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Ola Dale

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TOP 3
Torill Fladvad; Stein Kaasa; Pål Klepstad; Mette Langaas; Augusto Caraceni; Ola Dale; Frank Skorpen
Variability in UDP-glucuronosyltransferase genes and morphine metabolism: observations from a cross-sectional multicenter study in advanced cancer patients with pain.
Ola Dale; Yibai Li; Andrew A Somogyi; Thomas Sullivan; Yehuda Shavit
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Kristin Moksnes; Jan Henrik Rosland; Olav Spigset; Ørnulf Paulsen; Stein Kaasa; Ola Dale
Serum concentrations of opioids when comparing two switching strategies to methadone for cancer pain.

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All Publications

2013: Torill Fladvad; Stein Kaasa; Pål Klepstad; Mette Langaas; Augusto Caraceni; Ola Dale; Frank Skorpen
Variability in UDP-glucuronosyltransferase genes and morphine metabolism: observations from a cross-sectional multicenter study in advanced cancer patients with pain.
Pharmacogenetics and genomics 2013;23(3):117-26.
2012: Ola Dale; Yibai Li; Andrew A Somogyi; Thomas Sullivan; Yehuda Shavit
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Anesthesia and analgesia 2012;115(4):934-43.
2012: Kristin Moksnes; Jan Henrik Rosland; Olav Spigset; Ørnulf Paulsen; Stein Kaasa; Ola Dale
Serum concentrations of opioids when comparing two switching strategies to methadone for cancer pain.
European journal of clinical pharmacology 2012;68(8):1147-56.
2012: Tormod Landmark; Pål Romundstad; Petter C Borchgrevink; Ola Dale; Stein Kaasa
Estimating the prevalence of chronic pain: validation of recall against longitudinal reporting (the HUNT pain study).
Pain 2012;153(7):1368-73.
2012: Thor W Bjelland; Ola Dale; Bjørn O Haugen; Kjell Kaisen; Stian Lydersen; Kristian Strand; Pål Klepstad
Propofol and remifentanil versus midazolam and fentanyl for sedation during therapeutic hypothermia after cardiac arrest: a randomised trial.
Intensive care medicine 2012;38(6):959-67.
2012: Trine Naalsund Andreassen; Kristin Bjordal; Andrew Davies; Stein Kaasa; Pål Klepstad; Staffan Lundström; Ola Dale
Is oxycodone efficacy reflected in serum concentrations? A multicenter, cross-sectional study in 456 adult cancer patients.
Journal of pain and symptom management 2012;43(4):694-705.
2011: K Moksnes; O Paulsen; J H Rosland; Ola Dale; Pål Klepstad; Stein Kaasa
How to switch from morphine or oxycodone to methadone in cancer patients? a randomised clinical phase II trial.
European journal of cancer (Oxford, England : 1990) 2011;47(16):2463-70.
2011: Tormod Landmark; Pål Romundstad; Petter C Borchgrevink; Stein Kaasa; Ola Dale
Associations between recreational exercise and chronic pain in the general population: evidence from the HUNT 3 study.
Pain 2011;152(10):2241-7.
2011: K Svendsen; Petter C Borchgrevink; O Fredheim; K Hamunen; A Mellbye; Ola Dale
Choosing the unit of measurement counts: the use of oral morphine equivalents in studies of opioid consumption is a useful addition to defined daily doses.
Palliative medicine 2011;25(7):725-32.
2011: Ola Dale; Kristin Moksnes; Stein Kaasa
European Palliative Care Research Collaborative pain guidelines: opioid switching to improve analgesia or reduce side effects. A systematic review.
Palliative medicine 2011;25(5):494-503.
2011: Gro F Bertheussen; Ola Dale; Stein Kaasa; Tormod Landmark; Pål R Romundstad; Jorunn L Helbostad
Associations between physical activity and physical and mental health--a HUNT 3 study.
Medicine and science in sports and exercise 2011;43(7):1220-8.
2011: Pål Klepstad; T Fladvad; Frank Skorpen; Kristin Bjordal; Augusto Caraceni; Ola Dale; A Davies; M Kloke; S Lundström; M Maltoni; Lukas Radbruch; R Sabatowski; V Sigurdardottir; Florian Strasser; Peter M Fayers; Stein Kaasa
Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients.
Pain 2011;152(5):1139-45.
