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Lyaquat Damani

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Living Beings

Phenomena

Oxidation-Reduction

Chemicals & Drugs

Physiology

Biotransformation

Anatomy

Liver Microsomes

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Co-Publications
Name
9
Crooks, Peter
9
Nnane, Ivo
8
Lin, Ge
5
Hutt, Andrew
4
Hider, Robert
3
Mitterhauser, M
3
Camilleri, Patrick
3
Zolle, I
2
Jakoby, WB
1
Kadaba, PK
1
Li, Ronald
1
Porter, John
1
Wedlund, Peter
1
Yokel, Robert

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Publications

TOP 3
Nnane Ivo P; Damani Lyaquat A
Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.
Nnane Ivo P; Damani Lyaquat A
Involvement of cytochrome P450 and the flavin-containing monooxygenase(s) in the sulphoxidation of simple sulphides in human liver microsomes.
Nnane I P; Damani L A
Sulphoxidation of ethyl methyl sulphide, 4-chlorophenyl methyl sulphide and diphenyl sulphide by purified pig liver flavin-containing monooxygenase.

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All Publications

2005: Nnane Ivo P; Damani Lyaquat A
Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.
Biomedical chromatography : BMC 2005;19(1):87-98.
2003: Nnane Ivo P; Damani Lyaquat A
Involvement of cytochrome P450 and the flavin-containing monooxygenase(s) in the sulphoxidation of simple sulphides in human liver microsomes.
Life sciences 2003;73(3):359-69.
2003: Nnane I P; Damani L A
Sulphoxidation of ethyl methyl sulphide, 4-chlorophenyl methyl sulphide and diphenyl sulphide by purified pig liver flavin-containing monooxygenase.
Xenobiotica; the fate of foreign compounds in biological systems 2003;33(1):83-91.
2002: Nnane Ivo P; Damani Lyaquatali A
HPLC analysis of 4-chlorophenyl methyl sulphide and diphenyl sulphide and their corresponding sulphoxides and sulphones in rat liver microsomes.
Journal of pharmaceutical and biomedical analysis 2002;27(1-2):315-25.
2001: Nnane I P; Damani L A
Pharmacokinetics of trimethylamine in rats, including the effects of a synthetic diet.
Xenobiotica; the fate of foreign compounds in biological systems 2001;31(10):749-55.
2001: Nnane L P; Damani L A; Hutt A J
The effects of a synthetic diet on the pharmacokinetics of ethyl methyl sulphide and its sulphoxide and sulphone metabolites in rats.
European journal of drug metabolism and pharmacokinetics 2001;26(1-2):17-24.
2000: Lee C W; Tomlinson B; Yeung J H; Lin G; Damani L A
Distribution of the N-oxidation of dietary-derived trimethylamine in a male Chinese population.
Pharmacogenetics 2000;10(9):829-31.
1999: Nnane I P; Damani L A
Metabolism of ethyl methyl sulphide and sulphoxide in rat microsomal fractions.
Xenobiotica; the fate of foreign compounds in biological systems 1999;29(11):1101-13.
1999: Nnane I P; Tsai M C; Lin G; Damani L A; Mitterhauser M; Zolle I
Pharmacokinetics of 2-methoxyphenylmetyrapone and 2-bromophenylmetyrapone in rats.
European journal of drug metabolism and pharmacokinetics 1999;24(1):23-9.
1998: Lin G; Nnane I P; Damani L A; Tse K K; Chow A H; Kadaba P K
High performance liquid chromatographic analysis of a novel aminoalkylpyridine anticonvulsant 2-(4-chlorophenyl)amino-2-(4-pyridyl)ethane.
Journal of pharmaceutical and biomedical analysis 1998;18(3):403-9.
1997: Damani L A; Tsai M C; Lin G; Mitterhauser M; Zolle I
Simultaneous analysis of 2-methoxyphenylmetyrapone and its seven potential metabolites by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1997;704(1-2):315-23.
1997: Chiu F C; Damani L A; Li R C; Tomlinson B
Efficient high-performance liquid chromatographic assay for the simultaneous determination of metoprolol and two main metabolites in human urine by solid-phase extraction and fluorescence detection.
