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Jeanine D'Armiento

Research Profile

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Elaine Wan; Sergey Zakharov; Xiao-Wei Nui; Takayuki Shiomi; Marc Waase; Neelesh Chudasama; Jeanine D'Armiento; Darshan Doshi; Shunichi Homma; Shinichi Iwata; Alexander Katchman; Christopher Kelly; Jared S Kushner; Guoxia Liu; Steven O Marx
Reduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice.
Monica P Goldklang; Sarah M Marks; Jeanine D'Armiento
Second hand smoke and COPD: lessons from animal studies.
Jeanine D'Armiento; John E Connett; Patrick Geraghty; Andrew J Ghio; Monica P Goldklang; Andrew A Hardigan; Monirul Islam; Michael D Roth; Steven M Scharf; Frank C Sciurba; Jincy Thankachen; Robert Wise; Robert F Foronjy
Increased matrix metalloproteinase (MMPs) levels do not predict disease severity or progression in emphysema.

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2013: Elaine Wan; Sergey Zakharov; Xiao-Wei Nui; Takayuki Shiomi; Marc Waase; Neelesh Chudasama; Jeanine D'Armiento; Darshan Doshi; Shunichi Homma; Shinichi Iwata; Alexander Katchman; Christopher Kelly; Jared S Kushner; Guoxia Liu; Steven O Marx
Reduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(5):1859-67.
2013: Monica P Goldklang; Sarah M Marks; Jeanine D'Armiento
Second hand smoke and COPD: lessons from animal studies.
Frontiers in physiology 2013;4():30.
2013: Jeanine D'Armiento; John E Connett; Patrick Geraghty; Andrew J Ghio; Monica P Goldklang; Andrew A Hardigan; Monirul Islam; Michael D Roth; Steven M Scharf; Frank C Sciurba; Jincy Thankachen; Robert Wise; Robert F Foronjy
Increased matrix metalloproteinase (MMPs) levels do not predict disease severity or progression in emphysema.
PloS one 2013;8(2):e56352.
2012: Monica Goldklang; Polina Golovatch; Vincent Lemaître; Daniel Rabinowitz; Jordis Trischler; Tina Zelonina; Jeanine D'Armiento
Activation of the TLR4 signaling pathway and abnormal cholesterol efflux lead to emphysema in ApoE-deficient mice.
American journal of physiology. Lung cellular and molecular physiology 2012;302(11):L1200-8.
2012: Alison M Wallace; Leo Arellanos; Jeanine D'Armiento; Adam Gaffney; Patrick Geraghty; Andrew Hardigan; Shaneeza Salim; Jincy Thankachen; Robert F Foronjy
Protein phosphatase 2A regulates innate immune and proteolytic responses to cigarette smoke exposure in the lung.
Toxicological sciences : an official journal of the Society of Toxicology 2012;126(2):589-99.
2012: Alison M Wallace; Domenico Accili; Robert F Foronjy; Jianqing He; Becky A Mercer; Peter D Paré; Andrew J Sandford; Jeanine D'Armiento
Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study.
Respiratory research 2012;13():79.
2012: Daniel C Andersson; Matthew J Betzenhauser; Jeanine D'Armiento; Albano C Meli; Steven Reiken; Takayuki Shiomi; Alisa Umanskaya; Andrew R Marks
Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.
Skeletal muscle 2012;2(1):9.
2012: Joseph George; Jie Sun; Jeanine D'Armiento
Transgenic expression of human matrix metalloproteinase-1 attenuates pulmonary arterial hypertension in mice.
Clinical science (London, England : 1979) 2012;122(2):83-92.
2011: Asahiro Morishita; Yasushi Suzuki; Joji Tani; Seishiro Watanabe; Hirohito Yoneyama; Hirohito Yoshida; Hisaaki Miyoshi; Hirohito Mori; Jeanine D'Armiento; Akihiro Deguchi; Kazushi Deguchi; Jian Gong; Reiji Haba; Takashi Himoto; Hisaaki Iwama; Kunihiko Izuishi; Kiyohito Kato; Kazutaka Kurokohchi; Yoshio Kushida; Tsutomu Masaki
Frequent loss of p19INK4D expression in hepatocellular carcinoma: relationship to tumor differentiation and patient survival.
