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Imad Damaj

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
42
Martin, Billy
12
Dukat, Malgorzata
12
Glennon, Richard
11
Navarro, Hernán
11
carroll, Frank
9
Martin, Billy
8
Brieaddy, Lawrence
5
Collins, Allan
5
Welch, Sandra
4
Abraham, Philip
4
Lee, Jeffrey
4
Ma, Wei
4
Marks, Michael
4
Martin, Billy
4
Glassco, W

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Publications

TOP 3
Jackson K J; McIntosh J M; Brunzell D H; Sanjakdar S S; Damaj M I
The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal.
Jackson Kia J; Walters Carrie L; Miles Michael F; Martin Billy R; Damaj M Imad
Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice.
Jackson K J; Walters C L; Damaj M I
Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo.

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All Publications

2009: Jackson K J; McIntosh J M; Brunzell D H; Sanjakdar S S; Damaj M I
The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal.
The Journal of pharmacology and experimental therapeutics 2009;331(2):547-54.
2009: Jackson Kia J; Walters Carrie L; Miles Michael F; Martin Billy R; Damaj M Imad
Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice.
Neuropharmacology 2009;57(4):347-55.
2009: Jackson K J; Walters C L; Damaj M I
Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo.
The Journal of pharmacology and experimental therapeutics 2009;330(2):541-9.
2009: Jackson K J; Damaj M I
L-type calcium channels and calcium/calmodulin-dependent kinase II differentially mediate behaviors associated with nicotine withdrawal in mice.
The Journal of pharmacology and experimental therapeutics 2009;330(1):152-61.
2009: Jackson K J; Kota D H; Martin B R; Damaj M I
The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion.
Neuropharmacology 2009;56(6-7):970-4.
2008: Abdrakhmanova Galya R; Carroll F Ivy; Damaj M I; Martin Billy R
3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs.
Neuropharmacology 2008;55(8):1287-92.
2008: Merritt Lisa L; Martin B R; Walters C; Lichtman A H; Damaj M Imad
The endogenous cannabinoid system modulates nicotine reward and dependence.
The Journal of pharmacology and experimental therapeutics 2008;326(2):483-92.
2008: Kota D; Martin B R; Damaj M I
Age-dependent differences in nicotine reward and withdrawal in female mice.
Psychopharmacology 2008;198(2):201-10.
2008: Jackson K J; Martin B R; Changeux J P; Damaj M I
Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs.
The Journal of pharmacology and experimental therapeutics 2008;325(1):302-12.
2008: Ivy Carroll F; Yokota Yasuno; Ma Wei; Lee Jeffrey R; Brieaddy Lawrence E; Burgess Jason P; Navarro Hernán A; Damaj M I; Martin Billy R
Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs.
Bioorganic & medicinal chemistry 2008;16(2):746-54.
2007: Carroll F Ivy; Robinson T Philip; Brieaddy Lawrence E; Atkinson Robert N; Mascarella S Wayne; Damaj M Imad; Martin Billy R; Navarro Hernán A
Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine.
Journal of medicinal chemistry 2007;50(25):6383-91.
2007: Damaj M Imad
Behavioral modulation of neuronal calcium/calmodulin-dependent protein kinase II activity: differential effects on nicotine-induced spinal and supraspinal antinociception in mice.
Biochemical pharmacology 2007;74(8):1247-52.
2007: Kota D; Martin B R; Robinson S E; Damaj M I
Nicotine dependence and reward differ between adolescent and adult male mice.
The Journal of pharmacology and experimental therapeutics 2007;322(1):399-407.
2007: Hansen Henrik H; Timmermann Daniel B; Peters Dan; Walters Carrie; Damaj M Imad; Mikkelsen Jens D
Alpha-7 nicotinic acetylcholine receptor agonists selectively activate limbic regions of the rat forebrain: an effect similar to antipsychotics.
Journal of neuroscience research 2007;85(8):1810-8.
2007: Damaj M I; Fonck C; Marks M J; Deshpande P; Labarca C; Lester H A; Collins A C; Martin B R
Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice.
The Journal of pharmacology and experimental therapeutics 2007;321(3):1161-9.
