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James Davidson

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E S Jones; E Patricia Owen; James S Davidson; Lize van der Merwe; Brian Rayner
The R563Q mutation of the epithelial sodium channel beta-subunit is associated with hypertension.
M K Dhanjal; E Patricia Owen; J A Anthony; James S Davidson; Brian Rayner
Association of pre-eclampsia with the R563Q mutation of the beta-subunit of the epithelial sodium channel.
Adam J Pawson; Stuart Maudsley; John Lopes; Arieh A Katz; Yuh-Man Sun; James S Davidson; Robert P Millar
Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl-terminal tail Are critical.

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All Publications

2011: E S Jones; E Patricia Owen; James S Davidson; Lize van der Merwe; Brian Rayner
The R563Q mutation of the epithelial sodium channel beta-subunit is associated with hypertension.
Cardiovascular journal of Africa 2011;22(5):241-4.
2006: M K Dhanjal; E Patricia Owen; J A Anthony; James S Davidson; Brian Rayner
Association of pre-eclampsia with the R563Q mutation of the beta-subunit of the epithelial sodium channel.
BJOG : an international journal of obstetrics and gynaecology 2006;113(5):595-8.
2003: Adam J Pawson; Stuart Maudsley; John Lopes; Arieh A Katz; Yuh-Man Sun; James S Davidson; Robert P Millar
Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl-terminal tail Are critical.
Endocrinology 2003;144(9):3860-71.
2003: Brian Rayner; E Patricia Owen; Judy A King; Steven G Soule; Heleen Vreede; Lionel Henry Opie; David Marais; James S Davidson
A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.
Journal of hypertension 2003;21(5):921-6.
2001: Brian Rayner; J E Myers; Lionel Henry Opie; Yvonne A Trinder; James S Davidson
Screening for primary aldosteronism--normal ranges for aldosterone and renin in three South African population groups.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2001;91(7):594-9.
2001: Brian Rayner; Steven G Soule; James S Davidson
Primary aldosteronism--a new perspective in South Africa.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 2001;12(2):69-72.
2000: James N Hislop; M T Madziva; HM Everest; Tom Harding; James B Uney; Gary B Willars; Robert P Millar; Brigitte E Troskie; James S Davidson; Craig A McArdle
Desensitization and internalization of human and xenopus gonadotropin-releasing hormone receptors expressed in alphaT4 pituitary cells using recombinant adenovirus.
Endocrinology 2000;141(12):4564-75.
2000: Brian Rayner; Lionel Henry Opie; James S Davidson
The aldosterone/renin ratio as a screening test for primary aldosteronism.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2000;90(4):394-400.
2000: Steven G Soule; James S Davidson; Brian Rayner
The evaluation of primary hyperaldosteronism.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2000;90(4):387-94.
1999: D Assefa; Adam J Pawson; Craig A McArdle; Robert P Millar; Colleen A Flanagan; Roger W Roeske; James S Davidson
A new photoreactive antagonist cross-links to the N-terminal domain of the gonadotropin-releasing hormone receptor.
Molecular and cellular endocrinology 1999;156(1-2):179-88.
1999: Craig A McArdle; James S Davidson; Gary B Willars
The tail of the gonadotrophin-releasing hormone receptor: desensitization at, and distal to, G protein-coupled receptors.
Molecular and cellular endocrinology 1999;151(1-2):129-36.
1999: W Forrest-Owen; Gary B Willars; Stefan R Nahorski; D Assefa; James S Davidson; James N Hislop; Craig A McArdle
The lack of gonadotrophin-releasing hormone (GnRH) receptor desensitisation in alphaT3-1 cells is not due to GnRH receptor reserve or phosphatidylinositol 4,5-bis-phosphate pool size.
Molecular and cellular endocrinology 1999;147(1-2):161-73.
1998: D B Myburgh; Adam J Pawson; James S Davidson; Colleen A Flanagan; Robert P Millar; JP Hapgood
A single amino acid substitution in transmembrane helix VI results in overexpression of the human GnRH receptor.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(4):438-47.
