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Larry David

Research Profile

Anatomy

Crystalline Lens

Chemicals & Drugs

Disorders

Cataract

Living Beings

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

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TOP 3
Jung-Bum Shin; Kateri J Spinelli; Andrew N Tauscher; Phillip A Wilmarth; Hongyu Zhao; Manfred Auer; Dongseok Choi; Larry L David; Ahmed Hassan; Erin D Jeffery; Jocelyn F Krey; Zoltan Metlagel; James M Pagana; Nicholas E Sherman; Peter G Barr-Gillespie
Molecular architecture of the chick vestibular hair bundle.
Angus C Grey; Jun Han; Rosica S Petrova; Larry L David; Paul J Donaldson; Kerry L Walker; Phillip A Wilmarth; Kevin L Schey
Verification and spatial localization of aquaporin-5 in the ocular lens.
Frank Giblin; Victor R Leverenz; Larry L David; Phillip A Wilmarth; M Francis Simpanya
Shotgun proteomic analysis of S-thiolation sites of guinea pig lens nuclear crystallins following oxidative stress in vivo.

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2013: Jung-Bum Shin; Kateri J Spinelli; Andrew N Tauscher; Phillip A Wilmarth; Hongyu Zhao; Manfred Auer; Dongseok Choi; Larry L David; Ahmed Hassan; Erin D Jeffery; Jocelyn F Krey; Zoltan Metlagel; James M Pagana; Nicholas E Sherman; Peter G Barr-Gillespie
Molecular architecture of the chick vestibular hair bundle.
Nature neuroscience 2013;16(3):365-74.
2013: Angus C Grey; Jun Han; Rosica S Petrova; Larry L David; Paul J Donaldson; Kerry L Walker; Phillip A Wilmarth; Kevin L Schey
Verification and spatial localization of aquaporin-5 in the ocular lens.
Experimental eye research 2013;108():94-102.
2013: Frank Giblin; Victor R Leverenz; Larry L David; Phillip A Wilmarth; M Francis Simpanya
Shotgun proteomic analysis of S-thiolation sites of guinea pig lens nuclear crystallins following oxidative stress in vivo.
Molecular vision 2013;19():267-80.
2013: Arpita S Bharadwaj; Timothy J Chipps; Dongseok Choi; Larry L David; Yuzhen Pan; Binoy Appukuttan; Eric E Benedetti; Andrew J Stempel; Phillip A Wilmarth; David O Zamora; Justine R Smith
Role of the retinal vascular endothelial cell in ocular disease.
Progress in retinal and eye research 2013;32():102-80.
2012: Melanie A Jackson; Charles T Roberts; Nicholas Caputo; Jessica R Castle; Larry L David; W Kenneth Ward
Stable liquid glucagon formulations for rescue treatment and bi-hormonal closed-loop pancreas.
Current diabetes reports 2012;12(6):705-10.
2012: Kirsten J Lampi; Cade B Fox; Larry L David
Changes in solvent accessibility of wild-type and deamidated βB2-crystallin following complex formation with αA-crystallin.
Experimental eye research 2012;104():48-58.
2012: Phillip A Wilmarth; Larry L David; Oliver Fiehn; Svetlana Lutsenko; Kristopher K Short; Jason L Burkhead
A systems approach implicates nuclear receptor targeting in the Atp7b(-/-) mouse model of Wilson's disease.
Metallomics : integrated biometal science 2012;4(7):660-8.
2012: Roger J W Truscott; Phillip A Wilmarth; Michael J Davies; Michael G Friedrich; Michelle Y Hooi; Joanne F Jamie; Brian Lyons; Jasminka Mizdrak; Larry L David
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Experimental eye research 2012;99():48-54.
2012: Kateri J Spinelli; Phillip A Wilmarth; Dongseok Choi; Larry L David; John E Klimek; Jung-Bum Shin; Peter G Gillespie
Distinct energy metabolism of auditory and vestibular sensory epithelia revealed by quantitative mass spectrometry using MS2 intensity.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(5):E268-77.
2011: Yoshihiro Matsumura; Larry L David; William R Skach
Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation.
Molecular biology of the cell 2011;22(16):2797-809.
2011: Suzanne S Fei; Robert J Hitzemann; Shannon K McWeeney; Phillip A Wilmarth; John K Belknap; Larry L David
Protein database and quantitative analysis considerations when integrating genetics and proteomics to compare mouse strains.
