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Oya Alpar

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Objects

Microspheres

Living Beings

Procedures

Chemicals & Drugs

Concepts & Ideas

Particle Size

Devices

Drug Delivery Systems

Anatomy

Spleen

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Co-Publications
Name
21
Williamson, Diane
19
Eyles, Jim
12
Bramwell, Vincent
12
Somavarapu, Satyanarayana
8
Spiers, ID
4
Pandit, Sreenivas
4
Howard, Kenneth
3
Atuah, Kwame
3
Conway, Barbara
3
Moschos, Sterghios
3
Murdan, Sudaxshina
3
Singh, Jasvinder
2
Seymour, Leonard
2
Cevher, Erdal
2
Elvin, Stephen

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Publications

TOP 3
Kaye Richard S; Purewal Tol S; Alpar H Oya
Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies.
Dahlan Afendi; Alpar H Oya; Murdan Sudaxshina
An investigation into the combination of low frequency ultrasound and liposomes on skin permeability.
Uchida Masaki; Li Xiong Wei; Mertens Peter; Alpar H Oya
Transfection by particle bombardment: delivery of plasmid DNA into mammalian cells using gene gun.

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All Publications

2009: Kaye Richard S; Purewal Tol S; Alpar H Oya
Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies.
Journal of pharmaceutical sciences 2009;98(11):4055-68.
2009: Dahlan Afendi; Alpar H Oya; Murdan Sudaxshina
An investigation into the combination of low frequency ultrasound and liposomes on skin permeability.
International journal of pharmaceutics 2009;379(1):139-42.
2009: Uchida Masaki; Li Xiong Wei; Mertens Peter; Alpar H Oya
Transfection by particle bombardment: delivery of plasmid DNA into mammalian cells using gene gun.
Biochimica et biophysica acta 2009;1790(8):754-64.
2009: Katas Haliza; Cevher Erdal; Alpar H Oya
Preparation of polyethyleneimine incorporated poly(D,L-lactide-co-glycolide) nanoparticles by spontaneous emulsion diffusion method for small interfering RNA delivery.
International journal of pharmaceutics 2009;369(1-2):144-54.
2009: Florindo H F; Pandit S; Gonçalves L M D; Alpar H O; Almeida A J
New approach on the development of a mucosal vaccine against strangles: Systemic and mucosal immune responses in a mouse model.
Vaccine 2009;27(8):1230-41.
2009: Dahlan Afendi; Alpar H Oya; Stickings Paul; Sesardic Dorothea; Murdan Sudaxshina
Transcutaneous immunisation assisted by low-frequency ultrasound.
International journal of pharmaceutics 2009;368(1-2):123-8.
2008: Florindo H F; Pandit S; Gonçalves L M D; Alpar H O; Almeida A J
Streptococcus equi antigens adsorbed onto surface modified poly-epsilon-caprolactone microspheres induce humoral and cellular specific immune responses.
Vaccine 2008;26(33):4168-77.
2007: Pandit Sreenivas; Cevher Erdal; Zariwala Mohammed Gulrez; Somavarapu Satyanarayana; Alpar H Oya
Enhancement of immune response of HBsAg loaded poly (L-lactic acid) microspheres against hepatitis B through incorporation of alum and chitosan.
Journal of microencapsulation 2007;24(6):539-52.
2006: Katas Haliza; Alpar H Oya
Development and characterisation of chitosan nanoparticles for siRNA delivery.
Journal of controlled release : official journal of the Controlled Release Society 2006;115(2):216-25.
2006: Bridson R H; Santos R C D; Al-Duri B; McAllister S M; Robertson J; Alpar H O
The preparation of liposomes using compressed carbon dioxide: strategies, important considerations and comparison with conventional techniques.
The Journal of pharmacy and pharmacology 2006;58(6):775-85.
2006: Elvin Stephen J; Eyles James E; Howard Kenneth A; Ravichandran Easwaran; Somavarappu Satyanarayan; Alpar H Oya; Williamson E Diane
Protection against bubonic and pneumonic plague with a single dose microencapsulated sub-unit vaccine.
