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Imad Damaj

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TOP 3
Kia J Jackson; J Michael McIntosh; Pretal P Muldoon; Sarah S Sanjakdar; M Imad Damaj
The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse.
Kenneth S Kendler; John Myers; M Imad Damaj; Xianging Chen
Early smoking onset and risk for subsequent nicotine dependence: a monozygotic co-twin control study.
K J Jackson; J P McLaughlin; F I Carroll; M Imad Damaj
Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice.

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2013: Kia J Jackson; J Michael McIntosh; Pretal P Muldoon; Sarah S Sanjakdar; M Imad Damaj
The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse.
Neuropharmacology 2013;70():228-35.
2013: Kenneth S Kendler; John Myers; M Imad Damaj; Xianging Chen
Early smoking onset and risk for subsequent nicotine dependence: a monozygotic co-twin control study.
The American journal of psychiatry 2013;170(4):408-13.
2013: K J Jackson; J P McLaughlin; F I Carroll; M Imad Damaj
Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice.
Psychopharmacology 2013;226(4):763-8.
2013: Pretal P Muldoon; Loren H Parsons; Aron H Lichtman; M Imad Damaj
The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence.
Life sciences 2013;92(8-9):458-62.
2013: Anton Dawson; Micheal F Miles; M Imad Damaj
The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse.
Alcohol (Fayetteville, N.Y.) 2013;47(2):85-94.
2013: Kelen Freitas; F Ivy Carroll; M Imad Damaj
The antinociceptive effects of nicotinic receptors α7-positive allosteric modulators in murine acute and tonic pain models.
The Journal of pharmacology and experimental therapeutics 2013;344(1):264-75.
2013: Shakir AlSharari; Wimolnut Auttachoat; Guy A Cabral; Gabriela A Ferreira; Aron H Lichtman; Omer Shahab; Kimber L White; Rehab A Abdullah; Hamid Akbarali; M Imad Damaj
Novel insights on the effect of nicotine in a murine colitis model.
The Journal of pharmacology and experimental therapeutics 2013;344(1):207-17.
2012: Sheri D Grabus; Frank Ivy Carroll; M Imad Damaj
Bupropion and its main metabolite reverse nicotine chronic tolerance in the mouse.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012;14(11):1356-61.
2012: Shakir AlSharari; F Ivy Carroll; J Michael McIntosh; M Imad Damaj
The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models.
The Journal of pharmacology and experimental therapeutics 2012;342(3):742-9.
2012: K M Tobey; D M Walentiny; Jenny L Wiley; Marc R Azar; F I Carroll; M Imad Damaj; olivier george; L S Harris; G F Koob; Robert Vann
Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice.
Psychopharmacology 2012;223(2):159-68.
2012: Pauline Ondachi; Ana Castro; M Imad Damaj; Charles W Luetje; Wayne Mascarella; Hernán A Navarro; F Ivy Carroll
Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine.
Journal of medicinal chemistry 2012;55(14):6512-22.
2012: Andrew A George; Linda M Lucero; Ronald J Lukas; Xiangning Chen; M Imad Damaj; Paul Whiteaker
Function of human α3β4α5 nicotinic acetylcholine receptors is reduced by the α5(D398N) variant.
The Journal of biological chemistry 2012;287(30):25151-62.
2012: Kia J Jackson; Sarah S Sanjakdar; Xiangning Chen; M Imad Damaj
Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice.
PloS one 2012;7(11):e51154.
2011: Dena Kota; Michael J Marks; Sarah Sanjakdar; karem alzoubi; Omar Khabour; M Imad Damaj
Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice.
Biochemical pharmacology 2011;82(8):1008-14.
2011: Kia J Jackson; Michael F Miles; Xiangning Chen; JoLynne Harenza; M Imad Damaj
The neuropeptide galanin and variants in the GalR1 gene are associated with nicotine dependence.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(11):2339-48.