Journal of proteome research 2011;10(7):2905-12.
2011: Roman M Kassa; Nyamabo L Kasensa; Victor H Monterroso; Robert J Kayton; John E Klimek; Larry L David; Kalala R Lunganza; Kazadi T Kayembe; Marina Bentivoglio; Sharon L Juliano; Desire Tshala-Katumbay
On the biomarkers and mechanisms of konzo, a distinct upper motor neuron disease associated with food (cassava) cyanogenic exposure.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(3):571-8.
2011: Xiuhong Feng; Torben Feistel; Cosmo Buffalo; Ashley McCormack; Elizabeth Kruvand; Dayana D Rodriguez; Natalia S Akopyants; P K Umasankar; Larry L David; Armando Jardim; Stephen M Beverley; Scott M Landfear
Remodeling of protein and mRNA expression in Leishmania mexicana induced by deletion of glucose transporter genes.
Molecular and biochemical parasitology 2011;175(1):39-48.
2010: Takumi Takata; Joshua P Smith; Brian Arbogast; Larry L David; Kirsten J Lampi
Solvent accessibility of betaB2-crystallin and local structural changes due to deamidation at the dimer interface.
Experimental eye research 2010;91(3):336-46.
2010: Jung-Bum Shin; Chantal M Longo-Guess; Leona H Gagnon; Katherine W Saylor; Rachel A Dumont; Kateri J Spinelli; James M Pagana; Phillip A Wilmarth; Larry L David; Peter G Gillespie; Kenneth R Johnson
The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(29):9683-94.
2010: Glenn R Gourley; Libang Yang; Leeann Higgins; Michael A Riviere; Larry L David
Proteomic analysis of biopsied human colonic mucosa.
Journal of pediatric gastroenterology and nutrition 2010;51(1):46-54.
2010: Fei-Fei Yan; Emily B Pratt; Pei-Chun Chen; Fang Wang; William R Skach; Larry L David; Show-Ling Shyng
Role of Hsp90 in biogenesis of the beta-cell ATP-sensitive potassium channel complex.
Molecular biology of the cell 2010;21(12):1945-54.
2010: Shinji Honda; Zachary A Lewis; Maite Huarte; Lucy Y Cho; Larry L David; Yang Shi; Eric U Selker
The DMM complex prevents spreading of DNA methylation from transposons to nearby genes in Neurospora crassa.
Genes & development 2010;24(5):443-54.
2009: Jae W Dugan; Amador Albor; Larry L David; Jonathan Fowlkes; Marc T Blackledge; Tammy M Martin; Stephen R Planck; Holly L Rosenzweig; James T Rosenbaum; Michael P Davey
Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells.
Molecular immunology 2009;47(2-3):560-6.
2009: Lisa A Brennan; Wanda Lee; Frank J Giblin; Larry L David; Marc Kantorow
Methionine sulfoxide reductase A (MsrA) restores alpha-crystallin chaperone activity lost upon methionine oxidation.
Biochimica et biophysica acta 2009;1790(12):1665-72.
2009: Emi Nakajima; Larry L David; Michael A Riviere; M Azuma; Thomas R Shearer
Human and monkey lenses cultured with calcium ionophore form alphaB-crystallin lacking the C-terminal lysine, a prominent feature of some human cataracts.
Investigative ophthalmology & visual science 2009;50(12):5828-36.
2009: David J Rozansky; Tonya Cornwall; Arohan R Subramanya; Shaunessy Rogers; Yong-Feng Yang; Larry L David; Xiaoman Zhu; Chao-Ling Yang; David H Ellison
Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.
The Journal of clinical investigation 2009;119(9):2601-12.
2009: Surendra Dasari; Phillip A Wilmarth; Ashok Reddy; Lucinda J G Robertson; Srinivasa R Nagalla; Larry L David
Quantification of isotopically overlapping deamidated and 18o-labeled peptides using isotopic envelope mixture modeling.
Journal of proteome research 2009;8(3):1263-70.
2009: Steven Bassnett; Phillip A Wilmarth; Larry L David
The membrane proteome of the mouse lens fiber cell.
Molecular vision 2009;15():2448-63.