Oncology reports 2011;26(6):1363-8.
2011: H Fukuda; C Hara-Miyauchi; Satsuki Mochizuki; M Nakayama; H Abe; Jeanine D'Armiento; H Okano; H J Okano; N Yamaguchi; Yasunori Okada
Host-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endostatin production.
British journal of cancer 2011;105(10):1615-24.
2011: Vincent Lemaître; Abdoulaye J Dabo; Jeanine D'Armiento
Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling.
Toxicological sciences : an official journal of the Society of Toxicology 2011;123(2):542-9.
2011: Patrick Geraghty; Abdoulaye J Dabo; Jeanine D'Armiento
TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease.
The Journal of biological chemistry 2011;286(34):30211-8.
2011: Joseph George; Jeanine D'Armiento
Transgenic expression of human matrix metalloproteinase-9 augments monocrotaline-induced pulmonary arterial hypertension in mice.
Journal of hypertension 2011;29(2):299-308.
2010: Anita I Sen; Takayuki Shiomi; Yasunori Okada; Jeanine D'Armiento
Deficiency of matrix metalloproteinase-13 increases inflammation after acute lung injury.
Experimental lung research 2010;36(10):615-24.
2010: Takayuki Shiomi; Vincent Lemaître; Jeanine D'Armiento; Yasunori Okada
Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases.
Pathology international 2010;60(7):477-96.
2010: Divya Mehra; David I Sternberg; Yuxia Jia; Stephen Canfield; Vincent Lemaitre; Takwi Nkyimbeng; Julie Wilder; Joshua R Sonett; Jeanine D'Armiento
Altered lymphocyte trafficking and diminished airway reactivity in transgenic mice expressing human MMP-9 in a mouse model of asthma.
American journal of physiology. Lung cellular and molecular physiology 2010;298(2):L189-96.
2010: Yusuke Sakamaki; Hiroyuki Sasamura; Kaori Hayashi; Kimiko Ishiguro; Hironari Takaishi; Yasunori Okada; Jeanine D'Armiento; Takao Saruta; Hiroshi Itoh
Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-induced albuminuria and glomerulosclerosis.
Nephron. Experimental nephrology 2010;115(2):e22-32.
2009: Polina Golovatch; Becky A Mercer; Vincent Lemaître; Alison Wallace; Robert F Foronjy; Jeanine D'Armiento
Role for cathepsin K in emphysema in smoke-exposed guinea pigs.
Experimental lung research 2009;35(8):631-45.
2009: Noriko Hattori; Satsuki Mochizuki; Kazuo Kishi; Tatsuo Nakajima; Hironari Takaishi; Jeanine D'Armiento; Yasunori Okada
MMP-13 plays a role in keratinocyte migration, angiogenesis, and contraction in mouse skin wound healing.
The American journal of pathology 2009;175(2):533-46.
2009: Vincent Lemaître; Henry E Kim; Margaret Forney-Prescott; Yasunori Okada; Jeanine D'Armiento
Transgenic expression of matrix metalloproteinase-9 modulates collagen deposition in a mouse model of atherosclerosis.
Atherosclerosis 2009;205(1):107-12.
2009: Jeanine D'Armiento; Steven M Scharf; Michael D Roth; John E Connett; Andrew Ghio; David Sternberg; Jonathan G Goldin; Thomas A Louis; Jenny T Mao; George T O'Connor; Joe W Ramsdell; Andrew L Ries; Neil W Schluger; Frank C Sciurba; Melissa A Skeans; Helen Voelker; Robert E Walter; Christine H Wendt; Gail G Weinmann; Robert Wise; Robert F Foronjy
Eosinophil and T cell markers predict functional decline in COPD patients.
Respiratory research 2009;10():113.
2008: David I Sternberg; Ram Gowda; Divya Mehra; Wu Qu; Alan Weinberg; William S Twaddell; Joydeep Sarkar; Allison Wallace; Barry I Hudson; Franco D'Ovidio; Selim M Arcasoy; Ravichandran Ramasamy; Jeanine D'Armiento; Ann Marie Schmidt; Joshua R Sonett
Blockade of receptor for advanced glycation end product attenuates pulmonary reperfusion injury in mice.
