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Michael Dashwood

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Mats Dreifaldt; Andrzej Loesch; John R Muddle; Xu Shi-wen; Domingos Souza; Lennart Bodin; Audrey Dooley; Michael R Dashwood
The vasa vasorum and associated endothelial nitric oxide synthase is more important for saphenous vein than arterial bypass grafts.
Michael R Dashwood; Janice C Tsui
'No-touch' saphenous vein harvesting improves graft performance in patients undergoing coronary artery bypass surgery: a journey from bedside to bench.
Michael R Dashwood; Marilena Loizidou
Determination of cell-specific receptor binding using a combination of immunohistochemistry and in vitro autoradiography: relevance to therapeutic receptor targeting in cancer.

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2013: Mats Dreifaldt; Andrzej Loesch; John R Muddle; Xu Shi-wen; Domingos Souza; Lennart Bodin; Audrey Dooley; Michael R Dashwood
The vasa vasorum and associated endothelial nitric oxide synthase is more important for saphenous vein than arterial bypass grafts.
Angiology 2013;64(4):293-9.
2013: Michael R Dashwood; Janice C Tsui
'No-touch' saphenous vein harvesting improves graft performance in patients undergoing coronary artery bypass surgery: a journey from bedside to bench.
Vascular pharmacology 2013;58(3):240-50.
2012: Michael R Dashwood; Marilena Loizidou
Determination of cell-specific receptor binding using a combination of immunohistochemistry and in vitro autoradiography: relevance to therapeutic receptor targeting in cancer.
Methods in molecular biology (Clifton, N.J.) 2012;878():137-47.
2011: Michael R Dashwood; Ann Crump; Xu Shi-wen; Andrzej Loesch
Identification of neuronal nitric oxide synthase (nNOS) in human penis: a potential role of reduced neuronally-derived nitric oxide in erectile dysfunction.
Current pharmaceutical biotechnology 2011;12(9):1316-21.
2011: Michael R Dashwood; David Abraham
Endothelin: from bench to bedside and back.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;63(6):445-7.
2011: Michael R Dashwood; Audrey Dooley; Xu Shi-wen; David J Abraham; Mats Dreifaldt; Domingos S R Souza
Perivascular fat-derived leptin: a potential role in improved vein graft performance in coronary artery bypass surgery.
Interactive cardiovascular and thoracic surgery 2011;12(2):170-3.
2011: Mats Dreifaldt; Domingos S R Souza; Andrzej Loesch; John R Muddle; Mats G Karlsson; Derek Filbey; Lennart Bodin; Lars Norgren; Michael R Dashwood
The "no-touch" harvesting technique for vein grafts in coronary artery bypass surgery preserves an intact vasa vasorum.
The Journal of thoracic and cardiovascular surgery 2011;141(1):145-50.
2010: Mats Dreifaldt; Domingos S R Souza; Michael R Dashwood
Comparable patencies of the radial artery and right internal thoracic artery or saphenous vein beyond 5 years: results from the Radial Artery Patency and Clinical Outcomes trial.
The Journal of thoracic and cardiovascular surgery 2010;140(3):727-8; author reply 728-9.
2010: Michael R Dashwood; Stephen Fremes; Domingos S R Souza
Saphenous vein harvest with the Mayo extraluminal dissector: is endothelial function preserved?
The Journal of thoracic and cardiovascular surgery 2010;139(1):239-41; author reply 241.
2009: Michael R Dashwood; Kay Savage; Janice C S Tsui; Audrey Dooley; Sidney G Shaw; Maria S Fernández Alfonso; Lennart Bodin; Domingos S R Souza
Retaining perivascular tissue of human saphenous vein grafts protects against surgical and distension-induced damage and preserves endothelial nitric oxide synthase and nitric oxide synthase activity.
The Journal of thoracic and cardiovascular surgery 2009;138(2):334-40.
2009: Michael R Dashwood
Endothelin-1 and vein graft occlusion in patients undergoing bypass surgery.
European journal of clinical investigation 2009;39 Suppl 2():78-87.
2009: Andrzej Loesch; Michael R Dashwood
On the sympathetic innervation of the human greater saphenous vein: relevance to clinical practice.
Current vascular pharmacology 2009;7(1):58-67.
2009: Michael R Dashwood; Andrzej Loesch
The saphenous vein as a bypass conduit: the potential role of vascular nerves in graft performance.
Current vascular pharmacology 2009;7(1):47-57.