2008: Veronica Flood; Hamid A Al-Mondhiry; Chantelle Rein; Kristine S Alexander; Rehana S Lovely; Kelley M Shackleton; Larry L David; David H Farrell
Fibrinogen Hershey IV: a novel dysfibrinogen with a gammaV411I mutation in the integrin alpha(IIb)beta(3) binding site.
Thrombosis and haemostasis 2008;99(6):1008-12.
2008: Lucinda J G Robertson; Larry L David; Michael A Riviere; Phillip A Wilmarth; Matthew S Muir; Jim D Morton
Susceptibility of ovine lens crystallins to proteolytic cleavage during formation of hereditary cataract.
Investigative ophthalmology & visual science 2008;49(3):1016-22.
2008: Mukoma F Simpanya; Graeme Wistow; James Gao; Larry L David; Frank Giblin; kenneth mitton
Expressed sequence tag analysis of guinea pig (Cavia porcellus) eye tissues for NEIBank.
Molecular vision 2008;14():2413-27.
2008: Stephen Tanner; Samuel H Payne; Surendra Dasari; Zhouxin Shen; Phillip A Wilmarth; Larry L David; William F Loomis; Steven P Briggs; Vineet Bafna
Accurate annotation of peptide modifications through unrestrictive database search.
Journal of proteome research 2008;7(1):170-81.
2007: Andrew G Purkiss; Orval A Bateman; Keith Wyatt; Phillip A Wilmarth; Larry L David; Graeme Wistow; Christine Slingsby
Biophysical properties of gammaC-crystallin in human and mouse eye lens: the role of molecular dipoles.
Journal of molecular biology 2007;372(1):205-22.
2007: Surendra Dasari; Phillip A Wilmarth; D Leif Rustvold; Michael A Riviere; Srinivasa R Nagalla; Larry L David
Reliable detection of deamidated peptides from lens crystallin proteins using changes in reversed-phase elution times and parent ion masses.
Journal of proteome research 2007;6(9):3819-26.
2007: David O Zamora; Michael Riviere; Dongseok Choi; Yuzhen Pan; Stephen R Planck; James T Rosenbaum; Larry L David; Justine R Smith
Proteomic profiling of human retinal and choroidal endothelial cells reveals molecular heterogeneity related to tissue of origin.
Molecular vision 2007;13():2058-65.
2006: Emi Nakajima; Larry L David; Cory Bystrom; Thomas R Shearer; M Azuma
Calpain-specific proteolysis in primate retina: Contribution of calpains in cell death.
Investigative ophthalmology & visual science 2006;47(12):5469-75.
2006: Phillip A Wilmarth; Stephen Tanner; Surendra Dasari; Srinivasa R Nagalla; Michael A Riviere; Vineet Bafna; Pavel A Pevzner; Larry L David
Age-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: does deamidation contribute to crystallin insolubility?
Journal of proteome research 2006;5(10):2554-66.
2006: Marjorie Shih; Hong Ma; Emi Nakajima; Larry L David; M Azuma; Thomas R Shearer
Biochemical properties of lens-specific calpain Lp85.
Experimental eye research 2006;82(1):146-52.
2005: Graeme Wistow; Keith Wyatt; Larry L David; Chun Gao; Orval A Bateman; Steven L Bernstein; Stanislav I Tomarev; Lorenzo Segovia; Christine Slingsby; Thomas S Vihtelic
gammaN-crystallin and the evolution of the betagamma-crystallin superfamily in vertebrates.
The FEBS journal 2005;272(9):2276-91.
2005: Toru Shibatani; Larry L David; Ashley L McCormack; Klaus J Frueh; William R Skach
Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.
Biochemistry 2005;44(16):5982-92.
2005: Brian C Searle; Surendra Dasari; Phillip A Wilmarth; Mark Turner; Ashok Reddy; Larry L David; Srinivasa R Nagalla
Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm.
Journal of proteome research 2005;4(2):546-54.
2005: Eric J Carlson; Nathan Bays; Larry L David; William R Skach
Reticulocyte lysate as a model system to study endoplasmic reticulum membrane protein degradation.
Methods in molecular biology (Clifton, N.J.) 2005;301():185-205.
2004: Melinda K Duncan; Leike Xie; Larry L David; Michael L Robinson; Jennifer R Taube; Wenwu Cui; Lixing W Reneker
Ectopic Pax6 expression disturbs lens fiber cell differentiation.