2007: Matta Shannon G; Balfour David J; Benowitz Neal L; Boyd R Thomas; Buccafusco Jerry J; Caggiula Anthony R; Craig Caroline R; Collins Allan C; Damaj M Imad; Donny Eric C; Gardiner Phillip S; Grady Sharon R; Heberlein Ulrike; Leonard Sherry S; Levin Edward D; Lukas Ronald J; Markou Athina; Marks Michael J; McCallum Sarah E; Parameswaran Neeraja; Perkins Kenneth A; Picciotto Marina R; Quik Maryka; Rose Jed E; Rothenfluh Adrian; Schafer William R; Stolerman Ian P; Tyndale Rachel F; Wehner Jeanne M; Zirger Jeffrey M
Guidelines on nicotine dose selection for in vivo research.
Psychopharmacology 2007;190(3):269-319.
2007: Ivy Carroll F; Ma Wei; Navarro Hernán A; Abraham Philip; Wolckenhauer Scott A; Damaj M I; Martin Billy R
Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.
Bioorganic & medicinal chemistry 2007;15(2):678-85.
2007: Damaj M I
Nicotinic regulation of calcium/calmodulin-dependent protein kinase II activation in the spinal cord.
The Journal of pharmacology and experimental therapeutics 2007;320(1):244-9.
2007: Damaj M I; Siu E C K; Sellers E M; Tyndale R F; Martin B R
Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice.
The Journal of pharmacology and experimental therapeutics 2007;320(1):250-7.
2006: Wright M Jerry; Vann Robert E; Gamage Thomas F; Damaj M Imad; Wiley Jenny L
Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats.
Pharmacology, biochemistry, and behavior 2006;85(3):507-13.
2006: Damaj M Imad; Zheng Jianfeng; Martin Billy R; Kuhar Michael J
Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain.
Peptides 2006;27(8):2019-23.
2006: Carroll F Ivy; Hu Xingding; Navarro Hernán A; Deschamps Jeffrey; Abdrakhmanova Galya R; Damaj M Imad; Martin Billy R
Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes.
Journal of medicinal chemistry 2006;49(11):3244-50.
2006: Abdrakhmanova Galya R; Damaj M Imad; Carroll F Ivy; Martin Billy R
2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs.
Molecular pharmacology 2006;69(6):1945-52.
2006: Grabus Sheri D; Martin Billy R; Brown Sharon E; Damaj M Imad
Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists.
Psychopharmacology 2006;184(3-4):456-63.
2006: Walters Carrie L; Brown Sharon; Changeux Jean-Pierre; Martin Billy; Damaj M Imad
The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice.
Psychopharmacology 2006;184(3-4):339-44.
2005: Carroll F Ivy; Brieaddy Lawrence E; Navarro Hernán A; Damaj M I; Martin Billy R
Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues.
Journal of medicinal chemistry 2005;48(23):7491-5.
2005: Damaj M I
Calcium-acting drugs modulate expression and development of chronic tolerance to nicotine-induced antinociception in mice.
The Journal of pharmacology and experimental therapeutics 2005;315(2):959-64.
2005: Damaj M Imad; Wiley Jenny L; Martin Billy R; Papke Roger L
In vivo characterization of a novel inhibitor of CNS nicotinic receptors.
European journal of pharmacology 2005;521(1-3):43-8.
2005: Dukat Malgorzata; Ramunno Anna; Banzi Rita; Damaj M Imad; Martin Billy; Glennon Richard A
3-(2-Aminoethyl)pyridine analogs as alpha4beta2 nicotinic cholinergic receptor ligands.
Bioorganic & medicinal chemistry letters 2005;15(19):4308-12.
2005: Ramunno Anna; Dukat Malgorzata; Lee Mase; Young Richard; El-Zahabi Mohamed; Damaj M Imad; Martin Billy; Glennon Richard A
6-(2-Phenylethyl)nicotine: a novel nicotinic cholinergic receptor ligand.
Bioorganic & medicinal chemistry letters 2005;15(13):3237-40.
2005: Grabus Sheri D; Martin Billy R; Batman Angela M; Tyndale Rachel F; Sellers Edward; Damaj M Imad
Nicotine physical dependence and tolerance in the mouse following chronic oral administration.
Psychopharmacology 2005;178(2-3):183-92.