2011: Trine Naalsund Andreassen; Pål Klepstad; Andrew Davies; Kristin Bjordal; Staffan Lundström; Stein Kaasa; Ola Dale
Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients.
European journal of clinical pharmacology 2011;67(5):493-506.
2010: Thor Wilhelm Bjelland; Øyvind Hjertner; Pål Klepstad; Kjell Kaisen; Ola Dale; Bjørn Olav Haugen
Antiplatelet effect of clopidogrel is reduced in patients treated with therapeutic hypothermia after cardiac arrest.
Resuscitation 2010;81(12):1627-31.
2010: Olav Magnus S Fredheim; Ola Dale; Stein Kaasa; Petter C Borchgrevink
[Morphine or oxycodone tablets for pain?].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2010;130(15):1479-81.
2010: Fadia Mayyas; Peter Fayers; Stein Kaasa; Ola Dale
A systematic review of oxymorphone in the management of chronic pain.
Journal of pain and symptom management 2010;39(2):296-308.
2009: Ola Dale; Maria Piribauer; Stein Kaasa; Kristin Moksnes; Heidi Knobel; Pål Klepstad
A double-blind, randomized, crossover comparison between single-dose and double-dose immediate-release oral morphine at bedtime in cancer patients.
Journal of pain and symptom management 2009;37(1):68-76.
2008: Olav Magnus S Fredheim; K Moksnes; Petter C Borchgrevink; Stein Kaasa; Ola Dale
Clinical pharmacology of methadone for pain.
Acta anaesthesiologica Scandinavica 2008;52(7):879-89.
2008: Kristin Moksnes; Olav M Fredheim; Pål Klepstad; Stein Kaasa; Anders Angelsen; Turid Nilsen; Ola Dale
Early pharmacokinetics of nasal fentanyl: is there a significant arterio-venous difference?
European journal of clinical pharmacology 2008;64(5):497-502.
2007: Roar Stenseth; Turid Nilsen; Rune Haaverstad; N Vitale; Ola Dale
Frequent sampling allows detection of short and rapid surges of exhaled ethane during cardiac surgery.
Perfusion 2007;22(6):391-6.
2007: Pål Klepstad; Anne Berit Guttormsen; Ola Dale
Common sense won: engagement from experts repealed Norwegian restrictions for ICU research.
Intensive care medicine 2007;33(10):1827-8.
2007: Ola Dale; J Thoner; Turid Nilsen; T Tveita; Petter C Borchgrevink; Pål Klepstad
Serum and cerebrospinal fluid morphine pharmacokinetics after single doses of intravenous and intramuscular morphine after hip replacement surgery.
European journal of clinical pharmacology 2007;63(9):837-42.
2007: Olav Magnus S Fredheim; Petter C Borchgrevink; Pål Klepstad; Stein Kaasa; Ola Dale
Long term methadone for chronic pain: a pilot study of pharmacokinetic aspects.
European journal of pain (London, England) 2007;11(6):599-604.
2007: Ola Dale; Terje Lund; Hallgeir Bergum; Turid Nilsen; Petter Aadahl; Roar Stenseth
Serial samples of breath ethane can also be analyzed by gas-chromatography.
Respiratory medicine 2007;101(3):679; author reply 680.
2007: Trine Funder Pedersen; Magnus Løberg Thorbjørnsen; Pål Klepstad; Kjetil Sunde; Ola Dale
[Therapeutic hypothermia--pharmacology and pathophysiology].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2007;127(2):163-6.
2006: Ola Dale; Turid Nilsen; Thorsteinn Loftsson; Hanne Hjorth Tønnesen; Pål Klepstad; Stein Kaasa; Trond Holand; Per Gisle Djupesland
Intranasal midazolam: a comparison of two delivery devices in human volunteers.
The Journal of pharmacy and pharmacology 2006;58(10):1311-8.
2006: Olav Magnus S Fredheim; Petter C Borchgrevink; Lars Hegrenaes; Stein Kaasa; Ola Dale; Pål Klepstad
Opioid switching from morphine to methadone causes a minor but not clinically significant increase in QTc time: A prospective 9-month follow-up study.
Journal of pain and symptom management 2006;32(2):180-5.
2006: Ola Dale; Turid Nilsen; Gry Olaussen; Kåre E Tvedt; Frank Skorpen; Olav Smidsrød; Kjell M Vårum
Transepithelial transport of morphine and mannitol in Caco-2 cells: the influence of chitosans of different molecular weights and degrees of acetylation.
