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Philip Aaronson

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TOP 3
Philip I Aaronson
Does TRPC3 macrodominate the myoendothelial gap junction microdomain?
Lamia Heikal; Gary P Martin; Manasi Nandi; Philip I Aaronson; Albert Ferro; Lea Ann Dailey
S-nitrosophytochelatins: investigation of the bioactivity of an oligopeptide nitric oxide delivery system.
Michelle J Connolly; Philip I Aaronson
Key role of the RhoA/Rho kinase system in pulmonary hypertension.

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All Publications

2012: Philip I Aaronson
Does TRPC3 macrodominate the myoendothelial gap junction microdomain?
Cardiovascular research 2012;95(4):399-400.
2011: Lamia Heikal; Gary P Martin; Manasi Nandi; Philip I Aaronson; Albert Ferro; Lea Ann Dailey
S-nitrosophytochelatins: investigation of the bioactivity of an oligopeptide nitric oxide delivery system.
Biomacromolecules 2011;12(6):2103-13.
2011: Michelle J Connolly; Philip I Aaronson
Key role of the RhoA/Rho kinase system in pulmonary hypertension.
Pulmonary pharmacology & therapeutics 2011;24(1):1-14.
2011: Vladimir A Snetkov; Sergey V Smirnov; Justin Kua; Philip I Aaronson; Jeremy P T Ward; Greg A Knock
Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways.
Cardiovascular research 2011;89(1):214-24.
2010: Michelle J Connolly; Philip I Aaronson
Cell redox state and hypoxic pulmonary vasoconstriction: recent evidence and possible mechanisms.
Respiratory physiology & neurobiology 2010;174(3):165-74.
2009: Greg A Knock; Vladimir A Snetkov; Yasin Shaifta; Michelle Connolly; Svetlana Drndarski; Anthony Noah; Ghazaleh E Pourmahram; Silke Becker; Philip I Aaronson; Jeremy P T Ward
Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization.
Free radical biology & medicine 2009;46(5):633-42.
2008: Greg A Knock; Vladimir A Snetkov; Yasin Shaifta; Svetlana Drndarski; Jeremy P T Ward; Philip I Aaronson
Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery.
Cardiovascular research 2008;80(3):453-62.
2008: Ghazaleh Esmaeil Pourmahram; Vladimir A Snetkov; Yasin Shaifta; Svetlana Drndarski; Greg A Knock; Philip I Aaronson; Jeremy P T Ward
Constriction of pulmonary artery by peroxide: role of Ca2+ release and PKC.
Free radical biology & medicine 2008;45(10):1468-76.
2008: Vladimir A Snetkov; Gavin D Thomas; Bonnie Teague; Richard M Leach; Yasin Shaifta; Greg A Knock; Philip I Aaronson; Jeremy P T Ward
Low concentrations of sphingosylphosphorylcholine enhance pulmonary artery vasoreactivity: the role of protein kinase C delta and Ca2+ entry.
Hypertension 2008;51(2):239-45.
2008: Greg A Knock; Yasin Shaifta; Vladimir A Snetkov; Benjamin Vowles; Svetlana Drndarski; Jeremy P T Ward; Philip I Aaronson
Interaction between src family kinases and rho-kinase in agonist-induced Ca2+-sensitization of rat pulmonary artery.
Cardiovascular research 2008;77(3):570-9.
2007: Silke Becker; Lyn M Moir; Vladimir A Snetkov; Philip I Aaronson
Hypoxic pulmonary vasoconstriction in intact rat intrapulmonary arteries is not initiated by inhibition of Na+-Ca2+ exchange.
American journal of physiology. Lung cellular and molecular physiology 2007;293(4):L982-90.
2007: Anuradha Srivastava; Praveen K Gupta; Greg A Knock; Philip I Aaronson; Praveen Gupta; Vellanki Ravi Prakash
Effect of ceramide on the contractility of pregnant rat uterus.
European journal of pharmacology 2007;567(1-2):159-65.
2006: Sheeja Joy; Richard C M Siow; David J Rowlands; Marko Becker; Amanda Wyatt; Philip I Aaronson; Clive W Coen; Imre Kallo; Ron Jacob; Giovanni E Mann
The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells.