1998: Colleen A Flanagan; Bernhard J Fromme; James S Davidson; Robert P Millar
A high affinity gonadotropin-releasing hormone (GnRH) tracer, radioiodinated at position 6, facilitates analysis of mutant GnRH receptors.
Endocrinology 1998;139(10):4115-9.
1998: Juan A Ballesteros; S Kitanovic; Frank Guarnieri; P Davies; Bernhard J Fromme; K Konvicka; L Chi; Robert P Millar; James S Davidson; HAREL WEINSTEIN; Stuart C Sealfon
Functional microdomains in G-protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor.
The Journal of biological chemistry 1998;273(17):10445-53.
1998: Adam J Pawson; A Katz; Yuh-Man Sun; J Lopes; Nicola Illing; Robert P Millar; James S Davidson
Contrasting internalization kinetics of human and chicken gonadotropin-releasing hormone receptors mediated by C-terminal tail.
The Journal of endocrinology 1998;156(3):R9-12.
1997: James S Davidson; D Assefa; Adam J Pawson; P Davies; JP Hapgood; I Becker; Colleen A Flanagan; Roger W Roeske; Robert Millar
Irreversible activation of the gonadotropin-releasing hormone receptor by photoaffinity cross-linking: localization of attachment site to Cys residue in N-terminal segment.
Biochemistry 1997;36(42):12881-9.
1996: Craig A McArdle; Gary B Willars; R C Fowkes; Stefan R Nahorski; James S Davidson; W Forrest-Owen
Desensitization of gonadotropin-releasing hormone action in alphaT3-1 cells due to uncoupling of inositol 1,4,5-trisphosphate generation and Ca2+ mobilization.
The Journal of biological chemistry 1996;271(39):23711-7.
1996: James S Davidson; Craig A McArdle; P Davies; R Elario; Colleen A Flanagan; Robert P Millar
Asn102 of the gonadotropin-releasing hormone receptor is a critical determinant of potency for agonists containing C-terminal glycinamide.
The Journal of biological chemistry 1996;271(26):15510-4.
1996: James S Davidson; Colleen A Flanagan; P D Davies; Janet Patricia Hapgood; D Myburgh; R Elario; Robert P Millar; W Forrest-Owen; Craig A McArdle
Incorporation of an additional glycosylation site enhances expression of functional human gonadotropin-releasing hormone receptor.
Endocrine 1996;4(3):207-12.
1996: Craig A McArdle; W Forrest-Owen; James S Davidson; R Fowkes; R Bunting; W T Mason; A Poch; M Kratzmeier
Ca2+ entry in gonadotrophs and alpha T3-1 cells: does store-dependent Ca2+ influx mediate gonadotrophin-releasing hormone action?
The Journal of endocrinology 1996;149(1):155-69.
1995: James S Davidson; Colleen A Flanagan; W Zhou; I I Becker; R Elario; W Emeran; Stuart C Sealfon; Robert P Millar
Identification of N-glycosylation sites in the gonadotropin-releasing hormone receptor: role in receptor expression but not ligand binding.
Molecular and cellular endocrinology 1995;107(2):241-5.
1994: Colleen A Flanagan; I I Becker; James S Davidson; I K Wakefield; W Zhou; Stuart C Sealfon; Robert P Millar
Glutamate 301 of the mouse gonadotropin-releasing hormone receptor confers specificity for arginine 8 of mammalian gonadotropin-releasing hormone.
The Journal of biological chemistry 1994;269(36):22636-41.
1994: James S Davidson; I K Wakefield; Robert P Millar
Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor.
The Biochemical journal 1994;300 ( Pt 2)():299-302.
1994: James S Davidson; Colleen A Flanagan; I I Becker; Nicola Illing; Stuart C Sealfon; Robert P Millar
Molecular function of the gonadotropin-releasing hormone receptor: insights from site-directed mutagenesis.
Molecular and cellular endocrinology 1994;100(1-2):9-14.