Investigative ophthalmology & visual science 2004;45(10):3589-98.
2004: Phillip A Wilmarth; Michael A Riviere; D Leif Rustvold; Jeffrey D Lauten; Theresa E Madden; Larry L David
Two-dimensional liquid chromatography study of the human whole saliva proteome.
Journal of proteome research 2004;3(5):1017-23.
2004: Mushui Dai; Shelya X Zeng; Yetao Jin; Xiao-Xin Sun; Larry L David; Hua lu
Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition.
Molecular and cellular biology 2004;24(17):7654-68.
2004: Phillip A Wilmarth; Jennifer R Taube; Michael A Riviere; Melinda K Duncan; Larry L David
Proteomic and sequence analysis of chicken lens crystallins reveals alternate splicing and translational forms of beta B2 and beta A2 crystallins.
Investigative ophthalmology & visual science 2004;45(8):2705-15.
2004: Brian C Searle; Surendra Dasari; Mark Turner; Ashok Reddy; Dongseok Choi; Phillip A Wilmarth; Ashley L McCormack; Larry L David; Srinivasa R Nagalla
High-throughput identification of proteins and unanticipated sequence modifications using a mass-based alignment algorithm for MS/MS de novo sequencing results.
Analytical chemistry 2004;76(8):2220-30.
2004: Jun Han; Mark Little; Larry L David; Frank Giblin; Kevin L Schey
Sequence and peptide map of guinea pig aquaporin 0.
Molecular vision 2004;10():215-22.
2004: Michael Harms; Phillip A Wilmarth; Deborah M Kapfer; Eric A Steel; Larry L David; Hans Peter Bächinger; Kirsten J Lampi
Laser light-scattering evidence for an altered association of beta B1-crystallin deamidated in the connecting peptide.
Protein science : a publication of the Protein Society 2004;13(3):678-86.
2003: Shuh-Tuan Wang-Su; Ashley L McCormack; Shaojun Yang; Matthew R Hosler; April Mixon; Michael A Riviere; Phillip A Wilmarth; Usha P Andley; Donita Garland; Hong Li; Larry L David; BJ Wagner
Proteome analysis of lens epithelia, fibers, and the HLE B-3 cell line.
Investigative ophthalmology & visual science 2003;44(11):4829-36.
2003: Qishen Pang; Tracy A Christianson; Tara Koretsky; Hanqian Carlson; Larry L David; Winifred Keeble; Gregory R Faulkner; Ashley Speckhart; Grover C Bagby
Nucleophosmin interacts with and inhibits the catalytic function of eukaryotic initiation factor 2 kinase PKR.
The Journal of biological chemistry 2003;278(43):41709-17.
2002: Yung Hae Kim; Deborah M Kapfer; Jos Boekhorst; Nicolette H Lubsen; Hans Peter Bächinger; Thomas R Shearer; Larry L David; Jimmy B Feix; Kirsten J Lampi
Deamidation, but not truncation, decreases the urea stability of a lens structural protein, betaB1-crystallin.
Biochemistry 2002;41(47):14076-84.
2002: Kirsten J Lampi; Yung H Kim; Hans Peter Bächinger; Bruce A Boswell; Robyn A Lindner; John A Carver; Thomas R Shearer; Larry L David; Deborah M Kapfer
Decreased heat stability and increased chaperone requirement of modified human betaB1-crystallins.
Molecular vision 2002;8():359-66.
2002: Wenjie Li; Harold I Calvin; Larry L David; kaili wu; Ashley L McCormack; Guan-Ping Zhu; S-C Joseph Fu
Altered patterns of phosphorylation in cultured mouse lenses during development of buthionine sulfoximine cataracts.
Experimental eye research 2002;75(3):335-46.
2002: Jennifer R Taube; Chun Y Gao; Yoji Ueda; Peggy S Zelenka; Larry L David; Melinda K Duncan
General utility of the chicken betaB1-crystallin promoter to drive protein expression in lens fiber cells of transgenic mice.
Transgenic research 2002;11(4):397-410.
2002: Yoji Ueda; Chiho Fukiage; Marjorie Shih; Thomas R Shearer; Larry L David
Mass measurements of C-terminally truncated alpha-crystallins from two-dimensional gels identify Lp82 as a major endopeptidase in rat lens.
Molecular & cellular proteomics : MCP 2002;1(5):357-65.