The Journal of pharmacy and pharmacology 2006;58(7):909-15.
2006: Hilde Pleym; Vibeke Videm; Alexander Wahba; Arne Asberg; Trond Amundsen; Lise Bjella; Ola Dale; Roar Stenseth
Heparin resistance and increased platelet activation in coronary surgery patients treated with enoxaparin preoperatively.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2006;29(6):933-40.
2006: Hilde Pleym; Alexander Wahba; Vibeke Videm; Arne Asberg; Stian Lydersen; Lise Bjella; Ola Dale; Roar Stenseth
Increased fibrinolysis and platelet activation in elderly patients undergoing coronary bypass surgery.
Anesthesia and analgesia 2006;102(3):660-7.
2006: Olav Magnus S Fredheim; Stein Kaasa; Ola Dale; Pål Klepstad; Nils Inge Landrø; Petter C Borchgrevink
Opioid switching from oral slow release morphine to oral methadone may improve pain control in chronic non-malignant pain: a nine-month follow-up study.
Palliative medicine 2006;20(1):35-41.
2006: Pål Klepstad; Ola Dale
Further restrictions for ICU research.
Intensive care medicine 2006;32(1):175.
2005: Pål Klepstad; Ola Dale; Petter C Borchgrevink; Stein Kaasa; Frank Skorpen
[Genetic variation-- important for the clinical effect of opioids?].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2005;125(19):2655-8.
2005: Hilde Pleym; Ole Tjomsland; Arne Asberg; Stian Lydersen; Alexander Wahba; Lise Bjella; Ola Dale; Roar Stenseth
Effects of autotransfusion of mediastinal shed blood on biochemical markers of myocardial damage in coronary surgery.
Acta anaesthesiologica Scandinavica 2005;49(9):1248-54.
2005: Ola Dale; Pål Klepstad
[Biobank legislation stops research using critically ill patients].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2005;125(18):2524.
2005: Pål Klepstad; Ola Dale; Frank Skorpen; Petter C Borchgrevink; Stein Kaasa
Genetic variability and clinical efficacy of morphine.
Acta anaesthesiologica Scandinavica 2005;49(7):902-8.
2005: Trude Teoline Rakvåg; Pål Klepstad; Cecilie Baar; Tor-Morten Kvam; Ola Dale; Stein Kaasa; Hans E Krokan; Frank Skorpen
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.
Pain 2005;116(1-2):73-8.
2005: Ola Dale; Pål Klepstad; Stein Kaasa
The European Union--not united in opioid use.
Palliative medicine 2005;19(3):177-8.
2005: Stein Kaasa; Ola Dale
Building up research in palliative care: an historical perspective and a case for the future.
Clinics in geriatric medicine 2005;21(1):81-92, viii.
2005: Solveig Sandven Kjesbu; Kristin Moksnes; Pål Klepstad; Heidi Knobel; Stein Kaasa; Ola Dale
[Application of pupillometry and pupillary reactions in medical research].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2005;125(1):29-32.
2004: Pål Klepstad; Trude Teoline Rakvåg; Stein Kaasa; Monica Holthe; Ola Dale; Petter C Borchgrevink; Cecilie Baar; T Vikan; Hans E Krokan; Frank Skorpen
The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease.
Acta anaesthesiologica Scandinavica 2004;48(10):1232-9.
2004: Pål Klepstad; Priscilla Hilton; Jorunn Moen; Stein Kaasa; Petter C Borchgrevink; Kolbjørn Zahlsen; Ola Dale
Day-to-day variations during clinical drug monitoring of morphine, morphine-3-glucuronide and morphine-6-glucuronide serum concentrations in cancer patients. A prospective observational study.
BMC clinical pharmacology 2004;4():7.
2004: Hilde Pleym; Roar Stenseth; Rune Wiseth; Asbjørn Karevold; Ola Dale
Supplemental remifentanil during coronary artery bypass grafting is followed by a transient postoperative cardiac depression.
Acta anaesthesiologica Scandinavica 2004;48(9):1155-62.
2004: Hilde Pleym; Roar Stenseth; Alexander Wahba; Lise Bjella; Arve Tromsdal; Asbjørn Karevold; Ola Dale
Prophylactic treatment with desmopressin does not reduce postoperative bleeding after coronary surgery in patients treated with aspirin before surgery.