The Journal of biological chemistry 2006;281(37):27335-45.
2006: Greg A Knock; Katharina Mahn; Giovanni E Mann; Jeremy P T Ward; Philip I Aaronson
Dietary soy modulates endothelium-dependent relaxation in aged male rats: Increased agonist-induced endothelium-derived hyperpolarising factor and basal nitric oxide activity.
Free radical biology & medicine 2006;41(5):731-9.
2006: Philip I Aaronson; Uzma Sarwar; Stephanie Gin; Uli Rockenbauch; Michelle Connolly; Alexandra Tillet; Sarah Watson; Bing Liu; Rachel Tribe
A role for voltage-gated, but not Ca2+-activated, K+ channels in regulating spontaneous contractile activity in myometrium from virgin and pregnant rats.
British journal of pharmacology 2006;147(7):815-24.
2006: Vladimir A Snetkov; Greg A Knock; Lynne Baxter; Gavin D Thomas; Jeremy P T Ward; Philip I Aaronson
Mechanisms of the prostaglandin F2alpha-induced rise in [Ca2+]i in rat intrapulmonary arteries.
The Journal of physiology 2006;571(Pt 1):147-63.
2006: Silke Becker; Greg A Knock; Vladimir A Snetkov; Jeremy P T Ward; Philip I Aaronson
Role of capacitative Ca2+ entry but not Na+/Ca2+ exchange in hypoxic pulmonary vasoconstriction in rat intrapulmonary arteries.
Novartis Foundation symposium 2006;272():259-68; discussion 268-79.
2006: Philip I Aaronson; Tom P Robertson; Greg A Knock; Silke Becker; Tristan H Lewis; Vladimir A Snetkov; Jeremy P T Ward
Hypoxic pulmonary vasoconstriction: mechanisms and controversies.
The Journal of physiology 2006;570(Pt 1):53-8.
2005: Greg A Knock; Anushika S De Silva; Vladimir A Snetkov; Richard C M Siow; Gavin D Thomas; Mitsuya Shiraishi; Michael P Walsh; Jeremy P T Ward; Philip I Aaronson
Modulation of PGF2alpha- and hypoxia-induced contraction of rat intrapulmonary artery by p38 MAPK inhibition: a nitric oxide-dependent mechanism.
American journal of physiology. Lung cellular and molecular physiology 2005;289(6):L1039-48.
2005: Katharina Mahn; Consuelo Borrás; Greg A Knock; Paul Taylor; Imran Y Khan; David Sugden; Lucilla Poston; Jeremy P T Ward; Richard M Sharpe; José Viña; Philip I Aaronson; Giovanni E Mann
Dietary soy isoflavone induced increases in antioxidant and eNOS gene expression lead to improved endothelial function and reduced blood pressure in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(12):1755-7.
2005: Gavin D Thomas; Vladimir A Snetkov; Rupal Patel; Richard M Leach; Philip I Aaronson; Jeremy P T Ward
Sphingosylphosphorylcholine-induced vasoconstriction of pulmonary artery: activation of non-store-operated Ca2+ entry.
Cardiovascular research 2005;68(1):56-64.
2005: Jeremy P T Ward; Tom P Robertson; Philip I Aaronson
Capacitative calcium entry: a central role in hypoxic pulmonary vasoconstriction?
American journal of physiology. Lung cellular and molecular physiology 2005;289(1):L2-4.
2005: Marie Vanková; Vladimir A Snetkov; Greg A Knock; Philip I Aaronson; Jeremy P T Ward
Euhydric hypercapnia increases vasoreactivity of rat pulmonary arteries via HCO3- transport and depolarisation.
Cardiovascular research 2005;65(2):505-12.
2004: Jeremy P T Ward; Greg A Knock; Vladimir A Snetkov; Philip I Aaronson
Protein kinases in vascular smooth muscle tone--role in the pulmonary vasculature and hypoxic pulmonary vasoconstriction.
Pharmacology & therapeutics 2004;104(3):207-31.
2004: Jeremy P T Ward; Vladimir A Snetkov; Philip I Aaronson
Calcium, mitochondria and oxygen sensing in the pulmonary circulation.