2002: Kirsten J Lampi; Marjorie Shih; Yoji Ueda; Thomas R Shearer; Larry L David
Lens proteomics: analysis of rat crystallin sequences and two-dimensional electrophoresis map.
Investigative ophthalmology & visual science 2002;43(1):216-24.
2002: Yoji Ueda; Melinda K Duncan; Larry L David
Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age.
Investigative ophthalmology & visual science 2002;43(1):205-15.
2001: Yoji Ueda; Ashley L McCormack; Thomas R Shearer; Larry L David
Purification and characterization of lens specific calpain (Lp82) from bovine lens.
Experimental eye research 2001;73(5):625-37.
2001: Zhongli Zhang; Larry L David; David L Smith; Jean B Smith
Resistance of human betaB2-crystallin to in vivo modification.
Experimental eye research 2001;73(2):203-11.
2001: Marjorie Shih; Larry L David; Kirsten J Lampi; H Ma; Chiho Fukiage; M Azuma; Thomas R Shearer
Proteolysis by m-calpain enhances in vitro light scattering by crystallins from human and bovine lenses.
Current eye research 2001;22(6):458-69.
2001: Kirsten J Lampi; J T Oxford; H P Bachinger; Thomas R Shearer; Larry L David; Deborah M Kapfer
Deamidation of human beta B1 alters the elongated structure of the dimer.
Experimental eye research 2001;72(3):279-88.
2000: Tian Xia; John C (Craig) Baumgartner; Larry L David
Isolation and identification of Prevotella tannerae from endodontic infections.
Oral microbiology and immunology 2000;15(4):273-5.
2000: Y Nakamura; Chiho Fukiage; Marjorie Shih; H Ma; Larry L David; M Azuma; Thomas R Shearer
Contribution of calpain Lp82-induced proteolysis to experimental cataractogenesis in mice.
Investigative ophthalmology & visual science 2000;41(6):1460-6.
1999: L J Odell; John C (Craig) Baumgartner; Tian Xia; Larry L David
Survey for collagenase gene prtC in Porphyromonas gingivalis and Porphyromonas endodontalis isolated from endodontic infections.
Journal of endodontics 1999;25(8):555-8.
1999: John I Clark; H Matsushima; Larry L David; J M Clark
Lens cytoskeleton and transparency: a model.
Eye (London, England) 1999;13 ( Pt 3b)():417-24.
1999: John C (Craig) Baumgartner; KS Bae; Tian Xia; J Whitt; Larry L David
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and polymerase chain reaction for differentiation of Prevotella intermedia and Prevotella nigrescens.
Journal of endodontics 1999;25(5):324-8.
1999: Kevin L Schey; JG Fowler; Thomas R Shearer; Larry L David
Modifications to rat lens major intrinsic protein in selenite-induced cataract.
Investigative ophthalmology & visual science 1999;40(3):657-67.
1998: Kirsten J Lampi; Z Ma; SR Hanson; M Azuma; Marjorie Shih; Thomas R Shearer; David L Smith; Jean B Smith; Larry L David
Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry.
Experimental eye research 1998;67(1):31-43.
1998: Z Ma; SR Hanson; Kirsten J Lampi; Larry L David; David L Smith; Jean B Smith
Age-related changes in human lens crystallins identified by HPLC and mass spectrometry.
Experimental eye research 1998;67(1):21-30.
1998: Yuri V Sergeev; Larry L David; H C Chen; John N Hope; J Fielding Hejtmancik
Local microdomain structure in the terminal extensions of betaA3- and betaB2-crystallins.
Molecular vision 1998;4():9.
1998: Marjorie Shih; Kirsten J Lampi; Thomas R Shearer; Larry L David
Cleavage of beta crystallins during maturation of bovine lens.
Molecular vision 1998;4():4.
1997: K S Bae; John C (Craig) Baumgartner; Thomas R Shearer; Larry L David
Occurrence of Prevotella nigrescens and Prevotella intermedia in infections of endodontic origin.
Journal of endodontics 1997;23(10):620-3.
1997: M Azuma; Chiho Fukiage; Larry L David; Thomas R Shearer
Activation of calpain in lens: a review and proposed mechanism.
Experimental eye research 1997;64(4):529-38.
1997: H Ma; Marjorie Shih; D B Throneberg; Larry L David; Thomas R Shearer
Changes in calpain II mRNA in young rat lens during maturation and cataract formation.
