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Masad Damha

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Nerea Martín-Pintado; Modesto Orozco; Guillem Portella; Maryam Yahyaee-Anzahaee; Masad J Damha; Glen F Deleavey; Carlos González
Dramatic effect of furanose c2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom.
Glen F Deleavey; Filipp Frank; Matthew Hassler; Bhushan Nagar; Simon Wisnovsky; Masad J Damha
The 5' binding MID domain of human Argonaute2 tolerates chemically modified nucleotide analogues.
Nerea Martín-Pintado; Anne M Noronha; Christopher J Wilds; Maryam Yahyaee-Anzahaee; Ramón Campos-Olivas; Masad J Damha; Carlos González
The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion.

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2013: Nerea Martín-Pintado; Modesto Orozco; Guillem Portella; Maryam Yahyaee-Anzahaee; Masad J Damha; Glen F Deleavey; Carlos González
Dramatic effect of furanose c2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom.
Journal of the American Chemical Society 2013;135(14):5344-7.
2013: Glen F Deleavey; Filipp Frank; Matthew Hassler; Bhushan Nagar; Simon Wisnovsky; Masad J Damha
The 5' binding MID domain of human Argonaute2 tolerates chemically modified nucleotide analogues.
Nucleic acid therapeutics 2013;23(1):81-7.
2012: Nerea Martín-Pintado; Anne M Noronha; Christopher J Wilds; Maryam Yahyaee-Anzahaee; Ramón Campos-Olivas; Masad J Damha; Carlos González
The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion.
Nucleic acids research 2012;40(18):9329-39.
2012: Arnaud E Felber; Núria Bayó-Puxan; Bastien Castagner; Masad J Damha; Glen F Deleavey; Jean-Christophe Leroux
The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity.
Biomaterials 2012;33(25):5955-65.
2012: Glen F Deleavey; Masad J Damha
Designing chemically modified oligonucleotides for targeted gene silencing.
Chemistry & biology 2012;19(8):937-54.
2012: Naira Souleimanian; Masad J Damha; Glen F Deleavey; Harris S Soifer; Katrin Tiemann; Sijian Wang; Cy A Stein
Antisense 2'-Deoxy, 2'-Fluroarabino Nucleic Acids (2'F-ANAs) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids.
Molecular therapy. Nucleic acids 2012;1():e43.
2011: Alexander S Wahba; Fereshteh Azizi; Claire Brown; Marilyn Carrier; Glen F Deleavey; Alan M Gewirtz; Robert H E Hudson; Anna Kalota; Jerry Pelletier; Francis Robert; Masad J Damha
Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA.
ACS chemical biology 2011;6(9):912-9.
2011: Richard Johnsson; Jeremy G Lackey; Jovanka J Bogojeski; Masad J Damha
New light labile linker for solid phase synthesis of 2'-O-acetalester oligonucleotides and applications to siRNA prodrug development.
Bioorganic & medicinal chemistry letters 2011;21(12):3721-5.
2011: Arnaud E Felber; Bastien Castagner; Masad J Damha; Glen F Deleavey; Mahmoud Elsabahy; Jean-Christophe Leroux
siRNA nanocarriers based on methacrylic acid copolymers.
Journal of controlled release : official journal of the Controlled Release Society 2011;152(1):159-67.
2011: Maryam Yahyaee Anzahaee; Jonathan K Watts; Nageswara R Alla; Allen W Nicholson; Masad J Damha
Energetically important C-H···F-C pseudohydrogen bonding in water: evidence and application to rational design of oligonucleotides with high binding affinity.
Journal of the American Chemical Society 2011;133(4):728-31.
2010: Keith T Gagnon; Hannah M Pendergraff; Glen F Deleavey; Eric E Swayze; Pierre Potier; John Randolph; Eric B Roesch; Jyoti Chattopadhyaya; Masad J Damha; C Frank Bennett; Christophe Montaillier; Marc Lemaitre; David R Corey
Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat.
Biochemistry 2010;49(47):10166-78.
2010: Glen F Deleavey; Jonathan K Watts; Tommy Alain; Francis Robert; Anna Kalota; Veenu Aishwarya; Jerry Pelletier; Alan M Gewirtz; Nahum Sonenberg; Masad J Damha
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing.
Nucleic acids research 2010;38(13):4547-57.
2010: Jonathan K Watts; Nerea Martín-Pintado; Irene Gómez-Pinto; Jeremy Schwartzentruber; Guillem Portella; Modesto Orozco; Carlos González; Masad J Damha
Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility.
