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Sabrina Dallavalle

Research Profile

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Chemicals & Drugs

Anatomy

Procedures

Drug Screening Assays, Antitumor

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Publications

TOP 3
Silvia Castelli; Sabrina Dallavalle; Ilda D'Annessa; Prafulla Katkar; Loana Musso; Sara Vieira; Alessandro Desideri
A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction.
Stefania Butini; Walter Cabri; Giuseppe Campiani; Diana Celona; Sabrina Dallavalle; Filomena Fezza; Sandra Gemma; Samuele Maramai; Lucio Merlini; Patrizia Minetti; Raffaella Napolitano; Franco Borsini; Margherita Brindisi; Mauro Maccarrone
Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties.
Gemma Assante; Sabrina Dallavalle; Piera Anna Martino
Protoilludane sesquiterpenoids as scaffold structures for new antimicrobials against Mannheimia haemolytica.

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All Publications

2013: Silvia Castelli; Sabrina Dallavalle; Ilda D'Annessa; Prafulla Katkar; Loana Musso; Sara Vieira; Alessandro Desideri
A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction.
Archives of biochemistry and biophysics 2013;530(1):7-12.
2013: Stefania Butini; Walter Cabri; Giuseppe Campiani; Diana Celona; Sabrina Dallavalle; Filomena Fezza; Sandra Gemma; Samuele Maramai; Lucio Merlini; Patrizia Minetti; Raffaella Napolitano; Franco Borsini; Margherita Brindisi; Mauro Maccarrone
Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties.
Bioorganic & medicinal chemistry letters 2013;23(2):492-5.
2013: Gemma Assante; Sabrina Dallavalle; Piera Anna Martino
Protoilludane sesquiterpenoids as scaffold structures for new antimicrobials against Mannheimia haemolytica.
The Journal of antibiotics 2013;66(1):43-5.
2012: Sabrina Dallavalle; Claudio Pisano; Franco Zunino
Development and therapeutic impact of HDAC6-selective inhibitors.
Biochemical pharmacology 2012;84(6):756-65.
2012: Alberto Bargiotti; Walter Cabri; Massimo Castorina; Maria Luisa Cervoni; Andrea Ciacci; Sabrina Dallavalle; Michelandrea De Cesare; Grazia Gallo; Giuseppe Giannini; Chiara Giommarelli; Lucio Merlini; Ferdinando Maria Milazzo; Loana Musso; Sergio Penco; Claudio Pisano; Loredana Vesci; Valentina Zuco; Marcella Barbarino; Franco Zunino
Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors.
European journal of medicinal chemistry 2012;53():64-75.
2012: Loana Musso; Sabrina Dallavalle; Gandolfina Farina; Elio Burrone
Natural products as sources of new fungicides: synthesis and antifungal activity of zopfiellin analogues.
Chemical biology & drug design 2012;79(5):780-9.
2012: Giuseppe Giannini; Mario Berardino Guglielmi; Lucio Merlini; Raffaella Nannei; Claudio Pisano; Gianandrea Quattrociocchi; Loredana Vesci; Domenico Alloatti; Gianfranco Battistuzzi; Tiziana Brunetti; Federica Bucci; Maria Grazia Cima; Raffaella Cincinelli; Sabrina Dallavalle; Rosanna Foderà; Walter Cabri
New retinoid derivatives as back-ups of Adarotene.
Bioorganic & medicinal chemistry 2012;20(7):2405-15.
2012: Jyotsna N Chakor; Loana Musso; Paola Sardi; Sabrina Dallavalle
Synthesis and structure-activity relationships of antifungal crassinervic acid analogs.
Chemistry & biodiversity 2012;9(1):41-7.
2011: Salvatore Cananzi; Roberto Artali; Giovanni Luca Beretta; Lucio Merlini; Nadia Zaffaroni; Sabrina Dallavalle
Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D.
Bioorganic & medicinal chemistry 2011;19(16):4971-84.
2010: Loana Musso; Sabrina Dallavalle; Lucio Merlini; Adriana Bava; Gianluca Nasini; Sergio Penco; Giuseppe Giannini; Chiara Giommarelli; Andrea De Cesare; Valentina Zuco; Loredana Vesci; Claudio Pisano; Massimo Castorina; Ferdinando Milazzo; Maria Luisa Cervoni; Fabrizio Dal Piaz; Nunziatina De Tommasi; Franco Zunino
Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors.
Bioorganic & medicinal chemistry 2010;18(16):6031-43.
