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Alana Althage

Research Profile

Living Beings

Anatomy

Disorders

Chemicals & Drugs

Genes & Molecular Sequences

Major Histocompatibility Complex

Physiology

Cytotoxicity, Immunologic

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Publications

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John R Walker; James Watson; Gus Welzel; Tove tuntland; Hugo D Urbina; Alana Althage; Juliano Alves; Jennifer L Harris; Laura H Jacobson; Bo Liu; Daniel Mason; Weijia Ou; Reynand Pacoma; Eric C Peters; Andrew M Schumacher
Enhanced proteolytic clearance of plasma Aβ by peripherally administered neprilysin does not result in reduced levels of brain Aβ in mice.
Kristen Johnson; Shelly Meeusen; Joshua N Payette; Matthew S Tremblay; Jianing Wang; Xu Wu; Shoutian Zhu; Alana Althage; Laure C Bouchez; Charles Y Cho; Peter G Schultz
A stem cell-based approach to cartilage repair.
Ka Fai Suen; Mary S Turner; Feng Gao; Bo Liu; Alana Althage; Anthony Slavin; Weijia Ou; Elizabeth Zuo; Michael Eckart; Tomohisa Ogawa; Masao Yamada; Tove tuntland; Jennifer L Harris; John W Trauger
Transient expression of an IL-23R extracellular domain Fc fusion protein in CHO vs. HEK cells results in improved plasma exposure.