Vaccine 2006;24(20):4433-9.
2006: Singh Jasvinder; Pandit Sreenivas; Bramwell Vincent W; Alpar H Oya
Diphtheria toxoid loaded poly-(epsilon-caprolactone) nanoparticles as mucosal vaccine delivery systems.
Methods (San Diego, Calif.) 2006;38(2):96-105.
2006: Moschos Sterghios A; Bramwell Vincent W; Somavarapu Satyanarayna; Alpar H Oya
Modulating the adjuvanticity of alum by co-administration of muramyl di-peptide (MDP) or Quil-A.
Vaccine 2006;24(8):1081-6.
2005: Alpar H Oya; Papanicolaou Irene; Bramwell Vincent W
Strategies for DNA vaccine delivery.
Expert opinion on drug delivery 2005;2(5):829-42.
2005: Martin C; Thongborisute J; Takeuchi H; Yamamoto H; Kawashima Y; Alpar H O
Cholesterol-bile salt vesicles as potential delivery vehicles for drug and vaccine delivery.
International journal of pharmaceutics 2005;298(2):339-43.
2005: Hansen Raino K; Zhai Suling; Skepper Jeremy N; Johnston Mike D; Alpar H Oya; Slater Nigel K H
Mechanisms of inactivation of HSV-2 during storage in frozen and lyophilized forms.
Biotechnology progress 2005;21(3):911-7.
2005: Murdan S; Somavarapu S; Ross Alistair C; Alpar H O; Parker M C
Immobilisation of vaccines onto micro-crystals for enhanced thermal stability.
International journal of pharmaceutics 2005;296(1-2):117-21.
2005: Moschos Sterghios A; Bramwell Vincent W; Somavarapu Satyanarayna; Alpar H Oya
Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation.
Vaccine 2005;23(16):1923-30.
2005: Alpar H Oya; Somavarapu S; Atuah K N; Bramwell V W
Biodegradable mucoadhesive particulates for nasal and pulmonary antigen and DNA delivery.
Advanced drug delivery reviews 2005;57(3):411-30.
2004: Moschos S A; Bramwell V W; Somavarapu S; Alpar H O
Adjuvant synergy: the effects of nasal coadministration of adjuvants.
Immunology and cell biology 2004;82(6):628-37.
2004: Eyles J E; Elvin S J; Westwood A; Lebutt C S; Alpar H O; Somavarapu S; Williamson E D
Immunisation against plague by transcutaneous and intradermal application of subunit antigens.
Vaccine 2004;22(31-32):4365-73.
2004: Howard Kenneth A; Li Xiong Wei; Somavarapu Satyanarayana; Singh Jasvinder; Green Nicky; Atuah Kwame N; Ozsoy Yildiz; Seymour Leonard W; Alpar H Oya
Formulation of a microparticle carrier for oral polyplex-based DNA vaccines.
Biochimica et biophysica acta 2004;1674(2):149-57.
2004: Kohli A K; Alpar H O
Potential use of nanoparticles for transcutaneous vaccine delivery: effect of particle size and charge.
International journal of pharmaceutics 2004;275(1-2):13-7.
2004: Papanicolaou I; Briggs S; Alpar H O
Increased resistance of DNA lipoplexes to protein binding in vitro by surface-modification with a multivalent hydrophilic polymer.
Journal of drug targeting 2004;12(8):541-7.
2003: Li Xiong Wei; Lee Daniel Ken Lem; Chan Albert Sun Chi; Alpar H Oya
Sustained expression in mammalian cells with DNA complexed with chitosan nanoparticles.
Biochimica et biophysica acta 2003;1630(1):7-18.
2003: Atuah K N; Walter E; Merkle H P; Alpar H O
Encapsulation of plasmid DNA in PLGA-stearylamine microspheres: a comparison of solvent evaporation and spray-drying methods.
Journal of microencapsulation 2003;20(3):387-99.
2003: Eyles J E; Bramwell V W; Singh J; Williamson E D; Alpar H O
Stimulation of spleen cells in vitro by nanospheric particles containing antigen.
Journal of controlled release : official journal of the Controlled Release Society 2003;86(1):25-32.
2003: Somavarapu S; Bramwell V W; Alpar H O
Oral plasmid DNA delivery systems for genetic immunisation.
Journal of drug targeting 2003;11(8-10):547-53.
2003: Bramwell V W; Somavarapu S; Outschoorn I; Alpar H O
Adjuvant action of melittin following intranasal immunisation with tetanus and diphtheria toxoids.
Journal of drug targeting 2003;11(8-10):525-30.