Journal of chromatography. B, Biomedical sciences and applications 1997;696(1):69-74.
1997: Ho Y P; Lin G; Damani L A; Mitterhauser M; Zolle I
Spectral and chromatographic properties of 2-methoxyphenylmetyrapone and its potential metabolites.
Journal of pharmaceutical and biomedical analysis 1997;15(4):479-86.
1996: Lin G; Chu K W; Damani L A; Hawes E M; Midha K K
Identification of lactams as in vitro metabolites of piperidine-type phenothiazine antipsychotic drugs.
Journal of pharmaceutical and biomedical analysis 1996;14(6):727-38.
1996: Damani L A; Mitterhauser M; Lin G; Ho Y P; Zolle I
Urinary metabolic profile in rat of 1-(2-methoxyphenyl)-2-methyl-2-(3-pyridyl)-1-propanone: a potential radioligand for functional diagnosis of adrenal pathology.
Xenobiotica; the fate of foreign compounds in biological systems 1996;26(2):211-19.
1996: Kadaba P K; Stevenson P J; P-Nnane I; Damani L A
Triazolines--XXVII. delta2-1,2,3-triazoline anticonvulsants: novel 'built-in' heterocyclic prodrugs with a unique 'dual-action' mechanism for impairing excitatory amino acid L-glutamate neurotransmission.
Bioorganic & medicinal chemistry 1996;4(2):165-78.
1996: Chow A H; Chiu F C; Damani L A; Kadaba P K
Triazolines. 34. Structure and stability relationships of novel delta 2-1,2,3-triazoline anticonvulsants.
Pharmaceutical research 1996;13(1):179-82.
1996: Hadley M R; Oldham H G; Camilleri P; Damani L A; Hutt A J
Species differences in the stereoselectivity of N-oxygenation of N-ethyl-N-methylaniline in vitro.
Chirality 1996;8(6):430-40.
1996: Damani L A; Nnane I P
The assessment of flavin-containing monooxygenase activity in intact animals.
Drug metabolism and drug interactions 1996;13(1):1-28.
1995: Damani L A; Mitterhauser M; Zolle I; Lin G; Oehler E; Ho Y P
Metabolic and pharmacokinetic considerations in the design of 2-phenyl substituted metyrapone derivatives: 2-methoxyphenylmetyrapone as a radioligand for functional diagnosis of adrenal pathology.
Nuclear medicine and biology 1995;22(8):1067-74.
1994: Epemolu R O; Ackerman R; Porter J B; Hider R C; Damani L A; Singh S
HPLC determination of 1,2-diethyl-3-hydroxypyridin-4-one (CP94), its iron complex [Fe(III) (CP94)3] and glucuronide conjugate [CP94-GLUC] in serum and urine of thalassaemic patients.
Journal of pharmaceutical and biomedical analysis 1994;12(7):923-30.
1994: Hadley M R; Oldham H G; Damani L A; Hutt A J
Asymmetric metabolic N-oxidation of N-ethyl-N-methylaniline by purified flavin-containing monooxygenase.
Chirality 1994;6(2):98-104.
1994: Hadley M R; Svajdlenka E; Damani L A; Oldham H G; Tribe J; Camilleri P; Hutt A J
Species variability in the stereoselective N-oxidation of pargyline.
Chirality 1994;6(2):91-7.
1993: Hadley M R; Oldham H G; Camilleri P; Murphy J; Hutt A J; Damani L A
Stereoselective microsomal N-oxidation of N-ethyl-N-methylaniline.
Biochemical pharmacology 1993;45(9):1739-42.
1993: On N T; Damani L A; Rance D J
A sensitive high-performance liquid chromatographic determination of 6-(pyridin-3-yl)-quinolin-2(1H)-one and its N-oxide metabolite in rat plasma and urine.
Journal of pharmaceutical and biomedical analysis 1993;11(4-5):421-5.
1993: Fredenburg A M; Wedlund P J; Skinner T L; Damani L A; Hider R C; Yokel R A
Pharmacokinetics of representative 3-hydroxypyridin-4-ones in rabbits: CP20 and CP94.
Drug metabolism and disposition: the biological fate of chemicals 1993;21(2):255-8.
1992: Epemolu O R; Singh S; Hider R C; Damani L A
The pharmacokinetics of 1,2-diethyl-3-hydroxypyridin-4-one (CP94) in rats.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(5):736-41.
1992: Freeke Hamelijnck M A; Stevenson P J; Kadaba P K; Damani L A