Cell calcium 2004;36(3-4):209-20.
2003: Vladimir A Snetkov; Philip I Aaronson; Jeremy P T Ward; Greg A Knock; Tom P Robertson
Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat.
British journal of pharmacology 2003;140(1):97-106.
2003: Tom P Robertson; Philip I Aaronson; Jeremy P T Ward
Ca2+ sensitization during sustained hypoxic pulmonary vasoconstriction is endothelium dependent.
American journal of physiology. Lung cellular and molecular physiology 2003;284(6):L1121-6.
2002: Philip I Aaronson; Tom P Robertson; Jeremy P T Ward
Endothelium-derived mediators and hypoxic pulmonary vasoconstriction.
Respiratory physiology & neurobiology 2002;132(1):107-20.
2002: Greg A Knock; D Psaroudakis; SE Abbot; Philip I Aaronson
Propionate-induced relaxation in rat mesenteric arteries: a role for endothelium-derived hyperpolarising factor.
The Journal of physiology 2002;538(Pt 3):879-90.
2002: Sergey Smirnov; Richard Beck; Paolo Tammaro; Tetsuro Ishii; Philip I Aaronson
Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries.
The Journal of physiology 2002;538(Pt 3):867-78.
2001: Greg A Knock; Rachel Tribe; A A Hassoni; Philip I Aaronson
Modulation of potassium current characteristics in human myometrial smooth muscle by 17beta-estradiol and progesterone.
Biology of reproduction 2001;64(5):1526-34.
2001: Tom P Robertson; Jeremy P T Ward; Philip I Aaronson
Hypoxia induces the release of a pulmonary-selective, Ca(2+)-sensitising, vasoconstrictor from the perfused rat lung.
Cardiovascular research 2001;50(1):145-50.
2000: Tom P Robertson; Michelle Dipp; Jeremy P T Ward; Philip I Aaronson; A M Evans
Inhibition of sustained hypoxic vasoconstriction by Y-27632 in isolated intrapulmonary arteries and perfused lung of the rat.
British journal of pharmacology 2000;131(1):5-9.
2000: Sergey Smirnov; Greg A Knock; Andriy Belevych; Philip I Aaronson
Mechanism of effect of extracellular pH on L-type Ca(2+) channel currents in human mesenteric arterial cells.
American journal of physiology. Heart and circulatory physiology 2000;279(1):H76-85.
2000: Tom P Robertson; D Hague; Philip I Aaronson; Jeremy P T Ward
Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat.
The Journal of physiology 2000;525 Pt 3():669-80.
2000: S K Mishra; SE Abbot; Z Choudhury; M Cheng; N Khatab; N J Maycock; A Zavery; Philip I Aaronson
Endothelium-dependent relaxation of rat aorta and main pulmonary artery by the phytoestrogens genistein and daidzein.
Cardiovascular research 2000;46(3):539-46.
1999: Santosh K Mishra; Philip I Aaronson
Differential block by troglitazone and rosiglitazone of glibenclamide-sensitive K(+) current in rat aorta myocytes.
European journal of pharmacology 1999;386(1):121-5.
1999: Greg A Knock; Sergey Smirnov; Philip I Aaronson
Voltage-gated K+ currents in freshly isolated myocytes of the pregnant human myometrium.
The Journal of physiology 1999;518 ( Pt 3)():769-81.
1999: Greg A Knock; Philip I Aaronson
Calcium antagonistic properties of the cyclooxygenase-2 inhibitor nimesulide in human myometrial myocytes.
British journal of pharmacology 1999;127(6):1470-8.
1999: Jeremy P T Ward; Philip I Aaronson
Mechanisms of hypoxic pulmonary vasoconstriction: can anyone be right?
Respiration physiology 1999;115(3):261-71.
1999: Greg A Knock; Santosh K Mishra; Philip I Aaronson
Differential effects of insulin-sensitizers troglitazone and rosiglitazone on ion currents in rat vascular myocytes.
European journal of pharmacology 1999;368(1):103-9.
1998: R Beck; S Bertolino; SE Abbot; Philip I Aaronson; Sergey Smirnov
Modulation of arachidonic acid release and membrane fluidity by albumin in vascular smooth muscle and endothelial cells.
