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Janet Darbyshire

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Disorders

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HIV-1

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Sheena McCormack; Gita Ramjee; Anatoli Kamali; Helen Rees; Angela M Crook; Mitzy Gafos; Ute Jentsch; Robert Pool; Maureen Chisembele; Saidi Kapiga; Richard Mutemwa; Andrew Vallely; Thesla Palanee; Yuki Sookrajh; Charles J Lacey; Janet Darbyshire; Heiner Grosskurth; Albert Profy; Andrew Nunn; Richard Hayes; Jonathan Weber
PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial.
Paula Munderi; A Sarah Walker; C Kityo; Abdel G Babiker; Francis Ssali; A Reid; Janet Darbyshire; Heiner Grosskurth; Peter Mugyenyi; Diana M Gibb; Charles F Gilks
Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts.
A Sarah Walker; D Ford; Charles F Gilks; Paula Munderi; F Ssali; A Reid; E Katabira; Heiner Grosskurth; P Mugyenyi; James Hakim; Janet Darbyshire; Diana M Gibb; Abdel G Babiker
Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort.

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All Publications

2010: Sheena McCormack; Gita Ramjee; Anatoli Kamali; Helen Rees; Angela M Crook; Mitzy Gafos; Ute Jentsch; Robert Pool; Maureen Chisembele; Saidi Kapiga; Richard Mutemwa; Andrew Vallely; Thesla Palanee; Yuki Sookrajh; Charles J Lacey; Janet Darbyshire; Heiner Grosskurth; Albert Profy; Andrew Nunn; Richard Hayes; Jonathan Weber
PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial.
Lancet 2010;376(9749):1329-37.
2010: Paula Munderi; A Sarah Walker; C Kityo; Abdel G Babiker; Francis Ssali; A Reid; Janet Darbyshire; Heiner Grosskurth; Peter Mugyenyi; Diana M Gibb; Charles F Gilks
Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts.
HIV medicine 2010;11(5):334-44.
2010: A Sarah Walker; D Ford; Charles F Gilks; Paula Munderi; F Ssali; A Reid; E Katabira; Heiner Grosskurth; P Mugyenyi; James Hakim; Janet Darbyshire; Diana M Gibb; Abdel G Babiker
Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort.
Lancet 2010;375(9722):1278-86.
2009: Sheena McCormack; Douglas Taylor; Barbra Richardson; Janet Darbyshire; Quentin Sattentau; Quarraisha Abdool Karim; Salim S Abdool Karim; Ayesha Kharsany; Charles Lacey; Andrew Nunn; Jonathan Weber
Re: "Enhancement of HIV infection by cellulose sulfate," by Tao et al.
AIDS research and human retroviruses 2009;25(3):373; author reply 375-6.
2008: William Burman; Birgit Grund; Mollie P Roediger; Gerald Friedland; Janet Darbyshire; Albert W Wu
The impact of episodic CD4 cell count-guided antiretroviral therapy on quality of life.
Journal of acquired immune deficiency syndromes (1999) 2008;47(2):185-93.
2008: Wolfgang Stöhr; A Sarah Walker; Paula Munderi; Stefano Tugume; Charles F Gilks; Janet Darbyshire; James Hakim
Estimating glomerular filtration rate in HIV-infected adults in Africa: comparison of Cockcroft-Gault and Modification of Diet in Renal Disease formulae.
Antiviral therapy 2008;13(6):761-70.
2007: David Asboe; Ian G Williams; Ruth L Goodall; Janet Darbyshire; Malcolm H Hooker; Abdel G Babiker
A virological benefit from an induction/maintenance strategy: the Forte trial.
Antiviral therapy 2007;12(1):47-54.
2006: Wafaa M El-Sadr; Jens D Lundgren; James D Neaton; Fred M Gordin; D Abrams; Roberto C Arduino; A Babiker; William Burman; Nathan Clumeck; C J Cohen; D Cohn; D Cooper; Janet Darbyshire; Sean Emery; G Fätkenheuer; B Gazzard; B Grund; J Hoy; K Klingman; Marcelo H Losso; Norman Markowitz; J Neuhaus; A Phillips; C Rappoport
CD4+ count-guided interruption of antiretroviral treatment.
The New England journal of medicine 2006;355(22):2283-96.
