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Patricia D'Amore

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Procedures

Coculture Techniques

Disorders

Neovascularization, Pathologic

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Publications

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Wen Allen Tseng; Kameran Lashkari; Thuzar Thein; Patricia A D'Amore; Meredith S Gregory; Kati Kinnunen; Bruce R Ksander
NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration.
Knatokie M Ford; magali Saint-Geniez; Tony E Walshe; Patricia A D'Amore
Expression and role of VEGF--a in the ciliary body.
Leo A Kim; Patricia A D'Amore
A brief history of anti-VEGF for the treatment of ocular angiogenesis.

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All Publications

2013: Wen Allen Tseng; Kameran Lashkari; Thuzar Thein; Patricia A D'Amore; Meredith S Gregory; Kati Kinnunen; Bruce R Ksander
NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration.
Investigative ophthalmology & visual science 2013;54(1):110-20.
2012: Knatokie M Ford; magali Saint-Geniez; Tony E Walshe; Patricia A D'Amore
Expression and role of VEGF--a in the ciliary body.
Investigative ophthalmology & visual science 2012;53(12):7520-7.
2012: Leo A Kim; Patricia A D'Amore
A brief history of anti-VEGF for the treatment of ocular angiogenesis.
The American journal of pathology 2012;181(2):376-9.
2012: Nathaniel G dela Paz; Lyndsay L Leach; magali Saint-Geniez; Tony E Walshe; Patricia A D'Amore
Role of shear-stress-induced VEGF expression in endothelial cell survival.
Journal of cell science 2012;125(Pt 4):831-43.
2012: Eiichi Sekiyama; Tony E Walshe; Kazuhito Yoneda; Ali Hafezi-Moghadam; Toshio Hisatomi; Shigeru Kinoshita; Kazuichi Maruyama; Joan W Miller; Shintaro Nakao; magali Saint-Geniez; Patricia A D'Amore
Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(2):567-75.
2011: Diane C Darland; Tristan Darland; Sarah Frisch; Patrick W Odens; magali Saint-Geniez; Geoffrey J Schaubhut; Anat Stemmer-Rachamimov; Matthew A Berosik; Jacob T Cain; Patricia A D'Amore
Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development.
Developmental biology 2011;358(1):9-22.
2010: Brad A Bryan; Emily Dennstedt; Dianne C Mitchell; Tony E Walshe; Kensuke Noma; Robyn Loureiro; magali Saint-Geniez; Jean-Paul Campaigniac; James K Liao; Patricia A D'Amore
RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(9):3186-95.
2009: magali Saint-Geniez; Tomoki Kurihara; Eiichi Sekiyama; Angel E Maldonado; Patricia A D'Amore
An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18751-6.
2009: Tony E Walshe; Vandana S Dole; Arindel S R Maharaj; Ian S Patten; Denisa D Wagner; Patricia A D'Amore
Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(8):1185-92.
2009: Tony E Walshe; magali Saint-Geniez; Arindel S R Maharaj; Eiichi Sekiyama; Angel E Maldonado; Patricia A D'Amore
TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature.
PloS one 2009;4(4):e5149.
2009: Nathaniel G dela Paz; Patricia A D'Amore
Arterial versus venous endothelial cells.
Cell and tissue research 2009;335(1):5-16.
2009: magali Saint-Geniez; Tomoki Kurihara; Patricia A D'Amore
Role of cell and matrix-bound VEGF isoforms in lens development.
Investigative ophthalmology & visual science 2009;50(1):311-21.
2008: Wendy Chao; Patricia A D'Amore
IGF2: epigenetic regulation and role in development and disease.
Cytokine & growth factor reviews 2008;19(2):111-20.
2008: Brad A Bryan; Tony E Walshe; Dianne C Mitchell; Joshua Havumaki; magali Saint-Geniez; Arindel S Maharaj; Angel E Maldonado; Patricia A D'Amore
Coordinated vascular endothelial growth factor expression and signaling during skeletal myogenic differentiation.
Molecular biology of the cell 2008;19(3):994-1006.
2008: Arindel S R Maharaj; Tony E Walshe; magali Saint-Geniez; Shivalingappa Venkatesha; Angel E Maldonado; Nathan C Himes; Kabir S Matharu; S Ananth Karumanchi; Patricia A D'Amore
VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma.
The Journal of experimental medicine 2008;205(2):491-501.
2008: magali Saint-Geniez; Arindel S R Maharaj; Tony E Walshe; Budd A Tucker; Eiichi Sekiyama; Tomoki Kurihara; Diane C Darland; Michael J Young; Patricia A D'Amore
Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors.
PloS one 2008;3(11):e3554.
2008: Tony E Walshe; Patricia A D'Amore
The role of hypoxia in vascular injury and repair.
Annual review of pathology 2008;3():615-43.
2007: Jay Harper; Li Yan; Robyn M Loureiro; Iinmin Wu; Jianmin Fang; Patricia A D'Amore; Marsha A Moses
Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24.
Cancer research 2007;67(18):8736-41.
2007: Arindel S R Maharaj; Patricia A D'Amore
Roles for VEGF in the adult.
Microvascular research 2007;74(2-3):100-13.
2007: Markus Ramsauer; Patricia A D'Amore
Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization.
Journal of cell science 2007;120(Pt 10):1810-7.
2007: Kazuichi Maruyama; Jun Asai; Masaaki Ii; Tina Thorne; Douglas Losordo; Patricia A D'Amore
Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.
The American journal of pathology 2007;170(4):1178-91.
2007: Anne M Goodwin; Jan Kitajewski; Patricia A D'Amore
Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not.
Growth factors (Chur, Switzerland) 2007;25(1):25-32.
2006: Anne M Goodwin; Kaitlyn M Sullivan; Patricia A D'Amore
Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(11):3110-20.
2006: magali Saint-Geniez; Angel E Maldonado; Patricia A D'Amore
VEGF expression and receptor activation in the choroid during development and in the adult.
Investigative ophthalmology & visual science 2006;47(7):3135-42.
2006: Arindel S R Maharaj; magali Saint-Geniez; Angel E Maldonado; Patricia A D'Amore
Vascular endothelial growth factor localization in the adult.
The American journal of pathology 2006;168(2):639-48.
2005: Kazuichi Maruyama; Masaaki Ii; Claus Cursiefen; David G Jackson; Hiroshi Keino; Minoru Tomita; Nico van Rooijen; Hideya Takenaka; Patricia A D'Amore; Joan Stein-Streilein; Douglas Losordo; J Wayne Streilein
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages.
The Journal of clinical investigation 2005;115(9):2363-72.
2005: Shulamit Levenberg; Jeroen Rouwkema; Mara Macdonald; Evan Garfein; Daniel S Kohane; Diane C Darland; Robert Marini; Clemens A van Blitterswijk; Richard C Mulligan; Patricia A D'Amore; Robert Langer
Engineering vascularized skeletal muscle tissue.
Nature biotechnology 2005;23(7):879-84.
2005: Joseph F Arboleda-Velasquez; Raajit Rampal; Erik Fung; Diane C Darland; Min Liu; Maria C Martinez; Christine P Donahue; Manuel F Navarro-Gonzalez; Peter Libby; Patricia A D'Amore; Masanori Aikawa; Robert S Haltiwanger; Kenneth S Kosik
CADASIL mutations impair Notch3 glycosylation by Fringe.
Human molecular genetics 2005;14(12):1631-9.
2005: Robyn Loureiro; Patricia A D'Amore
Transcriptional regulation of vascular endothelial growth factor in cancer.
Cytokine & growth factor reviews 2005;16(1):77-89.
2005: Robyn Loureiro; Arindel S R Maharaj; David Dankort; William J Muller; Patricia A D'Amore
ErbB2 overexpression in mammary cells upregulates VEGF through the core promoter.
Biochemical and biophysical research communications 2005;326(2):455-65.
2005: Paul N Morris; Benjamin J Dunmore; Amir Tadros; Douglas A Marchuk; Diane C Darland; Patricia A D'Amore; Nicholas P J Brindle
Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations.
Journal of molecular medicine (Berlin, Germany) 2005;83(1):58-63.
2004: Rubai Ding; Diane C Darland; Michael S Parmacek; Patricia A D'Amore
Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation.
Stem cells and development 2004;13(5):509-20.
2004: Yin-Shan Ng; Markus Ramsauer; Robyn Loureiro; Patricia A D'Amore
Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies.
Laboratory investigation; a journal of technical methods and pathology 2004;84(9):1209-18.
2004: Claudia M Garcia; Diane C Darland; Lauren J Massingham; Patricia A D'Amore
Endothelial cell-astrocyte interactions and TGF beta are required for induction of blood-neural barrier properties.
Brain research. Developmental brain research 2004;152(1):25-38.
2004: Robert Chang; Steven Andreoli; Yin-Shan Ng; Thanh Truong; Sandra R Smith; Jay Wilson; Patricia A D'Amore
VEGF expression is downregulated in nitrofen-induced congenital diaphragmatic hernia.
Journal of pediatric surgery 2004;39(6):825-8; discussion 825-8.
2004: Laurence H Beck; Anne M Goodwin; Patricia A D'Amore
Culture of large vessel endothelial cells on floating collagen gels promotes a phenotype characteristic of endothelium in vivo.
Differentiation; research in biological diversity 2004;72(4):162-70.
2004: Claus Cursiefen; Lu Chen; Leonardo P Borges; David Jackson; Jingtai Cao; Czeslaw Radziejewski; Patricia A D'Amore; M Reza Dana; Stanley J Wiegand; J Wayne Streilein
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment.
The Journal of clinical investigation 2004;113(7):1040-50.
2004: magali Saint-Geniez; Patricia A D'Amore
Development and pathology of the hyaloid, choroidal and retinal vasculature.
