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Caroline Damsky
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Research Profile (preview)
Chemicals & Drugs
Anatomy
Physiology
Living Beings
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Network (preview)
13
Fisher, Susan
12
Ilic, Dusko
9
Werb, Zena
6
Zhou, Yan
5
Schlaepfer, David
4
Janatpour, Mary
4
Genbacev, Olga
4
Almeida, EA
3
Gardner, David
3
Globus, RK
3
Jin, Fang
3
Kovacic, Branka
3
Logan, Susan
3
McMaster, Michael
3
Dazin, Paul
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All Publications
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2008: Johnson Lynn; Genco Robert J; Damsky Caroline; Haden N Karl; Hart Suzanne; Hart Thomas C; Shuler Charles F; Tabak Lawrence A; tedesco Lisa A
Genetics and its implications for clinical dental practice and education: report of panel 3 of the Macy study.
Journal of dental education 2008;72(2 Suppl):86-94.
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2007: Kim Jae-Beom; Leucht Philipp; Luppen Cynthia A; Park Yu Jin; Beggs Hilary E; Damsky Caroline H; Helms Jill A
Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration.
Bone 2007;41(1):39-51.
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2004: Damsky Caroline
Interview with Caroline Damsky.
Journal of cell science 2004;117(Pt 17):3713-4.
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2004: Ilic Dusko; Kovacic Branka; Johkura Kohei; Schlaepfer David D; Tomasevic Nenad; Han Qin; Kim Jae-Beom; Howerton Kyle; Baumbusch Clark; Ogiwara Naoko; Streblow Daniel N; Nelson Jay A; Dazin Paul; Shino Yuji; Sasaki Katsunori; Damsky Caroline H
FAK promotes organization of fibronectin matrix and fibrillar adhesions.
Journal of cell science 2004;117(Pt 2):177-87.
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2003: Ilic Dusko; Kovacic Branka; McDonagh Susan; Jin Fang; Baumbusch Clark; Gardner David G; Damsky Caroline H
Focal adhesion kinase is required for blood vessel morphogenesis.
Circulation research 2003;92(3):300-7.
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2002: Kamiya Nobuhiro; Jikko Akitoshi; Kimata Koji; Damsky Caroline; Shimizu Katsuji; Watanabe Hideto
Establishment of a novel chondrocytic cell line N1511 derived from p53-null mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(10):1832-42.
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2002: Damsky Caroline H; Ilic Dusko
Integrin signaling: it's where the action is.
Current opinion in cell biology 2002;14(5):594-602.
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2002: Damsky Caroline; Heidaran Mohammad; Bottaro Donald; Crossin Kathryn; Ducy Patricia; Ingber Donald
Molecular signaling: breakout session summary.
Annals of the New York Academy of Sciences 2002;961():164-7.
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2002: Damsky Caroline
Cell-cell and cell-extracellular matrix adhesion receptors.
Annals of the New York Academy of Sciences 2002;961():154-5.
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2002: Zhou Yan; McMaster Michael; Woo Kirstin; Janatpour Mary; Perry Jean; Karpanen Terhi; Alitalo Kari; Damsky Caroline; Fisher Susan J
Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome.
The American journal of pathology 2002;160(4):1405-23.
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2001: Kovacic-Milivojevic B; Roediger F; Almeida E A; Damsky C H; Gardner D G; Ilic D
Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy.
Molecular biology of the cell 2001;12(8):2290-307.
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2001: Ilic D; Genbacev O; Jin F; Caceres E; Almeida E A; Bellingard-Dubouchaud V; Schaefer E M; Damsky C H; Fisher S J
Plasma membrane-associated pY397FAK is a marker of cytotrophoblast invasion in vivo and in vitro.
The American journal of pathology 2001;159(1):93-108.
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2000: Sieg D J; Hauck C R; Ilic D; Klingbeil C K; Schaefer E; Damsky C H; Schlaepfer D D
FAK integrates growth-factor and integrin signals to promote cell migration.
Nature cell biology 2000;2(5):249-56.
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2000: Almeida E A; Ilic D; Han Q; Hauck C R; Jin F; Kawakatsu H; Schlaepfer D D; Damsky C H
Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase.
The Journal of cell biology 2000;149(3):741-54.
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2000: Zimmerman D; Jin F; Leboy P; Hardy S; Damsky C
Impaired bone formation in transgenic mice resulting from altered integrin function in osteoblasts.
Developmental biology 2000;220(1):2-15.
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1999: Suen P W; Ilic D; Caveggion E; Berton G; Damsky C H; Lowell C A
Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages.
Journal of cell science 1999;112 ( Pt 22)():4067-78.
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1999: Jikko A; Harris S E; Chen D; Mendrick D L; Damsky C H
Collagen integrin receptors regulate early osteoblast differentiation induced by BMP-2.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(7):1075-83.
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1998: Kovacic B; Ilic D; Damsky C H; Gardner D G
c-Src activation plays a role in endothelin-dependent hypertrophy of the cardiac myocyte.
The Journal of biological chemistry 1998;273(52):35185-93.
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1998: Damsky C H; Fisher S J
Trophoblast pseudo-vasculogenesis: faking it with endothelial adhesion receptors.