2009: Andrzej Loesch; Michael R Dashwood
Neural control of the vasculature: pharmacological targets in vascular disease.
Current vascular pharmacology 2009;7(1):1-2.
2008: Michael R Dashwood; Domingos S R Souza; Maria S Fernández-Alfonso
Re: Perivascular tissue of internal thoracic artery releases potent nitric oxide and prostacyclin-independent anticontractile factor.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2008;33(6):1161-2; author reply 1162-3.
2008: Janice C S Tsui; Daryll M Baker; Sidney G Shaw; Xu Shi-wen; Michael R Dashwood
Nitric oxide synthase in critically ischaemic muscle and alterations in isoform expression during revascularization surgery.
The British journal of surgery 2008;95(1):72-9.
2007: Janice C S Tsui; Daryll M Baker; Sidney G Shaw; Michael R Dashwood
Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion.
Angiology 2007;58(5):586-92.
2007: Xu Shi-wen; Elisabetta A Renzoni; Laura Kennedy; Sarah Howat; Yunliang Chen; Jeremy Pearson; George Bou-Gharios; Michael R Dashwood; Roland M Du Bois; Carol M Black; Christopher P Denton; David J Abraham; Andrew Leask
Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts.
Matrix biology : journal of the International Society for Matrix Biology 2007;26(8):625-32.
2007: Andrzej Loesch; Michael R Dashwood; María S Fernández-Alfonso
Improved saphenous vein graft patency for coronary artery bypass grafting: "no-touch" harvesting or "dissection without touching"?
The Journal of thoracic and cardiovascular surgery 2007;134(3):819-20; author reply 820-1.
2007: Moinuddin M Hoosein; Michael R Dashwood; Khaled Dawas; Haythem M M D A Ali; Katherine Grant; Felicity Savage; Irving Taylor; Marilena Loizidou
Altered endothelin receptor subtypes in colorectal cancer.
European journal of gastroenterology & hepatology 2007;19(9):775-82.
2007: Michael R Dashwood; Audrey Dooley; Xu Shi-wen; David J Abraham; Domingos S R Souza
Does periadventitial fat-derived nitric oxide play a role in improved saphenous vein graft patency in patients undergoing coronary artery bypass surgery?
Journal of vascular research 2007;44(3):175-81.
2007: Michael R Dashwood; Andrzej Loesch
Surgical damage of the saphenous vein and graft patency.
The Journal of thoracic and cardiovascular surgery 2007;133(1):274-5.
2006: Domingos S R Souza; Benny Johansson; Leif Bojö; Roland Karlsson; Håkan Geijer; Derek Filbey; Lennart Bodin; Mikael Arbeus; Michael R Dashwood
Harvesting the saphenous vein with surrounding tissue for CABG provides long-term graft patency comparable to the left internal thoracic artery: results of a randomized longitudinal trial.
The Journal of thoracic and cardiovascular surgery 2006;132(2):373-8.
2006: Xu Shi-wen; Fernando Rodríguez-Pascual; Santiago Lamas; holmes alan; Sarah Howat; Jeremy Pearson; Michael R Dashwood; Roland M Du Bois; Christopher P Denton; Carol M Black; David J Abraham; Andrew Leask
Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors.
Molecular and cellular biology 2006;26(14):5518-27.
2006: Michael R Dashwood; Janice C S Tsui
The effect of acute ischemia on ET-1 and its receptors in patients with underlying chronic ischemia of the lower limb.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):802-5.
2006: Andrzej Loesch; Michael R Dashwood; Domingos S R Souza
Does the method of harvesting the saphenous vein for coronary artery bypass surgery affect venous smooth muscle cells? iNOS immunolabelling and ultrastructural findings.
International journal of surgery (London, England) 2006;4(1):20-9.
2005: Janice C S Tsui; Michael R Dashwood
A role for endothelin-1 in peripheral vascular disease.
Current vascular pharmacology 2005;3(4):325-32.
2005: Jamie Y Jeremy; Nilima Shukla; Song Wan; Gavin Murphy; Gianni Angelini; Anthony Yim; Michael R Dashwood
The pathobiology of endothelin-1 in vein graft disease: are ETA receptor antagonists the solution to prevent vein graft failure?
Current vascular pharmacology 2005;3(4):315-23.
2005: Michael R Dashwood; Kay Savage; Audrey Dooley; Xu Shi-wen; David J Abraham; Domingos S R Souza
Effect of vein graft harvesting on endothelial nitric oxide synthase and nitric oxide production.
The Annals of thoracic surgery 2005;80(3):939-44.