2010: Sonia Gattinoni; Chiara De Simone; Sabrina Dallavalle; Filomena Fezza; Raffaella Nannei; Natalia Battista; Patrizia Minetti; Gianandrea Quattrociocchi; Antonio Caprioli; Franco Borsini; Walter Cabri; Sergio Penco; Lucio Merlini; Mauro Maccarrone
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
Bioorganic & medicinal chemistry letters 2010;20(15):4406-11.
2010: Sonia Gattinoni; Chiara De Simone; Sabrina Dallavalle; Filomena Fezza; Raffaella Nannei; Daniele Amadio; Patrizia Minetti; Gianandrea Quattrociocchi; Antonio Caprioli; Franco Borsini; Walter Cabri; Sergio Penco; Lucio Merlini; Mauro Maccarrone
Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system.
ChemMedChem 2010;5(3):357-60.
2009: Sabrina Dallavalle; Raffaella Cincinelli; Raffaella Nannei; Lucio Merlini; Gabriella Morini; Sergio Penco; Claudio Pisano; Loredana Vesci; Marcella Barbarino; Valentina Zuco; Michelandrea De Cesare; Franco Zunino
Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.
European journal of medicinal chemistry 2009;44(5):1900-12.
2009: Narayan S Chakor; Loana Musso; Sabrina Dallavalle
First total synthesis of cyrmenin B1.
The Journal of organic chemistry 2009;74(2):844-9.
2009: Leonardo Scaglioni; Stefania Mazzini; Rosanna Mondelli; Sabrina Dallavalle; Sonia Gattinoni; Stella Tinelli; Giovanni L Beretta; Franco Zunino; Enzio Ragg
Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison.
Bioorganic & medicinal chemistry 2009;17(2):484-91.
2008: Claudio Pisano; Michelandrea De Cesare; Giovanni Luca Beretta; Valentina Zuco; Graziella Pratesi; Sergio Penco; Loredana Vesci; Rosanna Foderà; Fabiana Fosca Ferrara; Mario Berardino Guglielmi; Paolo Carminati; Sabrina Dallavalle; Gabriella Morini; Lucio Merlini; Augusto Orlandi; Franco Zunino
Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.
Molecular cancer therapeutics 2008;7(7):2051-9.
2008: Sabrina Dallavalle; Daniela Granza Rocchetta; Loana Musso; Lucio Merlini; Gabriella Morini; Sergio Penco; Stella Tinelli; Giovanni Luca Beretta; Franco Zunino
Synthesis and cytotoxic activity of new 9-substituted camptothecins.
Bioorganic & medicinal chemistry letters 2008;18(9):2781-7.
2008: Sabrina Dallavalle; Sonia Gattinoni; Stefania Mazzini; Leonardo Scaglioni; Lucio Merlini; Stella Tinelli; Giovanni Luca Beretta; Franco Zunino
Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(4):1484-9.
2007: Anna Arnoldi; Sabrina Dallavalle; Lucio Merlini; Loana Musso; Gandolfina Farina; Maddalena Moretti; Lalith Jayasinghe
Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines.
Journal of agricultural and food chemistry 2007;55(20):8187-92.
2007: Raffaella Cincinelli; Sabrina Dallavalle; Raffaella Nannei; Lucio Merlini; Sergio Penco; Giuseppe Giannini; Claudio Pisano; Loredana Vesci; Fabiana Fosca Ferrara; Valentina Zuco; Chiara Zanchi; Franco Zunino
Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids.
Bioorganic & medicinal chemistry 2007;15(14):4863-75.
2007: Eleonora Rizzi; Giuliana Cassinelli; Sabrina Dallavalle; Cinzia Lanzi; Raffaella Cincinelli; Raffaella Nannei; Giuditta Cuccuru; Franco Zunino
Synthesis and RET protein kinase inhibitory activity of 3-arylureidobenzylidene-indolin-2-ones.
Bioorganic & medicinal chemistry letters 2007;17(14):3962-8.
2007: Michelandrea De Cesare; Giovanni Luca Beretta; Stella Tinelli; Valentina Benedetti; Graziella Pratesi; Sergio Penco; Sabrina Dallavalle; Lucio Merlini; Claudio Pisano; Paolo Carminati; Franco Zunino
Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series.
Biochemical pharmacology 2007;73(5):656-64.
2006: Adriana Bava; Sabrina Dallavalle; Giovanni Fronza; Gianluca Nasini; Orso Vajna de Pava
Absolute configuration of sporotricale and structure of 6-hydroxysporotricale.
Journal of natural products 2006;69(12):1793-5.
2006: edoardo parrella; Maurizio Giannì; Maddalena Fratelli; Maria Monica Barzago; Ivan Raska; Luisa Diomede; Mami Kurosaki; Claudio Pisano; Paolo Carminati; Lucio Merlini; Sabrina Dallavalle; Michele Tavecchio; Cécile Rochette-Egly; Mineko Terao; Enrico Garattini
Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamma and retinoid-independent pathways.
Molecular pharmacology 2006;70(3):909-24.
2006: Sabrina Dallavalle; Giuseppe Giannini; Domenico Alloatti; Andrea Casati; Elena Marastoni; Loana Musso; Lucio Merlini; Gabriella Morini; Sergio Penco; Claudio Pisano; Stella Tinelli; Michelandrea De Cesare; Giovanni Luca Beretta; Franco Zunino
Synthesis and cytotoxic activity of polyamine analogues of camptothecin.
Journal of medicinal chemistry 2006;49(17):5177-86.
2006: Raffaella Nannei; Sabrina Dallavalle; Lucio Merlini; Adriana Bava; Gianluca Nasini
Synthesis of (+)-spirolaxine methyl ether.
The Journal of organic chemistry 2006;71(16):6277-80.
2005: Eleonora Rizzi; Sabrina Dallavalle; Lucio Merlini; Giovanni Luca Beretta; Graziella Pratesi; Franco Zunino
A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin.
Bioorganic & medicinal chemistry letters 2005;15(19):4313-6.
2005: Raffaella Cincinelli; Sabrina Dallavalle; Raffaella Nannei; Serena Carella; Daniele De Zani; Lucio Merlini; Sergio Penco; Enrico Garattini; Giuseppe Giannini; Claudio Pisano; Loredana Vesci; Paolo Carminati; Valentina Zuco; Chiara Zanchi; Franco Zunino
Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.
Journal of medicinal chemistry 2005;48(15):4931-46.
2004: Sabrina Dallavalle; Lucio Merlini; Giovanni Luca Beretta; Stella Tinelli; Franco Zunino
Synthesis and cytotoxic activity of substituted luotonin A derivatives.
Bioorganic & medicinal chemistry letters 2004;14(23):5757-61.
2004: Sabrina Dallavalle; Lucio Merlini; Gabriella Morini; Loana Musso; Sergio Penco; Giovanni Luca Beretta; Stella Tinelli; Franco Zunino
Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin.
European journal of medicinal chemistry 2004;39(6):507-13.
2004: Sabrina Dallavalle; Lalith Jayasinghe; B M M Kumarihamy; Lucio Merlini; Loana Musso; Leonardo Scaglioni
A new 3,4-seco-lupane derivative from Lasianthus gardneri.
Journal of natural products 2004;67(5):911-3.
2004: Stefania Mazzini; Maria Cristina Bellucci; Sabrina Dallavalle; Franca Fraternali; Rosanna Mondelli
Mode of binding of camptothecins to double helix oligonucleotides.
Organic & biomolecular chemistry 2004;2(4):505-13.
2003: Giulia Bianchi; Sabrina Dallavalle; Lucio Merlini; Gianluca Nasini; Sergio Quaroni
A new azoxyalkene from a strain of an actinomadura-like fungus.
Planta medica 2003;69(6):574-6.
2003: Barbara Biasotti; Sabrina Dallavalle; Lucio Merlini; Carlo Farina; Stefania Gagliardi; Carlo Parini; Pietro Belfiore
Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase.
Bioorganic & medicinal chemistry 2003;11(10):2247-54.
2003: Raffaella Cincinelli; Sabrina Dallavalle; Lucio Merlini; Sergio Penco; Claudio Pisano; Paolo Carminati; Giuseppe Giannini; Loredana Vesci; carlo gaetano; Barbara Illy; Valentina Zuco; Rosanna Supino; Franco Zunino
A novel atypical retinoid endowed with proapoptotic and antitumor activity.
Journal of medicinal chemistry 2003;46(6):909-12.
2001: Sabrina Dallavalle; A Ferrari; Barbara Biasotti; Lucio Merlini; Sergio Penco; Grazia Gallo; MAURO MARZI; Maria Ornella Tinti; Roberta Martinelli; Claudio Pisano; Paolo Carminati; Nives Carenini; Giovanni Luca Beretta; Paola Perego; Michelandrea De Cesare; Graziella Pratesi; Franco Zunino
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity.
Journal of medicinal chemistry 2001;44(20):3264-74.
2001: Sabrina Dallavalle; A Ferrari; Lucio Merlini; Sergio Penco; Nives Carenini; Michelandrea De Cesare; Paola Perego; Graziella Pratesi; Franco Zunino
Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.
Bioorganic & medicinal chemistry letters 2001;11(3):291-4.
2000: Sabrina Dallavalle; T Delsoldato; A Ferrari; Lucio Merlini; Sergio Penco; Nives Carenini; Paola Perego; Michelandrea De Cesare; Graziella Pratesi; Franco Zunino
Novel 7-substituted camptothecins with potent antitumor activity.
Journal of medicinal chemistry 2000;43(21):3963-9.