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Raphael Darcy

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Aoife M O'Mahony; Aoife Quinlan; Julien Ogier; John F Cryan; Raphael Darcy; Stephane Desgranges; Marc Devocelle; Caitriona M O'Driscoll
In vitro investigations of the efficacy of cyclodextrin-siRNA complexes modified with lipid-PEG-Octaarginine: towards a formulation strategy for non-viral neuronal siRNA delivery.
Valentina Villari; Caitriona M O'Driscoll; Raphael Darcy; Antonino Mazzaglia; Norberto Micali
Nanostructures of cationic amphiphilic cyclodextrin complexes with DNA.
Bruno M D C Godinho; Caitriona M O'Driscoll; Julien R Ogier; Raphael Darcy; John F Cryan
Self-assembling modified β-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease.

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All Publications

2013: Aoife M O'Mahony; Aoife Quinlan; Julien Ogier; John F Cryan; Raphael Darcy; Stephane Desgranges; Marc Devocelle; Caitriona M O'Driscoll
In vitro investigations of the efficacy of cyclodextrin-siRNA complexes modified with lipid-PEG-Octaarginine: towards a formulation strategy for non-viral neuronal siRNA delivery.
Pharmaceutical research 2013;30(4):1086-98.
2013: Valentina Villari; Caitriona M O'Driscoll; Raphael Darcy; Antonino Mazzaglia; Norberto Micali
Nanostructures of cationic amphiphilic cyclodextrin complexes with DNA.
Biomacromolecules 2013;14(3):811-7.
2013: Bruno M D C Godinho; Caitriona M O'Driscoll; Julien R Ogier; Raphael Darcy; John F Cryan
Self-assembling modified β-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease.
Molecular pharmaceutics 2013;10(2):640-9.
2012: A M O'Mahony; J F Cryan; Raphael Darcy; D Doyle; Caitriona M O'Driscoll
Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: effect of reversing primary and secondary face modifications.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;47(5):896-903.
2012: Jianfeng Guo; Julien R Ogier; Raphael Darcy; Stephane Desgranges; Caitriona O'Driscoll
Anisamide-targeted cyclodextrin nanoparticles for siRNA delivery to prostate tumours in mice.
Biomaterials 2012;33(31):7775-84.
2012: Anthony McMahon; Martin J O'Neill; Raphael Darcy; Ruth Donohue; Damien Forde; Eva Gomez; Caitriona M O'Driscoll
Targeted gene delivery to hepatocytes with galactosylated amphiphilic cyclodextrins.
The Journal of pharmacy and pharmacology 2012;64(8):1063-73.
2012: Aoife M O'Mahony; Julien Ogier; John F Cryan; Raphael Darcy; Stephane Desgranges; Caitriona M O'Driscoll
A click chemistry route to 2-functionalised PEGylated and cationic β-cyclodextrins: co-formulation opportunities for siRNA delivery.
Organic & biomolecular chemistry 2012;10(25):4954-60.
2011: Martin J O' Neill; Jianfeng Guo; Colin Byrne; Raphael Darcy; Caitriona M O' Driscoll
Mechanistic studies on the uptake and intracellular trafficking of novel cyclodextrin transfection complexes by intestinal epithelial cells.
International journal of pharmaceutics 2011;413(1-2):174-83.
2010: Jianfeng Guo; Karen A Fisher; Raphael Darcy; John F Cryan; Caitriona M O'Driscoll
Therapeutic targeting in the silent era: advances in non-viral siRNA delivery.
Molecular bioSystems 2010;6(7):1143-61.
2009: Colin Byrne; Florence Sallas; Dilip K Rai; Julien Ogier; Raphael Darcy
Poly-6-cationic amphiphilic cyclodextrins designed for gene delivery.
Organic & biomolecular chemistry 2009;7(18):3763-71.
2007: Simone McNicholas; Anna Rencurosi; Luigi Lay; Antonino Mazzaglia; Luisa Sturiale; Marta Perez; Raphael Darcy
Amphiphilic N-glycosyl-thiocarbamoyl cyclodextrins: synthesis, self-assembly, and fluorimetry of recognition by Lens culinaris lectin.
Biomacromolecules 2007;8(6):1851-7.
2006: M Walsh; Mark Tangney; M J O'Neill; John O Larkin; Declan M Soden; Sharon L McKenna; Raphael Darcy; Gerald C O'Sullivan; Caitriona M O'Driscoll
Evaluation of cellular uptake and gene transfer efficiency of pegylated poly-L-lysine compacted DNA: implications for cancer gene therapy.
Molecular pharmaceutics 2006;3(6):644-53.
2005: Patrick Falvey; Choon Woo Lim; Raphael Darcy; Tobias Revermann; Uwe Karst; Marcel Giesbers; Antonius T M Marcelis; behzad masihipour; Anthony W Coleman; David N Reinhoudt; Bart Jan Ravoo
Bilayer vesicles of amphiphilic cyclodextrins: host membranes that recognize guest molecules.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(4):1171-80.
2004: Antonino Mazzaglia; Damien Forde; Domenico Garozzo; Paola Malvagna; Bart Jan Ravoo; Raphael Darcy
Multivalent binding of galactosylated cyclodextrin vesicles to lectin.
Organic & biomolecular chemistry 2004;2(7):957-60.
2004: Sally-Ann Cryan; Ann Holohan; Ruth Donohue; Raphael Darcy; Caitriona M O'Driscoll
Cell transfection with polycationic cyclodextrin vectors.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(5):625-33.
2004: Domenico Lombardo; Alessandro Longo; Raphael Darcy; Antonino Mazzaglia
Structural properties of nonionic cyclodextrin colloids in water.
Langmuir : the ACS journal of surfaces and colloids 2004;20(4):1057-64.
2003: Antonino Mazzaglia; Nicola Angelini; Raphael Darcy; Ruth Donohue; Domenico Lombardo; Norberto Micali; Maria Teresa Sciortino; Valentina Villari; Luigi Monsù Scolaro
Novel heterotopic colloids of anionic porphyrins entangled in cationic amphiphilic cyclodextrins: spectroscopic investigation and intracellular delivery.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(23):5762-9.
2002: Ruth Donohue; Antonino Mazzaglia; Bart Jan Ravoo; Raphael Darcy
Cationic beta-cyclodextrin bilayer vesicles.
Chemical communications (Cambridge, England) 2002;(23):2864-5.
1997: F O'Keeffe; Shahab A Shamsi; Raphael Darcy; P Schwinté; I M Warner
A persubstituted cationic beta-cyclodextrin for chiral separations.
Analytical chemistry 1997;69(23):4773-82.