2005: Andrzej Loesch; Barbara Gajkowska; Michael R Dashwood; Emerson T Fioretto; Karina Martinez Gagliardo; Ana R De Lima; A A C M Ribeiro
Endothelin-1 and endothelin receptors in the basilar artery of the capybara.
Journal of molecular histology 2005;36(1-2):25-34.
2004: Michael R Dashwood; Radhi Anand; Andrzej Loesch; Domingos Souza
Surgical trauma and vein graft failure: further evidence for a role of ET-1 in graft occlusion.
Journal of cardiovascular pharmacology 2004;44 Suppl 1():S16-9.
2004: Janice C S Tsui; Daryll M Baker; E Biecker; S Shaw; Michael R Dashwood
Altered endothelin-1 levels in acute lower limb ischemia and reperfusion.
Angiology 2004;55(5):533-9.
2004: Michael R Dashwood; Radhi Anand; Andrzej Loesch; Domingos S R Souza
Hypothesis: a potential role for the vasa vasorum in the maintenance of vein graft patency.
Angiology 2004;55(4):385-95.
2004: Xu Shi-wen; Yunliang Chen; Christopher P Denton; Mark Eastwood; Elisabetta A Renzoni; George Bou-Gharios; Jeremy Pearson; Michael R Dashwood; Roland M Du Bois; Carol M Black; Andrew Leask; David J Abraham
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.
Molecular biology of the cell 2004;15(6):2707-19.
2004: Shi-wen Xu; Sarah Howat; Elisabetta A Renzoni; holmes alan; Jeremy Pearson; Michael R Dashwood; George Bou-Gharios; Christopher P Denton; Roland M Du Bois; Carol M Black; Andrew Leask; David J Abraham
Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.
The Journal of biological chemistry 2004;279(22):23098-103.
2004: Song Wan; Anthony P C Yim; Jason L Johnson; Nilima Shukla; Gianni Angelini; F C T Smith; Michael R Dashwood; Jamie Y Jeremy
The endothelin 1A receptor antagonist BSF 302146 is a potent inhibitor of neointimal and medial thickening in porcine saphenous vein-carotid artery interposition grafts.
The Journal of thoracic and cardiovascular surgery 2004;127(5):1317-22.
2004: S R Ahmed; B L Johansson; M G Karlsson; Domingos S R Souza; Michael R Dashwood; Andrzej Loesch
Human saphenous vein and coronary bypass surgery: ultrastructural aspects of conventional and "no-touch" vein graft preparations.
Histology and histopathology 2004;19(2):421-33.
2003: Janice C S Tsui; Daryll M Baker; E Biecker; S Shaw; Michael R Dashwood
Evidence for the involvement of endothelin-1 but not urotensin-II in chronic lower limb ischaemia in man.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2003;25(5):443-50.
2003: Masood A Khan; Cecil S Thompson; Michael R Dashwood; Faiz H Mumtaz; Robert J Morgan; Dimitri P Mikhailidis
Endothelin-1 and nitric oxide in the pathogenesis of urinary tract disorders secondary to bladder outlet obstruction.
Current vascular pharmacology 2003;1(1):27-31.
2003: Joanne Marks; Edward S Debnam; Michael R Dashwood; Kaila Surjit Srai; Robert J Unwin
Detection of glucagon receptor mRNA in the rat proximal tubule: potential role for glucagon in the control of renal glucose transport.
Clinical science (London, England : 1979) 2003;104(3):253-8.
2003: Albert C M Ong; Linda J Newby; Michael R Dashwood
Expression and cellular localisation of renal endothelin-1 and endothelin receptor subtypes in autosomal-dominant polycystic kidney disease.
Nephron. Experimental nephrology 2003;93(2):e80.
2002: M E Sullivan; Faiz H Mumtaz; Michael R Dashwood; C S Thompson; Khalid M Naseem; K Richard Bruckdorfer; D P Mikhailidis; R J Morgan
Enhanced relaxation of diabetic rabbit cavernosal smooth muscle in response to nitric oxide: potential relevance to erectile dysfunction.
International journal of impotence research 2002;14(6):523-32.
2002: Michael R Dashwood; Janice C S Tsui
Endothelins and the 'French paradox': are detrimental effects of red wine also associated with an action on endothelin synthesis?
Angiology 2002;53(6):749-51.