2011: F Ivy Carroll; Ana Z Muresan; Bruce E Blough; Hernán A Navarro; Wayne Mascarella; J Brek Eaton; Xiaodong Huang; M Imad Damaj; Ronald J. Lukas
Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine.
Journal of medicinal chemistry 2011;54(5):1441-8.
2011: olivier george; Allison Lloyd; F Ivy Carroll; M Imad Damaj; George F Koob
Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration.
Psychopharmacology 2011;213(4):715-22.
2010: Galya R Abdrakhmanova; Bruce E Blough; Carey Nesloney; Hernán A Navarro; M Imad Damaj; F Ivy Carroll
In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs.
Neuropharmacology 2010;59(6):511-7.
2010: Yanan Zhang; Anne F Gilliam; Rangan Maitra; M Imad Damaj; Julianne M Tajuba; Herbert H Seltzman; Brian Thomas
Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor.
Journal of medicinal chemistry 2010;53(19):7048-60.
2010: Galya R Abdrakhmanova; Shakir D AlSharari; Minho Kang; M Imad Damaj; Hamid Akbarali
{alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis.
American journal of physiology. Gastrointestinal and liver physiology 2010;299(3):G761-8.
2010: M Imad Damaj; Sheri D Grabus; Hernán A Navarro; Robert Vann; Jonathan A Warner; Lindsey S King; Jenny L Wiley; Bruce E Blough; Ronald J. Lukas; F Ivy Carroll
Effects of hydroxymetabolites of bupropion on nicotine dependence behavior in mice.
The Journal of pharmacology and experimental therapeutics 2010;334(3):1087-95.
2010: K J Jackson; Michael J Marks; Robert Vann; Xiangning Chen; T F Gamage; J A Warner; M Imad Damaj
Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice.
The Journal of pharmacology and experimental therapeutics 2010;334(1):137-46.
2010: Ronald J. Lukas; Ana Z Muresan; M Imad Damaj; Bruce E Blough; Xiaodong Huang; Hernán A Navarro; S Wayne Mascarella; J Brek Eaton; Syndia K Marxer-Miller; F Ivy Carroll
Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation.
Journal of medicinal chemistry 2010;53(12):4731-48.
2010: K J Jackson; Frank Ivy Carroll; S Stevens Negus; M Imad Damaj
Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse.
Psychopharmacology 2010;210(2):285-94.
2010: F Ivy Carroll; Wei Ma; Liu Deng; Hernán A Navarro; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists.
Journal of natural products 2010;73(3):306-12.
2010: F Ivy Carroll; Bruce E Blough; Wayne Mascarella; Hernán A Navarro; J Brek Eaton; Ronald J. Lukas; M Imad Damaj
Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation.
Journal of medicinal chemistry 2010;53(5):2204-14.
2009: K J Jackson; J M McIntosh; Darlene H Brunzell; S S Sanjakdar; M Imad Damaj
The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal.
The Journal of pharmacology and experimental therapeutics 2009;331(2):547-54.
2009: Kia J Jackson; Carrie L Walters; Michael F Miles; Billy R Martin; M Imad Damaj
Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice.
Neuropharmacology 2009;57(4):347-55.
2009: K J Jackson; C L Walters; M Imad Damaj
Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo.
The Journal of pharmacology and experimental therapeutics 2009;330(2):541-9.
2009: K J Jackson; M Imad Damaj
L-type calcium channels and calcium/calmodulin-dependent kinase II differentially mediate behaviors associated with nicotine withdrawal in mice.
The Journal of pharmacology and experimental therapeutics 2009;330(1):152-61.
2009: K J Jackson; D H Kota; Billy R Martin; M Imad Damaj
The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion.
Neuropharmacology 2009;56(6-7):970-4.
2008: Galya R Abdrakhmanova; F Ivy Carroll; M Imad Damaj; Billy R Martin
3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs.