2003: Eyles J E; Carpenter Z C; Alpar H O; Williamson E D
Immunological aspects of polymer microsphere vaccine delivery systems.
Journal of drug targeting 2003;11(8-10):509-14.
2003: Alpar H Oya
Strategies for vaccine delivery.
Journal of drug targeting 2003;11(8-10):459-61.
2002: Griffin K F; Eyles J E; Spiers I D; Alpar H O; Williamson E D
Protection against plague following immunisation with microencapsulated V antigen is reduced by co-encapsulation with IFN-gamma or IL-4, but not IL-6.
Vaccine 2002;20(31-32):3650-7.
2002: Bramwell Vincent W; Eyles Jim E; Somavarapu Satyanarayana; Alpar H Oya
Liposome/DNA complexes coated with biodegradable PLA improve immune responses to plasmid encoding hepatitis B surface antigen.
Immunology 2002;106(3):412-8.
2002: Flick-Smith Helen C; Eyles Jim E; Hebdon Richard; Waters Emma L; Beedham Richard J; Stagg Tony J; Miller Julie; Alpar H Oya; Baillie Les W J; Williamson E Diane
Mucosal or parenteral administration of microsphere-associated Bacillus anthracis protective antigen protects against anthrax infection in mice.
Infection and immunity 2002;70(4):2022-8.
2002: Howard Kenneth Alan; Alpar H Oya
The development of polyplex-based DNA vaccines.
Journal of drug targeting 2002;10(2):143-51.
2002: Alpar H Oya; Bramwell Vincent W
Current status of DNA vaccines and their route of administration.
Critical reviews in therapeutic drug carrier systems 2002;19(4-5):307-83.
2001: Eyles J E; Bramwell V W; Williamson E D; Alpar H O
Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration.
Vaccine 2001;19(32):4732-42.
2001: Alpar H O; Eyles J E; Williamson E D; Somavarapu S
Intranasal vaccination against plague, tetanus and diphtheria.
Advanced drug delivery reviews 2001;51(1-3):173-201.
2001: Eyles J E; Spiers I D; Williamson E D; Alpar H O
Tissue distribution of radioactivity following intranasal administration of radioactive microspheres.
The Journal of pharmacy and pharmacology 2001;53(5):601-7.
2000: Spiers I D; Eyles J E; Baillie L W; Williamson E D; Alpar H O
Biodegradable microparticles with different release profiles: effect on the immune response after a single administration via intranasal and intramuscular routes.
The Journal of pharmacy and pharmacology 2000;52(10):1195-201.
2000: Eyles J E; Williamson E D; Spiers I D; Alpar H O
Protection studies following bronchopulmonary and intramuscular immunisation with yersinia pestis F1 and V subunit vaccines coencapsulated in biodegradable microspheres: a comparison of efficacy.
Vaccine 2000;18(28):3266-71.
2000: Read M L; Dash P R; Clark A; Howard K A; Oupicky D; Toncheva V; Alpar H O; Schacht E H; Ulbrich K; Seymour L W
Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;10(3):169-77.
2000: Eyles J E; Williamson E D; Alpar H O
Intranasal Administration of InfluenzaVaccines: Current Status.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2000;13(1):35-59.
2000: Eyles J E; Williamson E D; Spiers I D; Stagg A J; Jones S M; Alpar H O
Generation of protective immune responses to plague by mucosal administration of microsphere coencapsulated recombinant subunits.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(1-2):191-200.
1999: Eyles J E; Williamson E D; Alpar H O
Immunological responses to nasal delivery of free and encapsulated tetanus toxoid: studies on the effect of vehicle volume.
International journal of pharmaceutics 1999;189(1):75-9.
1999: Ward K R; Adams G D; Alpar H O; Irwin W J
Protection of the enzyme L-asparaginase during lyophilisation--a molecular modelling approach to predict required level of lyoprotectant.
International journal of pharmaceutics 1999;187(2):153-62.
1999: Spiers I D; Alpar H O; Eyles J E; Bozkir A; Miller J; Williamson E D
Studies on the co-encapsulation, release and integrity of two subunit antigens: rV and rF1 from Yersinia pestis.