2002: Robert C Calvert; Faiz H Mumtaz; Michael R Dashwood; Masood A Khan; Robert J Morgan; Dimitri P Mikhailidis; Cecil S Thompson
Reduction of endothelin-1 binding and inhibition of endothelin-1-mediated detrusor contraction by naftidrofuryl.
Clinical science (London, England : 1979) 2002;103 Suppl 48():459S-463S.
2002: Bruno M Balsiger; Andreas Rickenbacher; Penelope Jane Boden; Erwin Biecker; Janice C S Tsui; Michael R Dashwood; Jürg Reichen; Sidney G Shaw
Endothelin A-receptor blockade in experimental diabetes improves glucose balance and gastrointestinal function.
Clinical science (London, England : 1979) 2002;103 Suppl 48():430S-433S.
2002: Michael W Smith; K Bhasker Shenoy; Edward S Debnam; Michael R Dashwood; Linda J Churchill; Kaila Surjit Srai
Divalent metal inhibition of non-haem iron uptake across the rat duodenal brush border membrane.
The British journal of nutrition 2002;88(1):51-6.
2002: Janice C S Tsui; Daryll M Baker; E Biecker; S Shaw; Michael R Dashwood
Potential role of endothelin 1 in ischaemia-induced angiogenesis in critical leg ischaemia.
The British journal of surgery 2002;89(6):741-7.
2002: Domingos S R Souza; Michael R Dashwood; Janice C S Tsui; Derek Filbey; Lennart Bodin; Benny Johansson; Jan Borowiec
Improved patency in vein grafts harvested with surrounding tissue: results of a randomized study using three harvesting techniques.
The Annals of thoracic surgery 2002;73(4):1189-95.
2002: Janice C S Tsui; Michael R Dashwood
Recent strategies to reduce vein graft occlusion: a need to limit the effect of vascular damage.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2002;23(3):202-8.
2002: O Agu; George Hamilton; Daryll M Baker; Michael R Dashwood
Endothelin receptors in the aetiology and pathophysiology of varicose veins.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2002;23(2):165-71.
2002: Janice C S Tsui; Domingos S R Souza; Derek Filbey; Mats G Karlsson; Michael R Dashwood
Localization of nitric oxide synthase in saphenous vein grafts harvested with a novel "no-touch" technique: potential role of nitric oxide contribution to improved early graft patency rates.
Journal of vascular surgery 2002;35(2):356-62.
2002: Michael R Dashwood; Janice C S Tsui
Endothelin-1 and atherosclerosis: potential complications associated with endothelin-receptor blockade.
Atherosclerosis 2002;160(2):297-304.
2002: R Anand; Diane D Harry; Stephen Geoffrey Holt; Pam Milner; Michael R Dashwood; David W Goodier; Michael Jarmulowicz; K Moore
Endothelin is an important determinant of renal function in a rat model of acute liver and renal failure.
Gut 2002;50(1):111-7.
2001: Janice C S Tsui; Domingos S R Souza; Derek Filbey; V Bomfim; Michael R Dashwood
Preserved endothelial integrity and nitric oxide synthase in saphenous vein grafts harvested by a 'no-touch' technique.
The British journal of surgery 2001;88(9):1209-15.
2001: Domingos S R Souza; V Bomfim; H Skoglund; Michael R Dashwood; Jan Borowiec; Lennart Bodin; Derek Filbey
High early patency of saphenous vein graft for coronary artery bypass harvested with surrounding tissue.
The Annals of thoracic surgery 2001;71(3):797-800.
2001: Xu Shi-wen; Christopher P Denton; Michael R Dashwood; holmes alan; George Bou-Gharios; Jeremy Pearson; Carol M Black; David J Abraham
Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1.
The Journal of investigative dermatology 2001;116(3):417-25.
2001: Faiz H Mumtaz; Michael R Dashwood; C Thompson; M Khan; A Naylor; Dimitri P Mikhailidis; R Morgan
Autoradiographic localisation and contractile properties of prostatic endothelin receptors in patients with bladder outlet obstruction.
European urology 2001;39(1):48-56.
2000: C S Thompson; M A Khan; Michael R Dashwood; F H Mumtaz; Dimitri P Mikhailidis; R J Morgan
Altered cavernosal endothelin-B-receptor binding sites in the rabbit model of partial bladder outlet obstruction.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S260-1.
2000: Michael R Dashwood; I Anita Jagroop; D A Gorog; J P Bagger
A potential role for endothelin-1 in peripheral vascular disease.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S93-4.
2000: halgurd ali; Michael R Dashwood; Khaled Dawas; Marilena Loizidou; Felicity Savage; Irving Taylor
Endothelin receptor expression in colorectal cancer.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S69-71.