Nucleic acids research 2010;38(7):2498-511.
2010: Alexander S Wahba; Abbasali Esmaeili; Masad J Damha; Robert H E Hudson
A single-label phenylpyrrolocytidine provides a molecular beacon-like response reporting HIV-1 RT RNase H activity.
Nucleic acids research 2010;38(3):1048-56.
2009: Glen F Deleavey; Jonathan K Watts; Masad J Damha
Chemical modification of siRNA.
Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2009;Chapter 16():Unit 16.3.
2009: Jeremy G Lackey; Debbie Mitra; Mark M Somoza; Franco Cerrina; Masad J Damha
Acetal levulinyl ester (ALE) groups for 2'-hydroxyl protection of ribonucleosides in the synthesis of oligoribonucleotides on glass and microarrays.
Journal of the American Chemical Society 2009;131(24):8496-502.
2009: Jonathan K Watts; Adam Katolik; Julia Viladoms; Masad J Damha
Studies on the hydrolytic stability of 2'-fluoroarabinonucleic acid (2'F-ANA).
Organic & biomolecular chemistry 2009;7(9):1904-10.
2008: Jonathan K Watts; Glen F Deleavey; Masad J Damha
Chemically modified siRNA: tools and applications.
Drug discovery today 2008;13(19-20):842-55.
2008: Jonathan K Watts; Blair D Johnston; Kumarasamy Jayakanthan; Alexander S Wahba; B Mario Pinto; Masad J Damha
Synthesis and biophysical characterization of oligonucleotides containing a 4'-selenonucleotide.
Journal of the American Chemical Society 2008;130(27):8578-9.
2008: Heather P Harding; Jeremy G Lackey; Hao-Chi Hsu; Yuhong Zhang; Jing Deng; Rui-Ming Xu; Masad J Damha; David Ron
An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation.
RNA (New York, N.Y.) 2008;14(2):225-32.
2008: Jeremy G Lackey; David Ron; Masad J Damha; Heather P Harding
Toward the discovery of new antifungal agents: the design and validation of a novel 2'P-RNA probe and high throughput screening assay against 2'-phosphotransferase Tpt1p.
Nucleic acids symposium series (2004) 2008;(52):475-6.
2008: Alexander S Wahba; Masad J Damha; Robert H E Hudson
RNA containing pyrrolocytidine base analogs: good binding affinity and fluorescence that responds to hybridization.
Nucleic acids symposium series (2004) 2008;(52):399-400.
2008: Alexander S Wahba; Masad J Damha; Robert H E Hudson
RNA containing pyrrolocytidine base analogs: increased binding affinity and fluorescence that responds to hybridization.
Nucleic acids symposium series (2004) 2008;(52):397-8.
2008: Jeremy G Lackey; Masad J Damha
The acetal levulinyl ester (ALE) group for the 2'-hydroxyl protection of ribonucleosides and the synthesis of oligoribonucleotides.
Nucleic acids symposium series (2004) 2008;(52):35-6.
2007: Debbie Mitra; Masad J Damha
A novel approach to the synthesis of DNA and RNA lariats.
The Journal of organic chemistry 2007;72(25):9491-500.
2007: David Sabatino; Masad J Damha
Oxepane nucleic acids: synthesis, characterization, and properties of oligonucleotides bearing a seven-membered carbohydrate ring.
Journal of the American Chemical Society 2007;129(26):8259-70.
2007: Chang Geng Peng; Masad J Damha
Polymerase-directed synthesis of 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acids.
Journal of the American Chemical Society 2007;129(17):5310-1.
2007: Bénédicte M Pâtureau; Robert H E Hudson; Masad J Damha
Induction of RNase H activity by Arabinose-peptide nucleic acid chimeras.
Bioconjugate chemistry 2007;18(2):421-30.
2007: Jeremy G Lackey; David Sabatino; Masad J Damha
Solid-phase synthesis and on-column deprotection of RNA from 2'- (and 3'-) O-levulinated (Lv) ribonucleoside monomers.
Organic letters 2007;9(5):789-92.
2007: Robert A Donga; Matthew Hassler; Tak Hang Chan; Masad J Damha
Oligonucleotide synthesis using ionic liquids as soluble supports.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1287-93.
2007: Chang Geng Peng; Masad J Damha
DNA polymerase recognition of 2'-deoxy-2'-fluoroarabinonucleoside 5'-triphosphates (2'F-araNTPs).
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):1189-93.