2005: Carroll F Ivy; Ma Wei; Yokota Yasuno; Lee Jeffrey R; Brieaddy Lawrence E; Navarro Hernán A; Damaj M I; Martin Billy R
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists.
Journal of medicinal chemistry 2005;48(4):1221-8.
2005: Damaj M I; Flood P; Ho K K; May E L; Martin B R
Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity.
The Journal of pharmacology and experimental therapeutics 2005;312(2):780-5.
2004: Damaj M Imad; Hunter Richard G; Martin Billy R; Kuhar Michael J
Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice.
Brain research 2004;1024(1-2):146-9.
2004: Damaj M Imad; Carroll F Ivy; Eaton J Brek; Navarro Hernan A; Blough Bruce E; Mirza Sadiq; Lukas Ronald J; Martin Billy R
Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors.
Molecular pharmacology 2004;66(3):675-82.
2004: Carroll F Ivy; Ware Roy; Brieaddy Lawrence E; Navarro Hernán A; Damaj M I; Martin Billy R
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist.
Journal of medicinal chemistry 2004;47(18):4588-94.
2004: Dukat Malgorzata; Taroua Mohamed; Dahdouh Abdelaziz; Siripurapu Umamaheswar; Damaj M Imad; Martin Billy R; Glennon Richard A
(+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents.
Bioorganic & medicinal chemistry letters 2004;14(14):3651-4.
2004: Dogruer Deniz; Lee Mase; Dukat Malgorzata; Damaj M Imad; Martin Billy R; Glennon Richard A
3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors.
Bioorganic & medicinal chemistry letters 2004;14(2):523-6.
2003: Damaj M I; Kao W; Martin B R
Characterization of spontaneous and precipitated nicotine withdrawal in the mouse.
The Journal of pharmacology and experimental therapeutics 2003;307(2):526-34.
2003: Lester Henry A; Fonck Carlos; Tapper Andrew R; McKinney Sheri; Damaj M Imad; Balogh Seth; Owens Jeremy; Wehner Jeanne M; Collins Allan C; Labarca Cesar
Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action.
Current opinion in drug discovery & development 2003;6(5):633-9.
2003: Damaj M Imad; Martin Billy R; Kuhar Michael J
Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice.
Brain research 2003;983(1-2):233-6.
2003: Fonck Carlos; Nashmi Raad; Deshpande Purnima; Damaj M Imad; Marks Michael J; Riedel Anett; Schwarz Johannes; Collins Allan C; Labarca Cesar; Lester Henry A
Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(7):2582-90.
2003: Ferretti G; Dukat M; Giannella M; Piergentili A; Pigini M; Quaglia W; Damaj M I; Martin B R; Glennon R A
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors.
Bioorganic & medicinal chemistry letters 2003;13(4):733-5.
2002: Carroll F Ivy; Lee Jeffrey R; Navarro Hernán A; Ma Wei; Brieaddy Lawrence E; Abraham Philip; Damaj M I; Martin Billy R
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues.
Journal of medicinal chemistry 2002;45(21):4755-61.
2002: Ferretti G; Dukat M; Giannella M; Piergentili A; Pigini M; Quaglia W; Damaj M I; Martin B R; Glennon R A
Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding.
Journal of medicinal chemistry 2002;45(21):4724-31.
2002: Dukat Malgorzata; El-Zahabi Mohamed; Ferretti Giovanni; Damaj M Imad; Martin Billy R; Young Richard; Glennon Richard A
(-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine.
Bioorganic & medicinal chemistry letters 2002;12(20):3005-7.
2002: Lee Mase; Dukat Malgorzata; Liao Liang; Flammia Dwight; Damaj M Imad; Martin Billy; Glennon Richard A
A comparison of the binding of three series of nicotinic ligands.
Bioorganic & medicinal chemistry letters 2002;12(15):1989-92.
2002: Wiley Jenny L; Lavecchia Kari L; Martin Billy R; Damaj M Imad
Nicotine-like discriminative stimulus effects of bupropion in rats.
Experimental and clinical psychopharmacology 2002;10(2):129-35.
2001: Carroll F I; Lee J R; Navarro H A; Brieaddy L E; Abraham P; Damaj M I; Martin B R
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist.
Journal of medicinal chemistry 2001;44(24):4039-41.
