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Hannelore Daniel

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Antonia Rizzello; Alessandro Romano; Carlo Storelli; Tiziano Verri; Raffaele Acierno; Hannelore Daniel; Gabor Kottra; Michele Maffia
Protein cold adaptation strategy via a unique seven-amino acid domain in the icefish (Chionodraco hamatus) PEPT1 transporter.
Charles Desmarchelier; Martin Klingenspor; Tobias Ludwig; Nadine Rink; Ronny Scheundel; Bernhard L Bader; Hannelore Daniel
Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition.
Christoph Dahlhoff; Bernhard L Bader; Charles Desmarchelier; Rainer W Fürst; Jürgen Geisel; Alexander Haag; Björn Hummel; Rima Obeid; Manuela Sailer; Susanne E Ulbrich; Hannelore Daniel
Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.

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All Publications

2013: Antonia Rizzello; Alessandro Romano; Carlo Storelli; Tiziano Verri; Raffaele Acierno; Hannelore Daniel; Gabor Kottra; Michele Maffia
Protein cold adaptation strategy via a unique seven-amino acid domain in the icefish (Chionodraco hamatus) PEPT1 transporter.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(17):7068-73.
2013: Charles Desmarchelier; Martin Klingenspor; Tobias Ludwig; Nadine Rink; Ronny Scheundel; Bernhard L Bader; Hannelore Daniel
Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition.
The British journal of nutrition 2013;109(8):1518-27.
2013: Christoph Dahlhoff; Bernhard L Bader; Charles Desmarchelier; Rainer W Fürst; Jürgen Geisel; Alexander Haag; Björn Hummel; Rima Obeid; Manuela Sailer; Susanne E Ulbrich; Hannelore Daniel
Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.
PloS one 2013;8(3):e57387.
2012: Kerstin E Geillinger; Katja Kuhlmann; Helmut E Meyer; Hannelore Daniel; Martin Eisenacher; Britta Spanier
Dynamic changes of the Caenorhabditis elegans proteome during ontogenesis assessed by quantitative analysis with 15N metabolic labeling.
Journal of proteome research 2012;11(9):4594-604.
2012: Jürgen Stolz; Hannelore Daniel
A celebration of 100 years of vitamin research but time to revitalise the science.
The British journal of nutrition 2012;108(4):574-6.
2012: Susanne Krug; Jan Krumsiek; Burkhard Luy; Franco Moritz; Uwe Oeh; Cornelia Prehn; Johannes Raffler; Manuela J Rist; Werner Römisch-Margl; Manuela Sailer; philippe schmitt-kopplin; Thomas Skurk; Ferdinand Stückler; Karsten Suhre; Wilfried Szymczak; Fabian J Theis; Ralf Zimmermann; Karl-Heinz Engel; Thomas Frank; Hans Hauner; Thomas Hofmann; Fritz Huber; Gabi Kastenmüller; Werner Kremer; Jerzy Adamski; Hannelore Daniel
The dynamic range of the human metabolome revealed by challenges.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(6):2607-19.
2012: Ann-Kristin Petersen; Volker Pfahlert; Johannes Raffler; Manuela J Rist; Werner Römisch-Margl; Nilesh J Samani; Thomas Skurk; Klaus Stark; Karsten Suhre; Maciej Tomaszewski; H-Erich Wichmann; Jerzy Adamski; Hannelore Daniel; Hans Dieplinger; Angela Döring; Christian Gieger; Hans Hauner; Christian Hengstenberg; Fritz Huber; Thomas Illig; Bernhard M Kaess; Hans Robert Kalbitzer; Werner Kremer; Florian Kronenberg; Susanne Krug; Muntaser D Musameh; Christopher P Nelson; Annette Peters; Gabi Kastenmüller
Genetic associations with lipoprotein subfractions provide information on their biological nature.
Human molecular genetics 2012;21(6):1433-43.
2012: Charles Desmarchelier; Gerhard Jahreis; Sylvia Keller; Manuela Sailer; Christoph Dahlhoff; Hannelore Daniel
C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia.
BMC genomics 2012;13():84.
2012: Gregor Grünz; Kerstin Haas; Martin Klingenspor; Sabine E Kulling; Sebastian Soukup; Hannelore Daniel; Britta Spanier
Structural features and bioavailability of four flavonoids and their implications for lifespan-extending and antioxidant actions in C. elegans.
Mechanisms of ageing and development 2012;133(1):1-10.
2011: Anna E Groebner; Heinrich H D Meyer; Horst D Reichenbach; Isabel Rubio-Aliaga; Stefan Bauersachs; Mathias Büttner; Hannelore Daniel; Eckhard Wolf; Valeri Zakhartchenko; Susanne E Ulbrich
Reduced amino acids in the bovine uterine lumen of cloned versus in vitro fertilized pregnancies prior to implantation.
Cellular reprogramming 2011;13(5):403-10.
2011: Anna-Maria Nässl; Isabel Rubio-Aliaga; Henning Fenselau; Gabor Kottra; Mena Katharina Marth; Hannelore Daniel
Amino acid absorption and homeostasis in mice lacking the intestinal peptide transporter PEPT1.
American journal of physiology. Gastrointestinal and liver physiology 2011;301(1):G128-37.
2011: Anna E Groebner; Heinrich H D Meyer; Horst D Reichenbach; Isabel Rubio-Aliaga; Katy Schulke; Hannelore Daniel; Eckhard Wolf; Susanne E Ulbrich
Increase of essential amino acids in the bovine uterine lumen during preimplantation development.