Neuropharmacology 2008;55(8):1287-92.
2008: Lisa L Merritt; Billy R Martin; C Walters; Aron H Lichtman; M Imad Damaj
The endogenous cannabinoid system modulates nicotine reward and dependence.
The Journal of pharmacology and experimental therapeutics 2008;326(2):483-92.
2008: D Kota; Billy R Martin; M Imad Damaj
Age-dependent differences in nicotine reward and withdrawal in female mice.
Psychopharmacology 2008;198(2):201-10.
2008: K J Jackson; Billy R Martin; Jean-Pierre Changeux; M Imad Damaj
Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs.
The Journal of pharmacology and experimental therapeutics 2008;325(1):302-12.
2008: F Ivy Carroll; Yasuno Yokota; Wei Ma; Jeffrey R Lee; Lawrence E Brieaddy; Jason P Burgess; Hernán A Navarro; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs.
Bioorganic & medicinal chemistry 2008;16(2):746-54.
2007: Frank carroll; T Philip Robinson; Lawrence E Brieaddy; Robert N Atkinson; Wayne Mascarella; M Imad Damaj; Billy R Martin; Hernán A Navarro
Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine.
Journal of medicinal chemistry 2007;50(25):6383-91.
2007: M Imad Damaj
Behavioral modulation of neuronal calcium/calmodulin-dependent protein kinase II activity: differential effects on nicotine-induced spinal and supraspinal antinociception in mice.
Biochemical pharmacology 2007;74(8):1247-52.
2007: D Kota; Billy R Martin; Susan E Robinson; M Imad Damaj
Nicotine dependence and reward differ between adolescent and adult male mice.
The Journal of pharmacology and experimental therapeutics 2007;322(1):399-407.
2007: Henrik H Hansen; Daniel B Timmermann; Dan Peters; Carrie Walters; M Imad Damaj; Jens D Mikkelsen
Alpha-7 nicotinic acetylcholine receptor agonists selectively activate limbic regions of the rat forebrain: an effect similar to antipsychotics.
Journal of neuroscience research 2007;85(8):1810-8.
2007: M Imad Damaj; Carlos Fonck; Michael J Marks; Purnima Deshpande; Cesar Labarca; Henry A Lester; Allan C Collins; Billy R Martin
Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice.
The Journal of pharmacology and experimental therapeutics 2007;321(3):1161-9.
2007: Shannon G Matta; David J K Balfour; Neal L Benowitz; R Thomas Boyd; Jerry J Buccafusco; Anthony R Caggiula; Caroline R Craig; Allan C Collins; M Imad Damaj; Eric C Donny; Phillip S Gardiner; Sharon R Grady; Ulrike Heberlein; Sherry S Leonard; Edward Levin; Ronald J. Lukas; Athina Markou; Michael J Marks; Sarah E McCallum; Neeraja Parameswaran; Kenneth A Perkins; Marina R Picciotto; Maryka Quik; Jed E Rose; Adrian Rothenfluh; William R Schafer; Ian P Stolerman; Rachel F Tyndale; Jeanne M Wehner; Jeffrey M Zirger
Guidelines on nicotine dose selection for in vivo research.
Psychopharmacology 2007;190(3):269-319.
2007: F Ivy Carroll; Wei Ma; Hernán A Navarro; Philip Abraham; Scott A Wolckenhauer; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.
Bioorganic & medicinal chemistry 2007;15(2):678-85.
2007: M Imad Damaj
Nicotinic regulation of calcium/calmodulin-dependent protein kinase II activation in the spinal cord.
The Journal of pharmacology and experimental therapeutics 2007;320(1):244-9.
2007: M Imad Damaj; Eric C K Siu; E M Sellers; Rachel F Tyndale; Billy R Martin
Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice.
The Journal of pharmacology and experimental therapeutics 2007;320(1):250-7.
2006: Jerry Wright; Robert Vann; Thomas F Gamage; M Imad Damaj; Jenny L Wiley
Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats.