2007: David Sabatino; Masad J Damha
Synthesis and properties of oligonucleotides containing a 7-membered (oxepane) sugar ring.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):1185-8.
2007: Chang Geng Peng; Masad J Damha
G-quadruplex induced stabilization by 2'-deoxy-2'-fluoro-D-arabinonucleic acids (2'F-ANA).
Nucleic acids research 2007;35(15):4977-88.
2007: Jonathan K Watts; Niloufar Choubdar; Kashinath Sadalapure; Francis Robert; Alexander S Wahba; Jerry Pelletier; B Mario Pinto; Masad J Damha
2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.
Nucleic acids research 2007;35(5):1441-51.
2006: Joanna B Opalinska; Anna Kalota; Jyoti Chattopadhyaya; Masad J Damha; Alan M Gewirtz
Nucleic acid therapeutics for hematologic malignancies--theoretical considerations.
Annals of the New York Academy of Sciences 2006;1082():124-36.
2006: Nicolay Ferrari; Denis Bergeron; Anna-Lisa Tedeschi; Maria M Mangos; Luc Paquet; Paolo M Renzi; Masad J Damha
Characterization of antisense oligonucleotides comprising 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (FANA): specificity, potency, and duration of activity.
Annals of the New York Academy of Sciences 2006;1082():91-102.
2006: Robert A Donga; Syed M Khaliq-Uz-Zaman; Tak Hang Chan; Masad J Damha
A novel approach to oligonucleotide synthesis using an imidazolium ion tag as a soluble support.
The Journal of organic chemistry 2006;71(20):7907-10.
2006: Jonathan K Watts; Kashinath Sadalapure; Niloufar Choubdar; B Mario Pinto; Masad J Damha
Synthesis and conformational analysis of 2'-fluoro-5-methyl-4'-thioarabinouridine (4'S-FMAU).
The Journal of organic chemistry 2006;71(3):921-5.
2006: Thomas Dowler; Denis Bergeron; Anna-Lisa Tedeschi; Luc Paquet; Nicolay Ferrari; Masad J Damha
Improvements in siRNA properties mediated by 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (FANA).
Nucleic acids research 2006;34(6):1669-75.
2006: Rawan Mourani; Masad J Damha
Synthesis, characterization, and biological properties of small branched RNA fragments containing chiral (Rp and Sp) 2',5'-phosphorothioate linkages.
Nucleosides, nucleotides & nucleic acids 2006;25(2):203-29.
2006: Anna Kalota; Lidia Karabon; Cezary R Swider; Ekaterina Viazovkina; Mohamed I Elzagheid; Masad J Damha; Alan M Gewirtz
2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing.
Nucleic acids research 2006;34(2):451-61.
2006: Daniel Gendron; Sandra Carriero; Daniel Garneau; Jonathan Villemaire; Roscoe Klinck; Sherif Abou Elela; Masad J Damha; Benoit Chabot
Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals.
BMC biotechnology 2006;6():5.
2005: Rami N Hannoush; Masad J Damha
Preference for ribose over deoxyribose in loop-closing base pairs of extra stable nucleic acid hairpins.
Nucleosides, nucleotides & nucleic acids 2005;24(10-12):1519-30.
2005: Chang Geng Peng; Masad J Damha
Synthesis and hybridization studies of oligonucleotides containing 1-(2-deoxy-2-alpha-C-hydroxymethyl-beta-D-ribofuranosyl)thymine (2'-alpha-hm-dT).
Nucleic acids research 2005;33(22):7019-28.
2005: M Fahad Khalid; Masad J Damha; Stewart Shuman; Beate Schwer
Structure-function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase.
Nucleic acids research 2005;33(19):6349-60.
2005: Annie Galarneau; Kyung-Lyum Min; Maria M Mangos; Masad J Damha
Assay for evaluating ribonuclease H-mediated degradation of RNA-antisense oligonucleotide duplexes.
Methods in molecular biology (Clifton, N.J.) 2005;288():65-80.
2004: Bruno Lamontagne; Rami N Hannoush; Masad J Damha; Sherif Abou Elela
Molecular requirements for duplex recognition and cleavage by eukaryotic RNase III: discovery of an RNA-dependent DNA cleavage activity of yeast Rnt1p.
Journal of molecular biology 2004;338(2):401-18.
2004: Rami N Hannoush; Sandra Carriero; Kyung-Lyum Min; Masad J Damha
Selective inhibition of HIV-1 reverse transcriptase (HIV-1 RT) RNase H by small RNA hairpins and dumbbells.