Reproduction (Cambridge, England) 2011;141(5):685-95.
2011: Melina Claussnitzer; Thomas Skurk; Hans Hauner; Hannelore Daniel; Manuela J Rist
Effect of flavonoids on basal and insulin-stimulated 2-deoxyglucose uptake in adipocytes.
Molecular nutrition & food research 2011;55 Suppl 1():S26-34.
2011: Isabel Rubio-Aliaga; Manuela Sailer; Gerard A McLoughlin; Mark V Boekschoten; Marjan van Erk; Eva-Maria Bachmair; Evert M van Schothorst; Jaap Keijer; Susan L Coort; Chris Evelo; Mike joseph Gibney; Hannelore Daniel; Michael Müller; Robert Kleemann; Baukje de Roos; Lorraine Brennan
Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention.
Physiological genomics 2011;43(8):408-16.
2011: Anna-Maria Nässl; Isabel Rubio-Aliaga; Manuela Sailer; Hannelore Daniel
The intestinal peptide transporter PEPT1 is involved in food intake regulation in mice fed a high-protein diet.
PloS one 2011;6(10):e26407.
2011: Jacqueline Benner; Hannelore Daniel; Britta Spanier
A glutathione peroxidase, intracellular peptidases and the TOR complexes regulate peptide transporter PEPT-1 in C. elegans.
PloS one 2011;6(9):e25624.
2011: Nicole J W de Wit; Mark V Boekschoten; Eva-Maria Bachmair; Guido J E J Hooiveld; Philip J de Groot; Isabel Rubio-Aliaga; Hannelore Daniel; Michael Müller
Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice.
PloS one 2011;6(4):e19145.
2010: Britta Spanier; Isabel Rubio-Aliaga; Hao Hu; Hannelore Daniel
Altered signalling from germline to intestine pushes daf-2;pept-1 Caenorhabditis elegans into extreme longevity.
Aging cell 2010;9(4):636-46.
2010: Isabel Winkelmann; Daniela Diehl; Doris Oesterle; Hannelore Daniel; Uwe Wenzel
Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice.
Molecular nutrition & food research 2010;54 Suppl 2():S184-95.
2010: Tanja Heidler; Kai Hartwig; Hannelore Daniel; Uwe Wenzel
Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1.
Biogerontology 2010;11(2):183-95.
2010: A Nickel; U Klein; D Weitz; Hannelore Daniel
L-Proline transport into renal OK epithelial cells: a second renal proline transport system is induced by amino acid deprivation.
Amino acids 2010;38(3):753-61.
2010: A Romano; A Barca; Gabor Kottra; Hannelore Daniel; Carlo Storelli; Tiziano Verri
Functional expression of SLC15 peptide transporters in rat thyroid follicular cells.
Molecular and cellular endocrinology 2010;315(1-2):174-81.
2009: Helga Frank; Julia Graf; Juliane Graf; Ulrike Amann-Gassner; Renate Bratke; Hannelore Daniel; Uwe Heemann; Hans Hauner
Effect of short-term high-protein compared with normal-protein diets on renal hemodynamics and associated variables in healthy young men.
The American journal of clinical nutrition 2009;90(6):1509-16.
2009: Sabine Buhner; Qin Li; Sheila Vignali; Giovanni Barbara; Roberto De Giorgio; Vincenzo Stanghellini; Cesare Cremon; Friedrich J Zeller; Rupert Langer; Hannelore Daniel; Klaus Michel; Michael Schemann
Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome.
Gastroenterology 2009;137(4):1425-34.
2009: Kai Hartwig; Tanja Heidler; Jan Moch; Hannelore Daniel; Uwe Wenzel
Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis.
Genes & nutrition 2009;4(1):59-67.
2009: Alexander Nickel; Gabor Kottra; G Schmidt; J Danier; T Hofmann; Hannelore Daniel
Characteristics of transport of selenoamino acids by epithelial amino acid transporters.
Chemico-biological interactions 2009;177(3):234-41.
2009: Gabor Kottra; Isabelle M Frey; Hannelore Daniel
Inhibition of intracellular dipeptide hydrolysis uncovers large outward transport currents of the peptide transporter PEPT1 in Xenopus oocytes.
Pflügers Archiv : European journal of physiology 2009;457(4):809-20.
2009: Britta Spanier; Katrin Lasch; Silke Marsch; Jacqueline Benner; Wenjuan Liao; Hao Hu; Hermine Kienberger; Wolfgang Eisenreich; Hannelore Daniel
How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans.
PloS one 2009;4(7):e6279.
2008: Hannelore Daniel; Christian Andre Drevon; Ulla I Klein; Robert Kleemann; Ben van Ommen
The challenges for molecular nutrition research 3: comparative nutrigenomics research as a basis for entering the systems level.
Genes & nutrition 2008;3(3-4):101-6.
2008: Ilka Knütter; Claudia Wollesky; Gabor Kottra; Martin G Hahn; Wiebke Fischer; Katja Zebisch; Reinhard H H Neubert; Hannelore Daniel; Matthias Brandsch
Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited.
The Journal of pharmacology and experimental therapeutics 2008;327(2):432-41.
2008: Isabel Rubio-Aliaga; Hannelore Daniel
Peptide transporters and their roles in physiological processes and drug disposition.