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All Publications

2013: John R Walker; James Watson; Gus Welzel; Tove tuntland; Hugo D Urbina; Alana Althage; Juliano Alves; Jennifer L Harris; Laura H Jacobson; Bo Liu; Daniel Mason; Weijia Ou; Reynand Pacoma; Eric C Peters; Andrew M Schumacher
Enhanced proteolytic clearance of plasma Aβ by peripherally administered neprilysin does not result in reduced levels of brain Aβ in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(6):2457-64.
2012: Kristen Johnson; Shelly Meeusen; Joshua N Payette; Matthew S Tremblay; Jianing Wang; Xu Wu; Shoutian Zhu; Alana Althage; Laure C Bouchez; Charles Y Cho; Peter G Schultz
A stem cell-based approach to cartilage repair.
Science (New York, N.Y.) 2012;336(6082):717-21.
2010: Ka Fai Suen; Mary S Turner; Feng Gao; Bo Liu; Alana Althage; Anthony Slavin; Weijia Ou; Elizabeth Zuo; Michael Eckart; Tomohisa Ogawa; Masao Yamada; Tove tuntland; Jennifer L Harris; John W Trauger
Transient expression of an IL-23R extracellular domain Fc fusion protein in CHO vs. HEK cells results in improved plasma exposure.
Protein expression and purification 2010;71(1):96-102.
2010: Priscilla L Yang; Alana Althage; Josan Chung; Holly Maier; Stefan F Wieland; Masanori Isogawa; Francis V Chisari
Immune effectors required for hepatitis B virus clearance.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(2):798-802.
2005: Susan L Uprichard; Bryan S Boyd; Alana Althage; Francis V Chisari
Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):773-8.
2003: Marianne M Martinic; Thomas Rülicke; Alana Althage; Bernhard Odermatt; Matthias Höchli; Alain Lamarre; Tilman Dumrese; Daniel E Speiser; Diego Kyburz; Hans Hengartner; Rolf M Zinkernagel
Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1861-6.
2003: Susan L Uprichard; Stefan F Wieland; Alana Althage; Francis V Chisari
Transcriptional and posttranscriptional control of hepatitis B virus gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1310-5.
2002: Priscilla L Yang; Alana Althage; Josan Chung; Francis V Chisari
Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13825-30.
2002: Marcus Pericin; Alana Althage; Stefan Freigang; Hans Hengartner; Eric Rolland; philippe Dupraz; Bernard Thorens; Patrick Aebischer; Rolf M Zinkernagel
Allogeneic beta-islet cells correct diabetes and resist immune rejection.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8203-6.
2000: Urs Karrer; Alana Althage; Bernhard Odermatt; Hans Hengartner; Rolf M Zinkernagel
Immunodeficiency of alymphoplasia mice (aly/aly) in vivo: structural defect of secondary lymphoid organs and functional B cell defect.
European journal of immunology 2000;30(10):2799-807.
1999: Adrian F Ochsenbein; Urs Karrer; Paul Klenerman; Alana Althage; Adrian Ciurea; H Shen; J F Miller; J L Whitton; Hans Hengartner; Rolf M Zinkernagel
A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9293-8.
1999: Rolf M Zinkernagel; Alana Althage
On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):8092-7.
1997: Martin F Bachmann; Ulrich Kalinke; Alana Althage; G Freer; C Burkhart; H Roost; M Aguet; Hans Hengartner; Rolf M Zinkernagel
The role of antibody concentration and avidity in antiviral protection.
Science (New York, N.Y.) 1997;276(5321):2024-7.
1997: Urs Karrer; Alana Althage; Bernhard Odermatt; Charles M Roberts; S J Korsmeyer; S Miyawaki; Hans Hengartner; Rolf M Zinkernagel
On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice.
The Journal of experimental medicine 1997;185(12):2157-70.
1994: D Lindemann; R Wilhelm; P Renard; Alana Althage; Rolf M Zinkernagel; J Mous
Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene.
The Journal of experimental medicine 1994;179(3):797-807.
1993: J Rothe; W Lesslauer; H Lötscher; Y Lang; P Koebel; F Köntgen; Alana Althage; Rolf M Zinkernagel; M Steinmetz; Horst Bluethmann
Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes.
Nature 1993;364(6440):798-802.
1993: S Huang; W Hendriks; Alana Althage; Silvio Hemmi; Horst Bluethmann; R Kamijo; Jan Vilcek; Rolf M Zinkernagel; M Aguet
Immune response in mice that lack the interferon-gamma receptor.
Science (New York, N.Y.) 1993;259(5102):1742-5.
1992: TM Kündig; Alana Althage; Hans Hengartner; Rolf M Zinkernagel
Skin test to assess virus-specific cytotoxic T-cell activity.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7757-61.
1992: Alana Althage; B Odermatt; Dimitrios Moskofidis; TM Kündig; Urs Hoffmann-Rohrer; Hans Hengartner; Rolf M Zinkernagel
Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation.
European journal of immunology 1992;22(7):1803-12.
1991: M Battegay; S Cooper; Alana Althage; J Bänziger; Hans Hengartner; Rolf M Zinkernagel
Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates.
Journal of virological methods 1991;33(1-2):191-8.
1989: T Leist; Alana Althage; E Haenseler; Hans Hengartner; Rolf M Zinkernagel
Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated.
The Journal of experimental medicine 1989;170(1):269-77.
1989: E Rüedi; M Sykes; Suzanne Ildstad; C H Chester; Alana Althage; Hans Hengartner; D H Sachs; Rolf M Zinkernagel
Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras.
Cellular immunology 1989;121(1):185-95.
1988: Rolf M Zinkernagel; E Rüedi; Alana Althage; Hans Hengartner; G Reimann
Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells.
The Journal of experimental medicine 1988;168(3):1187-92.
1988: H Roost; S Charan; Rita Gobet; E Rüedi; Hans Hengartner; Alana Althage; Rolf M Zinkernagel
An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus.
European journal of immunology 1988;18(4):511-8.
1988: L Stitz; Hans Hengartner; Alana Althage; Rolf M Zinkernagel
An easy and rapid method to screen large numbers of antibodies against internal cellular determinants.
Journal of immunological methods 1988;106(2):211-6.
1986: Rolf M Zinkernagel; E Haenseler; T Leist; A Cerny; Hans Hengartner; Alana Althage
T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay?
The Journal of experimental medicine 1986;164(4):1075-92.
1985: Rolf M Zinkernagel; T Leist; Hans Hengartner; Alana Althage
Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D.
The Journal of experimental medicine 1985;162(6):2125-41.
1985: Lothar Stitz; Alana Althage; Hans Hengartner; Rolf M Zinkernagel
Natural killer cells vs cytotoxic T cells in the peripheral blood of virus-infected mice.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(1):598-602.