Chembiochem : a European journal of chemical biology 2004;5(4):527-33.
2004: Rami N Hannoush; Kyung-Lyum Min; Masad J Damha
Diversity-oriented solid-phase synthesis and biological evaluation of oligonucleotide hairpins as HIV-1 RT RNase H inhibitors.
Nucleic acids research 2004;32(21):6164-75.
2003: Sandra Carriero; Masad J Damha
Inhibition of pre-mRNA splicing by synthetic branched nucleic acids.
Nucleic acids research 2003;31(21):6157-67.
2003: Sandra Carriero; Masad J Damha
Template-mediated synthesis of lariat RNA and DNA.
The Journal of organic chemistry 2003;68(22):8328-38.
2003: Alexei Yu Denisov; Rami N Hannoush; Kalle Gehring; Masad J Damha
A novel RNA motif based on the structure of unusually stable 2',5'-linked r(UUCG) loops.
Journal of the American Chemical Society 2003;125(38):11525-31.
2003: Rami N Hannoush; Alexei Yu Denisov; Kalle Gehring; Masad J Damha
Structure of 2',5'-linked tetraribonucleotide loops: a novel RNA motif.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1687-90.
2003: Sandra Carriero; Maria M Mangos; Kazim A Agha; Anne M Noronha; Masad J Damha
Branchpoint sugar stereochemistry determines the hydrolytic susceptibility of branched RNA fragments by the yeast debranching enzyme (YDBR).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1599-602.
2003: Mohamed I Elzagheid; Anna Lisa Tedeschi; Masad J Damha
Synthesis of 2',3'-dideoxy-2'-fluoro-3'-thioarabinothymidine and its 3'-phosphoramidite derivative.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1343-6.
2003: Mohamed I Elzagheid; Ekaterina Viazovkina; Masad J Damha
A new synthesis of 9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine (AraF-G).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1339-42.
2003: Ekaterina Viazovkina; Kyung-Lyum Min; Annie Galarneau; Masad J Damha
Synthesis and properties of oligonucleotide chimeras containing 5'-amino-2'-deoxy-2'-fluoroarabinonucleosides.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1335-8.
2003: Ekaterina Viazovkina; Maria M Mangos; Masad J Damha
Synthesis and physicochemical properties of 2'-deoxy-2',2''-difluoro-beta-D-ribofuranosyl and 2'-deoxy-2',2''-difluoro-alpha-D-ribofuranosyl oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1251-4.
2003: Kazim A Agha; Masad J Damha
Synthesis and binding properties of a homopyrimidine 2',5'-linked xylose nucleic acid (2',5'-XNA).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1175-8.
2003: Sandra Carriero; Masad J Damha
Synthesis of lariat-DNA via the chemical ligation of a dumbbell complex.
Organic letters 2003;5(3):273-6.
2003: Maria M Mangos; Kyung-Lyum Min; Ekaterina Viazovkina; Annie Galarneau; Mohamed I Elzagheid; Michael A Parniak; Masad J Damha
Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2'F-ANA constructs containing acyclic nucleotide inserts.
Journal of the American Chemical Society 2003;125(3):654-61.
2002: Ekaterina Viazovkina; Maria M Mangos; Mohamed I Elzagheid; Masad J Damha
Solid-phase synthesis of 2'-deoxy-2'-fluoro- beta-D-oligoarabinonucleotides (2'F-ANA) and their phosphorothioate derivatives.
Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2002;Chapter 4():Unit 4.15.
2002: Mohamed I Elzagheid; Ekaterina Viazovkina; Masad J Damha
Synthesis of protected 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides.
Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2002;Chapter 1():Unit 1.7.
2002: Julie Lacombe; Ekaterina Viazovkina; Pascal N Bernatchez; Annie Galarneau; Masad J Damha; Martin G Sirois
Antisense inhibition of Flk-1 by oligonucleotides composed of 2'-deoxy-2'-fluoro-beta-D-arabino- and 2'-deoxy-nucleosides.
Canadian journal of physiology and pharmacology 2002;80(10):951-61.
2002: Maria M Mangos; Masad J Damha
Flexible and frozen sugar-modified nucleic acids--modulation of biological activity through furanose ring dynamics in the antisense strand.
Current topics in medicinal chemistry 2002;2(10):1147-71.
2002: Kyung-Lyum Min; Ekaterina Viazovkina; Annie Galarneau; Michael A Parniak; Masad J Damha
Oligonucleotides comprised of alternating 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides and D-2'-deoxyribonucleosides (2'F-ANA/DNA 'altimers') induce efficient RNA cleavage mediated by RNase H.