Xenobiotica; the fate of foreign compounds in biological systems 2008;38(7-8):1022-42.
2008: Daniel Harder; Jürgen Stolz; Fabio Casagrande; Petr Obrdlik; Dietmar Weitz; Dimitrios Fotiadis; Hannelore Daniel
DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli.
The FEBS journal 2008;275(13):3290-8.
2008: M Emília Juan; Uwe Wenzel; Hannelore Daniel; Joana M Planas
Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells.
Journal of agricultural and food chemistry 2008;56(12):4813-8.
2008: Baukje de Roos; Susan J Duthie; Abigael C J Polley; Francis Mulholland; Freek G Bouwman; Carolin Heim; Garry J Rucklidge; Ian Johnson; Edwin C M Mariman; Hannelore Daniel; Ruan M Elliott
Proteomic methodological recommendations for studies involving human plasma, platelets, and peripheral blood mononuclear cells.
Journal of proteome research 2008;7(6):2280-90.
2008: Isabel Winkelmann; Anna-Maria Nässl; Hannelore Daniel; Uwe Wenzel
Proteome response in HT-29 human colorectal cancer cells to two apoptosis-inducing compounds with different mode of action.
International journal of cancer. Journal international du cancer 2008;122(10):2223-32.
2008: M Emília Juan; Uwe Wenzel; Hannelore Daniel; Joana M Planas
Erythrodiol, a natural triterpenoid from olives, has antiproliferative and apoptotic activity in HT-29 human adenocarcinoma cells.
Molecular nutrition & food research 2008;52(5):595-9.
2008: Gerald Rimbach; Christine Boesch-Saadatmandi; Jan Frank; Dagmar Fuchs; Uwe Wenzel; Hannelore Daniel; Wendy L Hall; Peter D Weinberg
Dietary isoflavones in the prevention of cardiovascular disease--a molecular perspective.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(4):1308-19.
2008: K Buehlmeyer; F Doering; Hannelore Daniel; Birgit Kindermann; T Schulz; H Michna
Alteration of gene expression in rat colon mucosa after exercise.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2008;190(1):71-80.
2007: Dagmar Fuchs; Katerina Vafeiadou; Wendy L Hall; Hannelore Daniel; Christine M Williams; Joyce H Schroot; Uwe Wenzel
Proteomic biomarkers of peripheral blood mononuclear cells obtained from postmenopausal women undergoing an intervention with soy isoflavones.
The American journal of clinical nutrition 2007;86(5):1369-75.
2007: Ilka Knütter; Bianka Hartrodt; Géza Tóth; Attila Keresztes; Gabor Kottra; Carmen Mrestani-Klaus; Ilona Born; Hannelore Daniel; Klaus Neubert; Matthias Brandsch
Synthesis and characterization of a new and radiolabeled high-affinity substrate for H+/peptide cotransporters.
The FEBS journal 2007;274(22):5905-14.
2007: Dagmar Fuchs; Regina Piller; Jakob Linseisen; Hannelore Daniel; Uwe Wenzel
The human peripheral blood mononuclear cell proteome responds to a dietary flaxseed-intervention and proteins identified suggest a protective effect in atherosclerosis.
Proteomics 2007;7(18):3278-88.
2007: Gabor Kottra; Hannelore Daniel
Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake.
The Journal of pharmacology and experimental therapeutics 2007;322(2):829-35.
2007: Isabel Winkelmann; Daniela Diehl; Doris Oesterle; Hannelore Daniel; Uwe Wenzel
The suppression of aberrant crypt multiplicity in colonic tissue of 1,2-dimethylhydrazine-treated C57BL/6J mice by dietary flavone is associated with an increased expression of Krebs cycle enzymes.
Carcinogenesis 2007;28(7):1446-54.
2007: Dagmar Fuchs; Barbara Dirscherl; Joyce H Schroot; Hannelore Daniel; Uwe Wenzel
Proteome analysis suggests that mitochondrial dysfunction in stressed endothelial cells is reversed by a soy extract and isolated isoflavones.
Journal of proteome research 2007;6(6):2132-42.
2007: Anna Shkoda; Tanja Werner; Hannelore Daniel; Manuela Gunckel; Gerhard Rogler; Dirk Haller
Differential protein expression profile in the intestinal epithelium from patients with inflammatory bowel disease.
Journal of proteome research 2007;6(3):1114-25.
2007: Katrin Lohner; Kerstin Schnäbele; Hannelore Daniel; Doris Oesterle; Gerhard Rechkemmer; Martin Göttlicher; Uwe Wenzel
Flavonoids alter P-gp expression in intestinal epithelial cells in vitro and in vivo.
Molecular nutrition & food research 2007;51(3):293-300.
2007: Isabelle M Frey; Isabel Rubio-Aliaga; Anne Siewert; Daniela Sailer; Alexei Drobyshev; Johannes Beckers; Martin Hrabé De Angelis; Julie Aubert; Avner Bar-Hen; Oliver Fiehn; Hans M Eichinger; Hannelore Daniel
Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice.
Physiological genomics 2007;28(3):301-10.
2007: Dietmar Weitz; Daniel Harder; Fabio Casagrande; Dimitrios Fotiadis; Petr Obrdlik; Bela Kelety; Hannelore Daniel
Functional and structural characterization of a prokaryotic peptide transporter with features similar to mammalian PEPT1.
The Journal of biological chemistry 2007;282(5):2832-9.