Anesthesia and analgesia 2004;98(3):578-84, table of contents.
2003: Pål Klepstad; Petter C Borchgrevink; Ola Dale; Kolbjørn Zahlsen; Trond Aamo; Peter M Fayers; Bjørn Fougner; Stein Kaasa
Routine drug monitoring of serum concentrations of morphine, morphine-3-glucuronide and morphine-6-glucuronide do not predict clinical observations in cancer patients.
Palliative medicine 2003;17(8):679-87.
2003: Ola Dale; Hallgeir Bergum; Terje Lund; Turid Nilsen; Petter Aadahl; Roar Stenseth
A validated method for rapid analysis of ethane in breath and its application in kinetic studies in human volunteers.
Free radical research 2003;37(8):815-21.
2003: Pål Klepstad; Ola Dale; Stein Kaasa; Kolbjørn Zahlsen; Trond Aamo; Peter M Fayers; Petter C Borchgrevink
Influences on serum concentrations of morphine, M6G and M3G during routine clinical drug monitoring: a prospective survey in 300 adult cancer patients.
Acta anaesthesiologica Scandinavica 2003;47(6):725-31.
2003: O Kvalsvik; Petter C Borchgrevink; Lars Hagen; Ola Dale
Randomized, double-blind, placebo-controlled study of the effect of rectal paracetamol on morphine consumption after abdominal hysterectomy.
Acta anaesthesiologica Scandinavica 2003;47(4):451-6.
2003: Hilde Pleym; Roar Stenseth; Alexander Wahba; Lise Bjella; Asbjørn Karevold; Ola Dale
Single-dose tranexamic acid reduces postoperative bleeding after coronary surgery in patients treated with aspirin until surgery.
Anesthesia and analgesia 2003;96(4):923-8, table of contents.
2003: Hilde Pleym; O Spigset; E D Kharasch; Ola Dale
Gender differences in drug effects: implications for anesthesiologists.
Acta anaesthesiologica Scandinavica 2003;47(3):241-59.
2002: Monica Holthe; Pål Klepstad; Kolbjørn Zahlsen; Petter C Borchgrevink; Lars Hagen; Ola Dale; Stein Kaasa; Hans E Krokan; Frank Skorpen
Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy.
European journal of clinical pharmacology 2002;58(5):353-6.
2002: Ola Dale; R Hjortkjaer; Evan D Kharasch
Nasal administration of opioids for pain management in adults.
Acta anaesthesiologica Scandinavica 2002;46(7):759-70.
2000: Hong Qu; Helle S Waagepetersen; M van Hengel; S Wolt; Ola Dale; Geirmund Unsgård; Olav Sletvold; Arne Schousboe; Ursula Sonnewald
Effects of thiopental on transport and metabolism of glutamate in cultured cerebellar granule neurons.
Neurochemistry international 2000;37(2-3):207-15.
2000: Ola Dale; B Mortensen; L Thommesen; B Hagen
Cisplatin toxicity in the rat may be influenced by anaesthetic agents.
Acta anaesthesiologica Scandinavica 2000;44(6):770.
1999: Hong Qu; E Faerø; P Jørgensen; Ola Dale; Sven Erik Gisvold; Geirmund Unsgård; Ursula Sonnewald
Decreased glutamate metabolism in cultured astrocytes in the presence of thiopental.
Biochemical pharmacology 1999;58(6):1075-80.
1999: Ola Dale; H Hynne; K Parivar; E Johansson; M Widman
Pharmacokinetics of eltanolone in male and female patients following intravenous bolus injection.
Acta anaesthesiologica Scandinavica 1999;43(4):415-20.
1999: T Rygnestad; Kolbjørn Zahlsen; O Bergslien; Ola Dale
Focus on mobilisation after lower abdominal surgery. A double-blind randomised comparison of epidural bupivacaine with morphine vs. lidocaine with morphine for postoperative analgesia.
Acta anaesthesiologica Scandinavica 1999;43(4):380-7.
1999: Ola Dale; L Thommesen; B Mortensen; B Hagen
Gender aspects of liver slice incubations with N,N,N-triethylene-thiophosphamide (Thio-TEPA) in rats and mice.
Pharmacology & toxicology 1999;84(3):122-4.
1995: Ola Dale; F E Skjeldestad
[Oral contraceptives and elective surgery. Strategies in Norwegian hospitals, thromboembolic complications and perioperative conception].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1995;115(8):938-40.
