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Kevin Dalby

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Publications

TOP 3
Jing Li; Swapna Moharana; Jake LeVieux; Kevin N Dalby; Brad Gilbreath; Tamer S Kaoud; Sean M Kerwin
A fluorescence-based assay for p38α recruitment site binders: identification of rooperol as a novel p38α kinase inhibitor.
Tamer S Kaoud; Kiyoun Lee; Shreya Mitra; Heekwang Park; Pengyu Ren; Yue Shi; Juliana M Taliaferro; Chun-Chia Tseng; Chunli Yan; Jiyong Hong; Jiney Jose; Kevin N Dalby
Manipulating JNK signaling with (--)-zuonin A.
Andrea Piserchio; Kevin N Dalby; Dana M Francis; Dorothy Koveal; Rebecca Page; Wolfgang Peti; Ranajeet Ghose
Docking interactions of hematopoietic tyrosine phosphatase with MAP kinases ERK2 and p38α.

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All Publications

2013: Jing Li; Swapna Moharana; Jake LeVieux; Kevin N Dalby; Brad Gilbreath; Tamer S Kaoud; Sean M Kerwin
A fluorescence-based assay for p38α recruitment site binders: identification of rooperol as a novel p38α kinase inhibitor.
Chembiochem : a European journal of chemical biology 2013;14(1):66-71.
2012: Tamer S Kaoud; Kiyoun Lee; Shreya Mitra; Heekwang Park; Pengyu Ren; Yue Shi; Juliana M Taliaferro; Chun-Chia Tseng; Chunli Yan; Jiyong Hong; Jiney Jose; Kevin N Dalby
Manipulating JNK signaling with (--)-zuonin A.
ACS chemical biology 2012;7(11):1873-83.
2012: Andrea Piserchio; Kevin N Dalby; Dana M Francis; Dorothy Koveal; Rebecca Page; Wolfgang Peti; Ranajeet Ghose
Docking interactions of hematopoietic tyrosine phosphatase with MAP kinases ERK2 and p38α.
Biochemistry 2012;51(41):8047-9.
2012: James A Madsen; Dmitrii E Makarov; Ryan R Cheng; Kevin N Dalby; Tamer S Kaoud; Jennifer S Brodbelt
Charge-site-dependent dissociation of hydrogen-rich radical peptide cations upon vacuum UV photoexcitation.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(17):5374-83.
2012: Clint D J Tavares; Mangalika Warthaka; Yan Zhang; Olga Abramczyk; Jennifer S Brodbelt; Ashwini K Devkota; Scarlett B Ferguson; Tamer S Kaoud; Karin M Keller; Kyle D Marshall; John P O'Brien; Bulent Ozpolat; Kevin S Shores; Kevin N Dalby
Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence.
Biochemistry 2012;51(11):2232-45.
2012: Ashwini K Devkota; Kivanc Gorgulu; Tamer S Kaoud; Kyle D Marshall; Bulent Ozpolat; Clint D J Tavares; Mangalika Warthaka; Olga Abramczyk; Kevin N Dalby
Investigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifact.
Biochemistry 2012;51(10):2100-12.
2012: Ibrahim Tekedereli; Ibrahim Sahin; Anil K Sood; Clint D J Tavares; S Neslihan Alpay; Zehra E Cobanoglu; Kevin N Dalby; Tamer S Kaoud; Gabriel Lopez-Berestein; Bulent Ozpolat
Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer.
PloS one 2012;7(7):e41171.
2012: Michael J Schnieders; Chunli Yan; Kevin N Dalby; Tamer S Kaoud; Pengyu Ren
Computational insights for the discovery of non-ATP competitive inhibitors of MAP kinases.
Current pharmaceutical design 2012;18(9):1173-85.
2011: Xuanzhi Zhan; Tamer S Kaoud; Kevin N Dalby; Vsevolod V Gurevich
Nonvisual arrestins function as simple scaffolds assembling the MKK4-JNK3α2 signaling complex.