2007: Anna Shkoda; Pedro A Ruiz; Hannelore Daniel; Sandra Kim; Gerhard Rogler; Ryan Sartor; Dirk Haller
Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation.
Gastroenterology 2007;132(1):190-207.
2006: Annegret Biegel; Ilka Knütter; Bianka Hartrodt; Sabine Gebauer; Stephan Theis; P Luckner; Gabor Kottra; M Rastetter; K Zebisch; Iris Thondorf; Hannelore Daniel; Klaus Neubert; Matthias Brandsch
The renal type H+/peptide symporter PEPT2: structure-affinity relationships.
Amino acids 2006;31(2):137-56.
2006: Isabelle M Frey; Isabel Rubio-Aliaga; Martina Klempt; Eckhard Wolf; Hannelore Daniel
Phenotype analysis of mice deficient in the peptide transporter PEPT2 in response to alterations in dietary protein intake.
Pflügers Archiv : European journal of physiology 2006;452(3):300-6.
2006: Hannelore Daniel; Britta Spanier; Gabor Kottra; Dietmar Weitz
From bacteria to man: archaic proton-dependent peptide transporters at work.
Physiology (Bethesda, Md.) 2006;21():93-102.
2006: Manuela J Rist; Uwe Wenzel; Hannelore Daniel
Nutrition and food science go genomic.
Trends in biotechnology 2006;24(4):172-8.
2006: Alessandro Romano; Gabor Kottra; Amilcare Barca; Natascia Tiso; Michele Maffia; Francesco Argenton; Hannelore Daniel; Carlo Storelli; Tiziano Verri
High-affinity peptide transporter PEPT2 (SLC15A2) of the zebrafish Danio rerio: functional properties, genomic organization, and expression analysis.
Physiological genomics 2006;24(3):207-17.
2006: Maja Klapper; Hannelore Daniel; Frank Döring
Cytosolic COOH terminus of the peptide transporter PEPT2 is involved in apical membrane localization of the protein.
American journal of physiology. Cell physiology 2006;290(2):C472-83.
2006: Dagmar Fuchs; Barbara Dirscherl; Joyce H Schroot; Hannelore Daniel; Uwe Wenzel
Soy extract has different effects compared with the isolated isoflavones on the proteome of homocysteine-stressed endothelial cells.
Molecular nutrition & food research 2006;50(1):58-69.
2006: Roberto Ambra; Gerald Rimbach; Sonia de Pascual-Teresa; Dagmar Fuchs; Uwe Wenzel; Hannelore Daniel; Fabio Virgili
Genistein affects the expression of genes involved in blood pressure regulation and angiogenesis in primary human endothelial cells.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2006;16(1):35-43.
2005: Uwe Wenzel; Alexander Nickel; Hannelore Daniel
Increased mitochondrial palmitoylcarnitine/carnitine countertransport by flavone causes oxidative stress and apoptosis in colon cancer cells.
Cellular and molecular life sciences : CMLS 2005;62(24):3100-5.
2005: Ladislav Raschka; Hannelore Daniel
Mechanisms underlying the effects of inulin-type fructans on calcium absorption in the large intestine of rats.
Bone 2005;37(5):728-35.
2005: Anne Rühl; Susanne Hoppe; Isabelle M Frey; Hannelore Daniel; Michael Schemann
Functional expression of the peptide transporter PEPT2 in the mammalian enteric nervous system.
The Journal of comparative neurology 2005;490(1):1-11.
2005: Dagmar Fuchs; Isabel Winkelmann; Ian Johnson; Edwin C M Mariman; Uwe Wenzel; Hannelore Daniel
Proteomics in nutrition research: principles, technologies and applications.
The British journal of nutrition 2005;94(3):302-14.
2005: Linda Metzner; Gabor Kottra; Klaus Neubert; Hannelore Daniel; Matthias Brandsch
Serotonin, L-tryptophan, and tryptamine are effective inhibitors of the amino acid transport system PAT1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(11):1468-73.
2005: Ladislav Raschka; Hannelore Daniel
Diet composition and age determine the effects of inulin-type fructans on intestinal calcium absorption in rat.
European journal of nutrition 2005;44(6):360-4.
2005: Uwe Wenzel; Alexander Nickel; Hannelore Daniel
Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products.
International journal of cancer. Journal international du cancer 2005;116(2):236-42.
2005: Frank Döring; Roland Schmitt; Wanja M Bernhardt; Maja Klapper; Sebastian Bachmann; Hannelore Daniel; David A Groneberg
Hypothyroidism induces expression of the peptide transporter PEPT2.
Biological chemistry 2005;386(8):785-90.
2005: Dagmar Fuchs; Petra Erhard; Gerald Rimbach; Hannelore Daniel; Uwe Wenzel
Genistein blocks homocysteine-induced alterations in the proteome of human endothelial cells.
Proteomics 2005;5(11):2808-18.
2005: Birgit Kindermann; Frank Döring; Dagmar Fuchs; Michael W Pfaffl; Hannelore Daniel
Effects of increased cellular zinc levels on gene and protein expression in HT-29 cells.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2005;18(3):243-53.
2005: Uwe Wenzel; Alexander Nickel; Hannelore Daniel
Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis.
The Journal of nutrition 2005;135(6):1510-4.
2005: Birgit Kindermann; Frank Döring; Jan Budczies; Hannelore Daniel
Zinc-sensitive genes as potential new target genes of the metal transcription factor-1 (MTF-1).