Pharmacology, biochemistry, and behavior 2006;85(3):507-13.
2006: M Imad Damaj; Jianfeng Zheng; Billy R Martin; Michael J Kuhar
Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain.
Peptides 2006;27(8):2019-23.
2006: Frank carroll; Xingding Hu; Hernán A Navarro; Jeffrey Deschamps; Galya R Abdrakhmanova; M Imad Damaj; Billy R Martin
Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes.
Journal of medicinal chemistry 2006;49(11):3244-50.
2006: Galya R Abdrakhmanova; M Imad Damaj; Frank carroll; Billy R Martin
2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs.
Molecular pharmacology 2006;69(6):1945-52.
2006: Sheri D Grabus; Billy R Martin; Sharon E Brown; M Imad Damaj
Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists.
Psychopharmacology 2006;184(3-4):456-63.
2006: Carrie L Walters; Sharon Brown; Jean-Pierre Changeux; Billy Martin; M Imad Damaj
The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice.
Psychopharmacology 2006;184(3-4):339-44.
2005: Frank carroll; Lawrence E Brieaddy; Hernán A Navarro; M Imad Damaj; Billy R Martin
Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues.
Journal of medicinal chemistry 2005;48(23):7491-5.
2005: M Imad Damaj
Calcium-acting drugs modulate expression and development of chronic tolerance to nicotine-induced antinociception in mice.
The Journal of pharmacology and experimental therapeutics 2005;315(2):959-64.
2005: M Imad Damaj; Jenny L Wiley; Billy R Martin; Roger L Papke
In vivo characterization of a novel inhibitor of CNS nicotinic receptors.
European journal of pharmacology 2005;521(1-3):43-8.
2005: Malgorzata Dukat; Anna Ramunno; Rita Banzi; M Imad Damaj; Billy Martin; Richard A Glennon
3-(2-Aminoethyl)pyridine analogs as alpha4beta2 nicotinic cholinergic receptor ligands.
Bioorganic & medicinal chemistry letters 2005;15(19):4308-12.
2005: Anna Ramunno; Malgorzata Dukat; Mase Lee; Richard Young; Mohamed El-Zahabi; M Imad Damaj; Billy Martin; Richard A Glennon
6-(2-Phenylethyl)nicotine: a novel nicotinic cholinergic receptor ligand.
Bioorganic & medicinal chemistry letters 2005;15(13):3237-40.
2005: Sheri D Grabus; Billy R Martin; Angela M Batman; Rachel F Tyndale; Edward Sellers; M Imad Damaj
Nicotine physical dependence and tolerance in the mouse following chronic oral administration.
Psychopharmacology 2005;178(2-3):183-92.
2005: Frank carroll; Wei Ma; Yasuno Yokota; Jeffrey R Lee; Lawrence E Brieaddy; Hernán A Navarro; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists.
Journal of medicinal chemistry 2005;48(4):1221-8.
2005: M Imad Damaj; P Flood; K K Ho; Everette L May; Billy R Martin
Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity.
The Journal of pharmacology and experimental therapeutics 2005;312(2):780-5.
2004: M Imad Damaj; Richard Hunter; Billy R Martin; Michael J Kuhar
Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice.
Brain research 2004;1024(1-2):146-9.
2004: M Imad Damaj; Frank carroll; J Brek Eaton; Hernán A Navarro; Bruce E Blough; Sadiq Mirza; Ronald J. Lukas; Billy R Martin
Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors.
Molecular pharmacology 2004;66(3):675-82.
2004: Frank carroll; Roy Ware; Lawrence E Brieaddy; Hernán A Navarro; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist.
Journal of medicinal chemistry 2004;47(18):4588-94.
2004: Malgorzata Dukat; Mohamed Taroua; Abdelaziz Dahdouh; Uma Siripurapu; M Imad Damaj; Billy R Martin; Richard A Glennon
(+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents.