2000: halgurd ali; Marilena Loizidou; Michael R Dashwood; Felicity Savage; C Sheard; Irving Taylor
Stimulation of colorectal cancer cell line growth by ET-1 and its inhibition by ET(A) antagonists.
Gut 2000;47(5):685-8.
2000: Masood A Khan; Cecil S Thompson; Michael R Dashwood; Faiz H Mumtaz; Dimitri P Mikhailidis; Robert J Morgan
Doxazosin modifies serotonin-mediated rabbit urinary bladder contraction. Potential clinical relevance.
Urological research 2000;28(2):116-21.
2000: M W Smith; Edward S Debnam; Michael R Dashwood; Kaila Surjit Srai
Structural and cellular adaptation of duodenal iron uptake in rats maintained on an iron-deficient diet.
Pflügers Archiv : European journal of physiology 2000;439(4):449-54.
1999: MA Khan; Michael R Dashwood; Cecil S Thompson; Faiz H Mumtaz; Dimitri P Mikhailidis; Robert J Morgan
Up-regulation of endothelin (ET(A) and ET(B)) receptors and down-regulation of nitric oxide synthase in the detrusor of a rabbit model of partial bladder outlet obstruction.
Urological research 1999;27(6):445-53.
1999: M A Khan; Michael R Dashwood; C S Thompson; F H Mumtaz; Dimitri P Mikhailidis; R J Morgan
Time-dependent up-regulation of endothelin-A receptors and down-regulation of endothelin-B receptors and nitric oxide synthase binding sites in the renal medulla of a rabbit model of partial bladder outlet obstruction: potential clinical relevance.
BJU international 1999;84(9):1073-80.
1999: Masood A Khan; Michael R Dashwood; Cecil S Thompson; J Auld; R J Morgan; Dimitri P Mikhailidis
Down-regulation of endothelin-B receptor sites in cavernosal tissue of a rabbit model of partial bladder outlet obstruction: potential clinical relevance.
World journal of urology 1999;17(5):290-5.
1999: Masood A Khan; Michael R Dashwood; Cecil S Thompson; Faiz H Mumtaz; R J Morgan; Dimitri P Mikhailidis
Time-dependent up-regulation of neuronal 5-hydroxytryptamine binding sites in the detrusor of a rabbit model of partial bladder outlet obstruction.
World journal of urology 1999;17(5):255-60.
1999: Masood A Khan; Michael R Dashwood; Cecil S Thompson; Faiz H Mumtaz; Dimitri P Mikhailidis; Robert J Morgan
Up-regulation of endothelin-B (ETB) receptors and ETB receptor-mediated rabbit detrusor contraction in partial bladder outlet obstruction.
BJU international 1999;84(6):714-9.
1999: M E Sullivan; Cecil S Thompson; Michael R Dashwood; Masood A Khan; Jamie Y Jeremy; Robert J Morgan; Dimitri P Mikhailidis
Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular disease?
Cardiovascular research 1999;43(3):658-65.
1999: Michael R Dashwood; P Noertersheuser; Michael Kirchengast; Klaus Münter
Altered endothelin-1 binding following balloon angioplasty of pig coronary arteries: effect of the ETA receptor antagonist, LU 135252.
Cardiovascular research 1999;43(2):445-56.
1999: Faiz H Mumtaz; M E Sullivan; Cecil S Thompson; Michael R Dashwood; Khalid M Naseem; K Richard Bruckdorfer; Dimitri P Mikhailidis; Robert J Morgan
Alterations in the nitric oxide synthase binding sites and non-adrenergic, non-cholinergic mediated smooth muscle relaxation in the diabetic rabbit bladder outlet: possible relevance to the pathogenesis of diabetic cystopathy.
The Journal of urology 1999;162(2):558-66.
1999: Faiz H Mumtaz; Masood A Khan; M E Sullivan; Cecil S Thompson; Dimitri P Mikhailidis; Robert J Morgan; Michael R Dashwood
Potential role of endothelin and nitric oxide in physiology and pathophysiology of the lower urinary tract.
Endothelium : journal of endothelial cell research 1999;7(1):1-9.
1999: Masood A Khan; Michael R Dashwood; Faiz H Mumtaz; Cecil S Thompson; Dimitri P Mikhailidis; Robert J Morgan
Upregulation of endothelin A receptor sites in the rabbit diabetic kidney: potential relevance to the early pathogenesis of diabetic nephropathy.