Experimental eye research 1997;64(3):437-45.
1997: H Matsushima; Larry L David; T Hiraoka; John I Clark
Loss of cytoskeletal proteins and lens cell opacification in the selenite cataract model.
Experimental eye research 1997;64(3):387-95.
1997: Kirsten J Lampi; Z Ma; Marjorie Shih; Thomas R Shearer; Jean B Smith; David L Smith; Larry L David
Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.
The Journal of biological chemistry 1997;272(4):2268-75.
1996: Thomas R Shearer; Marjorie Shih; T Mizuno; Larry L David
Crystallins from rat lens are especially susceptible to calpain-induced light scattering compared to other species.
Current eye research 1996;15(8):860-8.
1996: Larry L David; Kirsten J Lampi; A L Lund; Jean B Smith
The sequence of human betaB1-crystallin cDNA allows mass spectrometric detection of betaB1 protein missing portions of its N-terminal extension.
The Journal of biological chemistry 1996;271(8):4273-9.
1995: Thomas R Shearer; Marjorie Shih; M Azuma; Larry L David
Precipitation of crystallins from young rat lens by endogenous calpain.
Experimental eye research 1995;61(2):141-50.
1995: N Iwasaki; Larry L David; Thomas R Shearer
Crystallin degradation and insolubilization in regions of young rat lens with calcium ionophore cataract.
Investigative ophthalmology & visual science 1995;36(2):502-9.
1994: Larry L David; H I Calvin; S C Fu
Buthionine sulfoximine induced cataracts in mice contain insolubilized crystallins with calpain II cleavage sites.
Experimental eye research 1994;59(4):501-4.
1994: Larry L David; M Azuma; Thomas R Shearer
Cataract and the acceleration of calpain-induced beta-crystallin insolubilization occurring during normal maturation of rat lens.
Investigative ophthalmology & visual science 1994;35(3):785-93.
1993: Mary J Kelley; Larry L David; N Iwasaki; Jay W Wright; Thomas R Shearer
alpha-Crystallin chaperone activity is reduced by calpain II in vitro and in selenite cataract.
The Journal of biological chemistry 1993;268(25):18844-9.
1993: Larry L David; Thomas R Shearer
Beta-crystallins insolubilized by calpain II in vitro contain cleavage sites similar to beta-crystallins insolubilized during cataract.
FEBS letters 1993;324(3):265-70.
1993: K Kadoya; M Azuma; Larry L David; Thomas R Shearer
Role of calpain in hydrogen peroxide induced cataract.
Current eye research 1993;12(4):341-6.
1993: Larry L David; Thomas R Shearer; Marjorie Shih
Sequence analysis of lens beta-crystallins suggests involvement of calpain in cataract formation.
The Journal of biological chemistry 1993;268(3):1937-40.
1992: M Azuma; Larry L David; Thomas R Shearer
Superior prevention of calcium ionophore cataract by E64d.
Biochimica et biophysica acta 1992;1180(2):215-20.
1992: Kirsten J Lampi; K Kadoya; M Azuma; Larry L David; Thomas R Shearer
Comparison of cell-permeable calpain inhibitors and E64 in reduction of cataract in cultured rat lenses.
Toxicology and applied pharmacology 1992;117(1):53-7.
1992: Kirsten J Lampi; Larry L David; Thomas R Shearer
Association of calpain with insoluble pellet of rat lens.
Experimental eye research 1992;55(2):369-75.
1992: Larry L David; Jay W Wright; Thomas R Shearer
Calpain II induced insolubilization of lens beta-crystallin polypeptides may induce cataract.
Biochimica et biophysica acta 1992;1139(3):210-6.
1992: M Azuma; R S Anderson; S Sameshima; T Matsumoto; Larry L David; Thomas R Shearer
Calpain in rat cornea.
Investigative ophthalmology & visual science 1992;33(8):2476-82.
1992: Thomas R Shearer; Larry L David; R S Anderson; M Azuma
Review of selenite cataract.
Current eye research 1992;11(4):357-69.
1992: M Azuma; Larry L David; Thomas R Shearer
Hydration and elevated calcium alone do not produce xylose nuclear cataract: role of proteolysis by calpain.
Ophthalmic research 1992;24(1):8-14.