Biochemistry 2011;50(48):10520-9.
2011: Sunbae Lee; Pengyu Ren; Mangalika Warthaka; Chunli Yan; Tamer S Kaoud; Kevin N Dalby
Examining docking interactions on ERK2 with modular peptide substrates.
Biochemistry 2011;50(44):9500-10.
2011: Olga Abramczyk; Ashwini K Devkota; Bulent Ozpolat; Austen F Riggs; Alexey G Ryazanov; Clint D J Tavares; Benjamin E Turk; Kevin N Dalby
Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli.
Protein expression and purification 2011;79(2):237-44.
2011: Tamer S Kaoud; Sunbae Lee; Klaus D Linse; Shreya Mitra; Juliana Taliaferro; Carla L Van Den Berg; Michael Cantrell; Kevin N Dalby
Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration.
ACS chemical biology 2011;6(6):658-66.
2011: Tianyi Yang; Johnny C Wu; Chunli Yan; Yuanfeng Wang; Ray Luo; Michael B Gonzales; Kevin N Dalby; Pengyu Ren
Virtual screening using molecular simulations.
Proteins 2011;79(6):1940-51.
2011: Tamer S Kaoud; Ashwini K Devkota; Richard Harris; Mitra S Rana; Olga Abramczyk; Mangalika Warthaka; Sunbae Lee; Mark E Girvin; Austen F Riggs; Kevin N Dalby
Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15.
Biochemistry 2011;50(21):4568-78.
2011: Andrea Piserchio; Mangalika Warthaka; Ashwini K Devkota; Tamer S Kaoud; Sunbae Lee; Olga Abramczyk; Pengyu Ren; Kevin N Dalby; Ranajeet Ghose
Solution NMR insights into docking interactions involving inactive ERK2.
Biochemistry 2011;50(18):3660-72.
2011: James A Madsen; Tamer S Kaoud; Kevin N Dalby; Jennifer S Brodbelt
193-nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization.
Proteomics 2011;11(7):1329-34.
2011: Chunli Yan; Tamer Kaoud; Sunbae Lee; Kevin N Dalby; Pengyu Ren
Understanding the specificity of a docking interaction between JNK1 and the scaffolding protein JIP1.
The journal of physical chemistry. B 2011;115(6):1491-502.
2011: Sunbae Lee; Mangalika Warthaka; Chunli Yan; Tamer S Kaoud; Andrea Piserchio; Ranajeet Ghose; Pengyu Ren; Kevin N Dalby
A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach.
PloS one 2011;6(4):e18594.
2010: Ashwini K Devkota; Tamer S Kaoud; Mangalika Warthaka; Kevin N Dalby
Fluorescent peptide assays for protein kinases.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2010;Chapter 18():Unit 18.17.
2010: Kari Callaway; William F Waas; Mark A Rainey; Pengyu Ren; Kevin N Dalby
Phosphorylation of the transcription factor Ets-1 by ERK2: rapid dissociation of ADP and phospho-Ets-1.
Biochemistry 2010;49(17):3619-30.
2009: Jing Li; Tamer S Kaoud; Christophe Laroche; Kevin N Dalby; Sean M Kerwin
Synthesis and biological evaluation of p38alpha kinase-targeting dialkynylimidazoles.
Bioorganic & medicinal chemistry letters 2009;19(22):6293-7.
2007: Kari Callaway; Olga Abramczyk; Lance Martin; Kevin N Dalby
The anti-apoptotic protein PEA-15 is a tight binding inhibitor of ERK1 and ERK2, which blocks docking interactions at the D-recruitment site.
Biochemistry 2007;46(32):9187-98.
2007: Olga Abramczyk; Mark A Rainey; Richard Barnes; Lance Martin; Kevin N Dalby
Expanding the repertoire of an ERK2 recruitment site: cysteine footprinting identifies the D-recruitment site as a mediator of Ets-1 binding.