Nephron 1999;83(3):261-7.
1999: Faiz H Mumtaz; Michael R Dashwood; Cecil S Thompson; M E Sullivan; Dimitri P Mikhailidis; Robert J Morgan
Increased expression of endothelin B receptors in the diabetic rabbit urinary bladder: functional relevance.
BJU international 1999;83(1):113-22.
1998: Jamie Y Jeremy; Michael R Dashwood; D Mehta; MOHAMMAD IZZAT; Nilima Shukla; Gianni Angelini
Nitric oxide, prostacyclin and cyclic nucleotide formation in externally stented porcine vein grafts.
Atherosclerosis 1998;141(2):297-305.
1998: Masood A Khan; Cecil S Thompson; M E Sullivan; Michael R Dashwood; Jamie Y Jeremy; R J Morgan; Dimitri P Mikhailidis
Endothelin and erectile dysfunction: a target for pharmacological intervention?
Expert opinion on investigational drugs 1998;7(11):1759-67.
1998: S Allen; Michael R Dashwood; K Morrison; M Yacoub
Differential leukotriene constrictor responses in human atherosclerotic coronary arteries.
Circulation 1998;97(24):2406-13.
1998: Michael R Dashwood; D Mehta; MOHAMMAD IZZAT; M Timm; A J Bryan; Gianni Angelini; Jamie Y Jeremy
Distribution of endothelin-1 (ET) receptors (ET(A) and ET(B)) and immunoreactive ET-1 in porcine saphenous vein-carotid artery interposition grafts.
Atherosclerosis 1998;137(2):233-42.
1998: Michael R Dashwood; M Timm; J R Muddle; Albert C M Ong; J R Tippins; R Parker; D McManus; AJ Murday; B P Madden; JUAN-CARLOS KASKI
Regional variations in endothelin-1 and its receptor subtypes in human coronary vasculature: pathophysiological implications in coronary disease.
Endothelium : journal of endothelial cell research 1998;6(1):61-70.
1998: Shi-wen Xu; Christopher P Denton; Michael R Dashwood; David J Abraham; Carol M Black
Endothelin-1 regulation of intercellular adhesion molecule-1 expression in normal and sclerodermal fibroblasts.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S545-7.
1998: S Xu; Christopher P Denton; holmes alan; Michael R Dashwood; David J Abraham; Carol M Black
Endothelins: effect on matrix biosynthesis and proliferation in normal and scleroderma fibroblasts.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S360-3.
1998: Michael R Dashwood; Jamie Y Jeremy; D Mehta; MOHAMMAD IZZAT; M Timm; A J Bryan; Gianni Angelini
Endothelin-1 and endothelin receptors in porcine saphenous vein-carotid artery grafts.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S328-30.
1998: M E Sullivan; Michael R Dashwood; Cecil S Thompson; Dimitri P Mikhailidis; R J Morgan
Down-regulation of endothelin-B receptor sites in cavernosal tissue of hypercholesterolaemic rabbits.
British journal of urology 1998;81(1):128-34.
1997: M E Sullivan; Michael R Dashwood; Cecil S Thompson; John R Muddle; Dimitri P Mikhailidis; R J Morgan
Alterations in endothelin B receptor sites in cavernosal tissue of diabetic rabbits: potential relevance to the pathogenesis of erectile dysfunction.
The Journal of urology 1997;158(5):1966-72.
1997: David J Abraham; R Vancheeswaran; Michael R Dashwood; Vineeth Rajkumar; P Pantelides; Shi-wen Xu; Roland M Du Bois; Carol M Black
Increased levels of endothelin-1 and differential endothelin type A and B receptor expression in scleroderma-associated fibrotic lung disease.
The American journal of pathology 1997;151(3):831-41.
1997: Michael R Dashwood; F H Mumtaz; M E Sullivan; I Anita Jagroop; C S Thompson; R J Morgan; D P Mikhailidis
The paracrine endothelin system: pathophysiology and implications in clinical medicine.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1997;35(8):645-6.
1997: Jamie Y Jeremy; Michael R Dashwood; M Timm; MOHAMMAD IZZAT; D Mehta; Alan J Bryan; Gianni Angelini
Nitric oxide synthase and adenylyl and guanylyl cyclase activity in porcine interposition vein grafts.
The Annals of thoracic surgery 1997;63(2):470-6.
1997: Michael R Dashwood; PK Thomas
Neurovascular [125I]-ET-1 binding sites on human peripheral nerve.