2006: Patrick Yeni; David A Cooper; Jean-Pierre Aboulker; A G Babiker; D Carey; Janet Darbyshire; Marco Floridia; P M Girard; Ruth L Goodall; Malcolm H Hooker; A Mijch; Vincent Meiffredy; B Salzberger
Virological and immunological outcomes at 3 years after starting antiretroviral therapy with regimens containing non-nucleoside reverse transcriptase inhibitor, protease inhibitor, or both in INITIO: open-label randomised trial.
Lancet 2006;368(9532):287-98.
2006: Robert Newton; Lucy Carpenter; Delphine Casabonne; Valerie Beral; Abdel G Babiker; Janet Darbyshire; I V D Weller; Robin Weiss; A Kwan; Dimitra Bourboulia; F Munoz; Dimitrios Lagos; Chris Boshoff
A prospective study of Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus in adults with human immunodeficiency virus-1.
British journal of cancer 2006;94(10):1504-9.
2006: Francis Ssali; Wolfgang Stöhr; Paula Munderi; Andrew Reid; A Sarah Walker; Diana M Gibb; Peter Mugyenyi; Cissy Kityo; Heiner Grosskurth; James Hakim; Helen Byakwaga; Elly Katabira; Janet Darbyshire; Charles F Gilks
Prevalence, incidence and predictors of severe anaemia with zidovudine-containing regimens in African adults with HIV infection within the DART trial.
Antiviral therapy 2006;11(6):741-9.
2005: Jonathan Weber; Kamal Desai; Janet Darbyshire
The development of vaginal microbicides for the prevention of HIV transmission.
PLoS medicine 2005;2(5):e142.
2005: David T Dunn; Hannah Green; Clive Loveday; A Rinehart; Deenan Pillay; M Fisher; Sheena McCormack; Abdel G Babiker; Janet Darbyshire
A randomized controlled trial of the value of phenotypic testing in addition to genotypic testing for HIV drug resistance: evaluation of resistance assays (ERA) trial investigators.
Journal of acquired immune deficiency syndromes (1999) 2005;38(5):553-9.
2005: nick maskell; Christopher W H Davies; Andrew J Nunn; Emma Hedley; Fergus V Gleeson; Robert Miller; Rhian Gabe; Glyn L Rees; T E A Peto; Mark A Woodhead; Donald J Lane; Janet Darbyshire; Robert J O Davies
U.K. Controlled trial of intrapleural streptokinase for pleural infection.
The New England journal of medicine 2005;352(9):865-74.
2005: Felicity Clemens; Diana Elbourne; Janet Darbyshire; Stuart Pocock
Data monitoring in randomized controlled trials: surveys of recent practice and policies.
Clinical trials (London, England) 2005;2(1):22-33.
2004: David T Dunn; Diana M Gibb; Abdel G Babiker; Hannah Green; Janet Darbyshire; I V D Weller
HIV drug resistance testing: is the evidence really there?
Antiviral therapy 2004;9(5):641-8.
2004: Jean-Pierre Aboulker; Abdel G Babiker; Marie-Laure Chaix; Alexandra Compagnucci; Janet Darbyshire; M Debré; Albert Faye; Carlo Giaquinto; Diana M Gibb; Lynda Harper; Yacine Saïdi; A Sarah Walker
Highly active antiretroviral therapy started in infants under 3 months of age: 72-week follow-up for CD4 cell count, viral load and drug resistance outcome.
AIDS (London, England) 2004;18(2):237-45.
2003: Giota Touloumi; A G Babiker; Mike Kenward; Stuart J Pocock; Janet Darbyshire
A comparison of two methods for the estimation of precision with incomplete longitudinal data, jointly modelled with a time-to-event outcome.
Statistics in medicine 2003;22(20):3161-75.
2003: Kholoud Porter; Abdel Babiker; Krishnan Bhaskaran; Janet Darbyshire; Patrizio Pezzotti; Kholoud Porter; A Sarah Walker
Determinants of survival following HIV-1 seroconversion after the introduction of HAART.
Lancet 2003;362(9392):1267-74.
2003: Janet Darbyshire
Clinical trials of antiretroviral drugs: the role of the MRC AIDS Therapeutic Trials Committee (ATTC) and the MRC Clinical Trials Unit (CTU).