Biochemistry and cell biology = Biochimie et biologie cellulaire 2005;83(2):221-9.
2005: Martin Foltz; Manuela Mertl; Veronika Dietz; Michael Boll; Gabor Kottra; Hannelore Daniel
Kinetics of bidirectional H+ and substrate transport by the proton-dependent amino acid symporter PAT1.
The Biochemical journal 2005;386(Pt 3):607-16.
2005: Uwe Wenzel; Alexander Nickel; Hannelore Daniel
alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.
Apoptosis : an international journal on programmed cell death 2005;10(2):359-68.
2005: Dagmar Fuchs; Petra Erhard; Rufus Turner; Gerald Rimbach; Hannelore Daniel; Uwe Wenzel
Genistein reverses changes of the proteome induced by oxidized-LDL in EA.hy 926 human endothelial cells.
Journal of proteome research 2005;4(2):369-76.
2005: Dagmar Fuchs; Sonia de Pascual-Teresa; Gerald Rimbach; Fabio Virgili; Roberto Ambra; Rufus Turner; Hannelore Daniel; Uwe Wenzel
Proteome analysis for identification of target proteins of genistein in primary human endothelial cells stressed with oxidized LDL or homocysteine.
European journal of nutrition 2005;44(2):95-104.
2005: Heike tom Dieck; Frank Döring; Dagmar Fuchs; Hans-Peter Roth; Hannelore Daniel
Transcriptome and proteome analysis identifies the pathways that increase hepatic lipid accumulation in zinc-deficient rats.
The Journal of nutrition 2005;135(2):199-205.
2005: Uwe Wenzel; Katrin Schoberl; Katrin Lohner; Hannelore Daniel
Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells.
Journal of cellular physiology 2005;202(2):379-90.
2004: Catriona M H Anderson; Danielle S Grenade; Michael Boll; Martin Foltz; Katherine A Wake; David J Kennedy; Lars K Munck; Seiji Miyauchi; Peter M Taylor; Frederick Charles Campbell; Bjarne G Munck; Hannelore Daniel; Vadivel Ganapathy; David T Thwaites
H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat.
Gastroenterology 2004;127(5):1410-22.
2004: Martin Foltz; Michael Boll; Ladislav Raschka; Gabor Kottra; Hannelore Daniel
A novel bifunctionality: PAT1 and PAT2 mediate electrogenic proton/amino acid and electroneutral proton/fatty acid symport.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1758-60.
2004: Martin Foltz; Carmen Oechsler; Michael Boll; Gabor Kottra; Hannelore Daniel
Substrate specificity and transport mode of the proton-dependent amino acid transporter mPAT2.
European journal of biochemistry / FEBS 2004;271(16):3340-7.
2004: Angelika Herzog; Birgit Kindermann; Frank Döring; Hannelore Daniel; Uwe Wenzel
Pleiotropic molecular effects of the pro-apoptotic dietary constituent flavone in human colon cancer cells identified by protein and mRNA expression profiling.
Proteomics 2004;4(8):2455-64.
2004: Martin Foltz; Antje Meyer; Stephan Theis; Hans-Ulrich Demuth; Hannelore Daniel
A rapid in vitro screening for delivery of peptide-derived peptidase inhibitors as potential drug candidates via epithelial peptide transporters.
The Journal of pharmacology and experimental therapeutics 2004;310(2):695-702.
2004: Hannelore Daniel; Heike tom Dieck
Nutrient-gene interactions: a single nutrient and hundreds of target genes.
Biological chemistry 2004;385(7):571-83.
2004: Uwe Wenzel; Angelika Herzog; Sabine Kuntz; Hannelore Daniel
Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells.
Proteomics 2004;4(7):2160-74.
2004: David A Groneberg; Isabel Rubio-Aliaga; Monika Nickolaus; Frank Döring; Axel Fischer; Hannelore Daniel
Direct visualization of peptide uptake activity in the central nervous system of the rat.
Neuroscience letters 2004;364(1):32-6.
2004: Uwe Wenzel; Alexander Nickel; Sabine Kuntz; Hannelore Daniel
Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions.
Carcinogenesis 2004;25(5):703-12.
2004: Angelika Herzog; Sabine Kuntz; Hannelore Daniel; Uwe Wenzel
Identification of biomarkers for the initiation of apoptosis in human preneoplastic colonocytes by proteome analysis.
International journal of cancer. Journal international du cancer 2004;109(2):220-9.
2004: Hannelore Daniel; Gabor Kottra
The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology.
Pflügers Archiv : European journal of physiology 2004;447(5):610-8.
2004: Michael Boll; Hannelore Daniel; Bruno Gasnier
The SLC36 family: proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis.
Pflügers Archiv : European journal of physiology 2004;447(5):776-9.
2004: Isabel Rubio-Aliaga; Michael Boll; Daniela Vogt Weisenhorn; Martin Foltz; Gabor Kottra; Hannelore Daniel
The proton/amino acid cotransporter PAT2 is expressed in neurons with a different subcellular localization than its paralog PAT1.
The Journal of biological chemistry 2004;279(4):2754-60.
2004: Hannelore Daniel
Molecular and integrative physiology of intestinal peptide transport.
Annual review of physiology 2004;66():361-84.
2004: Ilka Knütter; Bianka Hartrodt; Stephan Theis; Martin Foltz; Matthias Rastetter; Hannelore Daniel; Klaus Neubert; Matthias Brandsch
Analysis of the transport properties of side chain modified dipeptides at the mammalian peptide transporter PEPT1.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(1):61-7.