Bioorganic & medicinal chemistry letters 2004;14(14):3651-4.
2004: Deniz Dogruer; Mase Lee; Malgorzata Dukat; M Imad Damaj; Billy R Martin; Richard A Glennon
3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors.
Bioorganic & medicinal chemistry letters 2004;14(2):523-6.
2003: M Imad Damaj; W Kao; Billy R Martin
Characterization of spontaneous and precipitated nicotine withdrawal in the mouse.
The Journal of pharmacology and experimental therapeutics 2003;307(2):526-34.
2003: M Imad Damaj; Billy R Martin; Michael J Kuhar
Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice.
Brain research 2003;983(1-2):233-6.
2003: Henry A Lester; Carlos Fonck; Andrew R Tapper; Sheri McKinney; M Imad Damaj; Seth A Balogh; Jeremy Owens; Jeanne M Wehner; Allan C Collins; Cesar Labarca
Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action.
Current opinion in drug discovery & development 2003;6(5):633-9.
2003: Carlos Fonck; Raad Nashmi; Purnima Deshpande; M Imad Damaj; Michael J Marks; Anett Riedel; Johannes Schwarz; Allan C Collins; Cesar Labarca; Henry A Lester
Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(7):2582-90.
2003: G Ferretti; Malgorzata Dukat; Mario Giannella; Alessandro Piergentili; Maria Pigini; Wilma Quaglia; M Imad Damaj; Billy R Martin; Richard A Glennon
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors.
Bioorganic & medicinal chemistry letters 2003;13(4):733-5.
2002: Malgorzata Dukat; Mohamed El-Zahabi; Giovanni Ferretti; M Imad Damaj; Billy R Martin; Richard Young; Richard A Glennon
(-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine.
Bioorganic & medicinal chemistry letters 2002;12(20):3005-7.
2002: Frank carroll; Jeffrey R Lee; Hernán A Navarro; Wei Ma; Lawrence E Brieaddy; Philip Abraham; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues.
Journal of medicinal chemistry 2002;45(21):4755-61.
2002: G Ferretti; Malgorzata Dukat; Mario Giannella; Alessandro Piergentili; Maria Pigini; Wilma Quaglia; M Imad Damaj; B R Martin; Richard A Glennon
Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding.
Journal of medicinal chemistry 2002;45(21):4724-31.
2002: Mase Lee; Malgorzata Dukat; Liang Liao; Dwight Flammia; M Imad Damaj; Billy Martin; Richard A Glennon
A comparison of the binding of three series of nicotinic ligands.
Bioorganic & medicinal chemistry letters 2002;12(15):1989-92.
2002: Jenny L Wiley; Kari L LaVecchia; Billy R Martin; M Imad Damaj
Nicotine-like discriminative stimulus effects of bupropion in rats.
Experimental and clinical psychopharmacology 2002;10(2):129-35.
2001: Frank carroll; Jeffrey R Lee; Hernán A Navarro; Lawrence E Brieaddy; Philip Abraham; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist.
Journal of medicinal chemistry 2001;44(24):4039-41.
2001: Frank carroll; F Liang; Hernán A Navarro; Lawrence E Brieaddy; Philip Abraham; M Imad Damaj; Billy R Martin
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues.
Journal of medicinal chemistry 2001;44(13):2229-37.
2001: M Imad Damaj
Influence of gender and sex hormones on nicotine acute pharmacological effects in mice.
The Journal of pharmacology and experimental therapeutics 2001;296(1):132-40.
2000: G Ferretti; Malgorzata Dukat; Mario Giannella; Alessandro Piergentili; Maria Pigini; Wilma Quaglia; M Imad Damaj; B R Martin; Richard A Glennon
Chain-lengthened and imidazoline analogues of nicotine.
Bioorganic & medicinal chemistry letters 2000;10(23):2665-8.