Current opinion in cell biology 1998;10(5):660-6.
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1998: Ilic D; Almeida E A; Schlaepfer D D; Dazin P; Aizawa S; Damsky C H
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.
The Journal of cell biology 1998;143(2):547-60.
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1998: Sieg D J; Ilic D; Jones K C; Damsky C H; Hunter T; Schlaepfer D D
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.
The EMBO journal 1998;17(20):5933-47.
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1998: Zhou Y; Genbacev O; Damsky C H; Fisher S J
Oxygen regulates human cytotrophoblast differentiation and invasion: implications for endovascular invasion in normal pregnancy and in pre-eclampsia.
Journal of reproductive immunology 1998;39(1-2):197-213.
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1998: Globus R K; Doty S B; Lull J C; Holmuhamedov E; Humphries M J; Damsky C H
Fibronectin is a survival factor for differentiated osteoblasts.
Journal of cell science 1998;111 ( Pt 10)():1385-93.
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1997: Moursi A M; Globus R K; Damsky C H
Interactions between integrin receptors and fibronectin are required for calvarial osteoblast differentiation in vitro.
Journal of cell science 1997;110 ( Pt 18)():2187-96.
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1997: Zhou Y; Damsky C H; Fisher S J
Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?
The Journal of clinical investigation 1997;99(9):2152-64.
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1997: Zhou Y; Fisher S J; Janatpour M; Genbacev O; Dejana E; Wheelock M; Damsky C H
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
The Journal of clinical investigation 1997;99(9):2139-51.
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1997: Damsky C H; Moursi A; Zhou Y; Fisher S J; Globus R K
The solid state environment orchestrates embryonic development and tissue remodeling.
Kidney international 1997;51(5):1427-33.
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1997: Ilic D; Damsky C H; Yamamoto T
Focal adhesion kinase: at the crossroads of signal transduction.
Journal of cell science 1997;110 ( Pt 4)():401-7.
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1996: Huttenlocher A; Werb Z; Tremble P; Huhtala P; Rosenberg L; Damsky C H
Decorin regulates collagenase gene expression in fibroblasts adhering to vitronectin.
Matrix biology : journal of the International Society for Matrix Biology 1996;15(4):239-50.
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1996: Logan S K; Hansell E J; Damsky C H; Werb Z
T-antigen inhibits metalloproteinase expression and invasion in human placental cells transformed with temperature-sensitive simian virus 40.
Matrix biology : journal of the International Society for Matrix Biology 1996;15(2):81-9.
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1996: Moursi A M; Damsky C H; Lull J; Zimmerman D; Doty S B; Aota S; Globus R K
Fibronectin regulates calvarial osteoblast differentiation.
Journal of cell science 1996;109 ( Pt 6)():1369-80.
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1996: Xia M; Sreedharan S P; Dazin P; Damsky C H; Goetzl E J
Integrin-dependent role of human T cell matrix metalloproteinase activity in chemotaxis through a model basement membrane.
Journal of cellular biochemistry 1996;61(3):452-8.
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1996: Genbacev O; Joslin R; Damsky C H; Polliotti B M; Fisher S J
Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia.
The Journal of clinical investigation 1996;97(2):540-50.
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1995: Globus R K; Moursi A; Zimmerman D; Lull J; Damsky C
Integrin-extracellular matrix interactions in connective tissue remodeling and osteoblast differentiation.
ASGSB bulletin : publication of the American Society for Gravitational and Space Biology 1995;8(2):19-28.
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1995: Stephens L E; Sutherland A E; Klimanskaya I V; Andrieux A; Meneses J; Pedersen R A; Damsky C H
Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.
Genes & development 1995;9(15):1883-95.
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1995: Filardo E J; Brooks P C; Deming S L; Damsky C; Cheresh D A
Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.
The Journal of cell biology 1995;130(2):441-50.
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1995: Tremble P; Damsky C H; Werb Z
Components of the nuclear signaling cascade that regulate collagenase gene expression in response to integrin-derived signals.
The Journal of cell biology 1995;129(6):1707-20.
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1995: Huhtala P; Humphries M J; McCarthy J B; Tremble P M; Werb Z; Damsky C H
Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin.
The Journal of cell biology 1995;129(3):867-79.
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1995: McMaster M T; Librach C L; Zhou Y; Lim K H; Janatpour M J; DeMars R; Kovats S; Damsky C; Fisher S J
Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3771-8.
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1994: Damsky C H; Librach C; Lim K H; Fitzgerald M L; McMaster M T; Janatpour M; Zhou Y; Logan S K; Fisher S J
Integrin switching regulates normal trophoblast invasion.
Development (Cambridge, England) 1994;120(12):3657-66.
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1994: Moss L; Prakobphol A; Wiedmann T W; Fisher S J; Damsky C H
Glycosylation of human trophoblast integrins is stage and cell-type specific.
Glycobiology 1994;4(5):567-75.
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1993: Sutherland A E; Calarco P G; Damsky C H
Developmental regulation of integrin expression at the time of implantation in the mouse embryo.
Development (Cambridge, England) 1993;119(4):1175-86.