2004: Birgit Kindermann; Frank Döring; Michael W Pfaffl; Hannelore Daniel
Identification of genes responsive to intracellular zinc depletion in the human colon adenocarcinoma cell line HT-29.
The Journal of nutrition 2004;134(1):57-62.
2003: Uwe Wenzel; Sabine Kuntz; Hannelore Daniel
Nitric oxide levels in human preneoplastic colonocytes determine their susceptibility toward antineoplastic agents.
Molecular pharmacology 2003;64(6):1494-502.
2003: Uwe Wenzel; Sabine Kuntz; Ulrike Jambor De Sousa; Hannelore Daniel
Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions.
International journal of cancer. Journal international du cancer 2003;106(5):666-75.
2003: Tiziano Verri; Gabor Kottra; Alessandro Romano; Natascia Tiso; Mark Peric; Michele Maffia; Michael Boll; Francesco Argenton; Hannelore Daniel; Carlo Storelli
Molecular and functional characterisation of the zebrafish (Danio rerio) PEPT1-type peptide transporter.
FEBS letters 2003;549(1-3):115-22.
2003: Michael Boll; Martin Foltz; Catriona M H Anderson; Carmen Oechsler; Gabor Kottra; David T Thwaites; Hannelore Daniel
Substrate recognition by the mammalian proton-dependent amino acid transporter PAT1.
Molecular membrane biology 2003;20(3):261-9.
2003: Michael Boll; Martin Foltz; Isabel Rubio-Aliaga; Hannelore Daniel
A cluster of proton/amino acid transporter genes in the human and mouse genomes.
Genomics 2003;82(1):47-56.
2003: Isabel Rubio-Aliaga; Isabelle M Frey; Michael Boll; David A Groneberg; Hans M Eichinger; Rudi Balling; Hannelore Daniel
Targeted disruption of the peptide transporter Pept2 gene in mice defines its physiological role in the kidney.
Molecular and cellular biology 2003;23(9):3247-52.
2003: Hannelore Daniel; Isabel Rubio-Aliaga
An update on renal peptide transporters.
American journal of physiology. Renal physiology 2003;284(5):F885-92.
2003: Heike tom Dieck; Frank Döring; Hans-Peter Roth; Hannelore Daniel
Changes in rat hepatic gene expression in response to zinc deficiency as assessed by DNA arrays.
The Journal of nutrition 2003;133(4):1004-10.
2003: Michele Maffia; Antonia Rizzello; Raffaele Acierno; Tiziano Verri; M Rollo; Antonio Danieli; F Döring; Hannelore Daniel; Carlo Storelli
Characterisation of intestinal peptide transporter of the Antarctic haemoglobinless teleost Chionodraco hamatus.
The Journal of experimental biology 2003;206(Pt 4):705-14.
2002: Gabor Kottra; Adelmar Stamfort; Hannelore Daniel
PEPT1 as a paradigm for membrane carriers that mediate electrogenic bidirectional transport of anionic, cationic, and neutral substrates.
The Journal of biological chemistry 2002;277(36):32683-91.
2002: Isabel Rubio-Aliaga; Hannelore Daniel
Mammalian peptide transporters as targets for drug delivery.
Trends in pharmacological sciences 2002;23(9):434-40.
2002: David A Groneberg; Frank Döring; Monika Nickolaus; Hannelore Daniel; Axel Fischer
Renal assimilation of short chain peptides: visualization of tubular peptide uptake.
Pharmaceutical research 2002;19(8):1209-14.
2002: Ilka Knütter; Isabel Rubio-Aliaga; Michael Boll; Gerd Hause; Hannelore Daniel; Klaus Neubert; Matthias Brandsch
H+-peptide cotransport in the human bile duct epithelium cell line SK-ChA-1.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(1):G222-9.
2002: Michael Boll; Martin Foltz; Isabel Rubio-Aliaga; Gabor Kottra; Hannelore Daniel
Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters.
The Journal of biological chemistry 2002;277(25):22966-73.
2002: Hannelore Daniel
Genomics and proteomics: importance for the future of nutrition research.
The British journal of nutrition 2002;87 Suppl 2():S305-11.
2002: Uwe Wenzel; Sabine Kuntz; Simone Diestel; Hannelore Daniel
PEPT1-mediated cefixime uptake into human intestinal epithelial cells is increased by Ca2+ channel blockers.
Antimicrobial agents and chemotherapy 2002;46(5):1375-80.
2002: David A Groneberg; Frank Döring; Stephan Theis; Monika Nickolaus; Axel Fischer; Hannelore Daniel
Peptide transport in the mammary gland: expression and distribution of PEPT2 mRNA and protein.
American journal of physiology. Endocrinology and metabolism 2002;282(5):E1172-9.
2002: F Döring; C Martini; J Walter; Hannelore Daniel
Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function.
The Journal of membrane biology 2002;186(2):55-62.
2002: Stephan Theis; Ilka Knutter; Bianka Hartrodt; Matthias Brandsch; Gabor Kottra; Klaus Neubert; Hannelore Daniel
Synthesis and characterization of high affinity inhibitors of the H+/peptide transporter PEPT2.
The Journal of biological chemistry 2002;277(9):7287-92.
2002: David A Groneberg; PAUL EYNOTT; F Döring; Q Thai Dinh; Timothy Oates; Peter J Barnes; K Fan Chung; Hannelore Daniel; A Fischer
Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung.