1994: W Zhou; Colleen A Flanagan; J A Ballesteros; K Konvicka; James S Davidson; HAREL WEINSTEIN; Robert P Millar; Stuart C Sealfon
A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor.
Molecular pharmacology 1994;45(2):165-70.
1993: Nicola Illing; G F Jacobs; I I Becker; Colleen A Flanagan; James S Davidson; A Eales; W Zhou; Stuart C Sealfon; Robert P Millar
Comparative sequence analysis and functional characterization of the cloned sheep gonadotropin-releasing hormone receptor reveal differences in primary structure and ligand specificity among mammalian receptors.
Biochemical and biophysical research communications 1993;196(2):745-51.
1993: James S Davidson; A Eales; Roger W Roeske; Robert P Millar
Inhibition of pituitary hormone exocytosis by a synthetic peptide related to the rab effector domain.
FEBS letters 1993;326(1-3):219-21.
1993: James S Davidson; S E Franco; Robert P Millar
Stimulation by Mn2+ and inhibition by Cd2+, Zn2+, Ni2+, and Co2+ ions of luteinizing hormone exocytosis at an intracellular site.
Endocrinology 1993;132(6):2654-8.
1993: L Chi; W Zhou; A Prikhozhan; Colleen A Flanagan; James S Davidson; Myriam Golembo; Nicola Illing; Robert P Millar; Stuart C Sealfon
Cloning and characterization of the human GnRH receptor.
Molecular and cellular endocrinology 1993;91(1-2):R1-6.
1992: James S Davidson; I K Wakefield; Philip van der Merwe; Robert P Millar
Involvement of pertussis toxin-sensitive and -insensitive GTP-binding proteins in luteinizing hormone exocytosis distal to second messenger generation.
Cellular signalling 1992;4(4):379-84.
1992: P V Kaye; Philip van der Merwe; Robert P Millar; James S Davidson
Arachidonic acid-induced LH release is ATP-independent and insensitive to N-ethyl maleimide.
The Journal of endocrinology 1992;132(1):77-82.
1991: Philip van der Merwe; Robert P Millar; I K Wakefield; James S Davidson
Inhibition of luteinizing-hormone exocytosis by guanosine 5'-[gamma-thio]triphosphate reveals involvement of a GTP-binding protein distal to second-messenger generation.
The Biochemical journal 1991;275 ( Pt 2)():399-405.
1990: M B Macrae; James S Davidson; Robert P Millar; Philip van der Merwe
Cyclic AMP stimulates luteinizing-hormone (lutropin) exocytosis in permeabilized sheep anterior-pituitary cells. Synergism with protein kinase C and calcium.
The Biochemical journal 1990;271(3):635-9.
1990: Philip van der Merwe; Robert P Millar; I K Wakefield; M B Macrae; James S Davidson
Staurosporine enhances gonadotrophin-releasing hormone-stimulated luteinizing hormone secretion.
FEBS letters 1990;267(1):111-3.
1990: Philip van der Merwe; Robert P Millar; James S Davidson
Calcium stimulates luteinizing-hormone (lutropin) exocytosis by a mechanism independent of protein kinase C.
The Biochemical journal 1990;268(2):493-8.
1990: James S Davidson; I K Wakefield; U Sohnius; Philip van der Merwe; Robert P Millar
A novel extracellular nucleotide receptor coupled to phosphoinositidase-C in pituitary cells.
Endocrinology 1990;126(1):80-7.
1989: Philip van der Merwe; Robert P Millar; I K Wakefield; James S Davidson
Mechanisms of luteinizing-hormone exocytosis in Staphylococcus aureus-alpha-toxin-permeabilized sheep gonadotropes.
The Biochemical journal 1989;264(3):901-8.
1989: J Fine; P Cole; James S Davidson
Extracellular nucleotides stimulate receptor-mediated calcium mobilization and inositol phosphate production in human fibroblasts.
The Biochemical journal 1989;263(2):371-6.