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1993: Stephens L E; Sonne J E; Fitzgerald M L; Damsky C H
Targeted deletion of beta 1 integrins in F9 embryonal carcinoma cells affects morphological differentiation but not tissue-specific gene expression.
The Journal of cell biology 1993;123(6 Pt 1):1607-20.
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1993: Damsky C; Sutherland A; Fisher S
Extracellular matrix 5: adhesive interactions in early mammalian embryogenesis, implantation, and placentation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(14):1320-9.
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1993: Tomaselli K J; Doherty P; Emmett C J; Damsky C H; Walsh F S; Reichardt L F
Expression of beta 1 integrins in sensory neurons of the dorsal root ganglion and their functions in neurite outgrowth on two laminin isoforms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(11):4880-8.
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1993: Burdsal C A; Damsky C H; Pedersen R A
The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak.
Development (Cambridge, England) 1993;118(3):829-44.
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1993: Zhou Y; Damsky C H; Chiu K; Roberts J M; Fisher S J
Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts.
The Journal of clinical investigation 1993;91(3):950-60.
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1992: Logan S K; Fisher S J; Damsky C H
Human placental cells transformed with temperature-sensitive simian virus 40 are immortalized and mimic the phenotype of invasive cytotrophoblasts at both permissive and nonpermissive temperatures.
Cancer research 1992;52(21):6001-9.
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1992: Arrick B A; Lopez A R; Elfman F; Ebner R; Damsky C H; Derynck R
Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1.
The Journal of cell biology 1992;118(3):715-26.
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1992: Demeure M J; Damsky C H; Elfman F; Goretzki P E; Wong M G; Clark O H
Invasion by cultured human follicular thyroid cancer correlates with increased beta 1 integrins and production of proteases.
World journal of surgery 1992;16(4):770-6.
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1992: Tournier J M; Goldstein G A; Hall D E; Damsky C H; Basbaum C B
Extracellular matrix proteins regulate morphologic and biochemical properties of tracheal gland serous cells through integrins.
American journal of respiratory cell and molecular biology 1992;6(5):461-71.
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1992: Damsky C H; Fitzgerald M L; Fisher S J
Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo.
The Journal of clinical investigation 1992;89(1):210-22.
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1992: Tremble P M; Damsky C H; Werb Z
Fibronectin fragments, but not intact fibronectin, signalling through the fibronectin receptor induce metalloproteinase gene expression in fibroblasts.
Matrix (Stuttgart, Germany). Supplement 1992;1():212-4.
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1992: Damsky C; Tremble P; Werb Z
Signal transduction via the fibronectin receptor: do integrins regulate matrix remodeling?
Matrix (Stuttgart, Germany). Supplement 1992;1():184-91.
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1991: Sutherland A E; Sanderson R D; Mayes M; Seibert M; Calarco P G; Bernfield M; Damsky C H
Expression of syndecan, a putative low affinity fibroblast growth factor receptor, in the early mouse embryo.
Development (Cambridge, England) 1991;113(1):339-51.
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1991: Librach C L; Werb Z; Fitzgerald M L; Chiu K; Corwin N M; Esteves R A; Grobelny D; Galardy R; Damsky C H; Fisher S J
92-kD type IV collagenase mediates invasion of human cytotrophoblasts.
The Journal of cell biology 1991;113(2):437-49.
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1990: Werb Z; Tremble P; Damsky C H
Regulation of extracellular matrix degradation by cell-extracellular matrix interactions.
Cell differentiation and development : the official journal of the International Society of Developmental Biologists 1990;32(3):299-306.
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1990: Hall D E; Reichardt L F; Crowley E; Holley B; Moezzi H; Sonnenberg A; Damsky C H
The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.
The Journal of cell biology 1990;110(6):2175-84.
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1989: Werb Z; Tremble P M; Behrendtsen O; Crowley E; Damsky C H
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.
The Journal of cell biology 1989;109(2):877-89.
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1989: Fisher S J; Cui T Y; Zhang L; Hartman L; Grahl K; Zhang G Y; Tarpey J; Damsky C H
Adhesive and degradative properties of human placental cytotrophoblast cells in vitro.
The Journal of cell biology 1989;109(2):891-902.
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1989: Brown D L; Phillips D R; Damsky C H; Charo I F
Synthesis and expression of the fibroblast fibronectin receptor in human monocytes.
The Journal of clinical investigation 1989;84(1):366-70.
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1989: Kramer R H; McDonald K A; Crowley E; Ramos D M; Damsky C H
Melanoma cell adhesion to basement membrane mediated by integrin-related complexes.
Cancer research 1989;49(2):393-402.
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1988: Tomaselli K J; Damsky C H; Reichardt L F
Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen.
The Journal of cell biology 1988;107(3):1241-52.
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1988: Sutherland A E; Calarco P G; Damsky C H
Expression and function of cell surface extracellular matrix receptors in mouse blastocyst attachment and outgrowth.
The Journal of cell biology 1988;106(4):1331-48.
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1987: Tomaselli K J; Damsky C H; Reichardt L F
Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth.
The Journal of cell biology 1987;105(5):2347-58.
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