The Journal of pharmacy and pharmacology 1999;51(9):991-7.
1999: McAllister S M; Alpar H O; Brown M R
Antimicrobial properties of liposomal polymyxin B.
The Journal of antimicrobial chemotherapy 1999;43(2):203-10.
1998: Eyles J E; Spiers I D; Williamson E D; Alpar H O
Analysis of local and systemic immunological responses after intra-tracheal, intra-nasal and intra-muscular administration of microsphere co-encapsulated Yersinia pestis sub-unit vaccines.
Vaccine 1998;16(20):2000-9.
1998: Eyles J E; Sharp G J; Williamson E D; Spiers I D; Alpar H O
Intra nasal administration of poly-lactic acid microsphere co-encapsulated Yersinia pestis subunits confers protection from pneumonic plague in the mouse.
Vaccine 1998;16(7):698-707.
1998: Griffin K F; Conway B R; Alpar H O; Williamson E D
Immune responses to V antigen of Yersinia pestis co-encapsulated with IFN-gamma: effect of dose and formulation.
Vaccine 1998;16(5):517-21.
1997: Eyles J E; Alpar H O; Conway B R; Keswick M
Oral delivery and fate of poly(lactic acid) microsphere-encapsulated interferon in rats.
The Journal of pharmacy and pharmacology 1997;49(7):669-74.
1997: Sharp G J; Eyles J E; Williamson E D; Brown M R; Alpar H O
Cellular and humoral responses to microencapsulated Yersinia pestis subunit vaccines following oral delivery.
Biochemical Society transactions 1997;25(2):338S.
1997: Alpar H O; Ozsoy Y; Bowen J; Eyles J E; Conway B R; Williamson E D
Potential of particulate carriers for the mucosal delivery of DNA vaccines.
Biochemical Society transactions 1997;25(2):337S.
1996: Williamson E D; Sharp G J; Eley S M; Vesey P M; Pepper T C; Titball R W; Alpar H O
Local and systemic immune response to a microencapsulated sub-unit vaccine for plague.
Vaccine 1996;14(17-18):1613-9.
1996: Almeida A J; Alpar H O
Nasal delivery of vaccines.
Journal of drug targeting 1996;3(6):455-67.
1995: Bowen J C; Reddy R M; Alpar H O; Brown M R; Rouse B T
Expression and stability of herpes simplex virus antigens in Salmonella typhimurium.
Advances in experimental medicine and biology 1995;371B():1543-6.
1994: Poyner E A; Alpar H O; Brown M R
Preparation, properties and the effects of free and liposomal tobramycin on siderophore production by Pseudomonas aeruginosa.
The Journal of antimicrobial chemotherapy 1994;34(1):43-52.
1994: Alpar H O; Almeida A J; Brown M R
Microsphere absorption by the nasal mucosa of the rat.
Journal of drug targeting 1994;2(2):147-9.
1993: Almeida A J; Alpar H O; Brown M R
Immune response to nasal delivery of antigenically intact tetanus toxoid associated with poly(L-lactic acid) microspheres in rats, rabbits and guinea-pigs.
The Journal of pharmacy and pharmacology 1993;45(3):198-203.
1993: Lawrence S M; Alpar H O; McAllister S M; Brown M R
Liposomal (MLV) polymyxin B: physicochemical characterization and effect of surface charge and drug association.
Journal of drug targeting 1993;1(4):303-10.
1992: Almeida A J; Alpar H O; Williamson D; Brown M R
Poly(lactic acid) microspheres as immunological adjuvants for orally delivered cholera toxin b subunit.
Biochemical Society transactions 1992;20(4):316S.
1992: Bowen J C; Alpar H O; Phillpotts R; Brown M R
Mucosal delivery of herpes simplex virus vaccine.
Research in virology 1992;143(4):269-78.
1992: Lewis D A; Field W N; Hayes K; Alpar H O
The use of albumin microspheres in the treatment of carrageenan-induced inflammation in the rat.
The Journal of pharmacy and pharmacology 1992;44(3):271-4.
1989: Alpar H O; Field W N; Hyde R; Lewis D A
The transport of microspheres from the gastro-intestinal tract to inflammatory air pouches in the rat.
The Journal of pharmacy and pharmacology 1989;41(3):194-6.

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