Triazolines. XXI: Preformulation degradation kinetics and chemical stability of a novel triazoline anticonvulsant.
Journal of pharmaceutical sciences 1992;81(4):392-6.
1992: Singh S; Epemolu R O; Dobbin P S; Tilbrook G S; Ellis B L; Damani L A; Hider R C
Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(2):256-61.
1992: On N T; Damani L A; Rance D J
Quantitation of 6-(pyridin-3-yl)quinolin-2(1H)-one, a cardiac stimulant, and its N-oxide metabolite in dog plasma by high-performance liquid chromatography.
Journal of chromatography 1992;574(2):352-5.
1992: Epemolu R O; Singh S; Hider R C; Damani L A
High-performance liquid chromatographic determination of 1,2-diethyl-3-hydroxypyridin-4-one and its 2-(1-hydroxyethyl) metabolite in rat blood.
Journal of chromatography 1992;573(1):178-82.
1991: Stevenson P J; Hamelijnck M A; Kadaba P K; Damani L A
Triazolines. XXIII. High-performance liquid chromatographic assay in rat blood for a novel triazoline anticonvulsant (ADD17014).
Journal of chromatography 1991;563(2):419-26.
1990: Stevenson P J; Hauksdottir R; Kadaba P K; Damani L A
Triazolines. XXII. Chromatography of 1-phenyl-5-(4-pyridyl)-delta 2-1,2,3-triazolines and related 1,2,3-triazoles, a new class of anticonvulsant agents.
Journal of chromatography 1990;533():248-54.
1988: Nwosu C G; Godin C S; Houdi A A; Damani L A; Crooks P A
Enantioselective metabolism during continuous administration of S-(-)- and R-(+)-nicotine isomers to guinea-pigs.
The Journal of pharmacy and pharmacology 1988;40(12):862-9.
1988: Damani L A; Pool W F; Crooks P A; Kaderlik R K; Ziegler D M
Stereoselectivity in the N'-oxidation of nicotine isomers by flavin-containing monooxygenase.
Molecular pharmacology 1988;33(6):702-5.
1988: Crooks P A; Godin C S; Damani L A; Ansher S S; Jakoby W B
Formation of quaternary amines by N-methylation of azaheterocycles with homogeneous amine N-methyltransferases.
Biochemical pharmacology 1988;37(9):1673-7.
1988: Damani L A
Chemical reactivity considerations in the metabolism of N-heteroaromatics.
Drug metabolism and drug interactions 1988;6(2):149-58.
1988: Damani L A; Houdi A A
Cytochrome P-450 and FAD-monooxygenase mediated S- and N-oxygenations.
Drug metabolism and drug interactions 1988;6(3-4):235-44.
1986: Godin C S; Crooks P A; Damani L A
N-methylation of phenylpyridines and bispyridyls as a potential toxication route: tissue distribution of azaheterocycle N-methyltransferase activity in the rabbit.
Toxicology letters 1986;34(2-3):217-22.
1986: Pool W F; Houdi A A; Damani L A; Layton W J; Crooks P A
Isolation and characterization of N-methyl-N'-oxonicotinium ion, a new urinary metabolite of R-(+)-nicotine in the guinea pig.
Drug metabolism and disposition: the biological fate of chemicals 1986;14(5):574-9.
1986: Damani L A; Shaker M S; Crooks P A; Godin C S; Nwosu C
N-methylation and quaternization of pyridine in vitro by rabbit lung, liver and kidney N-methyltransferases: an S-adenosyl-L-methionine-dependent reaction.
Xenobiotica; the fate of foreign compounds in biological systems 1986;16(7):645-50.
1986: Damani L A; Shaker M S; Godin C S; Crooks P A; Ansher S S; Jakoby W B
The ability of amine N-methyltransferases from rabbit liver to N-methylate azaheterocycles.
The Journal of pharmacy and pharmacology 1986;38(7):547-50.
1982: Damani L A; Crooks P A; Shaker M S; Caldwell J; D'Souza J; Smith R L
Species differences in the metabolic C- and N-oxidation , and N-methylation of [14C]pyridine in vivo.
Xenobiotica; the fate of foreign compounds in biological systems 1982;12(8):527-34.
1982: Shaker M S; Crooks P A; Damani L A
High-performance liquid chromatographic analysis of the in vivo metabolites of [14C]pyridine.
Journal of chromatography 1982;237(3):489-95.

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