Endothelium : journal of endothelial cell research 1997;5(2):119-23.
1996: Peter Dahm; Mikael Bodelsson; K Törnebrandt; John R Muddle; R M Sykes; M Yacoub; Michael R Dashwood
Binding of [3H]-5-hydroxytryptamine to human coronary artery and bypass graft vessels.
Cardiovascular research 1996;31(5):800-6.
1996: M E Sullivan; C R Bell; M A Miller; Cecil S Thompson; Michael R Dashwood; J Y Jeremy; Dimitri P Mikhailidis; R J Morgan
Diabetes mellitus increases nitric oxide synthase in penises but not in major pelvic ganglia of rats.
British journal of urology 1996;77(2):329.
1996: Daniel S McQueen; U Eder; M Timm; H Winkler; Michael R Dashwood; Susan M Bond
Secretoneurin. A novel carotid body peptide.
Advances in experimental medicine and biology 1996;410():329-33.
1996: M E Sullivan; C R Bell; Michael R Dashwood; M A Miller; Cecil S Thompson; Dimitri P Mikhailidis; R J Morgan
Autoradiographic localization of nitric oxide synthase binding sites in normal and diabetic rat corpus cavernosum.
European urology 1996;30(4):506-11.
1996: J H St Lambert; Michael R Dashwood; K Michael Spyer
Role of brainstem adenosine A1 receptors in the cardiovascular response to hypothalamic defence area stimulation in the anaesthetized rat.
British journal of pharmacology 1996;117(2):277-82.
1995: C R Bell; M E Sullivan; Michael R Dashwood; John R Muddle; R J Morgan
The density and distribution of endothelin 1 and endothelin receptor subtypes in normal and diabetic rat corpus cavernosum.
British journal of urology 1995;76(2):203-7.
1995: Daniel S McQueen; Michael R Dashwood; V J Cobb; Susan M Bond; C G Marr; K Michael Spyer
Endothelins and rat carotid body: autoradiographic and functional pharmacological studies.
Journal of the autonomic nervous system 1995;53(2-3):115-25.
1995: T N Luu; Michael R Dashwood; Adrian H Chester; John R Muddle; M H Yacoub
Calcitonin gene-related peptide in healthy and atheromatous human epicardial coronary arteries. Function and receptor characterization.
Journal of vascular research 1995;32(2):93-9.
1995: M Timm; JUAN-CARLOS KASKI; Michael R Dashwood
Endothelin-like immunoreactivity in atherosclerotic human coronary arteries.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S442-4.
1995: Michael R Dashwood; M Timm; John R Muddle; D Shah; J R Tippins; JUAN-CARLOS KASKI
[3H]bosentan binding to human coronary artery: functional correlates.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S376-9.
1995: Michael R Dashwood; M Timm; JUAN-CARLOS KASKI
Regional variations in ETA/ETB binding sites in human coronary vasculature.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S351-4.
1994: Sean P Allen; Adrian H Chester; Michael R Dashwood; S Tadjkarimi; P J Piper; M H Yacoub
Preferential vasoconstriction to cysteinyl leukotrienes in the human saphenous vein compared with the internal mammary artery. Implications for graft performance.
Circulation 1994;90(1):515-24.
1994: R Vancheeswaran; A Azam; C Black; Michael R Dashwood
Localization of endothelin-1 and its binding sites in scleroderma skin.
The Journal of rheumatology 1994;21(7):1268-76.
1994: Michael R Dashwood; Sean P Allen; T N Luu; John R Muddle
The effect of the ETA receptor antagonist, FR 139317, on [125I]-ET-1 binding to the atherosclerotic human coronary artery.
British journal of pharmacology 1994;112(2):386-9.
1994: Daniel S McQueen; Michael R Dashwood; V J Cobb; C G Marr
Effects of endothelins on respiration and arterial chemoreceptor activity in anaesthetised rats.
Advances in experimental medicine and biology 1994;360():289-91.
1993: D C Crossman; Michael R Dashwood; Graham W Taylor; R Wellings; R W Fuller
Sodium cromoglycate: evidence of tachykinin antagonist activity in the human skin.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(1):167-72.
1993: T N Luu; Michael R Dashwood; Adrian H Chester; S Tadjkarimi; M H Yacoub
Action of vasoactive intestinal peptide and distribution of its binding sites in vessels used for coronary artery bypass grafts.
The American journal of cardiology 1993;71(15):1278-82.