The Journal of thoracic and cardiovascular surgery 2008;136(6):1576-85.
2008: Robert F Foronjy; Jie Sun; Vincent Lemaitre; Jeanine D'Armiento
Transgenic expression of matrix metalloproteinase-1 inhibits myocardial fibrosis and prevents the transition to heart failure in a pressure overload mouse model.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(4):725-35.
2008: David I Sternberg; Daichi Shimbo; Steven M Kawut; Joydeep Sarkar; Georg Hurlitz; Franco D'Ovidio; David J Lederer; Jessie S Wilt; Selim M Arcasoy; David J Pinsky; Jeanine D'Armiento; Joshua R Sonett
Platelet activation in the postoperative period after lung transplantation.
The Journal of thoracic and cardiovascular surgery 2008;135(3):679-84.
2008: Hironari Takaishi; Tokuhiro Kimura; Seema Dalal; Yasunori Okada; Jeanine D'Armiento
Joint diseases and matrix metalloproteinases: a role for MMP-13.
Current pharmaceutical biotechnology 2008;9(1):47-54.
2008: Faruque Parvez; Yu Chen; Paul W Brandt-Rauf; Alfred Bernard; Xavier Dumont; Vesna Slavkovich; Maria Argos; Jeanine D'Armiento; Robert F Foronjy; M Rashidul Hasan; H E M Mahbubul Eunus; Joseph H Graziano; Habibul Ahsan
Nonmalignant respiratory effects of chronic arsenic exposure from drinking water among never-smokers in Bangladesh.
Environmental health perspectives 2008;116(2):190-5.
2008: Robert F Foronjy; Alison Wallace; Jeanine D'Armiento
The pharmokinetic limitations of antioxidant treatment for COPD.
Pulmonary pharmacology & therapeutics 2008;21(2):370-9.
2007: Carrie L Welch; Yu Sun; Brian J Arey; Vincent Lemaitre; Naresh Sharma; Minako Ishibashi; Scott Sayers; Rong Li; Anna Gorelik; Nick Pleskac; Kadesha Collins-Fletcher; Yoshiyuki Yasuda; Dieter Bromme; Jeanine D'Armiento; Martin Ogletree; Alan R Tall
Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- mice.
Circulation 2007;116(21):2444-52.
2007: Kazushi Imai; Seema S Dalal; John Hambor; Peter Mitchell; Yasunori Okada; William C Horton; Jeanine D'Armiento
Bone growth retardation in mouse embryos expressing human collagenase 1.
American journal of physiology. Cell physiology 2007;293(4):C1209-15.
2007: Naoto Kosaki; Hironari Takaishi; Satoru Kamekura; Tokuhiro Kimura; Yasunori Okada; Li Minqi; Norio Amizuka; Ung-il Chung; Kozo Nakamura; Hiroshi Kawaguchi; Yoshiaki Toyama; Jeanine D'Armiento
Impaired bone fracture healing in matrix metalloproteinase-13 deficient mice.
Biochemical and biophysical research communications 2007;354(4):846-51.
2007: Stefan Klotz; Alexander Hessel Jan Danser; Robert F Foronjy; Mehmet C Oz; Jie Wang; Donna Mancini; Jeanine D'Armiento; Daniel Burkhoff
The impact of angiotensin-converting enzyme inhibitor therapy on the extracellular collagen matrix during left ventricular assist device support in patients with end-stage heart failure.
Journal of the American College of Cardiology 2007;49(11):1166-74.
2007: Jeanine D'Armiento; Kazushi Imai; John F Schiltz; Natalya Kolesnekova; David I Sternberg; Kathleen F Benson; Annie Pardo; Moises Selman; Theresa Smolarek; Murty Vundavalli; Joshua Sonnet; Matthias Szabolcs; Kiran Chada
Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis.
Cancer research 2007;67(5):1902-9.