2000: M Imad Damaj; E M Meyer; Billy R Martin
The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model.
Neuropharmacology 2000;39(13):2785-91.
2000: JE Slemmer; Billy R Martin; M Imad Damaj
Bupropion is a nicotinic antagonist.
The Journal of pharmacology and experimental therapeutics 2000;295(1):321-7.
2000: M Imad Damaj
The involvement of spinal Ca(2+)/calmodulin-protein kinase II in nicotine-induced antinociception in mice.
European journal of pharmacology 2000;404(1-2):103-10.
1999: M Imad Damaj; W Glassco; Malgorzata Dukat; Billy R Martin
Pharmacological characterization of nicotine-induced seizures in mice.
The Journal of pharmacology and experimental therapeutics 1999;291(3):1284-91.
1999: M Imad Damaj; W Glassco; Mario D Aceto; Billy R Martin
Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist.
The Journal of pharmacology and experimental therapeutics 1999;291(1):390-8.
1999: D Flammia; Malgorzata Dukat; M Imad Damaj; B Martin; Richard A Glennon
Lobeline: structure-affinity investigation of nicotinic acetylcholinergic receptor binding.
Journal of medicinal chemistry 1999;42(18):3726-31.
1999: M Imad Damaj; JE Slemmer; Frank carroll; Billy R Martin
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1229-36.
1998: M Imad Damaj; M Fei-Yin; Malgorzata Dukat; W Glassco; Richard A Glennon; Billy R Martin
Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice.
The Journal of pharmacology and experimental therapeutics 1998;284(3):1058-65.
1997: M Imad Damaj; W Glassco; Michael J Marks; BS Slobe; John R James; Everette L May; John A Rosecrans; Allan C Collins; Billy R Martin
Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1425-34.
1997: M Imad Damaj; GS Patrick; K R Creasy; Billy R Martin
Pharmacology of lobeline, a nicotinic receptor ligand.
The Journal of pharmacology and experimental therapeutics 1997;282(1):410-9.
1997: M Imad Damaj
Altered behavioral sensitivity of Ca(2+)-modulating drugs after chronic nicotine administration in mice.
European journal of pharmacology 1997;322(2-3):129-35.
1996: M Imad Damaj; Billy R Martin
Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice.
European journal of pharmacology 1996;300(1-2):51-7.
1996: M Imad Damaj; Sandra P Welch; Billy R Martin
Characterization and modulation of acute tolerance to nicotine in mice.
The Journal of pharmacology and experimental therapeutics 1996;277(1):454-61.
1995: M Imad Damaj; K R Creasy; Sandra P Welch; John A Rosecrans; Mario D Aceto; Billy R Martin
Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist.
Psychopharmacology 1995;120(4):483-90.
1995: M Imad Damaj; Sandra P Welch; Billy R Martin
In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice.
Psychopharmacology 1995;117(1):67-73.
1994: M Imad Damaj; K R Creasy; A D Grove; John A Rosecrans; Billy R Martin
Pharmacological effects of epibatidine optical enantiomers.
Brain research 1994;664(1-2):34-40.
1994: M Imad Damaj; Sandra P Welch; Billy R Martin
Nicotine-induced antinociception in mice: role of G-proteins and adenylate cyclase.
Pharmacology, biochemistry, and behavior 1994;48(1):37-42.
1994: M Imad Damaj; Richard A Glennon; Billy R Martin
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice.
Brain research bulletin 1994;33(2):199-203.
1993: M Imad Damaj; Sandra P Welch; Billy R Martin
Involvement of calcium and L-type channels in nicotine-induced antinociception.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1330-8.
1993: M Imad Damaj; Billy R Martin
Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility.
Drug and alcohol dependence 1993;32(1):73-9.
1993: M Imad Damaj; Billy R Martin
Is the dopaminergic system involved in the central effects of nicotine in mice?
Psychopharmacology 1993;111(1):106-8.