British journal of clinical pharmacology 2003;55(5):469-72.
2003: Abdel G Babiker; Janet Darbyshire; Patrizio Pezzotti; Kholoud Porter; Maria Prins; Caroline Sabin; A Sarah Walker
Short-term CD4 cell response after highly active antiretroviral therapy initiated at different times from seroconversion in 1,500 seroconverters.
Journal of acquired immune deficiency syndromes (1999) 2003;32(3):303-10.
2002: Miriam Rabkin; Wafaa M El-Sadr; David A Katzenstein; Joia Mukherjee; Henry Masur; Peter Mugyenyi; Paula Munderi; Janet Darbyshire
Antiretroviral treatment in resource-poor settings: clinical research priorities.
Lancet 2002;360(9344):1503-5.
2002: Alwyn Mwinga; Andrew Nunn; Bagrey Ngwira; Chifumbe Chintu; David K Warndorff; Paul Fine; Janet Darbyshire; Alimuddin Zumla
Mycobacterium vaccae (SRL172) immunotherapy as an adjunct to standard antituberculosis treatment in HIV-infected adults with pulmonary tuberculosis: a randomised placebo-controlled trial.
Lancet 2002;360(9339):1050-5.
2002: Giota Touloumi; Stuart J Pocock; Abdel G Babiker; Janet Darbyshire
Impact of missing data due to selective dropouts in cohort studies and clinical trials.
Epidemiology (Cambridge, Mass.) 2002;13(3):347-55.
2002: David Dunn; Abdel Babiker; Malcolm Hooker; Janet Darbyshire
The dangers of inferring treatment effects from observational data: a case study in HIV infection.
Controlled clinical trials 2002;23(2):106-10.
2001: Giota Touloumi; A G Babiker; Stuart J Pocock; Janet Darbyshire
Impact of missing data due to drop-outs on estimators for rates of change in longitudinal studies: a simulation study.
Statistics in medicine 2001;20(24):3715-28.
2001: A G Babiker; T E A Peto; K Porter; A Sarah Walker; Janet Darbyshire
Age as a determinant of survival in HIV infection.
Journal of clinical epidemiology 2001;54 Suppl 1():S16-21.
2001: Jonathan Weber; Andrew J Nunn; T O'Connor; D Jeffries; Valerie S Kitchen; Sheena McCormack; J Stott; Neil Almond; A Stone; Janet Darbyshire
'Chemical condoms' for the prevention of HIV infection: evaluation of novel agents against SHIV(89.6PD) in vitro and in vivo.
AIDS (London, England) 2001;15(12):1563-8.
2001: Angela Rose; JM Watson; C Graham; A J Nunn; F Drobniewski; L Peter Ormerod; Janet Darbyshire; J Leese
Tuberculosis at the end of the 20th century in England and Wales: results of a national survey in 1998.
Thorax 2001;56(3):173-9.
2000: A Sarah Walker; A G Babiker; Janet Darbyshire
Analysis of multivariate failure-time data from HIV clinical trials.
Controlled clinical trials 2000;21(2):75-93.
2000: Sheena McCormack; A Tilzey; A Carmichael; F Gotch; J Kepple; A Newberry; G Jones; S Lister; Simon Beddows; R Cheingsong; A Rees; Abdel G Babiker; J Banatvala; Claudine Bruck; Janet Darbyshire; D Tyrrell; C Van Hoecke; Jonathan Weber
A phase I trial in HIV negative healthy volunteers evaluating the effect of potent adjuvants on immunogenicity of a recombinant gp120W61D derived from dual tropic R5X4 HIV-1ACH320.
Vaccine 2000;18(13):1166-77.
2000: Janet Darbyshire; M Foulkes; R Peto; W Duncan; Abdel Babiker; R Collins; M Hughes; T Peto; A Walker
Immediate versus deferred zidovudine (AZT) in asymptomatic or mildly symptomatic HIV infected adults.
Cochrane database of systematic reviews (Online) 2000;(3):CD002039.
2000: Janet Darbyshire; M Foulkes; R Peto; W Duncan; Abdel Babiker; R Collins; M Hughes; T Peto; A Walker
Zidovudine (AZT) versus AZT plus didanosine (ddI) versus AZT plus zalcitabine (ddC) in HIV infected adults.