Thorax 2002;57(1):55-60.
2002: Stephan Theis; Bianka Hartrodt; Gabor Kottra; Klaus Neubert; Hannelore Daniel
Defining minimal structural features in substrates of the H(+)/peptide cotransporter PEPT2 using novel amino acid and dipeptide derivatives.
Molecular pharmacology 2002;61(1):214-21.
2001: Gabor Kottra; Hannelore Daniel
Bidirectional electrogenic transport of peptides by the proton-coupled carrier PEPT1 in Xenopus laevis oocytes: its asymmetry and symmetry.
The Journal of physiology 2001;536(Pt 2):495-503.
2001: Uwe Wenzel; Sabine Kuntz; Hannelore Daniel
Flavonoids with epidermal growth factor-receptor tyrosine kinase inhibitory activity stimulate PEPT1-mediated cefixime uptake into human intestinal epithelial cells.
The Journal of pharmacology and experimental therapeutics 2001;299(1):351-7.
2001: David A Groneberg; F Döring; PAUL EYNOTT; A Fischer; Hannelore Daniel
Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(3):G697-704.
2001: Stephan Theis; Frank Döring; Hannelore Daniel
Expression of the myc/His-tagged human peptide transporter hPEPT1 in yeast for protein purification and functional analysis.
Protein expression and purification 2001;22(3):436-42.
2001: David A Groneberg; Frank Döring; Monika Nickolaus; Hannelore Daniel; Axel Fischer
Expression of PEPT2 peptide transporter mRNA and protein in glial cells of rat dorsal root ganglia.
Neuroscience letters 2001;304(3):181-4.
2001: Ilka Knütter; Stephan Theis; Bianka Hartrodt; Ilona Born; Matthias Brandsch; Hannelore Daniel; Klaus Neubert
A novel inhibitor of the mammalian peptide transporter PEPT1.
Biochemistry 2001;40(14):4454-8.
2001: Uwe Wenzel; B Meissner; F Döring; Hannelore Daniel
PEPT1-mediated uptake of dipeptides enhances the intestinal absorption of amino acids via transport system b(0,+).
Journal of cellular physiology 2001;186(2):251-9.
2001: David A Groneberg; Monika Nickolaus; J Springer; Frank Döring; Hannelore Daniel; Axel Fischer
Localization of the peptide transporter PEPT2 in the lung: implications for pulmonary oligopeptide uptake.
The American journal of pathology 2001;158(2):707-14.
2000: Tiziano Verri; Michele Maffia; Antonio Danieli; martina herget; U Wenzel; Hannelore Daniel; Carlo Storelli
Characterisation of the H(+)/peptide cotransporter of eel intestinal brush-border membranes.
The Journal of experimental biology 2000;203(Pt 19):2991-3001.
2000: Isabel Rubio-Aliaga; Michael Boll; Hannelore Daniel
Cloning and characterization of the gene encoding the mouse peptide transporter PEPT2.
Biochemical and biophysical research communications 2000;276(2):734-41.
2000: Uwe Wenzel; S Kuntz; M D Brendel; Hannelore Daniel
Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells.
Cancer research 2000;60(14):3823-31.
2000: M B Engfer; B Stahl; Berndt Finke; G Sawatzki; Hannelore Daniel
Human milk oligosaccharides are resistant to enzymatic hydrolysis in the upper gastrointestinal tract.
The American journal of clinical nutrition 2000;71(6):1589-96.
1999: Uwe Wenzel; Daniela Diehl; martina herget; S Kuntz; Hannelore Daniel
Regulation of the high-affinity H+/peptide cotransporter in renal LLC-PK1 cells.
Journal of cellular physiology 1999;178(3):341-8.
1998: Uwe Wenzel; Daniela Diehl; martina herget; Hannelore Daniel
Endogenous expression of the renal high-affinity H+-peptide cotransporter in LLC-PK1 cells.
The American journal of physiology 1998;275(6 Pt 1):C1573-9.
1998: Frank Döring; Maja Klapper; Stephan Theis; Hannelore Daniel
Use of the glyceraldehyde-3-phosphate dehydrogenase promoter for production of functional mammalian membrane transport proteins in the yeast Pichia pastoris.
Biochemical and biophysical research communications 1998;250(2):531-5.
1998: Frank Döring; J Will; S Amasheh; Wolfgang Clauss; H Ahlbrecht; Hannelore Daniel
Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter.
The Journal of biological chemistry 1998;273(36):23211-8.
1998: Frank Döring; J Walter; J Will; Melanie Foecking; M Boll; S Amasheh; Wolfgang Clauss; Hannelore Daniel
Delta-aminolevulinic acid transport by intestinal and renal peptide transporters and its physiological and clinical implications.
The Journal of clinical investigation 1998;101(12):2761-7.
1998: Frank Döring; T Michel; A Rösel; Monika Nickolaus; Hannelore Daniel
Expression of the mammalian renal peptide transporter PEPT2 in the yeast Pichia pastoris and applications of the yeast system for functional analysis.
Molecular membrane biology 1998;15(2):79-88.
1997: S Amasheh; U Wenzel; Wolf-Michael Weber; Wolfgang Clauss; Hannelore Daniel
Electrophysiological analysis of the function of the mammalian renal peptide transporter expressed in Xenopus laevis oocytes.
The Journal of physiology 1997;504 ( Pt 1)():169-74.