2001: Carroll F I; Liang F; Navarro H A; Brieaddy L E; Abraham P; Damaj M I; Martin B R
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues.
Journal of medicinal chemistry 2001;44(13):2229-37.
2001: Damaj M I
Influence of gender and sex hormones on nicotine acute pharmacological effects in mice.
The Journal of pharmacology and experimental therapeutics 2001;296(1):132-40.
2000: Ferretti G; Dukat M; Giannella M; Piergentili A; Pigini M; Quaglia W; Damaj M I; Martin B R; Glennon R A
Chain-lengthened and imidazoline analogues of nicotine.
Bioorganic & medicinal chemistry letters 2000;10(23):2665-8.
2000: Damaj M I; Meyer E M; Martin B R
The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model.
Neuropharmacology 2000;39(13):2785-91.
2000: Slemmer J E; Martin B R; Damaj M I
Bupropion is a nicotinic antagonist.
The Journal of pharmacology and experimental therapeutics 2000;295(1):321-7.
2000: Damaj M I
The involvement of spinal Ca(2+)/calmodulin-protein kinase II in nicotine-induced antinociception in mice.
European journal of pharmacology 2000;404(1-2):103-10.
1999: Damaj M I; Glassco W; Dukat M; Martin B R
Pharmacological characterization of nicotine-induced seizures in mice.
The Journal of pharmacology and experimental therapeutics 1999;291(3):1284-91.
1999: Damaj M I; Glassco W; Aceto M D; Martin B R
Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist.
The Journal of pharmacology and experimental therapeutics 1999;291(1):390-8.
1999: Flammia D; Dukat M; Damaj M I; Martin B; Glennon R A
Lobeline: structure-affinity investigation of nicotinic acetylcholinergic receptor binding.
Journal of medicinal chemistry 1999;42(18):3726-31.
1999: Damaj M I; Slemmer J E; Carroll F I; Martin B R
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1229-36.
1998: Damaj M I; Fei-Yin M; Dukat M; Glassco W; Glennon R A; Martin B R
Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice.
The Journal of pharmacology and experimental therapeutics 1998;284(3):1058-65.
1997: Damaj M I; Glassco W; Marks M J; Slobe B; James J R; May E L; Rosecrans J A; Collins A C; Martin B R
Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1425-34.
1997: Damaj M I; Patrick G S; Creasy K R; Martin B R
Pharmacology of lobeline, a nicotinic receptor ligand.
The Journal of pharmacology and experimental therapeutics 1997;282(1):410-9.
1997: Damaj M I
Altered behavioral sensitivity of Ca(2+)-modulating drugs after chronic nicotine administration in mice.
European journal of pharmacology 1997;322(2-3):129-35.
1996: Damaj M I; Martin B R
Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice.
European journal of pharmacology 1996;300(1-2):51-7.
1996: Damaj M I; Welch S P; Martin B R
Characterization and modulation of acute tolerance to nicotine in mice.
The Journal of pharmacology and experimental therapeutics 1996;277(1):454-61.
1995: Damaj M I; Creasy K R; Welch S P; Rosecrans J A; Aceto M D; Martin B R
Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist.
Psychopharmacology 1995;120(4):483-90.
1995: Damaj M I; Welch S P; Martin B R
In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice.
Psychopharmacology 1995;117(1):67-73.
1994: Damaj M I; Creasy K R; Grove A D; Rosecrans J A; Martin B R
Pharmacological effects of epibatidine optical enantiomers.
Brain research 1994;664(1-2):34-40.
1994: Damaj M I; Welch S P; Martin B R
Nicotine-induced antinociception in mice: role of G-proteins and adenylate cyclase.
Pharmacology, biochemistry, and behavior 1994;48(1):37-42.
1994: Damaj M I; Glennon R A; Martin B R
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice.
Brain research bulletin 1994;33(2):199-203.
1993: Damaj M I; Welch S P; Martin B R
Involvement of calcium and L-type channels in nicotine-induced antinociception.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1330-8.
1993: Damaj M I; Martin B R
Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility.
Drug and alcohol dependence 1993;32(1):73-9.
1993: Damaj M I; Martin B R
Is the dopaminergic system involved in the central effects of nicotine in mice?
Psychopharmacology 1993;111(1):106-8.

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