Cochrane database of systematic reviews (Online) 2000;(3):CD002038.
2000: Janet Darbyshire; M Foulkes; R Peto; W Duncan; Abdel Babiker; R Collins; M Hughes; T Peto; A Walker
Immediate versus deferred zidovudine (AZT) in asymptomatic or mildly symptomatic HIV infected adults.
Cochrane database of systematic reviews (Online) 2000;(2):CD002039.
2000: Janet Darbyshire; M Foulkes; R Peto; W Duncan; Abdel Babiker; R Collins; M Hughes; T Peto; A Walker
Zidovudine (AZT) versus AZT plus didanosine (ddI) versus AZT plus zalcitabine (ddC) in HIV infected adults.
Cochrane database of systematic reviews (Online) 2000;(2):CD002038.
1999: Janet Darbyshire
Confirmatory trials--a new approach?
Controlled clinical trials 1999;20(6):567-8.
1999: Ian R White; Abdel G Babiker; S Walker; Janet Darbyshire
Randomization-based methods for correcting for treatment changes: examples from the Concorde trial.
Statistics in medicine 1999;18(19):2617-34.
1999: Giota Touloumi; Stuart J Pocock; Abdel G Babiker; Janet Darbyshire
Estimation and comparison of rates of change in longitudinal studies with informative drop-outs.
Statistics in medicine 1999;18(10):1215-33.
1998: A Sarah Walker; T E A Peto; A G Babiker; Janet Darbyshire
Markers of HIV infection in the Concorde trial. Concorde Co-ordinating Committee.
QJM : monthly journal of the Association of Physicians 1998;91(6):423-38.
1998: Richard S Tedder; Steve Kaye; Clive Loveday; I V D Weller; D Jeffries; J Norman; J Weber; M Bourelly; R Foxall; Abdel G Babiker; Janet Darbyshire
Comparison of culture- and non-culture-based methods for quantification of viral load and resistance to antiretroviral drugs in patients given zidovudine monotherapy.
Journal of clinical microbiology 1998;36(4):1056-63.
1998: L Peter Ormerod; A Charlett; C Gilham; Janet Darbyshire; JM Watson
Geographical distribution of tuberculosis notifications in national surveys of England and Wales in 1988 and 1993: report of the Public Health Laboratory Service/British Thoracic Society/Department of Health Collaborative Group.
Thorax 1998;53(3):176-81.
1997: D Kumar; JM Watson; A Charlett; S Nicholas; Janet Darbyshire
Tuberculosis in England and Wales in 1993: results of a national survey. Public Health Laboratory Service/British Thoracic Society/Department of Health Collaborative Group.
Thorax 1997;52(12):1060-7.
1997: P Aaby; A Babiker; Janet Darbyshire; A Nunn; S Barreto; P Alonso; R Badaro; F Barros; Cesar Victora; F Binka; Benon Biryahwaho; C Byabamazima; S D K Sempala; B Tugume; P Kalebu; Jane F Kengeya-Kayondo; Jimmy Whitworth; L Paxton; J Convit; Tumani Corrah; K McAdam; M Datta; Y Dowlati; P Fine; M Tanner
Ethics of HIV trials.
Lancet 1997;350(9090):1546.
1997: I R White; S Walker; Abdel G Babiker; Janet Darbyshire
Impact of treatment changes on the interpretation of the Concorde trial.
AIDS (London, England) 1997;11(8):999-1006.
1997: R Peto; R Collins; D Sackett; Janet Darbyshire; A Babiker; Marc Buyse; H Stewart; Michael Baum; A Goldhirsch; G Bonadonna; P Valagussa; L Rutqvist; Diana Elbourne; C Davies; Otilia Dalesio; M Parmar; C Hill; Mike Clarke; Richard Gray; R Doll
The trials of Dr. Bernard Fisher: a European perspective on an American episode.
Controlled clinical trials 1997;18(1):1-13.
1995: Janet Darbyshire
Perspectives in drug therapy of HIV infection.
Drugs 1995;49 Suppl 1():1-3; discussion 38-40.
1991: Janet Darbyshire; David Schoenfeld; I V Weller
Clinical trials in HIV infection: current problems and future directions.
AIDS (London, England) 1991;5 Suppl 2():S167-73.