Bioorganic & medicinal chemistry letters 2002;12(18):2651-4.
2002: Sandra Carriero; Masad J Damha
Solid-phase synthesis of branched oligonucleotides.
Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2002;Chapter 4():Unit 4.14.
2002: Daniel R Yazbeck; Kyung-Lyum Min; Masad J Damha
Molecular requirements for degradation of a modified sense RNA strand by Escherichia coli ribonuclease H1.
Nucleic acids research 2002;30(14):3015-25.
2002: Chun-Nam Lok; Ekaterina Viazovkina; Kyung-Lyum Min; Eva Nagy; Christopher J Wilds; Masad J Damha; Michael A Parniak
Potent gene-specific inhibitory properties of mixed-backbone antisense oligonucleotides comprised of 2'-deoxy-2'-fluoro-D-arabinose and 2'-deoxyribose nucleotides.
Biochemistry 2002;41(10):3457-67.
2001: Rami N Hannoush; Masad J Damha
Remarkable stability of hairpins containing 2',5'-linked RNA loops.
Journal of the American Chemical Society 2001;123(49):12368-74.
2001: Alexei Yu Denisov; Anne M Noronha; Christopher J Wilds; Jean-Francois Trempe; RT Pon; Kalle Gehring; Masad J Damha
Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
Nucleic acids research 2001;29(21):4284-93.
2001: Jean-Francois Trempe; Christopher J Wilds; Alexei Yu Denisov; RT Pon; Masad J Damha; Kalle Gehring
NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes.
Journal of the American Chemical Society 2001;123(21):4896-903.
2001: Sandra Carriero; R S Braich; Robert H E Hudson; D Anglin; J D Friesen; Masad J Damha
Inhibition of in vitro pre-mRNA splicing in S. cerevisiae by branched oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):873-7.
2001: Masad J Damha; Anne M Noronha; Christopher J Wilds; Jean-Francois Trempe; Alexei Yu Denisov; RT Pon; Kalle Gehring
Properties of arabinonucleic acids (ANA & 20'F-ANA): implications for the design of antisense therapeutics that invoke RNase H cleavage of RNA.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):429-40.
2001: Anne M Noronha; Dominique Arion; Michael A Parniak; Masad J Damha
Effect of substituting arabinonucleosides for deoxynucleotides in the DNA priming strand on the polymerase action of HIV-1 RT.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):1205-9.
2001: Rami N Hannoush; Masad J Damha
Extra stable 2',5'-linked RNA loops.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):1201-4.
2000: Christopher J Wilds; Masad J Damha
2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides (2'F-ANA): synthesis and physicochemical studies.
Nucleic acids research 2000;28(18):3625-35.
2000: Anne M Noronha; Christopher J Wilds; Chun-Nam Lok; K Viazovkina; Dominique Arion; Michael A Parniak; Masad J Damha
Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA.RNA hybrid duplexes.
Biochemistry 2000;39(24):7050-62.
1999: Christopher J Wilds; Masad J Damha
Duplex recognition by oligonucleotides containing 2'-deoxy-2'-fluoro-D-arabinose and 2'-deoxy-2'-fluoro-D-ribose. Intermolecular 2'-OH-phosphate contacts versus sugar puckering in the stabilization of triple-helical complexes.
Bioconjugate chemistry 1999;10(2):299-305.
1998: Masad J Damha; Anne M Noronha
Recognition of nucleic acid double helices by homopyrimidine 2', 5'-linked RNA.
Nucleic acids research 1998;26(22):5152-6.
1998: Anne M Noronha; Masad J Damha
Triple helices containing arabinonucleotides in the third (Hoogsteen) strand: effects of inverted stereochemistry at the 2'-position of the sugar moiety.
Nucleic acids research 1998;26(11):2665-71.
1998: M Wasner; Dominique Arion; Gadi Borkow; Anne M Noronha; A H Uddin; Michael A Parniak; Masad J Damha
Physicochemical and biochemical properties of 2',5'-linked RNA and 2',5'-RNA:3',5'-RNA "hybrid" duplexes.
Biochemistry 1998;37(20):7478-86.
1997: S Robidoux; Masad J Damha
D-2-deoxyribose and D-arabinose, but not D-ribose, stabilize the cytosine tetrad (i-DNA) structure.
Journal of biomolecular structure & dynamics 1997;15(3):529-35.