1997: Hannelore Daniel; martina herget
Cellular and molecular mechanisms of renal peptide transport.
The American journal of physiology 1997;273(1 Pt 2):F1-8.
1997: Frank Döring; Stephan Theis; Hannelore Daniel
Expression and functional characterization of the mammalian intestinal peptide transporter PepT1 in the methylotropic yeast Pichia pastoris.
Biochemical and biophysical research communications 1997;232(3):656-62.
1997: Hannelore Daniel
First insights into the operational mode of epithelial peptide transporters.
The Journal of physiology 1997;498 ( Pt 3)():561.
1997: S Amasheh; U Wenzel; M Boll; D Dorn; W Weber; Wolfgang Clauss; Hannelore Daniel
Transport of charged dipeptides by the intestinal H+/peptide symporter PepT1 expressed in Xenopus laevis oocytes.
The Journal of membrane biology 1997;155(3):247-56.
1996: Frank Döring; D Dorn; U Bachfischer; S Amasheh; martina herget; Hannelore Daniel
Functional analysis of a chimeric mammalian peptide transporter derived from the intestinal and renal isoforms.
The Journal of physiology 1996;497 ( Pt 3)():773-9.
1996: Hannelore Daniel
Function and molecular structure of brush border membrane peptide/H+ symporters.
The Journal of membrane biology 1996;154(3):197-203.
1996: U Wenzel; I Gebert; H Weintraut; Wolf-Michael Weber; Wolfgang Clauss; Hannelore Daniel
Transport characteristics of differently charged cephalosporin antibiotics in oocytes expressing the cloned intestinal peptide transporter PepT1 and in human intestinal Caco-2 cells.
The Journal of pharmacology and experimental therapeutics 1996;277(2):831-9.
1996: M Boll; martina herget; M Wagener; Wolf-Michael Weber; Daniel Markovich; Jürg Biber; Wolfgang Clauss; Heini Murer; Hannelore Daniel
Expression cloning and functional characterization of the kidney cortex high-affinity proton-coupled peptide transporter.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):284-9.
1995: U Wenzel; D T Thwaites; Hannelore Daniel
Stereoselective uptake of beta-lactam antibiotics by the intestinal peptide transporter.
British journal of pharmacology 1995;116(7):3021-7.
1995: A Scholl; M Gent; Hannelore Daniel
Alanine transport across the human placental brush border membrane and the role of SH groups in carrier function.
Zeitschrift für Ernährungswissenschaft 1995;34(4):285-92.
1995: Hannelore Daniel; S A Adibi
Selective effect of zinc on uphill transport of oligopeptides into kidney brush border membrane vesicles.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(11):1112-7.
1995: M Boll; Hannelore Daniel
Target size analysis of the peptide/H(+)-symporter in kidney brush-border membranes.
Biochimica et biophysica acta 1995;1233(2):145-52.
1994: M Ries; U Wenzel; Hannelore Daniel
Transport of cefadroxil in rat kidney brush-border membranes is mediated by two electrogenic H+-coupled systems.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1327-33.
1994: M Boll; Daniel Markovich; Wolf-Michael Weber; H Korte; Hannelore Daniel; Heini Murer
Expression cloning of a cDNA from rabbit small intestine related to proton-coupled transport of peptides, beta-lactam antibiotics and ACE-inhibitors.
Pflügers Archiv : European journal of physiology 1994;429(1):146-9.
1994: J Stein; Hannelore Daniel; E Whang; U Wenzel; A Hahn; G Rehner
Rapid postabsorptive metabolism of nicotinic acid in rat small intestine may affect transport by metabolic trapping.
The Journal of nutrition 1994;124(1):61-6.
1992: Hannelore Daniel; G I Rehner
Sodium-dependent transport of riboflavin in brush border membrane vesicles of rat small intestine is an electrogenic process.
The Journal of nutrition 1992;122(7):1454-61.
1991: A Hahn; Hannelore Daniel; G Rehner
Transport of pteroylglutamic acid into brush border membrane vesicles from rat small intestine is a partially carrier-mediated process.
Zeitschrift für Ernährungswissenschaft 1991;30(3):201-13.
1991: S Feder; Hannelore Daniel; G Rehner
In vivo kinetics of intestinal absorption of riboflavin in rats.
The Journal of nutrition 1991;121(1):72-9.
1990: Hannelore Daniel; M Vohwinkel; G Rehner
Effect of casein and beta-casomorphins on gastrointestinal motility in rats.
The Journal of nutrition 1990;120(3):252-7.
1989: Hannelore Daniel; C Fett; A Kratz
Demonstration and modification of intervillous pH profiles in rat small intestine in vitro.
The American journal of physiology 1989;257(4 Pt 1):G489-95.
1988: G T McEwan; Hannelore Daniel; C Fett; M N Burgess; M L Lucas
The effect of Escherichia coli STa enterotoxin and other secretagogues on mucosal surface pH of rat small intestine in vivo.
Proceedings of the Royal Society of London. Series B, Containing papers of a Biological character. Royal Society (Great Britain) 1988;234(1275):219-37.
1987: H Bartels; A Link; Hannelore Daniel; G Rehner
[Intestinal liberation and resorption of monosaccharides from carbohydrates of different degrees of polymerization. I. Relation between intestinal hydrolysis of carbohydrates and resorption of monosaccharides].
Zeitschrift für Ernährungswissenschaft 1987;26(3):179-93.