1991: M Azuma; Larry L David; Thomas R Shearer
Cysteine protease inhibitor E64 reduces the rate of formation of selenite cataract in the whole animal.
Current eye research 1991;10(7):657-66.
1991: Thomas R Shearer; M Azuma; Larry L David; T Murachi
Amelioration of cataracts and proteolysis in cultured lenses by cysteine protease inhibitor E64.
Investigative ophthalmology & visual science 1991;32(3):533-40.
1991: R D Lipman; D E Cyr; Larry L David; Allen Taylor
Calpain in cultured bovine lens epithelial cells.
Current eye research 1991;10(1):11-7.
1990: M Azuma; Thomas R Shearer; T Matsumoto; Larry L David; T Murachi
Calpain II in two in vivo models of sugar cataract.
Experimental eye research 1990;51(4):393-401.
1990: Thomas R Shearer; M Azuma; Larry L David; Y Yamagata; T Murachi
Calpain and calpastatin in rabbit corneal epithelium.
Current eye research 1990;9(1):39-44.
1990: H Watanabe; M Komoto; Larry L David; Thomas R Shearer
Changes in crystallin concentration in rat aqueous and vitreous humors after selenium-induced reversible cortical cataract.
Japanese journal of ophthalmology 1990;34(4):472-8.
1989: M D Varnum; Larry L David; Thomas R Shearer
Age-related changes in calpain II and calpastatin in rat lens.
Experimental eye research 1989;49(6):1053-65.
1989: Larry L David; M D Varnum; Kirsten J Lampi; Thomas R Shearer
Calpain II in human lens.
Investigative ophthalmology & visual science 1989;30(2):269-75.
1989: Larry L David; Thomas R Shearer
Role of proteolysis in lenses: a review.
Lens and eye toxicity research 1989;6(4):725-47.
1988: James T Rosenbaum; B W Seymour; W Raymond; L Langlois; M Wu; Larry L David
Similar chemotactic factor for monocytes predominates in different animal models of uveitis.
Inflammation 1988;12(3):191-201.
1988: Larry L David; L J Takemoto; R S Anderson; Thomas R Shearer
Proteolytic changes in main intrinsic polypeptide (MIP26) from membranes in selenite cataract.
Current eye research 1988;7(4):411-7.
1987: James T Rosenbaum; John R Samples; B Seymour; L Langlois; Larry L David
Chemotactic activity of lens proteins and the pathogenesis of phacolytic glaucoma.
Archives of ophthalmology 1987;105(11):1582-4.
1987: K R Hightower; Larry L David; Thomas R Shearer
Regional distribution of free calcium in selenite cataract: relation to calpain II.
Investigative ophthalmology & visual science 1987;28(10):1702-6.
1987: Larry L David; B M Dickey; Thomas R Shearer
Origin of urea-soluble protein in the selenite cataract. Role of beta-crystallin proteolysis and calpain II.
Investigative ophthalmology & visual science 1987;28(7):1148-56.
1987: James T Rosenbaum; LM O'Rourke; G Davies; C Wenger; Larry L David; Joseph Robertson
Retinal pigment epithelial cells secrete substances that are chemotactic for monocytes.
Current eye research 1987;6(6):793-800.
1987: Thomas R Shearer; Larry L David; R S Anderson
Selenite cataract: a review.
Current eye research 1987;6(2):289-300.
1986: Thomas R Shearer; Larry L David; R S Anderson
Selenite decreases phase separation temperature in rat lens.
Experimental eye research 1986;42(5):503-6.
1986: Larry L David; Thomas R Shearer
Purification of calpain II from rat lens and determination of endogenous substrates.
Experimental eye research 1986;42(3):227-38.
1984: Larry L David; Thomas R Shearer
Calcium-activated proteolysis in the lens nucleus during selenite cataractogenesis.
Investigative ophthalmology & visual science 1984;25(11):1275-83.
1984: Larry L David; Thomas R Shearer
State of sulfhydryl in selenite cataract.
Toxicology and applied pharmacology 1984;74(1):109-15.
1982: Thomas R Shearer; Larry L David
Role of calcium in selenium cataract.
Current eye research 1982;2(11):777-84.
1980: M K Bhatnagar; S Yamashiro; Larry L David
Ultrastructural study of liver fibrosis in turkeys fed diets containing rapeseed meal.
Research in veterinary science 1980;29(2):260-5.