2006: Michael D Roth; John E Connett; Jeanine D'Armiento; Robert F Foronjy; Paul J Friedman; Jonathan G Goldin; Thomas A Louis; Jenny T Mao; Josephia R Muindi; George T O'Connor; Joe W Ramsdell; Andrew L Ries; Steven M Scharf; Neil W Schluger; Frank C Sciurba; Melissa A Skeans; Robert E Walter; Christine H Wendt; Robert Wise
Feasibility of retinoids for the treatment of emphysema study.
Chest 2006;130(5):1334-45.
2006: Yoko Osawa; Dingbang Xu; David I Sternberg; Joshua R Sonett; Jeanine D'Armiento; Reynold A Panettieri; Charles W Emala
Functional expression of the GABAB receptor in human airway smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 2006;291(5):L923-31.
2006: Becky Mercer; Constance Brinckerhoff; Jeanine D'Armiento
Activation of the MMP-1 promoter by cigarette smoke in human small airway epithelial cells requires ERK MAP kinase signaling: differential response of the 1G and 2G promoter sequences.
Proceedings of the American Thoracic Society 2006;3(6):477.
2006: Hiroshi Uchinami; Ekihiro Seki; David A Brenner; Jeanine D'Armiento
Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis.
Hepatology (Baltimore, Md.) 2006;44(2):420-9.
2006: Ayanna Augustus; Jonathan Buchanan; Tae-Sik Park; Kumiko Hirata; Hye-Lim Noh; Jie Sun; Shunichi Homma; Jeanine D'Armiento; E Dale Abel; Ira J Goldberg
Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction.
The Journal of biological chemistry 2006;281(13):8716-23.
2006: Robert F Foronjy; Oleg Mirochnitchenko; Olga Propokenko; Vincent Lemaitre; Yuxia Jia; Masayori Inouye; Yasunori Okada; Jeanine D'Armiento
Superoxide dismutase expression attenuates cigarette smoke- or elastase-generated emphysema in mice.
American journal of respiratory and critical care medicine 2006;173(6):623-31.
2006: Vincent Lemaître; Jeanine D'Armiento
Matrix metalloproteinases in development and disease.
Birth defects research. Part C, Embryo today : reviews 2006;78(1):1-10.
2006: Becky A Mercer; Jeanine D'Armiento
Emerging role of MAP kinase pathways as therapeutic targets in COPD.
International journal of chronic obstructive pulmonary disease 2006;1(2):137-50.
2005: Stefan Klotz; Robert F Foronjy; Marc L Dickstein; Anguo Gu; Ingrid M Garrelds; Alexander Hessel Jan Danser; Mehmet C Oz; Jeanine D'Armiento; Daniel Burkhoff
Mechanical unloading during left ventricular assist device support increases left ventricular collagen cross-linking and myocardial stiffness.
Circulation 2005;112(3):364-74.
2005: Robert F Foronjy; Becky A Mercer; Mark W Maxfield; Charles A Powell; Jeanine D'Armiento; Yasunori Okada
Structural emphysema does not correlate with lung compliance: lessons from the mouse smoking model.
Experimental lung research 2005;31(6):547-62.
2005: K Imai; Becky A Mercer; L L Schulman; Joshua R Sonett; Jeanine D'Armiento
Correlation of lung surface area to apoptosis and proliferation in human emphysema.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(2):250-8.
2004: Becky A Mercer; Natalia Kolesnikova; Joshua R Sonett; Jeanine D'Armiento
Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke.
The Journal of biological chemistry 2004;279(17):17690-6.
2003: Han Kim; Guo-Liang Xu; Alain C Borczuk; Steve Busch; Jorge Filmus; Mariana Capurro; Jerome S Brody; Jennifer Lange; Jeanine D'Armiento; Paul B Rothman; Charles A Powell
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.
American journal of respiratory cell and molecular biology 2003;29(6):694-701.
2003: Jeanine D'Armiento
Decreased elastin in vessel walls puts the pressure on.
The Journal of clinical investigation 2003;112(9):1308-10.