1997: S Robidoux; Roscoe Klinck; Kalle Gehring; Masad J Damha
Association of branched oligonucleotides into the i-motif.
Journal of biomolecular structure & dynamics 1997;15(3):517-27.
1997: Gadi Borkow; Dominique Arion; Anne M Noronha; M Scartozzi; Masad J Damha; Michael A Parniak
Inhibitory potency of R-region specific antisense oligonucleotides against in vitro DNA polymerization and template-switching reactions catalysed by HIV-1 reverse transcriptase.
The international journal of biochemistry & cell biology 1997;29(11):1285-95.
1997: A H Uddin; Paul A E Piunno; Robert H E Hudson; Masad J Damha; Ulrich J Krull
A fiber optic biosensor for fluorimetric detection of triple-helical DNA.
Nucleic acids research 1997;25(20):4139-46.
1997: R S Braich; Masad J Damha
Regiospecific solid-phase synthesis of branched oligonucleotides. Effect of vicinal 2',5'- (or 2',3'-) and 3',5'-phosphodiester linkages on the formation of hairpin DNA.
Bioconjugate chemistry 1997;8(3):370-7.
1996: Peter M Macdonald; Masad J Damha; K Ganeshan; R Braich; S V Zabarylo
Phosphorus 31 solid state NMR characterization of oligonucleotides covalently bound to a solid support.
Nucleic acids research 1996;24(15):2868-76.
1995: Masad J Damha; B Meng; D Wang; C G Yannopoulos; G Just
Structural basis for the RNA binding selectivity of oligonucleotide analogues containing alkylsulfide internucleoside linkages and 2'-substituted 3'-deoxyribonucleosides.
Nucleic acids research 1995;23(19):3967-73.
1995: P A Piunno; U J Krull; R H Hudson; Masad J Damha; H Cohen
Fiber-optic DNA sensor for fluorometric nucleic acid determination.
Analytical chemistry 1995;67(15):2635-43.
1994: K Nam; R H Hudson; K B Chapman; K Ganeshan; Masad J Damha; Jef Boeke
Yeast lariat debranching enzyme. Substrate and sequence specificity.
The Journal of biological chemistry 1994;269(32):20613-21.
1994: Masad J Damha; P A Giannaris; P Marfey
Antisense L/D-oligodeoxynucleotide chimeras: nuclease stability, base-pairing properties, and activity at directing ribonuclease H.
Biochemistry 1994;33(25):7877-85.
1993: P A Giannaris; Masad J Damha
Oligoribonucleotides containing 2',5'-phosphodiester linkages exhibit binding selectivity for 3',5'-RNA over 3',5'-ssDNA.
Nucleic acids research 1993;21(20):4742-9.
1993: S H Kawai; D Wang; P A Giannaris; Masad J Damha; G Just
Solid-phase synthesis and hybridization properties of DNA containing sulfide-linked dinucleosides.
Nucleic acids research 1993;21(6):1473-9.
1993: R H Hudson; Masad J Damha
Association of branched nucleic acids.
Nucleic acids symposium series 1993;(29):97-9.
1993: Masad J Damha; K K Ogilvie
Oligoribonucleotide synthesis. The silyl-phosphoramidite method.
Methods in molecular biology (Clifton, N.J.) 1993;20():81-114.
1992: Masad J Damha; K Ganeshan; R H Hudson; S V Zabarylo
Solid-phase synthesis of branched oligoribonucleotides related to messenger RNA splicing intermediates.
Nucleic acids research 1992;20(24):6565-73.
1991: Masad J Damha; R H Hudson; K Ganeshan; S V Zabarylo; Y Guo
Synthesis and properties of branched and hyperbranched oligonucleotides.
Nucleic acids symposium series 1991;(24):203-4.
1991: Masad J Damha; P A Giannaris; N Khan
2'-5'-linked oligonucleotides form stable complexes with complementary RNA and DNA.
Nucleic acids symposium series 1991;(24):290.
1990: Masad J Damha; P A Giannaris; S V Zabarylo
An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis.
Nucleic acids research 1990;18(13):3813-21.
1988: Masad J Damha; K K Ogilvie
Conformational properties of branched RNA fragments in aqueous solution.
Biochemistry 1988;27(17):6403-16.
1986: Richard T Pon; N Usman; Masad J Damha; K K Ogilvie
Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives.
Nucleic acids research 1986;14(16):6453-70.
1985: Richard T Pon; Masad J Damha; K K Ogilvie
Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides.
Nucleic acids research 1985;13(18):6447-65.