1993: Sean P Allen; Michael R Dashwood; Adrian H Chester; S Tadjkarimi; M Collins; P J Piper; M H Yacoub
Influence of atherosclerosis on the vascular reactivity of isolated human epicardial coronary arteries to leukotriene C4.
Cardioscience 1993;4(1):47-54.
1993: Michael R Dashwood; Daniel S McQueen; R M Sykes; John R Muddle; M D Daly; Y Evrard; K Michael Spyer
The effects of almitrine on (3H)5HT and (125I) endothelin binding to central and peripheral receptors: an in vitro autoradiographic study in the cat.
Advances in experimental medicine and biology 1993;337():17-23.
1993: Michael R Dashwood; S G Barker; John R Muddle; M H Yacoub; J F Martin
[125I]-endothelin-1 binding to vasa vasorum and regions of neovascularization in human and porcine blood vessels: a possible role for endothelin in intimal hyperplasia and atherosclerosis.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S343-7.
1991: D C Crossman; S W Larkin; Michael R Dashwood; GJ Davies; M Yacoub; Attilio Maseri
Responses of atherosclerotic human coronary arteries in vivo to the endothelium-dependent vasodilator substance P.
Circulation 1991;84(5):2001-10.
1991: Michael R Dashwood; R M Sykes; M J Collins; S Prehar; S Theodoropoulos; M H Yacoub
Identification of [(125)I]endothelin binding sites in human coronary tissue.
Neurochemistry international 1991;18(4):439-44.
1991: Cecil S Thompson; R M Sykes; John R Muddle; Michael R Dashwood
Distribution of 125I-labelled insulin-binding sites in peripheral tissues of the normal and diabetic rat: an autoradiographic study.
The Journal of endocrinology 1991;128(1):85-9.
1991: Michael R Dashwood; R M Sykes; John R Muddle; M J Collins; S Prehar; S Theodoropoulos; M H Yacoub
Autoradiographic localization of [125I]endothelin binding sites in human blood vessels and coronary tissue: functional correlates.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S458-62.
1991: K Michael Spyer; Daniel S McQueen; Michael R Dashwood; R M Sykes; M B Daly; John R Muddle
Localization of [125I]endothelin binding sites in the region of the carotid bifurcation and brainstem of the cat: possible baro- and chemoreceptor involvement.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S385-9.
1990: S A Marks; R D Stein; Michael R Dashwood; Michael P Gilbey
[3H]prazosin binding in the intermediolateral cell column and the effects of iontophoresed methoxamine on sympathetic preganglionic neuronal activity in the anaesthetized cat and rat.
Brain research 1990;530(2):321-4.
1990: C J Moody; Michael R Dashwood; R M Sykes; M Chester; S M Jones; M H Yacoub; S E Harding
Functional and autoradiographic evidence for endothelin 1 receptors on human and rat cardiac myocytes. Comparison with single smooth muscle cells.
Circulation research 1990;67(3):764-9.
1990: D C Crossman; Michael R Dashwood; S D Brain; J McEwan; J D Pearson
Action of calcitonin gene-related peptide upon bovine vascular endothelial and smooth muscle cells grown in isolation and co-culture.
British journal of pharmacology 1990;99(1):71-6.
1990: Michael R Dashwood; R M Sykes; C S Thomson
Autoradiographic demonstration of [3H] loperamide binding to opioid receptors in rat and human small intestine.
Progress in clinical and biological research 1990;328():165-9.
1989: Adrian H Chester; Michael R Dashwood; J G Clarke; S W Larkin; GJ Davies; S Tadjkarimi; Attilio Maseri; M H Yacoub
Influence of endothelin on human coronary arteries and localization of its binding sites.
The American journal of cardiology 1989;63(18):1395-8.
1989: Michael R Dashwood; M Turner; M Jacobs
Endothelin-1: contractile responses and autoradiographic localization of receptors in rabbit blood vessels.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S183-5.
1988: Michael R Dashwood; John R Muddle; K Michael Spyer
Opiate receptor subtypes in the nucleus tractus solitarii of the cat: the effect of vagal section.
European journal of pharmacology 1988;155(1-2):85-92.
1986: Michael R Dashwood; R M Sykes; Cecil S Thompson
Autoradiographic localization of opioid receptor types in the rat small intestine.
NIDA research monograph 1986;75():315-8.
1985: Michael R Dashwood; Michael P Gilbey; K Michael Spyer
The localization of adrenoceptors and opiate receptors in regions of the cat central nervous system involved in cardiovascular control.
Neuroscience 1985;15(2):537-51.