2003: Xander H T Wehrens; Stephan Lehnart; Fannie Huang; John A Vest; Steven Reiken; Peter J Mohler; Jie Sun; Silvia Guatimosim; Long-Sheng Song; Nora Rosemblit; Jeanine D'Armiento; Carlo Napolitano; Mirella Memmi; silvia priori; William Lederer; Andrew R Marks
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death.
Cell 2003;113(7):829-40.
2003: Robert F Foronjy; Yasunori Okada; Randolph Cole; Jeanine D'Armiento
Progressive adult-onset emphysema in transgenic mice expressing human MMP-1 in the lung.
American journal of physiology. Lung cellular and molecular physiology 2003;284(5):L727-37.
2003: Vincent Lemaître; Paul D Soloway; Jeanine D'Armiento
Increased medial degradation with pseudo-aneurysm formation in apolipoprotein E-knockout mice deficient in tissue inhibitor of metalloproteinases-1.
Circulation 2003;107(2):333-8.
2003: Steven Reiken; Marta Gaburjakova; Silvia Guatimosim; Ana Gomez; Jeanine D'Armiento; Daniel Burkhoff; Jie Wang; Guy Vassort; William Lederer; Andrew R Marks
Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol.
The Journal of biological chemistry 2003;278(1):444-53.
2003: Takayuki Shiomi; Yasunori Okada; Robert F Foronjy; John F Schiltz; Rudolph Jaenish; Steve Krane; Jeanine D'Armiento
Emphysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1.
Experimental lung research 2003;29(1):1-15.
2002: Jeanine D'Armiento
Matrix metalloproteinase disruption of the extracellular matrix and cardiac dysfunction.
Trends in cardiovascular medicine 2002;12(3):97-101.
2002: Kazushi Imai; Jeanine D'Armiento
Differential gene expression of sFRP-1 and apoptosis in pulmonary emphysema.
Chest 2002;121(3 Suppl):7S.
2002: Steven O Marx; Junko Kurokawa; Steven Reiken; Howard K Motoike; Jeanine D'Armiento; Andrew R Marks; Robert Kass
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel.
Science (New York, N.Y.) 2002;295(5554):496-9.
2001: Vincent Lemaître; T K O'Byrne; Alain C Borczuk; Yasunori Okada; Alan R Tall; Jeanine D'Armiento
ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis.
The Journal of clinical investigation 2001;107(10):1227-34.
2001: Kazushi Imai; Seema S Dalal; Elizabeth S Chen; R Downey; Larry L Schulman; Mark E Ginsburg; Jeanine D'Armiento
Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema.
American journal of respiratory and critical care medicine 2001;163(3 Pt 1):786-91.
2001: Robert F Foronjy; Jeanine D'Armiento
The role of collagenase in emphysema.
Respiratory research 2001;2(6):348-52.
2000: H E Kim; Seema S Dalal; E Young; MARIANNE LEGATO; Myron L Weisfeldt; Jeanine D'Armiento
Disruption of the myocardial extracellular matrix leads to cardiac dysfunction.
The Journal of clinical investigation 2000;106(7):857-66.
1999: Vincent Lemaître; T K O'Byrne; Seema S Dalal; Alan R Tall; Jeanine D'Armiento
Macrophage-specific expression of human collagenase (MMP-1) in transgenic mice.
Annals of the New York Academy of Sciences 1999;878():736-9.
1998: Xian-Cheng Jiang; Jeanine D'Armiento; R K Mallampalli; J Mar; Shi Fang Yan; M Lin
Expression of plasma phospholipid transfer protein mRNA in normal and emphysematous lungs and regulation by hypoxia.
The Journal of biological chemistry 1998;273(25):15714-8.
1997: Jeanine D'Armiento; Seema S Dalal; Kiran Chada
Tissue, temporal and inducible expression pattern of haptoglobin in mice.
Gene 1997;195(1):19-27.
1995: Jeanine D'Armiento; T DiColandrea; Seema S Dalal; Y Okada; M T Huang; A H Conney; Kiran Chada
Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis.
Molecular and cellular biology 1995;15(10):5732-9.
1992: Jeanine D'Armiento; Seema S Dalal; Y Okada; Richard Berg; Kiran Chada
Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema.
Cell 1992;71(6):955-61.