Biochemistry 2007;46(32):9174-86.
2007: William F Waas; Kevin N Dalby
The expression and purification of the N-terminal activation domain of the transcription factor c-Myc: a model substrate for exploring ERK2 docking interactions.
Protein expression and purification 2007;53(1):80-6.
2007: Amrita Brahma; Kevin N Dalby
Regulation of protein phosphorylation within the MKK1-ERK2 complex by MP1 and the MP1*P14 heterodimer.
Archives of biochemistry and biophysics 2007;460(1):85-91.
2006: Kari Callaway; Mark A Rainey; Austen F Riggs; Olga Abramczyk; Kevin N Dalby
Properties and regulation of a transiently assembled ERK2.Ets-1 signaling complex.
Biochemistry 2006;45(46):13719-33.
2005: Kari Callaway; Mark A Rainey; Kevin N Dalby
Quantifying ERK2-protein interactions by fluorescence anisotropy: PEA-15 inhibits ERK2 by blocking the binding of DEJL domains.
Biochimica et biophysica acta 2005;1754(1-2):316-23.
2005: Anna E Szafranska; Kevin N Dalby
Kinetic mechanism for p38 MAP kinase alpha. A partial rapid-equilibrium random-order ternary-complex mechanism for the phosphorylation of a protein substrate.
The FEBS journal 2005;272(18):4631-45.
2005: Mark A Rainey; Kari Callaway; Richard Barnes; Brian Wilson; Kevin N Dalby
Proximity-induced catalysis by the protein kinase ERK2.
Journal of the American Chemical Society 2005;127(30):10494-5.
2005: Anna E Szafranska; Xuemei Luo; Kevin N Dalby
Following in vitro activation of mitogen-activated protein kinases by mass spectrometry and tryptic peptide analysis: purifying fully activated p38 mitogen-activated protein kinase alpha.
Analytical biochemistry 2005;336(1):1-10.
2004: William F Waas; Mark A Rainey; Anna E Szafranska; Kari Cox; Kevin N Dalby
A kinetic approach towards understanding substrate interactions and the catalytic mechanism of the serine/threonine protein kinase ERK2: identifying a potential regulatory role for divalent magnesium.
Biochimica et biophysica acta 2004;1697(1-2):81-7.
2004: Duane A Lewis; Kevin N Dalby; Creed W Abell
Conserved elements of the cytochrome P-450 superfamily found in monoamine oxidase B.
Neurotoxicology 2004;25(1-2):73-8.
2003: William F Waas; Mark A Rainey; Anna E Szafranska; Kevin N Dalby
Two rate-limiting steps in the kinetic mechanism of the serine/threonine specific protein kinase ERK2: a case of fast phosphorylation followed by fast product release.
Biochemistry 2003;42(42):12273-86.
2003: William F Waas; Kevin N Dalby
Physiological concentrations of divalent magnesium ion activate the serine/threonine specific protein kinase ERK2.
Biochemistry 2003;42(10):2960-70.
2002: William F Waas; Kevin N Dalby
Transient protein-protein interactions and a random-ordered kinetic mechanism for the phosphorylation of a transcription factor by extracellular-regulated protein kinase 2.
The Journal of biological chemistry 2002;277(15):12532-40.
2002: Robert E Hanes; Vincent M Lynch; Eric V Anslyn; Kevin N Dalby
Toward a stable hydroxyphosphorane.
Organic letters 2002;4(2):201-3.
2001: William F Waas; Kevin N Dalby
Purification of a model substrate for transcription factor phosphorylation by ERK2.
Protein expression and purification 2001;23(1):191-7.
2001: William F Waas; Herng-Hsiang Lo; Kevin N Dalby
The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase alpha. Implications for signal/response profiles of MAP kinase pathways.
The Journal of biological chemistry 2001;276(8):5676-84.