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Simone Danner

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Dorothee Abramowski; Estibaliz Capetillo-Zarate; Simone Danner; Sabine Rabe; Julia Reichwald; Takaomi C Saido; Dieter Staab; Dietmar R Thal; Ajeet Rijal Upadhaya; Karl-Heinz Wiederhold; Haruyasu Yamaguchi; Matthias Staufenbiel
Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology.
Martin C Herzig; Franziska Mayer; Giorgio Rovelli; Peter Schmid; Tatjana Schweizer; Carmen Barske; Michael Bidinosti; Simone Danner; Thomas Hafner; Daniela Stauffer; Christine Stemmelen; P Herman van der Putten; Nella Vidotto; Andreas Weiss; Derya R Shimshek
High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain.
Martin C Herzig; Klemens Kaupmann; Bernd Kinzel; Carine Kolly; Rainer R Kuhn; Matthias Mueller; Elke Persohn; Giorgio Rovelli; Peter Schmid; Christian R Schnell; Tatjana Schweizer; Federico Bolognani; Simone Danner; Armelle Grevot; Thomas Hafner; Christine Stemmelen; Martina Stirn; Diethilde Theil; Thomas J Troxler; P Herman van der Putten; Derya R Shimshek
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.

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All Publications

2012: Dorothee Abramowski; Estibaliz Capetillo-Zarate; Simone Danner; Sabine Rabe; Julia Reichwald; Takaomi C Saido; Dieter Staab; Dietmar R Thal; Ajeet Rijal Upadhaya; Karl-Heinz Wiederhold; Haruyasu Yamaguchi; Matthias Staufenbiel
Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(4):1273-83.
2012: Martin C Herzig; Franziska Mayer; Giorgio Rovelli; Peter Schmid; Tatjana Schweizer; Carmen Barske; Michael Bidinosti; Simone Danner; Thomas Hafner; Daniela Stauffer; Christine Stemmelen; P Herman van der Putten; Nella Vidotto; Andreas Weiss; Derya R Shimshek
High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain.
PloS one 2012;7(5):e36581.
2011: Martin C Herzig; Klemens Kaupmann; Bernd Kinzel; Carine Kolly; Rainer R Kuhn; Matthias Mueller; Elke Persohn; Giorgio Rovelli; Peter Schmid; Christian R Schnell; Tatjana Schweizer; Federico Bolognani; Simone Danner; Armelle Grevot; Thomas Hafner; Christine Stemmelen; Martina Stirn; Diethilde Theil; Thomas J Troxler; P Herman van der Putten; Derya R Shimshek
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.
Human molecular genetics 2011;20(21):4209-23.
2011: Christoph Wiessner; Mauro Zurini; Alain C Tissot; Karl-Heinz Wiederhold; Martin F Bachmann; Simone Danner; Peter Frey; Laura H Jacobson; Gary T Jennings; Rainer Lüönd; Anis Mir; Rainer Ortmann; Julia Reichwald; Matthias Staufenbiel
The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(25):9323-31.
2011: Claus Rieker; Markus A Ruegg; Heinrich Schell; Herman van der Putten; Samuel Barbieri; Cindy Boden; Simone Danner; Kumlesh K Dev; Philipp J Kahle; S Kauffmann; Iwona Ksiazek; Katja Lehnhoff; Derya R Shimshek
Neuropathology in mice expressing mouse alpha-synuclein.
PloS one 2011;6(9):e24834.
2004: Martin C Herzig; David T Winkler; Patrick Burgermeister; Michelle Pfeifer; Esther Kohler; Stephen D Schmidt; Simone Danner; Dorothee Abramowski; Christine Stürchler-Pierrat; Kurt Bürki; Sjoerd G van Duinen; Marion L C Maat-Schieman; Matthias Staufenbiel; Paul Mathews; Mathias Jucker
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
Nature neuroscience 2004;7(9):954-60.
2003: Margarita Diez; Simone Danner; Peter Frey; Bernd Sommer; Matthias Staufenbiel; Karl-Heinz Wiederhold; Tomas Hökfelt
Neuropeptide alterations in the hippocampal formation and cortex of transgenic mice overexpressing beta-amyloid precursor protein (APP) with the Swedish double mutation (APP23).
Neurobiology of disease 2003;14(3):579-94.
2002: Ursula Bodendorf; Simone Danner; Frauke Fischer; Muriel Stefani; Christine Sturchler-Pierrat; Karl-Heinz Wiederhold; Matthias Staufenbiel; Paolo Paganetti
Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.
Journal of neurochemistry 2002;80(5):799-806.
2001: Samuel Barbieri; Katja Hofele; Karl-Heinz Wiederhold; Alphonse Probst; C Mistl; Simone Danner; S Kauffmann; Bernd Sommer; Will Spooren; Markus Tolnay; Graeme Bilbe; Herman van der Putten
Mouse models of alpha-synucleinopathy and Lewy pathology. Alpha-synuclein expression in transgenic mice.
Advances in experimental medicine and biology 2001;487():147-67.
2000: Bernd Sommer; Samuel Barbieri; Katja Hofele; Karl-Heinz Wiederhold; Alphonse Probst; C Mistl; Simone Danner; S Kauffmann; Will Spooren; Markus Tolnay; Graeme Bilbe; S Kafmann; P Caromi; Markus A Ruegg
Mouse models of alpha-synucleinopathy and Lewy pathology.
Experimental gerontology 2000;35(9-10):1389-403.
2000: Herman van der Putten; Karl-Heinz Wiederhold; Alphonse Probst; Samuel Barbieri; C Mistl; Simone Danner; S Kauffmann; Katja Hofele; Will Spooren; Markus A Ruegg; S Lin; Pico Caroni; Bernd Sommer; Markus Tolnay; Graeme Bilbe
Neuropathology in mice expressing human alpha-synuclein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(16):6021-9.