1989: C E Smith; James S Davidson; Robert P Millar
Ba2+ stimulation of luteinizing-hormone release demonstrates two mechanisms of Ca2+ entry in gonadotrope cells.
The Biochemical journal 1989;259(1):217-21.
1989: J A King; James S Davidson; A E Mehl; I K Wakefield; P B Andersson; Robert P Millar
Gonadal steroid modulation of signal transduction and luteinizing hormone release in cultured chicken pituitary cells.
Endocrinology 1989;124(4):1830-40.
1989: G P Mulligan; James S Davidson; H Kaplan; M J Abrahamson
Euthyroid hyperthyroxinaemia due to endogenous antibodies to thyroxine and tri-iodothyronine. A case report.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1989;75(4):181-3.
1989: Philip van der Merwe; I K Wakefield; J Fine; Robert P Millar; James S Davidson
Extracellular adenosine triphosphate activates phospholipase C and mobilizes intracellular calcium in primary cultures of sheep anterior pituitary cells.
FEBS letters 1989;243(2):333-6.
1988: James S Davidson; I M Baumgarten
Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships.
The Journal of pharmacology and experimental therapeutics 1988;246(3):1104-7.
1988: A Rosen; Philip van der Merwe; James S Davidson
Effects of SV40 transformation on intercellular gap junctional communication in human fibroblasts.
Cancer research 1988;48(12):3485-9.
1988: J A King; James S Davidson; Robert P Millar
Interaction of endogenous chicken gonadotrophin-releasing hormone-I and -II on chicken pituitary cells.
The Journal of endocrinology 1988;117(1):43-9.
1988: James S Davidson; I K Wakefield; J A King; G P Mulligan; Robert P Millar
Dual pathways of calcium entry in spike and plateau phases of luteinizing hormone release from chicken pituitary cells: sequential activation of receptor-operated and voltage-sensitive calcium channels by gonadotropin-releasing hormone.
Molecular endocrinology (Baltimore, Md.) 1988;2(4):382-90.
1987: C E Smith; I Wakefield; J A King; Z Naor; Robert P Millar; James S Davidson
The initial phase of GnRH-stimulated LH release from pituitary cells is independent of calcium entry through voltage-gated channels.
FEBS letters 1987;225(1-2):247-50.
1987: Robert P Millar; J A King; James S Davidson; R C Milton
Gonadotrophin-releasing hormone--diversity of functions and clinical applications.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1987;72(11):748-55.
1987: James S Davidson; I Wakefield; J A King; Robert P Millar
Barium-induced LH release from chicken pituitary cells: synergism with phorbol ester.
The Journal of endocrinology 1987;114(1):11-6.
1986: James S Davidson; I M Baumgarten; Eric Harley
Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid.
Biochemical and biophysical research communications 1986;134(1):29-36.
1985: James S Davidson; I M Baumgarten; Eric Harley
Inhibition of intercellular junctional communication in human fibroblasts by triphenylmethane, triphenylmethylchloride, tetraphenylboron and related compounds.
Biochimica et biophysica acta 1985;847(1):1-7.
1985: James S Davidson; I M Baumgarten; Eric Harley
Studies on the mechanism of phorbol ester-induced inhibition of intercellular junctional communication.
Carcinogenesis 1985;6(9):1353-8.
1985: James S Davidson; I M Baumgarten; E H Harley
Effects of 12-O-tetradecanoylphorbol-13-acetate and retinoids on intercellular junctional communication measured with a citrulline incorporation assay.
Carcinogenesis 1985;6(4):645-50.
1984: James S Davidson; I M Baumgarten; Eric Harley
Effects of extracellular calcium and magnesium on junctional intercellular communication in human fibroblasts.
Experimental cell research 1984;155(2):406-12.
1984: James S Davidson; I M Baumgarten; Eric Harley
Metabolic cooperation between argininosuccinate synthetase and argininosuccinate lyase deficient human fibroblasts.
Experimental cell research 1984;150(2):367-78.