Circulation research 1998;83(9):923-31.
1998: Robert J Sawdy; Greg A Knock; Phillip R Bennett; Lucilla Poston; Philip I Aaronson
Effect of nimesulide and indomethacin on contractility and the Ca2+ channel current in myometrial smooth muscle from pregnant women.
British journal of pharmacology 1998;125(6):1212-7.
1998: Sergey Smirnov; Philip I Aaronson
pH-dependent block of the L-type Ca2+ channel current by diltiazem in human mesenteric arterial myocytes.
European journal of pharmacology 1998;360(1):81-90.
1998: Sergey Smirnov; Greg A Knock; Philip I Aaronson
Effects of the 5-lipoxygenase activating protein inhibitor MK886 on voltage-gated and Ca2+-activated K+ currents in rat arterial myocytes.
British journal of pharmacology 1998;124(3):572-8.
1996: Sergey Smirnov; Philip I Aaronson
Modulatory effects of arachidonic acid on the delayed rectifier K+ current in rat pulmonary arterial myocytes. Structural aspects and involvement of protein kinase C.
Circulation research 1996;79(1):20-31.
1996: William McKinnon; Philip I Aaronson; Greg A Knock; J Graves; L Poston
Mechanism of lactate-induced relaxation of isolated rat mesenteric resistance arteries.
The Journal of physiology 1996;490 ( Pt 3)():783-92.
1996: Philip I Aaronson; William McKinnon; L Poston
Mechanism of butyrate-induced vasorelaxation of rat mesenteric resistance artery.
British journal of pharmacology 1996;117(2):365-71.
1995: Sergey Smirnov; Philip I Aaronson
Inhibition of vascular smooth muscle cell K+ currents by tyrosine kinase inhibitors genistein and ST 638.
Circulation research 1995;76(2):310-6.
1995: Tom P Robertson; Philip I Aaronson; Jeremy P T Ward
Hypoxic vasoconstriction and intracellular Ca2+ in pulmonary arteries: evidence for PKC-independent Ca2+ sensitization.
The American journal of physiology 1995;268(1 Pt 2):H301-7.
1994: Sergey Smirnov; Philip I Aaronson
Alteration of the transmembrane K+ gradient during development of delayed rectifier in isolated rat pulmonary arterial cells.
The Journal of general physiology 1994;104(2):241-64.
1994: Sergey Smirnov; Tom P Robertson; Jeremy P T Ward; Philip I Aaronson
Chronic hypoxia is associated with reduced delayed rectifier K+ current in rat pulmonary artery muscle cells.
The American journal of physiology 1994;266(1 Pt 2):H365-70.
1994: Philip I Aaronson
Intracellular Ca2+ release in cerebral arteries.
Pharmacology & therapeutics 1994;64(3):493-507.
1992: Sergey Smirnov; Philip I Aaronson
Ca2+ currents in single myocytes from human mesenteric arteries: evidence for a physiological role of L-type channels.
The Journal of physiology 1992;457():455-75.
1992: Sergey Smirnov; Philip I Aaronson
Ca(2+)-activated and voltage-gated K+ currents in smooth muscle cells isolated from human mesenteric arteries.
The Journal of physiology 1992;457():431-54.
1992: Sergey Smirnov; Philip I Aaronson; S N Russell
Cromakalim does not act as a calcium antagonist in isolated human mesenteric artery cells.
European journal of pharmacology 1992;217(1):105-8.
1992: S N Russell; Sergey Smirnov; Philip I Aaronson
Effects of BRL 38227 on potassium currents in smooth muscle cells isolated from rabbit portal vein and human mesenteric artery.
British journal of pharmacology 1992;105(3):549-56.
1991: Philip I Aaronson; S N Russell
Rabbit intestinal smooth muscle calcium current in solutions with physiological calcium concentration.
Experimental physiology 1991;76(4):539-51.
1991: Philip I Aaronson; L Poston; R G Woolfson; Sergey Smirnov
Evidence for Na-Ca exchange in human resistance arteries.
Annals of the New York Academy of Sciences 1991;639():521-30.