; Annie Liang; D Euan MacIntyre; Erin McGowan; Shruti Mistry; Valerie V White; Scott B Hoyt; Clare London; Kathryn A Lyons; Patricia B Bunting; Sylvia Volksdorf; Joseph L Duffy
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.

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All Publications

2012: Pengcheng P Shao; McHardy M Smith; Shu-Yu Sun; Andrew M Swensen; Deepu J Varughese; Vivien A Warren; Feng Ye; Catherine Abbadie; Randal M Bugianesi; Prasun K Chakravarty; Ge Dai; Maria L Garcia; Mitchell Green; Rodolfo J Haedo; James B Herrington; Nina Jochnowitz; Gregory J Kaczorowski; Xiaohua Li; Kathryn A Lyons; Erin McGowan; Owen B McManus; Shruti Mistry; Joseph L Duffy
Aminopiperidine sulfonamide Cav2.2 channel inhibitors for the treatment of chronic pain.
Journal of medicinal chemistry 2012;55(22):9847-55.
2012: Andrew M Swensen; Vivien A Warren; David Parker; Kevin S Ratliff; McHardy Smith; Terrance P Snutch; Stephen P Arneric; Randal M Bugianesi; Ge Dai; Joseph L Duffy; Cyrus Eduljee; Rodolfo J Haedo; James Herrington; Scott B Hoyt; Gregory J Kaczorowski; Clare London; Owen B McManus
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
Molecular pharmacology 2012;81(3):488-97.
2010: Catherine Abbadie; Owen B McManus; Shu-Yu Sun; Randal M Bugianesi; Ge Dai; Rodolfo J Haedo; James B Herrington; Gregory J Kaczorowski; McHardy Smith; Andrew M Swensen; Vivien A Warren; Brande Williams; Stephen P Arneric; Cyrus Eduljee; Terrance P Snutch; Elizabeth W Tringham; Nina Jochnowitz; Annie Liang; D Euan MacIntyre; Erin McGowan; Shruti Mistry; Valerie V White; Scott B Hoyt; Clare London; Kathryn A Lyons; Patricia B Bunting; Sylvia Volksdorf; Joseph L Duffy
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
The Journal of pharmacology and experimental therapeutics 2010;334(2):545-55.
2009: Victor N Uebele; Cindy E Nuss; Steven V Fox; Susan L Garson; Razvan Cristescu; Scott M Doran; Richard L Kraus; vincent santarelli; Yuxing Li; James C Barrow; Zhi-Qiang Yang; Kelly-Ann S Schlegel; Kenneth E Rittle; Thomas S Reger; Rodney A Bednar; Wei Lemaire; Faith A Mullen; Jeanine E Ballard; Cuyue Tang; Ge Dai; Owen B McManus; Kenneth S Koblan; John Renger
Positive allosteric interaction of structurally diverse T-type calcium channel antagonists.
Cell biochemistry and biophysics 2009;55(2):81-93.
2008: Ge Dai; Rodolfo J Haedo; Vivien A Warren; Kevin S Ratliff; Randal M Bugianesi; Alison Rush; Mark E Williams; James Herrington; McHardy Smith; Owen B McManus; Andrew M Swensen
A high-throughput assay for evaluating state dependence and subtype selectivity of Cav2 calcium channel inhibitors.
Assay and drug development technologies 2008;6(2):195-212.
2005: william Schmalhofer; Manuel Sanchez; Ge Dai; Ashvin Dewan; Lorena Secades; Markus Hanner; Hans-Günther Knaus; Owen B McManus; Martin Kohler; Gregory J Kaczorowski; Maria L Garcia
Role of the C-terminus of the high-conductance calcium-activated potassium channel in channel structure and function.
Biochemistry 2005;44(30):10135-44.
2004: Birgit T Priest; Maria L Garcia; Richard E Middleton; Richard Brochu; Samantha Clark; Ge Dai; Ivy E Dick; John P Felix; Chou J Liu; Brita S Reiseter; william Schmalhofer; Pengcheng P Shao; Yui S Tang; Margaret Z Chou; Martin G Kohler; McHardy Smith; Vivien A Warren; Brande S Williams; charles cohen; William J Martin; Peter T Meinke; William H Parsons; Keith A Wafford; Gregory J Kaczorowski
A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model.
Biochemistry 2004;43(30):9866-76.
2003: Richard E Middleton; Manuel Sanchez; Ana-Rosa Linde; Randal M Bugianesi; Ge Dai; John P Felix; Sam L Koprak; Mary Jo Staruch; Marc Bruguera; Rachael Cox; Amrita Ghosh; Jeremy Hwang; Simmonette Jones; Martin Kohler; Robert S Slaughter; Owen B McManus; Gregory J Kaczorowski; Maria L Garcia
Substitution of a single residue in Stichodactyla helianthus peptide, ShK-Dap22, reveals a novel pharmacological profile.
Biochemistry 2003;42(46):13698-707.
2002: Richard E Middleton; Vivien A Warren; Richard L Kraus; Jeremy C Hwang; Chou J Liu; Ge Dai; Richard Brochu; Martin G Kohler; Ying-Duo Gao; Victor M Garsky; Michael J Bogusky; John T Mehl; charles cohen; McHardy Smith
Two tarantula peptides inhibit activation of multiple sodium channels.
Biochemistry 2002;41(50):14734-47.