1995: B Mortensen; Ola Dale
Effects of hypothermia on the elimination of ethanol, diazepam and oxazepam in rat liver slice incubations.
Acta anaesthesiologica Scandinavica 1995;39(2):199-204.
1994: Ola Dale; F E Skjeldestad; I Rossvoll
A prospective study of fertility and outcome of pregnancy after discontinuation of oral contraception in relation to elective orthopedic surgery.
Acta obstetricia et gynecologica Scandinavica 1994;73(7):567-9.
1994: Ola Dale; A Hole
Biphasic time-course of serum concentrations of clomipramine and desmethylclomipramine after a near-fatal overdose.
Veterinary and human toxicology 1994;36(4):309-10.
1993: K Aarstad; Ola Dale; O Aakervik; Steinar Øvrebø; Kolbjørn Zahlsen
A rapid gas chromatographic method for determination of ethylene glycol in serum and urine.
Journal of analytical toxicology 1993;17(4):218-21.
1993: Ola Dale; E J Frink; L Thommesen; A Gandolfi
Hepatic elimination of diazepam: interactions with albumin, desflurane and sevoflurane.
British journal of anaesthesia 1993;70(4):454-5.
1993: Odd G Nilsen; Ola Dale; B Husebø
Pharmacokinetics of trazodone during multiple dosing to psychiatric patients.
Pharmacology & toxicology 1993;72(4-5):286-9.
1992: Odd G Nilsen; Ola Dale
Single dose pharmacokinetics of trazodone in healthy subjects.
Pharmacology & toxicology 1992;71(2):150-3.
1991: Ola Dale; T Dale
[Anesthetic gases, the ozone layer and the greenhouse effect. How harmful are the anesthetic emissions for the global environment?].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1991;111(17):2115-7.
1991: B Hagen; Ola Dale; G Neverdal; S Azri; Odd G Nilsen
Metabolism and alkylating activity of thio-TEPA in rat liver slice incubation.
Cancer chemotherapy and pharmacology 1991;28(6):441-7.
1988: I Nafstad; S Tollersrud; K Eriksen; A Helgeland; L A Solberg; J Bredesen; Ola Dale
The influence of atenolol and prazosin on serum lipids and atherosclerosis in minipigs fed a hyperlipidemic diet.
General pharmacology 1988;19(5):719-24.
1987: Ola Dale; Odd G Nilsen
Volatile anesthetics and drug serum protein binding.
Anesthesiology 1987;66(5):709-10.
1986: Ola Dale; Odd G Nilsen
Binding and distribution of restrictively and non-restrictively eliminated drugs to serum and liver cell cytosol: effects of volatile anaesthetics.
British journal of anaesthesia 1986;58(1):55-62.
1985: O G Nilsen; A Storhaug; Ola Dale
Binding of tiaprofenic acid to human sera and isolated serum proteins.
Arzneimittel-Forschung 1985;35(6):984-7.
1984: Ola Dale; Odd G Nilsen
Glutathione and glutathione S-transferases in rat liver after inhalation of halothane and enflurane.
Toxicology letters 1984;23(1):61-6.
1984: Ola Dale; Odd G Nilsen
Differences in the serum protein binding of prazosin in man and rat.
Biochemical pharmacology 1984;33(11):1719-24.
1984: Ola Dale; Odd G Nilsen
Displacement of some basic drugs from human serum proteins by enflurane, halothane and their major metabolites. An in vitro study.
British journal of anaesthesia 1984;56(5):535-42.
1983: Ola Dale; K Nielsen; G Westgaard; Odd G Nilsen
Drug metabolizing enzymes in the rat after inhalation of halothane and enflurane. Different pattern of response in liver, kidney and lung and possible implications for toxicity.
British journal of anaesthesia 1983;55(12):1217-24.
1983: A M Cameron; Ola Dale; E Haug; Odd G Nilsen
Inhalation of enflurane and halothane at subanesthetic concentrations and effects on circulating serum testosterone, luteinizing hormone and follicle-stimulating hormone in the male rat.
Toxicology letters 1983;19(3):333-8.
1983: Ola Dale; K Nielsen; Odd G Nilsen
Enzyme induction in liver, kidney and lung after inhalation of halothane and enflurane.
Developments in toxicology and environmental science 1983;11():407-10.