The International journal of developmental biology 2004;48(8-9):1045-58.
2003: Diane C Darland; L J Massingham; S R Smith; E Piek; magali Saint-Geniez; Patricia A D'Amore
Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival.
Developmental biology 2003;264(1):275-88.
2003: M Elizabeth Hartnett; Alexandra Lappas; Diane C Darland; Janet R McColm; Stephanie Lovejoy; Patricia A D'Amore
Retinal pigment epithelium and endothelial cell interaction causes retinal pigment epithelial barrier dysfunction via a soluble VEGF-dependent mechanism.
Experimental eye research 2003;77(5):593-9.
2003: Susumu Ishida; Tomohiko Usui; Kenji Yamashiro; Yuichi Kaji; Shiro Amano; Yuichiro Ogura; Tetsuo Hida; Yoshihisa Oguchi; Jayakrishna Ambati; Joan W Miller; Evangelos S Gragoudas; Yin-Shan Ng; Patricia A D'Amore; David T Shima; Anthony P Adamis
VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization.
The Journal of experimental medicine 2003;198(3):483-9.
2002: Markus Ramsauer; Patricia A D'Amore
Getting Tie(2)d up in angiogenesis.
The Journal of clinical investigation 2002;110(11):1615-7.
2002: Patricia A D'Amore; Yin-Shan Ng
Won't you be my neighbor? Local induction of arteriogenesis.
Cell 2002;110(3):289-92.
2002: Csaba Galambos; Yin-Shan Ng; Ayoob Ali; Akihiko Noguchi; Stephanie Lovejoy; Patricia A D'Amore; Daphne E Demello
Defective pulmonary development in the absence of heparin-binding vascular endothelial growth factor isoforms.
American journal of respiratory cell and molecular biology 2002;27(2):194-203.
2002: Patricia A D'Amore; Yin-Shan Ng
Tales of the cryptic: unveiling more angiogenesis inhibitors.
Trends in molecular medicine 2002;8(7):313-5.
2002: Elazar Zelzer; William McLean; Yin-Shan Ng; Naomi Fukai; Anthony M Reginato; Stephanie Lovejoy; Patricia A D'Amore; Bjorn R Olsen
Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis.
Development (Cambridge, England) 2002;129(8):1893-904.
2002: Ingeborg Stalmans; Yin-Shan Ng; Richard M Rohan; Marcus Fruttiger; Ann Bouché; Ali Yuce; Hajime Fujisawa; Bart Hermans; Moshe Shani; Sandra Jansen; Daniel J Hicklin; David J Anderson; Tom Gardiner; Hans-Peter Hammes; Lieve Moons; Mieke Dewerchin; Désiré Collen; Peter Carmeliet; Patricia A D'Amore
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms.
The Journal of clinical investigation 2002;109(3):327-36.
2002: Anne M Goodwin; Patricia A D'Amore
Wnt signaling in the vasculature.
Angiogenesis 2002;5(1-2):1-9.
2001: Yin-Shan Ng; Richard M Rohan; Mary E Sunday; Daphne E Demello; Patricia A D'Amore
Differential expression of VEGF isoforms in mouse during development and in the adult.
Developmental dynamics : an official publication of the American Association of Anatomists 2001;220(2):112-21.
2001: Diane C Darland; Patricia A D'Amore
TGF beta is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells.
Angiogenesis 2001;4(1):11-20.
2001: Diane C Darland; Patricia A D'Amore
Cell-cell interactions in vascular development.
Current topics in developmental biology 2001;52():107-49.
1999: M Elizabeth Hartnett; C M Garcia; Patricia A D'Amore
Release of bFGF, an endothelial cell survival factor, by osmotic shock.
Investigative ophthalmology & visual science 1999;40(12):2945-51.
1999: Peter Carmeliet; Yin-Shan Ng; Dieter Nuyens; Gregor Theilmeier; Koen Brusselmans; I Cornelissen; E Ehler; V V Kakkar; Ingeborg Stalmans; Virginie Mattot; J C Perriard; Mieke Dewerchin; Willem Flameng; Andras Nagy; Florea Lupu; Lieve Moons; Désiré Collen; Patricia A D'Amore; David T Shima
Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.
Nature medicine 1999;5(5):495-502.
1999: K K Hirschi; SA Rohovsky; L H Beck; S R Smith; Patricia A D'Amore
Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact.
Circulation research 1999;84(3):298-305.
1999: Diane C Darland; Patricia A D'Amore
Blood vessel maturation: vascular development comes of age.
The Journal of clinical investigation 1999;103(2):157-8.
1997: K K Hirschi; SA Rohovsky; Patricia A D'Amore
Cell-cell interactions in vessel assembly: a model for the fundamentals of vascular remodelling.
Transplant immunology 1997;5(3):177-8.
1997: K K Hirschi; Patricia A D'Amore
Control of angiogenesis by the pericyte: molecular mechanisms and significance.
EXS 1997;79():419-28.
1996: S Rohovsky; M Kearney; Anne Pieczek; Kenneth Rosenfield; Robert M Schainfeld; Patricia A D'Amore; Jeffrey M Isner
Elevated levels of basic fibroblast growth factor in patients with limb ischemia.
American heart journal 1996;132(5):1015-9.